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KURODA Yoshihiro  黒田 義弘

ORCIDConnect your ORCID iD *help
Researcher Number 90093236
Other IDs
Affiliation (based on the past Project Information) *help 2016: 姫路獨協大学, 薬学部, 特別教授
2010 – 2015: 姫路獨協大学, 薬学部, 教授
2007: Himeji Dokkyo University, Faculty of Pharmaceutical Sciences, Professor
2006: 京都大学, 薬学研究科, 助教授
1997 – 2004: 京都大学, 薬学研究科, 助教授 … More
1999: 京都大学, 大学院・薬学研究科, 助教授
1987 – 1988: 京都大学, 薬学部, 助手
1986: 京大, 薬学部, 助手 Less
Review Section/Research Field
Principal Investigator
Physical pharmacy / Physical pharmacy / Biological pharmacy
Except Principal Investigator
Physical pharmacy / Periodontal dentistry / Periodontology
Keywords
Principal Investigator
EGFR / オリゴペプチド / oligopeptide / 局所麻酔薬 / ジブカイン / CDスペクトル / KIFMK / KIYEK / NYQQN / EGFR, IGF1R, 阻害ペプチド … More / 細胞膜透過性 / チロシンキナーゼ / IGF1R / 阻害ペプチド / ATP非競合的作用機序 / 細胞増殖 / 細胞毒性 / カスパーゼ3活性 / ナトリウムチャンネル / 不活性化ゲート / ペプチド / 相互作用 / NMRスペクトル / ミセル / フォスファチジルセリン / リポソーム / Sodium channel / Inactivation gate / Peptide / Local anesthetics / Dibucaine / Interaction / NMR spectrum / CD spectrum / アルツハイマー病 / プリオン病 / パーキンソン病 / αヘリックス / βシート / アミロイド線維 / Altzheimer disease / Prion disease / Parkinson's disease / α helix / β sheet / amyloid / CD spectra / 局所麻酔剤 / リドカイン / インスリン受容体 / リン酸化抑制 / 脱リン酸化 / local anesthetics / lidocaine / insulin receptor / suppression of phosphorylation / dephosphorylation / 上皮増殖因子受容体 / 自己リン酸化 / ATP非競合阻害剤 / ドッキングシミュレーション / 疑似基質 / 阻害剤 / 擬似基質 / epidermal growth factor receptor / autophosphorylation / ATP-non・competitive inhibitor / docking simulation / psuedosubstrate / テトラカイン / 二次元NMR / 核オーバーハウザー効果 / リン脂質 / ベシクル / ウィンドウ関数 / サインベル関数 / フォスファチジルコリン / 膜の運動性 / 関数処理 / Two-dimensional NMR / Window Function / Nuclear Overhauser Effect / Lipid Bilayer Vesicles / Spin Diffusion / Local Anesthetic / Tetracaine … More
Except Principal Investigator
歯肉上皮細胞 / 歯周病 / apo A-1 / EGFR / 歯肉線維芽細胞 / CCL17 / CCL22 / BAFF / APRIL / IL-22 / 細胞内侵入細菌 / IL-22 / P.gingivalis / 歯周病細菌 / 抗菌ペプチド / 糖タンパク質糖鎖 / 薬物・タンパク結合解析 / 糖鎖ミクロ不均一性 / 高速先端分析法 / 電子スプレー型飛行時間質量分析 / Naチャンネル蛋白 / プリオン蛋白 / glycochain / plasma protein binding / microheterogeneity / high-performance frontal analysis / ESI-T0F-MS / sodium channel inactivation gate peptide / prion protein / capillary electrophoresis / 表面プラズモン共鳴 / 生体超分子集合体 / 高次微細構造 / 高性能先端分析法 / 低密度リポタンパク質 / アミロイド / モンテカルロ計算 / 表面ブラズモン共鳴 / apoA-1 / 表面プラスモン共鳴 / 低密度血漿リポタンパク質 / 脂質2分子層 / 血漿アポリポタンパク質 / レセプター / アルツハイマー / シミュレーション / SPR / Biosuper molecular Assembly / Highly fine structure / high performance fromtall Analysis / low density lipo-protein / any loid / Monte Carlo-cal Less
  • Research Projects

    (10 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (14 People)
  •  Effect of IL-22 on immune response against periodontal bacteria

    • Principal Investigator
      Kato-kogoe Nahoko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Osaka Medical College
      Hyogo College of Medicine
  •  The effect of EGF receptor pathway on cytokine production in gingival fibroblasts

    • Principal Investigator
      KOGOE Nahoko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Himeji Dokkyo University
  •  The inhibitory potency of peptides derived from autophosphorylation sites of receptor tyrosine kinase in a non-ATP-competitive mechanism on tumor cells.Principal Investigator

    • Principal Investigator
      KURODA Yoshihiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Himeji Dokkyo University
  •  Studies on inhibitors for epidermal growth factor receptor based on oligopeptides which imitated pseudosubstratesPrincipal Investigator

    • Principal Investigator
      KURODA Yoshihiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Himeji Dokkyo University
      Kyoto University
  •  Mechanisms of suppression of insulin signaling by Na channel blockersPrincipal Investigator

    • Principal Investigator
      KURODA Yoshihiro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      KYOTO UNIVERSITY
  •  Structural investigations for developing the rapeutics of Altzheimer, prion, and Parkinson's diseasePrincipal Investigator

    • Principal Investigator
      KURODA Yoshihiro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      KYOTO UNIVERSITY
  •  医薬品化学領域における生体超分子集合体の高次微細構造と機能に関する研究

    • Principal Investigator
      TAGA Tooru
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      KYOTO UNIVERSITY
  •  Development of fine micro analytical method of drug recognition function of sugar chains

    • Principal Investigator
      NAKAGAWA Terumichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Physical pharmacy
    • Research Institution
      KYOTO UNIVERSITY
  •  Structural investiga tions for developing therapeutics of functional disorders due to the sodium channelPrincipal Investigator

    • Principal Investigator
      KURODA Yoshihiro
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      KYOTO UNIVERSITY
  •  Two-dimensional nuclear magnetic resonance spectroscopic studies on the interactions between membranes and drugsPrincipal Investigator

    • Principal Investigator
      KURODA Yoshihiro
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Kyoto University

All 2015 2013 2012 2011 Other

All Journal Article Presentation

  • [Journal Article] Suppressive effect of membrane-permeable peptides derived from autophosphorylation sites of the IGF-1 receptor on breast cancer cells.2015

    • Author(s)
      Kuroda Y, Kato-Kogoe N, Tasaki E, Yuasa-Sunagawa M, Yamanegi K, Nakasyo K, Nakase I, Futaki S, Tohyama Y, Hirose M
    • Journal Title

      Eur J Pharmacol.

      Volume: 765 Pages: 24-33

    • DOI

      10.1016/j.ejphar.2015.08.004

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460405, KAKENHI-PROJECT-26463151
  • [Journal Article] Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells.2013

    • Author(s)
      Kuroda Y, Kato-Kogoe N, Tasaki E, Murata E, Ueda K, Abe M, Miyamoto K, Nakase I, Futaki S, Tohyama Y, Hirose M.
    • Journal Title

      Eur J Pharmacol.

      Volume: 5 Pages: 87-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590076
  • [Journal Article] Oligopeptides derived from autophosphorylation sites of EGF receptor suppress EGF-stimulated responses in human lung carcinoma A549 cells2013

    • Author(s)
      Kuroda Y, Kato-Kogoe N, Tasaki E, Murata M, Ueda K, Abe M, Miyamoto K, Nakase I, Futaki S, Tohyama Y, Hirose M
    • Journal Title

      Eur J Pharmacol.

      Volume: 698 Pages: 87-94

    • DOI

      10.1016/j.ejphar.2012.10.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390297, KAKENHI-PROJECT-22590076, KAKENHI-PROJECT-23590374, KAKENHI-PROJECT-23593077, KAKENHI-PROJECT-23700588, KAKENHI-PROJECT-23790129
  • [Journal Article] Effects of TrkA inhibitory peptide on cancer-induced pain in a mouse melanoma model.2012

    • Author(s)
      Tabata M, Murata E, Ueda K, Kato-Kogoe N, Kuroda Y, Hirose M.
    • Journal Title

      J Anesth.

      Volume: in press

    • NAID

      10031070301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23593077
  • [Presentation] IGF-1Rの自己リン酸化部位由来ペプチドがMCF-7ヒト乳がん細胞に及ぼす影響2013

    • Author(s)
      黒田義弘,小越菜保子,田崎絵美,中瀬生彦,二木史朗,通山由美,廣瀬宗孝
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2013-09-11
    • Data Source
      KAKENHI-PROJECT-23593077
  • [Presentation] 細胞透過性オリゴペプチドによるA549ヒト肺線がん細胞に体する細胞増殖抑制、細胞毒性、及びアポトーシスへの影響2011

    • Author(s)
      黒田義弘、村田恵理、上田康陽、田崎絵美、小越菜保子、阿部峰大、宮本和英、中瀬生彦、二木史朗、通山由美、廣瀬宗孝
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-22590076
  • [Presentation] EGFRの自己リン酸化部位由来ペプチドのA549ヒト肺腺がん細胞における効果2011

    • Author(s)
      黒田義弘,村田恵理,上田康陽,田崎絵美,小越菜保子,阿部峰大,宮本和英,中瀬生彦,二木史朗,通山由美,廣瀬宗孝
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-23593077
  • [Presentation] 細胞透過性オリゴペプチドによるA549ヒト肺腺がん細胞に対する細胞増殖抑制、細胞毒性、及びアポトーシスへの影響2011

    • Author(s)
      黒田義弘
    • Organizer
      日本薬学会 第131年会
    • Place of Presentation
      ツインメッセ静岡(静岡市)
    • Year and Date
      2011-03-30
    • Data Source
      KAKENHI-PROJECT-22590076
  • [Presentation] EGFRの自己リン酸化部位由来ペプチドの A549ヒト肺腺がん細胞における効果2011

    • Author(s)
      黒田義弘,村田恵理,上田康陽,田崎絵美,小越菜保子,阿部峰大,宮本和英,中瀬生彦,二木史朗,通山由美,廣瀬宗孝
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都)
    • Data Source
      KAKENHI-PROJECT-23593077
  • [Presentation] EGFRの自己リン酸化部位由来ペプチドのA549ヒト肺腺がん細胞における効果2011

    • Author(s)
      黒田義弘
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-22590076
  • [Presentation] EGFRの自己リン酸化部位由来ペプチドのA549ヒト肺腺がん細胞における効果.2011

    • Author(s)
      黒田義弘、村田恵理、上田康陽、田崎絵美、小越菜保子、阿部峰大、宮本和英、中瀬生彦、二木史朗、通山由美、廣瀬宗孝
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-22590076
  • [Presentation] IGF-1Rの自己リン酸化部位由来ペプチドがMCF-7ヒト乳がん細胞に及ぼす影響

    • Author(s)
      黒田 義弘
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23593077
  • 1.  KOGOE Nahoko (60509115)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 2.  NAKAGAWA Terumichi (70025708)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  OHYAMA Hideki (90280685)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 4.  SHIBUKAWA Akimasa (30170913)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  TAGA Tooru (00025694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  HONDA Tetsuro (00025719)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  MATSUMOTO Osamu (10231599)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  中山 真彰 (10579105)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  山根木 康嗣 (00434944)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  山田 直子 (10319858)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  通山 由美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 12.  廣瀬 宗孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  宮本 和英
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  中瀬 生彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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