Kawashima Naomi 川島直実

Researcher Number	80844844
Affiliation (Current)	2023: 名古屋大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2019 – 2021: 名古屋大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator 0901:Oncology and related fields / Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator 急性骨髄性白血病 / CBF-AML / 好中球エラスターゼ / セリンプロテアーゼ / PRTN3 / 急性白血病

セリンプロテアーゼPRTN3を介したCBF-AMLの発症・進展機序の解明Principal Investigator
- Principal Investigator
  
  川島直実
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Nagoya University
Identification of molecular mechanisms of neutrophil elastase in relapsed/refractory acute myeloid leukemia for developing novel therapiesPrincipal Investigator
- Principal Investigator
  
  Kawashima Naomi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Nagoya University

All 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Comparison of clonal architecture between primary and immunodeficient mouse-engrafted acute myeloid leukemia cells2022
- Author(s)
  Kawashima Naomi、Ishikawa Yuichi、Kim Jeong Hui、Ushijima Yoko、Akashi Akimi、Yamaguchi Yohei、Hattori Hikaru、Nakashima Marie、Ikeno Seara、Kihara Rika、Nishiyama Takahiro、Morishita Takanobu、Watamoto Koichi、Ozawa Yukiyasu、Kitamura Kunio、Kiyoi Hitoshi
- Journal Title
  
  Nature Communications
  
  Volume: 13 Pages: 1-11
- DOI
  10.1038/s41467-022-29304-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08810, KAKENHI-PROJECT-21K16242
[Journal Article] FLT3 inhibitors in the treatment of <i>FLT3</i>-mutated acute myeloid leukemia2021
- Author(s)
  川島直実
- Journal Title
  
  Jpn. J. Clin. Hematol.
  
  Volume: 62 Issue: 8 Pages: 954-966
- DOI
  10.11406/rinketsu.62.954
- NAID
  130008085968
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-21K16242
[Journal Article] Allogeneic hematopoietic stem cell transplantation at the first remission for younger adults with FLT3 ‐internal tandem duplication AML: The JALSG AML209‐FLT3‐SCT study2020
- Author(s)
  Kawashima N, Ishikawa Y, Atsuta Y, Sawa M, Ozawa Y, Hayashi M, Kohno A, Tomita A, Maeda T, Sakaida E, Usuki K, Hagihara M, Kanamori H, Matsuoka H, Kobayashi M, Asou N, Ohtake S, Matsumura I, Miyazaki Y, Naoe T, Kiyoi H
- Journal Title
  
  Cancer Science
  
  Volume: 111 Pages: 2472-2481
- DOI
  10.1111/cas.14448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23912
[Journal Article] Day 0 bone marrow pathology of allogeneic hematopoietic stem cell transplantation is a novel prognostic factor in myeloid malignancies2020
- Author(s)
  Sato Takahiko、Kawashima Naomi、Ito Masafumi、Atsuta Yoshiko、Kagaya Yusuke、Seto Aika、Morishita Takanobu 、Fukushima Nobuaki、Ozawa Yukiyasu、Miyamura Koichi
- Journal Title
  
  BLOOD CELL THERAPY / The official journal of APBMT
  
  Volume: 3 Pages: 84-91
- DOI
  10.31547/bct-2020-007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23912
[Journal Article] Prospective evaluation of prognostic impact of KIT mutations on acute myeloid leukemia with RUNX1-RUNX1T1 and CBFB-MYH112020
- Author(s)
  Ishikawa Y、Kawashima N、Atsuta Y、Sugiura I、Sawa M、Dobashi N、Yokoyama H、Doki N、Tomita A、Kiguchi T、Koh S、Kanamori H、Iriyama N、Kohno A、Moriuchi Y、Asada N、Hirano D、Togitani K、Sakura T、Hagihara M、Tomikawa T、Yokoyama Y、Asou N、Ohtake S、Matsumura I、Miyazaki Y、Naoe T、Kiyoi H
- Journal Title
  
  Blood Advances
  
  Volume: 4 Pages: 66-75
- DOI
  10.1182/bloodadvances.2019000709
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23912, KAKENHI-PROJECT-17K09921
[Journal Article] FLT3 mutations in acute myeloid leukemia: Therapeutic paradigm beyond inhibitor development2019
- Author(s)
  Kiyoi Hitoshi、Kawashima Naomi、Ishikawa Yuichi
- Journal Title
  
  Cancer Science
  
  Volume: 111 Pages: 312-322
- DOI
  10.1111/cas.14274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23912, KAKENHI-PROJECT-17K09921
[Presentation] FLT3 inhibitors: current progress and underlying drug resistance2021
- Author(s)
  Naomi Kawashima
- Organizer
  The JSH International Symposium 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16242
[Presentation] FLT3変異陽性AMLに対する治療戦略2021
- Author(s)
  川島直実
- Organizer
  第83回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K16242
[Presentation] Upregulation of adhesion molecules associates with PDX-specific clonal expansion and R/R AML2020
- Author(s)
  川島直実、石川裕一、金貞姫、木原里香、西山誉大、後藤辰徳、森下喬允、中島麻梨絵、牛島洋子、池野世新、綿本浩一、北村邦朗、小澤幸泰、清井仁
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K23912
[Presentation] FLT3-ITD変異陽性急性骨髄性白血病患者におけるGilteritinib治療感受性と白血病クローン進化の解析2020
- Author(s)
  川島直実, 石川裕一, 金貞姫, 後藤辰徳, 西山誉大, 木原里香, 綿本浩一, 小澤幸泰, 北村邦朗, 清井仁
- Organizer
  第117回日本内科学会講演会
- Data Source
  KAKENHI-PROJECT-19K23912
[Presentation] FLT3-ITD変異陽性AMLに対する第一寛解期での同種造血幹細胞移植：JALSG AML209-FLT3-SCT試験結果2019
- Author(s)
  川島直実, 石川裕一, 熱田由子, 澤正史, 小澤幸泰, 林正樹, 河野彰夫, 冨田章裕, 前田智也, 堺田惠美子, 臼杵憲祐, 萩原真紀, 金森平和, 松岡広, 小林美希, 麻生範雄, 大竹茂樹, 松村到, 宮﨑泰司, 直江知樹, 清井仁
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K23912
[Presentation] Prospective Evaluation of Allogeneic HSCT at the First Remission for Younger Adults with FLT3 -ITD Positive Acute Myeloid Leukemia: The JALSG AML209-FLT3-SCT Study2019
- Author(s)
  Kawashima N, Ishikawa Y, Atsuta Y, Sawa M, Ozawa Y, Hayashi M, Kohno A, Tomita A, Maeda T, Sakaida E, Usuki K, Hagihara M, Kanamori H, Matsuoka H, Kobayashi M, Asou N, Ohtake S, Matsumura I, Miyazaki Y, Naoe T, Kiyoi H
- Organizer
  60th ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23912

1. 石川裕一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 清井仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Kawashima Naomi 川島 直実

Research Projects

Research Products

Co-Researchers

セリンプロテアーゼPRTN3を介したCBF-AMLの発症・進展機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of molecular mechanisms of neutrophil elastase in relapsed/refractory acute myeloid leukemia for developing novel therapiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Comparison of clonal architecture between primary and immunodeficient mouse-engrafted acute myeloid leukemia cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] FLT3 inhibitors in the treatment of <i>FLT3</i>-mutated acute myeloid leukemia2021

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Allogeneic hematopoietic stem cell transplantation at the first remission for younger adults with FLT3 ‐internal tandem duplication AML: The JALSG AML209‐FLT3‐SCT study2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Day 0 bone marrow pathology of allogeneic hematopoietic stem cell transplantation is a novel prognostic factor in myeloid malignancies2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prospective evaluation of prognostic impact of KIT mutations on acute myeloid leukemia with RUNX1-RUNX1T1 and CBFB-MYH112020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] FLT3 mutations in acute myeloid leukemia: Therapeutic paradigm beyond inhibitor development2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] FLT3 inhibitors: current progress and underlying drug resistance2021

Author(s)

Organizer

Data Source

[Presentation] FLT3変異陽性AMLに対する治療戦略2021

Author(s)

Organizer

Data Source

[Presentation] Upregulation of adhesion molecules associates with PDX-specific clonal expansion and R/R AML2020

Author(s)

Organizer

Data Source

[Presentation] FLT3-ITD変異陽性急性骨髄性白血病患者におけるGilteritinib治療感受性と白血病クローン進化の解析2020

Author(s)

Organizer

Data Source

[Presentation] FLT3-ITD変異陽性AMLに対する第一寛解期での同種造血幹細胞移植：JALSG AML209-FLT3-SCT試験結果2019

Author(s)

Organizer

Data Source

[Presentation] Prospective Evaluation of Allogeneic HSCT at the First Remission for Younger Adults with FLT3 -ITD Positive Acute Myeloid Leukemia: The JALSG AML209-FLT3-SCT Study2019

Author(s)

Organizer

Data Source

Kawashima Naomi 川島直実