SHICHIJO TAKAFUMI 七條敬文

Researcher Number	80973891
Other IDs
Affiliation (Current)	2026: 熊本大学, 大学院生命科学研究部(医), 助教
Affiliation (based on the past Project Information) *help	2023 – 2025: 熊本大学, 大学院生命科学研究部(医), 助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator HBZ / ATL / HTLV-1 / シグナルカスケード / TGF-β / TGF-β/Smad経路 / APOBEC3G / HTLV-1 bZIP factor / ヒトT細胞白血病ウイルス1型 / 成人T細胞白血病 / TGF-beta … More Except Principal Investigator … More 樹状細胞 / ウイルス発がん / HBZ / ATL / HTLV-1 Less

成人T細胞白血病の自然寛解のメカニズム解明と免疫療法への展開
- Principal Investigator
  
  松岡雅雄
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kumamoto University
TGF-β誘導性ATL特異的シグナルカスケードによる発がん機構解明と治療標的探索Principal Investigator
- Principal Investigator
  
  七條敬文
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kumamoto University
HTLV-1の適応進化不全によるATL発がん機構の解明と新規治療薬の探索Principal Investigator
- Principal Investigator
  
  七條敬文
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kumamoto University

All 2025 2024 2023

All Journal Article Presentation

[Journal Article] Stratagems of HTLV-1 for persistent infection and the resultant oncogenesis: Immune evasion and clonal expansion2025
- Author(s)
  Shichijo Takafumi、Yasunaga Jun-ichirou
- Journal Title
  
  Leukemia Research
  
  Volume: 152 Pages: 107680-107680
- DOI
  10.1016/j.leukres.2025.107680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K22136, KAKENHI-PROJECT-23K15303
[Journal Article] Validity of the criteria for clinical transformation of follicular lymphoma: analysis of a mostly biopsied cohort2025
- Author(s)
  Tatetsu Hiro、Shichijo Takafumi、Nosaka Kisato、Higuchi Yusuke、Maruyama Dai、Matsuoka Masao、Yasunaga Jun-ichirou
- Journal Title
  
  Annals of Hematology
  
  Volume: - Issue: 4 Pages: 2575-2578
- DOI
  10.1007/s00277-025-06357-3
- Data Source
  KAKENHI-PROJECT-23K15303
[Journal Article] A dendritic cell-like transition of T cells is associated with spontaneous remission of adult T-cell leukemia-lymphoma2025
- Author(s)
  Watanabe Miho、Yasunaga Jun-ichirou、Hussein Osama、Tanaka Azusa、Shichijo Takafumi、Izaki Mikiko、Okamoto Yuki、Komohara Yoshihiro、Matsuoka Masao
- Journal Title
  
  Cancer Immunology Research
  
  Volume: xx Issue: 7 Pages: 1098-1110
- DOI
  10.1158/2326-6066.cir-24-0306
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24365, KAKENHI-PROJECT-24K22136, KAKENHI-PROJECT-23K15303
[Journal Article] Decreased PU.1 expression in mature B cells induces lymphomagenesis2024
- Author(s)
  Endo Shinya、Nishimura Nao,、Okuno Yutaka、Tatetsu Hiro et al.
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 12 Pages: 3890-3901
- DOI
  10.1111/cas.16344
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08420, KAKENHI-PROJECT-22K08546, KAKENHI-PROJECT-23K06454, KAKENHI-PROJECT-24K11563, KAKENHI-PROJECT-24K22136, KAKENHI-PROJECT-23K15303
[Journal Article] Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses.2024
- Author(s)
  Shichijo T, Yasunaga JI, Sato K, Nosaka K, Toyoda K, Watanabe M, Zhang W, Koyanagi Y, Murphy EL, Bruhn RL, Koh K, Akari H, Ikeda T, Harris RS, Green PL, Matsuoka M.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 121 Issue: 13 Pages: 00-00
- DOI
  10.1073/pnas.2309925121
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15303, KAKENHI-PROJECT-23K20041, KAKENHI-PROJECT-20H03514, KAKENHI-PROJECT-23K24365
[Journal Article] Extranodal NK/T-cell lymphoma with localized relapse in bone marrow of lower leg detected using PET-CT2024
- Author(s)
  Nakamura Takahisa、Tatetsu Hiro、Higuchi Yusuke、Endo Shinya、Shiraishi Shinya、Kawanaka Koichi、Imakane Daisuke、Sonoda Miyu、Furuta Rie、Shichijo Takafumi、Honda Yumi、Karube Kennosuke、Mikami Yoshiki、Nosaka Kisato、Matsuoka Masao、Yasunaga Jun-ichirou
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 64 Issue: 1 Pages: 45-51
- DOI
  10.3960/jslrt.23046
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08420, KAKENHI-PROJECT-24K22136, KAKENHI-PROJECT-23K15303, KAKENHI-PROJECT-23K15328
[Journal Article] HTLV-1 bZIP factor-induced reprogramming of lactate metabolism and epigenetic status promote leukemic cell expansion.2023
- Author(s)
  Toyoda K, Yasunaga JI, Shichijo T, Arima Y, Tsujita K, Tanaka A, Salah T, Zhang W, Hussein O, Sonoda M, Watanabe M, Kurita D, Nakashima K, Yamada K, Miyoshi H, Ohshima K and Matsuoka M
- Journal Title
  
  Blood Cancer Discovery
  
  Volume: in press Issue: 5 Pages: 374-393
- DOI
  10.1158/2643-3230.bcd-22-0139
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03689, KAKENHI-PROJECT-21K16270, KAKENHI-PROJECT-23K15303, KAKENHI-PROJECT-20H03514, KAKENHI-PROJECT-23K24365
[Journal Article] Prophylactic effect of tixagevimab-cilgavimab on COVID-19 infection and death in Japanese patients with B cell lymphoma2023
- Author(s)
  Tatetsu Hiro、Higuchi Yusuke、Shichijo Takafumi、Oda Kazutaka、Nakata Hirotomo、Yasunaga Jun-ichirou、Nosaka Kisato、Matsuoka Masao
- Journal Title
  
  International Journal of Hematology
  
  Volume: 118 Issue: 2 Pages: 303-305
- DOI
  10.1007/s12185-023-03629-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16325, KAKENHI-PROJECT-23K15303, KAKENHI-PROJECT-21K08420, KAKENHI-PROJECT-20H03514
[Journal Article] Robust prognostic value of histologic transformation in patients with early progression of follicular lymphoma2023
- Author(s)
  Shichijo Takafumi、Tatetsu Hiro、Nosaka Kisato、Higuchi Yusuke、Kikukawa Yoshitaka、Toyoda Kosuke、Shiraishi Shinya、Yasunaga Jun-ichirou、Matsuoka Masao
- Journal Title
  
  Leukemia & Lymphoma
  
  Volume: 64 Issue: 10 Pages: 1706-1710
- DOI
  10.1080/10428194.2023.2226429
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16325, KAKENHI-PROJECT-23K15303, KAKENHI-PROJECT-21K08420, KAKENHI-PROJECT-20H03514
[Journal Article] Significant response of patients with transformed follicular lymphoma with rapid disease progression to CAR-T therapy2023
- Author(s)
  Hirano Taichi、Tatetsu Hiro、Ueno Shikiko、Shichijo Takafumi、Furukawa Shota、Tsujihashi Mizuho、Miyakawa Toshikazu、Shiraishi Shinya、Higuchi Yusuke、Uchiba Mitsuhiro、Yasunaga Jun-ichirou、Nosaka Kisato、Matsuoka Masao
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 63 Issue: 4 Pages: 266-269
- DOI
  10.3960/jslrt.23033
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16325, KAKENHI-PROJECT-23K15303, KAKENHI-PROJECT-21K08420, KAKENHI-PROJECT-20H03514
[Presentation] CAR-T治療後に発症した末梢性T細胞リンパ腫2024
- Author(s)
  平野太一, 立津央, 加藤光次, 和田敦司, 上野志貴子, 宮里祐子, 樋口悠介, 七條敬文, 野坂生郷, 三上芳樹, 加留部謙之輔, 赤司浩一, 松岡雅雄, 安永純一朗
- Organizer
  第86回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] 成人T細胞白血病細胞におけるJun dimerization protein 2の意義(Significance of Jun dimerization protein 2 in adult T-cell leukemia cells)2024
- Author(s)
  坂田亮, 豊田康祐, 七條敬文, 張文怡, 松岡雅雄, 安永純一朗
- Organizer
  第83回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] CAR-T療法を目指した再発・難治性濾胞性リンパ腫4例の経験2024
- Author(s)
  渡辺美穂, 立津央, 平野太一, 上野志貴子, 七條敬文, 樋口悠介, 坂井亜夕子, 和田敦司, 山田麻美, 山村綾子, 岩永幸太, 古賀健一, 野坂生郷, 松岡雅雄, 安永純一朗
- Organizer
  第86回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] Spatio-temporal variation of HTLV-1 bZIP factor protein is associated with leukemogenesis of HTLV-12024
- Author(s)
  Wenyi Zhang, Takafumi Shichijo, Masao Matsuoka, Jun-ichirou Yasunaga.
- Organizer
  HTLV Conference 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] 機械学習を用いたHAM/TSP高リスクキャリアの同定と発症前状態バイオマーカー候補の探索2024
- Author(s)
  中岡慎治, 安永純一朗, 七條敬文, Rashid Md Ishtiak, 砂川純也, 松木彩星, 松岡雅雄
- Organizer
  日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] 成熟B細胞におけるPU.1の発現低下はリンパ腫の発症を誘導する2024
- Author(s)
  立津央, 遠藤慎也, 西村直, 豊田康祐, 菰原義弘, カレーラス・ジュアキム, 幸宏道, 七條敬文, 上野志貴子, 上野二菜, 平田真哉, 河野和, 野坂生郷, 宮岡雅, 中村直哉, 佐藤亜衣, 安藤潔, 満屋裕明, 赤司浩一, テネン・ダニエル, 安永純一朗, 松岡雅雄, 奥野豊
- Organizer
  第86回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] 霊長類宿主におけるPTLV-1付随タンパク質の進化的保存性および機能的多様性2024
- Author(s)
  フセインオサマ, マハグブモハメド, 七條敬文, 中川草, 三浦智行, 松岡雅雄, 安永純一朗
- Organizer
  日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] ほとんどが生検で確認されたコホートを利用した濾胞性リンパ腫の臨床的変化を診断するための評価ツールの調査(Investigation of assessment tools for diagnosing clinical transformation of follicular lymphoma using a cohort with most biopsy-confirmed patients)2024
- Author(s)
  立津央, 七條敬文, 樋口悠介, 野坂生郷, 安永純一朗
- Organizer
  第64回日本リンパ網内系学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] 当院におけるCNSリンパ腫に対するbusulfan thiothepa前処置での自家移植2024
- Author(s)
  樋口悠介, 立津央, 平野太一, 上野志貴子, 七條敬文, 竹崎達也, 黒田順一郎, 篠島直樹, 野坂生郷, 武笠晃丈, 安永純一朗
- Organizer
  第86回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] TGF-βによって誘導されるJunB/HBZの核内移行はATL発癌に重要である2024
- Author(s)
  張文怡, 七條敬文, 松岡雅雄, 安永純一朗
- Organizer
  日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] Characterizing immune cell shifts and clonal dynamics in anti-CCR4 monoclonal antibody-treated adult T-cell leukemia-lymphoma (ATL) patients2024
- Author(s)
  Osama Hussein, Kosuke Toyoda, Takafumi Shichijo, Masao Matsuoka, Jun-ichirou Yasunag
- Organizer
  HTLV Conference 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] 成人T細胞白血病に対するvalemetostatの宿主免疫への影響が治療反応性と関連する2024
- Author(s)
  岡本祐毅, 七條敬文, 遠藤慎也, 中村貴久, 渡辺信和, 松岡雅雄, 河北敏郎, 安永純一朗
- Organizer
  第86回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] TGF-β経路の活性化によるHTLV-1 bZIP factor/JunBタンパク質複合体の核内移行が発がんに寄与する(Nuclear translocation of HTLV-1 bZIP factor/JunB complex via TGF-β pathway activation is associated with ATL oncogenesis)2024
- Author(s)
  張文怡, 七條敬文, 松岡雅雄, 安永純一朗
- Organizer
  第83回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] Immune Cell Reconfiguration in Anti-CCR4 mAb Treated Adult T-cell Leukemia/Lymphoma (ATL) Patients2024
- Author(s)
  Osama Hussein, Kosuke Toyoda, Takafumi Shichijo, Masao Matsuoka, Jun-ichirou Yasunaga
- Organizer
  The 86th Annual Meeting of the Japanese Society of Hematology (JSH2024)
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] Evolution of Accessory Genes in Primate T-cell Leukemia Virus Type 12024
- Author(s)
  Osama Hussein, Mohamed Mahgoub, Takafumi Shichijo, So Nakagawa, Tomoyuki Miura, Masao Matsuoka, and Jun-ichirou Yasunaga
- Organizer
  The 71st Annual Meeting of the Japanese Society for Virology
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] Maladaptation to APOBEC3G is linked to HTLV-1 pathogenicity2024
- Author(s)
  Takafumi Shichijo, Jun-ichirou Yasunaga, Kei Sato, Kisato Nosaka, Kosuke Toyoda, Miho Watanabe, Wenyi Zhang, Yoshio Koyanagi, Edward Murphy, Roberta Bruhn, Ki-Ryang Koh, Hirofumi Akari, Terumasa Ikeda, Reuben Harris, Patrick Green, Masao Matsuoka.
- Organizer
  HTLV Conference 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] 成人T細胞白血病細胞におけるJun dimerization protein 2の意義2024
- Author(s)
  坂田亮, 豊田康祐, 七條敬文, 張文怡, 松岡雅雄, 安永純一朗
- Organizer
  日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] 診断に苦慮したATLL with HTLV-1-infected HRS-like cellsの1例2023
- Author(s)
  野坂生郷、立津央、樋口悠介、古川翔大、七條敬文、安永純一朗、川上史、三上芳喜、加留部謙之輔、松岡雅雄
- Organizer
  第63回日本リンパ網内系学会総会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] Prophylactic effect of tixagevimab-cilgavimab on COVID-19 infection in B-cell lymphoma2023
- Author(s)
  Kisato Nosaka, Hiro Tatetsu , Yusuke Higuchi, Takafumi Shichijo, Kazutaka Oda，Hirotomo Nakata, Jun ichirou Yasunaga, Masao Matsuoka
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] The Roles of Yin Yang 1 in the persistence of HTLV-12023
- Author(s)
  Tarig Salah, Jun-ichirou Yasunaga, Takafumi Shichijo, Masao Matsuoka.
- Organizer
  82nd Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] EBV-associated T and B cell lymphoproliferative disorder after autologous PBSCT for B cell lymphoma2023
- Author(s)
  Mikiko Izaki, Hiro Tatetsu, Kiho Yokoo, Hotaka Namie, Himari Kudo, Yusuke Higuchi, Takafumi Shichijo, Junichirou Yasunaga, Yoshiki Mikami, Kisato Nosaka, Masao Matsuoka
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] Impact of sensitivity to 2nd and 3rd line therapy in refractory/relapsed large B-cell lymphoma.2023
- Author(s)
  Hiro Tatetsu, Takafumi Shichijo, Kisato Nosaka, Yusuke Higuchi, Junichirou Yasunaga, Masao Matsuoka
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] Effect of CAR-T therapy on LBCL patients with progression disease (PD) just before infusion2023
- Author(s)
  平野太一，立津央，樋口悠介，七條敬文，上野志貴子，安永純一朗，野坂生郷，松岡雅雄
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303
[Presentation] TGF-β活性化によるHBZタンパクの局在変化はATL発がんに寄与する2023
- Author(s)
  張文怡, 安永純一朗, 七條敬文, 松岡雅雄
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15303

1. 松岡雅雄 (10244138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. TATETSU Hiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 安永純一朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 樋口悠介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

SHICHIJO TAKAFUMI 七條 敬文

Research Projects

Research Products

Co-Researchers

成人T細胞白血病の自然寛解のメカニズム解明と免疫療法への展開

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

TGF-β誘導性ATL特異的シグナルカスケードによる発がん機構解明と治療標的探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HTLV-1の適応進化不全によるATL発がん機構の解明と新規治療薬の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Stratagems of HTLV-1 for persistent infection and the resultant oncogenesis: Immune evasion and clonal expansion2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Validity of the criteria for clinical transformation of follicular lymphoma: analysis of a mostly biopsied cohort2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A dendritic cell-like transition of T cells is associated with spontaneous remission of adult T-cell leukemia-lymphoma2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Decreased PU.1 expression in mature B cells induces lymphomagenesis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vulnerability to APOBEC3G linked to the pathogenicity of deltaretroviruses.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Extranodal NK/T-cell lymphoma with localized relapse in bone marrow of lower leg detected using PET-CT2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] HTLV-1 bZIP factor-induced reprogramming of lactate metabolism and epigenetic status promote leukemic cell expansion.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prophylactic effect of tixagevimab-cilgavimab on COVID-19 infection and death in Japanese patients with B cell lymphoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Robust prognostic value of histologic transformation in patients with early progression of follicular lymphoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Significant response of patients with transformed follicular lymphoma with rapid disease progression to CAR-T therapy2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Presentation] CAR-T治療後に発症した末梢性T細胞リンパ腫2024

Author(s)

Organizer

Data Source

SHICHIJO TAKAFUMI 七條敬文