HOJO Hiroshi 北條博史

… Alternative Names

北條博史ホウジョウヒロシ

北条博史ホウジョウヒロフミ

北絛博史

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Researcher Number	90004621
Other IDs
Affiliation (based on the past Project Information) *help	2006 – 2007: 昭和薬科大学, 薬学部, 教授 2002 – 2004: 昭和薬科大学, 薬学部, 教授 1997 – 1999: 昭和薬科大学, 薬学部, 教授 1995: 東北大学, 薬学部, 助教授 1993: 東北大学, 薬学部, 助教授 1987 – 1989: 東北大学, 薬学部, 助教授
Review Section/Research Field	Principal Investigator Biological pharmacy / Environmental pharmacy / Environmental pharmacy
Keywords	Principal Investigator 肝障害 / 四塩化炭素 / インターロイキン-6 / インターロイキン6 / Liver injury / ラット / サイトカイン / dexamethasone / IL-6 / TNFα … More / IL-1α / 中皮細胞 / PGE_2 / Mesothelial cell / 膀胱癌 / インターロイキン-1 / 腫瘍壊死因子 / TNF / 自己増殖因子 / デキサメサゾン / エンドトキシン / carbon tetracloride / interleukin-6 / cytokine / rat / 漿膜 / 奬膜 / プロスタグランジンE_2 / 腹腔内 / lipopolysaccharide / マクロファージ / Carbon tetrachlorid / serous membrane / 炎症性因子 / インターロイキン-1α / 保護タンパク質 / ヘムオキシゲナーゼ-1 / 腹腔内細胞 / ヘムオキシゲナーゼ1 / STAT3 / Carbon tetrachloride / Interleukin-6 / Inflammatory factor / Interleukin-1a / Protective protein / Heme oxygenase-1 … More Except Principal Investigator モノクローナル抗体 / モノクロ-ナル抗体 / C-erbB-2 / 細胞増殖関連抗原 / 制がん剤 / リポソ-ム / 腫瘍壊死因子(TNF) / 血管透過性 / 海洋微生物 / ジアシルグリセロール / ゴニオドミンA / ユージストミン / アクチン / 細胞毒性 / 細胞運動 / ヒト膀胱がん / がん尿診断 / がん抗原不均 / 性-マウス増殖関連抗原 / アドリアマイシン / 抗体修飾リポソーム / ヒトc-erbB-2タンパク / 甲状腺がん / 前立腺がん / ラットCD3 / ケモイミュノリポソーム(CIL) / gp125抗原 Less

Mechanism of interleukin-6 induction by intraperitoneal administration of carbon tetrachloride and its effect on hepatic injuryPrincipal Investigator
- Principal Investigator
  
  HOJO Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Showa Pharmaceutical University
Mechanisms for the administration route-dependent induction of IL-6 by carbon tetrachloride and the suppression of liver injury by IL-6Principal Investigator
- Principal Investigator
  
  HOJO Hiroshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Showa Pharmaceutical University
MOLECULAR MECHANISM OF INFLAMMATORY AND IMMUNOLOGICAL FACTORS INVOLVED IN DRUG-INDUCED LIVER INJURYPrincipal Investigator
- Principal Investigator
  
  HOJO Hiroshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Showa Pharmaceutical University
ラット膀胱癌細胞におけるTNFおよびIL-1αの産生調節機構と阻害因子の研究Principal Investigator
- Principal Investigator
  
  北條博史
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
海洋微生物に含まれる抗腫瘍性成分の化学および生物学的研究
- Principal Investigator
  
  大泉康
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
モノクロ-ナル抗体のがん診断、治療への応用
- Principal Investigator
  
  橋本嘉幸
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
モノクローナル抗体のがん診断、治療への応用
- Principal Investigator
  
  橋本嘉幸
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
モノクローナル抗体のがん診断, 治療への応用
- Principal Investigator
  
  橋本嘉幸
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University

All 2008 2007 2003 2002

All Journal Article

[Journal Article] Interleukin-6 production by peritoneal mesothelial cells and its regulation by inflammatory factors in rats administered carbon tetrachloride intraperitoneally2008
- Author(s)
  K.Yamaji, K.Ohnishi, R.Zuinen, Y.Ochiai, T.Chikuma, H.Hojo
- Journal Title
  
  Toxicology and Applied Pharmacology 226
  
  Pages: 38-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590120
[Journal Article] Axonal transports of tripeptidyl peptidase II in rat sciatic nerves2007
- Author(s)
  T.Chikuma, M.Shimizu, Y.Tsuchiya, T.Kato, H.Hojo
- Journal Title
  
  Neurochemistry International 50
  
  Pages: 236-242
- Data Source
  KAKENHI-PROJECT-18590120
[Journal Article] 4-Hydroxy-2-nonenal-modified glycelaldehyde-3-phosphate dehydrogenase is degraded by cathepsin G2007
- Author(s)
  Y.Tsuchiya, Y.Okuno, K.Hishinuma, A.Ezaki, G.Okada, M.Yamaguchi, T.Chikuma, H.Hojo
- Journal Title
  
  Free Radical Biology & Medicine 43
  
  Pages: 1604-1615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590120
[Journal Article] Early induced, high-level interleukin-6 expression in the rat peritoneal cavity into which a hepatotoxicant carbon tetrachloride was administered2007
- Author(s)
  R.Zuinen, K.Yamaji, M.Aoki, T.Chikuma, H.Hojo
- Journal Title
  
  Toxicology Letters
- Data Source
  KAKENHI-PROJECT-18590120
[Journal Article] Conformational change of glycelaldehyde-3-phosphate dehydrogenase induced by acetylleucine chloromethyl ketone is followed by unique enzyatic degrada2003
- Author(s)
  M Yamaguchi, Y Tsuchiya, K Hishinuma, T Chikuma, H Hojo
- Journal Title
  
  Biological Pharmaceutical Bulletin 26
  
  Pages: 1648-1651
- Data Source
  KAKENHI-PROJECT-14572113
[Journal Article] production of interleukin-6 and its implication in rats after subcutaneous injection of carbon tetrachloride2002
- Author(s)
  H Hojo, T Kasakura, R Zuinen, M Aoki, M Yamaguchi, T Chikuma, M Sato
- Journal Title
  
  J of Health Science 48
  
  Pages: 1-6
- NAID
  110003641460
- Data Source
  KAKENHI-PROJECT-14572113
[Journal Article] Degradation of glyceraldehydes-3-phosphate dehydrogenase induced by acetyl-leucine chloromethyl ketone in U937 cells.2002
- Author(s)
  M Yamaguchi, Y Tsuchiya, T Chikuma, H Hojo
- Journal Title
  
  Biochemical Pharmacology 63
  
  Pages: 1857-1862
- Data Source
  KAKENHI-PROJECT-14572113

1. 橋本嘉幸 (90072412)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 益子高 (30157200)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. YAMAGUCHI Mitsune (90276634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. YAWATA Ayako (00384636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 大泉康 (00006355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 松永公浩 (90222306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 古川賢一 (20165468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 中畑則道 (60045804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HOJO Hiroshi 北條 博史

北條 博史 ホウジョウ ヒロシ

北条 博史 ホウジョウ ヒロフミ

北絛 博史

Research Projects

Research Products

Co-Researchers

Mechanism of interleukin-6 induction by intraperitoneal administration of carbon tetrachloride and its effect on hepatic injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms for the administration route-dependent induction of IL-6 by carbon tetrachloride and the suppression of liver injury by IL-6Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MOLECULAR MECHANISM OF INFLAMMATORY AND IMMUNOLOGICAL FACTORS INVOLVED IN DRUG-INDUCED LIVER INJURYPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ラット膀胱癌細胞におけるTNFおよびIL-1αの産生調節機構と阻害因子の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

海洋微生物に含まれる抗腫瘍性成分の化学および生物学的研究

Principal Investigator

Project Period (FY)

Research Category

Research Institution

モノクロ-ナル抗体のがん診断、治療への応用

Principal Investigator

Project Period (FY)

Research Category

Research Institution

モノクローナル抗体のがん診断、治療への応用

Principal Investigator

Project Period (FY)

Research Category

Research Institution

モノクローナル抗体のがん診断, 治療への応用

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] Interleukin-6 production by peritoneal mesothelial cells and its regulation by inflammatory factors in rats administered carbon tetrachloride intraperitoneally2008

Author(s)

Journal Title

Data Source

[Journal Article] Axonal transports of tripeptidyl peptidase II in rat sciatic nerves2007

Author(s)

Journal Title

Data Source

[Journal Article] 4-Hydroxy-2-nonenal-modified glycelaldehyde-3-phosphate dehydrogenase is degraded by cathepsin G2007

Author(s)

Journal Title

Data Source

[Journal Article] Early induced, high-level interleukin-6 expression in the rat peritoneal cavity into which a hepatotoxicant carbon tetrachloride was administered2007

Author(s)

Journal Title

Data Source

[Journal Article] Conformational change of glycelaldehyde-3-phosphate dehydrogenase induced by acetylleucine chloromethyl ketone is followed by unique enzyatic degrada2003

Author(s)

Journal Title

Data Source

[Journal Article] production of interleukin-6 and its implication in rats after subcutaneous injection of carbon tetrachloride2002

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Degradation of glyceraldehydes-3-phosphate dehydrogenase induced by acetyl-leucine chloromethyl ketone in U937 cells.2002

Author(s)

Journal Title

Data Source

HOJO Hiroshi 北條博史

北條博史ホウジョウヒロシ

北条博史ホウジョウヒロフミ

北絛博史