Lu Shiou-Ling ＬＵＳＨＩＯＵＬＩＮＧ

… Alternative Names

LU SHIOULING ルシヨオリン

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Researcher Number	80830083
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院歯学研究科, 助教
Affiliation (based on the past Project Information) *help	2025: 大阪大学, 大学院歯学研究科, 助教 2022 – 2023: 大阪大学, 大学院歯学研究科, 助教 2021: 大阪大学, 歯学研究科, 助教 2018 – 2020: 大阪大学, 歯学研究科, 特任助教 2019: 大阪大学, 歯学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 44010:Cell biology-related / 0907:Oral science and related fields
Keywords	Principal Investigator Group A Streptococcus / 化膿レンサ球菌 / Group A streptococcus / endothelial cell / vegf / Bacteria / Autophagy / TFEB / Endothelial cell / VEGF … More / 内皮細胞 / Macrophage / microautophagy / Rab38 / Rab32 / マクロファージ Less

Rab32-LROによるマクロファージ殺菌機構の解明Principal Investigator
- Principal Investigator
  
  LU SHIOULING
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  The University of Osaka
Study the mechanism how Rab32/Rab38 positive lysosome related organelle is involved in bacteria suppression through macroautophagy and microautophagy in macrophage and mouse infectious model.Principal Investigator
- Principal Investigator
  
  Lu Shiou-Ling
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Osaka University
Study the antimicrobial activity of VEGF-TFEB for endothelial cells defense against group A streptococcus infection.Principal Investigator
- Principal Investigator
  
  Lu Shiou-Ling
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0907:Oral science and related fields
- Research Institution
  Osaka University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Rab32 and Rab38 maintain bone homeostasis by regulating intracellular traffic in osteoclasts2023
- Author(s)
  K. Tokuda, S.-L. Lu, Z. Zidi, Y. Kato, S. Chen, K. Noda, K.i Hirose, Y. Usami, N. Uzawa, S. Murakami S. Murakami S. Toyosawa M.Fukuda G-H Sun-Wada Y. Wada T. Noda
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 48 Issue: 2 Pages: 223-239
- DOI
  10.1247/csf.23061
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06553, KAKENHI-PROJECT-20K15789, KAKENHI-PUBLICLY-22H04645
[Journal Article] Characterization of Rab32- and Rab38-positive lysosome-related organelles in osteoclasts and macrophages.2023
- Author(s)
  1.Noda, K., Tokuda K., Hao F., Wada Y., Sun-Wada, GH. Murakami S., Fukuda M., Ito T., and Noda T.
- Journal Title
  
  J. Biol Chem.
  
  Volume: 299 Issue: 10 Pages: 105191-105191
- DOI
  10.1016/j.jbc.2023.105191
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06553, KAKENHI-PROJECT-20K15789, KAKENHI-PUBLICLY-22H04645
[Journal Article] 血管内皮細胞増殖因子の新たな役割：殺菌作業増強効果の発見2023
- Author(s)
  Shiou-Ling Lu, 野田健司
- Journal Title
  
  4.大阪大学歯学部雑誌
  
  Volume: 67 Pages: 17-19
- Data Source
  KAKENHI-PROJECT-20K15789
[Journal Article] Opposing roles of RUBCN isoforms in autophagy and memory B cell generation2023
- Author(s)
  Tsai Chao-Yuan、Sakakibara Shuhei、Kuan Yu-Diao、Omori Hiroko、El Hussien Maruwa Ali、Okuzaki Daisuke、Lu Shiou-Ling、Noda Takeshi、Tabata Keisuke、Nakamura Shuhei、Yoshimori Tamotsu、Kikutani Hitoshi
- Journal Title
  
  Science Signaling
  
  Volume: 16 Issue: 803 Pages: 1-15
- DOI
  10.1126/scisignal.ade3599
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06169, KAKENHI-PROJECT-20K15789, KAKENHI-PROJECT-22H04982, KAKENHI-PROJECT-23K27671
[Journal Article] オートファジーは健康寿命に寄与するか？2022
- Author(s)
  野田健司、Shiou-Ling Lu
- Journal Title
  
  大阪歯科保険医新聞
  
  Volume: 1445
- Open Access
- Data Source
  KAKENHI-PROJECT-20K15789
[Journal Article] VEGF (vascular endothelial growth factor) provides antimicrobial effects via autophagy and lysosomal empowerment in endothelial cells2022
- Author(s)
  Lu Shiou-Ling、Noda Takeshi
- Journal Title
  
  Autophagy Reports
  
  Volume: 1 Issue: 1 Pages: 555-558
- DOI
  10.1080/27694127.2022.2137755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15789
[Journal Article] VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes2022
- Author(s)
  Lu Shiou-Ling、Omori Hiroko、Zhou Yi、Lin Yee-Shin、Liu Ching-Chuan、Wu Jiunn-Jong、Noda Takeshi
- Journal Title
  
  mBio
  
  Volume: 13 Issue: 4
- DOI
  10.1128/mbio.01233-22
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15789
[Journal Article] Quercetin in Tartary Buckwheat Induces Autophagy against Protein Aggregations2021
- Author(s)
  Sumiko Ikari, Qiang Yang, Shiou-Ling Lu, Yuancai Liu, Feike Hao, Guoqiang Tong, Shiguang Lu and Takeshi Noda
- Journal Title
  
  Antioxidants
  
  Volume: 10 Issue: 8 Pages: 1217-1217
- DOI
  10.3390/antiox10081217
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15789
[Journal Article] Nicotinamide Increases Intracellular NAD+ Content to Enhance Autophagy-Mediated Group A Streptococcal Clearance in Endothelial Cells.2020
- Author(s)
  Cheng-Lu Hsieh, Shu-Ying Hsieh, Hsuan-Min Huang, Shiou-Ling Lu, Hiroko Omori, Po-Xing Zheng, Yen-Ning Ho, Yi-Lin Cheng, Yee-Shin Lin, Chuan Chiang-Ni, Pei-Jane Tsai, Shu-Ying Wang, Ching-Chuan Liu, Takeshi Noda and Jiunn-Jong Wu.
- Journal Title
  
  Front. Microbiol.
  
  Volume: 11 Pages: 117-117
- DOI
  10.3389/fmicb.2020.00117
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21395
[Journal Article] Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy.2019
- Author(s)
  Yi-Lin Cheng, Chih-Feng Kuo, Shiou-Ling Lu, Hiroko Omori, Ya-Na Wu, Cheng-Lu Hsieh, Takeshi Noda, Shang-Rung Wu, Robert Anderson, Chiou-Feng Lin, Chia-Ling Chen, Jiunn-Jong Wu, Yee-Shin Lin.
- Journal Title
  
  mBio
  
  Volume: 10 Issue: 5
- DOI
  10.1128/mbio.02148-19
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21395
[Journal Article] 血管内皮細胞中で細菌が増殖するメカニズム2018
- Author(s)
  川端剛、 Shiou-Ling Lu, 吉森保
- Journal Title
  
  月刊臨床免疫・アレルギー科
  
  Volume: 70 Pages: 532-536
- Data Source
  KAKENHI-PROJECT-19K21395
[Presentation] How Streptococcus pyogenes is (or is not) targeted by autophagy in blood vessel endothelial cells.2023
- Author(s)
  Shiou-Ling Lu
- Organizer
  第96回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20K15789
[Presentation] Mitochondrial autophagy is carried out by microautophagy in macrophages2023
- Author(s)
  Lu Shiou-Ling
- Organizer
  第15 回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-20K15789
[Presentation] Rab32 and Rab38 maintain bone homeostasis by regulating intracellular traffic in osteoclast2023
- Author(s)
  Lu Shiou-Ling
- Organizer
  第９６回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K15789
[Presentation] Mitochondrial autophagy is carried out by microautophagy in macrophages.2023
- Author(s)
  Lu Shiou-Ling
- Organizer
  第75回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-20K15789
[Presentation] Mitochondrial autophagy is carried out by microautophagy in macrophages.2022
- Author(s)
  Shiou-Ling Lu
- Organizer
  The 10th International Symposium on Autophagy.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15789
[Presentation] VEGF-mediated augmentation of autophagic and lysosomal activity in endothelial cells defends against intracellular Streptococcus pyogenes.2022
- Author(s)
  Shiou-Ling Lu
- Organizer
  第20回あわじ感染と免疫国際フォーラム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15789
[Presentation] Study of Rab32/Rab38-positive lysosome- related-organelle involved in GAS clearance in macrophage.2022
- Author(s)
  Shiou-Ling Lu
- Organizer
  EMBO | EMBL Symposium: Innate immunity in host-pathogen interactions.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15789
[Presentation] Rab32とRab38は酸加水分解酵素とV-ATPaseの細胞内輸送を制御することにより破骨細胞の機能を促進する2022
- Author(s)
  Lu Shiou-Ling
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K15789
[Presentation] VEGF-mediated augmentation of autophagic and lysosomal activity in endothelial cells determines the severity of Streptococcus pyogenes infection.2021
- Author(s)
  Lu Shiou-Ling
- Organizer
  WIA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15789
[Presentation] VEGFに依存した血管内皮細胞における抗菌作用機序の解明2019
- Author(s)
  Shiou-Ling Lu, 大森弘子, Chao-Ping Liao, Yee-Shin Lin, Ching-Chuan Liu, 野田健司
- Organizer
  第12回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-19K21395
[Presentation] VEGF activates endo-lysosomal activity through mTORC1-TFEB pathway that suppresses Group A streptococcus infection in endothelial cells.2019
- Author(s)
  Shiou-Ling Lu, Hiroko Omori, Chao-Ping Liao, Yee-Shin Lin, Ching-Chuan Liu, Takeshi Noda.
- Organizer
  8th International Symposium on Autophagy (ISA), Taipei, Taiwan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21395
[Presentation] The mechanism of VEGF-mediated antimicrobial effects for endothelial cell defense against GAS infection.2019
- Author(s)
  Shiou-Ling Lu, Hiroko Omori, Chao-Ping Liao, Yee-Shin Lin, Ching-Chuan Liu, Takeshi Noda.
- Organizer
  International Symposium of Infectious Disease, Tainan, Taiwan.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21395
[Presentation] 化膿レンサ球菌感染におけるVEGFに依存した抗菌作用の解明2019
- Author(s)
  Shiou-Ling Lu, Hiroko Omori, Chao-Ping Liao, Yee-Shin Lin, Ching-Chuan Liu, Takeshi NODA
- Organizer
  日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K21395
[Presentation] Study the mechanism of VEGF-TFEB mediated antimicrobial effects for endothelial cell defense against GAS infection.2018
- Author(s)
  Shiou-Ling Lu
- Organizer
  第11回オートファジー研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K21395
[Presentation] Study the mechanism of VEGF-TFEB mediated antimicrobial effects for endothelial cell defense against GAS infection.2018
- Author(s)
  Shiou-Ling Lu
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K21395

1. 孫戈虹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 田端桂介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Lu Shiou-Ling ＬＵ ＳＨＩＯＵＬＩＮＧ

LU SHIOULING ル シヨオリン

Research Projects

Research Products

Co-Researchers

Rab32-LROによるマクロファージ殺菌機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study the mechanism how Rab32/Rab38 positive lysosome related organelle is involved in bacteria suppression through macroautophagy and microautophagy in macrophage and mouse infectious model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study the antimicrobial activity of VEGF-TFEB for endothelial cells defense against group A streptococcus infection.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Rab32 and Rab38 maintain bone homeostasis by regulating intracellular traffic in osteoclasts2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Characterization of Rab32- and Rab38-positive lysosome-related organelles in osteoclasts and macrophages.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 血管内皮細胞増殖因子の新たな役割：殺菌作業増強効果の発見2023

Author(s)

Journal Title

Data Source

[Journal Article] Opposing roles of RUBCN isoforms in autophagy and memory B cell generation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] オートファジーは健康寿命に寄与するか？2022

Author(s)

Journal Title

Data Source

[Journal Article] VEGF (vascular endothelial growth factor) provides antimicrobial effects via autophagy and lysosomal empowerment in endothelial cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quercetin in Tartary Buckwheat Induces Autophagy against Protein Aggregations2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nicotinamide Increases Intracellular NAD+ Content to Enhance Autophagy-Mediated Group A Streptococcal Clearance in Endothelial Cells.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Group A Streptococcus Induces LAPosomes via SLO/β1 Integrin/NOX2/ROS Pathway in Endothelial Cells That Are Ineffective in Bacterial Killing and Suppress Xenophagy.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 血管内皮細胞中で細菌が増殖するメカニズム2018

Author(s)

Journal Title

Data Source

[Presentation] How Streptococcus pyogenes is (or is not) targeted by autophagy in blood vessel endothelial cells.2023

Author(s)

Organizer

Lu Shiou-Ling ＬＵＳＨＩＯＵＬＩＮＧ

LU SHIOULING ルシヨオリン