Kimura Takefumi 木村岳史

Researcher Number	80926113
Other IDs
Affiliation (Current)	2026: 信州大学, 学術研究院医学系(医学部附属病院), 講師
Affiliation (based on the past Project Information) *help	2024: 信州大学, 学術研究院医学系(医学部附属病院), 講師 2023: 信州大学, 学術研究院医学系, 講師 2022: 信州大学, 学術研究院医学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / 0902:General internal medicine and related fields
Keywords	Principal Investigator 肝線維化 / B型肝炎 / C型肝炎 / MASLD / 肝癌 / THBS2 / 肝疾患 / 肝臓 / 線維化 / NASH … More / 肝細胞癌 / トロンボスポンジン２ / HCC / HBV / HCV / NAFLD / TSP2 / トロンボスポンジン2 Less

Examining the Hypothesis: Suppression of THBS2 Gene Alleviates Liver FibrosisPrincipal Investigator
- Principal Investigator
  
  木村岳史
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Shinshu University
Elucidation of a Novel Liver Fibrosis Mechanism Mediated by Thrombospondin 2Principal Investigator
- Principal Investigator
  
  Kimura Takefumi
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0902:General internal medicine and related fields
- Research Institution
  Shinshu University

All 2024 2023 2022

All Journal Article Presentation

[Journal Article] Thrombospondin 2 as a Predictive Biomarker for <scp>HCC</scp> in?Hepatitis C Patients: A Longitudinal Study Following <scp>DAA</scp> Therapy2024
- Author(s)
  Iwadare Takanobu、Kimura Takefumi、Sugiura Ayumi、Okumura Taiki、Wakabayashi Shun‐ichi、Kobayashi Hiroyuki、Yamashita Yuki、Yamazaki Tomoo、Joshita Satoru、Tanaka Naoki、Umemura Takeji
- Journal Title
  
  Journal of Viral Hepatitis
  
  Volume: 32 Issue: 4
- DOI
  10.1111/jvh.14025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20884, KAKENHI-PROJECT-24K11087
[Journal Article] Serum Autotaxin Levels Predict Liver-Related Events in Patients With Primary Biliary Cholangitis: A Long-Term Multicenter Observational Study2024
- Author(s)
  Iwadare Takanobu、Kimura Takefumi、Yamashita Yuki、Okumura Taiki、Wakabayashi Shun-ichi、Kobayashi Hiroyuki、Sugiura Ayumi、Yamazaki Tomoo、Shimamoto Satoshi、Igarashi Koji、Joshita Satoru、Umemura Takeji
- Journal Title
  
  Clinical and Translational Gastroenterology
  
  Volume: 15 Issue: 12 Pages: e00779-e00779
- DOI
  10.14309/ctg.0000000000000779
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18561, KAKENHI-PROJECT-22K20884, KAKENHI-PROJECT-24K11087
[Journal Article] Circulating thrombospondin 2 as a predictor of hepatocellular carcinoma in hepatitis B patients undergoing nucleos(t)ide analog therapy2024
- Author(s)
  Okumura Taiki、Kimura Takefumi、Ichikawa Yuki、Iwadare Takanobu、Wakabayashi Shun-ichi、Kobayashi Hiroyuki、Yamashita Yuki、Uchida Takuro、Pydi Sai P.、Tanaka Naoki、Umemura Takeji
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 25584-25584
- DOI
  10.1038/s41598-024-76532-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20884, KAKENHI-PROJECT-24K11087, KAKENHI-PROJECT-24K18920
[Journal Article] Thrombospondin 2 is a key determinant of fibrogenesis in non‐alcoholic fatty liver disease2023
- Author(s)
  Kimura Takefumi、Iwadare Takanobu、Wakabayashi Shun‐ichi、Kuldeep Seema、Nakajima Tomoyuki、Yamazaki Tomoo、Aomura Daiki、Zafar Hamim、Iwaya Mai、Joshita Satoru、Uehara Takeshi、Pydi Sai P.、Tanaka Naoki、Umemura Takeji
- Journal Title
  
  Liver International
  
  Volume: 44 Issue: 2 Pages: 483-496
- DOI
  10.1111/liv.15792
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20884, KAKENHI-PROJECT-23K18561
[Journal Article] Circulating thrombospondin 2 levels reflect fibrosis severity and disease activity in HCV-infected patients2022
- Author(s)
  Iwadare Takanobu、Kimura Takefumi、Tanaka Naoki、Yamazaki Tomoo、Wakabayashi Shun-ichi、Okumura Taiki、Kobayashi Hiroyuki、Yamashita Yuki、Pydi Sai P.、Nakajima Tomoyuki、Iwaya Mai、Sugiura Ayumi、Joshita Satoru、Uehara Takeshi、Umemura Takeji
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1
- DOI
  10.1038/s41598-022-23357-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20884
[Presentation] AIを用いた消化器疾患の診断・治療への応用　NAFLD症例のクラスタリングと肝関連イベントの予測　機械学習を用いた包括的解析2024
- Author(s)
  木村岳史, 若林俊一, 梅村武司
- Organizer
  第110回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-24K11087
[Presentation] B型慢性肝炎における血清トロンボスポンジン2　核酸アナログ製剤治療中の量的変化と肝細胞癌発症リスク2024
- Author(s)
  奥村太規, 木村岳史, 岩垂隆諒, 小林浩幸, 若林俊一, 山下裕騎, 梅村武司
- Organizer
  第60回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-24K11087
[Presentation] C型慢性肝炎における血清トロンボスポンジン2　DAA治療による変化と肝発癌予測2024
- Author(s)
  岩垂隆諒, 木村岳史, 奥村太規, 小林浩幸, 若林俊一, 山下裕騎, 梅村武司
- Organizer
  JDDW2024
- Data Source
  KAKENHI-PROJECT-24K11087
[Presentation] B型慢性肝炎における血清トロンボスポンジン2　核酸アナログ製剤治療中の量的変化と肝細胞癌発症リスク2024
- Author(s)
  奥村太規, 木村岳史, 岩垂隆諒, 小林浩幸, 若林俊一, 山下裕騎, 梅村武司
- Organizer
  第60回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K20884
[Presentation] rognosis of lean and non-lean MASLD in a large-scale Asian population study2024
- Author(s)
  Shun-ichi Wakabayashi, Takefumi Kimura, Nobuharu Tamaki
- Organizer
  AASLD The Liver Meeting 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K11087
[Presentation] 肝硬変:基礎から臨床Cutting edge　トロンボスポンジン2はMASLDにおける肝線維形成の重要な決定因子である2024
- Author(s)
  木村岳史, 田中直樹, 梅村武司
- Organizer
  第60回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K20884
[Presentation] Thrombospondin 2: A Key Player in Fibrogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease Uncovered by Multi-Omics Analysis2024
- Author(s)
  Takefumi Kimura
- Organizer
  AASLD Liver Meeting 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20884
[Presentation] Thrombospondin 2: A Key Player in Fibrogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease Uncovered by Multi-Omics Analysis2024
- Author(s)
  Takefumi Kimura
- Organizer
  AASLD The Liver Meeting 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K11087
[Presentation] NAFLDにおけるトロンボスポンジン2　Bioinformaticsから導かれる肝線維化の新機軸2023
- Author(s)
  木村岳史
- Organizer
  JDDW 2023
- Data Source
  KAKENHI-PROJECT-22K20884
[Presentation] 血清トロンボスポンジン2はC型肝炎の病勢を反映する良いバイオマーカーである2023
- Author(s)
  岩垂隆諒, 木村岳史
- Organizer
  第59回肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K20884
[Presentation] THROMBOSPONDIN 2 LEVELS REFLECT DISEASE ACTIVITY IN HCV-INFECTED PATIENTS2023
- Author(s)
  Takefumi Kimura
- Organizer
  DDW 2023 Chicago
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20884
[Presentation] 肝硬変におけるトロンボスポンジン2の臨床的意義　C型肝炎とNAFLDによる比較検討2023
- Author(s)
  木村岳史
- Organizer
  第59回肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K20884

1. 城下智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kimura Takefumi 木村 岳史

Research Projects

Research Products

Co-Researchers

Examining the Hypothesis: Suppression of THBS2 Gene Alleviates Liver FibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of a Novel Liver Fibrosis Mechanism Mediated by Thrombospondin 2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Thrombospondin 2 as a Predictive Biomarker for <scp>HCC</scp> in?Hepatitis C Patients: A Longitudinal Study Following <scp>DAA</scp> Therapy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum Autotaxin Levels Predict Liver-Related Events in Patients With Primary Biliary Cholangitis: A Long-Term Multicenter Observational Study2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Circulating thrombospondin 2 as a predictor of hepatocellular carcinoma in hepatitis B patients undergoing nucleos(t)ide analog therapy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Thrombospondin 2 is a key determinant of fibrogenesis in non‐alcoholic fatty liver disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Circulating thrombospondin 2 levels reflect fibrosis severity and disease activity in HCV-infected patients2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] AIを用いた消化器疾患の診断・治療への応用 NAFLD症例のクラスタリングと肝関連イベントの予測 機械学習を用いた包括的解析2024

Author(s)

Organizer

Data Source

[Presentation] B型慢性肝炎における血清トロンボスポンジン2 核酸アナログ製剤治療中の量的変化と肝細胞癌発症リスク2024

Author(s)

Organizer

Data Source

[Presentation] C型慢性肝炎における血清トロンボスポンジン2 DAA治療による変化と肝発癌予測2024

Author(s)

Organizer

Data Source

[Presentation] B型慢性肝炎における血清トロンボスポンジン2 核酸アナログ製剤治療中の量的変化と肝細胞癌発症リスク2024

Author(s)

Organizer

Data Source

[Presentation] rognosis of lean and non-lean MASLD in a large-scale Asian population study2024

Author(s)

Organizer

Data Source

[Presentation] 肝硬変:基礎から臨床Cutting edge トロンボスポンジン2はMASLDにおける肝線維形成の重要な決定因子である2024

Author(s)

Organizer

Data Source

[Presentation] Thrombospondin 2: A Key Player in Fibrogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease Uncovered by Multi-Omics Analysis2024

Author(s)

Organizer

Data Source

[Presentation] Thrombospondin 2: A Key Player in Fibrogenesis of Metabolic Dysfunction-Associated Steatotic Liver Disease Uncovered by Multi-Omics Analysis2024

Author(s)

Organizer

Data Source

[Presentation] NAFLDにおけるトロンボスポンジン2 Bioinformaticsから導かれる肝線維化の新機軸2023

Author(s)

Organizer

Data Source

[Presentation] 血清トロンボスポンジン2はC型肝炎の病勢を反映する良いバイオマーカーである2023

Author(s)

Organizer

Kimura Takefumi 木村岳史

[Presentation] AIを用いた消化器疾患の診断・治療への応用　NAFLD症例のクラスタリングと肝関連イベントの予測　機械学習を用いた包括的解析2024

[Presentation] B型慢性肝炎における血清トロンボスポンジン2　核酸アナログ製剤治療中の量的変化と肝細胞癌発症リスク2024

[Presentation] C型慢性肝炎における血清トロンボスポンジン2　DAA治療による変化と肝発癌予測2024

[Presentation] B型慢性肝炎における血清トロンボスポンジン2　核酸アナログ製剤治療中の量的変化と肝細胞癌発症リスク2024

[Presentation] 肝硬変:基礎から臨床Cutting edge　トロンボスポンジン2はMASLDにおける肝線維形成の重要な決定因子である2024

[Presentation] NAFLDにおけるトロンボスポンジン2　Bioinformaticsから導かれる肝線維化の新機軸2023

[Presentation] 肝硬変におけるトロンボスポンジン2の臨床的意義　C型肝炎とNAFLDによる比較検討2023