Hasegawa Hideaki 長谷川英哲

Researcher Number	80935669
Affiliation (Current)	2026: 東京医科大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2024: 東京医科大学, 医学部, 非常勤講師 2022 – 2023: 東京医科大学, 医学部, 兼任助教
Review Section/Research Field	Principal Investigator Basic Section 53050:Dermatology-related
Keywords	Principal Investigator AhR / イミキモド / ASK1 / 乾癬

Mechanism of action of ASK1, a stress-responsive MAP kinase, in a model of imiquimod-induced psoriasis.Principal Investigator
- Principal Investigator
  
  Hasegawa Hideaki
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Tokyo Medical University

All 2025 2024 2023 2022

All Journal Article Presentation

[Journal Article] Wound Healing Enhancement and Physical Characterization of Bioadhesive Poly(Acrylic Acid)/Polyvinylpyrrolidone Complex Gels.2025
- Author(s)
  Oouchi A, Ito T, Katahira Y, Hasegawa H, Nakamura K, Mizoguchi I, Yoshimoto T, Koyama Y.
- Journal Title
  
  Gels
  
  Volume: 11(4) Issue: 4 Pages: 300-300
- DOI
  10.3390/gels11040300
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K12772, KAKENHI-PROJECT-22K15696, KAKENHI-PROJECT-22K16291, KAKENHI-PROJECT-24K15306
[Journal Article] Protective effect of conditioned medium of immortalized human stem cells from exfoliated deciduous teeth against hair graying caused by X-ray irradiation via its antioxidative activity.2025
- Author(s)
  Katahira Y, Horio E, Yamaguchi N, Sonoda J, Yamagishi M, Miyakawa S, Murakami F, Hasegawa H, Mizoguchi I, Yoshimoto T.
- Journal Title
  
  Antioxidants (Basel)
  
  Volume: 14(1) Issue: 1 Pages: 109-109
- DOI
  10.3390/antiox14010109
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07504, KAKENHI-PROJECT-22K08722, KAKENHI-PROJECT-23K09087, KAKENHI-PROJECT-22K15696, KAKENHI-PROJECT-22K16291, KAKENHI-PROJECT-24K12100, KAKENHI-PROJECT-24K12566, KAKENHI-PROJECT-24K15306
[Journal Article] Topical application of Cha-Koji, green tea leaves fermented with Aspergillus Luchuensis var Kawachii Kitahara, promotes acute cutaneous wound healing in mice2024
- Author(s)
  Katahira Y, Sonoda J, Yamagishi M, Horio E, Yamaguchi N, Hasegawa H, Mizoguchi I,Yoshimoto T
- Journal Title
  
  Sci. Pharm.
  
  Volume: 92(3) Issue: 3 Pages: 44-44
- DOI
  10.3390/scipharm92030044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15696, KAKENHI-PROJECT-22K16291, KAKENHI-PROJECT-24K15306
[Journal Article] Immortalization of mesenchymal stem cells for application in regenerative medicine and their potential risks of tumorigenesis.2024
- Author(s)
  Yamaguchi N, Horio E, Sonoda J, Yamagishi M, Miyakawa S, Murakami F, Hasegawa H, Katahira Y, Mizoguchi I, Fujii Y, Chikazu D, Yoshimoto T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 25(24) Issue: 24 Pages: 13562-13562
- DOI
  10.3390/ijms252413562
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07504, KAKENHI-PROJECT-22K08722, KAKENHI-PROJECT-23K09087, KAKENHI-PROJECT-22K15696, KAKENHI-PROJECT-22K16291, KAKENHI-PROJECT-24K12100, KAKENHI-PROJECT-24K12566, KAKENHI-PROJECT-24K15306
[Journal Article] A Promising Needle-Free Pyro-Drive Jet Injector for Augmentation of Immunity by Intradermal Injection as a Physical Adjuvant2023
- Author(s)
  Jukito Sonoda,Izuru Mizoguchi,Shinya Inoue,Aruma Watanabe,Ami Sekine,Miu Yamagishi,Satomi Miyakawa,Natsuki Yamaguchi,Eri Horio,Yasuhiro Katahira,Hideaki Hasegawa,Takashi Hasegawa,Kunihiko Yamashita and Takayuki Yoshimoto
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 24 Issue: 10 Pages: 9094-9094
- DOI
  10.3390/ijms24109094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15696, KAKENHI-PROJECT-22K16291, KAKENHI-PROJECT-22K07504, KAKENHI-PROJECT-22K12772, KAKENHI-PROJECT-23K09087, KAKENHI-PROJECT-21K12256, KAKENHI-PROJECT-22K08018
[Journal Article] Chemical- and Drug-Induced Allergic, Inflammatory, and Autoimmune Diseases via Haptenation.2023
- Author(s)
  Sakamoto E, Katahira Y, Watanabe A, Furusaka Y, Sekine A, Yamagishi M, Sonoda J, Miyakawa S, Inoue S, Hasegawa H, Yo K, Yamaji F, Toyoda T, Mizoguchi I, Yoshimoto T.
- Journal Title
  
  Biology (Basel)
  
  Volume: 12(1) Issue: 1 Pages: 123-123
- DOI
  10.3390/biology12010123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K12256, KAKENHI-PROJECT-22K07504, KAKENHI-PROJECT-22K08018, KAKENHI-PROJECT-22K15696, KAKENHI-PROJECT-22K16291, KAKENHI-PROJECT-23K09087
[Journal Article] Potent antitumor effects of the conditioned medium of bone marrow-derived mesenchymal stem cells via IGFBP-4.2023
- Author(s)
  Furusaka Y, Inoue S, Mizoguchi I, Hasegawa H, Katahira Y, Watanabe A, Sakamoto E, Sekine A, Miyakawa S, Umezu T, Owaki T, Yoneto T, Yoshimoto T.
- Journal Title
  
  Cancer Sci.
  
  Volume: in press Issue: 6 Pages: 2499-2514
- DOI
  10.1111/cas.15789
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07504, KAKENHI-PROJECT-22K08018, KAKENHI-PROJECT-22K15696, KAKENHI-PROJECT-22K16291, KAKENHI-PROJECT-22K08722, KAKENHI-PROJECT-22K12772, KAKENHI-PROJECT-23K09087, KAKENHI-PROJECT-21K07133, KAKENHI-PROJECT-21K09779, KAKENHI-PROJECT-21K12256
[Journal Article] Protective effects of conditioned media of immortalized stem cells from human exfoliated deciduous teeth on pressure ulcer formation.2023
- Author(s)
  Katahira Y, Murakami M, Inoue S, Miyakawa S, Sakamoto E, Furusaka Y, Watanabe A, Sekine A, Kuroda M, Hasegawa H, Mizoguchi I, Yoshimoto T.
- Journal Title
  
  Front Immunol.
  
  Volume: 13 Pages: 1010700-1010700
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16291
[Journal Article] Induction of potent antitumor immunity by intradermal <scp>DNA</scp> injection using a novel needle‐free pyro‐drive jet injector2022
- Author(s)
  Inoue Shinya、Mizoguchi Izuru、Sonoda Jukito、Sakamoto Eri、Katahira Yasuhiro、Hasegawa Hideaki、Watanabe Aruma、Furusaka Yuma、Xu Mingli、Yoneto Toshihiko、Sakaguchi Naoki、Terai Kazuhiro、Yamashita Kunihiko、Yoshimoto Takayuki
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 1 Pages: 34-47
- DOI
  10.1111/cas.15542
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11227, KAKENHI-PROJECT-22K16291, KAKENHI-PROJECT-22K07504, KAKENHI-PROJECT-22K12772, KAKENHI-PROJECT-23K09087, KAKENHI-PROJECT-21K12256
[Journal Article] A novel coculture system for assessing respiratory sensitizing potential by IL-4 in T cells.2022
- Author(s)
  Izuru Mizoguchi, Yasuhiro Katahira, Shinya Inoue, Eri Sakamoto, Aruma Watanabe, Yuma Furusaka, Atsushi Irie, Satoru Senju, Yasuharu Nishimura, Shusaku Mizukami, Kenji Hirayama, Sou Nakamura, Koji Eto, Hideaki Hasegawa, Takayuki Yoshimoto
- Journal Title
  
  ALTEX
  
  Volume: - Pages: 204-216
- DOI
  10.14573/altex.2111181
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08008, KAKENHI-PROJECT-21K11227, KAKENHI-PROJECT-21K12256, KAKENHI-PROJECT-22K16291, KAKENHI-PROJECT-22K08722, KAKENHI-PROJECT-21K07917
[Journal Article] Upregulation of CD86 and IL-12 by rhododendrol in THP-1 cells cocultured with melanocytes through ROS and ATP2022
- Author(s)
  Katahira Yasuhiro、Sakamoto Eri、Watanabe Aruma、Furusaka Yuma、Inoue Shinya、Hasegawa Hideaki、Mizoguchi Izuru、Yo Kazuyuki、Yamaji Fumiya、Toyoda Akemi、Yoshimoto Takayuki
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 108 Issue: 3 Pages: 167-177
- DOI
  10.1016/j.jdermsci.2022.12.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11227, KAKENHI-PROJECT-22K15696, KAKENHI-PROJECT-22K16291
[Presentation] Therapeutic effects of a novel human placental extract against chemotherapy-induced peripheral neuropathy.2024
- Author(s)
  Yoshimoto T, Horio E, Yamaguchi N, Hasegawa H, Katahira Y, Yamagishi M, Sonoda J, Miyakawa S, Yoneto T, Xu M, Ikeda S, Amamizu H, Matsumoto H, Mizoguchi I.
- Organizer
  Cytokines 2024 and KAI2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16291
[Presentation] Protective effect of conditioned medium of immortalized human exfoliated deciduous teeth against peripheral nerve injury in a sciatic nerve crush mouse model.2024
- Author(s)
  Yamaguchi N, Hasegawa H, Watanabe A, Horio E, Yamagishi M, Sonoda J, Miyakawa S, Inoue S, Murakami F, Anamizu H, Yoneto T, Xu M, Katahira Y, Mizoguchi I, Yoshimoto T.
- Organizer
  The 1st Annual Meeting of the Japanese Cytokine Society
- Data Source
  KAKENHI-PROJECT-22K16291
[Presentation] Induction of potent antitumor immunity by intradermal injection of protein using a needle-free pyro-drive jet injection.2024
- Author(s)
  Mizoguchi I, Sonoda J, Yamaguchi N, Horio E, Miyakawa S, Xu M, Yoneto Y, Katahira Y, Hasegawa H, Hasegawa K, Yamashita K, Yoshimoto　T.
- Organizer
  第53回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K16291
[Presentation] Topical application of Cha-koji, the green tea leaves fermented with Aspergillus lunchuensis ver kawachii kitahara, on the skin promotes acute cutaneous wound healing in mice.2024
- Author(s)
  Katahira Y, Watanabe A, Miyakawa S, Hasegawa H, Mizoguchi I, Yoshimoto T.
- Organizer
  第52回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K16291
[Presentation] Inhibition of melanogenesis by conditioned medium of an immortalized stem cell line from human exfoliated deciduous teeth through possibly Wnt5a-mediated suppression of Wnt signaling.2024
- Author(s)
  Sekine A, Katahira Y, Watanabe A, Miyakawa S, Hasegawa H, Mizoguchi I, Yoshimoto T.
- Organizer
  第52回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K16291
[Presentation] イミキモド誘導性乾癬モデルにおけるストレス応答性MAPキナーゼASK1の役割とその作用機序2023
- Author(s)
  長谷川英哲、渡邉有麻、溝口　出、片平泰弘、関根碧水、山岸美宇、園田寿希心、宮川聡美、前田龍郎、原田和俊、大久保ゆかり、善本隆之
- Organizer
  第38回日本乾癬学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-22K16291
[Presentation] 呼吸器と皮膚感作性物質の識別を可能にするTh2細胞株を応用した改良版2ステップDC/T共培養系の開発2023
- Author(s)
  溝口出、片平泰弘、長谷川英哲、渡邉有麻、関根碧水、園田寿樹心、山岸美宇、善本隆之
- Organizer
  第36回日本動物実験代替法学会
- Data Source
  KAKENHI-PROJECT-22K16291
[Presentation] Topical application of Cha-koji, the green tea leaves fermented with Aspergillus lunchuensis ver kawachii kitahara, on the skin promotes acute cutaneous wound healing in mice.2023
- Author(s)
  Katahira Y, Watanabe A, Miyakawa S, Hasegawa H, Mizoguchi I, Yoshimoto T.
- Organizer
  第52回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K16291
[Presentation] Induction of CD8+ T cell-mediated antitumor immunity by intradermal protein injection with a new pyro-derive jet injector.2023
- Author(s)
  Sonoda J, Mizoguchi I, Katahira Y, Hasegawa H, Yamashita K, Yoshimoto T.
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K16291
[Presentation] Conditioned medium of immortalized stem cells from human exfoliated deciduous teeth inhibit melanogenesis by suppressing Wnt signaling via Wnt5a.2023
- Author(s)
  Inoue S, Sekine A, Katahira Y, Yamagishi M, Sonoda J, Watanabe A, Miyakawa S, Hasegawa H, Mizoguchi I, Yoshimoto T.
- Organizer
  JSICR/MMCB 2023 Joint Symposium
- Data Source
  KAKENHI-PROJECT-22K16291
[Presentation] Protective effect of conditioned medium of immortalized stem cells from human exfoliated deciduous tooth on the peripheral neuropathy of experimental autoimmune neuritis.JSICR/MMCB 2022 Joint Symposium2022
- Author(s)
  Hasegawa H, Sakamoto E, Katahira Y, Miyakawa S, Murakami F, Inoue S, Watanabe A, Furusaka Y, SekineA, Owaki T, Mizoguchi I, Yoshimoto T.
- Organizer
  JSICR/MMCB 2022 Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16291
[Presentation] Conditioned medium of immortalized stem cells from human exfoliated deciduous tooth exhibit protective effect on the peripheral neuropathy of experimental autoimmune neuritis.2022
- Author(s)
  Sakamoto E, Hasegawa H, Katahira Y, Miyakawa S, Watanabe A, Mizoguchi I, Yoshimoto T.
- Organizer
  第51回日本免疫学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-22K16291
[Presentation] 化粧品美白成分ロドデノールはメラノサイトでの活性酸素と細胞外ATPの産生を介し樹状細胞での共刺激分子CD86発現を増2022
- Author(s)
  片平泰弘、坂本恵梨、古阪悠馬、渡邉有麻、関根碧水、山岸美宇、園田寿希心、長谷川英哲、溝口出、善本隆之
- Organizer
  第35回日本動物実験代替法学会
- Data Source
  KAKENHI-PROJECT-22K16291
[Presentation] 骨髄由来間葉系幹細胞の腫瘍増殖の抑制効果とその作用機序2022
- Author(s)
  米戸敏彦、古阪悠馬、片平泰弘、宮川聡美、長谷川英哲、溝口出、善本隆之
- Organizer
  第30回乳癌基礎研究会
- Data Source
  KAKENHI-PROJECT-22K16291
[Presentation] Inhibitory effects of bone marrow-derived mesenchymal stem cells on tumor growth and its possible molecular mechanism.2022
- Author(s)
  Furusaka Y, Katahira Y, Hasegawa H, Umezu T, Mizoguchi I, Yoneto T, Yoshimoto T.
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K16291

1. 片平泰弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 徐明利

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 善本隆之

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
4. 溝口出

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 宮川聡美

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 入江厚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hasegawa Hideaki 長谷川 英哲

Research Projects

Research Products

Co-Researchers

Mechanism of action of ASK1, a stress-responsive MAP kinase, in a model of imiquimod-induced psoriasis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Wound Healing Enhancement and Physical Characterization of Bioadhesive Poly(Acrylic Acid)/Polyvinylpyrrolidone Complex Gels.2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protective effect of conditioned medium of immortalized human stem cells from exfoliated deciduous teeth against hair graying caused by X-ray irradiation via its antioxidative activity.2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Topical application of Cha-Koji, green tea leaves fermented with Aspergillus Luchuensis var Kawachii Kitahara, promotes acute cutaneous wound healing in mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immortalization of mesenchymal stem cells for application in regenerative medicine and their potential risks of tumorigenesis.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Promising Needle-Free Pyro-Drive Jet Injector for Augmentation of Immunity by Intradermal Injection as a Physical Adjuvant2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemical- and Drug-Induced Allergic, Inflammatory, and Autoimmune Diseases via Haptenation.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Potent antitumor effects of the conditioned medium of bone marrow-derived mesenchymal stem cells via IGFBP-4.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protective effects of conditioned media of immortalized stem cells from human exfoliated deciduous teeth on pressure ulcer formation.2023

Author(s)

Journal Title

Data Source

[Journal Article] Induction of potent antitumor immunity by intradermal <scp>DNA</scp> injection using a novel needle‐free pyro‐drive jet injector2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel coculture system for assessing respiratory sensitizing potential by IL-4 in T cells.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Upregulation of CD86 and IL-12 by rhododendrol in THP-1 cells cocultured with melanocytes through ROS and ATP2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Therapeutic effects of a novel human placental extract against chemotherapy-induced peripheral neuropathy.2024

Author(s)

Organizer

Data Source

[Presentation] Protective effect of conditioned medium of immortalized human exfoliated deciduous teeth against peripheral nerve injury in a sciatic nerve crush mouse model.2024

Author(s)

Organizer

Data Source

[Presentation] Induction of potent antitumor immunity by intradermal injection of protein using a needle-free pyro-drive jet injection.2024

Author(s)

Organizer

Data Source

[Presentation] Topical application of Cha-koji, the green tea leaves fermented with Aspergillus lunchuensis ver kawachii kitahara, on the skin promotes acute cutaneous wound healing in mice.2024

Author(s)

Organizer

Data Source

Hasegawa Hideaki 長谷川英哲