NUMAZAWA Mitsuteru 沼澤光輝

… Alternative Names

沼澤光輝ヌマザワミツテル

沼沢光輝ヌマザワミツテル

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Researcher Number	90006338
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2010: 東北薬科大学, 薬学部, 教授 2000 – 2005: 東北薬科大学, 薬学部, 教授 1996 – 1998: 東北薬科大学, 薬学部, 教授 1991 – 1993: 東北薬科大学, 薬学部, 教授 1986 – 1989: 東北薬科大学, 薬学部, 教授
Review Section/Research Field	Principal Investigator Biological pharmacy / Laboratory medicine / 医薬分子機能学 / Biological pharmacy Except Principal Investigator Physical pharmacy / Physical pharmacy
Keywords	Principal Investigator アロマターゼ / 阻害剤 / Aromatase / マススペクトロメトリー / 芳香核化反応 / ヒト胎盤ミクロゾーム / 構造活性相関 / ガスクロマトグラフィー / 19位酸素化反応 / 乳ガン化学療法剤 … More / 自殺基質 / 拮抗阻害剤 / アロマタ-ゼ / 3-デオキシステロイド / 乳がん / 3-Deoxy steroid / Gas chromatography-mass spectrometry / Inhibitor / Structure-activity relationship / 3-デオキシアンドロゲン / 16alpha,19-ジヒドロキシアンドロゲン / アイソトープ標識内標物質 / 血中濃度 / 胎児-胎盤系 / 妊婦 / ガスクロストグラフィー / キネティックス / 二重標識阻害剤 / 不可逆的結合 / ラジオメトリックアッセイ / 4-ヒドロキシアンドロステンジオン / アンドロスト-4-エン-7,17-ジオン / 6-アルキルアンドロステンジオン / ヒト胎盤ミクロゾ-ム / アンドロストー4ーエンー3,6,17ートリオン / 3ーデオキシステロイド / 6α,7αーシクロプロパンステロイド / Human Placental Microsomes / Suicide Substrate / Competitive Inhibitor / Double-Labeled Inhibitor / Irreversible Binding / Radiometric Assay / Structure Activity Relationship / アロマターゼ阻害剤 / 6-アルキルステロイド / 芳香核化 / 19-酸素化 / 6-アルキルアンドロゲン / Aromatase Inhibitor / 6-Alkyl steroid / Aromatization / 19-Oxygenation / Gas chromatography / Mass spectrometry / Breast cancer / スルファターゼ / ガスクロマトグラフイー-マススペクトロメトリー / スルファモイル基 / アンドロステンジオン / ガスクロマトグラフィー-マススペクトロメトリー / 4'-メトキシアルキル基 / ホルモン療法 / エストロゲンスルファターゼ / 多機能性分子 / スルファメート / Sulfatase / Sulfamoylphenyl / Androstenedione / 乳がん治療薬 / 水酸化反応 / 立体化学 / 炭素-炭素切断反応 / 炭素-炭素結合切断 / 不活性化機構 / 阻害活性 / 19-置換3-デオキシアンドロゲン / 重水素標識 / 同位体効果 / トリチウム標識 / Anti-breast cancer agent / Hydroxylation / Stereochemistry / Suicidal substrate / Carbon -carbon bond cleavage reaction / エストリオ-ル / 3ーデオキシアンドロゲン / 16α,19ージヒドロキシアンドロゲン / 血圧上昇物質 / 重水素標識体 / ガスクロマトグラフィ-ーマススペクトロメトリ- / 16α,19-ジヒドロキシアンドロゲン / ガスクロマトグラフィ--マススペクトロメトリ- / エストリオール / 生合成経路 / 生合成中間体 / キネティック定数 / Estriol / Competitive inhibitor / 3-Deoxyandrogen / 16alpha;19-Dihydroxy-androgen / Hypertensinogenic agent / Deuterated compound … More Except Principal Investigator 乳がん / エストロゲン / オルトキノン / フェナジン誘導体 / 質量分析 / 分析化学 / エストロゲンオルトキノン / 定量分析 / LC-MS / LC-ESI-MS/MS / ヘムタンパク / カテコールエストロゲン / 高速液体クロマトグラフィー / ラジオイムノアッセイ / 抱合型エテトロゲン / エキレニン / 乳癌 / ゴナドトロピン / 抱合型エストロゲン / 電気化学検出高速液体クロマトグラフィー / 芳香核水酸化酵素 / エストロゲンレセプター / エストロゲン依存性腫瘍 / Catechol estrogen / High-performance liquid chromatography / Radioimmunoassay / Comjugated estrogen / Equilenin / Breast cancer Less

Development of the analytical method for estrogen-o-quinones and its application to the study on the initiation mechanism of human breast cancer
- Principal Investigator
  
  YAMASHITA Kouwa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tohoku Pharmaceutical University
Study on aromatase reaction mechanism using the inhibitors as probesPrincipal Investigator
- Principal Investigator
  
  NUMAZAWA Mitsuteru
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku Pharmaceutical University
Development of Anti-Breast Cancer Agents Having Diverse FunctionsPrincipal Investigator
- Principal Investigator
  
  NUMAZAWA Mitsuteru
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Tohoku Pharmaceutical University
Aromatase Reaction of Suicide Substrates of Aromatase and Their Inactivation Mechanisms.Principal Investigator
- Principal Investigator
  
  NUMAZAWA Mitsuteru
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku College of Pharmacy
阻害剤をプローブとするアロマターゼの解媒機能解析Principal Investigator
- Principal Investigator
  
  沼沢光輝
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku Pharmaceutical University
胎児-胎盤系で産生する16alpha、19-水酸化ステロイドの動態Principal Investigator
- Principal Investigator
  
  沼沢光輝
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tohoku Pharmaceutical University
ACTIVATION MECHANISM OF SUICIDE SUBSTRATE OF AROMATASEPrincipal Investigator
- Principal Investigator
  
  NUMAZAWA Mitsuteru
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  TOHOKU COLLEGE OF PHARMACY
Mechanistic Study of Estriol Biosynthesis and Its InhibitorPrincipal Investigator
- Principal Investigator
  
  NUMAZAWA Mitsuteru
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku College of Pharmacy
The Metabolic Disposition of Catechol Estrogens and Its Significance in Clinical Chemistry
- Principal Investigator
  
  NAMBARA Toshio
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  TOHOKU UNIVERSITY

All 2013 2012 2011 2010 2005 2004 2003

All Journal Article Presentation

[Journal Article] Assay of labile estrogen o-quinones, a potent carcinogenic molecular species, by high performance liquid chromatographyelectrospray ionization mass spectrometry with phenazine derivatization2010
- Author(s)
  K. Yamashita, A. Masuda, Y. Hoshino, S.Komatsu, M. Numazawa
- Journal Title
  
  J. Steroid Biochem. Mol. Biol
  
  Volume: 119 Pages: 141-148
- Data Source
  KAKENHI-PROJECT-22590041
[Journal Article] Structure-Activity Relationships of 2α-Substituted Androstenedione Analogs as Aromatase Inhibitors and Their Aromatization Reactions.2005
- Author(s)
  Mitsuteru Numazawa, et al.
- Journal Title
  
  J.Steroid Biochem.Molec.Biol. 97
  
  Pages: 353-359
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Aromatase Reaction of 3-Deoxyandrogens : Steric Mode of the C-19 Oxygenation and Clevage of the C_<10>-C_<19> Bond by Human Placental Aromatase.2005
- Author(s)
  沼沢光輝
- Journal Title
  
  Biochemistry 44
  
  Pages: 10839-10845
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Structure-Activity Relationships of 2α-Substituted Androstenedione Analogs as Aromatase Inhibitors and Their Aromatization Reactions.2005
- Author(s)
  沼沢光輝
- Journal Title
  
  J. Steroid Biochem. Molec. Biol. 97
  
  Pages: 353-359
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Gas chromatography-mass spectrometric analysis of oxidative reactions of [19,19-^2H_2]19-hydroxy-3-deoxy androgens by placental aromatase. Absence of a deuterium-isotope effect2005
- Author(s)
  沼沢光輝
- Journal Title
  
  Steroids 70
  
  Pages: 831-839
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Gas Chromatography-Mass Spectrometric Analysis of Oxidative Reactions of [19,19^<-2>H_2] 19-Hydroxy-3-deoxy Androgens by Placental Aromatase. Absence of a Deuterium-Isotope Effect.2005
- Author(s)
  Mitsuteru Numazawa, et al.
- Journal Title
  
  Steroids 70
  
  Pages: 831-839
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Structure-activity relationships of 2-,4-, or 6-substituted estrogens as aromatase inhibitors2005
- Author(s)
  沼沢光輝
- Journal Title
  
  J.Steroid Biochem.Molec.Biol 96
  
  Pages: 51-58
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Structure-activity relationships of 2α-substituted androstenedione analogs as aromatase inhibitors and their aromatization reactions2005
- Author(s)
  沼沢光輝
- Journal Title
  
  J.Steroid Biochem.Molec.Biol 97
  
  Pages: 353-359
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Structure Activity Relationships of 2-,4-, or 6-Substituted Estrogens as Aromatase Inhibitors.2005
- Author(s)
  沼沢光輝
- Journal Title
  
  J. Steroid Biochem. Molec. Biol. 96
  
  Pages: 51-58
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Aromatase Reaction of 3-Deoxy Androgens : Steric Mode of the C-19 Oxygenation and Clevage of the C_<10>-C_<19> Bond by Human Placental Aromatase.2005
- Author(s)
  Mitsuteru Numazawa, et al.
- Journal Title
  
  Biochemistry 44
  
  Pages: 10839-10882
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Gas Chromatography-Mass Spectrometric Analysis of Oxidative Reactions of [19, 19-^2H_2]19-Hydroxy-3-deoxy Androgens by Placental Aromatase. Absence of a Deuterium-Isotope Effect.2005
- Author(s)
  沼沢光輝
- Journal Title
  
  Steroids 70
  
  Pages: 831-839
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Structure-Activity Relationships of 2-,4, or 6-Substituted Estrogens as Aromatase Inhibitors.2005
- Author(s)
  Mitsuteru Numazawa, et al.
- Journal Title
  
  J Steroid Biochem.Molec.Biol. 96
  
  Pages: 51-58
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Aromatase reaction of 3-deoxyandrogens : steric mode of the C-19 oxygenation and cleavage of the C_<10>-C_<19> bond by human placental aromatase2005
- Author(s)
  沼沢光輝
- Journal Title
  
  Biochemistry 44
  
  Pages: 10839-10845
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] C(10)-C(19) Bond Cleavage Reaction of 19-oxygenated Androst-4-ene-3,6-dione Steroids under Various Conditions.2004
- Author(s)
  沼沢光輝
- Journal Title
  
  Chem. Pharm. Bull. 52
  
  Pages: 983-985
- NAID
  110003615701
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Stereochemistry of NaBH_4 reduction of a 19-carbonyl group of 3-deoxy androgens. Synthesis of [19R-^3 H]-labeled aromatase inhibitors having a 19-hydroxy group2004
- Author(s)
  沼澤光輝
- Journal Title
  
  Chem.Pharm.Bull. 52
  
  Pages: 722-726
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Synthesis and biochemical properties of 6-brompandrostenedione derivatives with a 2,2-dimethyl or 2-methyl group as aromatase inhibitors2004
- Author(s)
  沼澤光輝
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 1878-1882
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] C(10)-C(19) Bond Cleavage Reaction of 19-Oxygenated Androst-4-ene- 3,6-done Steroids under Various Conditions.2004
- Author(s)
  Mitsuteru Numazawa, et al.
- Journal Title
  
  Chem.Pharm.Bull. 52
  
  Pages: 983-985
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] C(10)-C(19) Bond cleavage reaction of 19-oxygenated androst-4-ene-3,6-dione steroids under various conditions2004
- Author(s)
  沼澤光輝
- Journal Title
  
  Chem.Pharm.Bull. 52
  
  Pages: 983-985
- NAID
  110003615701
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Synthesis and Biochemical Properties of 6-Bromoandrostenedione Derivatives with a 2,2-Dimethyl or 2-Methyl Group as Aromatase Inhibitors.2004
- Author(s)
  Mitsuteru Numazawa, et al.
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 1878-1882
- NAID
  110003608716
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Stereochemistry of NaBH_4 Reduction of a 19-Carbonyl Group of 3-Deoxy Androgens. Synthesis of [19S-^3H]- and [19R-^3H]-Labeled Aromatase Inhibitors Having a 19-Hydroxy Group.2004
- Author(s)
  沼沢光輝
- Journal Title
  
  Chem. Pharm. Bull. 52
  
  Pages: 722-726
- NAID
  110003615648
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Stereochemistry of NaBH_4 Reduction of a 19-Carbonyl Group of 3-Deoxy Androgens. Synthesis of [19S^<-3>H]-and [19R^<-3>H]-Labeled Aromatase Inhibitors Having a 19-Hydroxy Group.2004
- Author(s)
  Mitsuteru Numazawa, et al.
- Journal Title
  
  Chem.Pharm.Bull. 52
  
  Pages: 722-726
- NAID
  110003615648
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Synthesis and Biochemical Properties of 6-Bromoandrostenedione Derivatives with a 2,2-Dimethyl or 2-Methyl Group as Aromatase Inhibitors.2004
- Author(s)
  沼沢光輝
- Journal Title
  
  Biol. Pharm. Bull 52
  
  Pages: 1878-1882
- NAID
  110003608716
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Structure-Activity Relationships of 3-Deoxy Androgens as Aromatase Inhibitors. Synthesis and Biochemical Studies of 4-Substituted 4-ene and 5-ene Steroids.2003
- Author(s)
  沼沢光輝
- Journal Title
  
  Steroids 68
  
  Pages: 533-542
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Probing the Active Site of Aromatase with 2-Methyl-substituted Androstenedione Analogs.2003
- Author(s)
  Mitsuteru Numazawa, et al.
- Journal Title
  
  Steroids 68
  
  Pages: 503-513
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Structure-Activity Relationships of 3-Deoxy Androgens as Aromatase Inhibitors. Synthesis and Biochemical Studies of 4-Substituted 4-ene and 5-ene Steroids.2003
- Author(s)
  Mitsuteru Numazawa, et al.
- Journal Title
  
  Steroids 68
  
  Pages: 533-542
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Analysis of Reversibli Inhibition of 16α-Hydroxyandrostenedione Aromatization in Human Placental Microsomes by Suicide Substrates of Androstenedione Aromatization.2003
- Author(s)
  沼沢光輝
- Journal Title
  
  Biol. Pharm. Bull. 26
  
  Pages: 890-892
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Probing the Active Site of Aromatase with 2-Methyl-substituted Androstenedione Analogs.2003
- Author(s)
  沼沢光輝
- Journal Title
  
  Steroids 68
  
  Pages: 503-513
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Journal Article] Analysis of Reversible Inhibition of 16α-Hydroxyandrostenedione Aromatization in Human Placental Microsomes by Suicide Substrates of Androstenedione Aromatization.2003
- Author(s)
  Mitsuteru Numazawa, et al.
- Journal Title
  
  Biol.Pharm.Bull. 26
  
  Pages: 890-892
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590066
[Presentation] LC-ESI-MS/MS法による水酸化ステロイドのメタボローム解析(V)安定同位体標識カテコールエストロゲン－GSH付加体の合成－2013
- Author(s)
  山下幸和、近藤恵美、白取未希、小松祥子、加藤　創、大野賢一、沼澤光輝
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590041
[Presentation] LC-ESI-MS/MS法による水酸化ステロイドのメタボローム解析(VI)－ステロイド硫酸抱合体の定量法の最適化－2013
- Author(s)
  小松祥子、齋藤彩夏、榊　克教、山下幸和、沼澤光輝
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590041
[Presentation] LC-ESI-MS/MS法による水酸化ステロイドのメタボローム解析(V)安定同位体標識カテコールエストロゲン-GSH 付加体の合成2013
- Author(s)
  山下幸和、近藤恵美、白取未希、小松祥子、加藤創、大野賢一、沼澤光輝
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-22590041
[Presentation] LC-ESI-MS/MSによる水酸化ステロイドのメタボロム解析(IV)27 ステロイドの一斉分析2012
- Author(s)
  山下幸和、小松祥子、加藤創、大野賢一、沼澤光輝、本間誠次郎
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22590041
[Presentation] Use of proton-affinitive derivatization in HPLC-positive-ESI-MS analysis of biologically important carboxylic acids2012
- Author(s)
  Hajime Kato, Shin Mitsuzuka, Kouwa Yamashita, Mitsuteru Numazawa
- Organizer
  19th International Mass Spectrometry Conference
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590041
[Presentation] Use of proton-affinitive derivatization in HPLC-ESI-MS analysis of biologically important carboxylic acids2012
- Author(s)
  H. Kato, S. Mitsuzuka, K. Yamashita, M. Numazawa
- Organizer
  19^<th>International Mass Spectrometry Conference
- Place of Presentation
  Kyoto
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22590041
[Presentation] LC-ESI-MS/MS によるアロマターゼ活性測定法の開発および従来法との比較2012
- Author(s)
  小松祥子、鈴木直樹、高橋透、山下幸和、沼澤光輝
- Organizer
  第51回日本薬学会東北支部大会
- Place of Presentation
  青森
- Year and Date
  2012-10-07
- Data Source
  KAKENHI-PROJECT-22590041
[Presentation] LC-ESI-MS/MS法による水酸化ステロイドのメタボローム解析(IV)27ステロイドの一斉分析2012
- Author(s)
  山下幸和、小松祥子、加藤創、大野賢一、沼澤光輝、本間誠次郎
- Organizer
  日本薬学会第年会
- Place of Presentation
  札幌(北海道大学)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22590041
[Presentation] LC-ESI-MS/MSによるアロマターゼ活性測定法の開発および従来法との比較2012
- Author(s)
  小松祥子、鈴木直樹、高橋　透、山下幸和、沼澤光輝
- Organizer
  第51回日本薬学会東北支部大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-22590041
[Presentation] エストロゲンオルトキノンによるタンパク修飾(I)-L-Cys, N-Ac-L-Cys 及び GSH-共有結合体の調製とカテコール/キノン平衡2011
- Author(s)
  白取未希、加藤創、山下幸和、沼澤光輝
- Organizer
  第50回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PROJECT-22590041
[Presentation] An approach to the microdetermination of labile estrogen o-quinones by liquid chromatographyelectrospray ionization tandem mass spectrometry2010
- Author(s)
  K. Yamashita, S. Komatsu, A. Masuda, M. Numazawa
- Organizer
  58^<th>ASMS Confererence
- Place of Presentation
  Salt Lake City, USA
- Year and Date
  2010-05-25
- Data Source
  KAKENHI-PROJECT-22590041

1. MUTSUMI Ayako

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. YAMADA Keiko

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. YOSHIMURA Akiko

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. WATARI Yoko

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 橘美伊

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YAMASHITA Kouwa (80382670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
7. OHNO Ken-ichi (20347272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. KATO Hajime (80584458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
9. KOMATSU Sachiko (00438566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
10. SATOH Satoshi (70215789)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAGAOKA Masao (00104084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NAMBARA Toshio (30004534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HONJO Hideo (30110852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MIYABO Susumu (70019884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YOSHIZAWA Itsuo (80088864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TOHMA Masahiko (30001043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ANDO Momoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HANDA Wakako

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TAKAHASHI Madoka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. HOSHI Kumiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 押部真里子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NUMAZAWA Mitsuteru 沼澤 光輝

沼澤 光輝 ヌマザワ ミツテル

沼沢 光輝 ヌマザワ ミツテル

Research Projects

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Co-Researchers

Development of the analytical method for estrogen-o-quinones and its application to the study on the initiation mechanism of human breast cancer

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Study on aromatase reaction mechanism using the inhibitors as probesPrincipal Investigator

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Development of Anti-Breast Cancer Agents Having Diverse FunctionsPrincipal Investigator

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Aromatase Reaction of Suicide Substrates of Aromatase and Their Inactivation Mechanisms.Principal Investigator

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阻害剤をプローブとするアロマターゼの解媒機能解析Principal Investigator

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胎児-胎盤系で産生する16alpha、19-水酸化ステロイドの動態Principal Investigator

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ACTIVATION MECHANISM OF SUICIDE SUBSTRATE OF AROMATASEPrincipal Investigator

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Mechanistic Study of Estriol Biosynthesis and Its InhibitorPrincipal Investigator

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The Metabolic Disposition of Catechol Estrogens and Its Significance in Clinical Chemistry

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[Journal Article] Assay of labile estrogen o-quinones, a potent carcinogenic molecular species, by high performance liquid chromatographyelectrospray ionization mass spectrometry with phenazine derivatization2010

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[Journal Article] Structure-Activity Relationships of 2α-Substituted Androstenedione Analogs as Aromatase Inhibitors and Their Aromatization Reactions.2005

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[Journal Article] Aromatase Reaction of 3-Deoxyandrogens : Steric Mode of the C-19 Oxygenation and Clevage of the C_<10>-C_<19> Bond by Human Placental Aromatase.2005

Author(s)

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Description

Data Source

[Journal Article] Structure-Activity Relationships of 2α-Substituted Androstenedione Analogs as Aromatase Inhibitors and Their Aromatization Reactions.2005

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[Journal Article] Gas chromatography-mass spectrometric analysis of oxidative reactions of [19,19-^2H_2]19-hydroxy-3-deoxy androgens by placental aromatase. Absence of a deuterium-isotope effect2005

NUMAZAWA Mitsuteru 沼澤光輝

沼澤光輝ヌマザワミツテル

沼沢光輝ヌマザワミツテル