MORITA Takashi 森田隆司

… Alternative Names

森田隆司モリタタカシ

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Researcher Number	90128108
Other IDs
Affiliation (based on the past Project Information) *help	2009 – 2010: Meiji Pharmaceutical University, 薬学部, 客員研究員 2006 – 2008: 明治薬科大学, 薬学部, 教授 2000 – 2004: 明治薬科大学, 薬学部, 教授 1996 – 1997: 明治薬科大学, 薬学部, 教授 1991: 明治薬科大学, 薬剤学科, 教授 … More 1988 – 1990: 明治薬科大学, 薬学科, 教授 1987: 明治薬科大学, 薬剤学科, 教授 1986: 明治薬科大学, 教授 1986: 明薬大, 薬学部, 教授 Less
Review Section/Research Field	Principal Investigator 物質生物化学 / Structural biochemistry / Structural biochemistry / Biological pharmacy Except Principal Investigator 物質生物化学
Keywords	Principal Investigator 組織因子 / Glaドメイン / VEGF / 蛋白質 / 神経毒蛋白質 / 外因系血液凝固 / VII因子 / EGFドメイン / 血液凝固 / マグネシウム … More / ビタミンK / 血友病 / 凝固第IX因子 / 血液凝固反応 / 血管内皮増殖因子 / 血管透過性 / 生体生命情報学 / 分子認識 / ゲノム / 生体分子 / 生理活性 / プロテアーゼインヒビター / タンパク質 / プロテオーム / 血管内皮細胞 / トロンボプラスチン / 血液凝固第【VII】因子 / リポ多糖 / セリンプロテアーゼ / C因子 / カブトガニ血球 / 血球凝固反応 / 凝固カスケード機構 / ビタミンK依存性凝固因子 / Gla-ドメイン / カルシウム結合部位 / 第VII因子 / 血栓毒蛋白質 / C型レクチン様蛋白質 / コブラ科蛇 / クサリヘビ科蛇毒 / コブラ科蛇毒 / neurotoxin / thrombo-toxin / C-type lectin-like protein / Elapidae snake / Viperidae snake / 止血血栓 / 結晶構造 / 生体膜リン脂質 / IX / X-bp / IX-bp / 凝固IX因子 / X因子 / X因子結合タンパク質 / carboxyglutamic acid (Gla) domains / factor X / factor IX / Mg^<2+> ions / collagen receptor / glycoprotein(GP) Ia / IIa / EMS16 … More Except Principal Investigator VII因子 / IX因子 / 血液凝固反応 / 組織因子 / X因子 / 異常フィブリノーゲン / プロテインCインヒビター / β_2ーグリコプロテイン / 糖鎖ペプチド / β_2ー糖タンパク質 / C4b結合タンパク質 / フィブリノ-ゲン異常分子 / プロテインCインヒビタ- / VIII因子 / プロテインC / IX / 白血病性芽球 / デキストラン硫酸 / 蛍光性ペプチド基質 / 血液凝固因子 / セリンプロテアーゼ / 7-アミノー4-メチルクマリン / Xla因子 / 【VII】因子 / 【IX】因子 / 【X】因子 / 7-アミノ-4-メチルクマリン / α-スロンビン / Blooc clotting protease / Factor XIa / <alpha>-Thrombin / Factor Xa / Factor XIIa / Plasma kallikrein / Protein Ca Less

Comprehensive study to explore new physiologically active proteins in the snake venoms in the tropical and subtropical regionsPrincipal Investigator
- Principal Investigator
  
  MORITA Takashi
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Meiji Pharmaceutical University
Studies on the structure and function of new vascular endothelial growth factorsPrincipal Investigator
- Principal Investigator
  
  MORITA Takashi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Meiji Pharmaceutical University
Studies on the crystal structure of clotting factors and its binding proteins.Principal Investigator
- Principal Investigator
  
  MORITA Takashi
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  MEIJI PHARMACEUTICAL UNIVERSITY
Investigation and biochemical study of novel neurotoxins and thrombo-toxin from the venoms of Elapidae and Viperidae snakes.Principal Investigator
- Principal Investigator
  
  MORITA Takashi
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  MEIJI PHARMACEUTICAL UNIVERSITY
血漿Mgイオンが関与した新しい血液凝固カスケード機構の研究Principal Investigator
- Principal Investigator
  
  森田隆司
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Meiji Pharmaceutical University
外因系血液凝固開始系の再構成及び開始因子の機能発現の解析Principal Investigator
- Principal Investigator
  
  森田隆司
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Meiji Pharmaceutical University
血液凝固の分子機構の研究
- Principal Investigator
  
  岩永貞昭
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
血液凝固の分子機構の研究
- Principal Investigator
  
  IWANAGA Sadaaki
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
血液凝固の分子機構の研究
- Principal Investigator
  
  岩永貞昭
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
ビタミンK依存性凝固因子のGla-domainの機能Principal Investigator
- Principal Investigator
  
  森田隆司
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Meiji Pharmaceutical University
血管内皮細胞由来の織識因子(トロンボプラスチン)の分子構造Principal Investigator
- Principal Investigator
  
  森田隆司
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Meiji Pharmaceutical University
リポ多糖感受性セリンプロテアーゼチモーゲンの活性化機構Principal Investigator
- Principal Investigator
  
  森田隆司
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Meiji Pharmaceutical University
Development and Application of Fluorogenic Peptide Substrates for Determination fo Blood Clotting Proteases
- Principal Investigator
  
  IWANAGA Sadaaki
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  物質生物化学
- Research Institution
  Kyushu University

All 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 1996 Other

All Journal Article Presentation Book Patent

[Book] Toxins and Hemostasis.2010
- Author(s)
  Kini RM, Clemetson KJ, Markland FS, Mclane MA, Morita T (Editors.)
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-19406002
[Book] Toxins and Hemostasis2010
- Author(s)
  Takashi Morita (Editor)
- Total Pages
  797
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-19406002
[Book] 日本血栓止血学会誌(血液凝固X因子-その周辺と展望-, 20巻5号)2009
- Author(s)
  森田隆司
- Total Pages
  7
- Data Source
  KAKENHI-PROJECT-19406002
[Book] Snake Venoms and Other Toxic Components Affecting Thrombosis and Hemostasis. In: Recent Advances in Thrombosis and Hemostasis 2008. (Tanaka K, Davie EW eds)2008
- Author(s)
  Yamazaki Y, Morita T
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-18370048
[Book] Recent Advances in Thrombosis and Hemostasis 2008.(Tanaka K, Davie EW eds.)(Snake Venoms and Other Toxic Components Affecting Thrombosis and Hemostasis.)2008
- Author(s)
  Yamazaki Y, Morita T
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-19406002
[Book] Molecular and functional diversity of vascular endothelial growth factors2006
- Author(s)
  Yamazaki Y, Morita T
- Publisher
  Mol. Divers.
- Data Source
  KAKENHI-PROJECT-18370048
[Book] Handbook of Proteolytic Enzymes 2nd ed.2004
- Author(s)
  森田隆司
- Total Pages
  3
- Publisher
  Academic Press, Amsterdam
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Book] Current Drug Targets - Cardiovascular and Haematological Disorders2004
- Author(s)
  森田隆司
- Total Pages
  7
- Data Source
  KAKENHI-PROJECT-13480197
[Book] Toxicon2004
- Author(s)
  森田隆司
- Total Pages
  5
- Data Source
  KAKENHI-PROJECT-13480197
[Book] Handbook of Proteolytic Enzymes 2nd ed.2004
- Author(s)
  森田隆司
- Total Pages
  3
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] VKORの立体構造とワルファリンの作用機序2010
- Author(s)
  森田隆司
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 21 Pages: 395-362
- NAID
  10026711741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19406002
[Journal Article] Structural divergence of cysteine-rich secretary proteins in snake venoms.2009
- Author(s)
  Matsunaga Y, Yamazaki Y, Hyodo F, Nozaki M, Morita T
- Journal Title
  
  J.Biochem. 145
  
  Pages: 365-375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19406002
[Journal Article] VEGF-A and VEGF-F evoke distinct changes in vascular ultrastructure.2009
- Author(s)
  Matsunaga Y, Yamazaki Y, Suzuki H, Morita T
- Journal Title
  
  Biochem. Biophys. Res. Commun. 379
  
  Pages: 872-875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370048
[Journal Article] Snake venom vascular endothelial growth factors (VEGF-Fs) exclusively vary their structures and functions among species2009
- Author(s)
  Yamazaki, Y., Matsunaga, Y., Tokunaga, Y., Obayashi, S., Saito, M., Morita, T.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 9885-9891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19406002
[Journal Article] Anticoagulant mechanism of factor IX/X-binding protein isolated frm the venom of Trimerresurus flavoviridis.2009
- Author(s)
  Ishikawa M, Kumashiro M, Yamazaki Y, Atoda H, Morita T
- Journal Title
  
  J.Biochem. 145
  
  Pages: 123-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19406002
[Journal Article] VEGF-A and VEGF-F evoke distinct changes in vascular ultrastructure.2009
- Author(s)
  Matsunaga Y, Yamazaki Y, Suzuki H, Morita T
- Journal Title
  
  Biochem.Biophys.Res.Commun. 379
  
  Pages: 872-875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19406002
[Journal Article] Snake venom vascular endothelial growth factors(VEGF-Fs)exclusively vary their structures and functions among species2009
- Author(s)
  Yamazaki Y, Matsunaga Y, Tokunaga Y, Obayashi S, Saito M, Morita T.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 9885-9891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19406002
[Journal Article] Snake venom vascular endothelial growth factors (VEGF-Fs) exclusively vary their structures and functions among species.2009
- Author(s)
  Yamazaki Y, Matsunaga Y, Tokunaga Y, Obayashi S, Saito M, Morita T
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 9885-9891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19406002
[Journal Article] Structures of pseudechetoxin and pseudecin, two snake-venom cysteine-rich secretory proteins that target cyclic nucleotide-gated ion channels : implications for movement of the C-terminal cysteine-rich domain.2008
- Author(s)
  Suzuki N, Yamazaki Y, Brown RL, Fujimoto Z, Morita T, Mizuno H
- Journal Title
  
  Acta Cryst. D64
  
  Pages: 1034-1042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19406002
[Journal Article] Adenovirus serotype 5 hexon mediates liver gene transter.2008
- Author(s)
  Waddington SN, McVey JH, Bhella D, Parker AL, Barker K, Atoda H, Pink R, Buckley SMK, Greig JA, Denby L, Custers J, Morita T, Francischetti IMB, Monteiro RQ, Barouch DH, Rooijen NV, Napoli C, Havenga MJE, Nicklin SA, Baker AH
- Journal Title
  
  Cell 132
  
  Pages: 397-409
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19406002
[Journal Article] Catalytically inactive phospholipase A2 homologue binds to vcascular endothelial growth factor receptor-2 via a C-terminal loop region.2008
- Author(s)
  Fujisawa D, Yamazaki Y, Lomonte B, Morita T
- Journal Title
  
  Biochem. J. 411
  
  Pages: 515-522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370048
[Journal Article] Catalytically inactive phospholipase A2 homologue binds to vcascular endothelial growth factor receptor-2 via a C-terminal loop region.2008
- Author(s)
  Fujisawa D, Yamazaki Y, Lomonte B, Morita T
- Journal Title
  
  Biochem.J. 411
  
  Pages: 515-522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19406002
[Journal Article] Adenovirus serotype 5 hexon mediates liver gene transter.2008
- Author(s)
  Waddington SN, McVey JH, Bhella D, Parker AL, Barker K, Atoda H, Pink R, Buckley SMK, Greig JA, Denby L, Custers J, Morita T, Francischetti IMB, Monteiro RQ, Barouch DH, Rooijen NV, Napoli C, Havenga MJE, Nicklin SA, Baker AH
- Journal Title
  
  Cell 132
  
  Pages: 397-409
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370048
[Journal Article] PIVKA-IIの生化学2007
- Author(s)
  森田隆司
- Journal Title
  
  肝胆膵 54
  
  Pages: 459-463
- Data Source
  KAKENHI-PROJECT-19406002
[Journal Article] Augmentation of vascular permeability of VEGF is enhanced by KDR-binding proteins.2007
- Author(s)
  Yamazaki Y, Nakano Y, Imamura T, Morita T
- Journal Title
  
  Biochem. Biophys. Res. Commun. 355
  
  Pages: 693-699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370048
[Journal Article] PIVKA-IIの生化学2007
- Author(s)
  森田隆司
- Journal Title
  
  肝胆膵 54
  
  Pages: 459-463
- Data Source
  KAKENHI-PROJECT-18370048
[Journal Article] Augmentation of vascular permeability of VEGF is enhanced by KDR-binding proteins.2007
- Author(s)
  Yamazaki Y, Nakano Y, Imamura T, Morita T
- Journal Title
  
  Biochem.Biophys.Res.Commun. 355
  
  Pages: 693-699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19406002
[Journal Article] Age-and gender-related differences of plasma prothrombin activity levels.2007
- Author(s)
  Sakata T, Okamoto A, Morita T, Kokubo Y, Sato K, Okayama A, Tomoike H, Miyata T
- Journal Title
  
  Thromb.Haemost. 97
  
  Pages: 1052-1053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19406002
[Journal Article] Different contributions of polymorphism in VKORC1 and CYP2C9 to intra- and inter- population differences in maintenance dose of warfarin in Japanese, Caucasians and African- Americans.2006
- Author(s)
  Takahashi H, Wilkinson GR, Nutescu EA, Morita T, Ritchie MD, Scordo MG, Pengo V, Barban M, Padrini R, Ieiri I, Otsubo K, Kashima T, Kimura S, Kijima S, Echizen H
- Journal Title
  
  Pharmacogenetics Genomics 16
  
  Pages: 101-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370048
[Journal Article] The vascular endothelial growth factor VEGF165 induces perlecan synthesis via VEGF receptor-2 in cultured human brain microvascular endothelial cells.2006
- Author(s)
  Kaji T, Yamamoto C, Oh-i M, Fujiwara Y, Yamazaki Y, Morita T, Plaas AH, Wight TN
- Journal Title
  
  Biochim. Biophys. Acta. 1760
  
  Pages: 1465-1474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370048
[Journal Article] Localization of heparin- and neuropilin-1-recognition sites of viral VEGFs.2006
- Author(s)
  Tokunaga Y, Yamazaki Y, Morita T
- Journal Title
  
  Biochem. Biophys. Res. Commun. 348
  
  Pages: 957-962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370048
[Journal Article] Characterization of a monoclonal antibody B1 that recognizes phosphorylated Ser-158 in the activation peptide region of human coagulation factor IX.2006
- Author(s)
  Atoda H, Yokota E, Morita T
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 9314-9320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370048
[Journal Article] A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.2006
- Author(s)
  Suzuki-Inoue K, Fuller GLJ, Garcia A, Eble JA, Pohlmann S, Inoue O, Gartner TK, Hughan SC, Pearce AC, Laing GD, Theakston RD, Schweighoffer E, Zitzmann N, Morita T, Tybulewicz VLJ, Ozaki Y, Watson SP
- Journal Title
  
  Blood 107
  
  Pages: 542-549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370048
[Journal Article] Structures and functions of snake venom CLPs (C-type lectin-like proteins) with anticoagulant-, procoagulant-, and platelet-modulating activities.2005
- Author(s)
  森田隆司
- Journal Title
  
  Toxicon 45
  
  Pages: 1099-1114
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Crystal structures of novel vascular endothelial growth factors(VEGF) from snake venoms. : Insight into selective VEGF binding to kinase insert domain-containing receptor but not to fms-like tyrosine kinase-1.2005
- Author(s)
  Suto, K., Yamazaki, Y., Morita, T., Mizuno, H.
- Journal Title
  
  J.Biol.Chem 280
  
  Pages: 2126-2131
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Structure and function of snake venom cysteine-rich secretory proteins.2004
- Author(s)
  Y.Yamazaki, T.Morita
- Journal Title
  
  Toxicon 44
  
  Pages: 227-231
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] C-type lectin-related Proteins of Snake venoms.2004
- Author(s)
  森田隆司
- Journal Title
  
  Current Drug Targets - Cardiovascular and Haematological Disorders 4
  
  Pages: 357-373
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] C-type lectin-related Proteins of Snake venoms.2004
- Author(s)
  T.Morita
- Journal Title
  
  Current Drug Targets-Cardiovascular and Haematological Disorders 4
  
  Pages: 357-373
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Use of Snake Venom Inhibitors in Studies of the Function and Tertiary Structure of Coagulation Factors.2004
- Author(s)
  T.Morita
- Journal Title
  
  Int.J.Hematol. 79
  
  Pages: 123-129
- NAID
  80016514406
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Use of snake venom inhibitors in studies of the function and tertiary structure of coagulation factor.2004
- Author(s)
  森田隆司
- Journal Title
  
  International Journal of Hematology 79
  
  Pages: 123-129
- NAID
  80016514406
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Crystal structure of EMS16 in complex with the integrin α2-I domain.2004
- Author(s)
  Horii, K., Okuda, D., Morita, T., Mizuno, H.
- Journal Title
  
  J.Mol.Biol. 341
  
  Pages: 519-527
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Characterization and preliminary crystallographic studies of EMS16,an antagonist of collagen receptor (GPIa/IIa) from the venom of Echis multisquamatus.2003
- Author(s)
  Okuda D., Horii K., Mizuno H., Morita T.
- Journal Title
  
  J.Biochem. 134
  
  Pages: 19-23
- NAID
  50000881636
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Criystal structure of Mg^<2+>-and Ca^<2+>-bound Gla domain of factor IX complexed with binding protein.2003
- Author(s)
  Shikamoto Y., Morita T., Fujimoto Z., Mizuno H.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 24090-24094
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Characterization and preliminary crystallographic studies of EMS16,an antagonist of collagen receptor (GPIa/IIa) from the venom of Echis multisquamatus.2003
- Author(s)
  Okuda, D., Horii, K., Mizuno, H., Morita, T.
- Journal Title
  
  J.Biochem. 134
  
  Pages: 19-23
- NAID
  50000881636
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Snake Venom Vascular Endothelial Growth Factors VEGFs) Exhibit Potent Activity through Their Specific Recognition of KDR (VEGF Receptor 2).2003
- Author(s)
  Yamazaki Y., Takani K., Atoda H., Morita T.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 51985-51988
- NAID
  10020605339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Crystal Structure of von willebrand factor Al domain complexed with snake venom, Bitiscetin.2003
- Author(s)
  Maita N., Nishio K., Nishimoto E., Matsui T., Shikamoto Y., Morita T., Sadler J.E., Mizuno H.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 37777-37781
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Structural characterization of EMS16,an antagonist of collagen receptor (GPIa/IIa) from the venom of Echis multisquamatus.2003
- Author(s)
  Horii K., Okuda D., Morita T., Mizuno H.
- Journal Title
  
  Biochemistry 42
  
  Pages: 12497-12502
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Crystal structure of trimestatin, a disintegrin containing a cell adhesion recognition motif RGD.2003
- Author(s)
  Fujii Y., Okuda D., Fujimoto Z., Horii K., Morita T., Mizuno, H.
- Journal Title
  
  J.Mol.Biol. 332
  
  Pages: 1115-1122
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Purification and cloning of toxins from elapid venoms that target cyclic nucleotide-gated ion channels.2002
- Author(s)
  Yamazaki Y., Brown R.L., Morita T.
- Journal Title
  
  Biochemistry 41
  
  Pages: 11331-11337
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] A Defect in collagen receptor-Ca^<2+> signaling system in platelets from cattle with Chediak-Higashi syndrome.2002
- Author(s)
  Shiraishi M., Kawashima S., Moroi M., Shin Y., Morita T., Horii Y., Ikeda M., Ito K.
- Journal Title
  
  Thromb.Haemost. 87
  
  Pages: 334-341
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Cloning and characterization of novel snake venom proteins that block smooth muscle contraction.2002
- Author(s)
  Yamazaki Y., Koike H., Sugiyama Y., Motoyoshi K., Wada T., Hishinuma S., Mita M., Morita T.
- Journal Title
  
  Ear.J.Biochem. 269
  
  Pages: 2708-2715
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Prothrombin activation during carbon tetrachloride-induced acute liver injury in mice.2002
- Author(s)
  Mizuguchi H., Yamazaki Y., Shikamoto Y., Shin Y., Sonoda J., Morita T.
- Journal Title
  
  Thrombosis Res. 106
  
  Pages: 257-261
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] A new gene structure of the disintegrin family : A subunit of dimeric disintegrin has short coding region.2002
- Author(s)
  Okuda D., Koike H., Morita T.
- Journal Title
  
  Biochemistry 41
  
  Pages: 14248-14254
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Mutations in the autolytic loop-2 and at Asp^<554> of human prothrombin that enhance protein C activation by meizothrombin.2002
- Author(s)
  Koike H., Okuda D., Morita T.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 15015-15022
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Calcium binding analysis and molecular modeling reveal echis coagulation factor IX/factor X-binding protein has the Ca-binding properties and Ca ion-independent folding of other C- type lectin-like proteins.2002
- Author(s)
  Atoda H., Kaneko H., Mizuno H., Morita T.
- Journal Title
  
  FEBS Lett. 531
  
  Pages: 229-234
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Crystal structure of an anticoagulant protein in complex with the Gla domain of factor X.2001
- Author(s)
  Mizuno H., Fujimoto Z., Atoda H., Morita T.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 98
  
  Pages: 7230-7234
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Crystal structure of bitiscetin, a von Willebrand factor-dependent platelet aggregation inducer.2001
- Author(s)
  Hirotsu S., Mizuno H., Fukuda K., Ma C.Q., Matsui T., Hamako J., Morita T., Titani, K.
- Journal Title
  
  Biochemistry 40
  
  Pages: 13592-13597
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Purification and characterization of a new RGD/KGD-containing dimeric disintegrin, piscivostatin, from the venom of Agkistrodon piscivorus piscivorus : The unique effect of piscivostatin on platelet aggregation.2001
- Author(s)
  Okuda D., Morita T.
- Journal Title
  
  J.Biochem. 130
  
  Pages: 407-415
- NAID
  10007858582
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] The determination of plasma prothrombin level by Ca^<2+>-dependent prothrombin activator (CA-1) during warfarin anticoagulation.2001
- Author(s)
  Iwahashi H., Kimura M., Nakajima N., Yamada D., Morita T.
- Journal Title
  
  J.Heart Valve Dis. 10
  
  Pages: 388-392
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Comparative biochemistry of disintegrins isolated from snake venom : Consideration of the taxonomy and geographical distribution of the snakes in the genus Echis.2001
- Author(s)
  Okuda D., Nozaki C., Sekiya F., Morita T.
- Journal Title
  
  J.Biochem. 129
  
  Pages: 615-620
- NAID
  10007854751
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Journal Article] Snake venom vascular endothelial growth factors (VEGF-Fs) exclusively vary their structures and functions among species.
- Author(s)
  Yamazaki Y, Matsunaga Y, Tokunaga Y, Obayashi S, Saito M and Morita T
- Journal Title
  
  J. Biol. Chem. in press
  
  Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370048
[Patent] カルシウム要求性プロトロンビン活性化酵素1996
- Inventor(s)
  森田隆司
- Industrial Property Rights Holder
  エーザイ株式会社
- Filing Date
  1996-02-29
- Acquisition Date
  2002-06-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13480197
[Presentation] ヘビ毒腺によってつくりだされる血液毒タンパク質の構造と機能2010
- Author(s)
  森田隆司
- Organizer
  第57回トキシンシンポジウム
- Place of Presentation
  長浜ロイヤルホテル
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-19406002
[Presentation] ヘビ毒からの多彩な新規タンパク質の探索2010
- Author(s)
  森田隆司
- Organizer
  屋久島サテライトセミナー
- Place of Presentation
  屋久島いわさきホテル
- Year and Date
  2010-04-25
- Data Source
  KAKENHI-PROJECT-19406002
[Presentation] 新規のKunitz型血液凝固Xa因子インヒビターの単離とその機能2010
- Author(s)
  森田隆司
- Organizer
  第33回日本血栓止血学会学術集会
- Place of Presentation
  鹿児島市城山観光ホテル
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-19406002
[Presentation] 抗凝固薬の現状と将来の展望2010
- Author(s)
  森田隆司
- Organizer
  第4回日本血流血管学会
- Place of Presentation
  順天堂大学本郷キャンパス
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-19406002
[Presentation] Snake venom vascular endothelial growth factors(VEGF-Fs) : Their structural similarities and marked diversities2009
- Author(s)
  Morita T
- Organizer
  4^<th> international conference on exogenous factors affecting thrombosis and haemostasis
- Place of Presentation
  Boston, Massachusetts, USA
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-19406002
[Presentation] Snake venom vascular endothelial growth factors (VEGF-Fs) : Their structural similarities and marked diversities2009
- Author(s)
  Morita, T.
- Organizer
  4^<th> International Conference on exogenous factors affecting thrombosis and haemostasis
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-19406002
[Presentation] 血液凝固IX因子と抗凝固タンパク質(IX/X-bpおよびIX-bp)の相互作用の速度論的解析2008
- Author(s)
  石川みどり、山崎泰男、森田隆司
- Organizer
  日本薬学会128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18370048
[Presentation] 異なるC末端ドメインを持つVEGFキメラの創製とその生物活性2008
- Author(s)
  夘月博和、山崎泰男、森田隆司
- Organizer
  日本薬学会128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19406002
[Presentation] 血液凝固IX因子と抗凝固タンパク質(IX/X-bpおよびIX-bp)の相互作用に対するMg2+の影響2008
- Author(s)
  石川みどり、山崎泰男、森田隆司
- Organizer
  第55回毒素シンポジウム
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-19406002
[Presentation] 血液凝固IX因子と抗凝固タンパク質(IX/X-bpおよびIX-bp)の相互作用の速度論的解析2008
- Author(s)
  石川みどり、山崎泰男、森田隆司
- Organizer
  日本薬学会128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19406002
[Presentation] 組織型および毒型VEGF(血管内皮増殖因子)のゲノム構造解析2008
- Author(s)
  山崎泰男、齋藤麻衣、徳永優子、森田隆司
- Organizer
  第55回毒素シンポジウム
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-18370048
[Presentation] 組織型と毒型の血管内皮増殖因子のゲノム構造解析とその進化論的考察2008
- Author(s)
  齋藤麻衣、徳永優子、長谷川芳裕、山崎泰男、森田隆司
- Organizer
  日本薬学会128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18370048
[Presentation] 異なるC末端ドメインを持つVEGFキメラの創製とその生物活性2008
- Author(s)
  夘月博和、山崎泰男、森田隆司
- Organizer
  日本薬学会128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18370048
[Presentation] 組織型および毒型VEGF(血管内皮増殖因子)のゲノム構造解析2008
- Author(s)
  山崎泰男、齋藤麻衣、徳永優子、森田隆司
- Organizer
  第55回毒素シンポジウム
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-19406002
[Presentation] 組織型と毒型の血管内皮増殖因子のゲノム構造解析とその進化論的考察2008
- Author(s)
  齋藤麻衣、徳永優子、長谷川芳裕、山崎泰男、森田隆司
- Organizer
  日本薬学会128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19406002
[Presentation] 血液凝固IX因子と抗凝固タンパク質(IX/X-bpおよびIX-bp)の相互作用に対するMg^<2+>の影響2008
- Author(s)
  石川みどり、山崎泰男、森田隆司
- Organizer
  第55回毒素シンポジウム
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-18370048
[Presentation] Use of Snake Venom Proteins in Studies of the Structure and Function of Coagulation Factors2007
- Author(s)
  Morita T
- Organizer
  The Ist Seminar on Bioactive Natural Products from Marine Organisms/EndophyticFungi and The JSPS 2nd Medicinal ChemistrySeminar of Asia/Africa Science Platform Program
- Place of Presentation
  Phuket,Thailand
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-18370048
[Presentation] Use of Snake Venom Proteins in StUdies of the Stnlcture and Functionl of Coagulation Factors2007
- Author(s)
  Morita T
- Organizer
  The lst Seminar on Bioactive Natural Products from Marine Organisms/EndophyticFungi and The JSPS 2nd Medicinal ChemistrySeminar of Asia/Africa Science Platform Program
- Place of Presentation
  Phuket,Thailand
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-19406002

1. IWANAGA Sadaaki (90029942)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. YAMAZAKI Yasuo (30308621)

# of Collaborated Projects: 3 results

# of Collaborated Products: 34 results
3. ATODA Hideko (20221046)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. 加藤久雄 (80029959)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 小林紀夫 (60008539)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 松田道生 (50048980)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. KOIKE Hisashi (50328978)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. TORIBE Michihisa (40109856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SAKAKIBARA Shuupei (50072765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAWABATA Shun-ichiro (90183037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 長澤滋治 (70029958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MIZUNO Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
13. 斉坂ゆかり

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MORITA Takashi 森田 隆司

森田 隆司 モリタ タカシ

Research Projects

Research Products

Co-Researchers

Comprehensive study to explore new physiologically active proteins in the snake venoms in the tropical and subtropical regionsPrincipal Investigator

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Studies on the structure and function of new vascular endothelial growth factorsPrincipal Investigator

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Studies on the crystal structure of clotting factors and its binding proteins.Principal Investigator

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Investigation and biochemical study of novel neurotoxins and thrombo-toxin from the venoms of Elapidae and Viperidae snakes.Principal Investigator

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血漿Mgイオンが関与した新しい血液凝固カスケード機構の研究Principal Investigator

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外因系血液凝固開始系の再構成及び開始因子の機能発現の解析Principal Investigator

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血液凝固の分子機構の研究

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血液凝固の分子機構の研究

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血液凝固の分子機構の研究

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ビタミンK依存性凝固因子のGla-domainの機能Principal Investigator

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血管内皮細胞由来の織識因子(トロンボプラスチン)の分子構造Principal Investigator

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リポ多糖感受性セリンプロテアーゼチモーゲンの活性化機構Principal Investigator

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Development and Application of Fluorogenic Peptide Substrates for Determination fo Blood Clotting Proteases

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[Book] Toxins and Hemostasis.2010

MORITA Takashi 森田隆司

森田隆司モリタタカシ