ISHIMURA Kazunori 石村和敬

Researcher Number	90112185
Other IDs
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Affiliation (based on the past Project Information) *help	2011 – 2013: 徳島大学, ヘルスバイオサイエンス研究部, 教授 2007 – 2010: The University of Tokushima, The Institute of Health Bioscience, Professor 2006: 徳島大学, 大学院ヘルスバイオサイエンス研究科, 教授 2006: 徳島大学, 大学院ヘルスバイオサイエンス研究部, 教授 2004 – 2005: The University of Tokushima, Graduate School Institute of Health Biosciences, Professor, 大学院・ヘルスバイオサイエンス研究部, 教授 … More 1993 – 2003: 徳島大学, 医学部, 教授 1990: Dept. of Anatomy, The University of Tokushima School of Medicine Professor, 医学部, 教授 1987 – 1989: 大阪大学, 医学部, 助教授 1986: 阪大, 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator General anatomy (including Histology/Embryology) / General anatomy (including Histology/Embryology) Except Principal Investigator Metabolomics / Metabolomics / Urology / General pharmacology
Keywords	Principal Investigator 免疫組織化学 / ステロイドホルモン / 電子顕微鏡 / Steroid hormones / 5α-リダクターゼ / プロスタグランジン / 前立腺 / アロマターゼ / 神経ステロイド / 副腎 … More / Testis / Immunocytochemistry / 精巣 / 副腎皮質 / Prostaglandin / Electron microscopy / 5α-Reductase / 細胞化学 / 胎盤 / 肝臓 / C17-20リアーゼ / 17α-水酸化酵素 / Electron microscope / immunohistochemistry / 脳 / 下垂体 / Ovary / エストロゲン / 卵巣 / 酵素発現 / ステロイド合成酵素 / 卵巣摘除 / 神経細胞 / 海馬 / Adrenal cortex / ステロイド3β水酸基脱水素酵素 / カルスペクチン / 21水酸化酵素 / ステロイド17β水酸基脱水素酵素 / 腎髄質間質細胞 / ATP合成酵素 / enzyme expression / 5α-reductase / Purkinje cell / Bergmann glia / receptor / immunocytochemistry / neurosteroid / cerebellum / 発現 / 局在 / 培養 / 分子生物学 / 酵素 / 神経ステロイ / プルキンエ細胞 / バーグマングリア / 受容体 / 小脳 / Glial cell / 17β-Estradiol / Steroid synthesizing enzymes / Olfactory bulb / Neurosteroids / グリア / 17β-エストラジオール / 嗅球 / Phage library / Rat / Differentiation / 17β- Hydroxysteroid dehydrogenase / adrenal cortex / ghrelin / NO合成酵素 / バクテリオファージ / 抗体 / ファージライブラリー / ラット / 分化 / ステロイド17β-水酸基脱水素酵素 / Spinal cord / Cytochemistry / C17-20 lyase / 17α-Hydroxylase / 17β-Hydroxysteroid dehydrogenase / プロスタグランジンF合成酵素 / チトクロームb5 / C17-20リア-ゼ / 17α水酸化 / 17β-ヒドロキシステロイドデヒドロゲナーゼ / 脊髄 / 17β-ヒドロキシステロイド脱水素酵素 / (in press) / Placenta / Liver / Immunohistochemistry / Transcription factor / C17-20 1yase / l7alpha-Hydroxylase / PbX1 / アポトーシス / ライディッヒ細胞 / 転写調節因子 / Schwann cells / Adrenal gland / Prostate / Anterior pituitary / 5 alpha-Reductase / 精管 / 中枢神経 / シュワン細胞 / prostate / gonads / adrenal gland / pituitary gland / steroid hormones / electron microscopy / 5 alpha-reductase / 肥満細胞 / 5α-水素添加酵素 / 一酸化窒素(NO)合成酵素 / 性腺 / 5αリダクターゼ(水素添加酵素) / Ovulation / Androstenedione / Estrogen / C17-C20lyase / 17alpha-Hydroxylase / Aromatase / アンドロテンジオン / 間質腺細胞 / 内卵胞膜細胞 / 17αー水酸化酵素@C_<17>ーC_<20>リア-ゼ / 排卵 / プロゲステロン / アンドロステンジオン / C17ーC20切断酵素 / 17d水酸化 / アロマタ-ゼ / ニューロン新生 / エストロゲン受容体 / 細胞組織化学 … More Except Principal Investigator JVS mouse / carnitine / octn2 / JVSマウス / カルニチン / hypoglycemia / gene chip / fatty acid / insulin / 長鎖脂肪酸 / グルカゴン / インスリン / carintine transporter / octn 2 / THP / カルニチン輸送担体 / cellulose / milk / weaning period / death / セルロース / ラクトース / レプチン / 餓死 / 低血糖 / オレキシン / 固形食摂取 / ミルク摂取 / 離乳期 / mitochondria / OCTN-2 / influenza / インフルエンザ脳症 / インフルエンザウイルス / Gene Chip / OCTN 2 / JVS マウス / ミトコンドリア / OCTN2 / インフルエンザ / 低血糖症 / 2-DG uptake / glucagon / 膵ラ氏島 / 脂肪毒性 / 高血糖 / 膵β細胞 / 脂肪酸 / 2-DG取り込み / azoospermia / epidiymis / infertility / 閉塞性無精子症 / 全身性カルニチン欠乏マウス / 精巣上体 / 無精子症 / 妊よう性 / Molecular pharmacology / Neuronal cells / Cultured cells / Adernal chromaffin cells / カルシウム放出 / 神経成長因子 / ステロイドホルモン / カテコールアミン生合成 / カテコールアミン分泌 / 神経細胞への転換 / クロマフィン細胞の培養 / 分子薬理学 / 神経細胞 / 培養細胞 / 副腎クロマフィン細胞 Less

Histochemical and biochemical study of the production and function of neurosteroidPrincipal Investigator
- Principal Investigator
  
  ISHIMURA Kazunori
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  The University of Tokushima
Cytochemical and molecular biological analysis of neurosteroid synthesis and action mechanism in the hippocampusPrincipal Investigator
- Principal Investigator
  
  ISHIMURA Kazunori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  The University of Tokushima
Cytochemical and molecular biological analysis on the mechanisms of production and action of neurosteroids in the mouse cerebellum.Principal Investigator
- Principal Investigator
  
  ISHIMURA Kazunori
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  The University of Tokushima
Research on hypoglycemia caused by inhibition of orexin expression
- Principal Investigator
  
  KUWAJIMA Masamichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokushima
Cytochemical and cell biological study on the mechanism of synthesis and action of neurosteroids in the olfactory bulb.Principal Investigator
- Principal Investigator
  
  ISHIMURA Kazunori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  The University of Tokushima
Mechanism of encephalitis after influenza virus infection based on defect of β-oxidation in liver
- Principal Investigator
  
  KUWAJIMA Masamichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokushima
Cytochemical and molecular biological study on the control mechanisms of differentiation and function of steroid hormone synthesizing cells.Principal Investigator
- Principal Investigator
  
  ISHIMURA Kazunori
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  The University of Tokushima
Is lipotoxicity caused by the intracellular accumulation ofacyl CoA ?
- Principal Investigator
  
  KUWAJIMA Masamichi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokushima
Molecular biological and cytochemical study on the mechanisms of expression of steroid hormone synthesizing enzymes.Principal Investigator
- Principal Investigator
  
  ISHIMURA Kazunori
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  The University of Tokushima
Analysis of infertility in systemic carnitine deficient mouse (JVS mouse)
- Principal Investigator
  
  MURAKAMI Takashi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  The University of Tokushima
Cytochemical study on the mechanisms of expression and function of steroid hormone synthesizing enzymes.Principal Investigator
- Principal Investigator
  
  ISHIMURA Kazunori
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  The University of Tokushima
Cytochemical analysis on the mechanisms of biosynthesis and action of steroid hormones.Principal Investigator
- Principal Investigator
  
  ISHIMURA Kazunori
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  The University of Tokushima, School of Medicine
CONVERSION TO NEUROCYTE OF CULTURED ADRENAL CHROMAFFIN CELLS AND ITS MOLECULAR PHARMACOLOGICAL STUDY
- Principal Investigator
  
  HOUCHI Hitoshi, OKA Motoo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  THE UNIVERSITY OF TOKUSHIMA
Immunohistochemical analysis of steroid hormone biosynthesis and metabolismPrincipal Investigator
- Principal Investigator
  
  ISHIMURA Kazunori
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  The University of Tokushima School of Medicine
Immunocytochemical Study on the Mechanism of Biosynthesis and Secretion of Steroid HormonesPrincipal Investigator
- Principal Investigator
  
  ISHIMURA Kazunori
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  The University of Tokushima
  Osaka University
Immunocytochemical study on the mechanism of steroid hormone biosynthesis.Principal Investigator
- Principal Investigator
  
  ISHIMURA Kazunori
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Osaka University Medical School

All 2013 2012 2011 2009 2006

All Journal Article Presentation

[Journal Article] Nucling, a Novel Protein Associated with NF-κB, Regulates Endotoxin-induced Apoptosis in vivo2013
- Author(s)
  Sun Mi Kim、Takashi Sakai、Huy Van Dang、Nam Hoang Tran、Koji Ono、Kazunori Ishimura、Kiyoshi Fukui
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 153巻 Pages: 93-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590236
[Journal Article] The retinoic acid receptor agonist Am80 increases hippocampal ADAM10 in aged SAMP8 mice2013
- Author(s)
  Kazuyoshi Kitaoka, Noriyuki Shimizu, Koji Ono, Sachiko Chikahisa, Madoka Nakagomi, Koichi Shudo, Kazunori Ishimura, Hiroyoshi Sei, Kazuo Yoshizaki
- Journal Title
  
  Neuropharmacology
  
  Volume: 72 Pages: 58-65
- DOI
  10.1016/j.neuropharm.2013.04.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590236, KAKENHI-PROJECT-23730706
[Journal Article] The retinoic acid receptor agonist Am80 increases hippocampal ADAM10 in aged SAMP8 mice2013
- Author(s)
  Kazuyoshi Kitaoka、Noriyuki Shimizu、Koji Ono、Sachiko Chikahisa、Madoka Nakagomi、Koichi Shudo、Kazunori Ishimura、Hiroyoshi Séi、Kazuo Yoshizaki
- Journal Title
  
  Neuropharmacology
  
  Volume: 72巻 Pages: 58-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590236
[Journal Article] 統合失調症におけるD-アミノ酸酸化酵素の病態生理学的役割:ヒトおよびラット脳内における組織化学的発現解析2012
- Author(s)
  小野公嗣、宍戸裕二、朴煥埼、Rabab M. Abou El-Magd、鄭丞弼、頼田和子、佐野暢哉、有馬邦正、坂井隆志、石村和敬、福井清
- Journal Title
  
  ビタミン
  
  Volume: 86巻 Pages: 395-397
- NAID
  110009480124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590236
[Journal Article] Immunohistochemical analysis of aromatase and estrogen receptor α inrat hippocampus2011
- Author(s)
  Ono K, Kobayashi A, Ishimura K
- Journal Title
  
  Journal of physiological sciences
  
  Volume: 161
- Data Source
  KAKENHI-PROJECT-20590192
[Journal Article] 嗅球の神経ステロイド2009
- Author(s)
  清蔭恵美、樋田一徳、石村和敬
- Journal Title
  
  顕微鏡 44
  
  Pages: 215-218
- NAID
  130007788886
- Data Source
  KAKENHI-PROJECT-20590192
[Journal Article] Colocalization of prostaglandin F2α synthase receptor FP and prostaglandin F synthase-1 in the spinal cord.2009
- Author(s)
  Suzuki-Yamamoto T, Toida K, Sugimoto T, Ishimura K
- Journal Title
  
  Journal of Lipid Research 50
  
  Pages: 1996-2003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590192
[Presentation] Change in steroidogenic enzymes expression in the rat hippocampus after ovariectomy2012
- Author(s)
  Koji Ono, Kazunori Ishimura
- Organizer
  14th International Congress of Histochemistry and Cytochemistry
- Place of Presentation
  京都国際会議場（京都府）
- Data Source
  KAKENHI-PROJECT-23590236
[Presentation] 海馬におけるアロマターゼおよびエストロゲン受容体αの免疫組織化学的解析2011
- Author(s)
  小野公嗣、小林杏奈、石村和敬
- Organizer
  第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会
- Place of Presentation
  横浜
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-20590192
[Presentation] ラット海馬におけるアロマターゼおよびエストロゲン受容体αの免疫組織化学的解析2011
- Author(s)
  小野公嗣、小林杏奈、石村和敬
- Organizer
  第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会
- Place of Presentation
  横浜市
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-20590192
[Presentation] 免疫組織化学とin situ hybridization法を用いたヒトおよびラット脳内におけるD-アミノ酸酸化酵素の発現解析2009
- Author(s)
  小野公嗣、石村和敬
- Organizer
  第50回日本組織細胞化学会総会
- Place of Presentation
  大津市
- Year and Date
  2009-09-27
- Data Source
  KAKENHI-PROJECT-20590192
[Presentation] 免疫組織学並びにin situ hybridization法を用いたヒトおよびラット脳におけるD-アミノ酸酸化酵素の発現解析2009
- Author(s)
  小野公嗣、宍戸裕二、朴煥埼、Rabab M.Abou EI-Magd、鄭丞弼、頼田和子、佐野暢哉、有馬邦正、坂井隆志、石村和敬、福井清
- Organizer
  第50回日本組織細胞化学会総会・学術集会
- Place of Presentation
  大津
- Year and Date
  2009-09-27
- Data Source
  KAKENHI-PROJECT-20590192
[Presentation] Histochemical localization of nociceptin receptor in the mouse brain.2006
- Author(s)
  Ishimura K
- Organizer
  The Society for Neuroscience 36th Annual Meeting
- Place of Presentation
  Atlanta, USA
- Year and Date
  2006-10-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590185

1. KUWAJIMA Masamichi (00205262)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. ONO Koji (00548597)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. HOUCHI Hitoshi (00219156)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. OKA Motoo (60028298)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MURAKAMI Takashi (40210009)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SHINOHARA Yasuo (60226157)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TSUKAGUCHI Hiroyasu (60335792)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TOIDA Kazunori (40253405)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. YAMAMOTO Toshiko (60301313)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. ISHIMURA Yasuko (40035431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TANAKA Toshihiro (50292850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TOSHIMORI Kiyotaka (20094097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MIZUNO Akira (80219641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NOMA Yoshihiko (10218349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. DOI Toshio (60183498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SHIMABUKURO Michio (60271144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HIGUCHI Tomihiko (50035557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KUDO Kioshi (50144978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. NAKAYA Yutaka (50136222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. SEI Hiroyoshi (40206602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. YAMASHITA Keisuke (40166666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. MIYAMOTO Tadayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ISHIMURA Kazunori 石村 和敬

Research Projects

Research Products

Co-Researchers

Histochemical and biochemical study of the production and function of neurosteroidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cytochemical and molecular biological analysis of neurosteroid synthesis and action mechanism in the hippocampusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cytochemical and molecular biological analysis on the mechanisms of production and action of neurosteroids in the mouse cerebellum.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on hypoglycemia caused by inhibition of orexin expression

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cytochemical and cell biological study on the mechanism of synthesis and action of neurosteroids in the olfactory bulb.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of encephalitis after influenza virus infection based on defect of β-oxidation in liver

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cytochemical and molecular biological study on the control mechanisms of differentiation and function of steroid hormone synthesizing cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Is lipotoxicity caused by the intracellular accumulation ofacyl CoA ?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular biological and cytochemical study on the mechanisms of expression of steroid hormone synthesizing enzymes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of infertility in systemic carnitine deficient mouse (JVS mouse)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cytochemical study on the mechanisms of expression and function of steroid hormone synthesizing enzymes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cytochemical analysis on the mechanisms of biosynthesis and action of steroid hormones.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CONVERSION TO NEUROCYTE OF CULTURED ADRENAL CHROMAFFIN CELLS AND ITS MOLECULAR PHARMACOLOGICAL STUDY

Principal Investigator

Project Period (FY)

Research Category

ISHIMURA Kazunori 石村和敬