HASUO Hiroshi 蓮尾博

Researcher Number	90172882
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2008 – 2010: Kurume University, 医学部, 准教授 2005 – 2006: 久留米大学, 医学部, 助教授 2002 – 2003: 久留米大学, 医学部, 助教授 1995 – 1998: 久留米大学, 医学部, 助教授 1989 – 1991: 久留米大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Cerebral neurosurgery / Neurophysiology and muscle physiology / 神経・脳内生理学 Except Principal Investigator Neurophysiology and muscle physiology / General physiology / 神経・脳内生理学 / Neurophysiology and muscle physiology
Keywords	Principal Investigator 長期増強 / 修飾作用 / IPSP / 頭部外傷学 / 神経保護薬 / 脳・神経 / 薬理学 / 生理学 / 神経科学 / 頭部外傷モデル動物 … More Except Principal Investigator EPSP / 細胞内電極法 / Suprachiasmatic nucleus / ラット視交叉上核 / 自発性活動電位 / 内向き整流 / Hー電流 / カルシウム電流 / 興奮性シナプス後電位 / 抑制性シナプス後電位 / Rat / Central nervous system / Circadian rhythm / PIーturn over / Metabotropic receptors / 視交叉上核 / 静止・活動電位 / 細胞内微小電極法 / 脳スライス標本 / バゾプレッシン / ソマトスチタン / Electrophysiology / Intracellular recordings / Spontaneous activity / Inward rectification / Low-threshold Ca-current / IPSP / アデニレ-トサイクラ-ゼ / Cキナ-ゼ / カルモジュリン / リン酸化 / H電流 / M電流 / 自律神経節細胞 / 背外側中隔核細胞 / 背外側中隔核 / 脊椎動物 / パッチ・クランプ / アデニレ-ト・サイクラ-ゼ / フォ-スコリン / プロテインカイネ-ス / ハロセン / 遅延整流 / Adenylate cyclase / Cyclic AMP / Calmodulin / Phosporylation / Ionic currents / Primary afferent neurons / Sympathetic neurons / Dorsolateral septal nucleus / 交換神経節 / 副交換神経節 / IL-1β / サイトカイン / 過分極電位 / 中隔核 / グアニル酸シクラーゼ / シナプス前調節機構 / 自律神経節 / γ-アミノ酪酸 / パッチクランプ / G-蛋白 / GABA_B受容体 / インターロイキン-1β / 1L-1β活性フラグメント / 骨盤神経叢 / シナプス伝達 / 細胞内シグナル伝達機構 / 大脳中隔核 / 自律神経機能 / ストレス / インターロイキン / 骨盤内神経叢 / 交感神経節 / cytokine / interleukin-1beta / pelvic ganglia / sympathetic ganglia / depolarization / long-lasting hyperpolarization / GABA / presynaptic modulation / 外傷後てんかん / 実験的脳外傷モデルラット / 海馬スライス標本 / 光学的電位記録法 / 細胞外電極法 / パッチクランプ法 / post-traumatic epilepsy / experimental head injury model rat / hippocampal slice preparation / post-traumatic excitation / long-term potentiation (LTP) / whole-cell patch-clamp recordings / excitatory synaptic transmission / 脳外傷後遺症 / 歯状回及び海馬CA1領域 / ジアゼパム / グルタミン酸作動性神経 / NO除去効果 / 抑制性シナプス伝達 / てんかん / 記憶障害 / 頭部外傷モデル / 興奮性シナプス伝達 / グルタミン酸 / ガンマーアミノ酪酸 / brain injury / dentate gyrus / hippocampal CA1 / glutamate neurons / diazepam / NO scavengers / epilepsy / memory disturbance Less

Exploring a novel neuroprotectant for the treatment of acute traumatic brain injury using experimental model ratsPrincipal Investigator
- Principal Investigator
  
  HASUO Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kurume University
Contribution of neuronal regeneration in the hippocampus and dentate gyrus to the memory disturbance after traumatic brain injury
- Principal Investigator
  
  AKASU Takashi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Kurume University
Analysis of experimental brain injury on long-term potentiation of hippocampal neurons of the rat
- Principal Investigator
  
  AKASU Takashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  KURUME UNIVERSITY
Effects of interleukin-1beta on neurons in mammalian parasympathetic ganglia.
- Principal Investigator
  
  AKASU Takashi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Kurume University
Long-term potentiation of inhibitory postsynaptic potentials in rat lateral septal nucleus neuronsPrincipal Investigator
- Principal Investigator
  
  HASUO Hiroshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Kurume University
Modulation of synaptic transmission in rat septal nucleus neuronsPrincipal Investigator
- Principal Investigator
  
  TOKIMASA Takayuki, 蓮尾博
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Kurume University
Ionic currents of vertebrate nerve cells regulated by adenylate cyclase
- Principal Investigator
  
  TOKIMASA Takayuki
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Kurume University
Analysis of electrophysiological properties and transmissions in rat suprachiasmatic nucleus neurons
- Principal Investigator
  
  AKASU Takashi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Kurume University

All 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] Edaravone attenuates impairment of synaptic plasticity in granule cell layer of the dentate gyrus following traumatic brain injury.2011
- Author(s)
  Yamashita S, Hasuo H, Tokutomi T, Shigemori M, Akasu T
- Journal Title
  
  Kurume Med J 58(印刷中)
- NAID
  130002097076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591698
[Journal Article] Isolated guinea pig seminal vesicle contracts in response to mechanical stimuli without the activities of neurons and Kit-positive interstitial cells.2011
- Author(s)
  Takeya M,, Hayashi T, Ishimatsu M, Nakamura K, Hasuo H
- Journal Title
  
  J Physiol Sci 61
- Data Source
  KAKENHI-PROJECT-20591698
[Journal Article] Emodin, an active compound of Chinese medicine, attenuates the impairment of LTP after moderate traumatic brain injury (TBI) in rats.2010
- Author(s)
  蓮尾博, 武谷三恵
- Journal Title
  
  Neurosci Res 68
- Data Source
  KAKENHI-PROJECT-20591698
[Journal Article] Emodin attenuates the impairment of LTP after traumatic brain injury in rat hippocampus.2009
- Author(s)
  Takeya M, Hasuo H, Akasu T
- Journal Title
  
  Neurosci Res 65
- Data Source
  KAKENHI-PROJECT-20591698
[Journal Article] Impairment of LTP in hippocampal neurons of the traumatic brain injury model rats and its attenuation by neuroprotective drugs.2009
- Author(s)
  Hasuo H, Takeya M, Ooba S, Yamashita S, Akasu T
- Journal Title
  
  J Physiol Sci 59
  
  Pages: 366-366
- Data Source
  KAKENHI-PROJECT-20591698
[Journal Article] ラット海馬CA1ニューロンにおける脳外傷後過興奮とジアゼパムの効果.2009
- Author(s)
  大場さとみ,山下伸,蓮尾博,徳富孝志,赤須崇,重森稔
- Journal Title
  
  神経外傷 32
  
  Pages: 61-67
- NAID
  10027501396
- Data Source
  KAKENHI-PROJECT-20591698
[Journal Article] 中隔核における5-HT_<1B>受容体の役割2009
- Author(s)
  蓮尾博
- Journal Title
  
  生体の科学 60
  
  Pages: 430-431
- Data Source
  KAKENHI-PROJECT-20591698
[Journal Article] 医学生が階層的に活用できる腸管運動の動画教材の作成.2009
- Author(s)
  武谷三恵,林篤正,石松秀,蓮尾博,赤須崇
- Journal Title
  
  医教育 40
  
  Pages: 89-89
- Data Source
  KAKENHI-PROJECT-20591698
[Journal Article] 中隔核における5-HT1B受容体の役割.2009
- Author(s)
  蓮尾博,赤須崇
- Journal Title
  
  生体の科学 60
  
  Pages: 430-431
- Data Source
  KAKENHI-PROJECT-20591698
[Journal Article] Mild hypothermia prevents post-traumatic hyperactivity of excitatory synapses in rat hippocampal CA1 pyramidal neurons.2009
- Author(s)
  Ooba S, Hasuo H, Shigemori M, Yamashita S, Akasu T
- Journal Title
  
  Kurume Med J 56
  
  Pages: 49-59
- NAID
  130000259041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591698
[Journal Article] The radical scavenger edaravone suppresses the exogenous nitric oxide [NO]-induced potentiation of perforant path synapse of the dentate gyrus in vitro.2008
- Author(s)
  Hasuo H, Yamashita S, Shigemori M, Akasu T
- Journal Title
  
  Neurosci Res 61
- Data Source
  KAKENHI-PROJECT-20591698
[Journal Article] Diazepam attenuates the post-traumatic hyperactivity of excitatory synapses in rat hippocampal CA1 neurons.2008
- Author(s)
  Ooba S, Hasuo H, Shigemori M, Akasu T
- Journal Title
  
  Neurosci Res 62
  
  Pages: 195-205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591698
[Journal Article] Dopamine induced long-lasting enhancement of the EPSP in rat dorsolateral septal nucleus neurons2007
- Author(s)
  Hasuo H
- Journal Title
  
  J Physiol Sci 57(Suppl)
- NAID
  130007038587
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500279
[Journal Article] Dopamine induced long-lasting enhancement of the EPSP in rat dorsolateral septal nucleus neurons2007
- Author(s)
  Hasuo H
- Journal Title
  
  J Physiol Sci 57-Suppl
- NAID
  130007038587
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500279
[Journal Article] Facilitation of glutamatergic excitatory synaptic transmission in hippocampal CA1 regions of traumatic brain injury model rats2006
- Author(s)
  Hasuo H
- Journal Title
  
  J Physiol Sci 56-Suppl
- NAID
  130005448421
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500279
[Journal Article] Facilitation of glutamatergic excitatory synaptic transmission in hippocampal CA1 regions of traumatic brain injury model rats2006
- Author(s)
  Hasuo H
- Journal Title
  
  J Physiol Sci 56(Suppl)
- NAID
  130005448421
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500279
[Journal Article] Activation of adenosine Ai receptors contributes to the depression of EPSPs induced by emodin in rat hippocampal CA1 pyramidal neurons in vitro2005
- Author(s)
  Hasuo H
- Journal Title
  
  Neurosci Res 52-Suppl
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500279
[Journal Article] Contribution of endogenous adenosine to the effect of emodin on the excitatory synaptic transmission in rat hippocampal CA1 pyramidal neurons in vitro2005
- Author(s)
  Hasuo H
- Journal Title
  
  The Fifth Japan-Korea Joint Symposium of Brain Sciences, and Cardiac and Smooth Muscles Program & Abstracts
  
  Pages: 37-37
- Data Source
  KAKENHI-PROJECT-17500279
[Journal Article] Contribution of endogenous adenosine to the effect of emodin on the excitatory synaptic transmission in rat hippocampal CA1 pyramidal neurons in vitro2005
- Author(s)
  Hasuo H
- Journal Title
  
  The Fifth Japan-Korea Joint Symposium of Brain Sciences, and Cardiac and Smooth Muscles Program ＆ Abstracts
  
  Pages: 37-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500279
[Journal Article] Activation of adenosine A_1 receptors contributes to the depression of EPSPs induced by emodin in rat hippocampal CA1 pyramidal neurons in vitro2005
- Author(s)
  Hasuo H
- Journal Title
  
  Neurosci Res 52(Suppl)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500279
[Presentation] Emodin, an active compound of Chinese medicine, attenuates the impairment of LTP after moderate traumatic brain injury (TBI) in rats.2010
- Author(s)
  蓮尾博
- Organizer
  The 33rd Annual Meeting of the Japan Neuroscience Society (Neuro 2010)
- Place of Presentation
  神戸
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20591698
[Presentation] Impairment of LTP in hippocampal neurons of the traumatic brain injury model rats and its attenuation by neuroprotective drugs2009
- Author(s)
  Hasuo H
- Organizer
  The XXXVI IUPS2009・The 86th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  京都
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-20591698
[Presentation] Impairment of LTP in hippocampal neurons of the traumatic brain injury model rats and its attenuation by neuroprotective drugs. The XXXVI International Congress of Physiological Sciences (IUPS2009)2009
- Author(s)
  蓮尾博
- Organizer
  The 86th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  京都
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-20591698
[Presentation] 頭部外傷後のシナプス可塑性障害に対するエダラボンの効果.2008
- Author(s)
  蓮尾博
- Organizer
  生理学研究所研究会「新たなコンセプトでシナプス伝達機構を考える」
- Place of Presentation
  岡崎
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-20591698
[Presentation] The radical scavenger edaravone suppresses the exogenous nitric oxide [NO]-induced potentiation of perforant path synapse of the dentate gyrus in vitro.2008
- Author(s)
  蓮尾博
- Organizer
  The 31st Annual Meeting of the Japan Neuroscience Society (Neuro2008)
- Place of Presentation
  東京
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-20591698
[Presentation] The radical scavenger edaravone suppresses the exogenous nitric oxide[NO]-induced potentiation of perforant path synapse of the dentate gyrus in vitro.2008
- Author(s)
  Hasuo H
- Organizer
  The 31st Annual Meeting of the Japan Neuroscience Society
- Place of Presentation
  東京
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-20591698
[Presentation] 頭部外傷後のシナプス可塑性障害に対するエダラボンの効果2008
- Author(s)
  蓮尾博
- Organizer
  平成20年度生理学研究所研究会『新たなコンセプトでシナプス伝達機構を考える』
- Place of Presentation
  岡崎
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-20591698

1. AKASU Takashi (60113213)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. TOKIMASA Takayuki (50155511)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. TAKEYA Mitsue (30289433)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. TSURUSAKI Masashi (60207454)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results

HASUO Hiroshi 蓮尾 博

Research Projects

Research Products

Co-Researchers

Exploring a novel neuroprotectant for the treatment of acute traumatic brain injury using experimental model ratsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Contribution of neuronal regeneration in the hippocampus and dentate gyrus to the memory disturbance after traumatic brain injury

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of experimental brain injury on long-term potentiation of hippocampal neurons of the rat

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of interleukin-1beta on neurons in mammalian parasympathetic ganglia.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Long-term potentiation of inhibitory postsynaptic potentials in rat lateral septal nucleus neuronsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Modulation of synaptic transmission in rat septal nucleus neuronsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ionic currents of vertebrate nerve cells regulated by adenylate cyclase

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of electrophysiological properties and transmissions in rat suprachiasmatic nucleus neurons

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Edaravone attenuates impairment of synaptic plasticity in granule cell layer of the dentate gyrus following traumatic brain injury.2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Isolated guinea pig seminal vesicle contracts in response to mechanical stimuli without the activities of neurons and Kit-positive interstitial cells.2011

Author(s)

Journal Title

Data Source

[Journal Article] Emodin, an active compound of Chinese medicine, attenuates the impairment of LTP after moderate traumatic brain injury (TBI) in rats.2010

Author(s)

Journal Title

Data Source

[Journal Article] Emodin attenuates the impairment of LTP after traumatic brain injury in rat hippocampus.2009

Author(s)

Journal Title

Data Source

[Journal Article] Impairment of LTP in hippocampal neurons of the traumatic brain injury model rats and its attenuation by neuroprotective drugs.2009

Author(s)

Journal Title

Data Source

[Journal Article] ラット海馬CA1ニューロンにおける脳外傷後過興奮とジアゼパムの効果.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 中隔核における5-HT_<1B>受容体の役割2009

Author(s)

HASUO Hiroshi 蓮尾博