TSURUSAWA Masahito 鶴澤正仁

Researcher Number	90172064
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2015: 愛知医科大学, 医学部, 教授 2013 – 2015: 愛知医科大学, 医学部, 名誉教授 2010 – 2012: 愛知医科大学, 医学部, 教授 2002: Aichi Medical University, Department of Pediatrics Professor, 教授 2001 – 2002: 愛知医科大学, 医学部, 教授 … More 2001: 愛知医学大学, 教授 1997 – 2000: 愛知医科大学, 医学部, 助教授 1986 – 1987: 愛知医科大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Pediatrics / Hematology / Laboratory medicine
Keywords	Principal Investigator RQ-PCR / MRD / ALL / 小児急性白血病 / 再発白血病 / 免疫関連遺伝子再構成 / 微小残存病変 / 小児白血病 Except Principal Investigator IL-4 / minimal residual disease … More / Flow cytometry / IFN-γ / MRD monitoring / ATRA-resistance / mutant PML-RARa / RARa / PML / all-trans retinoic acid / Acute promyelocytic leukemia / Atopic dermatitis / Food hypersensitivity / フローサイトメトリー / アトピー性皮膚炎 / 食物アレルギー / ALLのPhenotyping / 小児期急性白血病の細胞heterogeneity / 免疫学的phenotype / DNA aneuploidy / 小児造血器腫瘍のHetergeneity / immunoglobulin chaingene / T-cell receptor gene / chemotherapy / childhood leukemia / acute lymphoblastic leukemia / PCR / 免疫グロブリン遺伝子 / 微小残存病変 / 免疫グロブル遺伝子 / T細胞受容体遺伝子 / 化学療法 / 小児白血病 / 急性リンパ性白血病 / 微小残有病変 / レチノール酸耐性 / 定量PCR / MRDモニタリング / 急性前骨髄性白血病 / mutantPML / Acute promelocytic leukemia / MRD minitoring / mutant PML / acute promyelocytic leukemia / IFN-_γ / IFN-gamma / Lymphocyte proliferation / 細胞内サイトカイン / 小児アレルギー / リンパ球幼若化反応 / リンパ球増殖反応 / 選択的毒性 / 国際情報交換 / アミノ酸代謝 / 感受性予測 / 酵素製剤 / 細胞死 / 抗がん剤 / 選択毒性 / アミノ酸要求性 / 分子標的療法 Less

Development of a predictive system of the sensitivity for L-asparaginase in tumor by monoclonal antibody
- Principal Investigator
  
  Kitoh Toshiyuki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Aichi Medical University
STUDY OF MINIMAL RESIDUAL DISEASE MEASUREMENTS AND CLINICAL APPLICATION IN PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIAPrincipal Investigator
- Principal Investigator
  
  TSURUSAWA Masahito
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Aichi Medical University
Study on mechanism of ATRA-resistance and utility of MRD-monitoring in acute promyelocytic leukemia
- Principal Investigator
  
  IMAIZUMI Masue
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
A clinical study of MRD-based therapy for childhood ALL
- Principal Investigator
  
  YOKOYA Shohei
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine
Cytokines production in food-allergen reactive-lymphocytes in food hypersensitivity
- Principal Investigator
  
  AGATA Hiroatsu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Aichi Medical University
Organ selectivity in food-allergen reactive-lymphocytes in food hypersensitivity
- Principal Investigator
  
  AGATA Hiroatsu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Aichi Medical University
Studies on Pathobiology and Heterogeneity of Childhood Hematologic Malignancies
- Principal Investigator
  
  FUJIMOTO Takeo
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Aichi Medical University

All 2013 2012 2011 2010 Other

All Journal Article Presentation Book Patent

[Book] 小児造血器腫瘍の診断の手引き2012
- Author(s)
  堀壽成,堀部敬三,鶴澤正仁編
- Publisher
  東京:日本医学館
- Data Source
  KAKENHI-PROJECT-22591170
[Book] 小児白血病リンパ腫の診療ガイドライン2011
- Author(s)
  鶴澤正仁
- Total Pages
  123
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-22591170
[Book] 小児ALL治療でのMRD測定の役割は何か
- Author(s)
  鶴澤正仁
- Publisher
  「小児白血病リンパ腫の診療ガイドライン2011年版」編集責任者・日本小児血液学会編金原出版
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] THE THERAPEUTIC VALUE OF ASPARAGINE SYNTHETASE DEFICIENCY IN LANGERHANS CELL HISTIOCYTOSIS.2013
- Author(s)
  Kitoh Toshiyuki, Shimomura Yasuto, Hori Toshinari, Terashima Tsuyoshi, Yokoi Toyoharu, Tsurusawa Masahito.
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590713
[Journal Article] 微小残存腫瘍量測定とその意義2012
- Author(s)
  鶴澤正仁
- Journal Title
  
  日本臨床
  
  Volume: 70 Pages: 731-736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] 微小残存腫瘍量測定とその意義2012
- Author(s)
  鶴澤正仁、堀壽
- Journal Title
  
  日本臨床.
  
  Volume: 70巻別冊2号 Pages: 731-736
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] Continuous and high-dose cytarabine combined chemotherapy in children with down syndrome and acute myeloid leukemia : Report from the Japanese children's cancer and leukemia study group (JCCLSG) AML 9805 down study2011
- Author(s)
  Taga T, Tsurusawa M, et al
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 15 Pages: 36-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] Assessment of late cardiotoxicity of pirarubicin (THP) in children with acute lymphoblastic leukemia2011
- Author(s)
  Shimomura Y, Tsurusawa M, et al
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 57 Pages: 461-466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] Flow cytometric analysis of de novo acute myeloid leukemia in childhood : report from the Japanese Pediatric Leukemia/Lymphoma Study Group2011
- Author(s)
  Ohta H, Tsurusawa M, et al
- Journal Title
  
  Int J Hematol
  
  Volume: 93 Pages: 135-137
- NAID
  10029532850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] Japanese Childhood Cancer and Leukemia Study Group (JCCLSG). Assessment of late cardiotoxicity of pirarubicin (THP) in children with acute lymphoblastic leukemia.2011
- Author(s)
  Shimomura Y, Baba R, Watanabe A, Horikoshi Y, Asami K, Hyakuna N, Iwai A, Matsushita T, Yamaji K, Hori T,Tsurusawa M;
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 57 Pages: 461-466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] 思春期・小児ALLの標準治療と最近の研究動向。2011
- Author(s)
  鶴澤正仁
- Journal Title
  
  臨床血液
  
  Volume: 52巻 Pages: 1585-1593
- NAID
  10029769094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] Flow cytometric analysis of de novo acute lymphoblastic leukemia in childhood : report from the Japanese Pediatric Leukemia/Lymphoma Study Group2011
- Author(s)
  Iwamoto S, Tsurusawa M, et al
- Journal Title
  
  Int J Hematol
  
  Volume: 94 Pages: 185-192
- NAID
  10029537148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] Chromosome abnormalities in advanced stage T-cell lymphoblastic lymphoma of children and adolescents : a report from Japanese Paediatric Leukaemia/Lymphoma Study Group (JPLSG) and review of the literature2011
- Author(s)
  Sekimizu M, Tsurusawa M, et al
- Journal Title
  
  Br J Haematol
  
  Volume: 154 Pages: 612-617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] Flow cytometric analysis of de novo acute lymphoblastic leukemia in childhood: report from the Japanese Pediatric Leukemia/Lymphoma Study Group.2011
- Author(s)
  Iwamoto S, Deguchi T, Ohta H, KiyokawaN, Tsurusawa M, Yamada T, Takase K, Fujimoto J, Hanada R, Hori H, HoribeK, Komada Y.
- Journal Title
  
  Int JHematol
  
  Volume: 94 Pages: 185-192
- NAID
  10029537148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] Distinct impact of imatinib on growth at prepubertal and pubertal ages of children with chronic myeloid leukemia2011
- Author(s)
  Shima H, Tsurusawa M, et al
- Journal Title
  
  J Pediatr
  
  Volume: 159 Pages: 676-681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] Minimal residual disease-based augmented therapy in childhood acute lymphoblastic leukemia : a report from the Japanese Childhood Cancer and Leukemia Study Group.2010
- Author(s)
  Yamaji K, Hori T, Tsurusawa M, et al.
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: VOL.5 Pages: 1287-1205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] Japanese Childhood Cancer Leukemia Study Group. Minimal residualdisease-based augmented therapy in childhood acute lymphoblastic leukemia: a report from the Japanese Childhood Cancer and Leukemia Study Group.2010
- Author(s)
  Yamaji K, Okamoto T, Yokota S, WatanabeA, Horikoshi Y, Asami K, Kikuta A, Hyakuna N, Saikawa Y, Ueyama J, Watanabe T, Okada M, Taga T, Kanegane H, Kogawa K, Chin M, Iwai A, Matsushita T, Shimomura Y, Hori T, Tsurusawa M;
- Journal Title
  
  Pediatr Blood Cancer.
  
  Volume: 55 Pages: 1287-1295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] Long-term results of the Japanese childhood cancer and leukemia study group studies 811, 841, 874, and 911 on childhood acute lymphoblastic leukemia.2010
- Author(s)
  Tsurusawa M, et al.
- Journal Title
  
  Leukemia
  
  Volume: VOL.24 Pages: 335-344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Journal Article] Japanese Childhood Cancer and Leukemia Study Group. Long-term results of the Japanese childhood cancer and leukemia study group studies 811, 841, 874, and 911 onchildhood acute lymphoblastic leukemia.2010
- Author(s)
  Tsurusawa M, Shimomura Y, Asami K, Kikuta A, Watanabe A, Horikoshi Y, Matsushita T, Kanegane H, Ohta S, IwaiA, Mugishima H, Koizumi S;
- Journal Title
  
  Leukemi
  
  Volume: 24 Pages: 335-344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591170
[Patent] アスパラギン合成酵素を特異的に認識するモノクローナル抗体2013
- Inventor(s)
  浜窪隆雄、望月康弘、岩成宏子、新井　修、鬼頭敏幸、鶴澤正仁
- Industrial Property Rights Holder
  浜窪隆雄、望月康弘、岩成宏子、新井　修、鬼頭敏幸、鶴澤正仁
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2011-218966
- Filing Date
  2013-04-09
- Overseas
- Data Source
  KAKENHI-PROJECT-24590713
[Presentation] Flow Cytometric Detection of Asparagine Synthetase Protein in Leukemia Cells; Indication for LAsparaginase Therapy2013
- Author(s)
  Toshiyuki Kitoh, Kou Suchan Gao Siqiang, Hidefumi Kato, Yasuto Shimomura, Toshinori Hori, Kimiyoshi Sakaguchi, Hiroshi Miwa, Masahito Tsurusawa, Takao Hamakubo
- Organizer
  EAP 2013-European Academy of Paediatrics Educational Congress & MasterCourse
- Place of Presentation
  Lyon, France
- Data Source
  KAKENHI-PROJECT-24590713
[Presentation] AGGRESSIVE LANGERHANS CELL HISTIOCYTOSIS FOLLOWING T-ALL: CLONALLY RELATED NEOPLASMS WITHOUT BRAF V600E MUTATION AND SUFFICIENT EXPRESSION OF ASPARAGINE SYNTHETASE2013
- Author(s)
  Kitoh Toshiyuki, Akiyama Masaharu, Taki Tomohiko, Shimomura Yasuto, Hori Toshinari, Terashima Tsuyoshi, Yokoi Toyoharu, Tsurusawa Masahito.
- Organizer
  29th Histiocyte Society Annual Meeting
- Place of Presentation
  Washington, DC. USA
- Data Source
  KAKENHI-PROJECT-24590713
[Presentation] CCLAGALL2004登録症例のPCR-MRD定量におけるnestedPCRとRQ-PCRによる定量値の比較.2012
- Author(s)
  堀壽成,山田朋美,山路和孝,鶴澤正仁,横田昇平,渡辺新,菊田敦,浅見恵子.
- Organizer
  第54回日本小児血液・がん学会学術集会.
- Place of Presentation
  横浜
- Year and Date
  2012-11-30
- Data Source
  KAKENHI-PROJECT-22591170
[Presentation] CCLSGALL2004研究におけるIg/Tc遺伝子再構成のパターンとRQPCR-MRDへの適応性2012
- Author(s)
  堀壽成,山田朋美,山路和孝,横田昇平,渡辺新,菊田敦,浅見恵子.鶴澤正仁。
- Organizer
  第52回日本小児血液学会総会
- Data Source
  KAKENHI-PROJECT-22591170
[Presentation] THE THERAPEUTIC VALUE OF ASPARAGINE SYNTHETASE DEFICIENCY IN LANGERHANS CELL HISTIOCYTOSIS2012
- Author(s)
  Kitoh T, Shimomura Y, Hori T, Terashima T, Yokoi T, Tsurusawa M
- Organizer
  the 28th Annual Meeting of the Histiocyte Society
- Place of Presentation
  London, UK
- Data Source
  KAKENHI-PROJECT-24590713
[Presentation] 思春期小児ALLの標準治療と最近の研究動向2011
- Author(s)
  鶴澤正仁
- Organizer
  第73回日本血液学会総会
- Place of Presentation
  名古屋国際会議場(名古屋)(教育講演)
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-22591170
[Presentation] CCLSGALL2004研究におけるIg/Tc遺伝子再構成のパターンとRPCR-MRDへの適応性2010
- Author(s)
  堀壽成、鶴澤正仁, 他
- Organizer
  第52回日本小児血液学会総会
- Place of Presentation
  国際会議場(大阪市)
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-22591170
[Presentation] 小児白血病の治療戦略と今後の展望
- Author(s)
  鶴澤正仁
- Organizer
  TOCHIGI 血液セミナー
- Place of Presentation
  宇都宮
- Invited
- Data Source
  KAKENHI-PROJECT-22591170
[Presentation] JPLSG成熟Ｂ細胞性リンパ腫研究（B-NHL０３）における有害事象解析
- Author(s)
  鶴澤正仁
- Organizer
  第５４回日本小児血液がん学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22591170
[Presentation] 小児白血病におけるＭＲＤ研究の進歩と今後の動向
- Author(s)
  鶴澤正仁
- Organizer
  第１０回小児白血病カンファレンス　in OKAYAMA
- Place of Presentation
  岡山
- Invited
- Data Source
  KAKENHI-PROJECT-22591170
[Presentation] 小児リンパ腫治療の進歩と今後の展望
- Author(s)
  鶴澤正仁
- Organizer
  第１８回愛媛小児血液・悪性腫瘍研究会
- Place of Presentation
  松山
- Invited
- Data Source
  KAKENHI-PROJECT-22591170
[Presentation] 造血器腫瘍における微少残存病変測定研究の進歩と今後の課題
- Author(s)
  鶴澤正仁
- Organizer
  ＡＬＬ学術講演会
- Place of Presentation
  博多
- Invited
- Data Source
  KAKENHI-PROJECT-22591170

1. FUJIMOTO Takeo (10037442)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. HORIBE Keizou (30209308)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. AGATA Hiroatsu (80288505)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HORI Toshinori (20308943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. Kitoh Toshiyuki (50243027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. YOKOI TOYOHARU (40200886)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. KATO HIDEFUMI (40298584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. HAMAKUBO TAKAO (90198797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. IMAIZUMI Masue (40191895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TSUCHIYA Shigeru (30124605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. IDE Hiroyuki (70022704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TSUKIMOTO Ichiro (70100964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YOKOYA Shohei (80231687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KAWAI Susumu (70116325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SAKI Kuniaki (40148325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TSURUSAWA Masahito 鶴澤 正仁

Research Projects

Research Products

Co-Researchers

Development of a predictive system of the sensitivity for L-asparaginase in tumor by monoclonal antibody

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

STUDY OF MINIMAL RESIDUAL DISEASE MEASUREMENTS AND CLINICAL APPLICATION IN PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on mechanism of ATRA-resistance and utility of MRD-monitoring in acute promyelocytic leukemia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A clinical study of MRD-based therapy for childhood ALL

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cytokines production in food-allergen reactive-lymphocytes in food hypersensitivity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Organ selectivity in food-allergen reactive-lymphocytes in food hypersensitivity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on Pathobiology and Heterogeneity of Childhood Hematologic Malignancies

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 小児造血器腫瘍の診断の手引き2012

Author(s)

Publisher

Data Source

[Book] 小児白血病リンパ腫の診療ガイドライン2011

Author(s)

Total Pages

Publisher

Data Source

[Book] 小児ALL治療でのMRD測定の役割は何か

Author(s)

Publisher

Data Source

[Journal Article] THE THERAPEUTIC VALUE OF ASPARAGINE SYNTHETASE DEFICIENCY IN LANGERHANS CELL HISTIOCYTOSIS.2013

Author(s)

Journal Title

Data Source

[Journal Article] 微小残存腫瘍量測定とその意義2012

Author(s)

Journal Title

Data Source

[Journal Article] 微小残存腫瘍量測定とその意義2012

Author(s)

Journal Title

Data Source

[Journal Article] Continuous and high-dose cytarabine combined chemotherapy in children with down syndrome and acute myeloid leukemia : Report from the Japanese children's cancer and leukemia study group (JCCLSG) AML 9805 down study2011

Author(s)

Journal Title

Data Source

[Journal Article] Assessment of late cardiotoxicity of pirarubicin (THP) in children with acute lymphoblastic leukemia2011

Author(s)

Journal Title

Data Source

[Journal Article] Flow cytometric analysis of de novo acute myeloid leukemia in childhood : report from the Japanese Pediatric Leukemia/Lymphoma Study Group2011

TSURUSAWA Masahito 鶴澤正仁