Nakagaki Kazuhide 中垣和英

… Alternative Names

NAKAGAKI Kazuhide 中垣和英

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Researcher Number	90143635
Affiliation (Current)	2025: 東京農工大学, 農学部, 講師 2025: 東京農工大学, 学内共同利用施設等, 客員教授
Affiliation (based on the past Project Information) *help	2012 – 2014: 日本獣医生命科学大学, 獣医学部, 准教授 2007: 日本獣医生命大学, 獣医学部, 准教授 2007: Nippon Veterinary and Life Science University, 獣医学部, associate professor 2006: 日本獣医生命科学大学, 獣医学部, 助教授 2004 – 2005: 日本獣医畜産大学, 獣医学部, 助教授 1999 – 2000: 日本獣医畜産大学, 獣医畜産学部, 講師
Review Section/Research Field	Except Principal Investigator Respiratory organ internal medicine
Keywords	Except Principal Investigator 抗GM-CSF自己抗体 / 肺胞蛋白症 / GM-CSF / Heartworm / Dirofilaria immitis / 自己抗体 / 自己免疫疾患 / autoimmune disease / cytokine / autoantibody … More / bronchoalveolar lavage / lung surfactant / alveolar macrophage / granulocyte macrophage colony stimulating factor / pulmonary alveolar proteinosis / 免疫複合体 / 原発性肺胞蛋白症 / ケモカイン / PDLI / PDL1 / 気管支肺胞洗浄 / 抗サイトカイン自己抗体 / 肺胞タンパク症 / Lymphocyte cen surface antigen / Monoclonal Antibody / autoimmune disease GM-CSF / idiopathic Pulmonary Alveolar Proteinosis / 中和能 / アフィニティー / 顆粒球マクロファージコロニー刺激因子 / リンパ球表面抗原 / モノクローナル抗体 / 特発性肺胞蛋白症 / parasite / Immunodiagnosis / Feline / Cat / 疫学 / heart worm / 寄生虫 / 免疫診断 / ネコ / 犬糸状虫 / 抗体H鎖可変部 / 体細胞超変異 / クラススイッチ / バイオインフォーマティクス / 次世代シークエンス / 肺胞マクロファージ Less

Investigation on mechanism for expansion of GM-CSF autoantibody by next generation sequencing.
- Principal Investigator
  
  NAKATA Koh
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Niigata University
Why does the autoantibody against cytokine incease in patients with idiopathic pulmonary alveolar proteinosis?
- Principal Investigator
  
  NAKATA Koh
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Niigata University
Roles of the autoantibody against GM-CSF in the pathogenesis, diagnosis, and treatment for idiopathic pulmonary alveolar proteinosis
- Principal Investigator
  
  NAKATA Koh
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Niigata University
Research for Immunodiagnoses offeline dirofilariasis
- Principal Investigator
  
  NOGAMI Sadao
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  Nihon University

All 2014 2013 2012 2007

All Journal Article Presentation

[Journal Article] Up-regulation of cluster of differentiation (CD) 11b expression on the surface of canine granulocytes with human granulocyte-macrophage colony-stimulating factor (GM-CSF).2014
- Author(s)
  Nakagaki K, Nunomura Y, Uchida K, Nakata K, Tazawa R.
- Journal Title
  
  J Vet Med Sci
  
  Volume: 76(8) Pages: 1173-6
- NAID
  130004432194
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390208
[Journal Article] Novel aspects on the pathogenesis of Mycoplasma pneumoniae pneumonia and therapeutic implications.2014
- Author(s)
  Saraya T, Kurai D, Nakagaki K, Sasaki Y, Niwa S, Tsukagoshi H, Nunokawa H, Ohkuma K, Tsujimoto N, Hirao S, Wada H, Ishii H, Nakata K, Kimura H, Kozawa K, Takizawa H, Goto H.
- Journal Title
  
  Front Microbiol
  
  Volume: 5 Pages: 410-410
- DOI
  10.3389/fmicb.2014.00410
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390208
[Journal Article] Low concentrations of recombinant granulocyte macrophage-colony stimulating factor derived from Chinese hamster ovary cells augments long-term bioactivity with delayed clearance in vitro2014
- Author(s)
  Hashimoto A, Tanaka T, Itoh Y, Yamagata A, Kitamura N, Tazawa R, Nakagaki K, Nakata K.
- Journal Title
  
  Cytokine
  
  Volume: 68 Issue: 2 Pages: 118-126
- DOI
  10.1016/j.cyto.2014.03.009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-22242001, KAKENHI-PROJECT-24390208, KAKENHI-PROJECT-25461153
[Journal Article] Light chain (κ/λ) ratio of GM-CSF autoantibodies is associated with disease severity in autoimmune pulmonary alveolar proteinosis.2013
- Author(s)
  Nei T, Urano S, Itoh Y, Kitamura N, Hashimoto A, Tanaka T, Motoi N, Kaneko C, Tazawa R, Nakagaki K, Arai T, Inoue Y, Nakata K.
- Journal Title
  
  Clin Immunol
  
  Volume: 149(3) Issue: 3 Pages: 357-364
- DOI
  10.1016/j.clim.2013.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390208, KAKENHI-PROJECT-24406027, KAKENHI-PROJECT-25461153
[Journal Article] Mycoplasma pneumoniae extract induces an IL-17-associated inflammatory reaction in murine lung: Implication for mycoplasmal pneumonia.2013
- Author(s)
  Kurai D, Nakagaki K, Wada H, Saraya T, Kamiya S, Fujioka Y, Nakata K,Takizawa H, Goto H
- Journal Title
  
  Inflammation
  
  Volume: 36(2) Issue: 2 Pages: 285-293
- DOI
  10.1007/s10753-012-9545-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590518, KAKENHI-PROJECT-23591481, KAKENHI-PROJECT-24390208
[Journal Article] IgM-type GM-CSF autoantibody is etiologically a bystander but associated with IgG-type autoantibody production in autoimmune pulmonary alveolar proteinosis.2012
- Author(s)
  Nei T, （10名略）Tazawa R, Nakata K.
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol.
  
  Volume: 302(9) Issue: 9 Pages: 1959-64
- DOI
  10.1152/ajplung.00378.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22242001, KAKENHI-PROJECT-22590852, KAKENHI-PROJECT-23659498, KAKENHI-PROJECT-24390208
[Journal Article] Anti-cytokine autoantibodies are ubiquitous in healthy individuals2007
- Author(s)
  Watanabe, M., Uchida, K., Nakagaki, K., Kanazawa, H., Trapnell, B.C., Hoshino, Y., Kagamu, H., Yoshizawa, H., Keicho, N., Goto, H., Nakata, K
- Journal Title
  
  FEBS Letters 581(10)
  
  Pages: 2017-2021
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390240
[Journal Article] Anti-cytokine autoantibodies are ubiquitous in healthy individuals.2007
- Author(s)
  . Watanabe M, Uchida K, Nakagaki K, Kanazawa H, Trapnell B. C., Hoshino Y, Kagamu H, Yoshizawa H, Keicho N, Goto H, and Nakata K.
- Journal Title
  
  FEBS Letters 581(10)
  
  Pages: 2017-2021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390240
[Journal Article] Anti-cytokine autoantibodies are ubiquitous in healthy individuals.2007
- Author(s)
  Watanabe M, Uchida K, Nakagaki K, Kanazawa H, Trapnell B. C., Hoshino Y, Kagamu H, Yoshizawa H, Keicho N, Goto H, and Nakata K.
- Journal Title
  
  FEBS Letters 581(10)
  
  Pages: 2017-2021
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390240
[Presentation] IgM Type GM-CSF Autoantibody is Etiologically a Bystander but Maybe Involved in Development of IgG Type Autoantibody in Autoimmune Pulmonary Alveolar Proteinosis.2012
- Author(s)
  Nakata K, Nei T, Motoi N, Urano S, Tazawa R, Kanako C, Nakagaki K, Suzuki M, Takizawa J, Azuma A.
- Organizer
  American Thoracic Society Annual Meeting.
- Place of Presentation
  アメリカ
- Year and Date
  2012-05-23
- Data Source
  KAKENHI-PROJECT-24390208
[Presentation] Repertoire Analysis of GM-CSF Autoantibody mRNA by Next Generation Sequencing In Autoimmune Pulmonary Alveolar Proteinosis.2012
- Author(s)
  Nakata K, Nei T, Motoi N, Urano S, Tazawa R, Nakagaki K, Suzuki M, Takizawa J, Azuma A.
- Organizer
  American Thoracic Society Annual Meeting.
- Place of Presentation
  アメリカ
- Year and Date
  2012-05-23
- Data Source
  KAKENHI-PROJECT-24390208

1. NAKATA Koh (80207802)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
2. TAZAWA Ryushi (70301041)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. INOUE Yoshikazu (90240895)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. NEI Takahito (30597670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. TAKIZAWA Jun (70463990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. YOKOSAKI Yasuyuki (80210607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NOGAMI Sadao (90172767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KEICHO Naoto (80332386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 神谷茂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakagaki Kazuhide 中垣 和英

NAKAGAKI Kazuhide 中垣 和英

Research Projects

Research Products

Co-Researchers

Investigation on mechanism for expansion of GM-CSF autoantibody by next generation sequencing.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Why does the autoantibody against cytokine incease in patients with idiopathic pulmonary alveolar proteinosis?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of the autoantibody against GM-CSF in the pathogenesis, diagnosis, and treatment for idiopathic pulmonary alveolar proteinosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research for Immunodiagnoses offeline dirofilariasis

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] Up-regulation of cluster of differentiation (CD) 11b expression on the surface of canine granulocytes with human granulocyte-macrophage colony-stimulating factor (GM-CSF).2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Novel aspects on the pathogenesis of Mycoplasma pneumoniae pneumonia and therapeutic implications.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Low concentrations of recombinant granulocyte macrophage-colony stimulating factor derived from Chinese hamster ovary cells augments long-term bioactivity with delayed clearance in vitro2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Light chain (κ/λ) ratio of GM-CSF autoantibodies is associated with disease severity in autoimmune pulmonary alveolar proteinosis.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mycoplasma pneumoniae extract induces an IL-17-associated inflammatory reaction in murine lung: Implication for mycoplasmal pneumonia.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IgM-type GM-CSF autoantibody is etiologically a bystander but associated with IgG-type autoantibody production in autoimmune pulmonary alveolar proteinosis.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-cytokine autoantibodies are ubiquitous in healthy individuals2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Anti-cytokine autoantibodies are ubiquitous in healthy individuals.2007

Author(s)

Journal Title

Data Source

[Journal Article] Anti-cytokine autoantibodies are ubiquitous in healthy individuals.2007

Author(s)

Journal Title

Description

Data Source

[Presentation] IgM Type GM-CSF Autoantibody is Etiologically a Bystander but Maybe Involved in Development of IgG Type Autoantibody in Autoimmune Pulmonary Alveolar Proteinosis.2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Repertoire Analysis of GM-CSF Autoantibody mRNA by Next Generation Sequencing In Autoimmune Pulmonary Alveolar Proteinosis.2012

Author(s)

Nakagaki Kazuhide 中垣和英

NAKAGAKI Kazuhide 中垣和英