Ryota Sugawara 菅原涼太

Researcher Number	80978726
Affiliation (based on the past Project Information) *help	2023 – 2024: 愛知県医療療育総合センター発達障害研究所, 分子病態研究部, リサーチレジデント
Review Section/Research Field	Principal Investigator 0902:General internal medicine and related fields
Keywords	Principal Investigator 小頭症 / 巨脳症 / Rac1 / RAC / 神経細胞 / RAC3 / 低分子量G蛋白質 / 神経発達障害

Mechanism of macrocephaly and microcephaly caused by genetic mutations in RAC1 small GTPasePrincipal Investigator
- Principal Investigator
  
  Ryota Sugawara
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0902:General internal medicine and related fields
- Research Institution
  Institute for Developmental Research Aichi Developmental Disability Center

All 2025 2024

All Journal Article

[Journal Article] A p.N92K variant of the GTPase RAC3 disrupts cortical neuron migration and axon elongation2025
- Author(s)
  Sugawara Ryota、Hamada Keisuke、Ito Hidenori、Scala Marcello、Ueda Hiroshi、Tabata Hidenori、Ogata Kazuhiro、Nagata Koh-ichi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 301 Issue: 4 Pages: 108346-108346
- DOI
  10.1016/j.jbc.2025.108346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07309, KAKENHI-PROJECT-22K06579, KAKENHI-PROJECT-23K19577
[Journal Article] The p.R66W Variant in RAC3 Causes Severe Fetopathy Through Variant-Specific Mechanisms2024
- Author(s)
  Sugawara Ryota、Ito Hidenori、Tabata Hidenori、Ueda Hiroshi、Scala Marcello、Nagata Koh-ichi
- Journal Title
  
  Cells
  
  Volume: 13 Issue: 23 Pages: 2032-2032
- DOI
  10.3390/cells13232032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24310, KAKENHI-PROJECT-21K07309, KAKENHI-PROJECT-22K06579, KAKENHI-PROJECT-22K19498, KAKENHI-PROJECT-23K19577
[Journal Article] Expression analysis of type I ARF small GTPases ARF1-3 during mouse brain development2024
- Author(s)
  Matsuki Tohru、Hamada Nanako、Ito Hidenori、Sugawara Ryota、Iwamoto Ikuko、Nakayama Atsuo、Nagata Koh-ichi
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 51 Issue: 1 Pages: 106-106
- DOI
  10.1007/s11033-023-09142-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K19577, KAKENHI-PROJECT-23K07284, KAKENHI-PROJECT-20K08200, KAKENHI-PROJECT-20K08224, KAKENHI-PROJECT-23K24310, KAKENHI-PROJECT-22K19498, KAKENHI-PROJECT-24K10947

1. 田畑秀典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 永田浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ryota Sugawara 菅原涼太

Research Projects

Research Products

Co-Researchers

Mechanism of macrocephaly and microcephaly caused by genetic mutations in RAC1 small GTPasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] A p.N92K variant of the GTPase RAC3 disrupts cortical neuron migration and axon elongation2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The p.R66W Variant in RAC3 Causes Severe Fetopathy Through Variant-Specific Mechanisms2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression analysis of type I ARF small GTPases ARF1-3 during mouse brain development2024

Author(s)

Journal Title

DOI

Data Source

Ryota Sugawara 菅原 涼太

Research Projects

Research Products

Co-Researchers

Mechanism of macrocephaly and microcephaly caused by genetic mutations in RAC1 small GTPasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] A p.N92K variant of the GTPase RAC3 disrupts cortical neuron migration and axon elongation2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The p.R66W Variant in RAC3 Causes Severe Fetopathy Through Variant-Specific Mechanisms2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression analysis of type I ARF small GTPases ARF1-3 during mouse brain development2024

Author(s)

Journal Title

DOI

Data Source

Ryota Sugawara 菅原涼太