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kirino takaaki
桐野 高明
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Alternative Names
KIRINO Takaaki 桐野 高明
桐野 高明 キリノ タカアキ
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Researcher Number
90126045
Other IDs
External Links
Affiliation (Current)
2023: 国立研究開発法人国立国際医療研究センター, その他部局等, その他
Affiliation (based on the past Project Information)
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2009: 国立国際医療研究センター, 理事長
2007: 国立国際医療センター, 研究所, 所長
2002 – 2003: 東京大学, 医学部附属病院, 教授
2000 – 2001: The University Hospital, Neurosurgery, Professor, 医学部・附属病院, 教授
1999 – 2000: 東京大学, 医学部, 教授
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1999: 東京大学, 医学部・付属病院, 教授
1996 – 1998: University of Tokyo, Faculty of Medicine, Department of Neurosurgery, Proferror, 医学部・附属病院, 教授
1996: 東京大学, 医学部附属病院, 教授
1994 – 1995: 東京大学, 医学部, 教授
1993 – 1995: 東京大学, 医学部(病), 教授
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Review Section/Research Field
Principal Investigator
Cerebral neurosurgery
Except Principal Investigator
Cerebral neurosurgery
/
Cerebral neurosurgery
/
広領域
Keywords
Principal Investigator
脳虚血 / 海馬 / 細胞死 / 砂ネズミ / ストレス蛋白 / ユビキチン / cerebral ischemia / Cerebral ischemia / Hippocampus / 遅発性神経細胞死
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/ 免疫染色 / Mongolian gerbil / Stress protein / Ubiquitin / アポトーシス / delayed neuronal death / GLT-1 / 蛋白合成 / シナプス / neuronal death / stress response / protein synthesis / excitotoxin / presynaptic terminal / ubiqutin / Cell daeth / Protein synthesis / Synapse / ストレス応答 / 神経細胞死 / 抗体 / 変性蛋白 / Stress response / Cell death / Immunostaining / 神経細胞 / 蛋白分解 / ラジオイムノアッセイ / ELISA / in situ hybridization / ubiquitin / apoptosis / cell death / neuron / hippocampus / proteolysis / グルタミン酸トランスポーター / ノックアウトマウス / glutamate transporter / knockout mice / gerbil / 虚血耐性 / 遺伝子発現情報 / MAPキナーゼ / 遺伝子発現情報解析 / プロテオミクス / Delayed neuronal death / Ischemic Tolerance / mRNA Expression Analysis / Stress Protein / MAP kinase / Apoptosis
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Except Principal Investigator
アポトーシス / 脳虚血 / カルシウム / radiosurgery / 一酸化窒素 / 脳温度 / 移植 / 再生医学 / 移植・再生医学 / 虚血ニューロン死 / 興奮毒性 / 遠隔効果 / 虚血耐性 / 軽微低脳温 / グリア細胞 / 赤血球変形能 / 転写制御因子 / グルタミン酸受容体 / FK506 / プログラム死 / スライス培養 / 加齢 / AP-1 / 虚血ストレス / クルシウム / ユビキチン / 海馬スライス / 虚血性ニューロン死 / グルタミン酸放出 / 低脳温 / 蛋白質代謝 / 遠隔領域障害 / Ischemic neuronal death / Excitotoxicity / Remote effects / Resistance to ischemia / Mild hypothermia / Glial cells / Red cell deformability / Transcription factor / ガンマナイフ / ラジオサージェリー / 生物学的効果 / 臨床応用 / 脳動静脈奇形 / 聴神経腫瘍 / 髄膜腫 / 神経細胞 / 生物学的影響 / γナイフ(ガンマナイフ) / AUM(動静脈奇型) / 脳腫瘍 / Gamma knife / biological effect / clinical results / acoustic tumor / arteriovenous malformation / meningioma / グリオーマ / カルシニューリン / プロテアソーム / ワクチン療法 / differential display PCR / Apoptosis / glioma / calcineurin / proteasome / 脳血管攣縮 / クモ膜下出血 / 平滑筋細胞障害 / ATP / cyclic GMP / 平滑筋代謝 / Intracellular calcium / Basilar artery / Dog / Cerebral arterial spasm / Viability / Smooth muscle / Subarachnoid hemorrhage / Fura-2 / 脳疾患 / 遺伝子治療 / 細胞療法 / 遺伝子解析 / CNS disease / Gene therapy / Cell therapy / Genetic analysis
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Research Projects
(
12
results)
Research Products
(
2
results)
Co-Researchers
(
34
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Skin-derived stem cells transplanted into cerebral ischemia and injured hypoglossal nerve in mice
Principal Investigator
TAKAI Keisuke
Project Period (FY)
2007 – 2009
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
The University of Tokyo
Genome-wide expression analysis of ischemic neuronal injury based on functional genomics and proteomics
Principal Investigator
Principal Investigator
KIRINO Takaaki
Project Period (FY)
2001 – 2003
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Cerebral neurosurgery
Research Institution
The University of Tokyo
Development of gene therapy and cell therapy for central nervous system diseases
Principal Investigator
YOSHIDA Jun
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (A).
Research Field
Cerebral neurosurgery
Research Institution
Nagoya University
Elucidation of the Mechanisms for Glutamate Release in Ischemic Neuronal Injury
Principal Investigator
Principal Investigator
KIRINO Takaaki
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Cerebral neurosurgery
Research Institution
The University of Tokyo
The role of ubiquitin in neuronal apoptosis
Principal Investigator
Principal Investigator
KIRINO Takaaki
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Cerebral neurosurgery
Research Institution
The University of Tokyo
局所脳虚血において発生する一酸化窒素の神経毒性ならびに血流増加作用の温度依存性
Principal Investigator
MORIKAWA Eiharu
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
The University of Tokyo
Vaccination therapy against malignant glioma using apoptosis-inducing genes
Principal Investigator
ASAI Akio
Project Period (FY)
1995 – 1997
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Cerebral neurosurgery
Research Institution
The University of Tokyo
Stress Response in Cerebral Ischemia and the Role of Ubiquitin
Principal Investigator
Principal Investigator
KIRINO Takaaki
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Cerebral neurosurgery
Research Institution
University of Tokyo
脳血管攣縮の平滑筋細胞障害におけるアポトーシスの関与とサイトカインの効果の研究
Principal Investigator
KIM Phyo
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
Dokkyo University School of Medicine
The University of Tokyo
The mechanisms of ischemic neuronal death and its treatment.
Principal Investigator
KATAOKA Kiyoshi
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
広領域
Research Institution
Ehime University School of Medicine
Mechanism of Neuronal Cell Death following Cerebral Ischemia
Principal Investigator
Principal Investigator
KIRINO Takaaki
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
Cerebral neurosurgery
Research Institution
University of Tokyo
Analysis of biological effect and clinical result of radiosurgery
Principal Investigator
SUZUKI Ichiro
,
河本 俊介
Project Period (FY)
1993 – 1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Cerebral neurosurgery
Research Institution
University of Tokyo
All
2007
2006
All
Presentation
[Presentation] Skin-derived stem cells transplanted into injured hypoglossal nerve in mice
2007
Author(s)
Keisuke Takai, Hitoshi Okochi, Nobutaka Kawahara, Takaaki Kirino, Nobuhito Saito
Organizer
NEURO-COE retreat
Place of Presentation
Hakone
Year and Date
2007-06-17
Data Source
KAKENHI-PROJECT-19591664
[Presentation] Skin-derived stem cells transplanted into cerebral ischemia in mice
2006
Author(s)
Keisuke Takai, Hitoshi Okochi, Nobutaka Kawahara, Takaaki Kirino, Nobuhito Saito
Organizer
NEURO-COE retreat
Place of Presentation
Hakone
Year and Date
2006-06-30
Data Source
KAKENHI-PROJECT-19591664
# of Projects (Dsc)
# of Projects (Asc)
1.
IDE Takafumi
(40262000)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
2.
NOBUTAKA Kawahara
(60214673)
# of Collaborated Projects:
3 results
# of Collaborated Products:
2 results
3.
SAITO Nobuhito
(60262002)
# of Collaborated Projects:
2 results
# of Collaborated Products:
2 results
4.
FUJIMAKI Takamitu
(80251255)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
5.
ASAI Akio
(50231858)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
MORIKAWA Eiharu
(90251256)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
7.
OKOUTI Hitoshi
(30185235)
# of Collaborated Projects:
2 results
# of Collaborated Products:
2 results
8.
SUZUKI Ichiro
(30162928)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
9.
TAKAI Keisuke
(70376424)
# of Collaborated Projects:
1 results
# of Collaborated Products:
2 results
10.
KATAOKA Kiyoshi
(20025589)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
YONEDA Yukio
(50094454)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
FUJISHIMA Masatoshi
(80038760)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
HAYAKAWA Toru
(20135700)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
TAMURA Akira
(80111532)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
MORIMOTO Tadashi
(20230154)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
SASAKI Tomio
(10134561)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
KURITA Hiroki
(70262003)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
MATSUNO Akira
(00242058)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
KIM Phyo
(90231290)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
20.
UEKI Keisuke
(20302705)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
21.
YOSHIDA Jun
(40158449)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
22.
WAKABAYASHI Toshihiko
(50220835)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
23.
MIZUNO Masaaki
(70283439)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
24.
KAWASE Takeshi
(40095592)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
25.
KURISU Kaoru
(70201473)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
26.
HAMAKUBO Takao
(90198789)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
27.
ABURATANI Hiroyuki
(10202657)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
28.
岡田 安弘
(40073069)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
29.
桐野 高明
(10161605)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
30.
河本 俊介
(00231275)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
31.
川合 謙介
(70260924)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
32.
浜窪 隆雄
(90198797)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
33.
豊田 富勝
(00251257)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
34.
KUCHINO Yoshiyuki
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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