Yoshida Takemi 吉田武美

… Alternative Names

YOSHIDA Takemi 吉田武美

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Researcher Number	90006354
Other IDs
Affiliation (Current)	2022: 昭和大学, 薬学部, 名誉教授
Affiliation (based on the past Project Information) *help	2011 – 2012: 昭和大学, 薬学部, 名誉教授 2009 – 2010: Showa University, 薬学部, 教授
Review Section/Research Field	Principal Investigator Environmental pharmacy
Keywords	Principal Investigator マイクロRNA / 肝毒性 / 精巣毒性 / 胎盤毒性 / 毒性発現機構 / ガス状物質 / 一酸化炭素 / 硫化水素 / Nrf2 / 肝傷害 / 動脈硬化 / 血管平滑筋細胞

Mutual regulation of physiological gases by xenobioticsPrincipal Investigator
- Principal Investigator
  
  YOSHIDA Takemi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental pharmacy
- Research Institution
  Showa University
薬毒物の毒性発現におけるマイクロRNAの変動解析とその安全性評価への応用Principal Investigator
- Principal Investigator
  
  吉田武美
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental pharmacy
- Research Institution
  Showa University

All 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Microarray analysis of 6-mercaptopurine-induced-toxicity-related genes and microRNAs in the rat placenta2013
- Author(s)
  Taki K, Fukushima T, Ise R, Horii I, Yoshida T
- Journal Title
  
  J Toxicol Sci
  
  Volume: 38(1) Pages: 159-167
- NAID
  10031138739
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/23358152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] Cross-talk between constitutive androstane receptor and hypoxia-inducible factor in the regulation of gene expression.2013
- Author(s)
  Shizu R, Shindo S, Yoshida T and Numazawaa S
- Journal Title
  
  Toxicol Lett
  
  Volume: 219 Pages: 143-150
- DOI
  10.1016/j.toxlet.2013.03.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590143, KAKENHI-PROJECT-23659068
[Journal Article] Redox-Sensitive Transcription Factor Nrf2 Regulates Vascular Smooth Muscle Cell Migration and Neointimal Hyperplasia.2013
- Author(s)
  Ashino T, Yamamoto M, Yoshida T, Numazawa S
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 33 Pages: 760-768
- DOI
  10.1161/atvbaha.112.300614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590143, KAKENHI-PROJECT-23659068, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790785
[Journal Article] MicroRNA-122 down-regulation is involved in phenobarbital-mediated activation of the constitutive androstane receptor2013
- Author(s)
  Shizu R, Shindo S, Yoshida T and Numazawa S
- Journal Title
  
  PLoS One
  
  Volume: 7
- DOI
  10.1371/annotation/75898a72-dfcb-4002-b749-8c04d78ba6e1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590143, KAKENHI-PROJECT-23659068
[Journal Article] Involvement of microRNA in the induction of drug-metabolizing enzymes2012
- Author(s)
  Shizu R, Numazawa S, Yoshida T
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 132(3) Pages: 311-318
- NAID
  130001872026
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22382835
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] Possible involvement of transient receptor potential channels in electrophile-induced insulin secretion from RINm5F cells.2012
- Author(s)
  Numazawa S, Takase M, Ahiko T, Ishii M, Shimizu S, Yoshida T.
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 35 Pages: 346-354
- NAID
  130001872315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] Involvement of interleukin-1 in lead nitrate-induced hypercholesterolemia in mice2012
- Author(s)
  Kojima M, Ashino T, Yoshida T, Iwakura Y, Degawa M
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 35(2) Pages: 246-250
- NAID
  130001872300
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22382320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] Involvement of microRNA in the induction of drug-metabolizing enzymes.2012
- Author(s)
  Shizu R, Numazawa S, Yoshida T.
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 132 Pages: 311-318
- NAID
  130001872026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] Possible involvement of transient receptor potential channels in electrophile-induced insulin secretion from RINm5F cells2012
- Author(s)
  Numazawa S, Takase M, Ahiko T, Ishii M, Shimizu S, Yoshida T
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 35(3) Pages: 346-354
- NAID
  130001872315
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22382320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] 6-Mercaptopurine-induced histopathological changes and xanthine oxidase expression in rat placenta2012
- Author(s)
  Taki K, Fukushima T, Ise R, Horii I, Yoshida T
- Journal Title
  
  J Toxicol Sci
  
  Volume: 37(3) Pages: 607-615
- NAID
  10030436433
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22688000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] Involvement of interleukin-1 in lead nitrate-induced hypercholesterolemia in mice.2012
- Author(s)
  Kojima M, Ashino T, Yoshida T, Iwakura Y, Degawa M.
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 35 Pages: 246-250
- NAID
  130001872300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] Auranofin protects against cocaine-induced hepatic injury through induction of heme oxygenase-12011
- Author(s)
  Ashino T, Sugiuchi J, Uehara J, Naito-Yamamoto Y, Kenmotsu S, Iwakura Y, Shioda S, Numazawa S, Yoshida T
- Journal Title
  
  J Toxicol Sci
  
  Volume: 36(5) Pages: 635-643
- NAID
  10029481491
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22008538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] MicroRNAs expression in the ethylene glycol monomethyl ether-induced testicular lesion.2011
- Author(s)
  Fukushima T, Taki K, Ise R, Horii I, Yoshida T.
- Journal Title
  
  J Toxicol Sci
  
  Volume: 36 Pages: 601-611
- NAID
  10029481384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] Auranofin protects against cocaine-induced hepatic injury through induction of heme oxygenase-1.2011
- Author(s)
  Ashino T, Sugiuchi J, Uehara J, Naito-Yamamoto Y, Kenmotsu S, Iwakura Y, Shioda S, Numazawa S, Yoshida T.
- Journal Title
  
  J Toxicol Sci
  
  Volume: 36 Pages: 635-643
- NAID
  10029481491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] Interleukin-1 controls the constitutive expression of the Cyp7a1 gene by regulating the expression of Cyp7a1 transcriptional regulators in the mouse liver.2011
- Author(s)
  Kojima M, Ashino T, Yoshida T, Iwakura Y, Degawa M.
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 34 Pages: 1644-1647
- NAID
  130001086603
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] MicroRNAs expression in the ethylene glycol monomethyl ether-induced testicular lesion2011
- Author(s)
  Fukushima T, Taki K, Ise R, Horii I, Yoshida T
- Journal Title
  
  J Toxicol Sci
  
  Volume: 36(5) Pages: 601-611
- NAID
  10029481384
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22008535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] Comparison of in vitro metabolic conversion of capecitabine to 5-FU in rats, mice, monkeys and humans--toxicological implications2011
- Author(s)
  Shindoh H, Nakano K, Yoshida T, Ishigai M
- Journal Title
  
  J Toxicol Sci
  
  Volume: 36(4) Pages: 411-422
- NAID
  10029340169
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21804305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] Interleukin-1 controls the constitutive expression of the Cyp7a1 gene by regulating the expression of Cyp7a1 transcriptional regulators in the mouse liver2011
- Author(s)
  Kojima M, Ashino T, Yoshida T, Iwakura Y, Degawa M
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 34(10) Pages: 1644-1647
- NAID
  130001086603
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21963511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Journal Article] Comparison of in vitro metabolic conversion of capecitabine to 5-FU in rats, mice, monkeys and humans--toxicological implications.2011
- Author(s)
  Shindoh H, Nakano K, Yoshida T, Ishigai M.
- Journal Title
  
  J Toxicol Sci
  
  Volume: 36 Pages: 411-422
- NAID
  10029340169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] 血管内膜肥厚における酸化ストレス応答性転写因子Nrf2 の役割2012
- Author(s)
  小柴郁,芦野隆,山本雅之,吉田武美,沼澤聡
- Organizer
  第56回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] 血管平滑筋細胞遊走および血管リモデリングにおけるレドックス感受性転写因子Nrf2の役割2012
- Author(s)
  芦野隆,山本雅之,吉田武美,沼澤聡
- Organizer
  第39回日本毒性学会
- Place of Presentation
  仙台
- Year and Date
  2012-07-17
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] The redox-sensitive transcription factor Nrf2 regulates reactive oxygen species-dependent vascular smooth muscle cell migration and neointimal hyperplasia2012
- Author(s)
  Ashino T, Yamamoto M, Yoshida T, Numazawa S
- Organizer
  The 10th Korea-Japan Joint Symposium on Vascular Biology
- Place of Presentation
  徳島
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] オーラノフィンによるヘムオキシゲナーゼ-1誘導を介したコカイン誘発肝障害防御作用2012
- Author(s)
  芦野隆,上原淳奈,杉内仁子,岩倉洋一郎,塩田清二,沼澤聡,吉田武美
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] ＳＥＬＥＸ法による乱用薬物3,4-methylenedioxyamphetamine（ＭＤＡ）結合DNAアプタマーの作製2012
- Author(s)
  諏訪雅子，沼澤聡，吉田武美
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] Auranofin protects against cocaine-induced hepatic injury through induction of heme oxygenase-12012
- Author(s)
  Ashino T, Sugiuchi J, Uehara J, Naito-Yamamoto Y, Kenmotsu S, Iwakura Y, Shioda S, Numazawa S, Yoshida T
- Organizer
  Society of Toxicology 2012 Annual Meeting
- Place of Presentation
  サンフランシスコ(アメリカ合衆国)
- Year and Date
  2012-03-12
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] Preparation of ssDNA aptamers, selectively bind 3,4-methylenedioxyamphetamine (MDA), by SELEX method2012
- Author(s)
  Suwa M, Numazawa S, Yoshida T
- Organizer
  The 50th Annual Meeting of the International Association of Forensic Toxicologists
- Place of Presentation
  浜松
- Year and Date
  2012-06-03
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] Role of the redox-sensitive transcription factor Nrf2 in vascular smooth muscle cell migration and vascular remodeling2012
- Author(s)
  Ashino T, Yamamoto M, Yoshida T, Numazawa S
- Organizer
  The 6th International Congress of Asian Society of Toxicology
- Place of Presentation
  仙台
- Year and Date
  2012-07-20
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] SELEX法による乱用薬物3,4-methylenedioxyamphetamine(MDA)結合DNAアプタマーの作製2012
- Author(s)
  諏訪雅子,沼澤聡,吉田武美
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] Auranofin protects against cocaine-induced hepatic injury through induction of heme oxygenase-12012
- Author(s)
  Ashino T, Sugiuchi J, Uehara J, Naito-Yamamoto Y, Kenmotsu S, Iwakura Y, Shioda S, Numazawa S, Yoshida T.
- Organizer
  SOT 2012 Annual Meeting
- Place of Presentation
  サンフランシスコ
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] 炎症誘発によるパーキンソン病モデルマウスの作製とIL-1の重要性2012
- Author(s)
  田中佐知子,石井敦子,大滝博和,塩田清二,吉田武美,沼澤聡
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] ニコチン脳室内投与によるマウス海馬における神経毒性発現に関連するmiRNAの変動2011
- Author(s)
  瀧憲二,丸茂瑠佳,芦野隆,田中佐知子,沼澤聡,吉田武美
- Organizer
  38回日本トキシコロジー学会
- Place of Presentation
  横浜
- Year and Date
  2011-07-11
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] miRNA，mRNA変動に関連した6-Mercaptopurineのラット胎盤毒性2011
- Author(s)
  瀧憲二，福島民雄，伊勢良太，堀井郁夫，吉田武美
- Organizer
  第38回日本トキシコロジー学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] ニコチン脳室内投与によるマウス海馬における神経毒性発現に関連するmiRNAの変動2011
- Author(s)
  瀧憲二，丸茂瑠佳，芦野隆，田中佐知子，沼澤聡，吉田武美
- Organizer
  第38回日本トキシコロジー学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] 大腸菌内毒素リポポリサッカライドを用いたパーキンソン病モデル動物の作成と神経変性機序におけるIL-1βの役割2011
- Author(s)
  田中佐知子,石井敦子,大滝博和,塩田清二,沼澤聡,吉田武美
- Organizer
  第38回日本トキシコロジー学会
- Place of Presentation
  横浜
- Year and Date
  2011-07-12
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] miRNA,mRNA変動に関連した6-Mercaptopurineのラット胎盤毒性2011
- Author(s)
  瀧憲二,福島民雄,伊勢良太,堀井郁夫,吉田武美
- Organizer
  第38回日本トキシコロジー学会
- Place of Presentation
  横浜
- Year and Date
  2011-07-11
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] 血管内膜肥厚における酸化ストレス応答性転写因子Nrf2 の役割
- Author(s)
  小柴　郁、芦野　隆、山本雅之、吉田武美、沼澤　聡
- Organizer
  第５６回日本薬学会関東支部大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23659068
[Presentation] 血管平滑筋細胞遊走および血管リモデリングにおけるレドックス感受性転写因子Nrf2の役割
- Author(s)
  芦野　隆、山本雅之、吉田武美、沼澤　聡
- Organizer
  第３９回日本毒性学会学術年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23659068

1. TANAKA Sachiko (00197419)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. ASHINO Takashi (00338534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
3. 貝崎明日香 (70407443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 堀井郁夫 (10527203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 沼澤聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 山本雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yoshida Takemi 吉田 武美

YOSHIDA Takemi 吉田 武美

Research Projects

Research Products

Co-Researchers

Mutual regulation of physiological gases by xenobioticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

薬毒物の毒性発現におけるマイクロRNAの変動解析とその安全性評価への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Microarray analysis of 6-mercaptopurine-induced-toxicity-related genes and microRNAs in the rat placenta2013

Author(s)

Journal Title

NAID

URL

Data Source

[Journal Article] Cross-talk between constitutive androstane receptor and hypoxia-inducible factor in the regulation of gene expression.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Redox-Sensitive Transcription Factor Nrf2 Regulates Vascular Smooth Muscle Cell Migration and Neointimal Hyperplasia.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MicroRNA-122 down-regulation is involved in phenobarbital-mediated activation of the constitutive androstane receptor2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Involvement of microRNA in the induction of drug-metabolizing enzymes2012

Author(s)

Journal Title

NAID

URL

Data Source

[Journal Article] Possible involvement of transient receptor potential channels in electrophile-induced insulin secretion from RINm5F cells.2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Involvement of interleukin-1 in lead nitrate-induced hypercholesterolemia in mice2012

Author(s)

Journal Title

NAID

URL

Data Source

[Journal Article] Involvement of microRNA in the induction of drug-metabolizing enzymes.2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Possible involvement of transient receptor potential channels in electrophile-induced insulin secretion from RINm5F cells2012

Author(s)

Journal Title

NAID

URL

Data Source

[Journal Article] 6-Mercaptopurine-induced histopathological changes and xanthine oxidase expression in rat placenta2012

Author(s)

Journal Title

NAID

URL

Data Source

[Journal Article] Involvement of interleukin-1 in lead nitrate-induced hypercholesterolemia in mice.2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Auranofin protects against cocaine-induced hepatic injury through induction of heme oxygenase-12011

Author(s)

Journal Title

Yoshida Takemi 吉田武美

YOSHIDA Takemi 吉田武美