HOTTA Kunimoto 堀田国元

… Alternative Names

堀田国元ホツタクニモト

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Researcher Number	90165564
External Links
Affiliation (based on the past Project Information) *help	2000: National Institute of Infectious Diseases, Department of Bioactive Molecules, Laboratory Head, 生物活性物質部, 厚生技官 1999 – 2000: 国立感染症研究所, 生物活性物質部・室長(厚生技官) 1992: 国立予防衛生研究所, 生物活性物質部, 室長 1990 – 1991: 国立予防衛生研究所, 抗生物質部, 室長
Review Section/Research Field	Principal Investigator Bioorganic chemistry Except Principal Investigator Experimental pathology
Keywords	Principal Investigator AAC(6') / AAC(2') / AAC(3) / Doble stage activity / diacetylation / Aminoglycoside antibiotics / APH(2'') / Antibiotic resistance gene / 活性アセチル化アミノグリコシド / ジアセチル化 / アミノグリコシド抗生物質 / APH(2") / 薬剤耐性遺伝子 … More Except Principal Investigator … More 蛋白質りん酸化 / 血管内皮細胞 / 癌細胞培養液 / O_2ー産生 / 酵素放出 / 多型核白血球 / PCR / リコンビナント / サイトカイン / モノクロナル抗体 / 自己免疫疾患 / インタ-ロイキン8 / l-plastin / p64 / 細胞骨格 / キナーゼ / 細胞情報伝達機構 / 骨髄性白血病細胞ML-1 / 多形核白血球 / 好中球 / 走化性因子 / LUCT-インターロイキン8 Less

Basic researches for the development of novel antibiotics with double stage activityPrincipal Investigator
- Principal Investigator
  
  HOTTA Kunimoto
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  National Institute of Infectious Diseases
がん細胞由来白血球走化性蛋白質LUCTの情報伝達機構とその発現に関する研究
- Principal Investigator
  
  鈴木和男
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  国立予防衛生研究所

All 2000 1999

All Journal Article

[Journal Article] コロニーPCR法によるMRSAおよび腸球菌の薬剤耐性遺伝子の迅速検出2000
- Author(s)
  土崎尚史, 石川淳, 堀田国元
- Journal Title
  
  Japanese J.Antibiotics 53・6
  
  Pages: 422-429
- NAID
  130004131017
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11680599
[Journal Article] Colony PCR for detection of specific DNA sequences in actinomysetes2000
- Author(s)
  J.Ishikawa, N.Tsuchizaki, M.Yoshida, D.Ishiyama, K.Hotta
- Journal Title
  
  Actinomycetologica 14・1
  
  Pages: 1-5
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11680599
[Journal Article] Acetylation of aminoglycoside antibiotics with 6'-methylamino group, Istamycin B and micronomicin, by a novel aminoglycoside 6'-acetyltransferase of actinomycete origin.2000
- Author(s)
  Sunada A, Ikeda Y, Kondo S, Hotta K
- Journal Title
  
  J.Antibiotics 53(12)
  
  Pages: 1416-1419
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11680599
[Journal Article] Identification and characterization of the point mutation which affects the transcription level of the chromosomal 3-N-acetyltransferase gene of Streptomyces griseus SS-1198.2000
- Author(s)
  Ishikawa J, Sunada A, Oyama R, Hotta A
- Journal Title
  
  Antimicrob. Agents and Chemother. 44
  
  Pages: 437-440
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11680599
[Journal Article] Double stage activity in aminoglycoside antibiotics2000
- Author(s)
  K.Hotta, A.Sunada, Y.Ikeda, S.Kondo
- Journal Title
  
  J.Antibiotics 53・10
  
  Pages: 1168-1174
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11680599
[Journal Article] Colony PCR for detection of specific DNA sequences in actinomysetes.2000
- Author(s)
  Ishikawa J, Tsuchizaki N, Yoshida M, Ishiyama D, Hotta K
- Journal Title
  
  Antinomycetologica 14(1)
  
  Pages: 1-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11680599
[Journal Article] Acetylation of aminoglycoside antibiotics with 6'-methyl-amino group, Istamycin B and micronomicin, by a novel aminoglycoside 6'-acetyltransferase of actinomycete origin2000
- Author(s)
  A.Sunada, Y.Ikeda, S.Kondo, K.Hotta
- Journal Title
  
  J.Antibiotics 53・12
  
  Pages: 1416-1419
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11680599
[Journal Article] Colony PCR for rapid detection of antibiotic resistance genes in MRSA and Enterococci.2000
- Author(s)
  Tsuchizaki N, Ishikawa J, Hotta K
- Journal Title
  
  Japanese J. Antibiotics 53(6)
  
  Pages: 422-429
- NAID
  10005888267
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11680599
[Journal Article] Double stage activity in aminoglycoside antibiotics.2000
- Author(s)
  Hotta K, Sunada A, Ikeda Y, Kondo S
- Journal Title
  
  J.Antibiotics 53(10)
  
  Pages: 1168-1174
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11680599
[Journal Article] Identification and characterization of the point mutation which affects the transcription level of the chromosomal 3-N-acetyltransferase gene of Streptomyces griseus SS-1198.2000
- Author(s)
  Ishikawa J, Sunada A, Oyama R, K.Hotta
- Journal Title
  
  Antimicrob.Agents and Chemother. 44・2
  
  Pages: 437-440
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11680599
[Journal Article] Enzymatic 1-N-Acetylation of paromomyin by an actinomycete strain #8 with multiple aminoglycoside resistance and paromomycin sensitivity.1999
- Author(s)
  Sunada A, Nakajima M, Ikeda Y, Kondo S, Hotta K
- Journal Title
  
  J.Antibiotics 52(9)
  
  Pages: 809-814
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11680599
[Journal Article] Role of aminoglycoside 6'-acetyltransferase in a novel multiple aminoglycoside resistance of an actinomycete strain #8 : isolation of aminoglycosides with 6'-amino group except arbekacin and neomycin.1999
- Author(s)
  Zhu CB, Sunada A, Ishikawa J, Ikeda Y, Kondo S, Hotta K
- Journal Title
  
  J.Antibiotics 52・10
  
  Pages: 889-894
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11680599
[Journal Article] Role of aminoglycoside 6'-acetyltransferase in a novel multiple aminoglycoside resistance of an actinomycete strain #8: isolation of aminoglycosides with 6'-amino group except arbekacin and neomycin.1999
- Author(s)
  Zhu CB, Sunada A, Ishikawa J, Ikeda Y, Kondo S, Hotta K
- Journal Title
  
  J.Antibiotics 52(10)
  
  Pages: 889-894
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11680599
[Journal Article] Enzymatic 1-N-Acetylation of paromomyin by an actinomycete strain #8 with multiple aminoglycoside resistance and paromomycin sensitivity.1999
- Author(s)
  Sunada A, Nakajima M, Ikeda Y, Kondo S, Hotta K
- Journal Title
  
  J.Antibiotics 52・9
  
  Pages: 809-814
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11680599

1. ISHIKAWA Jun (40202957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. 鈴木和男 (20192130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 水野左敏 (60072930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HOTTA Kunimoto 堀田 国元

堀田 国元 ホツタ クニモト

Research Projects

Research Products

Co-Researchers

Basic researches for the development of novel antibiotics with double stage activityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

がん細胞由来白血球走化性蛋白質LUCTの情報伝達機構とその発現に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] コロニーPCR法によるMRSAおよび腸球菌の薬剤耐性遺伝子の迅速検出2000

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Colony PCR for detection of specific DNA sequences in actinomysetes2000

Author(s)

Journal Title

Description

Data Source

[Journal Article] Acetylation of aminoglycoside antibiotics with 6'-methylamino group, Istamycin B and micronomicin, by a novel aminoglycoside 6'-acetyltransferase of actinomycete origin.2000

Author(s)

Journal Title

Description

Data Source

[Journal Article] Identification and characterization of the point mutation which affects the transcription level of the chromosomal 3-N-acetyltransferase gene of Streptomyces griseus SS-1198.2000

Author(s)

Journal Title

Description

Data Source

[Journal Article] Double stage activity in aminoglycoside antibiotics2000

Author(s)

Journal Title

Description

Data Source

[Journal Article] Colony PCR for detection of specific DNA sequences in actinomysetes.2000

Author(s)

Journal Title

Description

Data Source

[Journal Article] Acetylation of aminoglycoside antibiotics with 6'-methyl-amino group, Istamycin B and micronomicin, by a novel aminoglycoside 6'-acetyltransferase of actinomycete origin2000

Author(s)

Journal Title

Description

Data Source

[Journal Article] Colony PCR for rapid detection of antibiotic resistance genes in MRSA and Enterococci.2000

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Double stage activity in aminoglycoside antibiotics.2000

Author(s)

Journal Title

Description

Data Source

[Journal Article] Identification and characterization of the point mutation which affects the transcription level of the chromosomal 3-N-acetyltransferase gene of Streptomyces griseus SS-1198.2000

Author(s)

Journal Title

Description

Data Source

[Journal Article] Enzymatic 1-N-Acetylation of paromomyin by an actinomycete strain #8 with multiple aminoglycoside resistance and paromomycin sensitivity.1999

Author(s)

Journal Title

Description

Data Source

[Journal Article] Role of aminoglycoside 6'-acetyltransferase in a novel multiple aminoglycoside resistance of an actinomycete strain #8 : isolation of aminoglycosides with 6'-amino group except arbekacin and neomycin.1999

Author(s)

Journal Title

Description

Data Source

[Journal Article] Role of aminoglycoside 6'-acetyltransferase in a novel multiple aminoglycoside resistance of an actinomycete strain #8: isolation of aminoglycosides with 6'-amino group except arbekacin and neomycin.1999

HOTTA Kunimoto 堀田国元

堀田国元ホツタクニモト