YOKOZAWA Takako 横澤隆子

Researcher Number	90019133
External Links
Affiliation (based on the past Project Information) *help	2007 – 2008: University of Toyama, 和漢医薬学総合研究所, 准教授 1998 – 2000: 富山医科薬科大学, 和漢薬研究所, 助教授 1991 – 1995: Toyama Medical and Pharmaceutical University, Research Institute for Wakan-Yaku, Associate Professor, 和漢薬研究所, 助教授 1990: 富山医科薬科大学, 和漢薬研究所, 助手
Review Section/Research Field	Principal Investigator 医学一般 / Eating habits, studies on eating habits / 内科学一般 / Public health/Health science
Keywords	Principal Investigator Methylguanidine / Creatol / Creatinine / Prostaglandin E_2 / Kallikrein / Kinin / Magnesium lithospermate B / Methylguanidine synthase / 柿 / ポリフェノール … More / オリゴマー / 加齢 / 寿命 / 記憶 / VEGFR-2 / 機能性食品 / Lithospermic acid B Mg 塩 / 腎機能 / kinin / Lithospermic acid B Mg塩 / kallikrein / 血圧 / Lithospermic and B Mg塩 / Prostaglandin / Renal function / Blood pressure / L-Gulono-γ-lactone oxidase / L-gulono-γ-lactone oxidase / Cratol / Lーgulonoーrーlactone oxidase / フラビン酵素 / L-Gulono-gammma-lactone oxidase / 緑茶 / タンニン / creatinine / creatol / methylguanidine / (‐)‐epigallocatechim3‐O‐gallate / Green tea / Tannin / 羅布麻 / 酸化LDL / 粥状動脈硬化 / 内皮細胞 / マクロファージ / 抗酸化物 / SAM / グルタチオン / ハイペロシド / イソケルシトリン / クロロゲン酸 / コレステロールエステル / 動脈硬化 / Luobuma / oxidized LDL / atherosclerosis / endothelial cell / macrophage / antioxidant Less

Research Projects
(5 results)
Research Products
(25 results)

Preparation of Oligomeric Proanthocyanidin from Persimmon and Its Anti-Aging CharacterizationPrincipal Investigator
- Principal Investigator
  
  YOKOZAWA Takako
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  University of Toyama
Evaluation of Luobuma as an AntioxidantPrincipal Investigator
- Principal Investigator
  
  YOKOZAWA Takako
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Public health/Health science
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
Influence of Green Tea Tannin in Creatinine-Oxidizing SystemPrincipal Investigator
- Principal Investigator
  
  YOKOZAWA Takako
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
Mechanism of Methylguanidine Formation from CreatolPrincipal Investigator
- Principal Investigator
  
  YOKOZAWA Takako
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  医学一般
- Research Institution
  Toyama Medical and Pharmaceutical University
Effect of Magnesium Lithospermate B on Renal Circulatory StatePrincipal Investigator
- Principal Investigator
  
  YOKOZAWA Takako
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  医学一般
- Research Institution
  Toyama Medical and Pharmaceutical University

All 2008 2007 Other

All Journal Article Presentation Book Patent

[Book] 腎とフリーラジカルー第9集2008
- Author(s)
  Lee Y. A, Cho E. J., Yokozawa T.
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-19500661
[Book] 腎とフリーラジカル-第9集2008
- Author(s)
  Lee Y.A, Cho E.J., Yokozawa T.
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-19500661
[Journal Article] Effects of Proanthocyanidin Preparations on Hyperlipidemia and Other Biomarkers in Mouse Model of Type 2 Diabetes2008
- Author(s)
  Lee Y. A, Cho E. J., Yokozawa T.
- Journal Title
  
  J. Agric. Food Chem. 56
  
  Pages: 7781-7789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500661
[Journal Article] Protective Effect of Persimmon (Diospyros Kaki) Peel Proanthocyanidin against Oxidative Damage under H_2O_2-Induced Cellular Senescence2008
- Author(s)
  Lee Y.A, Cho E.J., Yokozawa T
- Journal Title
  
  Biol. Pharm. Bull 31
  
  Pages: 1265-1269
- NAID
  110006684352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500661
[Journal Article] Effects of Proanthocyanidin Preparations on Hyperlipidemia and Other Biomarkers in Mouse Model of Type 2 Diabetes2008
- Author(s)
  Lee Y.A, Cho E.J., Yokozawa T.
- Journal Title
  
  J. Agric. Food Chem 56
  
  Pages: 7781-7789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500661
[Journal Article] Protective Effect of Persimmon (Diospyros Kaki) Peel Proanthocyanidin against Oxidative Damage under H_2O_2-Induced Cellular Senescence2008
- Author(s)
  Lee Y. A, Cho E. J., Yokozawa T.
- Journal Title
  
  Biol. Pharm. Bull. 31
  
  Pages: 1265-1269
- NAID
  110006684352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500661
[Journal Article] Preparation, Characterization, and Antioxidative Effects of Oligomeric Proanthocyanidin-L-Cysteine Complexes2007
- Author(s)
  Fujii H., Nakagawa T., Nishioka H., Sato E., Hirose A., Ueno Y., Sun B., Yokozawa T., Nonaka G.
- Journal Title
  
  J. Agric. Food Chem 55
  
  Pages: 1525-1531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500661
[Journal Article] Ameliorative Effects of Proanthocyanidin on Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats2007
- Author(s)
  Lee Y.A, Kim Y.J., Cho E.J., Yokozawa T
- Journal Title
  
  J. Agric. Food Chem 55
  
  Pages: 9395-9400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500661
[Journal Article] Protective effect of persimmon peel polyphenol against high glucose- induced oxidative stress in LLC-PK_1 cells2007
- Author(s)
  Yokozawa T., Kim Y.A., Kim H.Y., Lee Y.A, Nonaka G
- Journal Title
  
  Food Chem. Toxicol 45
  
  Pages: 1979-1987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500661
[Journal Article] Amehorative Effects of Proanthocyanidin on Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats2007
- Author(s)
  Lee Y.A, Kim Y.J., Cho E.J., Yokozawa T.
- Journal Title
  
  J. Agric. Food Chem 55
  
  Pages: 9395-9400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500661
[Journal Article] Protective effect of persimmon peel polyphenol against high glucose induced oxidative stress in LLC-PK_1cells2007
- Author(s)
  Yokozawa T., Kim Y.A., Kim H.Y. Lee Y.A. Nonaka G.
- Journal Title
  
  Food Chem. Toxicol 45
  
  Pages: 1979-1987
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500661
[Journal Article] Preparation, Characterization, and Antioxidative Effects of Oligomeric Proanthocyanidin-L-Cysteine Complexes2007
- Author(s)
  Fujii H., Nakagawa T., Nishioka H., Sato E., Hirose A., Ueno Y., Sun B., Yokozawa T., Nonaka G
- Journal Title
  
  J. Agric. Food Chem 55
  
  Pages: 1525-1531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500661
[Journal Article] Inhibitory Activities of Proanthocyanidins from Persimmon against Oxidative Stress and Digestive Enzymes Related to Diabetes2007
- Author(s)
  Lee Y.A, Cho E.J., Tanaka T., Yokozawa T.
- Journal Title
  
  J. Nutr. Sci. Vitaminol 53
  
  Pages: 287-292
- NAID
  110006317290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500661
[Journal Article] Inhibitory Activities of Proanthocyanidines from Persimmon against Oxidative Stress and Digestive Enzymes Related to Diabetes2007
- Author(s)
  Lee Y.A, Cho E.J., Tanaka T., Yokozawa T
- Journal Title
  
  J. Nutr. Sci. Vitaminol 55
  
  Pages: 287-292
- NAID
  110006317290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500661
[Journal Article] Modulation of Oxidative Stress and Melanogenesis by Proanthocyanidins
- Author(s)
  Kim Y.J., Yokozawa T
- Journal Title
  
  Biol. Pharm. Bull (in press)
- NAID
  130000117209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500661
[Patent] 柿ポリフェノールオリゴマー2007
- Inventor(s)
  横澤隆子, 田中隆, 太田富久, 奥村文男, 布沢哲二
- Industrial Property Rights Holder
  明治薬品株式会社
- Industrial Property Number
  2007-165247
- Filing Date
  2007-06-22
- Data Source
  KAKENHI-PROJECT-19500661
[Patent] 柿ポリフェノールオリゴマー2007
- Inventor(s)
  横澤隆子, 田中隆, 太田富久, 奥村文男, 布沢哲二
- Industrial Property Rights Holder
  明治薬品株式会社
- Industrial Property Number
  2007-165247
- Filing Date
  2007-06-22
- Data Source
  KAKENHI-PROJECT-19500661
[Presentation] 柿果実のプロアントシアニジンオリゴマーによる抗老化作用2008
- Author(s)
  李英娥, 横澤隆子
- Organizer
  第20回腎とフリーラジカル研究会
- Place of Presentation
  大阪
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-19500661
[Presentation] Anti-Aging Effects of Oligomeric Proanthocyanidin Isolated from Persimmon Fruits2008
- Author(s)
  Lee Y.A, Cho E.J., Yokozawa T
- Organizer
  The 12th International Conference on Oriental Medicine of Dong-Eui & Daegu Haany University
- Place of Presentation
  Busan, Korea
- Year and Date
  2008-08-21
- Data Source
  KAKENHI-PROJECT-19500661
[Presentation] Improved Effects and Its Mechanism of Oligomeric Proanthocyanidins Isolated from Persimmon against Memory Impairment2008
- Author(s)
  Lee Y.A, Cho E.J., Yokozawa T.
- Organizer
  2008 International Symposium and Annual Meeting "Chronic Disease and LOHAS Foods"
- Place of Presentation
  Jeju Island, Korea
- Data Source
  KAKENHI-PROJECT-19500661
[Presentation] Improved Effects and Its Mechanism of Oligomeric Proanthocyanidins Isolated from Persimmon against Memory Impairment2008
- Author(s)
  Lee Y. A, Cho E. J., Yokozawa T.
- Organizer
  2008 International Symposium and Annual Meeting “Chronic Disease and LOHAS Foods"
- Place of Presentation
  Jeju Island, Korea
- Data Source
  KAKENHI-PROJECT-19500661
[Presentation] 老化促進モデルマウスの記憶障害に対する柿ポリフェノールオリゴマーの影響2008
- Author(s)
  李英娥, 趙恩珠, 田中隆, 東田千尋, 横澤隆子
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19500661
[Presentation] 柿ポリフェノールの2型糖尿病モデルによる検討2008
- Author(s)
  李英娥, 趙恩珠, 田中隆, 横澤隆子
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19500661
[Presentation] Protective Effects of Proanthocyanidin from Persimmon Peel on Oxidative Stress and Inflammation in Diabetic Rats2007
- Author(s)
  Lee Y.A, Cho E.J., Yokozawa T.
- Organizer
  The Korean Nutrition Society International Conference in Commemoration of the 40th Anniversary
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-19500661
[Presentation] Protective Eflbcts of Proanthocyanidin from Persimmon Peel on Oxidative Stress and Inflammation in Diabetic Rats2007
- Author(s)
  Lee Y.A, Cho E.J., Yokozawa T.
- Organizer
  The Korean Nutrition Society International Conference in Commemoration of the 40th Anniversary
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-19500661

YOKOZAWA Takako 横澤 隆子

Research Projects

Research Products

Preparation of Oligomeric Proanthocyanidin from Persimmon and Its Anti-Aging CharacterizationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of Luobuma as an AntioxidantPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Influence of Green Tea Tannin in Creatinine-Oxidizing SystemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of Methylguanidine Formation from CreatolPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of Magnesium Lithospermate B on Renal Circulatory StatePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 腎とフリーラジカルー第9集2008

Author(s)

Publisher

Data Source

[Book] 腎とフリーラジカル-第9集2008

Author(s)

Publisher

Data Source

[Journal Article] Effects of Proanthocyanidin Preparations on Hyperlipidemia and Other Biomarkers in Mouse Model of Type 2 Diabetes2008

Author(s)

Journal Title

Data Source

[Journal Article] Protective Effect of Persimmon (Diospyros Kaki) Peel Proanthocyanidin against Oxidative Damage under H_2O_2-Induced Cellular Senescence2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Effects of Proanthocyanidin Preparations on Hyperlipidemia and Other Biomarkers in Mouse Model of Type 2 Diabetes2008

Author(s)

Journal Title

Data Source

[Journal Article] Protective Effect of Persimmon (Diospyros Kaki) Peel Proanthocyanidin against Oxidative Damage under H_2O_2-Induced Cellular Senescence2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Preparation, Characterization, and Antioxidative Effects of Oligomeric Proanthocyanidin-L-Cysteine Complexes2007

Author(s)

Journal Title

Data Source

[Journal Article] Ameliorative Effects of Proanthocyanidin on Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats2007

Author(s)

Journal Title

Data Source

[Journal Article] Protective effect of persimmon peel polyphenol against high glucose- induced oxidative stress in LLC-PK_1 cells2007

Author(s)

Journal Title

Data Source

[Journal Article] Amehorative Effects of Proanthocyanidin on Oxidative Stress and Inflammation in Streptozotocin-Induced Diabetic Rats2007

Author(s)

Journal Title

Data Source

[Journal Article] Protective effect of persimmon peel polyphenol against high glucose induced oxidative stress in LLC-PK_1cells2007

Author(s)

Journal Title

Data Source

[Journal Article] Preparation, Characterization, and Antioxidative Effects of Oligomeric Proanthocyanidin-L-Cysteine Complexes2007

YOKOZAWA Takako 横澤隆子