Hirano Toshihiko 平野俊彦

… Alternative Names

HIRANO Toshihiko 平野俊彦

HIRANO TOSHIHIKO 平野俊彦

Less

Researcher Number	90173252
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2015 – 2017: 東京薬科大学, 薬学部, 教授 2008 – 2013: 東京薬科大学, 薬学部, 教授 2007 – 2008: Tokyo University of Pharmacy and Life Science, 薬学部, 准教授 1994 – 2006: 東京薬科大学, 薬学部, 助教授 1994 – 1995: 東京薬科大学, 臨床薬理学, 助教授 1993: 東京薬科大学, 薬学部, 講師 1986 – 1987: 東京薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Medical pharmacy / 応用薬理学・医療系薬学 Except Principal Investigator 応用薬理学・医療系薬学 / Medical pharmacy / Fluid engineering / General surgery
Keywords	Principal Investigator 免疫抑制薬 / 末梢血リンパ球 / サイトカイン / グルココルチコイド / 末梢血単核細胞 / 腎移植 / シクロスポリン / nephrotic syndrome / drug sensitivity / peripheral lymphocytes … More / 自己免疫疾患 / 臓器移植 / ネフローゼ症候群 / 薬物感受性 / ヒト末梢血リンパ球 / ヒト末梢血単核細胞 / 抗菌薬 / スーパー抗原 / ミコフェノール酸 / タクロリムス / T細胞増殖 / 慢性腎不全 / インスリン受容体 / 単球 / 副腎皮質ステロイド薬 / 個別医療 / 薬物耐性 / 慢性腎不全患者 / 末梢血単核細胞（PBMC） / インスリン / organ transplantation / autoimmune diseases / interleukin 2 / glucocorticoid / superantigen / Staphylococcus aureus / sensitivities to immunosuppressive drugs / peripheral blood lymphocytes drugs / アトピー性皮膚炎 / インターロイキン2mRNA / インターロイキン2 / 副腎皮質ステロイド / 黄色ブドウ球菌 / 免疫抑制薬感受性 / LDL-receptor / cyclosporine / LDL-cholesterol / serum total cholesterol / immunosuppressive drugs / トリグリセリド / 血清脂質濃度 / T細胞 / CD3陽性細胞 / LDL受容体 / LDLコレステロール / 血清総コレステロール / resistant mechanisms / individualized drug therapy / renal transplantation / antoimmune disorders / immunosuppressants / マイトゲン試験法 / 免疫抑制剤 / 薬剤感受性 / アポトーシス / 薬剤耐性 / 血清コレステロール / グルココルチコイド受容体 / 潰瘍性大腸炎 / 気管支喘息 / 免疫抑制療法の適正化 / 薬剤耐性機構 / cytotoxicity / mitogen-responding growth / human peripheral-blood lymphocytes / apoptosis-inducing activity / naturally occurring organic compounds / human leukemia cell line / ユリ科由来ステロイド / 細胞毒性 / マイトゲン応答性増殖 / アポトーシス誘導作用 / 天然有機化合物 / ヒト白血病細胞株 / 亜ヒ酸(As203) / 抗微生物薬 / ビタミンK / 亜ヒ酸 / マクロライド系抗生物質 / MAPK / 制御性T細胞(T reg) / 末梢血単核細胞(PBMC) / CD25陽性細胞 / CD4陽性細胞 / 抗癌薬 / ビタミンK誘導体 / 制御性T細胞 / T細胞マイトゲン / 免疫抑制薬耐性 / ヒ素化合物 / 脂溶性ビタミン / 制御性 T 細胞 / ヒト末梢リンパ球 / 細菌由来スーパー抗原 / JNK / MAPキナーゼ / ビタミンD3誘導体 / インターロイキン-2 / 免疫抑制薬耐性の分子機序 / ロキシスロマイシン / ペプスタチン / カテプシン / 溶血性連鎖球菌 / インターロイキンー2 / 薬物耐性機序 … More Except Principal Investigator シクロスポリン / 腎移植 / プレドニゾロン / methylprednisolone / glucocorticoid / allograft / survival rate / prednisolone / drug selection / kidney transplantation / Immunosuppression / Renal Transplantation / 急性拒絶反応 / 免疫抑制剤 / ステロイド / タクロリムス / メチルプレドニゾロン / リンパ球感受性 / 再生医療 / 医療機器 / 移植医療 / 臓器再生 / 流体工学 / 医用工学 / 灌流保存 / 機能評価 / 機械灌流 / 臓器工学 / 臓器移植 / Predictive Deagnosis of Acute Allograft Rejection / Prednisolone Sensitivity of Lymphocyte / Prednisolone / Serum Cortisol / HPLC / 薬物投与計画 / 副腎皮質機能 / 血中濃度 / 内因性コルチゾール / デキサメサゾン抑制試験 / 急性拒絶反応予測診断 / リンパ球プレドニゾロン感受性 / 免疫抑制 / コルチゾール血中濃度 / 腎臓移植 / 高性能液体クロマトグラフィー / peripheral blood lymphocyte / 死体腎移植 / 生体腎移植 / 生着率 / 慢性腎不全 / グルココルチコイド耐性 / peripheal blcal lymphoeytes / pecipheral blccd lymplcayte / methyl prednisolone / gluco corticoid / Acute rejection / Cicrosporin / Glucocorticoid / Lymphocyte sensitivity / グルココルチコイド / 腎移植患者 / 免疫抑制剤投与法 / 薬剤選択 / FK506 / 薬剤感受性 / シクロフィリン40 / FKBP52 / FKBP51 / 薬力学的相互作用 / カルシニュリン阻害薬 / ステロイド感受性 / フォーマコダイナミクス / FKBP / 相互作用 / ファーマコダイナミクス / カルシニューリン阻害薬 / 感受性 / バイオマーカー / ステロイド離脱 / コルチゾール Less

Effects of insulin on pharmacodynamics of immunosuppressive drugs in human peripheral T lymphocytesPrincipal Investigator
- Principal Investigator
  
  Hirano Toshihiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Evaluation of Liver flow dynamics for organ preservation, recovery and assessment to develop future medical devices
- Principal Investigator
  
  obara Hiromichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fluid engineering
- Research Institution
  Tokyo Metropolitan University
Synergistic Effects of Calcineurin Inhibitors and Steroids on Steroid Sensitivity of Peripheral Blood Mononuclear Cells
- Principal Investigator
  
  TAKEUCHI Hironori
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Effects of several antibiotics on proliferation and regulatory T cell frequency in human lymphocytes stimulated with superantigenPrincipal Investigator
- Principal Investigator
  
  HIRANO Toshihiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Steroid Withdrawal Based on Lymphocyte Sensitivity to Endogenous Steroid in Renal Transplant Recipients
- Principal Investigator
  
  TAKEUCHI Hironori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Molecular mechanisms for resistance to immunosuppressive drugs in human lymphocytes stimulated with bacterial superantigen and the effects of antibiotics.Principal Investigator
- Principal Investigator
  
  HIRANO Toshihiko
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Relationship between sensitivities of peripheral blood-mononuclear cells to immunosuppressive drugs and Staphylococcus aureus infectionPrincipal Investigator
- Principal Investigator
  
  HIRANO Toshihiko
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Sciences
Influence of serum lipids on lymphocyte sensitivity to immunosuppressive drugs and its clinical implication in patients with nephrosis.Principal Investigator
- Principal Investigator
  
  HIRANO Toshihiko
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tokyo University of Pharmacy and Life Science
Study on individual immunosuppressive therapy based on peripheral-blood lymphocyte-sensitivity to immunosuppressive drugs and the mechanisms on drug resistancePrincipal Investigator
- Principal Investigator
  
  HIRANO Toshihiko
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tokyo University of Pharmacy and Life Science
Selection of steroids in accordance with lymphocyte abilities and improvement of clinical outcomes of kidney transplantation.
- Principal Investigator
  
  OKA Kitaro
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  The Tokyo University of Pharmacy and Life Sciences
Research for natural compounds inducing apoptosis in leukemia cells without foxicity on normal immune cells.Principal Investigator
- Principal Investigator
  
  HIRANO Toshihiko
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tokyo University of Pharmacy and Life Science
Immunosuppressive therapy based on lymphocyte sensitivity in renal transplant patients
- Principal Investigator
  
  KOZAKI Masami
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Tokyo Medical College
Improvement of assay method of glucocorticoids and its application to the immunosuppressive drug therapy of renal transplantation.
- Principal Investigator
  
  OKA KITARO
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Tokyo College of Pharmacy

All 2018 2017 2016 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Patent

[Journal Article] 心停止ドナーからのブタ腎保存における酸素化復温灌流保存方法の有用性の研究2018
- Author(s)
  森井湧太、松野直徒、森戸規之、絵野沢伸、平野俊彦,古川博之、小原弘道
- Journal Title
  
  移植
  
  Volume: 印刷中
- NAID
  130006743885
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H03922
[Journal Article] Optimum perfusate volume of purified subnormothermic machine perfusion for porcine liver donated after cardiac deat2018
- Author(s)
  Hiromichi Obara, Noriyuki Morito, Naoto Matsuno, Ryo Yoshikawa, Mikako Gouchi, Masahide Otani, Tatsuya Shonak, Hiroyuki Takahashi, Shin Enosawa, Toshihiko Hirano, Hiroyuk iFurukawa
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 印刷中 Issue: 9 Pages: 2830-2833
- DOI
  10.1016/j.transproceed.2018.03.055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H03922
[Journal Article] Ex vivo reperfusion model to evaluate the utility of machine preservation for porcine liver donated after cardiac death2017
- Author(s)
  Ryo Yoshikawa; Hiromichi Obara; Naoto Matsuno; Noriyuki Morito; Mikako Gouchi; Masahide Otani; Tatsuya Shonaka; Hiroyuki Takahashi; Shin Enosawa; Toshihiko Hirano; Hiroyuki Furukawa
- Journal Title
  
  Transpl Proc
  
  Volume: Transpl Proc Issue: 9 Pages: 2826-2829
- DOI
  10.1016/j.transproceed.2018.04.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10503, KAKENHI-PROJECT-15H03922
[Journal Article] Effects of insulin on pharmacodynamics of immunosuppressive drugs against mitogen-activated human peripheral-blood mononuclear cells.2016
- Author(s)
  Chen S, Sugiyama K, Inamura M, Tanaka S, Onda K, Huijun Y, Hirano T.
- Journal Title
  
  Immunopharmacology and Immunotoxicology
  
  Volume: 38 Issue: 5 Pages: 372-378
- DOI
  10.1080/08923973.2016.1214143
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08081
[Journal Article] Synergistic Effects of Calcineuri n Inhibitors and Steroids on Steroid Se nsitivity of Peripheral Blood Mononuclea r Cells2014
- Author(s)
  Hironori Takeuchi, Hitoshi Iwamoto, Yuki Nakamura, Toshihiko Hirano, Osamu Kon no, Yu Kihara, Naokazu Chiba, Takayoshi Yokoyama, Kiminori Takano, Tatsunori Toraishi, Kiyoshi Okuyama, Chie Ikeda, S achiko Tanaka, Kenji Onda, Akiko Soga, Yukiko Kikuchi, Takashi Kawaguchi, Shig eyuki Kawachi, Sakae Unezaki, Motohide Shimazu
- Journal Title
  
  Cell Medicine
  
  Volume: (accepted)
- Data Source
  KAKENHI-PROJECT-23590201
[Journal Article] Higher sensitivity of peripheral blood lymphocytes to endogenous glucocorticoid in renal transplant recipients treated with tacrolimus, as compared to those treated with cyclosporine2012
- Author(s)
  Gulimire Muhetaer, Hironori Takeuchi, Sogo Akizuki, Hitoshi Iwamoto, Motohide Shimazu, Sakae Unezaki, Toshihiko Hirano
- Journal Title
  
  Cell Medicine
  
  Volume: 3 Issue: 1-3 Pages: 75-80
- DOI
  10.3727/215517912x639423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590201
[Journal Article] Higher sensitivity of peripheral blood ly mphocytes to endogenous glucocorticoid in renal transplant recipients treated w ith tacrolimus, as compared to those tr eated with cyclosporine2012
- Author(s)
  Gulimire Muhetaer, Hironori Takeuchi, So go Akizuki, Hitoshi Iwamoto, Motohide S himazu, Sakae Unezaki, Toshihiko Hirano
- Journal Title
  
  Cell Medicine
  
  Volume: 3 Pages: 75-80
- Data Source
  KAKENHI-PROJECT-23590201
[Journal Article] Suppressive effects of peptide antibiotics against proliferation and cytokine production in mitogen-activated human peripheral-blood mononuclear cells2011
- Author(s)
  Masaki Maeda, Sachiko Tanaka, Hitomi Ishizawa, Yurie Nakamura, Kenji Onda, Toshihiko Hirano
- Journal Title
  
  Arzneimittelforschung
  
  Volume: 61 Issue: 12 Pages: 1-15
- DOI
  10.1055/s-0031-1300595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590145
[Journal Article] Effects of Inorganic and Organic Arsenic Compounds on Growth and Apoptosis of Human T-Lymphoblastoid Leukemia Cells2011
- Author(s)
  Eri Hikita, Mariko Arai, Sachiko Tanaka, Kenji Onda, Hiroya Utsumi, Bo Yuan, Hiroo Toyoda, Toshihiko Hirano
- Journal Title
  
  Anticancer Res
  
  Volume: 30 Pages: 4169-4178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590145
[Journal Article] Antiproliferative and anti-invasive effects of inorganic and organic arsenic compounds on human and murine melanoma cells in vitro2011
- Author(s)
  Yoko Hiwatashi, Hiroko Tadokoro, Kayo Henmi, Mariko Arai, Toshikazu Kaise, Sachiko Tanaka, Toshihiko Hirano
- Journal Title
  
  J Pharm Pharmacol
  
  Volume: 63 Issue: 9 Pages: 1202-1210
- DOI
  10.1111/j.2042-7158.2011.01330.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590145
[Journal Article] Steroid Withdrawal Based on Lymphocyte Sensitivity to Endogenous Cortisol in Renal Transplant Recipients2011
- Author(s)
  H Takeuchi, N Matsuno, T Hirano, M Gulimire, K Hama, Y Nakamura,H Iwamoto,T Kawaguchi, K Okuyama, S Unezaki, Nagao T
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 34（10） Pages: 1578-1583
- Data Source
  KAKENHI-PROJECT-23590201
[Journal Article] Suppressive efficacies of antimicrobial agents against human peripheral-blood mononuclear cells stimulated with T cell mitogen and bacterial supeientigen2010
- Author(s)
  Maeda M, Ishii H, Tanaka S, Onda K, Hirano T
- Journal Title
  
  Arzneim Forsch/Drug Res
  
  Volume: 60 Pages: 760-768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590145
[Journal Article] Clinical implicatio of the type 1/type 2 balance of helper T cells and P-glycoprotein function in peripheral T lymphocytes of myasthenia gravis patients.2010
- Author(s)
  Masuda H, Tanaka S, Iwase Y, Hirano T, Utsumi H
- Journal Title
  
  Eur J Pharmacol 627(1-3)
  
  Pages: 325-331
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] Clinical significance of cellular pharmacodynamics of tacrolimus in living-donor liver transplantation.2009
- Author(s)
  Mijiti A, Matsuno N, Takeuchi H, Unezaki S, Nagao T, Hirano T
- Journal Title
  
  Cell Transplantation 18
  
  Pages: 637-664
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] Suppressive efficacies of roxlthromycin against human peripheral-blood mononuclear cells stimulated with hemolytic streptococci superantigen2009
- Author(s)
  Kamogawa S, Kagami K, Maeda M, Arai K, Okubo Y, Tsuboi R, Hirano H
- Journal Title
  
  European Journal of Pharmacology 602
  
  Pages: 439-447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] Suppressive efficacies of roxithromycin against human peripheral-blood mononuclear cells stimulated with hemolytic streptococci superantigen2009
- Author(s)
  Kamogawa S, Kagami K, Maeda M, Arai K, Okubo Y, Tsuboi R, Hirano T
- Journal Title
  
  Eur J Pharmacol 602
  
  Pages: 439-447
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] Comparative study of the cellular pharmacodynamics of calcineurin inhibitors between patients with chronic renal failure awaiting renal transplantation and cirrhosis patients awaiting liver transplantation.2009
- Author(s)
  Kihara Y, Matsuno N, Mijiti A, Nagao T, Takeuchi H, Unezaki S, Hirano T
- Journal Title
  
  Cell Transplantation 18
  
  Pages: 639-646
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] Cyclosporine pharmacological efficacy estimated by lymphocyte immunosuppressant sensitivity test (LIST) before and after renal transplantation.2009
- Author(s)
  Sugiyama K, Isogai K, Toyama A, Satoh H, Saito K, Nakagawa Y, Tasaki M, Takahashi k, Saito N, Hirano T
- Journal Title
  
  J Clin Pharm Ther 34
  
  Pages: 539-545
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] 腎移植患者における内因性コルチゾールのリンパ球感受性に基づくステロイド減量・離脱の可能性2009
- Author(s)
  竹内裕紀、松野直徒、平野俊彦、畝崎榮、長尾桓
- Journal Title
  
  臨床薬理の進歩 30
  
  Pages: 128-136
- Data Source
  KAKENHI-PROJECT-20590159
[Journal Article] Suppressive efficacies of roxithromycin against human peripheral-blood mononuclear cells stimulated with hemolytic streptococci superantigen2009
- Author(s)
  Kamogawa S, Kagami K, Maeda M, Arai K., Okubo Y, Tsuboi R., Hirano T
- Journal Title
  
  Eur J Pharmacol 602
  
  Pages: 439-447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] 薬剤師による処方支援・28PKおよびPDに基づく腎移植免疫抑制療法の処方支援2008
- Author(s)
  竹内裕紀、平野俊彦、畝崎榮
- Journal Title
  
  医薬ジャーナル 44(5)
  
  Pages: 1349-1355
- NAID
  40016057653
- Data Source
  KAKENHI-PROJECT-20590159
[Journal Article] Suppressive potencies of calcineurin inhibitors against the mitogen-induced blastogenesis of peripheral-blood mononuclear cells of myasthenia gravis patients.2008
- Author(s)
  Tanaka S, Nakajima, K, Hirano T, Oka K, Saito T
- Journal Title
  
  J Pharm Pharmacol 60
  
  Pages: 1341-1346
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] Influence of bacterial superantigen TSST-1 against the anti-proliferative efficacy of immunosuppressive drugs and interleukin 2 production in peripheral blood mononuclear cells of hemodialysis patients and healthy subjects.2008
- Author(s)
  Taira S, Katsuyama K, Konno O, Ashizawa T, Matsuno N, Nagao T, Hirano T
- Journal Title
  
  Immunopharmacol Immunotoxicol 30
  
  Pages: 1-14
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] Pharmacodynamic parameters of immunosuppressive drugs are not correlated with age, duration of dialysis, percentage of lymphocytes or lymphocyte stimulation index in renal transplant recipients.2008
- Author(s)
  Sugiyama K, Isogai K, Toyama A, Satoh H, Saito K, Nakagawa Y, Tasaki M, Takahashi K, Saito N, Hirano T
- Journal Title
  
  Biol Pharm Bull 31(11)
  
  Pages: 2146-2149
- NAID
  110006968103
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] 長尾桓敗血症患者末梢血単核細胞のマイトゲン応答性およびグルココルチコイド感受性2008
- Author(s)
  平野俊彦、松野直徒、池田寿昭、竹内裕紀、畝崎榮、虎石竜典、奥山清、明石貴雄、阿不都許庫尓米吉提、木原優、今野理、城島嘉麿、赤司勲、平良眞一郎、浜耕一郎、中村有紀、岩本整、葦澤龍人
- Journal Title
  
  Organ Biology 15
  
  Pages: 49-55
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] P-glycoprotein function in peripheral blood mononuclear cells of myasthenia gravis patients treated with tacrolimus.2007
- Author(s)
  Tanaka S, Hirano T, Saitoh T, Wakata N, Oka K
- Journal Title
  
  Biol Pharm Bull 30
  
  Pages: 291-296
- NAID
  110006162846
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] Cellular pharmacodynamics of immunosuppressive drugs for individualized medicine (review).2007
- Author(s)
  Toshihiko Hirano.
- Journal Title
  
  Int Immunopharmacol 7
  
  Pages: 3-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590125
[Journal Article] Bacterial superantigen TSST-1 attenuates suppressive efficacy of glucocorticoids and calcineurin inhibitors against blastogenesis of peripheral blood mononuclear cells from patients with chronic renal failure on hemodialysis treatment.2007
- Author(s)
  Konno O, Hirano T, Katsuyama K et al.
- Journal Title
  
  Transplant Immunol 17
  
  Pages: 187-192
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590125
[Journal Article] アトピー性皮膚炎患者における末梢血単核細胞の免疫抑制薬感受性と黄色ブドウ球菌由来スーパー抗原抗体価との関連2007
- Author(s)
  福島悠代、平野俊彦、住田治子、小宅慎一、坪井良治、岡希太郎
- Journal Title
  
  臨床薬理 38
  
  Pages: 103-107
- NAID
  130004541187
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] Comparative study of the effects of betamethasone butyrate propionate, vitamin D_3 derivatives, and cyclosporine on human lymphocyte-proliferation stimulated with a hemolytic streptococci derived superantigen.2007
- Author(s)
  Arai K, Uchiyama T, Okubo Y, Tsuboi R, Oka K, Hirano T.
- Journal Title
  
  Eur J Pharmacol 571
  
  Pages: 222-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] Cellular pharmacodynamics of immunosuppressive drugs for individualized medicine (review).2007
- Author(s)
  Hirano T
- Journal Title
  
  Int Immunopharmacol 7
  
  Pages: 3-22
- Data Source
  KAKENHI-PROJECT-16590125
[Journal Article] Staphylococcus aureus superantigens decreases FKBP51mRNA expression and cell response to suppressive efficacy of glucocorticoid in human peripheral blood mononuclear: Possible implication of MAPK pathways.2007
- Author(s)
  Fukushima H, Hirano T, Oka K
- Journal Title
  
  Eur J Pharmacol 570(1-3)
  
  Pages: 222-228
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] Cellular pharmacodynamics of immunosuppressive drugs for individualized medicine (review).2007
- Author(s)
  Hirano T
- Journal Title
  
  Int Immunopharmacol 7・1
  
  Pages: 3-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590125
[Journal Article] Staphylococcus aureus superantigens decreases FKBP51mRNA expression and cell response to suppressive efficacy of glucocorticoid in human peripheral blood mononuclear cells: Possible implication of MAPK pathways.2007
- Author(s)
  Fukushima H, Hirano T, Oka K.
- Journal Title
  
  Eur J Pharmacol 570
  
  Pages: 222-228
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] Comparative study of the effects of betamethasone butyrate propionate, vitamin D3 derivatives, and cyclosporine on human lymphocyte-proliferation stimulated with a hemolytic streptococci derived superantigen.2007
- Author(s)
  Arai K, Uchiyama T, Okubo Y, Tsuboi R, Oka K, Hirano T
- Journal Title
  
  Eur J Pharmacol 571(2-3)
  
  Pages: 222-230
- Data Source
  KAKENHI-PROJECT-19590162
[Journal Article] 免疫抑制薬におけるpharmacodynamics2006
- Author(s)
  平野俊彦
- Journal Title
  
  移植 41・3
  
  Pages: 101-108
- NAID
  10029277484
- Data Source
  KAKENHI-PROJECT-16590125
[Journal Article] Bacterial Superantigen TSST-1 attenuates suppressive efficacy of glucocorticoids and calcineurin inhibitors against blastogenesis of peripheral blood mononuclear cells from patients with antineutrophil cytoplasmic antibody-associated vasculitis and nephrosis.2006
- Author(s)
  Hirano T, Fukushima H, Sasaki Y, Yoshikawa N, Yoshida M, Oka K
- Journal Title
  
  Int Immunopharamacol 6
  
  Pages: 924-934
- Data Source
  KAKENHI-PROJECT-16590125
[Journal Article] リンパ球感受性に基づく免疫抑制薬のテーラーメード医療2006
- Author(s)
  平野俊彦
- Journal Title
  
  今日の移植 19・6
  
  Pages: 671-678
- Data Source
  KAKENHI-PROJECT-16590125
[Journal Article] The role of immune response to Staphylococcus aureus superantigens and disease severity to the sensitivity to tacrolimus in atopic dermatitis.2006
- Author(s)
  Fukushima H, Hirano T, Shibayama N, Miwa K, Ito T, Saito M, Sumida H, Oyake S, Tsuboi R, Oka K
- Journal Title
  
  Int Arch Allergy Immunol 141
  
  Pages: 281-289
- Data Source
  KAKENHI-PROJECT-16590125
[Journal Article] 免疫抑制薬のpharmacokineticsとpharmacodynamics2006
- Author(s)
  平野俊彦
- Journal Title
  
  今日の移植 19・2
  
  Pages: 123-132
- Data Source
  KAKENHI-PROJECT-16590125
[Journal Article] Higher sensitivity of peripheral blood lymphocytes to endogenous glucocorticoid in renal transplant recipients treated with tacrolimus, as compared to those treated with cyclosporine
- Author(s)
  Gulimire Muhetaer, Hironori Takeuchi, Sogo Akizuki, Sakae Unezaki, Hitoshi Iwamoto, Motohide Shimazu, Toshihiko Hirano
- Journal Title
  
  Cell Medicine
  
  Volume: (accepted)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590159
[Patent] 特許権2005
- Inventor(s)
  柴山尚子, 三和敬史, 福島悠代, 平野俊彦
- Industrial Property Rights Holder
  東レ株式会社, 東京薬科大学
- Industrial Property Number
  2005-091052
- Filing Date
  2005-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590125
[Presentation] Optimization of Purified Subnormothermic Machine Perfusion for Porcine Liver Donated after Cardiac Death2018
- Author(s)
  Hiromichi Obara, Noriyuki Morito, Naoto Matsuno, Ryo Yoshikawa, Toshihiko Hirano, Shin Enosawa, Hiroyuki Furukawa
- Organizer
  15th Congress of the Asian Society of Transplantation（CAST2017）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03922
[Presentation] ,マージナルドナーの移植適用拡大に向けた酸素化復温灌流法の体外血液再灌流モデルによる検討2018
- Author(s)
  森井湧太，小原弘道，松野直徒，絵野沢伸，吉野聡，中田智裕，中条哲也，平野俊彦，古川博之
- Organizer
  ,臨床腎移植学会
- Data Source
  KAKENHI-PROJECT-15H03922
[Presentation] 分割肝移植への機械灌流法適用の検討2017
- Author(s)
  吉川遼，小原弘道，松野直徒,，森戸規之，吉野聡，中田智裕，中條哲也，絵野沢伸，平野俊彦，古川博之
- Organizer
  臓器保存生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-15H03922
[Presentation] 腎機能回復のための酸素化復温機械灌流の体外血液再灌流モデルを用いた評価2017
- Author(s)
  森井勇太，小原弘道，松野直徒,，絵野沢伸，吉野聡，中田智裕，中條哲也，平野俊彦，古川博之
- Organizer
  臓器保存生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-15H03922
[Presentation] The examination of perfusate with artificial oxgen carrier under subnormothermic machine perfusion for DCD liver grafts in pigs2017
- Author(s)
  Shonaka Tatsuya,Naoto Matsuno, Noriyuki Morito, Ryo Yoshikawa, Hiromichi Obara, Shin Enosawa, Toshihiko Hirano, Hiroyuki Furukawa
- Organizer
  15th Congress of the Asian Society of Transplantation（CAST2017）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03922
[Presentation] 分割肝移植のための機械灌流適用の検討2017
- Author(s)
  小原弘道，吉川遼，松野直徒,森戸規之，絵野沢伸，平野俊彦，古川博之
- Organizer
  日本移植学会
- Data Source
  KAKENHI-PROJECT-15H03922
[Presentation] 腎臓の機能回復を目指した復温灌流における酸素供給の有効性2017
- Author(s)
  森井　湧太，小原　弘道，松野　直徒,平野俊彦，絵野沢伸，古川博之
- Organizer
  日本移植学会
- Data Source
  KAKENHI-PROJECT-15H03922
[Presentation] 機械臓器灌流による臓器機能評価技術の新展開2017
- Author(s)
  小原弘道，松野直徒,，吉川遼，森戸規之，森井勇太，絵野沢伸，平野俊彦
- Organizer
  臓器保存生物医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15H03922
[Presentation] Ex vivo reperfusion model to evaluate availability of machine preservation for liver donated after cardiac death2017
- Author(s)
  Ryo Yoshikawa, Hiromichi Obara, Naoto Matsuno, Noriyuki Morito, Shin Enosawa, Toshihiko Hirano, Hiroyuki Furukawa
- Organizer
  15th Congress of the Asian Society of Transplantation（CAST2017）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03922
[Presentation] 体外血液再灌流モデルによる肝臓室温灌流保存法の評価2017
- Author(s)
  吉川遼，小原弘道，松野直徒,，森戸規之，吉野聡，中田智裕，中條哲也，絵野沢伸，平野俊彦，古川博之
- Organizer
  臓器保存生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-15H03922
[Presentation] 移植医療への理解と共感を広めるための市民参加型NPO法人の活動2017
- Author(s)
  松野　直徒,絵野沢伸，小原弘道，武藤眞，平野俊彦，立谷陽介，窪田基予子
- Organizer
  日本移植学会
- Data Source
  KAKENHI-PROJECT-15H03922
[Presentation] 幅広い温度域・灌流液に適用可能な機械灌流による普遍的腎機能評価指標の提案2017
- Author(s)
  脇隆，森井勇太，小原弘道，松野直徒,，絵野沢伸，吉野聡，中田智裕，中條哲也，平野俊彦，古川博之
- Organizer
  臓器保存生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-15H03922
[Presentation] Universal vascular index to predict organ quality during rewarming machine perfusion for kidney2016
- Author(s)
  Hiromichi Obara , Yuta Morii , Naoto Matsuno , Noriyuki Morito , Shin Enosawa , Toshihiko Hirano ,
- Organizer
  the 26th International Congress of The Transplantation Society
- Place of Presentation
  HongKong(Hong Kong)
- Year and Date
  2016-08-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03922
[Presentation] Effects of purification perfusate during subnormothermic machine perfusion for porcine liver donation after cardiac death2016
- Author(s)
  Hiromichi Obara , Noriyuki Morito , Naoto Matsuno , Shin Enosawa , Toshihiko Hirano , Hiroyuki
- Organizer
  the 26th International Congress of The Transplantation Society
- Place of Presentation
  HongKong(Hong Kong)
- Year and Date
  2016-08-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03922
[Presentation] 末梢血単核球感受性に基づくステロイド薬のテーラーメイド医療の可能性2013
- Author(s)
  竹内裕紀、平野俊彦、岩本整、中村有紀、河地茂行、畝崎榮、島津元秀
- Organizer
  第40回臓器保存生物医学会学術集会
- Place of Presentation
  東京 (シンポジウム)
- Year and Date
  2013-11-09
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] 末梢血単核球のステロイド感受性に基づく至適免疫抑制療法2013
- Author(s)
  竹内裕紀、平野俊彦、田中祥子、岩本整、中村有紀、今野理、木原優、横山卓剛、千葉斉一、高野公徳、虎石竜典、川口崇、奥山清、河地茂行、島津元秀、畝崎榮
- Organizer
  第3回医薬工3大学包括連携シンポジウム
- Place of Presentation
  東京
- Year and Date
  2013-12-14
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] 腎移植の短期ステロイド減量・離脱における末梢血単核細胞のステロイド感受性の有用性2013
- Author(s)
  竹内裕紀、岩本整、中村有紀、今野理、木原優、横山卓剛、千葉斉一高野公徳,虎石竜典、奥山清、菊池祐紀子, 川口崇河, 地茂行、平野俊彦,畝崎榮、島津元秀
- Organizer
  第172回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2013-11-02
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] エベロリムスの末梢血単核球細胞(PBMC)抑制効果におけるカルシニューリン阻害薬の薬力学的相互作用の検討2013
- Author(s)
  秋山晋一、竹内裕紀、田中祥子、平野俊彦、虎石竜典、岩本整、中村有紀、今野理、木原優、千葉斉一、横山卓剛、高野公徳、川口崇、奥山清、河地茂行、島津元秀、畝崎榮
- Organizer
  第23回医療薬学会年会
- Place of Presentation
  仙台
- Year and Date
  2013-09-21
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] 腎移植患者の末梢血単核細胞のステロイド感受性とステロイド短期減量・離脱成績との関係2013
- Author(s)
  竹内裕紀、菊池祐紀子、岩本整、中村有紀、今野理、木原優、千葉斉一横山卓剛、高野公徳,虎石竜典、奥山清、河地茂行、平野俊彦、畝崎榮、島津元秀
- Organizer
  第49回日本移植学会
- Place of Presentation
  京都
- Year and Date
  2013-09-06
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] カルシニューリン阻害薬によるステロイド感受性増強作用―移植前後におけるIC50値の比較およびinvitro実験結果より-2012
- Author(s)
  竹内裕紀、菊池祐紀子、平野俊彦、岩本整、中村有紀、今野理、城島嘉麿、木原優、横山卓剛、虎石竜典、川口崇、河地茂行、奥山清、畝崎榮、島津元秀
- Organizer
  第48回日本移植学会
- Place of Presentation
  名古屋
- Year and Date
  2012-09-22
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] 腎移植患者末梢血リンパ球のステロイド感受性に及ぼすカルシニューリン阻害剤の影響2012
- Author(s)
  グリミル・ムヒタル、竹内裕紀、岩本整、中村有紀、畝崎榮、平野俊彦、島津元秀
- Organizer
  第170回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] カルシニューリン阻害薬によるステロイド感受性増強作用2012
- Author(s)
  竹内裕紀、曽我朗子、グリミルムヒタル、平野俊彦、岩本整、中村有紀、濱耕一郎、片山宏章、今野理、城島嘉麿、横山卓剛、木原優、虎石竜典、川口崇、奥山清、島津元秀、畝崎榮
- Organizer
  第2 回医薬工3 大学包括連携推進シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] 腎移植患者における末梢血リンパ球のコルチゾール高感受性に基づく至適カルシニューリン阻害薬の選択2012
- Author(s)
  グリミル・ムヒタル、竹内裕紀、畝崎榮、平野俊彦、島津元秀
- Organizer
  第33回日本臨床薬理学会.
- Place of Presentation
  沖縄
- Year and Date
  2012-11-29
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] カルシニューリン阻害薬によるステロイド感受性増強作用2012
- Author(s)
  竹内裕紀、曽我朗子、岩本整、片山宏章、平野俊彦、中村有紀、濱耕一郎、今野理、横山卓剛、木原優、虎石竜典、川口崇,奥山清、畝崎榮、島津元秀
- Organizer
  第2回医薬工3大学包括連携推進シンポジウム
- Place of Presentation
  東京
- Year and Date
  2012-03-10
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] カルシニューリン阻害薬のリンパ球ステロイド感受性に対する増強効果2011
- Author(s)
  竹内裕紀、曽我朗子、片山宏章、平野俊彦、畝崎榮、島津元秀
- Organizer
  第38回日本臓器保存生物医学会学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22590145
[Presentation] 臓器移植医療における薬学の役割2011
- Author(s)
  平野俊彦
- Organizer
  第38回日本臓器保存生物医学会学術集会
- Place of Presentation
  仙台(招待講演)
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-22590145
[Presentation] カルシニューリン阻害薬のリンパ球ステロイド感受性に対する増強効果2011
- Author(s)
  竹内裕紀,曽我朗子,片山宏章,平野俊彦,岩本整、中村有紀、濱耕一郎、今野理、横山卓剛、木原優、虎石竜典、川口崇,奥山清、畝崎榮、島津元秀
- Organizer
  第38回臓器保存生物医学会学術集会
- Place of Presentation
  仙台
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] 腎移植患者におけるステロイド離脱の指標としての末梢血リンパ球のコルチゾール感受性2010
- Author(s)
  グリミルムヒタル、岩本整、葦沢龍人、竹内裕紀、畝崎榮、平野俊彦、島津元秀
- Organizer
  第46回日本移植学会
- Year and Date
  2010-10-19
- Data Source
  KAKENHI-PROJECT-20590159
[Presentation] 腎移植患者における内因性コルチゾールのリンパ球感受性に基づく早期ステロイド減量・離脱の可能性2010
- Author(s)
  秋月宗剛, 竹内裕紀, 平野俊彦, 松野直徒, 木原優, 今野理, 城島嘉麿, 赤司勲, 濱耕一郎, 中村有紀, 岩本整, 葦澤龍人, 川口崇, 虎石竜典, 奥山清, 長尾桓, 畝崎榮
- Organizer
  第130回日本薬学会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20590159
[Presentation] 腎移植患者におけるステロイド離脱の指標としての末梢血リンパ球のコルチゾール感受性2010
- Author(s)
  グリミル・ムヒタル, 岩本整, 葦沢龍人, 竹内裕紀, 畝崎榮, 平野俊彦, 島津元秀
- Organizer
  第46回日本移植学会
- Place of Presentation
  新潟
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-20590159
[Presentation] 腎移植患者のステロイド減量・離脱におけるステロイドのPBMC感受性の有用性2010
- Author(s)
  竹内裕紀、グリミルムヒタル、岩本整、中村有紀、濱耕一郎、虎石竜典、平野俊彦、秋月宗剛、川口崇、畝崎榮、島津元秀
- Organizer
  第37回臓器保存生物医学会学術集会
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-20590159
[Presentation] 腎移植患者における末梢血リンパ球のコルチゾール感受性に基づく至適免疫抑制の選択2010
- Author(s)
  グリミル・ムヒタル, 竹内裕紀, 岩本整, 葦沢龍人, 畝崎榮, 平野俊彦, 島津元秀
- Organizer
  第37回臓器保存生物医学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-20590159
[Presentation] 腎移植患者における内因性コルチゾールのリンパ球感受性に基づく早期ステロイド減量・離脱の可能性2010
- Author(s)
  秋月宗剛、竹内裕紀、平野俊彦、松野直徒、木原優、今野理、城島嘉麿、赤司勲、濱耕一郎、中村有紀、岩本整、葦澤龍人、川口崇、虎石竜典、奥山清、長尾桓、畝崎榮
- Organizer
  第130回日本薬学会
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20590159
[Presentation] タクロリムス療法下の腎移植患者における末梢血リンパ球のコルチゾール感受性とその臨床的意義2010
- Author(s)
  グリミルムヒタル, 岩本整, 葦澤龍人, 島津元秀, 平野俊彦, 秋月綜剛, 竹内裕紀, 畝崎榮
- Organizer
  第165回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2010-06-05
- Data Source
  KAKENHI-PROJECT-20590159
[Presentation] タクロリムス療法下の腎移植患者における末梢血リンパ球のコルチゾール感受性とその臨床的意義2010
- Author(s)
  グリミルムヒタル、秋月綜剛、竹内裕紀、畝崎榮、松野直徒、長尾桓、平野俊彦
- Organizer
  第130回日本薬学会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20590159
[Presentation] 腎移植患者のステロイド減量・離脱におけるステロイドのPBMC感受性の有用性2010
- Author(s)
  竹内裕紀, グリミルムヒタル, 岩本整, 中村有紀, 濱耕一郎, 虎石竜典, 平野俊彦, 秋月宗剛, 川口崇, 畝崎榮, 島津元秀
- Organizer
  第37回臓器保存生物医学会学術集会
- Place of Presentation
  新潟
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-20590159
[Presentation] Differences of Lymphocyte Sensitivities to Steroids between Patients Administered Tacrolimus and Cyclosporine after Renal Transplantation2010
- Author(s)
  Hironori Takeuchi, Muhetaer Gulimire, Sougo Akizuki, Koichiro Hama, Yuki Nakamura, Hitoshi Iwamoto, Tatsuto Ashizawa, Tatsunori Toraishi, Sachiko Tanaka, Takashi Kawaguchi, Kiyoshi Okuyama, Takao Akashi, Toshihiko Hirano, Motohide Shimazu, Sakae Unezaki
- Organizer
  70th International Congress of International Pharmaceutical Federation
- Place of Presentation
  Lisbon, Portogal
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-20590159
[Presentation] 腎移植患者がステロイドを安全に減量・離脱するための薬力学的指標の検討2009
- Author(s)
  谷口雅彦、竹内裕紀、畝崎榮、虎石竜典、奥山清、明石貴雄、松野直徒、木原優、今野理、城島嘉麿、平良眞一郎、濱耕一郎、中村有紀、岩本整、葦沢龍人、長尾桓、平野俊彦
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590162
[Presentation] 腎移植におけるステロイド減量、離脱のためのCOR IC50の有用性2009
- Author(s)
  松野直徒, 竹内裕紀, 平野俊彦, 浦島良典, 川瀬友則, 寺岡慧
- Organizer
  第45回日本移植学会総会
- Place of Presentation
  東京
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20590159
[Presentation] 重症筋無力症患者末梢血T細胞におけるP糖タンパク質機能およびTh1/Th2バランスに免疫抑制薬物療法が及ぼす影響2009
- Author(s)
  山田奈緒、中島佳奈子、田中祥子、増田眞之、井戸信博、大塚敬男、西田昌史、内海裕也、平野俊彦
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590162
[Presentation] 腎移植の薬物療法管理/ステロイドを安全に減量する検査方法の開発2009
- Author(s)
  谷口雅彦、竹内裕紀、畝崎榮、奥山清、明石貴雄、松野直徒、木原優、今野理、城島嘉麿、平良眞一郎、濱耕一郎、中村有紀、岩本整、葦沢龍人、長尾桓、平野俊彦
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590162
[Presentation] 腎移植におけるステロイド減量、離脱のためのCOR IC50の有用性2009
- Author(s)
  松野直徒、竹内裕紀、平野俊彦、浦島良典、川瀬友則、寺岡慧
- Organizer
  第45回日本移植学会総会
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-20590159
[Presentation] 重症筋無力症患者B細胞の活性化に免疫抑制薬が及ぼす影響2008
- Author(s)
  森崎裕哉、山田奈緒、中島佳奈子、田中祥子、増田眞之、井戸信博、大塚敬男、西田昌史、平野俊彦、内海裕也
- Organizer
  第29回日本臨床薬理学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590162
[Presentation] possibility of steroid withdrawal based on lymphocyte sensitivity of endogenous cortisol in renal transplant recipients2008
- Author(s)
  Hironori Takeuchi, Naoto Matsuno, Toshihiko Hirano, Abuduxukuer Mijiti, Takeshi Nagao, Tatsunori Toraishi, Kiyoshi Okuyama, Takao Akashi, Sakae Unezaki
- Organizer
  68th International Congress of lnternational Pharmaceutical Federation
- Year and Date
  2008-08-30
- Data Source
  KAKENHI-PROJECT-20590159
[Presentation] 重症筋無力症患者末梢血T細胞におけるP糖タンパク質機能にステロイド治療が及ぼす影響2008
- Author(s)
  田中祥子、山田奈緒、中島佳奈子、増田眞之、井戸信博、大塚敬男、西田昌史、平野俊彦、内海裕也
- Organizer
  第29回日本臨床薬理学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590162
[Presentation] 重症筋無力症患者の末梢血単核細胞におけるP糖タンパク質機能および制御性T細胞が治療に及ぼす影響2008
- Author(s)
  山田奈緒、中島佳奈子、田中祥子、増田眞之、井戸信博、大塚敬男、西田昌史、内海裕也、平野俊彦
- Organizer
  医療薬学フォーラム2008/第16回クリニカルファーマシーシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590162
[Presentation] 末梢血単核球のステロイド感受性に基づく至適免疫抑制療法
- Author(s)
  竹内裕紀　平野俊彦　田中祥子　岩本整　中村有紀　今野理　木原優　横山卓剛　千葉斉一　高野公徳　虎石竜典川口崇　奥山清　河地茂行　島津元秀　畝崎榮
- Organizer
  第３回医薬工３大学包括連携シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] 腎移植患者における末梢血リンパ球のコルチゾール高感受性に基づく至適カルシニューリン阻害薬の選択
- Author(s)
  グリミル・ムヒタル，竹内　裕紀，畝崎榮，平野俊彦，島津元秀
- Organizer
  第33回日本臨床薬理学会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] 腎移植患者末梢血リンパ球のステロイド感受性に及ぼすカルシニュリン阻害剤の影響
- Author(s)
  グリミル・ムヒタル，竹内裕紀，岩本整，中村有紀，畝崎榮，平野俊彦，島津元秀
- Organizer
  第170回東京医科大学医学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] カルシニューリン阻害薬によるステロイド感受性増強作用 ―移植前後におけるIC50値の比較およびinvitro実験結果より－
- Author(s)
  竹内裕紀，菊池祐紀子，平野俊彦，岩本整、中村有紀、今野理、城島嘉麿、木原優、横山卓剛、虎石竜典、川口崇，河地茂行、奥山清、畝崎榮、島津元秀
- Organizer
  第48回日本移植学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] Synergistic Effect of Steroid Sensitivity to Peripheral Blood Mononuclear Cells on Calcineurin Inhibitors
- Author(s)
  Hironori Takeuchi, Hitoshi Iwamoto, Yuki Nakamura, Osamu Konno, Yu Kihara, Naokazu Chiba, Takayoshi Yokoyama, Kiminori Takano, Tatsunori Toraishi, Kiyoshi Okuyama, Sakae Unezaki, Toshihiko Hirano, Shigeyuki Kawachi, Motohide Shimazu
- Organizer
  The 13 th Congress of Asian Society of Transplantation
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-23590201
[Presentation] 末梢血単核球感受性に基づくステロイド薬のテーラーメイド医療の可能性
- Author(s)
  竹内裕紀　平野俊彦　岩本整　中村有紀　河地茂行　畝崎榮　島津元秀
- Organizer
  第40回臓器保存生物医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590201

1. MATSUNO Naoto (00231598)

# of Collaborated Projects: 3 results

# of Collaborated Products: 30 results
2. TAKEUCHI Hironori (20439912)

# of Collaborated Projects: 2 results

# of Collaborated Products: 37 results
3. OKA Kitaro (40057336)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. NAGAO Takeshi (90143487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. UNEZAKI Sakae (00408684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
6. KOZAKI Masami (30096309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YOSHIDA Masaharu (60146537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. obara Hiromichi (80305424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
9. Enosawa Shin (40232962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
10. 島津元秀 (70124948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
11. 杉山健太郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hirano Toshihiko 平野 俊彦

HIRANO Toshihiko 平野 俊彦

HIRANO TOSHIHIKO 平野 俊彦

Research Projects

Research Products

Co-Researchers

Effects of insulin on pharmacodynamics of immunosuppressive drugs in human peripheral T lymphocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of Liver flow dynamics for organ preservation, recovery and assessment to develop future medical devices

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synergistic Effects of Calcineurin Inhibitors and Steroids on Steroid Sensitivity of Peripheral Blood Mononuclear Cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of several antibiotics on proliferation and regulatory T cell frequency in human lymphocytes stimulated with superantigenPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Steroid Withdrawal Based on Lymphocyte Sensitivity to Endogenous Steroid in Renal Transplant Recipients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms for resistance to immunosuppressive drugs in human lymphocytes stimulated with bacterial superantigen and the effects of antibiotics.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Relationship between sensitivities of peripheral blood-mononuclear cells to immunosuppressive drugs and Staphylococcus aureus infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Influence of serum lipids on lymphocyte sensitivity to immunosuppressive drugs and its clinical implication in patients with nephrosis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on individual immunosuppressive therapy based on peripheral-blood lymphocyte-sensitivity to immunosuppressive drugs and the mechanisms on drug resistancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Selection of steroids in accordance with lymphocyte abilities and improvement of clinical outcomes of kidney transplantation.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research for natural compounds inducing apoptosis in leukemia cells without foxicity on normal immune cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunosuppressive therapy based on lymphocyte sensitivity in renal transplant patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Improvement of assay method of glucocorticoids and its application to the immunosuppressive drug therapy of renal transplantation.

Principal Investigator

Hirano Toshihiko 平野俊彦

HIRANO Toshihiko 平野俊彦

HIRANO TOSHIHIKO 平野俊彦