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YAMASHITA Junkoh  山下 純宏

ORCIDConnect your ORCID iD *help
Researcher Number 90026948
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2003 – 2004: 金沢大学, 医学系研究科, 教授
2001 – 2002: 金沢大学, 大学院・医学系研究科, 教授
2001: 金沢大学, 医学系研究科, 教授
1993 – 2000: 金沢大学, 医学部, 教授
1988 – 1990: 金沢大学, 医学部, 教授
1986 – 1987: 京都大学, 医学部, 助教授
1986: 京都大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Cerebral neurosurgery / Cerebral neurosurgery
Except Principal Investigator
Cerebral neurosurgery
Keywords
Principal Investigator
glioma / MMP / 神経膠芽腫 / retrovirus vector / 浸潤 / testican / triple stranded DNA / anti-gene strategy / invasion / aggrecanase … More / 脳腫瘍 / EGFR / retrovirusvector / chemokine / adenovirus vector / MCAF / MIP-1alpha / Caspase-3 / ets-1 / integrin / glioblastoma / glioma invasion / matrix metalloproteinase / extracellular matrix / Testican / Apaf-1 / TP53 / ADAMTS / proteoglycan / 樹状細胞 / 免疫治療 / 細胞障害性Tリンパ球 / 頚部リンパ節 / 悪性神経膠芽腫瘍 / 腫瘍特異抗原 / visual function / MEG / dominant hemisphere / not invasive study / ocular dominance / visual evoked magnetic field / dipole moment / age / latency / 三重鎖DNA, / アンチジーン / 上皮成長因子受容体 / 癌遺伝子 / グリオーマ / 扁平上皮癌 / レトロウイルスベクター / 遺伝子療法 / 三重鎖DNA / Sp-1 / DNA triplex, antigene, EGFR,Sp-1, human glioma, human squamous cell carcinoma, retrovirus vector, gene therapy / triplestrandedDNA / anti-genestrategy / SP-1 / c-erb B gene / MIP-1 alpha / specificity / chimera / env / EGF / 悪性神経膠腫 / apoptosis / カスパーゼ3 / Fas / アポトーシス / CPP32 / PARP / apoptosis, / 髄腔内播種 / 転写因子 / 神経膠芽種 / TIMP / dissemination / 細胞外マトリックス / 湿潤 / ECM / Crk I / AT / RT / hSNF5 / INI1 / cyclin D1 / γ-catenin / ADAMTS-5 / brevican / microcatheter fence-post / LOH 1p,19q / deep-Seated gliobiastoma / TP53 mutation / Ets-1 / microarray / peripheral nerve tumor / 12q22-23 LOH / Ets transcription factor / Crk 1 / 遺伝子操作 / IFN-γ遺伝子 / マウス神経系腫瘍 / 腫瘍免疫 / 養子免疫 / IFNーγ遺伝子 / マウス神経芽細胞腫 / MHC classI / 養子免疫療法 / Interferon gamma / Gene transfer / Retroviral vector / Gytotoxic T lymphocytes / Major histocompatibility complex / Immunotherapy / Brain neoplasms … More
Except Principal Investigator
カドヘリン / 髄膜腫 / クモ膜絨毛 / ウエスタンブロッティング / 免疫組織化学 / アドリアマイシン / シスプラチン / オキシセルロース / ポリ乳酸 / 徐放性抗癌剤 / 脳腫瘍 / キラーT細胞 / 腫瘍抗原 / グリオーマ / IL2 Less
  • Research Projects

    (14 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (21 People)
  •  脳誘発磁界測定による視野認知機能の新規評価法の開発Principal Investigator

    • Principal Investigator
      賀戸 久, 山下 純宏
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kanazawa Institute of Technology
      Kanazawa University
  •  Analysis of transcription factors and of crosstalk between proteinase and extracellular matrix that are related to invasive process of glioblastomaPrincipal Investigator

    • Principal Investigator
      WATANABE Takuya, 山下 純宏
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Department of Neurosurgery, Graduate School of Medical Science, Kanazawa University, Kanazawa
  •  悪性神経膠腫由来の浸潤細胞障害性T細胞が認識する脳腫瘍特異的抗原ペプチドの同定Principal Investigator

    • Principal Investigator
      山下 純宏
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kanazawa University
  •  The analysis of transcription factor and ECM degradation enzyme associated with invasion of glioblastomaPrincipal Investigator

    • Principal Investigator
      YAMASHITA Junkoh
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kanazawa University
  •  脳に特異的なマトリックスメタロプロテアーゼ遺伝子の単離Principal Investigator

    • Principal Investigator
      山下 純宏
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kanazawa University
  •  The analysis of invasion associated gene in glioblastomaPrincipal Investigator

    • Principal Investigator
      YAMASHITA Junkoh
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kanazawa University
  •  Analysis of cell death inducing gene in human malignant gliomasPrincipal Investigator

    • Principal Investigator
      YAMASHITA Junkoh
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kanazawa University
  •  Inhibition of Gene Expression from the Human c-erb B Gene Promoter by a Retroviral Vector Expressing Anti-gene RNAPrincipal Investigator

    • Principal Investigator
      YAMASHITA Junkoh
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KANAZAWA UNIVERSITY
  •  Development of chemokine-expressing retrovirus vector system in malignant gliomasPrincipal Investigator

    • Principal Investigator
      YAMASHITA Junkoh
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      KANAZAWA UNIVERSITY
  •  INHIBITION OF TRANSCRIPTION OF THE HUMAN EGFR GENE IN GLIOMA BY SITE-SPECIFIC OLIGONUCLEOTIDES DESIGNED TO FORM DNA TRIPLE HELICESPrincipal Investigator

    • Principal Investigator
      YAMASHITA Junkoh
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kanazawa University
  •  脳腫瘍における細胞間接着因子(カドヘリン)の研究

    • Principal Investigator
      山嶋 哲盛
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kanazawa University
  •  Adoptive Immunotherapy for Malignant Brain Tumors Using Killer T Lymphocytes Enhanced by Interferon Gamma Gene TransferPrincipal Investigator

    • Principal Investigator
      YAMASHITA Junkoh
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kanazawa University
      Kyoto University
  •  悪性脳腫瘍の手術時における留置用徐放性抗癌剤の開発

    • Principal Investigator
      堀 了平
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  ヒト腫瘍細胞特異的キラーT細胞の誘導とその応用

    • Principal Investigator
      難波 雄二郎
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University

All 2005 2004 2003

All Journal Article Book

  • [Book] Brain Tumor Surgery-new strategy based on biological behavior of brain tumors-2005

    • Author(s)
      Yamashita J (Editor)
    • Publisher
      Published by Medica shuppan [Osaka, Japan]
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Book] 脳腫瘍の外科-Biological behaviorにのっとった新しい治療戦略-2005

    • Author(s)
      山下純宏(編)
    • Total Pages
      338
    • Publisher
      メディカ出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Cyclin D1 is overexpressed in atypical teratoid/rhabdoid tumor with hSNF5/INI1 genes inactivation.2005

    • Author(s)
      Fujisawa H, Misaki K, Takabatake Y, Hasegawa M, Yamashita J
    • Journal Title

      J Neurooncol 73

      Pages: 117-124

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Therapeutic strategy of oligodendroglioma based on LOH 1p and 19q.2005

    • Author(s)
      Fujisawa H, Miyashita K, Tachibana O, Hasegawa M, Yamashita J
    • Journal Title

      Brain Tumor Surgery[Japanese]

      Pages: 142-149

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Human glioblastomas overexpress ADAMTS-5 that degrades brevican2005

    • Author(s)
      Nakada M, Miyamori H, Kita D, Takahashi T, Yamashita J, Sato H, Miura R, Yamaguchi Y, Okada Y
    • Journal Title

      Acta Neuropathol (Berl) 110

      Pages: 239-246

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Correlation of gamma-catenin expression with good prognosis in medulloblastomas.2005

    • Author(s)
      Misaki K, Marukawa K, Hayashi Y, Fukusato T, Minamoto T, Hasegawa M, Yamashita J, Fujisawa H
    • Journal Title

      J Neurosurg 102

      Pages: 197-206

    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Cyclin D1 is overexpressed in atypical teratoid/rhabdoid tumor with hSNF5/INI1 gene inactivation.2005

    • Author(s)
      Fujisawa H, Misaki K, Takabatake Y, Hasegawa M, Yamashita J
    • Journal Title

      J Neurooncol 73

      Pages: 117-124

    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Correlation of gamma-catenin expression with good prognosis in medulloblastomas.2005

    • Author(s)
      Misaki K, Marukawa K, Hayashi Y, Fukusato T, Minamoto T, Hasegawa M,. Yamashita J, Fujisawa H
    • Journal Title

      J Neurosurg 102

      Pages: 197-206

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Catheter guided brain tumor surgery (fence-post catheter technique) using navigation system, especially on supratentorial intra-axial tumors.2005

    • Author(s)
      Kita D.Hasegawa M, Yamashita J
    • Journal Title

      Brain Tumor Surgery[Japanese]

      Pages: 307-313

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] テント上脳実質内腫瘍手術におけるnavigation system下fence-post catheter法の有用性2005

    • Author(s)
      喜多大輔, 長谷川光広, 山下純宏
    • Journal Title

      脳腫瘍の外科-Biological beheviorにのっとった新しい治療戦略-

      Pages: 307-313

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] テント上脳実質内腫瘍手術におけるnavigation system下fence-post catheter法の有用性2005

    • Author(s)
      喜多大輔, 長谷川光広, 山下純宏
    • Journal Title

      脳腫瘍の外科-Biological behaviorにのっとった新しい治療戦略-

      Pages: 307-313

    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] LOH 1p,19qに基づいたoligodendroglial tumorの治療戦略2005

    • Author(s)
      藤沢弘範, 宮下勝吉, 立花修, 長谷川光広, 山下純宏
    • Journal Title

      脳腫瘍の外科-Biological behaviorにのっとった新しい治療戦略-

      Pages: 142-149

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Human glioblastomas overexpress ADAMTS-5 that degrades brevican.2005

    • Author(s)
      Nakada M, Miyamori H, Kita D, Takahashi T, Yamashita J, Sato H, Miura R, Yamaguchi Y, Okada Y
    • Journal Title

      Acta Neuropathol (Berl) 110

      Pages: 239-246

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Correlation of gamma-catenin expression with good prognosis in medulloblastomas2005

    • Author(s)
      Misaki K, Marukawa K, Hayashi Y, Fukusato T, Minamoto T, Hasegawa M, Yamashita J, Fujisawa H
    • Journal Title

      J Neurosurg 102

      Pages: 197-206

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Cyclin D1 is overexpressed in atypical teratoid/rhabdoid tumor with hSNF5/INI1 gene inactivation2005

    • Author(s)
      Fujisawa H, Misaki K, Takabatake Y, Hasegawa M, Yamashita J
    • Journal Title

      J Neurooncol 73

      Pages: 117-124

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Surgical pathology of spinal schwannoma : has the nerve of its origin been preserved or already degenerated during tumor growth?2005

    • Author(s)
      Hasegawa M, Fujisawa H, Hayashi Y, Tachibana O, Kida S, Yamashita J
    • Journal Title

      Clin Neuropathol 24

      Pages: 19-25

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Molecular genetic analysis of deep-seated glioblastomas2004

    • Author(s)
      Hayashi Y, Yamashita J, Watanabe T
    • Journal Title

      Cancer Genet Cytogenet 153

      Pages: 64-68

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Autologous amnion graft for repair of myelomeningocele : technical note and clinical implication.2004

    • Author(s)
      Hasegawa M, Fujisawa H, Hayashi Y, Yamashita J
    • Journal Title

      J Clin Neurosci 11

      Pages: 408-411

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Autologous amnion graft for repair of myelomeningocele : technical note and clinical implication2004

    • Author(s)
      Hasegawa M, Fujisawa H, Hayashi Y, Yamashita J
    • Journal Title

      J Clin Neurosci 11

      Pages: 408-411

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Molecular analysis of the rhabdoid predisposition syndrome in a child : a novel germline hSNF5/INI1 mutation and absence of c-myc amplification2003

    • Author(s)
      Fujisawa, H., Takabatake, Y., Fukusato, T., Tachibana, O., Tsuchiya, Y., Yamashita, J
    • Journal Title

      J Neurooncol 63

      Pages: 257-262

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Testican 2 abrogates inhibition of membrane-type matrix metalloproteinases by other testican family proteins.2003

    • Author(s)
      Nakada M, Miyamori H, Yamashita J, Sato H
    • Journal Title

      Cancer Res 63

      Pages: 3364-3369

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] The role of matrix metalloproteinases in glioma invasion2003

    • Author(s)
      Nakada M, Okada Y, Yamashita J.
    • Journal Title

      Front Biosci 8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Oxidized galectin-1 stimulates the migration of Schwann cells from both proximal and distal stumps of transected nerves and promotes axonal regeneration after peripheral nerve injury2003

    • Author(s)
      Fukaya K, Hasegawa M, Mashitani T, Kadoya T, Horie H, Hayashi Y, Fujisawa H, Tachibana O, Kida S, Yamashita J
    • Journal Title

      J Neuropathol Exp Neurol 62

      Pages: 162-172

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] CrkI adapter protein modulates cell migration and invasion in glioblastoma.2003

    • Author(s)
      Takino T, Nakada M, Miyamori H, Yamashita J, Yamada KM, Sato H
    • Journal Title

      Cancer Res 63

      Pages: 2335-2337

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Oxidized galectin-1 stimulates the migration of Schwann cells from both proximal and distal stumps of transected nerves and promotes axonal regeneration after peripheral nerve injury.2003

    • Author(s)
      Fukaya K, Hasegawa M, Mashitani T, Kadoya T, Horie H, Hayashi Y, Fujisawa H, Tachibana O, Kida, S, Yamashita J
    • Journal Title

      J Neuropathol Exp Neurol 62

      Pages: 162-172

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • [Journal Article] Frequent LOH at chromosome 12q22-23 and Apaf-1 inactivation in glioblastoma.2003

    • Author(s)
      Watanabe T, Hirota Y, Arakawa Y, Fujisawa H, Tachibana O, Hasegawa M, Yamashita J, Hayashi Y
    • Journal Title

      Brain Pathol 13

      Pages: 431-439

    • NAID

      110000140479

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390431
  • 1.  YAMAGUCHI Kazuo (00019879)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  TACHIBANA Osamu (40211362)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  WATANABE Takuya (90399775)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 4.  賀戸 久 (60278091)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  NAKADA Mitsutoshi (20334774)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  YAMASAKI Toshiki (50201835)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  山嶋 哲盛 (60135077)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  中条 達也 (00303298)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  中尾 眞二 (70217660)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  岡本 禎一 (40324074)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  藤沢 弘範 (40283113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  長谷川 光広 (70218460)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  堀 了平 (40001036)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  岩川 精吾 (50168548)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  乾 賢一 (70034030)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  奥村 勝彦 (60025707)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  難波 雄二郎 (50027322)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  花岡 正男 (30027304)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  喜多 大輔 (10377385)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 20.  徳力 康彦 (90155523)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  AMANUMA Hiroshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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