Enzan Nobuyuki 円山信之

… Alternative Names

円山信之エンザンノブユキ

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Researcher Number	80962919
Other IDs
Affiliation (Current)	2026: 国際医療福祉大学, 福岡保健医療学部, 研究員 2026: 国際医療福祉大学, 医学部, 研究員 2026: 国際医療福祉大学, その他部局等, 研究員
Affiliation (based on the past Project Information) *help	2023: 国立研究開発法人理化学研究所, 生命医科学研究センター, リサーチアソシエイト
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator リスクスコア / 遺伝学 / オミクス / 心不全 / ゲノムワイド関連解析

オミクス解析を用いた心不全の遺伝的基盤・新規バイオマーカー・創薬ターゲットの解明Principal Investigator
- Principal Investigator
  
  円山信之
- Project Period (FY)
  2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Institute of Physical and Chemical Research

All 2024 2023

All Journal Article Presentation Patent

[Journal Article] Atrial fibrillation type and long-term clinical outcomes in hospitalized patients with heart failure: insight from JROADHF2024
- Author(s)
  Hamatani Yasuhiro、Enzan Nobuyuki、Iguchi Moritake、Yoshizawa Takashi、Kawaji Tetsuma、Ide Tomomi、Tohyama Takeshi、Matsushima Shouji、Abe Mitsuru、Tsutsui Hiroyuki、Akao Masaharu
- Journal Title
  
  European Heart Journal - Quality of Care and Clinical Outcomes
  
  Volume: - Issue: 3 Pages: 193-202
- DOI
  10.1093/ehjqcco/qcae005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15144
[Journal Article] Evaluation of the A2B Score for Prediction of Survival in Patients With Heart Failure in a Nationwide Cohort in Japan2024
- Author(s)
  Kyodo Atsushi、Nakada Yasuki、Nogi Maki、Nogi Kazutaka、Ishihara Satomi、Ueda Tomoya、Tohyama Takeshi、Enzan Nobuyuki、Ide Tomomi、Matsushima Shouji、Tsutsui Hiroyuki、Saito Yoshihiko
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 13 Issue: 4
- DOI
  10.1161/jaha.123.031104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15144
[Journal Article] IFN-γ-STAT1-ERK Pathway Mediates?Protective Effects of Invariant?Natural Killer T Cells Against?Doxorubicin-Induced Cardiomyocyte Death2023
- Author(s)
  Sada Masashi、Matsushima Shouji、Ikeda Masataka、Ikeda Soichiro、Okabe Kosuke、Ishikita Akihito、Tadokoro Tomonori、Enzan Nobuyuki、Yamamoto Taishi、Miyamoto Hiroko Deguchi、Tsutsui Yoshitomo、Miyake Ryo、Setoyama Daiki、Kang Dongchon、Ide Tomomi、Tsutsui Hiroyuki
- Journal Title
  
  JACC: Basic to Translational Science
  
  Volume: 8 Issue: 8 Pages: 992-1007
- DOI
  10.1016/j.jacbts.2023.02.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08082, KAKENHI-PROJECT-21K16090, KAKENHI-PROJECT-23K15144
[Journal Article] A higher resting heart rate is associated with cardiovascular event risk in patients with type 2 diabetes mellitus without known cardiovascular disease2023
- Author(s)
  Ikeda Shota、Shinohara Keisuke、Enzan Nobuyuki、Matsushima Shouji、Tohyama Takeshi、Funakoshi Kouta、Kishimoto Junji、Itoh Hiroshi、Komuro Issei、Tsutsui Hiroyuki
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 5 Pages: 1090-1099
- DOI
  10.1038/s41440-023-01178-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15144
[Journal Article] ZBP1 Protects Against mtDNA-Induced Myocardial Inflammation in Failing Hearts2023
- Author(s)
  Enzan Nobuyuki、Matsushima Shouji、Ikeda Soichiro、Okabe Kosuke、Ishikita Akihito、Yamamoto Taishi、Sada Masashi、...Tsutsui Hiroyuki
- Journal Title
  
  Circulation Research
  
  Volume: - Issue: 9 Pages: 1110-1126
- DOI
  10.1161/circresaha.122.322227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16026, KAKENHI-PROJECT-21K08082, KAKENHI-PROJECT-21H03360, KAKENHI-PROJECT-22K19754, KAKENHI-PROJECT-23K15144
[Journal Article] Long-Term Outcomes of Heart?Failure Patients With Preserved, Mildly Reduced, and Reduced Ejection Fraction2023
- Author(s)
  Nagata Takuya、Ide Tomomi、Tohyama Takeshi、Kaku Hidetaka、Enzan Nobuyuki、Matsushima Shouji、Ikeda Masataka、Todaka Koji、Tsutsui Hiroyuki
- Journal Title
  
  JACC: Asia
  
  Volume: - Issue: 2 Pages: 315-316
- DOI
  10.1016/j.jacasi.2022.11.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16141, KAKENHI-PROJECT-23K15144
[Journal Article] Propensity-Matched Study of Early Cardiac Rehabilitation in Patients With Acute Decompensated Heart Failure2023
- Author(s)
  Enzan Nobuyuki、Matsushima Shouji、Kaku Hidetaka、Tohyama Takeshi、Nezu Tomoyuki、Higuchi Tae、Nagatomi Yuta、Fujino Takeo、Hashimoto Toru、Ide Tomomi、Tsutsui Hiroyuki
- Journal Title
  
  Circulation: Heart Failure
  
  Volume: - Issue: 4
- DOI
  10.1161/circheartfailure.122.010320
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08126, KAKENHI-PROJECT-19K17567, KAKENHI-PROJECT-23K15144
[Journal Article] Nationwide Temporal Trends in Clinical Characteristics and Treatment of Dilated Cardiomyopathy From 2003 to 2013 in Japan　― A Report From Clinical Personal Records ―2023
- Author(s)
  Tsutsui Yoshitomo、Matsushima Shouji、Enzan Nobuyuki、Noda Eri、Shinohara Keisuke、Hashimoto Toru、Ide Tomomi、Kinugawa Shintaro、Tsutsui Hiroyuki
- Journal Title
  
  Circ J
  
  Volume: 87 Issue: 4 Pages: 500-507
- DOI
  10.1253/circj.CJ-22-0554
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2023-03-24
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08126, KAKENHI-PROJECT-19K17567, KAKENHI-PROJECT-23K15144
[Journal Article] Efficacy of Early Catheter Ablation for Atrial Fibrillation After Admission for Heart Failure2023
- Author(s)
  Kazuo Sakamoto, Takeshi Tohyama, Tomomi Ide, Yasushi Mukai, Nobuyuki Enzan, Takuya Nagata, Masataka Ikeda, Susumu Takase, Tomomi Nagayama, Takeo Fujino, Shouji Matsushima, Hiroyuki Tsutsui
- Journal Title
  
  JACC Clin Electrophysiol
  
  Volume: 9 Issue: 9 Pages: 1948-1959
- DOI
  10.1016/j.jacep.2023.05.038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16141, KAKENHI-PROJECT-23K15144
[Journal Article] Regional Variation in the Clinical Practice and Prognosis in Patients With Heart Failure With Reduced Ejection Fraction in Japan　― A Report From the Japanese Registry of Acute Decompensated Heart Failure (JROADHF) ―2023
- Author(s)
  Sato Yu、Yoshihisa Akiomi、Ide Tomomi、Tohyama Takeshi、Enzan Nobuyuki、Matsushima Shouji、Tsutsui Hiroyuki、Takeishi Yasuchika
- Journal Title
  
  Circ J
  
  Volume: 87 Issue: 10 Pages: 1380-1391
- DOI
  10.1253/circj.CJ-22-0774
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2023-09-25
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06870, KAKENHI-PROJECT-23K15144
[Journal Article] Beneficial Effects of Dipeptidyl Peptidase-4 Inhibitors on Heart?Failure?With Preserved Ejection?Fraction and Diabetes2023
- Author(s)
  Enzan Nobuyuki、Matsushima Shouji、Kaku Hidetaka、Tohyama Takeshi、Nagata Takuya、Ide Tomomi、Tsutsui Hiroyuki
- Journal Title
  
  JACC: Asia
  
  Volume: 3 Issue: 1 Pages: 93-104
- DOI
  10.1016/j.jacasi.2022.09.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16141, KAKENHI-PROJECT-23K15144
[Journal Article] Prevalence, characteristics and cardiovascular and non‐cardiovascular outcomes in patients with heart failure with supra‐normal ejection fraction: Insight from the JROADHF study2023
- Author(s)
  Horiuchi Yu、Asami Masahiko、Ide Tomomi、Yahagi Kazuyuki、Komiyama Kota、Yuzawa Hitomi、Tanaka Jun、Aoki Jiro、Matsushima Shouji、Tohyama Takeshi、Enzan Nobuyuki、Tsutsui Hiroyuki、Tanabe Kengo
- Journal Title
  
  European Journal of Heart Failure
  
  Volume: 25 Issue: 7 Pages: 989-998
- DOI
  10.1002/ejhf.2895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15144
[Patent] 心不全のリスク判定方法及びリスク判定システム2024
- Inventor(s)
  円山信之/伊藤薫
- Industrial Property Rights Holder
  円山信之/伊藤薫
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-051916
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-23K15144
[Presentation] ZBP1 protects against mitochondrial DNA-induced myocardial inflammation in failing hearts by suppressing RIPK3-NF-κB pathway2023
- Author(s)
  Nobuyuki Enzan
- Organizer
  第87回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15144
[Presentation] The use of mineralocorticoid receptor antagonists but not renin-angiotensin system inhibitors is associated with better outcomes in patients with heart failure and advanced chronic kidney disease2023
- Author(s)
  Nobuyuki Enzan
- Organizer
  American Heart Association Scientific Sessions 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15144
[Presentation] In-hospital cardiac rehabilitation is associated with better long-term outcomes in patients with acute decompensated heart failure2023
- Author(s)
  Nobuyuki Enzan
- Organizer
  第27回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15144

1. 松島将士

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 筒井裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 池田宗一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 永田拓也

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
5. 橋本亨

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Enzan Nobuyuki 円山 信之

円山 信之 エンザン ノブユキ

Research Projects

Research Products

Co-Researchers

オミクス解析を用いた心不全の遺伝的基盤・新規バイオマーカー・創薬ターゲットの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Atrial fibrillation type and long-term clinical outcomes in hospitalized patients with heart failure: insight from JROADHF2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of the A2B Score for Prediction of Survival in Patients With Heart Failure in a Nationwide Cohort in Japan2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IFN-γ-STAT1-ERK Pathway Mediates?Protective Effects of Invariant?Natural Killer T Cells Against?Doxorubicin-Induced Cardiomyocyte Death2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A higher resting heart rate is associated with cardiovascular event risk in patients with type 2 diabetes mellitus without known cardiovascular disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ZBP1 Protects Against mtDNA-Induced Myocardial Inflammation in Failing Hearts2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-Term Outcomes of Heart?Failure Patients With Preserved, Mildly Reduced, and Reduced Ejection Fraction2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Propensity-Matched Study of Early Cardiac Rehabilitation in Patients With Acute Decompensated Heart Failure2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nationwide Temporal Trends in Clinical Characteristics and Treatment of Dilated Cardiomyopathy From 2003 to 2013 in Japan ― A Report From Clinical Personal Records ―2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Efficacy of Early Catheter Ablation for Atrial Fibrillation After Admission for Heart Failure2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regional Variation in the Clinical Practice and Prognosis in Patients With Heart Failure With Reduced Ejection Fraction in Japan ― A Report From the Japanese Registry of Acute Decompensated Heart Failure (JROADHF) ―2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Beneficial Effects of Dipeptidyl Peptidase-4 Inhibitors on Heart?Failure?With Preserved Ejection?Fraction and Diabetes2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prevalence, characteristics and cardiovascular and non‐cardiovascular outcomes in patients with heart failure with supra‐normal ejection fraction: Insight from the JROADHF study2023

Author(s)

Journal Title

DOI

Data Source

[Patent] 心不全のリスク判定方法及びリスク判定システム2024

Inventor(s)

Industrial Property Rights Holder

Enzan Nobuyuki 円山信之

円山信之エンザンノブユキ

[Journal Article] Nationwide Temporal Trends in Clinical Characteristics and Treatment of Dilated Cardiomyopathy From 2003 to 2013 in Japan　― A Report From Clinical Personal Records ―2023

[Journal Article] Regional Variation in the Clinical Practice and Prognosis in Patients With Heart Failure With Reduced Ejection Fraction in Japan　― A Report From the Japanese Registry of Acute Decompensated Heart Failure (JROADHF) ―2023