KATO Yoshihisa 加藤善久

… Alternative Names

Researcher Number	90161132
Other IDs
External Links
Affiliation (Current)	2022: 徳島文理大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2020: 徳島文理大学, 薬学部, 教授 2010 – 2016: Tokushima Bunri University, 薬学部, 教授 2009 – 2010: Tokushima Bunri University, 香川薬学部, 教授 2007 – 2009: Tokushima Bunri University, Kagawa School of Pharmaceutical Sciences, Associate Professor 2006: 徳島文理大学, 香川薬学部, 助教授 1997 – 2005: 静岡県立大学, 薬学部, 講師 1999: School of Pharmaceutical Sciences, University of Shizuoka Assistant Professor, 医学部, 講師
Review Section/Research Field	Principal Investigator Risk sciences of radiation/Chemicals / 環境影響評価(含放射線生物学) / Risk sciences of radiation and chemicals / Basic Section 63030:Chemical substance influence on environment-related Except Principal Investigator Risk sciences of radiation/Chemicals / Medical pharmacy
Keywords	Principal Investigator PCB / UDP-glucuronosyltransferase / サイロキシン / ラット / 肝臓 / マウス / 甲状腺ホルモン撹乱 / トランスサイレチン / Kanechlor-500 / グルクロン酸抱合酵素 … More Except Principal Investigator 臭素化合物 / 海綿 / 抗菌活性 / リード化合物 / 創薬 / カテコール / LC / MS / 海綿動物 / ハロゲン化合物 / 母乳 / ヒドロキシ臭素化ジフェニルエーテル / 高速液体クロマトグラフ / DDS / 薬物治療 / リポソーム / 癌化学療法 / 耐性癌 / 代謝 / 環境動態 / ヒト / 血清 / 海藻 / クジラ / 抗酸化活性 / 内分泌かく乱性 Less

PCBなどの化学物質の甲状腺ホルモン濃度低下作用発現メカニズムの全容解明Principal Investigator
- Principal Investigator
  
  加藤善久
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  Tokushima Bunri University
Study on the possible mechanism for the polychlorinated biphenyl-induced liver-selective accumulation of thyroxinePrincipal Investigator
- Principal Investigator
  
  Kato Yoshihisa
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Tokushima Bunri University
Metabolic activation of naturally porduced halogenated compounds in human
- Principal Investigator
  
  KOICHI Haraguchi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
Study on the exact mechanism for the polychlorinated biphenyl-induced decrease in the serum thyroxine levelPrincipal Investigator
- Principal Investigator
  
  KATO Yoshihisa
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tokushima Bunri University
A novel mechanism for polychlorinated biphenyl-induced decrease in serum thyroxine levelPrincipal Investigator
- Principal Investigator
  
  YOSHIHISA Kato
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tokushima Bunri University
Research of antibacterial chemicals in marine sponge and development of lead compounds for therapy in infectious diseases
- Principal Investigator
  
  HARAGUCHI Koichi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
Development of liposome for treatment of multidrug-resistant cancer
- Principal Investigator
  
  ATOBE Kazutaka
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokushima Bunri University
A possible mechanism for decrease in serum thyroxine level by polychlorinated biphenylsPrincipal Investigator
- Principal Investigator
  
  KATO Yoshihisa
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tokushima Bunri University
Species differences among mice, hamsters, rats and guinea pigs in PCB-induced alteration of serum thyroid hormone levelPrincipal Investigator
- Principal Investigator
  
  KATO Yoshihisa
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Shizuoka
Methylsulfonyl metabolites of polychlorinated biphenyl and polybrominated biphenyl as disrupters of endocrine actionPrincipal Investigator
- Principal Investigator
  
  KATO Yoshihisa
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  University of Shizuoka
The role of 3-methylsulfony (3-MeSOィイD22ィエD2) metabolites in the induction of hepatic microsomal drug-metabolizing enzymes by PCB congeners, and the toxicological effects of the MeSOィイD22ィエD2 metabolites of PCB congenersPrincipal Investigator
- Principal Investigator
  
  KATO Yoshihisa
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  University of Shizuoka

[Book] Persistent Organic Pollutants (POPs) Research in Asia(Edited by Masatoshi Morita)(The formation of a catechol metabolite of 2,2',4,5,5'-pentachlorobiphenyl (CB101) by liver microsomes from rats, hamsters, guinea pigs and humans.)2008
- Author(s)
  Nobuyuki Koga, Chiho Ohta, Koichi Haraguchi, Mikiko Matsuoka, Yoshihisa Kato, Tetsuya Endo
- Publisher
  The DIOXIN2007 International symposium organizing committee.
- Data Source
  KAKENHI-PROJECT-20510070
[Book] Persistent Organic Pollutants (POPs) Research in Asia(Edited by Masatoshi Morita)(The distribution of metabolites of 2,2',3,4,4',5',6-heptachlorobiphenyl (CB183) in rats and guinea pigs.)2008
- Author(s)
  Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Mikiko Matsuoka, Tetsuya Endo, Nobuyuki Koga
- Publisher
  The DIOXIN2007 International symposium organizing committee.
- Data Source
  KAKENHI-PROJECT-20510070
[Book] 甲状腺ホルモン撹乱物質の生体作用の動物種差.生体統御システムと内分泌撹乱2005
- Author(s)
  加藤善久
- Total Pages
  7
- Publisher
  シュプリンガー・フェアラーク東京
- Data Source
  KAKENHI-PROJECT-15510058
[Book] 生体統御システムと内分泌撹乱、甲状腺ホルモン撹乱物質の生体作用の動物種差2005
- Author(s)
  加藤善久
- Total Pages
  7
- Publisher
  シュプリンガー・フェアラーク東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Effects of perfluoroalkyl carboxylic acids on the uptake of sulfobromophthalein via organic anion transporting polypeptides in human intestinal Caco-2 cells.2020
- Author(s)
  Kimura Osamu、Fujii Yukiko、Haraguchi Koichi、Kato Yoshihisa、Ohta Chiho、Koga Nobuyuki、Endo Tetsuya
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 24 Pages: 100807-100807
- DOI
  10.1016/j.bbrep.2020.100807
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11660, KAKENHI-PROJECT-17K00574
[Journal Article] Perfluorinated carboxylic acods in edible clams: A possible exposure source of perfluorooctanoic acid for Japanese population.2020
- Author(s)
  Fujii Yukiko、Harada Kouji H.、Nakamura Tsubasa、Kato Yoshihisa、Ohta Chiho、Koga Nobuyuki、Kimura Osamu、Endo Tetsuya、Koizumi Akio、Haraguchi Koichi
- Journal Title
  
  Environmental Pollution
  
  Volume: 263 Pages: 114369-114369
- DOI
  10.1016/j.envpol.2020.114369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K11660, KAKENHI-PROJECT-17K00574
[Journal Article] Kanechlor 500-mediated changes in serum and hepatic thyroxine levels primarily occur in a transthyretin-unrelated manner2019
- Author(s)
  Kato Y, Tamaki S, Haraguchi K, Ikushiro S, Fujii Y, Ohta C, Atobe K, Kimura O, Endo T, Koga N, Yamada S, Degawa M
- Journal Title
  
  J. Appl. Toxicol.
  
  Volume: 39 Pages: 1701-1709
- DOI
  10.1002/jat.3895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K00574, KAKENHI-PROJECT-18K11660
[Journal Article] Levels and profiles of long-chain perfluoroalkyl carboxylic acids in Pacific cod from 14 sites in the North Pacific Ocean2019
- Author(s)
  Fujii Yukiko、Tuda Hayato、Kato Yoshihisa、Kimura Osamu、Endo Tetsuya、Harada Kouji H.、Koizumi Akio、Haraguchi Koichi
- Journal Title
  
  Environ. Pollut.
  
  Volume: 247 Pages: 312-318
- DOI
  10.1016/j.envpol.2019.01.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K00574, KAKENHI-PROJECT-16K00565, KAKENHI-PROJECT-18K11660
[Journal Article] 2,2',3,4',5,6,6'-七塩素化ビフェニル(CB188)のラットおよびモルモット肝ミクロゾームによる代謝2019
- Author(s)
  太田千穂、山本健太、加藤善久、藤井由希子、原口浩一、木村　治、遠藤哲也、古賀信幸
- Journal Title
  
  福岡医学雑誌
  
  Volume: 110 Pages: 83-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K11660
[Journal Article] Polychlorinated biphenylsによる血中甲状腺ホルモン濃度低下作用機構の解明：動物種差2018
- Author(s)
  加藤善久
- Journal Title
  
  Endocrine Disrupter News Letter
  
  Volume: 21-2 Pages: 4-4
- Data Source
  KAKENHI-PROJECT-18K11660
[Journal Article] Different profiles of naturally produced and anthropogenic organohalogens in the livers of cetaceans from the Sea of Japan and the North Pacific Ocean.2018
- Author(s)
  Fujii Yukiko、Kato Yoshihisa、Kozai Mai、Matsuishi Takashi、Harada Kouji H.、Koizumi Akio、Kimura Osamu、Endo Tetsuya、Haraguchi Koichi
- Journal Title
  
  Mar. Pollut. Bull.
  
  Volume: 136 Pages: 230-242
- DOI
  10.1016/j.marpolbul.2018.08.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K00574, KAKENHI-PROJECT-18K11660, KAKENHI-PROJECT-16K00565
[Journal Article] Metal concentrations in the liver and stable isotope ratios of carbon and nitrogen in the muscle of silvertip shark (Carcharhinus albimarginatus) culled off Ishigaki Island, Japan: changes with growth.2016
- Author(s)
  Endo, T., Kimura, O., Ohta, C., Koga, N., Kato, Y., Fujii, Y., Haraguchi, K.
- Journal Title
  
  PLOS ONE
  
  Volume: 11 Pages: 1-18
- DOI
  10.1371/journal.pone.0147797
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26881008, KAKENHI-PROJECT-26340043
[Journal Article] Metabolism of 2,2',3,4,4',5,6'- heptachlorobiphenyl (CB182) by rat, guinea pig and human liver microsomes.2016
- Author(s)
  Chiho Ohta, Yukiko Fujii, Koichi Haraguchi, Yoshihisa Kato, Osamu Kimura, Tetsuya Endo, Nobuyuki Koga
- Journal Title
  
  Organohalogen Compounds
  
  Volume: 78 Pages: 870-872
- NAID
  120006318699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340043
[Journal Article] Induction of hepatic T4 transporters by polychlorinated biphenyl in rats.2016
- Author(s)
  Yoshihisa Kato, Koichi Haraguchi, Aki Fujii, Yukiko Fujii, Osamu Kimura, Chiho Ohta, Tetsuya Endo, Nobuyuki Koga, Shizuo Yamada, and Masakuni Degawa
- Journal Title
  
  Organohalogen Compounds
  
  Volume: 78 Pages: 873-876
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26340043
[Journal Article] Effect of quercetin on the uptake and efflux of aristolochic acid I from Caco-2 cell monolayers.2016
- Author(s)
  Kimura, O., Fujii, Y., Haraguchi, K., Ohta, C., Koga, N., Kato, Y., Endo, T
- Journal Title
  
  J. Pharm. Pharmacol.
  
  Volume: - Pages: 2042-7158
- DOI
  10.1111/jphp.12557
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26881008, KAKENHI-PROJECT-26340043
[Journal Article] Mercury, cadmium, zinc and copper concentrations and stable isotope ratios of carbon and nitrogen in tiger sharks (Galeocerdo cuvier) culled off Ishigaki Island, Japan.2015
- Author(s)
  Tetsuya Endo, Osamu Kimura, Hideki Ogasawara, Chiho Ohta, Nobuyuki Koga, Yoshihisa Kato, Koichi Haraguchi
- Journal Title
  
  Ecol. Indic.
  
  Volume: 55 Pages: 86-93
- DOI
  10.1016/j.ecolind.2015.03.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340043
[Journal Article] 2,2',3,4',4,5,5'-七塩素化ビフェニル（CB180）の動物肝ミクロゾームによる代謝.2015
- Author(s)
  太田千穂、原口浩一、加藤善久、遠藤哲也、木村　治、古賀信幸
- Journal Title
  
  福岡医学雑誌
  
  Volume: 106 Pages: 176-183
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26340043
[Journal Article] Cyclosporin A-sensitive cytotoxicity of flurbiprofen nonstereoselectively mediated by cytochrome P450 metabolism in three-dimensional cultured rat hepatocytes.2015
- Author(s)
  Tadatoshi Tanino, Yoshinori Funakami, Noriaki Nagai, Yoshihisa Kato
- Journal Title
  
  Journal of Pharmacy and Pharmacology
  
  Volume: 67 Pages: 1406-1415
- DOI
  10.1111/jphp.12443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26340043
[Journal Article] Distribution and excretion of 2,2',3,4',5,5',6-heptachlorobiphenyl (CB187) and its metabolites in rats and guinea pigs.2015
- Author(s)
  Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo, Osamu Kimura, Nobuyuki Koga
- Journal Title
  
  Chemosphere
  
  Volume: 118 Pages: 5-11
- DOI
  10.1016/j.chemosphere.2014.05.019
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23510083, KAKENHI-PROJECT-26340043
[Journal Article] Distribution and excretion of　2,2′,3,4′,5,5′,6-heptachlorobiphenyl (CB187) and its metabolites in rats and guinea pigs.2015
- Author(s)
  Ohta, C.; Haraguchi, K.; Kato, Y.; Endo, T.; Kimura, O.; Koga, N.
- Journal Title
  
  Chemosphere
  
  Volume: 118 Pages: 5-11
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24310049
[Journal Article] 3,3′,4,4′-Tetrachlorobiphenyl-Mediated Decrease of Serum Thyroxine Level in C57BL/6 and DBA/2 Mice Occurs Mainly through Enhanced Accumulation of Thyroxine in the Liver2014
- Author(s)
  Yoshihisa Kato, Koichi Haraguchi, Mao Onishi, Shinichi Ikushiro, Tetsuya Endo, Chiho Ohta, Nobuyuki Koga, Shizuo Yamada, and Masakuni Degawa
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 37 Issue: 3 Pages: 504-509
- DOI
  10.1248/bpb.b13-00775
- NAID
  130003382126
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23510083, KAKENHI-PROJECT-24310049, KAKENHI-PROJECT-26340043
[Journal Article] Dietary exposure to phenolic and methoxylated organohalogen contaminants in relation to their concentration in breast milk and serum in Japan2014
- Author(s)
  Fujii, Y., Eri, Nishimura., Kato, Y., Harada, K.H., Koizumi, A., Haraguchi, K.
- Journal Title
  
  Environment International
  
  Volume: 63 Pages: 19-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310049
[Journal Article] The participation of rat CYP3A enzymes in the metabolism of 2,2',4,5,5'-pentachlorobiphenyl (CB101)2014
- Author(s)
  Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo, Nobuyuki Koga
- Journal Title
  
  Organohalogen Compounds
  
  Volume: 76 Pages: 466-469
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26340043
[Journal Article] Uptake of Aristolochic Acid I into Caco-2 Cells by Monocarboxylic Acid Transporters2014
- Author(s)
  Osamu Kimura, Koichi Haraguchi, Chiho Ohta, Nobuyuki Koga, Yoshihisa Kato, Tetsuya Endo
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 37 Issue: 9 Pages: 1475-1479
- DOI
  10.1248/bpb.b14-00219
- NAID
  130004684786
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510083, KAKENHI-PROJECT-24310049, KAKENHI-PROJECT-25303011, KAKENHI-PROJECT-26340043
[Journal Article] Carrier-mediated uptake of nobiletin, a citrus polymethoxyflavonoid, in human intestinal Caco-2 cells.2014
- Author(s)
  Osamu Kimura, Chiho Ohta, Nobuyuki Koga, Koichi Haraguchi, Yoshihisa Kato, and Tetsuya Endo
- Journal Title
  
  Food Chemistry
  
  Volume: 154 Pages: 145-150
- DOI
  10.1016/j.foodchem.2013.12.069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510083, KAKENHI-PROJECT-25303011, KAKENHI-PROJECT-26340043
[Journal Article] The participation of rat CYP3A enzymes in the metabolism of 2,2',4,5,5'-pentachlorobiphenyl (CB101)2014
- Author(s)
  Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo, Nobuyuki Koga
- Journal Title
  
  Organohalogen Compounds
  
  Volume: 76 Pages: 466-469
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23510083
[Journal Article] Dietary exposure to phenolic and methoxylated organohalogen contaminants in relation to their concentrations in breast milk and serum in Japan2014
- Author(s)
  Fuiii, Y. ; Nishimura, E. ; Kato, Y . ; Harada, K. H. ; Koizumi, A. ; Haraguchi, K.
- Journal Title
  
  Environ. Int
  
  Volume: 63 Pages: 19-25
- DOI
  10.1016/j.envint.2013.10.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05348, KAKENHI-PROJECT-23510083, KAKENHI-PROJECT-23590739, KAKENHI-PROJECT-26340043
[Journal Article] In vitro metabolism of 2,2',4,4',5-pentachlorobiphenyl (CB99) by rat and guinea pig liver microsomes2013
- Author(s)
  Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo, Osamu Kimura, Nobuyuki Koga
- Journal Title
  
  Organohalogen Compounds
  
  Volume: 75 Pages: 587-590
- Data Source
  KAKENHI-PROJECT-23510083
[Journal Article] ラットおよびモルモットの小腸と腎におけるノビレチンの代謝2013
- Author(s)
  太田千穂、加藤善久、原口浩一、遠藤哲也、古賀信幸
- Journal Title
  
  中村学園大学・中村学園大学短期大学部研究紀要
  
  Volume: 45 Pages: 141-149
- NAID
  120005724201
- Data Source
  KAKENHI-PROJECT-23510083
[Journal Article] Levels of mercury in the muscle and liver of star-spotted dogfish (Mustelus manazo) in the northern region of Japan: A comparison with spiny dogfish (Squalus acanthias)2013
- Author(s)
  Tetsuya Endo, Yohsuke Hisamichi, Osamu Kimura, Hideki Ogasawara, Chiho Ohta, Nobuyuki Koga, Yoshihisa Kato, and Koichi Haraguchi
- Journal Title
  
  Arch Environ Contam Toxicol
  
  Volume: 64 Pages: 467-474
- DOI
  10.1007/s00244-012-9858-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510083, KAKENHI-PROJECT-24310049, KAKENHI-PROJECT-25303011
[Journal Article] 2,2',3,4',5,5'-六塩素化ビフェニル（CB146）のin vitro代謝の動物種差2013
- Author(s)
  太田千穂、原口浩一、加藤善久、遠藤哲也、古賀信幸
- Journal Title
  
  福岡医学雑誌
  
  Volume: 104 Pages: 161-169
- Data Source
  KAKENHI-PROJECT-23510083
[Journal Article] A possible mechanism for 2,3',4,4',5'-pentachlorobiphenyl-mediated decrease in serum thyroxine level in mice.2013
- Author(s)
  Kato, Y., Onishi, M., Haraguchi, K., Ikushiro, S., Ohta, C., Koga, N., Endo, T., Yamada, S., Degawa, M.
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 36 Pages: 1594-1601
- NAID
  130003361538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24310049
[Journal Article] Involvement of α4β2 nicotinic acetylcholine receptors in working memory impairment induced by repeated electroconvulsive seizures in rats2013
- Author(s)
  Hidaka N, Suemaru K, Kato Y, Araki H.
- Journal Title
  
  Epilepsy Research
  
  Volume: 104 Pages: 181-185
- DOI
  10.1016/j.eplepsyres.2012.09.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590082, KAKENHI-PROJECT-23510083
[Journal Article] A Possible Mechanism for 2,3′,4,4′,5′-Pentachlorobiphenyl-Mediated Decrease in Serum Thyroxine Level in Mice2013
- Author(s)
  Yoshihisa Kato, Mao Onishi, Koichi Haraguchi, Shinichi Ikushiro, Chiho Ohta, Nobuyuki Koga, Tetsuya Endo, Shizuo Yamada, and Masakuni Degawa
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 36 Issue: 10 Pages: 1594-1601
- DOI
  10.1248/bpb.b13-00440
- NAID
  130003361538
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510083
[Journal Article] 2,2',4,5,5'-Pentachlorobiphenyl-mediated inhibition of a serum T4-transthyretin complex formation is one of causes for the PCB-induced changes in the serum and hepatic T4 levels in mice.2012
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Organohalogen Compds
  
  Volume: 74 Pages: 1377-1380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510083
[Journal Article] Selective determination of mono and dihydroxylated analogs of polybrominated diphenyl ethers in marine sponges by liquid-chromatography tandem mass2012
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Analytical and Bioanalytical Chemistry
  
  Volume: 404 Pages: 197-206
- DOI
  10.1007/s00216-012-6132-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510083, KAKENHI-PROJECT-24310049
[Journal Article] Comparative study on 2,2',4,5,5'-pentachlorobiphenyl-mediated decrease in serum thyroxine level between C57BL/6 and its transthyretin-deficient mice.2012
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Toxicol. Appl. Pharmacol.
  
  Volume: 263 Pages: 323-329
- DOI
  10.1016/j.taap.2012.07.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510083
[Journal Article] 2,2',4,4',5,5'-Hexachlorobiphenyl-mediated decrease in serum thyroxine level in mice2011
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Organohalogen Compounds
  
  Volume: 73 Pages: 726-729
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510083
[Journal Article] A possible mechanism for 2,2',4,4',5,5'-hexachlorobiphenyl-mediated decrease in serum thyroxine level in mice2011
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Toxicol. Appl. Pharmacol.
  
  Volume: 254 Pages: 48-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510083
[Journal Article] Polychlorinated biphenyl-mediated decrease in serum thyroxine level in rodents.2010
- Author(s)
  Yoshihisa Kato, Koichi Haraguchi, Yuriko Ito, Aki Fujii, Tomoaki Yamazaki, Tetsuya Endo, Nobuyuki Koga, Shizuo Yamada, Masakuni Degawa
- Journal Title
  
  Drug Metab.Dispos. 38
  
  Pages: 697-704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] A possible mechanism for the decrease in serum thyroxine level by a 2,3,7,8-tetrachlorodibenzo-p-dioxin-like polychlorinated biphenyl congener, 3,3',4,4',5-pentachlorobiphenyl in mice2010
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab.Dispos. 38
  
  Pages: 150-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] A possible mechanism for the decrease in serum thyroxine level by a 2,3,7,8-tetrachlorodibenzo-p-dioxin-like polychlorinated biphenyl congener, 3,3',4,4',5-pentachlorobiphenyl in mice.2010
- Author(s)
  Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Takashi Okura, Shin-ichi Ikushiro, Nobuyuki Koga, Shizuo Yamada, Masakuni Degawa
- Journal Title
  
  Drug Metab.Dispos. 38
  
  Pages: 150-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] A possible mechanism for the decrease in serum thyroxine level by phenobarbital in rodents.2010
- Author(s)
  Yoshihisa Kato, Hiroshi Suzuki, Koichi Haraguchi, Shinichi Ikushiro, Yoshihiko Ito, Shinya Uchida, Shizuo Yamada, Masakuni Degawa
- Journal Title
  
  Toxicol.Appl.Pharmacol. 249
  
  Pages: 238-246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] Polychlorinated biphenyl-mediated decrease in serum thyroxine level in rodents.2010
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab.Dispos.
  
  Volume: 38 Pages: 697-704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] Polychlorinated biphenyl-mediated decrease in serum thyroxine level in rodents2010
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab.Dispos. 38
  
  Pages: 697-704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] A possible mechanism for the decrease in serum thyroxine level by phenobarbital in rodents.2010
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Toxicol.Appl.Pharmacol.
  
  Volume: 249 Pages: 238-246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] A possible mechanism for the decrease in serum thyroxine level by a 2,3,7,8-tetrachlorodibenzo-p-dioxin-like polychlorinated biphenyl congener, 3,3',4,4',5-pentachlorobiphenyl in mice.2010
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab.Dispos.
  
  Volume: 38 Pages: 150-156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] Simultaneous determination by APCI-LC/MS/MS of hydroxylated and methoxylated polybrominated diphenyl ethers found in marine biota.2009
- Author(s)
  Kato Y, Okada S, Atobe K, Endo T, Matsubara F, Oguma T, Haraguchi K.
- Journal Title
  
  Analytical Chemistry 81
  
  Pages: 5942-5948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310042
[Journal Article] Simultaneous determination by APCI-LC/MS/MS of hydroxylated and methoxylated polybrominated diphenyl ethers found in marine biota2009
- Author(s)
  Y.Kato
- Journal Title
  
  Analytical Chemistry 81
  
  Pages: 5942-5948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310042
[Journal Article] 4-Hydroxy-2,2',3,4',5,5',6-heptachlorobiphenyl-mediated decrease in serum thyroxine level in mice occurs through increase in accumulation of thyroxin in the liver2009
- Author(s)
  Y.Kato
- Journal Title
  
  Drug Metabolism & Disposition 37
  
  Pages: 2095-2102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310042
[Journal Article] Simultaneous determination by APCI-LC/MS/MS of hydroxylated and methoxylated polybrominated diphenyl ethers found in marine biota2009
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Anal.Chem. 81
  
  Pages: 5942-5948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] A possible mechanism for the decrease in serum thyroxine level by TCDD-like PCB, 3,3',4,4',5-pentachlorobiphenyl in mice2009
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Organohalogen Compounds 71
  
  Pages: 119-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] 4-Hydroxy-2,2',3,4',5,5',6-heptachlorobiphenyl-mediated decrease in serum thyroxine level in mice occurs through increase in accumulation of thyroxine in the liver2009
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab.Dispos. 37
  
  Pages: 2095-2102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] 2,2',5,5'-四塩素化ビフェニル(CB52)のウサギ肝ミクロゾームによる代謝2009
- Author(s)
  太田千穂、原口浩一、加藤善久、遠藤哲也、古賀信幸
- Journal Title
  
  福岡医学雑誌 100
  
  Pages: 200-209
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] Halogenated bipyrroles and methoxylated tetrabromodiphenyl ethers in tiger shark (Galeocerdo cuvier) from the southern coast of Japan2009
- Author(s)
  Haraguchi K, Hisamichi Y, Kotaki Y, Kato Y, Endo T.
- Journal Title
  
  Environ. Sci. Technol. 43
  
  Pages: 2288-2294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310042
[Journal Article] Simultaneous determination by APCILC/MS/MS of hydroxylated and methoxylated polybrominated diphenyl ethers found in marine biota.2009
- Author(s)
  Yoshihisa Kato, Syohei Okada, Kazutaka Atobe, Tetsuya Endo, Futoshi Matsubara, Takayoshi Oguma, Koichi Haraguchi
- Journal Title
  
  Anal.Chem. 81
  
  Pages: 5942-5948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] 4-Hydroxy-2, 2', 3, 4', 5, 5', 6-heptachlorobiphenyl-mediated decrease in serum thyroxine level in mice occurs through increase in accumulation of thyroxine in the liver.2009
- Author(s)
  Kato Y, Haraguchi K, Kubota M, Seto S, Ikushiro S, Sakaki T, Koga N, Yamada S, Degawa M.
- Journal Title
  
  Drug Metab. Dispos. 37
  
  Pages: 2095-2102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310042
[Journal Article] 4-Hydroxy-2,2',3,4',5,5',6-heptachlorobiphenyl-mediated decrease in serum thyroxine level in mice occurs through increase in accumulation of thyroxine in the liver.2009
- Author(s)
  Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Yoshiki Seto, Shin-ichi Ikushiro, Toshiyuki Sakaki, Nobuyuki Koga, Shizuo Yamada, Masakuni Degawa
- Journal Title
  
  Drug Metab.Dispos. 37
  
  Pages: 2095-2102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] Levels and regional trends of persistent organochlorines and polybrominated diphenyl ethers in Asian breast milk demonstrate POPs signatures unique to individual countries.2009
- Author(s)
  Koichi Haraguchi, Akio Koizumi, Kayoko Inoue, Kouji H. Harada, Toshiaki Hitomi, Mutsuko Minata, Miyako Tanabe, Yoshihisa Kato, Eri Nishimura, Yoshiaki Yamamoto, Takao Watanabe, Katsunobu Takenaka, Shigeki Uehara, Hye-Ran Yang, Min-Young Kim, Chan-Seok Moon, Hae-Sook Kim, Peiyu Wang, Aiping Liu, Nguyen Ngoc Hung
- Journal Title
  
  Environ. Int. 35
  
  Pages: 1072-1079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] A possible mechanism for the decrease in serum thyroxine level by 4-OH-2, 2', 3, 4', 5, 5', 6-heptachlorobiphenyl in mice.2008
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Organohalogen Compounds 70
  
  Pages: 1601-1604
- NAID
  130007002557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] Hepatic UDPglucuronosyltransferases responsible for glucuronidation of thyroxine T4 in humans.2008
- Author(s)
  Yoshihisa Kato, Shin-ichi Ikushiro, Yoshikazu Emi, Sekihiro Tamaki, Hiroshi Suzuki, Toshiyuki Sakaki, Shizuo Yamada, Masakuni Degawa
- Journal Title
  
  Drug Metab.Dispos. 36
  
  Pages: 51-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] Hepatic UDP-glucuronosyltransferases responsible for glucuronidation of thyroxine in humans2008
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab.Dispos 36
  
  Pages: 51-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510061
[Journal Article] Negative APCI-LC/MS/MS method for determination of natural persistent halogenated products in marine biota.2008
- Author(s)
  Haraguchi K, Kato Y, Atobe K, Okada S, Endo T, Matsubara F, Oguma T.
- Journal Title
  
  Analytical Chemistry 80
  
  Pages: 9748-9755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310042
[Journal Article] Hepatic UDP-glucuronosyltransferases responsible for glucuronidation of thyroxine in humans.2008
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab. Dispos. 36
  
  Pages: 51-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510061
[Journal Article] Negative APCI-LC/MS/MS method for determination of natural persistent halogenated products in marine biota.2008
- Author(s)
  Koichi Haraguchi, Yoshihisa Kato, Kazutaka Atobe, Syohei Okada, Tetsuya Endo, Futoshi Matsubara, Takayoshi Oguma
- Journal Title
  
  Anal.Chem. 80
  
  Pages: 9748-9755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] Hepatic UDP-glucuronosyltransferases responsible for glucuronidation of thyroxine in humans.2008
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab. Dispos. 36
  
  Pages: 51-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510070
[Journal Article] Hepatic UDP-glucuronosyltransferases responsible for glucuronidation of thyroxine in humans2008
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab.Dispos. 36
  
  Pages: 51-55
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510061
[Journal Article] A novel mechanism for polychlorinated biphenyl-induced decrease in serum thyroxine level in rats2007
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab.Dispos. 35
  
  Pages: 1949-1955
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510061
[Journal Article] Comparative study on nobiletin metabolism with liver microsomes from rats, guinea pigs and hamsters and rat cytochrome P4502007
- Author(s)
  Koga N, Matsuo M, Ohta C, Haraguchi K, Matsuoka M, Kato Y, Ishii T, Yano M, Ohta H.
- Journal Title
  
  Biol. Pharm. Bull. 30
  
  Pages: 2317-2323
- NAID
  110006546432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310042
[Journal Article] A novel mechanism for polychlorinated biphenyl-induced decrease in serum thyroxine level in rats.2007
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab. Dispos. 35
  
  Pages: 1949-1955
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510061
[Journal Article] Anovel mechanisnl for polychlorhlated biphenyl-induced decrease inserum thyroxine level in rats2007
- Author(s)
  Kato Y
- Journal Title
  
  Drug Metabolism and Disposition 35
  
  Pages: 1949-1955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19310042
[Journal Article] A novel mechanism for polychrinated biphenyl-induced decrease in serum thyroxine level in rats2007
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab.Dispos 35
  
  Pages: 1949-1955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510061
[Journal Article] A possible mechanism for the decrease in serum thyroxine level by polychlorinated biphenyls in Wistar and Gunn rats2006
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Organohalogen Compounds 68
  
  Pages: 1442-1445
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510061
[Journal Article] A possible mechanism for the decrease in serum thytoxine level by polychlorinated biphenyls in Wistar and Gunn rats.2006
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Organohalogen Compounds 68
  
  Pages: 1442-1445
- Data Source
  KAKENHI-PROJECT-18510061
[Journal Article] A possible mechanism for the decrease in serum thyroxine level by polychlorinated biphenyls in Wistar and Gunn rats.2006
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Organohalonen Compd. 68
  
  Pages: 1442-1445
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510061
[Journal Article] The decrease in level of serum thyroxine by 2,2',4,5,5'-pentachlorobiphenyl in rats and mice : No correlation with formation of methylsulfonyl metabolites.2005
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab.Dispos. 33
  
  Pages: 1661-1665
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] The decrease in level of serum thyroxine by 2,2',4,5,5'-pentachlorobiphenyl in rats and mice: No correlation with formation of methylsulfonyl metabolites2005
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab.Dispos. 33
  
  Pages: 1661-1665
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] The decrease in level of serum thyroxine by 2,2',4,5,5'-pentachlorobiphenyl in rats and mice : No correlation with formation of methylsulfonyl metabolites2005
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab.Dispos. 33
  
  Pages: 1661-1665
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Decrease in serum thyroxine level by phenobarbital in rats is not necessarily dependent on increase in hepatic UDP-glucuronosyltransferase2005
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab.Dispos. 33
  
  Pages: 1608-1612
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Decrease in serum thyroxine level by phenobarbital in rats is not necessarily dependent on increase in hepatic UDP-glucuro-nosyltransferase.2005
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Drug Metab.Dispos. 33
  
  Pages: 1608-1612
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Polychlorinated biphenylsによる血中サイロキシン濃度低下作用機構2004
- Author(s)
  加藤善久
- Journal Title
  
  Endocrine Disrupter News Letter 7
  
  Pages: 2-2
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] A possible mechanism for decrease in serum thyroxine level by polychlorinated biphenyls in Wistar and Gunn rats2004
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Toxicol.Sci. 81
  
  Pages: 309-315
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Species differences among mice, hamsters, rats and guinea pigs in PCB-induced alteration of serum thyroid hormone level.2004
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Environ.Mutagen Res. 26
  
  Pages: 101-106
- NAID
  10013956799
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] A possible mechanism for decrease in serum thyroxine level by polychlorinated biphenyls in Wistar and Gunn rats.2004
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Toxicol.Sci. 81
  
  Pages: 309-315
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] PCB類による甲状腺ホルモンかく乱作用とその作用機構:動物種差2004
- Author(s)
  加藤善久
- Journal Title
  
  環境変異原研究 26
  
  Pages: 101-106
- NAID
  10013956799
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Species difference among mice, hamsters, rats and guinea pigs in Kanechlor-500-induced alterations of serum thyroid hormone level.2003
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Organohalogen Compd. 64
  
  Pages: 316-319
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Species difference among mice, hamsters, rats, and guinea pigs in 2,2',4',5,5'-pentachlorobiphenyl or 2, 2',3',4',5,6-hexachlorobiphenyl-induced alteration of serum thyroid hormone level2003
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  J.Toxicol.Sci. 28
  
  Pages: 322-322
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Species difference among mice, hamsters, rats, and guinea pigs in Kanechlor-500-induced alteration of serum thyroid hormone level.2003
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  J Toxicol. Sci. 28
  
  Pages: 321-321
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Effects of polychlorinated biphenyls, Kanechlor-500, on serum thyroid hormone levels in rats and mice.2003
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Toxicol.Sci. 72
  
  Pages: 235-241
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Effects of polychlorinated biphenyls, Kanechlor-500, on serum thyroid hormonelevels in rats and mice2003
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Toxicol.Sci. 72
  
  Pages: 235-241
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Species difference among mice, hamsters, rats, and guinea pigs in Kanechlor-500-induced alteration of serum thyroid hormone level2003
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  J.Toxicol.Sci. 28
  
  Pages: 321-321
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Species difference among mice, hamsters, rats and guinea pigs in 2,2',4',5,5'-pentachlorobiphenyl and 2,2',3',4',5,6-hexachlorobiphenyl-induced alterations of serum thyroid hormone level2003
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Organohalogen Compd. 64
  
  Pages: 332-335
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Species difference among mice, hamsters, rats and guinea pigs in 2,2',4',5,5'-pentachlorobiphenyl and 2,2',3',4',5,6-hexachlorobiphenyl-induced alterations of serum thyroid hormone level.2003
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Organohalogen Compd. 64
  
  Pages: 332-335
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Species difference among mice, hamsters, rats and guinea pigs in Kanechlor-500-induced alterations of serum thyroid hormone level2003
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  Organohalogen Compd. 64
  
  Pages: 316-319
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Journal Article] Species difference among mice, hamsters, rats, and guinea pigs in 2,2',4',5,5'-pentachlorobiphenyl or 2,2',3',4',5,6-hexachlorobiphenyl-induced alteration of serum thyroid hormone level.2003
- Author(s)
  Yoshihisa Kato
- Journal Title
  
  J. Toxicol. Sci. 28
  
  Pages: 322-322
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15510058
[Presentation] 2,2’,4,4’,6,6’-六塩素化ビフェニル(PCB155)のヒト肝ミクロゾームおよびチトクロムP450分子種による代謝2021
- Author(s)
  太田千穂，加藤善久，藤井由希子，原口浩一，木村治，遠藤哲也，古賀信幸
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K11660
[Presentation] 2,2',4,4',6,6'-六塩素化ビフェニル(PCB155)の動物肝ミクロゾームによる代謝2020
- Author(s)
  太田千穂，加藤善久，原口浩一，藤井由希子，木村治，遠藤哲也，古賀信幸
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K11660
[Presentation] レスベラトロール封入リポソームの調製法についての検討2020
- Author(s)
  跡部一孝、長尾知佳、加藤善久
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K11660
[Presentation] 医薬品や化学物質による血中甲状腺ホルモン濃度低下作用機構の薬物動態学的解明2019
- Author(s)
  加藤善久
- Organizer
  中村学園大学大学院栄養科学研究科博士後期課程講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18K11660
[Presentation] Seafood in lower trophic level is a possible source of human dietary exposure: perfluorinated carboxylic acids in Manila clam (Ruditapes philippinarum) in Japan2019
- Author(s)
  Fujii Y., Nakamura T., Harada K.H., Kato Y., Ohta C., Koga N., Kimura O., Endo T., Koizumi A., Haraguchi K.
- Organizer
  39th International Symposium on Halogenated Persistent Organic Pollutants
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11660
[Presentation] Human exposure to brominated phenoxy phenols: seaweeds as source of hydroxylated and methoxylated PBDEs in Asia-Pacific.2018
- Author(s)
  Haraguchi K., Fujii Y., Ohta C., Koga N., Kimura O., Endo T., Kato Y.
- Organizer
  38th International Symposium on Halogenated Persistent Organic Pollutants
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11660
[Presentation] PCBによる血中甲状腺ホルモン濃度低下作用機構の解明2018
- Author(s)
  加藤善久
- Organizer
  環境ホルモン学会第32回講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18K11660
[Presentation] Involvement of transthyretin to Kanechlor-500-mediated changes in serum and hepatic thyroxine levels in mice.2018
- Author(s)
  Kato Y., Tamaki S., Haraguchi K., Fujii Y., Kimura O., Ohta C., Endo T., Koga N., Degawa M.
- Organizer
  38th International Symposium on Halogenated Persistent Organic Pollutants
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11660
[Presentation] In vitro metabolism of 2,2',3,4',5,6,6'-heptachlorobiphenyl (CB188) by rat liver microsomes.2018
- Author(s)
  Ohta C., Yamamoto K., Fujii Y., Haraguchi K., Kimura O., Endo T., Kato Y., Koga N.
- Organizer
  38th International Symposium on Halogenated Persistent Organic Pollutants
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11660
[Presentation] 2,2',3,4,4',5,6'-七塩素化ビフェニル(CB182)の動物およびヒト肝ミクロゾームによる代謝2017
- Author(s)
  太田千穂, 藤井由希子, 原口浩一, 加藤善久, 木村　治, 遠藤哲也, 古賀信幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター、仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] Caco-2細胞におけるぺルフルオロオクタン酸の取り込み2017
- Author(s)
  木村治，藤井由希子，原口浩一，加藤善久，太田千穂，古賀信幸，遠藤哲也
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター、仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] Metabolism of 2,2',3,4,4',5,6'- heptachlorobiphenyl (CB182) by rat, guinea pig and human liver microsomes.2016
- Author(s)
  Ohta, C., Fujii, Y., Haraguchi, K., Kato, Y., Kimura, O., Endo, T., and Koga, N.
- Organizer
  36th International Symposium on Halogenated Persistent Organic Pollutants
- Place of Presentation
  Firenze, Italy
- Year and Date
  2016-08-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] 化学物質による血中甲状腺ホルモン濃度低下作用機構の薬物動態学的解明2016
- Author(s)
  加藤善久
- Organizer
  第2回バイオシグナル研究会
- Place of Presentation
  神戸大学、神戸
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] 大型海洋ほ乳類を用いた有機フッ素化合物の肝臓蓄積実態の解明2016
- Author(s)
  木下真璃伽，久我歩佳，藤井由希子，加藤善久，木村治，遠藤哲也，太田千穂，古賀信幸，原口浩一
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] Induction of hepatic T4 transporters by polychlorinated biphenyl in rats.2016
- Author(s)
  Kato, Y., Haraguchi, K., Fujii, A., Fujii, Y., Kimura, O., Ohta, C., Endo, T., Koga, N., Yamada, S., Degawa, M.
- Organizer
  36th International Symposium on Halogenated Persistent Organic Pollutants
- Place of Presentation
  Firenze, Italy
- Year and Date
  2016-08-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] Caco-2細胞におけるアリストロキア酸Iの膜透過に及ぼすケルセチンの影響2016
- Author(s)
  木村治，藤井由希子，原口浩一，太田千穂，古賀信幸，加藤善久，遠藤哲也
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] 医薬品や化学物質による血中甲状腺ホルモン濃度低下作用機構の解明2015
- Author(s)
  加藤善久
- Organizer
  静薬学友会四国支部大会
- Place of Presentation
  徳島
- Year and Date
  2015-11-29
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] PCBによる血中甲状腺ホルモン濃度低下作用機構の解明2015
- Author(s)
  加藤善久
- Organizer
  第3回 PCB講演会
- Place of Presentation
  神戸
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] 海洋生物由来臭素化合物のヒト肝酵素による代謝2015
- Author(s)
  太田千穂，西村恵理，原口浩一，遠藤哲也，加藤善久，山本健太，古賀信幸
- Organizer
  フォーラム2015：衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] 海洋生物由来のtetrabromoveratrole (TBV)の動物肝ミクロゾームによる代謝2014
- Author(s)
  太田千穂，西村恵理，原口浩一，遠藤哲也，加藤善久，山本健太，古賀信幸
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23510083
[Presentation] Caco-2細胞におけるアリストロキア酸の細胞内取込み機構2014
- Author(s)
  遠藤哲也，木村　治，原口浩一，太田千穂，古賀信幸，加藤善久
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23510083
[Presentation] In vitro metabolism of 2,2',4,4',5-pentachlorobiphenyl (CB99) by rat and guinea pig liver microsomes2013
- Author(s)
  Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo, Osamu Kimura and Nobuyuki Koga
- Organizer
  33rd International Symposium on Halogenated Persistent Organic Pollutants
- Place of Presentation
  Daegu, Korea
- Data Source
  KAKENHI-PROJECT-23510083
[Presentation] 海洋生物由来2,2’-dimethoxy-BB80のラット肝ミクロゾームによる代謝と抗酸化活性2013
- Author(s)
  西村恵理、太田千穂、原口浩一、遠藤哲也、加藤善久、古賀信幸
- Organizer
  フォーラム2013, 衛生薬学・環境トキシコロジー学会
- Place of Presentation
  九州大学（福岡市東区）
- Data Source
  KAKENHI-PROJECT-24310049
[Presentation] In vitro metabolism of diosmetin and hesperetin by rat liver microsomes2013
- Author(s)
  Chiho Ohta, Yoshihisa Kato, Koichi Haraguchi, and Nobuyuki Koga
- Organizer
  20th International Congress of Nutrition
- Place of Presentation
  Granada, Spein
- Data Source
  KAKENHI-PROJECT-23510083
[Presentation] In vitro metabolism of 2,2’,4,4’,5-pentachlorobiphenyl (CB99) by rat and guinea pig liver microsomes2013
- Author(s)
  Ohta C, Haraguchi K, Kato Y, Endo T, Kimura O, Koga N.
- Organizer
  33rd International Symposium on Halogenated Persistent Organic Pollutants and POPs
- Place of Presentation
  Daegu, Korea
- Data Source
  KAKENHI-PROJECT-24310049
[Presentation] 海洋生物由来2,2'-dimethoxy-BB80のラット肝ミクロゾームによる代謝と抗酸化活性2013
- Author(s)
  西村恵理，太田千穂，原口浩一，遠藤哲也，加藤善久，古賀信幸
- Organizer
  フォーラム2013：衛生薬学・環境トキシコロジー
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23510083
[Presentation] In vitro metabolism of 3,5,6,7,8,3’,4’-heptamethoxyflavone by rat liver microsomes2013
- Author(s)
  Nobuyuki Koga, Mikiko Matsuoka, Chiho Ohta, Yoshihisa Kato, Koichi Haraguchi, Osamu Kimura and Tetsuya Endo
- Organizer
  20th International Congress of Nutrition
- Place of Presentation
  Granada, Spein
- Data Source
  KAKENHI-PROJECT-23510083
[Presentation] 2,2',4,5,5'-Pentachlorobiphenyl-mediated inhibition of a serum T4-transthyretin complex formation is one of causes for the PCB-induced changes in the serum and hepatic T4 levels in mice.2012
- Author(s)
  Yoshihisa Kato
- Organizer
  32nd International Symposium on Halogenated Persistent Organic Pollutants
- Place of Presentation
  Queensland, Australia
- Data Source
  KAKENHI-PROJECT-23510083
[Presentation] PCB149のラット肝によるin vitro代謝:CYP3A酵素の関与2011
- Author(s)
  太田千穂、原口浩一、加藤善久、遠藤哲也、古賀信幸
- Organizer
  日本薬学会第131年会、講演要旨集3(p.237)
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] 2,2',4,4',5,5'-Hexachlorobiphenyl-mediated decrease in serum thyroxine level in mice2011
- Author(s)
  Yoshihisa Kato
- Organizer
  31st International Symposium on Halogenated Persistent Organic Pollutants
- Place of Presentation
  Brussels
- Data Source
  KAKENHI-PROJECT-23510083
[Presentation] 2,3',4,5,5'-五塩素化ビフェニル(PCB120)のラットおよびモルモット肝ミクロゾームによる代謝2010
- Author(s)
  太田千穂、原口浩一、加藤善久、遠藤哲也、松原大、古賀信幸
- Organizer
  フォーラム2010:衛生薬学・環境トキシコロジー、講演要旨集(p.211)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010
- Author(s)
  松原加奈、佐能正剛、岩瀬恵理、藤本成明、浦丸直人、杉原数美、加藤善久、北村繁幸、太田茂
- Organizer
  フォーラム2010:衛生薬学・環境トキシコロジー、講演要旨集(p.212)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] 2,2',3,4,4',5'-六塩素化ビフェニル(PCB138)のモルモットにおけるin vivo代謝2010
- Author(s)
  太田千穂、原口浩一、加藤善久、遠藤哲也、古賀信幸
- Organizer
  日本薬学会第130年会、講演要旨集3(p.247)
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] Species difference in the in vitro metabolism of 2,2',3,4,4',5,5'-heptachlorobiphenyl (CB180).2010
- Author(s)
  Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo, Futoshi Matsubara, Nobuyuki Koga
- Organizer
  30th International Symposium on Halogenated Persistent Organic Pollutants, Organohalogen Compounds(72 1796-1799)
- Place of Presentation
  San Antonio, USA.
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] 4-OH-2,2',3,4',5,5',6-heptachlorobiphenyl による血中甲状腺ホルモン濃度の低下作用機構の解明2009
- Author(s)
  加藤善久
- Organizer
  第36回日本トキシコロジー学会学術年会
- Place of Presentation
  盛岡
- Year and Date
  2009-07-08
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] A possible mechanism for the decrease in serum thyroxine level by TCDD-like PCB, 3,3',4,4',5-nentachlorobiphenyl in mice2009
- Author(s)
  加藤善久
- Organizer
  29th International Symposium on Halogenated Persistent Organic Pollutants
- Place of Presentation
  Beijing, China
- Year and Date
  2009-08-25
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] TR、PDIへの親和性に対する臭素化難燃剤の構造活性相関2009
- Author(s)
  岩瀬恵理、佐能正剛、今岡進、岡田和嗣、加藤善久、小島弘幸、浦丸直人、杉原数美、北村繁幸、黒木広明、太田茂
- Organizer
  フォーラム2009:衛生薬学・環境トキシコロジー、講演要旨集(p.314)
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] APCI-LC/MS/MS による臭素系汚染物質、polybrominated diphenyl ethers(PBDEs)、methoxy PBDEs、hydroxy(OH-)PBDEsの同時定量法の確立:サメ肝臓よりOH-PBDEsを検出2009
- Author(s)
  加藤善久、岡田将平、跡部一孝、松原大、遠藤哲也、尾熊隆嘉、原口浩一
- Organizer
  第36回日本トキシコロジー学会学術年会、講演要旨集、J.Toxicol.Sci.(34 Supp. S146)
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] APCI-LC/MS/MSによる天然のポリ臭化ジフェニルエーテル関連化合物の探索:海綿抽出物から創薬への応用をめざして2009
- Author(s)
  岡田将平、加藤善久、跡部一孝、松原大、遠藤哲也、尾熊隆嘉、原口浩一
- Organizer
  第48回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-19310042
[Presentation] Metabolism of 2,2',3,4',5',6-hexachlorobiphenyl (CB149) by liver microsomes from rats, hamsters, guinea pigs and humans.2009
- Author(s)
  Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo, Nobuyuki Koga
- Organizer
  29th International Symposium on Halogenated Persistent Organic Pollutants, Organohalogen Compounds(71 308-311)
- Place of Presentation
  Beijing, China.
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] A possible mechanism for the decrease in serum thyroxine level by TCDD-like PCB, 3,3',4,4',5-pentachlorobiphenyl in mice.2009
- Author(s)
  Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Shin-ichi Ikushiro, Toshiyuki Sakaki, Nobuyuki Koga, Shizuo Yamada, Masakuni Degawa
- Organizer
  29th International Symposium on Halogenated Persistent Organic Pollutants, Organohalogen Compounds(71 119-122)
- Place of Presentation
  Beijing, China.
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] 環境化学物質の甲状腺ホルモン受容体結合活性とその代謝変動2009
- Author(s)
  佐能正剛、岩瀬恵理、杉原数美、加藤善久、浦丸直人、藤本成明、北村繁幸、太田茂
- Organizer
  環境ホルモン学会第12回研究発表会、講演要旨集(p.124)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] PCB水酸化体(4-OH-CB187)投与による雄性マウスでの腎重量の増加2009
- Author(s)
  内山智晴、関本征史、加藤善久、原口浩一、山田景太、根本清光、出川雅邦
- Organizer
  日本病院薬剤師会東海ブロック日本薬学会東海支部合同学術大会2009、講演要旨集(p.100)
- Place of Presentation
  三重
- Year and Date
  2009-11-23
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] 海綿由来フェノール性臭素化合物の細菌増殖抑制効果:抗菌薬の開発をめざして、フォーラム2009
- Author(s)
  松原大、加藤善久、尾熊隆嘉、小瀧裕一、遠藤哲也、太田千穂、古賀信幸、原口浩一
- Organizer
  衛生薬学・環境トキシコロジー
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-19310042
[Presentation] APCI-LC/MS/MSによる臭素系汚染物質、polybrominated diphenyl ethers(PBDEs)、methoxy PBDEs、hydroxy(OH-)PBDEsの同時定量法の確立:サメ肝臓よりOH-PBDEsを検出2009
- Author(s)
  加藤善久
- Organizer
  第36回日本トキシコロジー学会学術年会
- Place of Presentation
  盛岡
- Year and Date
  2009-07-07
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] 海綿に生息する細菌の16S rRNA遺伝子解析による系統分類2009
- Author(s)
  松原大、大坪仁子、平川裕子、立石大樹、吉浜麻生、剣持直哉、加藤善久、遠藤哲也、原口浩一
- Organizer
  日本薬学会第128年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19310042
[Presentation] 4-OH-2,2',3,4',5,5',6-heptachlorobiphenylによる血中甲状腺ホルモン濃度の低下作用機構の解明2009
- Author(s)
  加藤善久、原口浩一、久保田万紀子、古賀信幸、山田静雄、出川雅邦
- Organizer
  第36回日本トキシコロジー学会学術年会、講演要旨集、J.Toxicol.Sci.(34 Supp. S104)
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] APCI-LC/MS/MS による天然のポリ臭素化ジフェニルエーテル関連化合物の探索:海綿抽出物から創薬への応用を目指して2009
- Author(s)
  岡田将平、加藤善久、跡部一孝、松原大、遠藤哲也、尾熊隆嘉、原口浩一
- Organizer
  第48回日本薬学会・日本薬剤師会日本病院薬剤師会中四国支部学術大会、講演要旨集(p.189)
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] 2,2',3,4,4',5,5'-七塩素化ビフェニル(PCB180)の動物肝ミクロゾームによるin vitro代謝2009
- Author(s)
  太田千穂、原口浩一、加藤善久、遠藤哲也、古賀信幸
- Organizer
  フォーラム2009:衛生薬学・環境トキシコロジー、講演要旨集(p.306)
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] 六塩素化ビフェニルのヒト肝ミクロゾームによる代謝2009
- Author(s)
  太田千穂、原口浩一、加藤善久、遠藤哲也、枩岡樹子、古賀信幸
- Organizer
  日本薬学会第129年会、講演要旨集3(p.247)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] 2,2',3,4',5',6-六塩素化ビフェニル(PCB149)の動物肝ミクロゾームによる代謝2008
- Author(s)
  太田千穂、原口浩一、加藤善久、遠藤哲也、古賀信幸
- Organizer
  フォーラム2008:衛生薬学・環境トキシコロジー、講演要旨集(p.244)
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] Thyroxinemetabolizing rat UDP-glucuronosyltransferase 1A7 is regulated by thyroid hormone receptor.2008
- Author(s)
  Yoshikazu Emi, Shin-ichi Ikushiro, Yoshihisa Kato
- Organizer
  The 12th International Glucuronidation and UGT Workshop, Abstract p.90
- Place of Presentation
  Quebec.
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] APCI-LC/MS/MSによる天然ハロゲン化合物の定量 : 海洋哺乳動物における蓄積特性2008
- Author(s)
  加藤善久
- Organizer
  環境ホルモン学会(第11回研究発表会)
- Place of Presentation
  東京
- Year and Date
  2008-12-14
- Data Source
  KAKENHI-PROJECT-19310042
[Presentation] GC/MS-EI/SIM による天然ハロゲン化合物の定量:サメにおける蓄積特性2008
- Author(s)
  久道洋輔、遠藤哲也、加藤善久、太田千穂、古賀信幸、原口浩一
- Organizer
  フォーラム2008:衛生薬学・環境トキシコロジー、講演要旨集(p.290)
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] APCI-LC/MS/MS による天然ハロゲン化合物の定量:海洋哺乳動物における蓄積特性2008
- Author(s)
  加藤善久、岡田将平、跡部一孝、松原大、遠藤哲也、尾熊隆嘉、原口浩一
- Organizer
  第11回環境ホルモン学会研究発表会、講演要旨集(p.69)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] Metabolism of 2,2',3,4',5,5'-hexachlorobiphenyl (CB146) by liver microsomes from rats, hamsters and guinea pigs.2008
- Author(s)
  Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo, Mikiko Matsuoka, Nobuyuki Koga
- Organizer
  28th International Symposium on Halogenated Persistent Organic Pollutants, Organohalogen Compounds(70 1185-1188)
- Place of Presentation
  Birmingham, UK.
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] 母乳中に残留する天然有機ハロゲン化合物の環境起源調査2008
- Author(s)
  原口浩一、西村恵理、久道洋輔、遠藤哲也、太田千穂、古賀信幸、加藤善久
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19310042
[Presentation] 2,2',4,5,5'-五塩素化ビフェニル(PCB101)のラット、ハムスター、モルモットおよびヒト肝ミクロゾームによる代謝2008
- Author(s)
  太田千穂、原口浩一、加藤善久、枩岡樹子、遠藤哲也、古賀信幸
- Organizer
  第128年会日本薬学会、講演要旨集3(p.181)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] APCI- LC/MS/MSによる天然ハロゲン化合物の定量:海洋哺乳動物における蓄積特性2008
- Author(s)
  加藤善久、岡田将平、跡部一孝、松原大、遠藤哲也、尾熊隆嘉、原口浩一
- Organizer
  環境ホルモン学会第11回研究発表会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19310042
[Presentation] A possible mechanism for the decrease in serum thyroxine level by 4-OH-2, 2', 3, 4', 5, 5', 6-heptachlorobiphenyl in mice.2008
- Author(s)
  Yoshihisa Kato
- Organizer
  28th International Symposium on Halogenated Persistent Organic Pollutants
- Place of Presentation
  Birmingham
- Year and Date
  2008-08-19
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] 母乳中に残留する天然有機ハロゲン化合物の環境起源調査2008
- Author(s)
  原口浩一、西村恵理、久道洋輔、遠藤哲也、太田千穂、古賀信幸、加藤善久
- Organizer
  第128年会日本薬学会、講演要旨集3(p.175)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] APCI-LC/MS/MSによる天然ハロゲン化合物の定量 : 海洋哺乳動物における蓄積特性2008
- Author(s)
  加藤善久
- Organizer
  第11回環境ホルモン学会研究発表会
- Place of Presentation
  東京
- Year and Date
  2008-12-14
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] GC/MS-EI/SIMによる天然ハロゲン化合物の定量:サメにおける蓄積特性、フォーラム2008
- Author(s)
  久道洋輔、遠藤哲也、加藤善久、太田千穂、古賀信幸、原口浩一
- Organizer
  衛生薬学・環境トキシコロジー
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-19310042
[Presentation] A possible mechanism for the decrease in serum thyroxine level by 4-OH-2,2',3,4',5,5',6-heptachlorobiphenyl in mice.2008
- Author(s)
  Yoshihisa Kato, Koichi Haraguchi, Makiko Kubota, Shin-ichi Ikushiro, Toshiyuki Sakaki, Nobuyuki Koga, Shizuo Yamada, Masakuni Degawa
- Organizer
  28th International Symposium on Halogenated Persistent Organic Pollutants, Organohalogen Compounds(70 1601-1604)
- Place of Presentation
  Birmingham, UK.
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] 海洋哺乳動物におけるPCB代謝物:鯨類の肝臓中にみられるmethylsulfoneおよびdihydorxy体の残留特性2008
- Author(s)
  原口浩一、久道洋輔、遠藤哲也、加藤善久、太田千穂、古賀信幸
- Organizer
  フォーラム2008:衛生薬学・環境トキシコロジー、講演要旨集(p.291)
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20510070
[Presentation] 4-OH-2,2',3,4',5,5',6-heptachlorobiphenylの血中甲状腺ホルモン濃度におよぼす影響2006
- Author(s)
  加藤善久
- Organizer
  第33回日本トキシコロジー学会学術年会, J.Toxicol.Sci., (31Supple.), S221
- Place of Presentation
  名古屋
- Year and Date
  2006-07-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18510061
[Presentation] Hexabromocyclododecanes, tribromophenol and tetrabromobisphenol A in Japanese breast milk
- Author(s)
  Haraguchi, Koichi; Fujii, Yukiko; Kato, Yoshihisa
- Organizer
  Society of Toxicology 54th Annual Meeting
- Place of Presentation
  San Diego, California
- Year and Date
  2015-03-22 – 2015-03-26
- Data Source
  KAKENHI-PROJECT-24310049
[Presentation] 海洋生物由来のTetrabromo-1,4-dimethoxybenzene(TDB)の動物肝ミクロゾームによる代謝
- Author(s)
  太田千穂、西村理恵、原口浩一、遠藤哲也、加藤善久、山元健太、古賀信幸
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24310049
[Presentation] 海洋生物由来のtetrabromoveratrole(TBV)の動物肝ミクロゾームによる代謝
- Author(s)
  太田千穂、西村恵理、原口浩一、遠藤哲也、加藤善久、山本健太、古賀信幸
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本市中央区）
- Data Source
  KAKENHI-PROJECT-24310049
[Presentation] Kaempferol tetramethyleherのラット肝ミクロゾームによる代謝
- Author(s)
  山本健太，緒方瞳，太田千穂，原口浩一，遠藤哲也，西村恵理，木村修，加藤善久，古賀信幸
- Organizer
  第68回日本栄養・食糧学会大会
- Place of Presentation
  江別
- Year and Date
  2014-05-30 – 2014-06-01
- Data Source
  KAKENHI-PROJECT-23510083
[Presentation] Contamination trends of hexabromocyclododecanes, tribromophenol and tetrabromobisphenol a in Japanese breast milk
- Author(s)
  Koichi Haraguchi, Yukiko Fujii, Yoshihisa Kato, Tetsuya Endo
- Organizer
  54th The exposition of the Society of Toxicology Annual Meeting
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2015-03-22 – 2015-03-25
- Data Source
  KAKENHI-PROJECT-23510083
[Presentation] 海洋生物由来2,2'-dimethoxy-BB80のラットにおけるin vivo代謝
- Author(s)
  西村恵理，太田千穂，原口浩一，遠藤哲也，加藤善久，山本健太，古賀信幸
- Organizer
  フォーラム2014：衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] The participation of rat CYP3A enzymes in the metabolism of 2,2',4,5,5'-pentachlorobiphenyl (CB101)
- Author(s)
  Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo, Nobuyuki Koga
- Organizer
  34th International Symposium on Halogenated Persistent Organic Pollutants
- Place of Presentation
  Madrid, Spain
- Year and Date
  2014-08-31 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-23510083
[Presentation] Contamination trends of hexabromocyclododecanes, tribromophenol and tetrabromobisphenol a in Japanese breast milk
- Author(s)
  Koichi Haraguchi, Yukiko Fujii, Yoshihisa Kato, Tetsuya Endo
- Organizer
  54th The exposition of the Society of Toxicology Annual Meeting
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2015-03-22 – 2015-03-26
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] The participation of rat CYP3A enzymes in the metabolism of 2,2',4,5,5'-pentachlorobiphenyl (CB101)
- Author(s)
  Chiho Ohta, Koichi Haraguchi, Yoshihisa Kato, Tetsuya Endo, Nobuyuki Koga
- Organizer
  34th International Symposium on Halogenated Persistent Organic Pollutants
- Place of Presentation
  Madrid, Spain
- Year and Date
  2014-08-31 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] 海洋生物由来のTetrabromo-1,4-dimethoxybenzene (TDB)の動物肝ミクロゾームによる代謝
- Author(s)
  太田千穂，西村恵理，原口浩一，遠藤哲也，加藤善久，山本健太，古賀信幸
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] 海洋生物由来2,2'-dimethoxy-BB80のラットにおけるin vivo代謝
- Author(s)
  西村恵理，太田千穂，原口浩一，遠藤哲也，加藤善久，山本健太，古賀信幸
- Organizer
  フォーラム2014：衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-23510083
[Presentation] 海洋生物由来2,2’-dimethoxy-BB80のラットにおけるin vivo代謝
- Author(s)
  西村恵理、太田千穂、原口浩一、遠藤哲也、加藤善久、山本健太、古賀信幸
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-24310049
[Presentation] Kaempferol tetramethyleherのラット肝ミクロゾームによる代謝
- Author(s)
  山本健太，緒方瞳，太田千穂，原口浩一，遠藤哲也，西村恵理，木村修，加藤善久，古賀信幸
- Organizer
  第68回日本栄養・食糧学会大会
- Place of Presentation
  江別
- Year and Date
  2014-05-30 – 2014-06-01
- Data Source
  KAKENHI-PROJECT-26340043
[Presentation] 海洋生物由来のTetrabromo-1,4-dimethoxybenzene (TDB)の動物肝ミクロゾームによる代謝
- Author(s)
  太田千穂，西村恵理，原口浩一，遠藤哲也，加藤善久，山本健太，古賀信幸
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-23510083

1. HARAGUCHI Koichi (00258500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 33 results
2. OGUMA Takatoshi (20446074)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. MATSUBARA Futoshi (60368975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. NISHIMURA Eri (80412550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. ATOBE Kazutaka (00454885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KOGA Nobuyuki (80136514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
7. ENDO Tetsuya (10133216)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
8. OHTA Chiho (80271435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
9. KIMURA Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. SUEMARU Katsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. ARAKI Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. HARADA Kouji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 藤井由希子

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
14. 小泉昭夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KATO Yoshihisa 加藤 善久

加藤 善久 カトウ ヨシヒサ

Research Projects

Research Products

Co-Researchers

PCBなどの化学物質の甲状腺ホルモン濃度低下作用発現メカニズムの全容解明Principal Investigator

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Study on the possible mechanism for the polychlorinated biphenyl-induced liver-selective accumulation of thyroxinePrincipal Investigator

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Metabolic activation of naturally porduced halogenated compounds in human

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Study on the exact mechanism for the polychlorinated biphenyl-induced decrease in the serum thyroxine levelPrincipal Investigator

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A novel mechanism for polychlorinated biphenyl-induced decrease in serum thyroxine levelPrincipal Investigator

Principal Investigator

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Research of antibacterial chemicals in marine sponge and development of lead compounds for therapy in infectious diseases

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Development of liposome for treatment of multidrug-resistant cancer

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A possible mechanism for decrease in serum thyroxine level by polychlorinated biphenylsPrincipal Investigator

Principal Investigator

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Research Institution

Species differences among mice, hamsters, rats and guinea pigs in PCB-induced alteration of serum thyroid hormone levelPrincipal Investigator

Principal Investigator

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Methylsulfonyl metabolites of polychlorinated biphenyl and polybrominated biphenyl as disrupters of endocrine actionPrincipal Investigator

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Research Institution

The role of 3-methylsulfony (3-MeSOィイD22ィエD2) metabolites in the induction of hepatic microsomal drug-metabolizing enzymes by PCB congeners, and the toxicological effects of the MeSOィイD22ィエD2 metabolites of PCB congenersPrincipal Investigator

Principal Investigator

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Research Institution

[Book] Persistent Organic Pollutants (POPs) Research in Asia(Edited by Masatoshi Morita)(The formation of a catechol metabolite of 2,2',4,5,5'-pentachlorobiphenyl (CB101) by liver microsomes from rats, hamsters, guinea pigs and humans.)2008

Author(s)

Publisher

Data Source

[Book] Persistent Organic Pollutants (POPs) Research in Asia(Edited by Masatoshi Morita)(The distribution of metabolites of 2,2',3,4,4',5',6-heptachlorobiphenyl (CB183) in rats and guinea pigs.)2008

Author(s)

Publisher

Data Source

[Book] 甲状腺ホルモン撹乱物質の生体作用の動物種差.生体統御システムと内分泌撹乱2005

KATO Yoshihisa 加藤善久

加藤善久カトウヨシヒサ