MORIMOTO Junji 森本純司

Researcher Number	90145889
Other IDs
Affiliation (based on the past Project Information) *help	2014: 大阪医科大学, 医学部, 講師 2012 – 2013: 大阪医科大学, 医学部, 准教授 2003 – 2012: 大阪医科大学, 医学部, 講師 1995 – 1997: 大阪医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Laboratory animal science Except Principal Investigator General surgery
Keywords	Principal Investigator 乳癌 / モデル動物 / 癌転移 / 海藻 / 転移抑制物質 / 転移モデル動物 / 海洋生物 / マウス乳癌 / 海洋生物資源 / 抗腫瘍活性 … More Except Principal Investigator 乳癌 / VEGF-C / siRNA / 転移 / リンパ行性転移 / 抗腫瘍効果 / リンパ管新生 / Angiogenesis / Mouse / リンパ節転移 / LYVE-1 / 乳腺外科学 / 血管新生 / マウス / Endostatin / Angiostatin / Mammary carcinoma / Cancer gene therapy / Electrogene transfer / Human umbilical vascular endothelial cell / VEGF-A / Metastasis / リンパ管再生 / リンパ管浸潤 / ヒアルロン酸 / CD44、LYVE-1 / マウス移植乳癌 / CD44 / Vescular endothelial growth factor C(VEGF-C) / リンパ節 / 癌遺伝子治療 / VEGF-D / VEGFR-2 / VEGFR-2受容体デコイ / 遺伝子治療 / SATB1 / VEGFR3 / デコイベクター / リンパ転移 / VEGFR-3デコイ / CEACAM-1 / Microvesicles / 癌治療 / マウス乳癌 / リンパ管リプログラミング / 遺伝子導入 / Prox-1 / VEGFR-3 / Podolanin / リン酸化VEGFR-3 / テネイシンC抗体 / マンゴスチン / 治療 / 抗体医薬 / 複合治療 / テネイシン / α-マンゴスチン / アポトーシス / リンパ管侵襲 / テネイシン抗体 / Mammry carcinoma / Elrctrogene transfer / 血行性転移 / Lymphangiogenesis / Mammary cancer / Lymphatic metastasis / hematogeneous metastasis / Mammary carcioma / mouse Less

Treatment with tenascin C antibody and/or alpha-mangostin reduces tumor growth and lymph node metastasis in a model of metastatic mammary cancer
- Principal Investigator
  
  SHIBATA Masaaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Health Science University
CEACAM-1 promotes lymphangiogenesis and angiogenesis in the inoculated mouse mammary carcinomas.
- Principal Investigator
  
  ITO Yuko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Medical College
Inhibitory study on lymnph node metastasis of mammary cancer by SATB1 and VEGF-C siRNA and decoy vectors
- Principal Investigator
  
  SHIBTA Masa-aki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Health Science University
  Osaka Medical College
Lymphangiogenesis and lymph node-metastasis in the inoculated mouse mammary carcinomas
- Principal Investigator
  
  ITO Yuko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Medical College
Inhibition of lymph node metastasis of mammary cancer due to functional loss of lymphangiogenesis factors by siRNA and/or decoy vectors
- Principal Investigator
  
  SHIBATA Masa-aki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Medical College
Short interfering RNA vectors against VEGF-C and VEGF-A suppress lymphatic metastasis and lymphatic metastasis of mammary cancer model
- Principal Investigator
  
  SHIBATA Masa-aki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Medical College
Combination cancer gene therapy in endostatin and suicide gene for metastatic murine mammary cancers
- Principal Investigator
  
  SHIBATA Masa-aki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka Medical College
Establishment of an animal model for mammary cancer metastasis, and the search for anti-metastatic substancesPrincipal Investigator
- Principal Investigator
  
  MORIMOTO Junji
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Osaka Medical College

All 2014 2013 2012 2011 2010 2008 2007

All Journal Article Presentation Book

[Book] Inhibition of tumor growth and metastasis by a combination of anti-VEGF-C and enhanced IL-12 therapy in an immunocompetent mouse mammary cancer model.「Breast Cancer-Current and Alternative Therapeutic Modalities」2011
- Author(s)
  Shibata, M. A., Morimoto, J., Shibata, E., Harada-Shiba, M. and Fujioka, S.
- Publisher
  InTech社
- Data Source
  KAKENHI-PROJECT-21591682
[Journal Article] Therapy with siRNA for Vegf-c but not for Vegf-d suppresses wide-spectrum organ metastasis in an immunocompetent xenograft model of metastatic mammary cancer2013
- Author(s)
  Shibata MA, Shibata E, Morimoto J and Harada-Shiba M
- Journal Title
  
  Anticancer Res.
  
  Volume: 33 Pages: 4237-4247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591924
[Journal Article] テネイシンC抗体とα-マンゴスチンとの複合投与による乳癌転移抑制の試み2013
- Author(s)
  柴田雅朗、日下部守昭、森本純司、柴田映子、斯波真理子、的場吉信、土佐秀樹、飯沼宗和
- Journal Title
  
  乳癌基礎研究
  
  Volume: 22 Pages: 9-14
- Data Source
  KAKENHI-PROJECT-24591924
[Journal Article] Lymphangiogenesis and Axillary Lymph NodeMetastases Correlated with VEGF-C Expression in Two Immunocompetent MouseMammary CarcinomaModels2012
- Author(s)
  Yuko Ito, Masa-Aki Shibata,Nabil Eid, JunjiMorimoto and Yoshinori Otsuki
- Journal Title
  
  International Journal of Breast Cancer
  
  Volume: 2011 Pages: 1-10
- DOI
  10.4061/2011/867152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591446
[Journal Article] スプライシング・バリアントである可溶性VEGF受容体2型のマウス乳癌リンパ節転移に対する抑制効果2012
- Author(s)
  柴田雅朗、J. Ambati,柴田映子、R. JC Albuquerque,森本純司、斯波真理子、藤岡重和、伊藤裕子、大槻勝紀
- Journal Title
  
  リンパ学
  
  Volume: 35巻 Pages: 23-28
- Data Source
  KAKENHI-PROJECT-22591446
[Journal Article] 新規の内因性可溶性VEGF受容体2型は高転移性マウス乳癌のリンパ節転移を抑制する2011
- Author(s)
  柴田雅朗, Ambati Jayakrishna, 柴田映子, Albuquerque Romulo, 森本純司
- Journal Title
  
  乳癌基礎研究
  
  Volume: 20巻 Pages: 22-30
- Data Source
  KAKENHI-PROJECT-21591682
[Journal Article] VEGF-C, VEGF-DあるいはVEGF-A siRNA発現ベクターを用いた高転移性マウス乳癌モデルに対する癌遺伝子治療2010
- Author(s)
  柴田雅朗, 森本純司, 柴田映子, 大槻勝紀
- Journal Title
  
  リンパ学
  
  Volume: 33巻 Pages: 42-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591682
[Journal Article] The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancer model2010
- Author(s)
  Masa-Aki Shibata, Jayakrishna Ambati, Eiko Shibata, Romulo JC Albuquerque, Junji Morimoto, Yuko Ito, Yoshinori Otsuki
- Journal Title
  
  BMC Medicine
  
  Volume: 8 Pages: 69-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591446
[Journal Article] The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancer model2010
- Author(s)
  Shibata, M. A., Ambati, J., Shibata, E., Albuquerque, R. J., Morimoto, J., Ito, Y. and Otsuki, Y.
- Journal Title
  
  BMC Med
  
  Volume: 8巻
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591682
[Journal Article] The endogenous soluble VEGF receptor-2 isoform suppresses lymph node metastasis in a mouse immunocompetent mammary cancermodel.2010
- Author(s)
  Masa-Aki Shibata, Jayakrishna Ambati, Eiko Shibata, Romulo JC Albuquerque, Junji Morimoto, Yuko Ito,Yoshinori Otsuki
- Journal Title
  
  BMC Medicine
  
  Volume: 8 Pages: 69-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591446
[Journal Article] リンパ管新生(VEGF-C)に対するsiRNAを用いたマウス乳癌転移の抑制ならびにIL-12遺伝子との複合治療2008
- Author(s)
  柴田雅朗、森本純司、赤松香奈子、大槻勝紀
- Journal Title
  
  乳癌基礎研究 17巻
  
  Pages: 49-52
- Data Source
  KAKENHI-PROJECT-19591520
[Journal Article] Combination therapy with short interfering RNA vector against VEGF-C and VEGF-A suppresses lymph node and lung metastasis in a mouse immunocompetent mammary cancer model2008
- Author(s)
  Shibata, M-A., Morimoto, J., Shibata, E. and Otsuki, Y
- Journal Title
  
  Cancer Gene Ther 15
  
  Pages: 776-786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591520
[Presentation] テネイシンＣ抗体またはα-マンゴスチンの単独投与ならびにそれらの複合投与によるマウス乳癌転移抑制2014
- Author(s)
  柴田雅朗, 日下部守昭, 柴田映子, 森本純司, 斯波真理子, 飯沼宗和
- Organizer
  第30回日本毒性病理学会総会・学術集会
- Place of Presentation
  あわぎんホール(徳島)
- Data Source
  KAKENHI-PROJECT-24591924
[Presentation] テネイシンＣ抗体およびα-マンゴスチンによるマウス乳癌の転移抑制2013
- Author(s)
  柴田雅朗, 森本純司, 日下部守昭
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜パシフィコ
- Data Source
  KAKENHI-PROJECT-24591924
[Presentation] テネイシンＣ抗体とα-マンゴスチンとの複合投与による乳癌転移抑制の試み2013
- Author(s)
  柴田雅朗、日下部守昭、森本純司ほか５名
- Organizer
  第118回日本解剖学会総会・全国学術総会
- Place of Presentation
  かがわ国際会議場（高松）
- Data Source
  KAKENHI-PROJECT-24591924
[Presentation] テネイシンＣ抗体とα-マンゴスチンとの複合投与によるマウス乳癌転移抑制の試み2013
- Author(s)
  柴田雅朗, 日下部守昭, 森本純司, 柴田映子, 斯波真理子, 的場吉信, 土佐秀樹, 飯沼宗和
- Organizer
  第22回乳癌基礎研究会
- Place of Presentation
  三重大学医学部
- Data Source
  KAKENHI-PROJECT-24591924
[Presentation] Cell invasion into lymphatics is mediated by hyaluronic acid in CD44-expressing mouse mammary carcinoma2008
- Author(s)
  Yuko Ito, Masa-Aki Shibata, Junji Morimoto, Yoshinori Otsuki
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19591519
[Presentation] Vascularization of lymphatic vessels and VEGF-C expression in mouse metaStatic mammary carcinoma2007
- Author(s)
  Yuko Ito, Masa-Aki Shibata, Junji Morimoto, Yoshinori Otsuki
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19591519
[Presentation] Vascularization of lymphatic vessels and VEGF-C in mouse metastatic mammary carcinoma2007
- Author(s)
  Yuko Ito, Masa-Aki Shibata, Junji Morimoto, Yoshinori Otsuk
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19591519

1. SHIBATA Masa-aki (10319543)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
2. OTSUKI Yoshinori (50140166)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. ITO Yuko (40148432)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. KUSAKABE Moriaki (60153277)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. HIROISHI Shingo (00114190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MORIMOTO Junji 森本 純司

Research Projects

Research Products

Co-Researchers

Treatment with tenascin C antibody and/or alpha-mangostin reduces tumor growth and lymph node metastasis in a model of metastatic mammary cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CEACAM-1 promotes lymphangiogenesis and angiogenesis in the inoculated mouse mammary carcinomas.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Inhibitory study on lymnph node metastasis of mammary cancer by SATB1 and VEGF-C siRNA and decoy vectors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Lymphangiogenesis and lymph node-metastasis in the inoculated mouse mammary carcinomas

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Inhibition of lymph node metastasis of mammary cancer due to functional loss of lymphangiogenesis factors by siRNA and/or decoy vectors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Short interfering RNA vectors against VEGF-C and VEGF-A suppress lymphatic metastasis and lymphatic metastasis of mammary cancer model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Combination cancer gene therapy in endostatin and suicide gene for metastatic murine mammary cancers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of an animal model for mammary cancer metastasis, and the search for anti-metastatic substancesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Inhibition of tumor growth and metastasis by a combination of anti-VEGF-C and enhanced IL-12 therapy in an immunocompetent mouse mammary cancer model.「Breast Cancer-Current and Alternative Therapeutic Modalities」2011

Author(s)

Publisher

Data Source

[Journal Article] Therapy with siRNA for Vegf-c but not for Vegf-d suppresses wide-spectrum organ metastasis in an immunocompetent xenograft model of metastatic mammary cancer2013

Author(s)

Journal Title

Data Source

[Journal Article] テネイシンC抗体とα-マンゴスチンとの複合投与による乳癌転移抑制の試み2013

Author(s)

Journal Title

Data Source

[Journal Article] Lymphangiogenesis and Axillary Lymph NodeMetastases Correlated with VEGF-C Expression in Two Immunocompetent MouseMammary CarcinomaModels2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] スプライシング・バリアントである可溶性VEGF受容体2型のマウス乳癌リンパ節転移に対する抑制効果2012

Author(s)

Journal Title

Data Source

[Journal Article] 新規の内因性可溶性VEGF受容体2型は高転移性マウス乳癌のリンパ節転移を抑制する2011

Author(s)

Journal Title

Data Source

[Journal Article] VEGF-C, VEGF-DあるいはVEGF-A siRNA発現ベクターを用いた高転移性マウス乳癌モデルに対する癌遺伝子治療2010

Author(s)

Journal Title

MORIMOTO Junji 森本純司