Murayama Yuki 村山友樹

Researcher Number	80869248
Affiliation (Current)	2026: 筑波大学, 附属病院, 病院講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 筑波大学, 附属病院, 病院講師 2020 – 2021: 筑波大学, 附属病院, 病院講師
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related
Keywords	Principal Investigator GR / 時計遺伝子 / Nr1D1 / 糖質コルチコイド / Nr1ｄ1 / 糖質ステロイドホルモン / Nr1d1 / グルココルチコイド / 血糖 / 脂質 / 代謝 / ステロイド / グルココルチコイドレセプター

Elucidating molecular mechanisms of circadian rhythm regulation by tethering effect from glucocorticoid receptor.Principal Investigator
- Principal Investigator
  
  Murayama Yuki
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  University of Tsukuba
Elucidating molecular mechanisms of metabolism and circadian rhythm regulation by glucocorticoid receptorPrincipal Investigator
- Principal Investigator
  
  Murayama Yuki
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  University of Tsukuba

All 2024 2023 2021

All Journal Article Presentation

[Journal Article] FoxO transcription factors regulate urea cycle through Ass12024
- Author(s)
  Karkoutly Samia、Takeuchi Yoshinori、Mehrazad Saber Zahra、Ye Chen、Tao Duhan、Aita Yuichi、Murayama Yuki、Shikama Akito、Masuda Yukari、Izumida Yoshihiko、Matsuzaka Takashi、Kawakami Yasushi、Shimano Hitoshi、Yahagi Naoya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 739 Pages: 150594-150594
- DOI
  10.1016/j.bbrc.2024.150594
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-23K15405, KAKENHI-PROJECT-23K24760, KAKENHI-PROJECT-24K02851, KAKENHI-PROJECT-22K11851, KAKENHI-PROJECT-24K14622, KAKENHI-PROJECT-24K22110
[Journal Article] <scp>GR‐KLF15</scp> pathway controls hepatic lipogenesis during fasting2023
- Author(s)
  Takeuchi Y, Murayama Y, Aita Y, Mehrazad Saber Z, Karkoutly S, Tao D, Katabami K, Ye C, Shikama A, Masuda Y, Izumida Y, Miyamoto T, Matsuzaka T, Kawakami Y, Shimano H, Yahagi N.
- Journal Title
  
  The FEBS Journal
  
  Volume: 291 Issue: 2 Pages: 259-271
- DOI
  10.1111/febs.16957
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18444, KAKENHI-PROJECT-23K13900, KAKENHI-PROJECT-23K15405, KAKENHI-PROJECT-22K11851, KAKENHI-PROJECT-22H00474, KAKENHI-PROJECT-23K23562, KAKENHI-PROJECT-23K24760
[Journal Article] FoxO-KLF15 pathway switches the flow of macronutrients under the control of insulin2021
- Author(s)
  Takeuchi Yoshinori、Yahagi Naoya、Aita Yuichi、Mehrazad-Saber Zahra、Ho Man Hei、Huyan Yiren、Murayama Yuki、Shikama Akito、Masuda Yukari、Izumida Yoshihiko、Miyamoto Takafumi、Matsuzaka Takashi、Kawakami Yasushi、Shimano Hitoshi
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 12 Pages: 103446-103446
- DOI
  10.1016/j.isci.2021.103446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-19K20175, KAKENHI-PROJECT-20K17505, KAKENHI-PROJECT-21K19064
[Journal Article] CtBP2 confers protection against oxidative stress through interactions with NRF1 and NRF22021
- Author(s)
  Kainoh Kenta、Takano Ryo、Sekiya Motohiro、Saito Kenji、Sugasawa Takehito、Ma Yang、Murayama Yuki、Sugano Yoko、Osaki Yoshinori、Iwasaki Hitoshi、Takeuchi Yoshinori、Yahagi Naoya、Suzuki Hiroaki、Miyamoto Takafumi、Nakagawa Yoshimi、Matsuzaka Takashi、Shimano Hitoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 562 Pages: 146-153
- DOI
  10.1016/j.bbrc.2021.05.069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-20K17505, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064
[Journal Article] High protein diet-induced metabolic changes are transcriptionally regulated via KLF15-dependent and independent pathways2021
- Author(s)
  Mehrazad Saber Zahra、Takeuchi Yoshinori、Sawada Yoshikazu、Aita Yuichi、Ho Man Hei、Karkoutly Samia、Tao Duhan、Katabami Kyoka、Ye Chen、Murayama Yuki、Shikama Akito、Masuda Yukari、Izumida Yoshihiko、Miyamoto Takafumi、Matsuzaka Takashi、Sugasawa Takehito、Takekoshi Kazuhiro、Kawakami Yasushi、Shimano Hitoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 582 Pages: 35-42
- DOI
  10.1016/j.bbrc.2021.10.027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07272, KAKENHI-PROJECT-19K20175, KAKENHI-PROJECT-20K17505, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-21H03371, KAKENHI-PROJECT-21K19064
[Journal Article] Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition2021
- Author(s)
  Nakagawa Yoshimi、Wang Yunong、Han Song-iee、Okuda Kanako、Oishi Asayo、Yagishita Yuka、Kumagai Kae、Ohno Hiroshi、Osaki Yoshinori、Mizunoe Yuhei、Araki Masaya、Murayama Yuki、Iwasaki Hitoshi、Konishi Morichika、Itoh Nobuyuki、Matsuzaka Takashi、Sone Hirohito、Yamada Nobuhiro、Shimano Hitoshi
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 11 Issue: 4 Pages: 949-971
- DOI
  10.1016/j.jcmgh.2020.11.004
- NAID
  120006939158
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11713, KAKENHI-PROJECT-19K11737, KAKENHI-PROJECT-20K21611, KAKENHI-PROJECT-20K21643, KAKENHI-PROJECT-20K19669, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-20K17505, KAKENHI-PROJECT-18KT0065, KAKENHI-PROJECT-21H04861
[Presentation] GR-KLF15経路は絶食時における肝臓での脂質合成を制御する2024
- Author(s)
  武内謙憲、Mehrazad Saber Zahra、Karkoutly Samia、陶都罕、Ye Chen、犀川理加、會田雄一、村山友樹、志鎌明人、升田紫、泉田欣彦、川上康、島野仁、矢作直也
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K15405
[Presentation] in vivo Ad-luc法とTFEL scan法を用いたニュートリゲノミクスへのアプローチ2023
- Author(s)
  武内謙憲、矢作直也、會田雄一、Mehrazad Saber Zahra、Karkoutly Samia、Tao Duhan、方波見京香、Ye Chen、Wang Xinyu、村山友樹、志鎌明人、升田紫、泉田欣彦、川上康、島野仁
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K15405
[Presentation] 免疫チェックポイント阻害薬使用中に甲状腺中毒症と副腎不全を合併した2症例2021
- Author(s)
  松本なこ, 菅野洋子, 高島佑典, 中島里佳子, 大内奈美, 大澤真理子, 村山友樹, 大崎芳典, 岩崎仁, 関谷元博, 矢作直也, 鈴木浩明, 島野仁
- Organizer
  第94回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K17505
[Presentation] 栄養素(ブドウ糖,アミノ酸,脂質)の代謝と肝疾患と糖尿病　生体イメージングを用いたニュートリゲノミクスへのアプローチ2021
- Author(s)
  武内謙憲, 矢作直也, 會田雄一, 村山友樹, Zahra Mehrazad Saber, 何敏煕, Karkoutly Samia, 陶都罕, 方波見京香, 志鎌明人, 升田紫, 泉田欣彦, 川上康, 島野仁
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K17505
[Presentation] 血中遊離メタネフリン2分画の実臨床での精度の検証2021
- Author(s)
  近藤未来, 村山友樹, 竹越一博, 大内奈美, 松本なこ, 中島里佳子, 大澤真理子, 菅野洋子, 大崎芳典, 岩崎仁, 関谷元博, 矢作直也, 鈴木浩明, 島野仁
- Organizer
  第31回臨床内分泌代謝Update
- Data Source
  KAKENHI-PROJECT-20K17505
[Presentation] 多価不飽和脂肪酸(PUFA)によるSREBP-1特異的な抑制機序の解明2021
- Author(s)
  升田紫, 矢作直也, 武内謙憲, 和田亘弘, 呼延宜人, Zahra Mehrazad Saber, 沢田義一, 村山友樹, 會田雄一, 西真貴子[辰巳], 泉田欣彦, 位高啓史, 片岡一則, 島野仁, 門脇孝, 山内敏正
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K17505
[Presentation] 当院におけるCOVID-19流行による糖尿病患者の血糖コントロールの変動について2021
- Author(s)
  中島里佳子, 岩崎仁, 高島佑典, 大内奈美, 松本なこ, 大澤真理子, 村山友樹, 大崎芳典, 菅野洋子, 関谷元博, 矢作直也, 鈴木浩明, 島野仁
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K17505
[Presentation] 甲状腺機能亢進が疑われたIgMの干渉によるfT3偽高値の一例2021
- Author(s)
  相馬奈生, 村山友樹, 関谷元博, 菊池裕一, 大内奈美, 中島里佳子, 松本なこ, 大澤真理子, 大崎芳典, 菅野洋子, 岩崎仁, 矢作直也, 鈴木浩明, 加藤龍一, 島野仁
- Organizer
  第31回臨床内分泌代謝Update
- Data Source
  KAKENHI-PROJECT-20K17505
[Presentation] 高血糖高浸透圧症候群の経過中に急性動脈閉塞症を発症し、左下肢切断に至った1例2021
- Author(s)
  中島里佳子, 高島佑典, 大崎芳典, 大澤真理子, 村山友樹, 菅野洋子, 岩崎仁, 関谷元博, 矢作直也, 鈴木浩明, 島野仁
- Organizer
  第58回日本糖尿病学会関東甲信越地方会
- Data Source
  KAKENHI-PROJECT-20K17505
[Presentation] Identification of PUFA-responsive domain on SREBP-1 as SCAP-independent C-terminal region.2021
- Author(s)
  Masuda Y, Yahagi N, Takeuchi Y, Aita Y, Murayama Y, Wada N, Huyan Y, Mehrazad Saber Z, Sawada Y, Shikama A, Izumida Y, Shimano H, Yamauchi T
- Organizer
  American Heart Association Scientific Sessions 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17505

1. 武内謙憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
2. 松坂賢

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 中川嘉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 韓松伊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Murayama Yuki 村山 友樹

Research Projects

Research Products

Co-Researchers

Elucidating molecular mechanisms of circadian rhythm regulation by tethering effect from glucocorticoid receptor.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating molecular mechanisms of metabolism and circadian rhythm regulation by glucocorticoid receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] FoxO transcription factors regulate urea cycle through Ass12024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <scp>GR‐KLF15</scp> pathway controls hepatic lipogenesis during fasting2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] FoxO-KLF15 pathway switches the flow of macronutrients under the control of insulin2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CtBP2 confers protection against oxidative stress through interactions with NRF1 and NRF22021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High protein diet-induced metabolic changes are transcriptionally regulated via KLF15-dependent and independent pathways2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enterohepatic Transcription Factor CREB3L3 Protects Atherosclerosis via SREBP Competitive Inhibition2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] GR-KLF15経路は絶食時における肝臓での脂質合成を制御する2024

Author(s)

Organizer

Data Source

[Presentation] in vivo Ad-luc法とTFEL scan法を用いたニュートリゲノミクスへのアプローチ2023

Author(s)

Organizer

Data Source

[Presentation] 免疫チェックポイント阻害薬使用中に甲状腺中毒症と副腎不全を合併した2症例2021

Author(s)

Organizer

Data Source

[Presentation] 栄養素(ブドウ糖,アミノ酸,脂質)の代謝と肝疾患と糖尿病 生体イメージングを用いたニュートリゲノミクスへのアプローチ2021

Author(s)

Organizer

Data Source

[Presentation] 血中遊離メタネフリン2分画の実臨床での精度の検証2021

Author(s)

Organizer

Data Source

[Presentation] 多価不飽和脂肪酸(PUFA)によるSREBP-1特異的な抑制機序の解明2021

Author(s)

Organizer

Data Source

[Presentation] 当院におけるCOVID-19流行による糖尿病患者の血糖コントロールの変動について2021

Author(s)

Organizer

Data Source

[Presentation] 甲状腺機能亢進が疑われたIgMの干渉によるfT3偽高値の一例2021

Author(s)

Organizer

Data Source

[Presentation] 高血糖高浸透圧症候群の経過中に急性動脈閉塞症を発症し、左下肢切断に至った1例2021

Murayama Yuki 村山友樹

[Presentation] 栄養素(ブドウ糖,アミノ酸,脂質)の代謝と肝疾患と糖尿病　生体イメージングを用いたニュートリゲノミクスへのアプローチ2021