MUNAKATA Hiroshi 宗像浩

Researcher Number	90111294
External Links
Affiliation *help	2002 – 2008 : 近畿大学, 医学部, 教授 1998 – 2000 : 近畿大学, 医学部, 教授 1995 – 1997 : 東北大学, 医学部, 助教授 1986 – 1989 : 東北大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Functional biochemistry Except Principal Investigator Medical systems / Respiratory organ internal medicine / Pathological medical chemistry / Functional biochemistry / Gastroenterology
Keywords	Principal Investigator heme-regulatory motif / タンパク質細胞内輸送 / 5―アミノレブリン酸合成酵素 / ヘム調節モチーフ / Activation / mitochondria / 繊維化 / プロテオーム / ミトコンドリア / Myofibroblast … More Except Principal Investigator 腺腫様過形成 / 肝細胞癌 / NF-E2 / 早期肝癌 / MafK / GATA-1 / 純動脈相イメージング / Pure arterial phase imaging / 転写因子 / δ-アミノレブリン酸合成酵素 / Bach2 / Bach1 / 造影ハーモニック法 / Dysplastic nodule / Hepatocellular Carcinoma / cDNA / アイソザイム / Coded phase inversion harmonic / coproporphyrinogen oxidase / アデノウイルスベクター / Early Hepatocellular Carcinoma / Levovist / 結節内動脈血流 / endosonography / ヘム調節モチーフ / heme regulatory motif / δアミノレブリン酸合成酵素 / マイクロバブル / プロモーター / 超音波内視鏡検査 / Bach因子 / nodule-in-nodule / 結節内門脈血流 / コプロポルフィリノーゲンオキシダーゼ / GATA-2 / Immuno histochemical stainig / M-TAT細胞 / 5-aminolevulinate synthase / Kupffer cell / ハーモニックイメージング / δーアミノレブリン酸合成酵素 / Lung Cancer / 前癌病変 / 腫瘍血管構築 / Early hepatocellular carcinoma / 微小循環 / Decorin / 造影ハーモニックイメージング / 高分化型肝癌 / 超音波内視鏡 / 酵素精製 / 赤芽球 / Contrast Harmonic Imaging / Vascular imaging / 肝腫瘍 / Portal flow / 膵腫瘍 / 免疫組織染色 / p45 / 血管新生 / 遺伝子治療 / 造血細胞 / 5-アミノレブリン酸合成酵素 / microcirculation / GATA因子 / Kupffer細胞 / CD68 / contrast-enhanced harmonic mode / Sonazoid / 動脈血流 / Gene Therapy / Arterial flow / nodule-in-nodule HCC / Maf / デコリン / 造血前駆細胞 / 門脈血流 / Nodule-in-nodule HCC / メロンボポエチン / クッパー細胞 / 肺癌 / 白血病 / 超音波造影剤 / Neovascularization / dysplastic nodule / Adenovirus vector / 血流イメージ / 血球分化 Less

Newly Developed Image Analysis Method of Tumor Blood Flow : Separate Quantitative Analysis of Intranodular Arterial and Portal Blood Flow and Its Application to Research on Hepatocarcinogenesis
- Principal Investigator
  
  KUDO Masatoshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  Kinki University
Proteomic a-myofibroblastnalysis of activated- and inactivatedPrincipal Investigator
- Principal Investigator
  
  MUNAKATA Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kinki University
Hemodynamic and sinusoidal function change during multistep hepatocarcinogenesis : evaluation by contrast harmonic imaging
- Principal Investigator
  
  KUDO Masatoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical systems
- Research Institution
  Kinki University
Evaluation of pancreatic microvasculature by contrast-enhanced endosonography with high resolution -application to diagnosis and treatment-
- Principal Investigator
  
  KITANO Masayuki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical systems
- Research Institution
  Kinki University
Imaging Analysis and Molecular Mechanism of angio architectural Change of the Tumor During Multistep Human Hepatocarcinogenesis
- Principal Investigator
  
  KUDO Masatoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kinki University
Decorin inhibits the tumor growth, activates anti-tumor immunity, and suppresses tumor angiogenesis against lung cancer.
- Principal Investigator
  
  WATANABE Akira
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University
Molecular Mechanism of Posttranscriptional modification by HemePrincipal Investigator
- Principal Investigator
  
  MUNAKATA Hiroshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  KINKI UNIVERSITY
血球分化に関与する転写因子群の解析とその造血細胞腫瘍診断への応用
- Principal Investigator
  
  林典夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Regulation of erythroid differentiation by trnscription factors and heme
- Principal Investigator
  
  HAYASHI Norio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku University
血球分化に関与する転写因子群の解析とその造血細胞腫瘍診断への応用
- Principal Investigator
  
  HAYASHI Norio
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
赤芽球でのヘム生合成調節とその病態の研究-δ-アミノレブリン酸合成酵素の役割
- Principal Investigator
  
  林典夫
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
実験的ポルフィリン症の発症機構とヘム生合成系酵素の組織差に関する研究
- Principal Investigator
  
  林典夫
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Tohoku University

All 2007 2006

All Journal Article Presentation

[Journal Article] Analysis of plasma proteins that bind to glycosaminoglycans.2007
- Author(s)
  Saito A. Munakata H.
- Journal Title
  
  Biochim Biophys Acta. 1770(2)
  
  Pages : 241-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590873
[Journal Article] Connective tissue growth factor binds to fibronectin through the type I repeat modules and enhances the affinity of fibronectin to fibrin.2007
- Author(s)
  Yoshida K, Munakata H.
- Journal Title
  
  Biochim Biophys Acta. 1770(4)
  
  Pages : 672-80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590873
[Journal Article] Effects of ethyl-esterization, chain-lengths, unsaturation degrees, and hyperthermia on carcinostatic effect of omega-hydroxylated fatty acids.2007
- Author(s)
  Kusumoto K, Kageyama K, Matsuda T, Tomura TT, Munakata H, Tanaka H, Yazama F, Miwa N.
- Journal Title
  
  Exp Oncol. 29(2)
  
  Pages : 106-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590873
[Journal Article] Haeme-regulated degradation of delta-aminolevulinate synthase 1 in rat liver mitochondria.2007
- Author(s)
  Yoshino K, Munakata H, Kuge O, Ito A, Ogishima T.
- Journal Title
  
  J Biochem. 142(4)
  
  Pages : 453-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590873
[Journal Article] Combination therapy with PEG-IFN-alpha and 5-FU inhibits HepG2 tumor cell growth in nude mice by apoptosis of p532007
- Author(s)
  Hagiwara S, Kudo M, Munakata H, 他6名
- Journal Title
  
  Brit J Cancer 97
  
  Pages : 1532-1537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300176
[Journal Article] Combination therapy with PEG-IFN-alpha and 5-FU inhibits HepG2 tumour cell growth in nude mice by apoptosis of p53.2007
- Author(s)
  Hagiwara S, Kudo M, Nakatani T, Sakaguchi Y, Nagashima M, Fukuta N, Kimura M, Hayakawa S, Munakata H.
- Journal Title
  
  Br J Cancer. 97(11)
  
  Pages : 1532-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590873
[Journal Article] Effects of decorin on the expression of alpha-smooth muscle actin in a human myofibroblast cell line.2007
- Author(s)
  Nakatani T, Honda E, Hayakawa S, Sato M, Satoh K, Kudo M, Munakata H.
- Journal Title
  
  Mol Cell Biochem. 308(1)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590873
[Journal Article] Expression of decorin, p21, and a smooth muscle actin in quiescent human myofibroblast cell line.2006
- Author(s)
  Nakatani T, Honda E, Sato K, Kudo M, Munakata H
- Journal Title
  
  J Biochemistry (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500326
[Presentation] Connective tissue growth factor binds to fibronectin through the type I repeat modules and enhances the affinity of fibronectin to fibrin2007
- Author(s)
  Koji Yoshida, Hiroshi Munakata
- Organizer
  The 80th Annual Meeting of JBS The 30th Annual Meeting of MBSJ
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590873
[Presentation] Proteomic analysis of kidney cytosolic fraction of stroke-prone spontaneously hypertensive rats2007
- Author(s)
  Kana Ooshima Masaki Tabuchi Hideaki Higashino Mayumi Sato Eiko Honda Hiroshi Munakata
- Organizer
  The 80th Annual Meeting of JBS The 30th Annual Meeting of MBSJ
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590873
[Presentation] Changes of protein expression associated with morphological changes by forscolin.2007
- Author(s)
  Sumio Hayakawa, Hiroshi Munakata
- Organizer
  54th Kinki Branch of Japanese Biochemical Society Congress
- Place of Presentation
  Kyoto
- Year and Date
  2007-05-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590873
[Presentation] Effects of decorin on the expression of a-smooth muscle actin in a human myofibroblast cell line2007
- Author(s)
  Eiko Honda Hiroshi Munakata
- Organizer
  The 80th Annual Meeting of JBS The 30th Annual Meeting of MBSJ
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590873

1. HAYASHI Norio (00004606)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
2. KUDO Masatoshi (10298953)

# of Collaborated Projects : 4results

# of Collaborated Products : 2results
3. YOSIDA Koji (60230736)

# of Collaborated Projects : 2results

# of Collaborated Products : 2results
4. 峯岸直子 (40271895)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
5. FUKUNAGA Toyokazu (90330315)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
6. SAITO Akio (40153788)

# of Collaborated Projects : 2results

# of Collaborated Products : 1results
7. 小堺正史 (20004624)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
8. JIBIKI Takao

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
9. MURAKAMI Takamichi (20252653)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. NAGAI Tadashi (40237483)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. YAMAMOTO Kazuhiko (00166787)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. AMEMIYA Kana (30195929)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. WATANABE Akira (70220861)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. NARUMI Ko (30302219)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. EBINA Masahito (10280885)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. KAWASAKI Toshihiko (10330268)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. KITANO Masayuki (50314571)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. NAKATANI Tatsuya (40319661)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. MATSUDA Toshirou (80411586)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
20. HAYAKAWA Sumio (00368292)

# of Collaborated Projects : 1results

# of Collaborated Products : 3results
21. 古山和道 (80280874)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
22. 佐藤真弓 (90388512)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
23. 宮本清

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
24. 藤本浩

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
25. 松田外志朗

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

MUNAKATA Hiroshi 宗像 浩

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Proteomic a-myofibroblastnalysis of activated- and inactivatedPrincipal Investigator

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Molecular Mechanism of Posttranscriptional modification by HemePrincipal Investigator

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[Journal Article] Analysis of plasma proteins that bind to glycosaminoglycans.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Connective tissue growth factor binds to fibronectin through the type I repeat modules and enhances the affinity of fibronectin to fibrin.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Effects of ethyl-esterization, chain-lengths, unsaturation degrees, and hyperthermia on carcinostatic effect of omega-hydroxylated fatty acids.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Haeme-regulated degradation of delta-aminolevulinate synthase 1 in rat liver mitochondria.2007

Author(s)

MUNAKATA Hiroshi 宗像浩