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SHIMIZU Katsuji
清水 克時
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Alternative Names
清水 克時 シミズ カツジ
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Researcher Number
90170969
Other IDs
External Links
Affiliation (based on the past Project Information)
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2013: 岐阜大学, 大学院医学研究科, 教授
2011 – 2013: 岐阜大学, 医学(系)研究科(研究院), 教授
2008: 岐阜大学, 大学院・医学研究科, 教授
2007 – 2008: 岐阜大学, 大学院・医学系研究科, 教授
2006: 岐阜大学, 大学院医学系研究科, 教授
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1998 – 2003: 岐阜大学, 医学部, 教授
1995: 京都大学, 医学研究科, 助教授
1991 – 1994: 京都大学, 医学部, 講師
1988: Faculty of Medicine, Kyoto University, 医学部, 助手
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Review Section/Research Field
Principal Investigator
Orthopaedic surgery
Except Principal Investigator
Orthopaedic surgery
/
Orthopaedic surgery
Keywords
Principal Investigator
カルパイン / マトリックス分解酵素 / カルパスタチン / 関節炎 / CALPAIN / カルパイン(calpain) / 骨折(fracture) / 仮骨(callus) / プロテオグリカン(proteoglycan) / コラーゲン誘発関節炎
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/ マウス / 滑膜 / 軟骨破壊 / 関節液 / calpain / calpastatin / activitis / synovia / matrix proteinase / cartilage degradation / 化学的髄核融解 chemonucleolysis / カルパイン calpain / 脳脊髄液 cerebrospinal fluild / 脳脊髄液 cerebrospinal fluid / 化学的髄核融解 / CHEMONUCLEOLYSIS / CEREBROSPINAL FLUID / 慢性関節リウマチ / 滑膜細胞 / アポトーシス / p53 / calpain(カルパイン) / apoptosis(アポトーシス) / signal transduction(シグナル伝達) / rheumatoid arthritis / synovial cells / apoptosis / P53 / 関節軟骨 / プロテオグリカン / モノクローナル / アグリカン / CARTILAGE / PROTEOGLYCAN / ARTHRITIS / 椎間板 / 老化 / アミロイド / Intervertebral Discs / Ageing
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Except Principal Investigator
カルパイン / プロテオグリカン / calpain / 椎間板 / TNF-α / 内軟骨性骨化 / 骨形成 / カルパスタチン / カルシウム / 関節血腫 / 軟骨破壊 / 膝関節 / ラット / 単核球 / 脊椎脊髄病学 / 骨・軟骨代謝学 / 生体関連物質 / 加齢医学 / 病態モデル / intervertebral disc / degeneration / anti aging / spine / yelolow ligament / anti-aging / yellow ligament / アンチエイジング / 変性 / 炎症 / サイトカイン / 脊椎 / ３次元培養 / 3次元培養 / カルパインI / 化学的髄核融解 / Chemonucleolysis / プロテオグリャン / calpain I / calpastatin / chemonucleolysis / 軟骨細胞 / 非ステロイド抗炎症剤 / 関節炎 / chondrocyte / NSAIDs / arthritis
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Research Projects
(
13
results)
Research Products
(
2
results)
Co-Researchers
(
12
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Development of New Biological Therapy for Regeneration of Degenerated Interbvertebral Discs
Principal Investigator
MIYAMOTO Kei
Project Period (FY)
2011 – 2013
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Orthopaedic surgery
Research Institution
Gifu University
Disc regeneration aiming at suppression of inflammatory cytokines
Principal Investigator
MIYAMOTO Kei
Project Period (FY)
2006 – 2008
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Orthopaedic surgery
Research Institution
Gifu University
PRODUCTION OF SPECIFIC MONOCLONAL ANTIBODY FOR CALPAIN CLEAVAGE SITES AND CLINICAL APPLICATION
Principal Investigator
Principal Investigator
SHIMIZU Katsuji
Project Period (FY)
2002 – 2003
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Orthopaedic surgery
Research Institution
GIFU UNIVERSITY
The expression of m-calpain in human synovial fibroblasts and chondrocytes.
Principal Investigator
ITOH Yoshiki
Project Period (FY)
2002 – 2003
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Orthopaedic surgery
Research Institution
Gifu University School of Medicine
Expression of calpain on apoptosis signaling in human rheumatoid synovial cells
Principal Investigator
Principal Investigator
SHIMIZU Katsuji
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Orthopaedic surgery
Research Institution
GIFU UNIVERSITY
TREATMENT OF HERNIATED INTERVERTEBRAL DISCS WITH AUTOGENOUS CALPAIN PURIFIED FROM PATIENT'S OWN RED BLOOD CELLS
Principal Investigator
Principal Investigator
SHIMIZU Katsuji
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Orthopaedic surgery
Research Institution
Gifu University
成長軟骨骨化におけるカルパインの役割
Principal Investigator
井戸 一博
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Orthopaedic surgery
Research Institution
Kyoto University
実験的関節血腫における軟骨プロテオグリカンの破壊
Principal Investigator
飯田 寛和
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Orthopaedic surgery
Research Institution
Kyoto University
コラーゲン誘発マウス関節炎におけるカルパイン
Principal Investigator
Principal Investigator
清水 克時
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Orthopaedic surgery
Research Institution
Kyoto University
Calpain of Synovia and synovial fluid in arthritis
Principal Investigator
Principal Investigator
SHIMIZU Katsuji
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Orthopaedic surgery
Research Institution
KYOTO UNIVERSITY
Chemonucleolysis with calpaine I in Rabbits
Principal Investigator
YAMAMURO Takao
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Orthopaedic surgery
Research Institution
KYOTO UNIVERSITY
骨折治癒過程におけるカルシウム依存性プロテア-ゼ(calpain)
Principal Investigator
Principal Investigator
清水 克時
Project Period (FY)
1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Orthopaedic surgery
Research Institution
Kyoto University
Biochemical Investigation on Amyloid of Ageing in Human Intervertebral Discs.
Principal Investigator
Principal Investigator
SHIMIZU Katsuji
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Orthopaedic surgery
Research Institution
Kyoto University
All
2012
All
Journal Article
Presentation
[Journal Article] ヒト椎間板変性におけるカルパインの影響
2012
Author(s)
福田章二,宮本敬,鈴木毅一,井上俊之,喜久生健太,清水克時
Journal Title
中部日本整形外科・災害外科学会雑誌
Volume
: Vol.55No.5
Pages
: 94-94
Data Source
KAKENHI-PROJECT-23592162
[Presentation] ヒト椎間板におけるカルパインの局在と働き
2012
Author(s)
福田章二，宮本敬，井上俊之，鈴木毅一，喜久生健太，清水克時
Organizer
第１１８回 中部整形外科災害外科学会
Place of Presentation
大阪市
Data Source
KAKENHI-PROJECT-23592162
# of Projects (Dsc)
# of Projects (Asc)
1.
ITOH Yoshiki
(10313884)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
2.
MIYAMOTO Kei
(20313885)
# of Collaborated Projects:
2 results
# of Collaborated Products:
2 results
3.
井戸 一博
(70252442)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
4.
YAMAMURO Takao
(00088527)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
5.
NAKAYAMA Yuichiro
(40243026)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
6.
SAKAGUCHI Yasumichi
(60301214)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
7.
HOSOE Hideo
(60219186)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
IWASAKI Renpei
(70184877)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
松下 睦
(50229473)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
飯田 寛和
(60176047)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
KYUUKI Kouhei
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
西本 博文
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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