Tsurudome Yuya 鶴留優也

Researcher Number	80846254
Other IDs	https://orcid.org/0000-0002-6454-9778
Affiliation (Current)	2025: 山陽小野田市立山口東京理科大学, 薬学部, 助教
Affiliation (based on the past Project Information) *help	2024: 山陽小野田市立山口東京理科大学, 薬学部, 助教 2019 – 2022: 山陽小野田市立山口東京理科大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 59040:Nutrition science and health science-related / 0802:Biomedical structure and function and related fields
Keywords	Principal Investigator 膜タンパク質 / 足場タンパク質 / 細胞膜タンパク質 / 概日リズム / 時間生物学 / BBB / 糖尿病 / 脂肪酸 / 栄養学 / トランスポーター … More / 脂質 / 食生活 / 日内変動 / 細胞膜発現 / miRNA / 脂質異常症 / 脂質トランスポーター / 代謝性疾患 / 細胞生物学 / 薬物動態学 Less

Research Projects
(3 results)
Research Products
(11 results)

Mechanism of deposition of metabolic effluents by increased endocytosis receptor expression in brain microvessels in diabetes mellitus.Principal Investigator
- Principal Investigator
  
  鶴留優也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Tokyo University of Science, Yamaguchi
Rhythmic disruption of membrane protein expression and fatty acid accumulation produced by abnormal feeding timingPrincipal Investigator
- Principal Investigator
  
  Tsurudome Yuya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo University of Science, Yamaguchi
Evaluation of circadian scaffold protein for diurnal localization of membrane transporterPrincipal Investigator
- Principal Investigator
  
  Tsurudome Yuya
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0802:Biomedical structure and function and related fields
- Research Institution
  Tokyo University of Science, Yamaguchi

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] The scaffold protein PDZK1 governs diurnal localization of CNT2 on the plasma membrane in mouse intestinal epithelial cells2023
- Author(s)
  Jaballah Nour、Tsurudome Yuya、Murakami Chiho、Matsunaga Naoya、Ushijima Kentaro、Koyanagi Satoru、Ohdo Shigehiro
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: - Issue: 2 Pages: 193-201
- DOI
  10.1093/jb/mvad035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K19715
[Journal Article] Decreased ZO1 expression causes loss of time-dependent tight junction function in the liver of ob/ob mice2022
- Author(s)
  Tsurudome Yuya、Morita Nao、Horiguchi Michiko、Ushijima Kentaro
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 49 Issue: 12 Pages: 11881-11890
- DOI
  10.1007/s11033-022-07940-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K19715
[Journal Article] Potential mechanism of hepatic lipid accumulation during a long-term rest phase restricted feeding in mice2022
- Author(s)
  Tsurudome Yuya、Akamine Takahiro、Horiguchi Michiko、Wada Yukiyo、Fujimura Akio、Ushijima Kentaro
- Journal Title
  
  Chronobiology International
  
  Volume: 39 Issue: 8 Pages: 1132-1143
- DOI
  10.1080/07420528.2022.2077746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K19715
[Journal Article] 足場タンパク質が形成するトランスポーターの細胞膜局在の日内変動2021
- Author(s)
  鶴留優也
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K23832
[Journal Article] 足場タンパク質が形成するトランスポーターの細胞膜局在の日内変動2021
- Author(s)
  鶴留優也
- Journal Title
  
  Drug metabolism and pharmacokinetics
  
  Volume: 36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K19715
[Presentation] 高血糖時における肝細胞の細胞接着機能不全の要因解明2022
- Author(s)
  鶴留優也、堀口道子、牛島健太郎
- Organizer
  第43回日本臨床薬理学会学術総会
- Data Source
  KAKENHI-PROJECT-20K19715
[Presentation] 細胞膜タンパク質の発現リズムが形成する肝脂肪酸取り込みリズム2022
- Author(s)
  鶴留優也
- Organizer
  第 16 回次世代を担う若手医療薬科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K19715
[Presentation] 糖尿病モデルマウスの肝臓におけるタイトジャンクション機能変容のメカニズム解析2021
- Author(s)
  鶴留優也、森田菜央、堀口道子、牛島健太郎
- Organizer
  日本薬学会　第１４２年会
- Data Source
  KAKENHI-PROJECT-20K19715
[Presentation] 不適切な食事タイミングが引き起こす肝臓脂質異常症の解析2021
- Author(s)
  鶴留優也、堀口道子、藤村昭夫、牛島健太郎
- Organizer
  日本薬学会　第１４１年会
- Data Source
  KAKENHI-PROJECT-20K19715
[Presentation] 不適切な食事タイミングが引き起こす肝臓内脂質蓄積に、マイクロ RNA発現異常が関与する2021
- Author(s)
  牛島健太郎、鶴留優也、和田由喜世、堀口道子、藤村昭夫
- Organizer
  日本薬学会　第１４２年会
- Data Source
  KAKENHI-PROJECT-20K19715
[Presentation] 不適切な食事タイミングが引き起こす肝臓脂質異常症の解析2020
- Author(s)
  鶴留優也、堀口道子、藤村昭夫、牛島健太郎
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K23832

Tsurudome Yuya 鶴留 優也

Research Projects

Research Products

Mechanism of deposition of metabolic effluents by increased endocytosis receptor expression in brain microvessels in diabetes mellitus.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Rhythmic disruption of membrane protein expression and fatty acid accumulation produced by abnormal feeding timingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of circadian scaffold protein for diurnal localization of membrane transporterPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The scaffold protein PDZK1 governs diurnal localization of CNT2 on the plasma membrane in mouse intestinal epithelial cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Decreased ZO1 expression causes loss of time-dependent tight junction function in the liver of ob/ob mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Potential mechanism of hepatic lipid accumulation during a long-term rest phase restricted feeding in mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 足場タンパク質が形成するトランスポーターの細胞膜局在の日内変動2021

Author(s)

Journal Title

Data Source

[Journal Article] 足場タンパク質が形成するトランスポーターの細胞膜局在の日内変動2021

Author(s)

Journal Title

Data Source

[Presentation] 高血糖時における肝細胞の細胞接着機能不全の要因解明2022

Author(s)

Organizer

Data Source

[Presentation] 細胞膜タンパク質の発現リズムが形成する肝脂肪酸取り込みリズム2022

Author(s)

Organizer

Data Source

[Presentation] 糖尿病モデルマウスの肝臓におけるタイトジャンクション機能変容のメ カニズム解析2021

Author(s)

Organizer

Data Source

[Presentation] 不適切な食事タイミングが引き起こす肝臓脂質異常症の解析2021

Author(s)

Organizer

Data Source

[Presentation] 不適切な食事タイミングが引き起こす肝臓内脂質蓄積に、マイクロ RNA発現異常が関与する2021

Author(s)

Organizer

Data Source

[Presentation] 不適切な食事タイミングが引き起こす肝臓脂質異常症の解析2020

Author(s)

Organizer

Data Source

Tsurudome Yuya 鶴留優也

[Presentation] 糖尿病モデルマウスの肝臓におけるタイトジャンクション機能変容のメカニズム解析2021