FUJIMURA Akio 藤村昭夫

… Alternative Names

藤村昭夫フジムラアキオ

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Researcher Number	90156901
Other IDs
External Links
Affiliation (Current)	2023: 自治医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2022: 自治医科大学, 医学部, 客員教授 2016 – 2018: 自治医科大学, 医学部, 客員教授 2010 – 2016: 自治医科大学, 医学部, 教授 1994 – 2007: Jich Medical School,, 医学部, 教授 1993: 自治医科大学, 医学部, 助教授 1988: Department of Clinical pharmacology, Medical College of Oita, 医学部, 助手 1986: 大分医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Applied pharmacology / 応用薬理学・医療系薬学 / General surgery / Internal medicine of the bio-information integration and related fields / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator 応用薬理学・医療系薬学 / General surgery / Kidney internal medicine / Kidney internal medicine
Keywords	Principal Investigator 臨床薬理学 / QT延長 / 心房性ナトリウム利尿ペプチド / シノルファン / シクロスポリン / sinorphan / 腎障害 / 応用薬理学 / 有害反応 / 薬理学 … More / 白血病 / 循環器 / 薬物有害反応 / アミカシン / 腎機能障害 / ANP / cyclosporin / amikacin / nephrotoxicity / 分解酵素阻害薬 / 腎機能保護 / 免疫抑制薬 / atrial natriuretic peptide / enkephalinase inhibitor / cyclosporine / renal protection / 大腸菌O-157 / ベロ毒素 / リポ多糖 / 臓器障害 / 好中球 / O-157 / 抗好中球抗体 / IL6 / 時間薬理 / E-coli O157 / verotoxin / lipopoly saccharide / renal damage / neutrophil / 慢性腎不全 / 血液浄化法 / OAT-3 / インドキシル硫酸 / 尿毒症性物質 / 動脈硬化 / 尿素症性物質 / 血管平滑筋 / 有機アニオン輸送体 / ABCA8 / chronic renal failure / blood purification / organic anion transporter-3 / indoxylsulfate / uremic toxin / arteriosclerosis / 薬剤反応性 / 体内時計 / 血液脳関門 / 薬物動態 / 高齢者 … More Except Principal Investigator ジゴキシン / シクロスポリン / anion exchanger / 慢性腎不全 / バイオ人工臓器 / 尿毒症性物質 / 有機アニオン輸送体 / ハイブリッド型人工腎臓 / ジゴキシン中毒 / 血液浄化法 / 多剤耐性蛋白 / ハイブリット型腎臓 / 血清浄化法 / ホロファイバー型モジュール / ドキソルビシン / 薬物中毒 / ホロファイバーモジュール / Hybrid-kidney / digoxin intoxication / hemoperfusion / Multidrug reisistance protein / 遺伝子治療 / 遺伝子銃 / 局所治療 / 固形癌治療 / gene therapy / Gene Gun / local therapy / solid tumor therapy / Caco2細胞 / P-糖蛋白質 / チトクロームP-450 3A4 / 薬物相互作用 / フェノバルビタール / リファンピシン / チトクロムP-450 3A4 / Caco2 / プロブコール / Caco-2 cell / P-glycoprotein / cytochrome P-450 3A4 / drug interaction / phenobarbital / rifampicin / digoxin / 5-FU / 尿中ウラシル / 尿中ジヒドロウラシル / 薬物動態 / 適正使用 / ジヒドロピリミジンデヒドロゲナーゼ / 5-fluorouracil / urinary uracil / urinary dihydrouracil / pharmacokinetics / reference range / dihydropyrimidine dehydrogenase / 集合管 / hensin / 代謝性アシドーシス / 薬物有害反応 / 重炭酸 / collecting duct / Hensin / metabolic acidosis / cyclosporine A / Drug adverse reactions / 高血圧症 / 時間薬理学 / 血圧日内リズム / atenolol / 24時間血圧測定 / 血圧日内変動 / β遮断薬 / hypertension / chronopharmacology / circadian rhythm of blood pressure Less

Prediction of drug disposition into brain in elders using clusters of daily variation in gene expressionPrincipal Investigator
- Principal Investigator
  
  藤村昭夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Jichi Medical University
Development of safety prediction biomarker for drug eluting coronary stent therapyPrincipal Investigator
- Principal Investigator
  
  FUJIMURA Akio
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Internal medicine of the bio-information integration and related fields
- Research Institution
  Jichi Medical University
Basic and clinical research aimed at elucidation of the pathological mechanism of aortic dissection and development of therapeutic methodsPrincipal Investigator
- Principal Investigator
  
  FUJIMURA Akio
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Jichi Medical University
Development of a method to attenuate the adverse effect of anti-arrhythmic bepridilPrincipal Investigator
- Principal Investigator
  
  Fujimura Akio
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Jichi Medical University
Development of the method for reducing the adverse effect of arsenic trioxidePrincipal Investigator
- Principal Investigator
  
  FUJIMURA Akio
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Jichi Medical University
Development of hybrid kidney for removal of protein-bound anionic uremic toxins
- Principal Investigator
  
  TSURUOKA Shuichi
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Tsukuba
Development of bio-artificial kidneyPrincipal Investigator
- Principal Investigator
  
  FUJIMURA Akio
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  JICHI MEDICAL UNIVERSITY
Regulation of acid secretion in cortical collecting duct : An Effect Mediated by Hensin.
- Principal Investigator
  
  TSURUOKA Shuichi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Jichi Medical School
Study on Escherichia coli O-157-induced renal damagePrincipal Investigator
- Principal Investigator
  
  FUJIMURA Akio
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Jichi Medical University
Development of hybrid-kidney for drug intoxication and its clinical application
- Principal Investigator
  
  TSURUOKA Shuchi
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Jichi Medical School
Cancer Gene Therapy with a Hand-Held Gene Gun
- Principal Investigator
  
  KOBAYASHI Eiji
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Jichi Medical School
PREDICTION OF DRUG INTERACTION IN VITRO -FOCUSING ON CYTOCHROME P-450 3A AND P-GLYCOPROTEIN-
- Principal Investigator
  
  SUGIMOTO Koichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  JICHI MEDICAL SCHOOL
Possible prediction to fluorouracil (5-FU) anti-cancer agent -Studies of urinary pyrimidine levels in the cancer patients and 5-FU pharmacokinetics in the patients with cancer.
- Principal Investigator
  
  TOKUE Akihiko, 原田和博
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Jichi Medical School
Renal protective effect of sinorphan, an enkephalinase inhibitorPrincipal Investigator
- Principal Investigator
  
  FUJIMURA Akio.MD.PhD.
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Jichi Medical School
Preventive effect of an enkephalinase inhibitor on drug-induced nephrotoxicity.Principal Investigator
- Principal Investigator
  
  FUJIMURA Akio
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Jichi Medical School
Chronopharmacology of antihypertensive drugs.
- Principal Investigator
  
  EBIHARA Akio
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Medical College of Oita

All 2016 2015 2013 2011 2010 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation

[Journal Article] Influence of genetic polymorphisms of multidrug and toxin extrusion protein 1 on its mRNA expression in peripheral blood cells.2016
- Author(s)
  Ando H, Nakano K, Ushijima K, Kurokawa S, Washino S, Hosohata K, Morita T, Fujimura A.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: in press
- DOI
  10.1016/j.jphs.2016.03.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460658, KAKENHI-PROJECT-26460631
[Journal Article] Early urinary biomarkers for renal tubular damage in spontaneously hypertensive rats on a high-salt intake.2016
- Author(s)
  Hosohata K, Yoshioka D, Tanaka A, Ando H, Fujimura A.
- Journal Title
  
  Hypertens Res.
  
  Volume: 39 Pages: 19-26
- DOI
  10.1038/hr.2015.103
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460658, KAKENHI-PROJECT-26460631
[Journal Article] Lipopolysaccharide-induced inflammation or unilateral ureteral obstruction yielded multiple types of glycosylated Lipocalin 22016
- Author(s)
  Fujiwara Y, Tsuchiya H, Sakai N, Shibata K, Fujimura A, Koshimizu TA.
- Journal Title
  
  Journal of Inflammation
  
  Volume: 13 Pages: 7-7
- DOI
  10.1186/s12950-016-0116-5
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460658, KAKENHI-PROJECT-26860173
[Journal Article] Association of decreased mRNA expression of multidrug and toxin extrusion protein 1 in peripheral blood cells with the development of flutamide-induced liver injury2015
- Author(s)
  Nakano K, Ando H, Kurokawa S, Hosohata K, Ushijima K, Takada M, Tateishi M, Yonezawa A, Masuda S, Matsubara K, Inui KI, Morita T, Fujimura A.
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: ｉｎ　ｐｒｅｓｓ Pages: 1191-1197
- DOI
  10.1007/s00280-015-2743-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460631, KAKENHI-PROJECT-25460658, KAKENHI-PROJECT-15H04666
[Journal Article] Influence of dioxin on the daily variation of insulin sensitivity in mice.2015
- Author(s)
  Takuma M, Ushijima K, Kumazaki M, Ando H, Fujimura A.
- Journal Title
  
  Environ Toxicol Pharmacol
  
  Volume: 40 Pages: 349-351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460658
[Journal Article] α-Lipoic acid protects against arsenic trioxide-induced acute QT prolongation in anesthetized guinea pigs2013
- Author(s)
  Kumazaki M, Ando H, Kakei M, Ushi j ima K, Taniguchi Y, Yoshida M, Yamato S, Washino S, Koshimizu TA, Fujimura A
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 705 Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590504
[Journal Article] Protective Effect of .ALPHA.-Lipoic Acid Against Arsenic Trioxide-Induced Acute Cardiac Toxicity in Rats2011
- Author(s)
  Kumazaki M, Ando H, Sasaki A, Koshimizu TA, Ushijima K, Hosohata K, Oshima Y, Fujimura A
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 115 Issue: 2 Pages: 244-248
- DOI
  10.1254/jphs.10280sc
  10.1254/jphs.10280SC
- NAID
  10029892273
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590504
[Journal Article] Statins inhibited erythropoietininduced proliferation of rat vascular smooth muscle cells.2010
- Author(s)
  Kaneda T, Tsuruoka S, Fujimura A.
- Journal Title
  
  Eur J Pharmacol. 649
  
  Pages: 38-43
- NAID
  120007137842
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590961
[Journal Article] Hypertension Induced by Erythropoietin Has a Correlation With Truncated Erythropoietin Receptor mRNA in Endothelial Progenitor Cells of Hemodialysis Patients2009
- Author(s)
  Ioka T, Tsuruoka S, Ito C, Iwaguro H, Asahara T, Fujimura F, Kusano E.
- Journal Title
  
  Clin Pharmacol Ther. 86(2)
  
  Pages: 154-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590961
[Journal Article] Basolateral Na(+)/H(+) exchange maintains potassium secretion during diminished sodium transport in the rabbit cortical collecting duct2009
- Author(s)
  Muto S, Tsuruoka S, Miyata Y, Fujimura A, Kusano E, Wang W, Seldin D, Giebisch G.
- Journal Title
  
  Kidney Int. 75 (1)
  
  Pages: 25-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590961
[Journal Article] Mechanism of Cd-induced inhibition of Na-glucose cotransporter in rabbit proximal tubule cells : Roles of luminal pH and membrane-bound carbonic anhydrase.2008
- Author(s)
  Tsuruoka S, Swenson ER, Fujimura A, Imai M.
- Journal Title
  
  Nephron Physiol. 110(2)
  
  Pages: 11-20
- NAID
  120007138513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590961
[Journal Article] Mechanism of Cd-induced inhibition of Na-glucose cotransporter in rabbit proximal tubule cells: Roles of luminal pH and membrane-bound carbonic anhydrase.2008
- Author(s)
  Tsuruoka S, Swenson ER, Fujimura A, Imai M.
- Journal Title
  
  Nephron Physiol. 110 (2)
  
  Pages: 11-20
- NAID
  120007138513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590961
[Journal Article] Mechanism of Cd-induced inhibition of Na-glucose cotransporter in rabbit proximal tubule cells : Roles of luminal pH and membrane-bound carbonic anhydrase2008
- Author(s)
  Tsuruoka S, Swenson ER, Fujimura A, Imai M.
- Journal Title
  
  Nephron Physiol 110 (2)
  
  Pages: 11-20
- NAID
  120007138513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590961
[Journal Article] TRPV4 as a flow sensor in the flow-dependent K+ secretion from the cortical collecting duct.2007
- Author(s)
  Taniguchi J, Tsuruoka S, Mizuno A, Sato JI, Fujimura A, Suzuki M.
- Journal Title
  
  Am J Physiol Renal Physiol (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Dosing time-dependent variation of bone resorption by cyclosporin A in rats' femurs.2007
- Author(s)
  Tsuruoka S, Kaneda T, Maeda A, Ioka T, Fujimura A.
- Journal Title
  
  Eur J Pharmacol 564
  
  Pages: 226-231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590961
[Journal Article] TRPV4 as a flow sensor in flow-dependent K+ secretion from the cortical collecting duct.2007
- Author(s)
  Taniguchi J, Tsuruoka S, Mizuno A, Sato J, Fujimura A, Suzuki M.
- Journal Title
  
  Am J Physiol Renal Physiol 292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590961
[Journal Article] TRPV4 as a flow sensor in the flow-dependent K+ secretion from the cortical collecting duct.2007
- Author(s)
  Taniguchi J, Tsuruoka S, Fujimura A, et al.
- Journal Title
  
  Am J Physiol Renal Physiol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] TRPV4 as a flow sensor in the flow-dependent K+ secretion from the cortical collecting duct.2007
- Author(s)
  Taniguchi J, Fujimura A(5番目).
- Journal Title
  
  Am J Physiol Renal Physiol (In press)
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Changes of neutrophil function during the inter-dialytic period.2006
- Author(s)
  Kitoh Y, Tsuruoka S, Fujimura A, et al.
- Journal Title
  
  Clin Nephrol 65(1)
  
  Pages: 75-77
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Changes of neutrophil function during the inter-dialytic period.2006
- Author(s)
  Kitoh Y, Fujimura A(6番目).
- Journal Title
  
  Clin Nephrol. 65(1)
  
  Pages: 75-77
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Defect in Parathyroid Hormone-Induced Luminal Calcium Absorption in Connecting Tubules of Klotho Mice.2006
- Author(s)
  Tsuruoka S, Fujimura A et al.
- Journal Title
  
  Nephrol Dial Tranplant 21(10)
  
  Pages: 2762-2767
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Indoxyl sulfate stimulates proliferation of rat vascular smooth muscle cells.2006
- Author(s)
  Yamamoto H, Tsuruoka S, Ioka T, Ando H, Ito C, Akimoto T, Fujimura A, Asano Y, Kusano E.
- Journal Title
  
  Kidney Int 69(10)
  
  Pages: 1780-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Defect in Parathyroid Hormone-Induced Luminal Calcium Absorption in Connecting Tubules of Klotho Mice.2006
- Author(s)
  Tsuruoka S, Fujimura A(8番目).
- Journal Title
  
  Nephrol Dial Tranplant. 21(10)
  
  Pages: 2762-2767
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Defect in Parathyroid Hormone-Induced Luminal Calcium Absorption in Connecting Tubules of Klotho Mice.2006
- Author(s)
  Tsuruoka S, Nishiki K, Ioka T, Ando H, Saito Y, Kurabayashi M, Nagai R, Fujimura A.
- Journal Title
  
  Nephrol Dial Tranplant 21(10)
  
  Pages: 2762-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Indoxyl sulfate stimulates proliferation of rat vascular smooth muscle cells.2006
- Author(s)
  Yamamoto H, Fujimura A et al.(7番目)
- Journal Title
  
  Kidney Int (In press)
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Indoxyl sulfate stimulates proliferation of rat vascular smooth muscle cells.2006
- Author(s)
  Yamamoto H, Fujimura, A(7番目).
- Journal Title
  
  Kidney Int. 69(10)
  
  Pages: 1780-1785
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Endothelin and Nitric Oxide Mediate the Adaptation of the Cortical Collecting Duct to Metabolic Acidosis.2006
- Author(s)
  Tsuruoka S, Watanabe S, Purkerson JM, Fujimura A, Schwartz GJ.
- Journal Title
  
  Am J Physiol Renal Physiol 291(4)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Endothelin and Nitric Oxide Mediate the Adaptation of the Cortical Collecting Duct to Metabolic Acidosis.2006
- Author(s)
  Tsuruoka S, Fujimura A(4番目).
- Journal Title
  
  Am J Physiol Renal Physiol. 291(4)
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Changes of neutrophil function during the inter-dialytic period.2006
- Author(s)
  Kitoh Y, Tsuruoka S, Ohmori M, Sugimoto K, Saitoh T, Fujimura A.
- Journal Title
  
  Clin Nephrol 65(1)
  
  Pages: 75-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Indoxyl sulfate stimulates proliferation of rat vascular smooth muscle cells.2006
- Author(s)
  Yamamoto H, Tsuruoka S, Fujimura A, et al.
- Journal Title
  
  Kidney Int 69(10)
  
  Pages: 1780-1785
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Endothelin and Nitric Oxide Mediate the Adaptation of the Cortical Collecting Duct to Metabolic Acidosis.2006
- Author(s)
  Tsuruoka S, Fujimura A, et al.
- Journal Title
  
  Am J Physiol Renal Physiol 291(4)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Citrate reverses Cyclosporin A-induced metabolic acidosis and bone resorption in rat.2005
- Author(s)
  Tsuruoka S, Schwartz GJ, Ioka T, Yamamoto H, Ando H, Fujimura A.
- Journal Title
  
  Am J Nephrol 25(3)
  
  Pages: 233-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Citrate reverses Cyclosporin A-induced metabolic acidosis and bone resorption in rat.2005
- Author(s)
  Tsuruoka S, Fujimura A et al.(6番目)
- Journal Title
  
  Am J Nephrol 25(3)
  
  Pages: 233-239
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] The bioreactor with CYP34A- and glutamine synthetase-introduced HepG2 cells : Treatment of hepatic failure dog with diazepam overdosage2005
- Author(s)
  Wang N, Fujimura A et al.(9番目)
- Journal Title
  
  Artif Org 29
  
  Pages: 681-684
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] The bioreactor with CYP3A4- and glutamine synthetase-introduced H epG2 cells : Treatment of hepatic failure dog with diazepam overdosage.2005
- Author(s)
  Wang N, Tsuruoka S, Fujimura A, et al.
- Journal Title
  
  Artif Org 29(8)
  
  Pages: 681-684
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Cyclosporin produces distal Renal Tubular Acidosis by blocking peptidyl cis-trans prolyl isomerase activity of cyclophilin.2005
- Author(s)
  Watanabe S, Fujimura A et al.(6番目)
- Journal Title
  
  Am J Physiol Renal Physiol 288(1)
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Effect of trimethoprim-sulfamethoxazole on Na+ and K+ transport in the rabbit cortical collecting duct.2005
- Author(s)
  Muto S, Tsuruoka S, Fujimura A, et al.
- Journal Title
  
  Nephron Physiol 102(3-4)
  
  Pages: 51-60
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Cyclosporin produces distal Renal Tubular Acidosis by blocking peptidyl cis-trans prolyl isomerase activity of cyclophilin.2005
- Author(s)
  Watanabe S, Tsuruoka S, Vijayakumar S, Fischer G, Zhang Y, Fujimura A, Al-Awqati Q, Schwartz GJ.
- Journal Title
  
  Am J Physiol Renal Physiol 288(1)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Citrate reverses Cyclosporin A-induced metabolic acidosis and bone resorption in rat.2005
- Author(s)
  Tsuruoka S, Fujimura A. et al.
- Journal Title
  
  Am J Nephrol 25(3)
  
  Pages: 233-239
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Cyclosporin produces distal Renal Tubular Acidosis by blocking peptidyl cis-trans prolyl isomerase activity of cyclophilin.2005
- Author(s)
  Watanabe S, Fujimura A (6番目) et al.
- Journal Title
  
  Am J Physiol Renal Physiol 288
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Effect of trimethoprim-sulfamethoxazole on Na+ and K+ transport in the rabbit cortical collecting duct.2005
- Author(s)
  Muto S, Fujimura A et al.(9番目)
- Journal Title
  
  Nephron Physiol 102(3-4)
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Effect of trimethoprim-sulfamethoxazole on Na+ and K+ transport in the rabbit cortical collecting duct.2005
- Author(s)
  Muto S, Tsuruoka S, Miyata Y, Fujimura A, Asano Y, Kusano E.
- Journal Title
  
  Nephron Physiol 102(3-4)
  
  Pages: 51-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] The bioreactor with CYP3A4- and glutamine synthetase-introduced H epG2 cells : Treatment of hepatic failure dog with diazepam overdosage.2005
- Author(s)
  Wang N, Tsuruoka S, Yamamoto H, Enosawa S, Omasa T, Sata N, Matsumura T, Nagai H, Fujimura A.
- Journal Title
  
  Artif Org 29(8)
  
  Pages: 681-4
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Treatment of digoxin intoxication model by hybrid kidney with hollowfiber module for clinical hemodialysis.2004
- Author(s)
  Tsuruoka S, Fujimura A (8番目) et al.
- Journal Title
  
  Nephrol Dial Transplant 19
  
  Pages: 1339-40
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Treatment of digoxin intoxication model by hybrid kidney with hollowfiber module for clinical hemodialysis.2004
- Author(s)
  Tsuruoka S, Nishiki K, Wakaumi M, Wang N, Yamamoto H, Ando H, Imai M, Fujimura A.
- Journal Title
  
  Nephrol Dial Transplant 19(5)
  
  Pages: 1339-1340
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571032
[Journal Article] Adsorption of oxacalcitriol by polysulfone haemodialyzer in patients with secondary hyperparathyroidism.2004
- Author(s)
  Tsuruoka S, Fujimura A (6番目) et al.
- Journal Title
  
  Br J Clin Pharmacol 58
  
  Pages: 488-495
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] β2-microglobulin adsorption column reduces digoxin trough level during hemodialysis : 3 case reports.2004
- Author(s)
  Tsuruoka S, Fujimura A (7番目) et al.
- Journal Title
  
  Ther.Drug Monit 26
  
  Pages: 450-452
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] β2-microglobulin adsorption column reduces digoxin trough level during hemodialysis : 3 case reports.2004
- Author(s)
  Tsuruoka S, Wakaumi M, Yamamoto H, Ando H, Saito A, Fujimura A.
- Journal Title
  
  Ther Drug Monit 26(4)
  
  Pages: 450-2
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Treatment of digoxin intoxication model by hybrid kidney with hollowfiber module for clinical hemodialysis.2004
- Author(s)
  Tsuruoka S, Nishiki K, Wakaumi M, Wang N, Yamamoto H, Ando H, Imai M, Fujimura A.
- Journal Title
  
  Nephrol Dial Transplant 19(5)
  
  Pages: 1339-40
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Adsorption of oxacalcitriol by polysulfone hemodialyzer in patients with secondary hyperparathyroidism.2004
- Author(s)
  Tsuruoka S, Yamamoto H, Wakaumi M, Ando H, Saito T, Fujimura A.
- Journal Title
  
  Br J Clin Pharmacol 58(5)
  
  Pages: 488-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Chronopharmacology of oxacalcitriol in 5/6 nephrectomized rats.2004
- Author(s)
  Tsuruoka S, Nishiki K, Wakaumi M, Yamamoto H, Ando H, Wang N, Fujimura A.
- Journal Title
  
  Life Sci. 75
  
  Pages: 809-822
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571032
[Journal Article] Treatment of digoxin intoxication model by hybrid kidney with hollowfiber module for clinical hemodialysis.2004
- Author(s)
  Tsuruoka S, Fujimura A. et al.
- Journal Title
  
  Nephrol Dial Transplant 19(5)
  
  Pages: 1339-1340
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] β2-microglobulin adsorption column reduces digoxin trough level during hemodialysis : 3 case reports.2004
- Author(s)
  Tsuruoka S, Fujimura A, et al.
- Journal Title
  
  Ther Drug Monit 26(4)
  
  Pages: 450-452
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Adsorption of oxacalcitriol by polysulfone hemodialyzer in patients with secondary hyperparathyroidism.2004
- Author(s)
  Tsuruoka S, Fujimura A, et al.
- Journal Title
  
  Or J Clin Pharmacol 58(5)
  
  Pages: 488-495
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591270
[Journal Article] Inhibition of Rho-kinase reduces Na-H exchanger activity and natriuresis in rat.2003
- Author(s)
  Nishiki, K., Tsuruoka, S., Kawaguchi, A., Sugimoto, K., Imai, M., Fujimura A.
- Journal Title
  
  J Pharmacol Exp Ther. 304
  
  Pages: 723-728
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571032
[Journal Article] Nitric oxide production modulates cyclosporine A-induced distal renal tubular acidosis in the rat.2003
- Author(s)
  Tsuruoka, S., Schwartz GJ, Wakaumi, M., Nishiki, K., Yamamoto H, Purkerson JM, Fujimura, A.
- Journal Title
  
  J Pharmacol Exp Ther. 305
  
  Pages: 840-845
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571032
[Presentation] トキシコゲノミクス研究による毒性発現機序の解明とその対処法の探索2010
- Author(s)
  藤村昭夫
- Organizer
  第31回日本臨床薬理学会年会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-22590504
[Presentation] Dosing Time-Dependent Variation of Bone Resorption by Cyclosporin A in Rats Femurs2009
- Author(s)
  Tsuruoka S, Kaneko S, Yamagata K, Fujimura A.
- Organizer
  American Society of Nephrology's 42nd Annual Renal Week
- Place of Presentation
  San Diego CA, USA
- Data Source
  KAKENHI-PROJECT-19590961
[Presentation] Dosing Time-Dependent Variation of Bone Resorption by Cyclosporin A in Rats Femurs.2009
- Author(s)
  Tsuruoka S, Kaneko S, Yamagata K, Fujimura A
- Organizer
  American Society of Nephrology's 42nd Annual Renal Week
- Place of Presentation
  San Diego CA, USA
- Data Source
  KAKENHI-PROJECT-19590961
[Presentation] スタチンはエリスロポエチンによる培養血管平滑筋細胞増殖を抑制する2008
- Author(s)
  金田多絵、鶴岡秀一、藤村昭夫
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590961
[Presentation] Statin suppresses erythropoietin (EPO)-induced proliferation of vascular smooth muscle cells in vitro2008
- Author(s)
  Kaneda A, Tsuruoka S, Fujimura A.
- Organizer
  American Society of Nephrology's 41st Annual Renal Week
- Place of Presentation
  Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-19590961
[Presentation] Statin suppresses erythropoietin (EPO)-induced proliferation of vascular smooth muscle cells in vitro.2008
- Author(s)
  Kaneda A, Tsurupka S, Fujimura A.,
- Organizer
  American Society of Nephrology's 41st Annual Renal Week,
- Place of Presentation
  Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-19590961
[Presentation] Statin suppresses erythropoietin (EPO)-induced proliferation of vascular smooth muscle cells in vitro.2008
- Author(s)
  Kaneda A, Tsuruoka S, Fujimura A
- Organizer
  American Society of Nephrology's 41st Annual Renal Week
- Place of Presentation
  Philadelphia, PA, USA
- Data Source
  KAKENHI-PROJECT-19590961
[Presentation] Mechanism of cadmium(Cd)-induced Na-glucose cotransporter inhibition in isolated perfused rabbit proximal tubule cells : Roles of luminal pH and luminal membrane-bound carbonic anhydrase (CA).2007
- Author(s)
  Tsuruoka S, Swenson ER, Fujimura A, Imai M.
- Organizer
  American Society of Nephrology's 40th Annual Renal Week
- Place of Presentation
  San Francisco CA, USA
- Data Source
  KAKENHI-PROJECT-19590961

1. TSURUOKA Shuichi (50285798)

# of Collaborated Projects: 6 results

# of Collaborated Products: 47 results
2. SUGIMOTO Kohichi (90244491)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KOSHIMIZU Takaaki (20392491)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. HARADA Kazuhiro.MD.PhD. (70245059)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KOBAYASHI Eiji (00245044)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TOKUE Akihiko (80049022)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 相澤健一 (70436484)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KUMASAKI Msafumi (50547966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ANDO Hitoshi (50382875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. KAKEI Masafumi (90214270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SHIGA Tsuyoshi (00277211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MIYAMORI Isamu.MD.PhD. (40142278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MIURA Sadayasu.MD.PhD. (60048965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. ASANO Yasushi (00050500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MUTO Shigeaki (40190855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. HAKAMATA Yoji (00218380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MURAKAMI Takashi (00326852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. YOSHIDA Shigeto (10296121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. HOSOYA Yoshinori (30275698)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KAWAHARA Yoshikazu (20195126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. EBIHARA Akio (10048960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KOIKE Yuichi (90109421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 鈴木誠 (10196868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. 藤田大司 (20741200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 今井靖 (20359631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 牛島健太郎 (70448843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 土屋裕義 (80508755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 細畑圭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
29. 増田智先

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 藤原葉子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUJIMURA Akio 藤村 昭夫

藤村 昭夫 フジムラ アキオ

Research Projects

Research Products

Co-Researchers

Prediction of drug disposition into brain in elders using clusters of daily variation in gene expressionPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Development of safety prediction biomarker for drug eluting coronary stent therapyPrincipal Investigator

Principal Investigator

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Research Institution

Basic and clinical research aimed at elucidation of the pathological mechanism of aortic dissection and development of therapeutic methodsPrincipal Investigator

Principal Investigator

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Research Institution

Development of a method to attenuate the adverse effect of anti-arrhythmic bepridilPrincipal Investigator

Principal Investigator

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Research Institution

Development of the method for reducing the adverse effect of arsenic trioxidePrincipal Investigator

Principal Investigator

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Research Institution

Development of hybrid kidney for removal of protein-bound anionic uremic toxins

Principal Investigator

Project Period (FY)

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Research Institution

Development of bio-artificial kidneyPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Regulation of acid secretion in cortical collecting duct : An Effect Mediated by Hensin.

Principal Investigator

Project Period (FY)

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Research Institution

Study on Escherichia coli O-157-induced renal damagePrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Development of hybrid-kidney for drug intoxication and its clinical application

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Cancer Gene Therapy with a Hand-Held Gene Gun

Principal Investigator

Project Period (FY)

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Research Institution

PREDICTION OF DRUG INTERACTION IN VITRO -FOCUSING ON CYTOCHROME P-450 3A AND P-GLYCOPROTEIN-

Principal Investigator

Project Period (FY)

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Research Institution

Possible prediction to fluorouracil (5-FU) anti-cancer agent -Studies of urinary pyrimidine levels in the cancer patients and 5-FU pharmacokinetics in the patients with cancer.

Principal Investigator

Project Period (FY)

FUJIMURA Akio 藤村昭夫

藤村昭夫フジムラアキオ