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KOYAMA YUU  小山 侑

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Koyama Yu  小山 侑

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Researcher Number 80875691
Other IDs
Affiliation (Current) 2026: 東京歯科大学, 歯学部, 講師
Affiliation (based on the past Project Information) *help 2026: 東京歯科大学, 歯学部, 助教
2020 – 2024: 東京歯科大学, 歯学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 57060:Surgical dentistry-related / 0907:Oral science and related fields
Except Principal Investigator
Basic Section 57060:Surgical dentistry-related
Keywords
Principal Investigator
heterogeneity / CAFs / RUNX3 / 口腔癌 / 炎症性サイトカイン / 癌微小環境 / 癌関連線維芽細胞
Except Principal Investigator
口腔扁平上皮癌 / 唾液腺腫瘍 / 癌内線維芽細胞 … More / PDXマウス / 悪性唾液腺腫瘍 / liquid biopsy / OPMDs / メタボローム解析 / 扁平上皮癌 / 細胞増殖 / メタボローム / バイオマーカー / コリントランスポーター / コリン Less
  • Research Projects

    (5 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (6 People)
  •  癌関連線維芽細胞・癌細胞相互作用の解析による口腔癌進展メカニズムの基盤的な理解Principal Investigator

    • Principal Investigator
      小山 侑
    • Project Period (FY)
      2026 – 2028
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Tokyo Dental College
  •  Establishment of PDX model of malignant salivary gland tumors and investigation of malignant transformation mechanism

    • Principal Investigator
      菅原 圭亮
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Tokyo Dental College
  •  唾液中のcholine transporter-like protein(CTL1)は上皮異形成を反映する

    • Principal Investigator
      片倉 朗
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Tokyo Dental College
  •  口腔癌CAFsサブタイプの同定と腫瘍促進機構の解明Principal Investigator

    • Principal Investigator
      小山 侑
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Tokyo Dental College
  •  Elucidation of the role of RUNX3 in cancer-associated fibroblasts (CAFs)Principal Investigator

    • Principal Investigator
      Koyama Yu
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0907:Oral science and related fields
    • Research Institution
      Tokyo Dental College

All 2024 2023

All Journal Article

  • [Journal Article] Expression of Lymphoid Enhancer-Binding Factor 1 in Cancer-Associated Fibroblasts Mediates Tumor Growth and Transdifferentiation Toward Squamous Cell Carcinoma in Human Breast Cancer2024

    • Author(s)
      Okazaki H, Mezawa Y, Shi Y, Sakimoto M, Wang Z, Takano A, Yokose T, Yamashita T, Miyagi Y, Daigo Y, Katakura A, Yasukawa T, Orimo A
    • Journal Title

      Cancer Medicine

      Volume: 14(3) Issue: 3

    • DOI

      10.1002/cam4.70627

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-21K07127, KAKENHI-PROJECT-23K27506, KAKENHI-PROJECT-22K07215, KAKENHI-PROJECT-24K10363, KAKENHI-PROJECT-22K17217, KAKENHI-PROJECT-23K14603
  • [Journal Article] Pathological examination of factors involved in PD-L1 expression in patients with oral tongue squamous cell carcinoma2024

    • Author(s)
      Yu Koyama, Chiharu Ogawa, Chihiro Kurihara, Nao Hashimoto, Shota Shinagawa, Hiroya Okazaki, Takumi Koyama, Keisuke Sugahara, Akira Katakura
    • Journal Title

      Maxillofacial Plastic Reconstruction Surgery

      Volume: 1 Issue: 1 Pages: 1-7

    • DOI

      10.1186/s40902-024-00441-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K09380, KAKENHI-PROJECT-24K13079
  • [Journal Article] Increased <scp>RUNX3</scp> expression mediates tumor‐promoting ability of human breast cancer‐associated fibroblasts2023

    • Author(s)
      Koyama Yu、Okazaki Hiroya、Shi Yang、Mezawa Yoshihiro、Wang Zixu、Sakimoto Mizuki、Ishizuka Akane、Ito Yasuhiko、Koyama Takumi、Daigo Yataro、Takano Atsushi、Miyagi Yohei、Yokose Tomoyuki、Yamashita Toshinari、Sugahara Keisuke、Hino Okio、Yang Liying、Maruyama Reo、Katakura Akira、Yasukawa Takehiro、Orimo Akira
    • Journal Title

      Cancer Medicine

      Volume: 12 Issue: 17 Pages: 18062-18077

    • DOI

      10.1002/cam4.6421

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K17217, KAKENHI-PROJECT-23K14603, KAKENHI-PROJECT-21K07127, KAKENHI-PROJECT-22K20837, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K27506
  • 1.  片倉 朗 (10233743)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  小山 拓洋 (50906386)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  菅原 圭亮 (10506926)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  醍醐 弥太郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  宮城 洋平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  橘 逸勢
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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