higuchi tomoaki 樋口智昭

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Tomoaki Higuchi 樋口智昭

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Researcher Number	80836966
Other IDs
Affiliation (Current)	2025: 東京女子医科大学, 医学部, 寄附部門講師
Affiliation (based on the past Project Information) *help	2023: 東京女子医科大学, 医学部, 寄附部門講師 2021 – 2022: 東京女子医科大学, 医学部, 特任講師 2020: 東京女子医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related
Keywords	Principal Investigator 全身性強皮症 / 線維化 / 強皮症 / PDE阻害薬

Research Projects
(2 results)
Research Products
(13 results)

強皮症線維化病態における疾患特異的PDEサブタイプの探索Principal Investigator
- Principal Investigator
  
  樋口智昭
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Tokyo Women's Medical University
Elucidation of the pathogenesis of systemic sclerosis and development of novel therapeutic strategy focusing on PDEPrincipal Investigator
- Principal Investigator
  
  Tomoaki Higuchi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Tokyo Women's Medical University

All 2023 2022 2021 2020

All Journal Article Presentation Book

[Book] EUSTARデータベースからみた強皮症における進行性間質性肺疾患2022
- Author(s)
  樋口智昭, 川口鎮司
- Total Pages
  5
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-20K17456
[Book] 創薬研究者・アカデミア研究者が知っておくべき最新の免疫学とその応用技術2021
- Author(s)
  樋口智昭, 川口鎮司
- Total Pages
  6
- Publisher
  技術情報協会
- Data Source
  KAKENHI-PROJECT-20K17456
[Book] 日本臨床別冊(呼吸器症候群II)2021
- Author(s)
  樋口智昭, 川口鎮司
- Total Pages
  5
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-20K17456
[Book] 日本臨床別冊(呼吸器症候群II)2021
- Author(s)
  川口鎮司, 樋口智昭
- Total Pages
  6
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-20K17456
[Journal Article] Antifibrotic effect of apremilast in systemic sclerosis dermal fibroblasts and bleomycin-induced mouse model2023
- Author(s)
  Higuchi Tomoaki、Takagi Kae、Tochimoto Akiko、Ichimura Yuki、Hirose Hikaru、Sawada Tatsuo、Shibata Noriyuki、Harigai Masayoshi、Kawaguchi Yasushi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 19378-19378
- DOI
  10.1038/s41598-023-46737-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17456
[Journal Article] Association of elevated serum carbohydrate antigen 19‐9 levels with extensive interstitial lung disease in patients with systemic sclerosis: A cross‐sectional study2023
- Author(s)
  Hirose Hikaru、Higuchi Tomoaki、Takagi Kae、Tochimoto Akiko、Ichimura Yuki、Katsumata Yasuhiro、Harigai Masayoshi、Kawaguchi Yasushi
- Journal Title
  
  International Journal of Rheumatic Diseases
  
  Volume: 27 Issue: 1
- DOI
  10.1111/1756-185x.14978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17456
[Journal Article] Impact of concomitant chronic kidney disease on hospitalised infections and remission in patients with rheumatoid arthritis: results from the IORRA cohort2021
- Author(s)
  Higuchi Tomoaki、Tanaka Eiichi、Inoue Eisuke、Abe Mai、Saka Kumiko、Sugano Eri、Sugitani Naohiro、Higuchi Yoko、Ochiai Moeko、Yamaguchi Rei、Sugimoto Naoki、Ikari Katsunori、Yamanaka Hisashi、Harigai Masayoshi
- Journal Title
  
  Modern Rheumatology
  
  Volume: - Issue: 5 Pages: 875-884
- DOI
  10.1093/mr/roab082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17456
[Journal Article] Characteristics of Japanese patients with systemic sclerosis complicated with calcinosis2021
- Author(s)
  Takagi Kae、Kawamoto Manabu、Higuchi Tomoaki、Tochimoto Akiko、Hirose Hikaru、Harigai Masayoshi、Kawaguchi Yasushi
- Journal Title
  
  International Journal of Rheumatic Diseases
  
  Volume: 803 Issue: 6 Pages: 808-808
- DOI
  10.1111/1756-185x.14121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17456
[Journal Article] Single nucleotide polymorphisms of the HIF1A gene are associated with susceptibility to pulmonary arterial hypertension in systemic sclerosis and contribute to SSc‐PAH disease severity2020
- Author(s)
  Takagi Kae、Kawamoto Manabu、Higuchi Tomoaki、Tochimoto Akiko、Harigai Masayoshi、Kawaguchi Yasushi
- Journal Title
  
  International Journal of Rheumatic Diseases
  
  Volume: 23 Issue: 5 Pages: 674-680
- DOI
  10.1111/1756-185x.13822
- Data Source
  KAKENHI-PROJECT-20K17456
[Presentation] FOXM1 regulates fibrotic activity of skin fibroblasts derived from patients with systemic sclerosis2022
- Author(s)
  Tomoaki Higuchi, Yasushi Kawaguchi
- Organizer
  The 51st Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-20K17456
[Presentation] 日本人男性全身性強皮症(Systemic sclerosis:SSc)の特徴2021
- Author(s)
  Takagi Kae, Kawaguchi Yasushi, Higuchi Tomoaki, Okamoto akiko, Fukasawa Chikako, Harigai Masayoshi
- Organizer
  第65回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K17456
[Presentation] Apremilast attenuates the progression of bleomycin-induced skin fibrosis in mice2020
- Author(s)
  Tomoaki Higuchi, Kae Takagi, Akiko Tochimoto, Yasuhiro Katsumata, Masayoshi Harigai, Yasushi Kawaguchi
- Organizer
  第64回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-20K17456
[Presentation] 2-carba-cPA ameliorates experimental dermal fibrosis by suppressing the activation of fibroblasts and immune cells2020
- Author(s)
  Tomoaki Higuchi, Kae Takagi, Akiko Tochimoto, Takanari Norose, Ikuko Masuda, Tatsuo Sawada, Noriyuki Shibata, Toshiro Morohoshi, Masayoshi Harigai, Yasushi Kawaguchi
- Organizer
  6th SSc World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17456

higuchi tomoaki 樋口 智昭

Tomoaki Higuchi 樋口 智昭

Research Projects

Research Products

強皮症線維化病態における疾患特異的PDEサブタイプの探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathogenesis of systemic sclerosis and development of novel therapeutic strategy focusing on PDEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] EUSTARデータベースからみた強皮症における進行性間質性肺疾患2022

Author(s)

Total Pages

Publisher

Data Source

[Book] 創薬研究者・アカデミア研究者が知っておくべき最新の免疫学とその応用技術2021

Author(s)

Total Pages

Publisher

Data Source

[Book] 日本臨床 別冊(呼吸器症候群II)2021

Author(s)

Total Pages

Publisher

Data Source

[Book] 日本臨床 別冊(呼吸器症候群II)2021

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Antifibrotic effect of apremilast in systemic sclerosis dermal fibroblasts and bleomycin-induced mouse model2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association of elevated serum carbohydrate antigen 19‐9 levels with extensive interstitial lung disease in patients with systemic sclerosis: A cross‐sectional study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of concomitant chronic kidney disease on hospitalised infections and remission in patients with rheumatoid arthritis: results from the IORRA cohort2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characteristics of Japanese patients with systemic sclerosis complicated with calcinosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single nucleotide polymorphisms of the HIF1A gene are associated with susceptibility to pulmonary arterial hypertension in systemic sclerosis and contribute to SSc‐PAH disease severity2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] FOXM1 regulates fibrotic activity of skin fibroblasts derived from patients with systemic sclerosis2022

Author(s)

Organizer

Data Source

[Presentation] 日本人男性全身性強皮症(Systemic sclerosis:SSc)の特徴2021

Author(s)

Organizer

Data Source

[Presentation] Apremilast attenuates the progression of bleomycin-induced skin fibrosis in mice2020

Author(s)

Organizer

Data Source

[Presentation] 2-carba-cPA ameliorates experimental dermal fibrosis by suppressing the activation of fibroblasts and immune cells2020

Author(s)

Organizer

Data Source

higuchi tomoaki 樋口智昭

Tomoaki Higuchi 樋口智昭

[Book] 日本臨床別冊(呼吸器症候群II)2021

[Book] 日本臨床別冊(呼吸器症候群II)2021