OKADOME KAZUO 岡留一雄

Researcher Number	80867200
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2023: 熊本大学, 大学院生命科学研究部(医), 特定研究員
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator 消化器癌 / 癌関連線維芽細胞 / 腸内細菌叢 / Fusobacterium / 腫瘍免疫 / 腸内細菌 / CAFs(癌関連繊維芽細胞) / Esophageal cancer / Fusobacterium nucleatum / 腫瘍関連マクロファージ … More / PD-L2 / PD-L1 / 免疫チェックポイント / CCL8 Less

Analyzing the mechanism of the effects of Fusobacterium cooperated with cancer-associated fibroblasts on gastrointestinal cancersPrincipal Investigator
- Principal Investigator
  
  岡留一雄
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kumamoto University
Analyzing the mechanism of CCL8 induce immune checkpoint molecules including PD-L2Principal Investigator
- Principal Investigator
  
  OKADOME KAZUO
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University

All 2024 2023 2022 2021

All Journal Article

[Journal Article] Enrichment of Bacteroides fragilis and enterotoxigenic Bacteroides fragilis in CpG island methylator phenotype-high colorectal carcinoma2024
- Author(s)
  Takashima Yasutoshi、Kawamura Hidetaka、Okadome Kazuo、Ugai Satoko、Haruki Koichiro、Arima Kota、Mima Kosuke、Akimoto Naohiko、Nowak Jonathan A.、Giannakis Marios、Garrett Wendy S.、Sears Cynthia L.、Song Mingyang、Ugai Tomotaka、Ogino Shuji
- Journal Title
  
  Clinical Microbiology and Infection
  
  Volume: 30 Issue: 5 Pages: 630-636
- DOI
  10.1016/j.cmi.2024.01.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15980, KAKENHI-PROJECT-23K15435, KAKENHI-PROJECT-21K08686, KAKENHI-PROJECT-21K08805
[Journal Article] Intratumour Fusobacterium nucleatum and immune response to oesophageal cancer2023
- Author(s)
  Kosumi Keisuke、Baba Yoshifumi、Yamamura Kensuke、Nomoto Daichi、Okadome Kazuo、Yagi Taisuke、Toihata Tasuku、Kiyozumi Yuki、Harada Kazuto、Eto Kojiro、Sawayama Hiroshi、Ishimoto Takatsugu、Iwatsuki Masaaki、Iwagami Shiro、Miyamoto Yuji、Yoshida Naoya、Watanabe Masayuki、Baba Hideo
- Journal Title
  
  British Journal of Cancer
  
  Volume: 128 Issue: 6 Pages: 1155-1165
- DOI
  10.1038/s41416-022-02112-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08687, KAKENHI-PROJECT-20H03755, KAKENHI-PROJECT-21K16452, KAKENHI-PROJECT-23K24408, KAKENHI-PROJECT-23K15435, KAKENHI-PROJECT-22K08851, KAKENHI-PROJECT-21KK0153
[Journal Article] Inverse relationship between Fusobacterium nucleatum amount and tumor CD274 (PD‐L1) expression in colorectal carcinoma2023
- Author(s)
  Ugai T, Shimizu T, Kawamura H, Ugai S, Takashima Y, Usui G, Vayrynen JP, Okadome K, Haruki K, Akimoto N, Masugi Y, da Silva A, Mima K, Zhang X, Chan AT, Wang M, Garrett WS, Freeman GJ, Meyerhardt JA, Nowak JA, Song M, Giannakis M, Ogino S
- Journal Title
  
  Clinical & Translational Immunology
  
  Volume: 12 Issue: 8 Pages: 1453-1453
- DOI
  10.1002/cti2.1453
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15980, KAKENHI-PROJECT-23K15435, KAKENHI-PROJECT-21K08805, KAKENHI-PROJECT-20K17210
[Journal Article] Fusobacterium nucleatum promotes esophageal squamous cell carcinoma progression via the NOD1/RIPK2/NF-κB pathway2022
- Author(s)
  Nomoto Daichi、Baba Yoshifumi、Liu Yang、Tsutsuki Hiroyasu、Okadome Kazuo、Harada Kazuto、Ishimoto Takatsugu、Iwatsuki Masaaki、Iwagami Shiro、Miyamoto Yuji、Yoshida Naoya、Watanabe Masayuki、Moroishi Toshiro、Komohara Yoshihiro、Sawa Tomohiro、Baba Hideo
- Journal Title
  
  Cancer Letters
  
  Volume: 530 Pages: 59-67
- DOI
  10.1016/j.canlet.2022.01.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08714, KAKENHI-PROJECT-20H03459, KAKENHI-PROJECT-20H03755, KAKENHI-PROJECT-21K16452, KAKENHI-PROJECT-23K24408
[Journal Article] PD‐L1 and PD‐L2 expression status in relation to chemotherapy in primary and metastatic esophageal squamous cell carcinoma2021
- Author(s)
  Okadome Kazuo、Baba Yoshifumi、Yasuda‐Yoshihara Noriko、Nomoto Daichi、Yagi Taisuke、Toihata Tasuku、Ogawa Katsuhiro、Sawayama Hiroshi、Ishimoto Takatsugu、Iwatsuki Masaaki、Iwagami Shiro、Miyamoto Yuji、Yoshida Naoya、Watanabe Masayuki、Komohara Yoshihiro、Baba Hideo
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 2 Pages: 399-410
- DOI
  10.1111/cas.15198
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16452, KAKENHI-PROJECT-21K16476

1. 馬場祥史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 小澄敬祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 原田和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 秋元直彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 野元大地

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 岩槻政晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OKADOME KAZUO 岡留 一雄

Research Projects

Research Products

Co-Researchers

Analyzing the mechanism of the effects of Fusobacterium cooperated with cancer-associated fibroblasts on gastrointestinal cancersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyzing the mechanism of CCL8 induce immune checkpoint molecules including PD-L2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Enrichment of Bacteroides fragilis and enterotoxigenic Bacteroides fragilis in CpG island methylator phenotype-high colorectal carcinoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intratumour Fusobacterium nucleatum and immune response to oesophageal cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inverse relationship between Fusobacterium nucleatum amount and tumor CD274 (PD‐L1) expression in colorectal carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fusobacterium nucleatum promotes esophageal squamous cell carcinoma progression via the NOD1/RIPK2/NF-κB pathway2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PD‐L1 and PD‐L2 expression status in relation to chemotherapy in primary and metastatic esophageal squamous cell carcinoma2021

Author(s)

Journal Title

DOI

Data Source

OKADOME KAZUO 岡留一雄