OHKAWA Kiyoshi 大川清

Researcher Number	90112812
Other IDs
Affiliation (based on the past Project Information) *help	2005 – 2006: 東京慈恵会医科大学, 医学部, 教授 1997 – 1998: 東京慈恵会医科大学, 医学部, 教授 1994 – 1995: JIKEI University School of Medicine, Professor, 医学部, 教授 1993: 東京慈恵会医科大学, 医学部, 助教授 1989 – 1990: 東京慈恵会医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Biomedical engineering/Biological material science / 内分泌・代謝学 / Neurochemistry/Neuropharmacology / Pathological medical chemistry Except Principal Investigator Experimental pathology / Kidney internal medicine
Keywords	Principal Investigator 神経伝達物質 / GABA / Proteome / Microarray / Artificial organ / Biomaterial / Bioreactor / ロテオーム / プロテオーム / マイクロアレイ … More / モデル臓器 / 生体材料 / バイオリアクター / diabetes / ubiquitination / glycation / EGF-receptor / 発癌 / グリケーション / ユビキチン / 上皮増殖因子リセプター / 上皮増殖因子 / 糖尿病 / 糖化反応 / ユビキチン化反応 / EGF受容体 / Pyridoxal phosphate / Neurotransmitter / Pyridoxal kinase / Vitamin B_6 / ピリドキサルリン酸 / ピリドキサルキナーゼ / ビタミンB_6 / 4-aminobutyraldehyde / Aldehyde dehydrogenase / 4-アミノブチルアルデヒド / 4ーアミノブチルアルデヒド / アルデヒド脱水素酵素 … More Except Principal Investigator Trinitrophenol / Interstitial nephritis / Cellular immunity / Ovalbumin / Cationic protein / Organ allergy / Renal tubular basement membrane / Hapten / 卵白アルブミン / trinitrophenol / 間質性腎炎 / 細胞性免疫 / 卵白アルブシン / 陽性荷電蛋白 / 臓器アレルギー / 腎尿細管基底膜 / ハプテン / イムノアッセイ / プロテアソーム / マルチユビキチン鎖 / ユビキチン / 細胞障害 / 急性腎不全 Less

Establishment and comprehensive gene analysis of cells derived from 3-dimensional radial flow bioreactor culture systemPrincipal Investigator
- Principal Investigator
  
  OHKAWA Kiyoshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Jikei University
急性腎不全の回復過程におけるユビキチン依存性蛋白質分解系の意義
- Principal Investigator
  
  柴崎敏昭
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyoritsu University of Pharmacy
  Jikei University School of Medicine
HYPERGLUCOSE CIRCUMSTANCE RETARDED EGF-RECEPTOR TURNOVERPrincipal Investigator
- Principal Investigator
  
  OHKAWA Kiyoshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  JIKEI UNIVERSITY SCHOOL OF MEDICINE
Regulatory mechanism (s) of pyridoxal kinase on production of neurotransmitters in the brain.Principal Investigator
- Principal Investigator
  
  OHKAWA Kiyoshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Jikei University School of Medicine
Experimental analysis on organ allergy of hapten-bound renal tubular basement membrane
- Principal Investigator
  
  JOH Kensuke
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  The JIKEI University School of Medicine
Purification and Characterization of a Rat Brain Aldehyde Dehydrogenase Able to Metabolize gamma-Amino Butyraldehyde to gamma-Aminobutyric AcidPrincipal Investigator
- Principal Investigator
  
  OHKAWA Kiyoshi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Jikei University School of Medicine

All 2007 2006 2005

All Journal Article Patent

[Journal Article] Association of extracellular matrix metalloproteinase inducer in endomtrial carcinoma with patient outcomes and clinicopathplogenesis using monoclonal antibody 12C32007
- Author(s)
  Ueda, K., Yamada, K., Ohkawa, K.et al.
- Journal Title
  
  Oncol.Rep. 17
  
  Pages: 731-735
- Data Source
  KAKENHI-PROJECT-17300160
[Journal Article] Purification and characterization of C-terminal truncated forms of histone H2A in monocytic THP-1 cells2007
- Author(s)
  Minami J, Ohkawa K. et al.
- Journal Title
  
  Int J Biochem Cell Biol.,Epub 2006 Aug 18. 39(1)
  
  Pages: 171-180
- Data Source
  KAKENHI-PROJECT-17300160
[Journal Article] Extracorporeal bioartifcial liver using the radial-flow bioreactor in treatment of fatal experimental hepatic encephalopathy2007
- Author(s)
  Kanai, H., Matsuura, T., Ohkawa, K., et al.
- Journal Title
  
  Artificial Organ 31
  
  Pages: 148-151
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300160
[Journal Article] Association of extracellular matrix metalloproteinase inducer in endomtrial carcinoma with patient outcomes and clinicopathplogenesis using monoclonal antibody 12C32007
- Author(s)
  Ueda, K., Yamada, K., Ohkawa, K., et al.
- Journal Title
  
  Oncol.Rep. 17
  
  Pages: 731-735
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300160
[Journal Article] Conformational change in the active center region of GST PI-1, due to binding of a synthetic conjugate of DXR with GSH, enhanced JNK-mediated apoptosis2007
- Author(s)
  Asakura, T., Ohkawa K., et al.
- Journal Title
  
  Apoptosis (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300160
[Journal Article] Purification and characterization of C-terminal truncated forms of histone H2A in monocytic THP-1 cells2007
- Author(s)
  Minami J, Ohkawa K., et al.
- Journal Title
  
  Int J Biochem Cell Biol., Epub 2006 Aug 18. 39(1)
  
  Pages: 1171-180
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300160
[Journal Article] Conformational change in the active center region of GST Pl-1,due to binding of a synthetic conjugate of DXR with GSH, enhanced JNK-mediated apoptosis2007
- Author(s)
  Asakura, T., Ohkawa K.et al.
- Journal Title
  
  Apoptosis (in press)
- Data Source
  KAKENHI-PROJECT-17300160
[Journal Article] Extracorporeal bioartificial liver using the radial-flow bioreactor in treatment of fatal experimental hepatic encephalopathy2007
- Author(s)
  Kanai, H., Matsuura, T., Ohkawa, K.et al.
- Journal Title
  
  Artificial Organ 31
  
  Pages: 148-151
- Data Source
  KAKENHI-PROJECT-17300160
[Journal Article] All-trans retinoic acid down-regulates human albumin gene expression through the inductionof C/EBP beta-LIP2006
- Author(s)
  Masaki, T., Matsuura, T., Ohkawa, K.et al.
- Journal Title
  
  Biochemical J. 397
  
  Pages: 345-353
- Data Source
  KAKENHI-PROJECT-17300160
[Journal Article] All-trans retinoic acid down-regulates human albumingene expression through the induction of C/EBP beta-LIP2006
- Author(s)
  Masaki, T., Matsuura, T., Ohkawa, K., et al.
- Journal Title
  
  Biochemical J. 397
  
  Pages: 345-353
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300160
[Journal Article] Relationship between expression of drug-resistance factors and drug sensitivity in normal human renal proximal tubular epithelial cells in comparison with renal cell carcinoma.2005
- Author(s)
  Asakura, T., Ohkawa, K., et al.
- Journal Title
  
  Oncol.Reports 14
  
  Pages: 601-607
- Data Source
  KAKENHI-PROJECT-17300160
[Patent] ガス混合装置及びガス混合法2006
- Inventor(s)
  松浦知和, 大川清他
- Industrial Property Rights Holder
  松浦知和, 大川清他
- Industrial Property Number
  2006-050548
- Filing Date
  2006-02-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300160
[Patent] プロテアソーム阻害剤耐性細胞の治療用組成物,治療用キット、及びプロテアソーム阻害剤耐性癌の治療用化合物のスクリーニング方法2005
- Inventor(s)
  大川清
- Industrial Property Rights Holder
  大川清
- Industrial Property Number
  2005-180494
- Filing Date
  2005
- Data Source
  KAKENHI-PROJECT-17300160
[Patent] 新規血漿糖タンパク質の産生方法2005
- Inventor(s)
  大川清
- Industrial Property Rights Holder
  大川清
- Industrial Property Number
  2005-277428
- Filing Date
  2005
- Data Source
  KAKENHI-PROJECT-17300160

1. ASAKURA Tadashi (30138705)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. TAKADA Koji (30179452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. MATSUDA Makoto (80056506)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. JOH Kensuke (10057086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HAYASHI Takashi (90221506)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MATSUFUJI Senya (50192753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MATSUURA Tomokazu (30199749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. AOKI Katsuhiko (80328278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 柴崎敏昭 (60100921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OHKAWA Kiyoshi 大川 清

Research Projects

Research Products

Co-Researchers

Establishment and comprehensive gene analysis of cells derived from 3-dimensional radial flow bioreactor culture systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

急性腎不全の回復過程におけるユビキチン依存性蛋白質分解系の意義

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HYPERGLUCOSE CIRCUMSTANCE RETARDED EGF-RECEPTOR TURNOVERPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulatory mechanism (s) of pyridoxal kinase on production of neurotransmitters in the brain.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental analysis on organ allergy of hapten-bound renal tubular basement membrane

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Purification and Characterization of a Rat Brain Aldehyde Dehydrogenase Able to Metabolize gamma-Amino Butyraldehyde to gamma-Aminobutyric AcidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Association of extracellular matrix metalloproteinase inducer in endomtrial carcinoma with patient outcomes and clinicopathplogenesis using monoclonal antibody 12C32007

Author(s)

Journal Title

Data Source

[Journal Article] Purification and characterization of C-terminal truncated forms of histone H2A in monocytic THP-1 cells2007

Author(s)

Journal Title

Data Source

[Journal Article] Extracorporeal bioartifcial liver using the radial-flow bioreactor in treatment of fatal experimental hepatic encephalopathy2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Association of extracellular matrix metalloproteinase inducer in endomtrial carcinoma with patient outcomes and clinicopathplogenesis using monoclonal antibody 12C32007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Conformational change in the active center region of GST PI-1, due to binding of a synthetic conjugate of DXR with GSH, enhanced JNK-mediated apoptosis2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Purification and characterization of C-terminal truncated forms of histone H2A in monocytic THP-1 cells2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Conformational change in the active center region of GST Pl-1,due to binding of a synthetic conjugate of DXR with GSH, enhanced JNK-mediated apoptosis2007

Author(s)

Journal Title

Data Source

[Journal Article] Extracorporeal bioartificial liver using the radial-flow bioreactor in treatment of fatal experimental hepatic encephalopathy2007

Author(s)

Journal Title

Data Source

[Journal Article] All-trans retinoic acid down-regulates human albumin gene expression through the inductionof C/EBP beta-LIP2006

Author(s)

Journal Title

Data Source

OHKAWA Kiyoshi 大川清