Nagamine Takeaki 長嶺竹明

… Alternative Names

NAGAMINE Takeaki 長嶺竹明

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Researcher Number	90180520
Other IDs
Affiliation (Current)	2025: 高崎健康福祉大学, 健康福祉学部, 客員教授 2025: 群馬大学, その他部局等, 名誉教授
Affiliation (based on the past Project Information) *help	2015 – 2016: 群馬大学, その他部局等, 名誉教授 2015: 群馬大学, 保健学研究科, 名誉教授 2015: 群馬大学, 名誉教授 2012 – 2014: 群馬大学, 保健学研究科, 教授 2011: 群馬大学, 大学院・保健学研究科, 教授 … More 2009 – 2010: Gunma University, 医学部, 教授 2004 – 2005: 群馬大学, 医学部, 教授 1998: Gunma University School of Medicine, Professor, 医学部, 教授 1996 – 1997: 群馬大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Radiation science / Gastroenterology Except Principal Investigator General medical chemistry / Medical Physics and Radiological Technology / Laboratory medicine
Keywords	Principal Investigator 赤血球 / α fetoprotein / biotinidase / cultured hepatoma cell line / fucoidan / αフェトピロテイン / 培養肝癌細胞 / microPIXE / 細胞周期 / αフェトプロテイン … More / ビオチニダーゼ / 培養肝細胞 / フコイダン / インターフェロン / 貧血 / ３剤併用療法 / リバビリン / Ｃ型慢性肝炎 / 大気マイクロＰＩＸＥ / 肝硬変 / Mg / 大気マイクロPIXE / 腎性貧血 / カリウム / 鉄 / 瀉血療法 / C型慢性肝炎 / マイクロPIXE / 透析 / 大気マイクロPIXE,貧血 … More Except Principal Investigator Zinc / Hepatitis C / Interferon / Metallothionein / C型慢性肝炎 / C型肝炎ウィルス / メタロチオネインmRNA / 亜鉛 / C型肝炎 / インターフェロン / メタロチオネイン / bortezomib / ボルテゾミブ / 微量元素 / マイクロPIXE / 多発性骨髄腫 / ＥＬＩＳＡ / メタロチオネイン-III / メタロチオネイン-I/II / ELISA / メンケス病 / ウィルソン病 / 前立腺がん / メタロチオネイン-Ⅲ / メタロチオネイン-Ⅰ/Ⅱ Less

Measurement of trace elements with micro-PIXE method in myeloma cells and development of novel drugs
- Principal Investigator
  
  Murakami Hirokazu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical Physics and Radiological Technology
- Research Institution
  Gunma University
Study of determination of metallothionein (MT) - 1/2 and MT-3 in human and experimental animal with ELISA
- Principal Investigator
  
  Nakazato Kyoumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Gunma University
Analysis of anemia associated with patients treated by interfern and ribavirinPrincipal Investigator
- Principal Investigator
  
  NAGAMINE Takeaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Gunma University
Analysis of elemental distribution in erythrocytes using in-air-micro PIXE and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  NAGAMINE Takeaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Gunma University
Study on the biotinidase competitive inhibition constant in liver cancer, and its control by a sugar chainPrincipal Investigator
- Principal Investigator
  
  NAGAMINE Takeaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Gunma University
Treatment for chronic hepatitis C with metallothionein induction by IFN
- Principal Investigator
  
  MORI Masatomo
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Gunma University

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2005 Other

All Journal Article Presentation

[Journal Article] Elemental changes of erythrocytes in patients with chronic liver disease caused by hepatitis C virus2016
- Author(s)
  Takeaki Nagamine, Hiroki Kikuchi, Yoshiharu Tokita, Taito Akutsu, Masashi Kohka , Takahiro Satoh , Tomihiro Kamiya
- Journal Title
  
  I J PIXE
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591749
[Journal Article] Primary leptomeningeal B-cell lymphoma with normal pressure hydrocephalus at diagnosis2015
- Author(s)
  Chiaki Suto, Hirokazu Murakami, Yoshino Kobayashi, Takeaki Nagamine, Takayuki Saitoh, Tetsuhiro Kasamatsu, Hatsue Ogawara, Masami Murakami.
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 56 Issue: 12 Pages: 2441-2446
- DOI
  10.11406/rinketsu.56.2441
- NAID
  130005116919
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460720
[Journal Article] Determination of the serum metallothionein (MT) 1/2 concentration in patients with Wilson's disease and Menkes disease2014
- Author(s)
  Kyoumi Nakazato, Satoru Tomioka, Katsuyuki Nakajima, Hidetoshi Saito, Mihoko Kato, Tsukasa Kodaira, Shin-ichi Yatsuzuka, Younosuke Shimomura, Tomoko Hiroki, Kahoko Motoyama, Hiroko Kodama, Takeaki Nagamine
- Journal Title
  
  Journal of Trace Elements in Medicine and Biology
  
  Volume: 28 Pages: 441-447
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460672
[Journal Article] Stress-induced Biomarkers in Liver with Non-alcohol Fatty Liver Diseases and Non-alcohol Steatohepatitis2014
- Author(s)
  Hiromi Ono, Akira Tanaka, Kyoumi Nakazato, Yutaka Hasegawa, Ke Ih Kim, Soo Ryang Kim, Katsuyuki Nakajima, Takeaki Nagamine
- Journal Title
  
  THE KITAKANTO MEDICAL JOURNAL
  
  Volume: 64 Pages: 13-22
- NAID
  130003393784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460672
[Journal Article] Development of a High Sensitivity ELISA for the Assay of Metallothionein.2013
- Author(s)
  Nagamine T, Nakajima K.
- Journal Title
  
  Ｃｕｒｒ　Ｐｈａｒｍ　Ｂｉｏｔｅｃｈｎｏｌ
  
  Volume: １４ Pages: 247-431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591749
[Journal Article] Significance of Metallothionein Expression in Liver Disease2013
- Author(s)
  Nagamine T, Nakajima K.
- Journal Title
  
  Ｃｕｒｒ　Ｐｈａｒｍ　Ｂｉｏｔｅｃｈｎｏｌ
  
  Volume: 14 Pages: 420-426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591749
[Journal Article] The anti-apoptotic effect of fucoxanthin on carbon tetrachloride-induced hepatotoxicity.2013
- Author(s)
  Kaneko M, Nagamine T, Nakazato K, Mori M
- Journal Title
  
  J Toxicol Sci
  
  Volume: 38 Issue: 1 Pages: 115-126
- DOI
  10.1093/toxsci/kfu050
- NAID
  10031138732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591749
[Journal Article] Analysis of trace elements in erythrocytes obtained from dialysis patients using in-air micro PIXE2010
- Author(s)
  H.Kikuchi, T.Nagamine, Y.Tokita, T Satoh, T Kamiya.
- Journal Title
  
  T Kamiya. JAEA Review
  
  Pages: 88-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591545
[Journal Article] In-air micro-PIXE analysis for metal elements in rats hepatocytes treated with fucoidan2009
- Author(s)
  H. TAKADA, T. NAGAMINE, Y. TOKITA, M. OIKAWA, H. SATOH, T. KAMIYA, K. ARAKAWA and M. IHA.
- Journal Title
  
  International Journal of PIXE
  
  Volume: 19 Pages: 47-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591545
[Journal Article] Preparation of human erythrocytes for in-air micro-PIXE analysis2009
- Author(s)
  Y Tokita, H kikuchi, T Nagamine, T Satoh, T Kamiya, K Arakawa.
- Journal Title
  
  JAEA Review
  
  Pages: 117-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591545
[Journal Article] Interferon-alpha-induced changes in metallothionein expression in liver biopsies from patients with chronic hepatitis C2005
- Author(s)
  T.Nagamine, et al.
- Journal Title
  
  Can J Gastroenterology 19
  
  Pages: 481-486
- Data Source
  KAKENHI-PROJECT-16590575
[Journal Article] Interferon-alpha-induced changes metallothionein expression in liver biopsies from patients with chronic hepatitis C2005
- Author(s)
  T Nagamine
- Journal Title
  
  Can J Gastroenterology 19
  
  Pages: 481-486
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590575
[Journal Article] Interferon-alpha-induced changes in metallothionein expression in liver biopsies from patients with chronic hepatitis C2005
- Author(s)
  T Nagamine
- Journal Title
  
  Can J Gastroenterology 19
  
  Pages: 481-486
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590575
[Presentation] 気Micro-PIXE法を用いた多発性骨髄腫細胞内微量元素の動態解析2017
- Author(s)
  笠松哲光、長嶋友海、長嶺竹明、村上博和、山田尚人、喜多村茜、佐藤隆博、江夏昌志、神谷富裕
- Organizer
  第1回QST高崎研シンポジウム
- Place of Presentation
  高崎
- Year and Date
  2017-01-26
- Data Source
  KAKENHI-PROJECT-26460720
[Presentation] 気Micro-PIXE法を用いた多発性骨髄腫細胞内微量元素の動態解析2016
- Author(s)
  長嶋友海、笠松哲光、長嶋友海、長嶺竹明、村上博和、山田尚人、喜多村茜、佐藤隆博、江夏昌志、神谷富裕
- Organizer
  第63回　北関東医学会総会
- Place of Presentation
  前橋
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-26460720
[Presentation] ＬＥＣラット（ｗｉｌｓｏｎ病）及びＭａｃｕｌａｒマウス（Ｍｅｎｋｅｓ病）臓器におけるメタロチオネイン（MT）受容体ＭｅｇａｌｉｎとＭＴ-1/2並びにＭＴ-3の局在の検討2015
- Author(s)
  中里享美、齋藤秀俊、加藤美穂子、小平司、宮川誠、廣木伴子、児玉浩子、近藤宏樹、岡村隆行、中嶋克行、長嶺竹明
- Organizer
  メタルバイオサイエンス研究会2015
- Place of Presentation
  名古屋国際センター　ホール（愛知県名古屋市）
- Year and Date
  2015-08-27
- Data Source
  KAKENHI-PROJECT-25460672
[Presentation] ウィルソン病患者およびＬＥＣラット検体のメタロチオネイン濃度の測定とその生化学的性状2015
- Author(s)
  齋藤秀俊、加藤美穂子、宮川誠、廣木伴子、児玉浩子、近藤宏樹、岡村隆行、町田哲夫、中嶋清美、角野博之、村上正巳、中里享美、中嶋克行、長嶺竹明
- Organizer
  メタルバイオサイエンス研究会2015
- Place of Presentation
  名古屋国際センター　ホール（愛知県名古屋市）
- Year and Date
  2015-08-27
- Data Source
  KAKENHI-PROJECT-25460672
[Presentation] ウィルソン病患者およびＬＥＣラット検体のＭｅｔａｌｌｏｔｈｉｏｎｅｉｎ濃度の測定2015
- Author(s)
  齋藤秀俊、加藤美穂子、宮川誠、廣木伴子、児玉浩子、近藤宏樹、岡村隆行、町田哲夫、中嶋清美、角野博之、村上正巳、中里享美、中嶋克行、長嶺竹明
- Organizer
  第26回日本微量元素学会　学術集会
- Place of Presentation
  北海道大学（北海道札幌市）
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-25460672
[Presentation] LECラット肝臓、腎臓、脳におけるメタロチオネイン（MT）受容体ＭｅｇａｌｉｎとＭＴ-1/2並びにＭＴ-3の局在の検討2015
- Author(s)
  中里享美、齋藤秀俊、加藤美穂子、小平司、宮川誠、廣木伴子、児玉浩子、近藤宏樹、岡村隆行、中嶋克行、長嶺竹明
- Organizer
  第26回日本微量元素学会　学術集会
- Place of Presentation
  北海道大学（北海道札幌市）
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-25460672
[Presentation] 前立腺組織におけるメタロチオネイン（MT）発現と血中及び尿中MT濃度の比較検討2014
- Author(s)
  中里享美、中嶋克行、熊坂文成、加瀬嘉明、山中英壽、黒澤功、齋藤秀俊、小平司、長嶺竹明
- Organizer
  第25回日本微量元素学会　学術集会
- Place of Presentation
  岡山大学創立五十周年記念館（岡山県岡山市）
- Year and Date
  2014-07-03
- Data Source
  KAKENHI-PROJECT-25460672
[Presentation] マイクロＰＩＸＥによる赤血球元素分析の臨床応用2013
- Author(s)
  富岡智, 長嶺竹明、佐藤博隆、江夏昌志、神谷冨裕
- Organizer
  29回ＰＩＸＥシンポジウム
- Place of Presentation
  敦賀市
- Data Source
  KAKENHI-PROJECT-24591749
[Presentation] 大気マイクロPIXE による貧血の病態解明2012
- Author(s)
  富岡智，阿久津泰斗，長嶺竹明，佐藤博隆，江夏昌志，神谷富裕
- Organizer
  ２８回ＰＩＸＥシンポジウム
- Place of Presentation
  東工大蔵前会館（東京）
- Data Source
  KAKENHI-PROJECT-24591749
[Presentation] Microelement of erythrocytes in dialysis patients analyzed by in-air micro-PIXE2011
- Author(s)
  T Nagamine, T Akutsu, Y Tokita, K Nakazato, T Sato, T Kamiya.
- Organizer
  7th international Symposium on bio-PIXE
- Place of Presentation
  Sendai
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PROJECT-21591545
[Presentation] Microelements of the erythrocytes in dialysis patients analyzed by inair micro-PIXE2011
- Author(s)
  長嶺竹明
- Organizer
  7^<th> International Symposium on Bi-PIXE
- Place of Presentation
  高平桜ホール(仙台市)
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PROJECT-21591545
[Presentation] 大気マイクロPIXEを用いた肝臓病患者の貧血の解析2011
- Author(s)
  長嶺竹明, 阿久津泰斗, 佐藤隆博, 江夏昌志, 神谷富祐
- Organizer
  第6回高崎量子応用研究シンポジウム
- Place of Presentation
  高崎市
- Data Source
  KAKENHI-PROJECT-21591545
[Presentation] 大気micro-PIXEを用いた透析患者の赤血球分析。2010
- Author(s)
  菊地弘記, 時田佳治, 長嶺竹明, 佐藤隆博, 神谷富裕
- Organizer
  第27回PIXEシンポジウム
- Place of Presentation
  宇治市
- Year and Date
  2010-11-18
- Data Source
  KAKENHI-PROJECT-21591545
[Presentation] ヒト赤血球を用いた大気マイクロPIXE測定用試料の作成2009
- Author(s)
  時田佳治, 菊地弘記, 長嶺竹明
- Organizer
  第26回PIXEシンポジウム
- Place of Presentation
  千葉市
- Year and Date
  2009-11-19
- Data Source
  KAKENHI-PROJECT-21591545
[Presentation] ヒト赤血球を用いた大気マイクロPIXE測定試料の作製2009
- Author(s)
  時田佳時、長嶺竹明, ほか
- Organizer
  第26回PIXEジンポジウム
- Place of Presentation
  千葉市
- Year and Date
  2009-11-19
- Data Source
  KAKENHI-PROJECT-21591545
[Presentation] ヒト赤血球を用いた大気マイクロPIXE測定試料の作成2009
- Author(s)
  時田佳治, 菊地弘記, 長嶺竹明, 佐藤隆博, 神谷富祐, 荒川和夫
- Place of Presentation
  高崎市
- Data Source
  KAKENHI-PROJECT-21591545
[Presentation] メンケス病モデル動物マクラマウスにおける血中並びに組織中のＭＴ1/2濃度について
- Author(s)
  富岡智、中里享美、中嶋克行、小平司、児玉浩子、長嶺竹明
- Organizer
  メタルバイオサイエンス研究会2013
- Place of Presentation
  静岡県立大学（静岡県静岡市）
- Data Source
  KAKENHI-PROJECT-25460672
[Presentation] Analysis of erythrocyte element in chronic hepatitis C patients treated with interferon and ribavirin by in-air microPIXE
- Author(s)
  Nagamine Takeaki, Tomioka Satoru, Saito Takahiro, Koka Masashi, Kamiya Tomihiro
- Organizer
  ＩＣＮＭＴＡ2014
- Place of Presentation
  Padova, Italy,
- Year and Date
  2014-07-07 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-24591749
[Presentation] Plasma metallothionein I/II in liver diseases
- Author(s)
  Takeaki Nagamine, Satoru Tomioka, Kyoumi Nakazato, Katsuyuki Nakajima, Hiroko Kodama
- Organizer
  第１０回国際微量元素学会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-25460672
[Presentation] Enzyme-linked immunosorbent assay for metallothionein-III in humans and experimental animals
- Author(s)
  Katsuyuki Nakajima, Hidetoshi Saito, Tsukasa Kodaira, Kyoumi Nakazato, Satoru Tomioka, Takeaki Nagamine
- Organizer
  第１０回国際微量元素学会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-25460672
[Presentation] 大気マイクロPIXEによる慢性肝疾患の赤血球内元素分布の解析
- Author(s)
  長嶺竹明、笠松　哲光、村上博和、江夏昌志、山田尚人、喜多村茜、佐藤隆博、横山彰人、大久保猛、石井保行、神谷冨祐、後藤祥子、世良耕一郎
- Organizer
  ３０回ＰＩＸＥシンポジウム
- Place of Presentation
  岩手県盛岡市
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-24591749
[Presentation] インターフェロンと亜鉛・メタロチオネイン
- Author(s)
  長嶺竹明
- Organizer
  第7回近畿亜鉛栄養治療研究会
- Place of Presentation
  大阪市
- Invited
- Data Source
  KAKENHI-PROJECT-24591749

1. Nakazato Kyoumi (80241909)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
2. NAKAJIMA Katsuyuki (10444051)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
3. Murakami Hirokazu (40166260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. MORI Masatomo (80174382)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SATOH Masao (20045743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SUZUKI Keiji (40008313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HAYAKAWA Koh (80192277)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 神谷富裕 (70370385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 齋藤貴之 (80375542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Nagamine Takeaki 長嶺 竹明

NAGAMINE Takeaki 長嶺 竹明

Research Projects

Research Products

Co-Researchers

Measurement of trace elements with micro-PIXE method in myeloma cells and development of novel drugs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of determination of metallothionein (MT) - 1/2 and MT-3 in human and experimental animal with ELISA

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of anemia associated with patients treated by interfern and ribavirinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of elemental distribution in erythrocytes using in-air-micro PIXE and its clinical applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the biotinidase competitive inhibition constant in liver cancer, and its control by a sugar chainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Treatment for chronic hepatitis C with metallothionein induction by IFN

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Elemental changes of erythrocytes in patients with chronic liver disease caused by hepatitis C virus2016

Author(s)

Journal Title

Data Source

[Journal Article] Primary leptomeningeal B-cell lymphoma with normal pressure hydrocephalus at diagnosis2015

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[Journal Article] Determination of the serum metallothionein (MT) 1/2 concentration in patients with Wilson's disease and Menkes disease2014

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[Journal Article] Stress-induced Biomarkers in Liver with Non-alcohol Fatty Liver Diseases and Non-alcohol Steatohepatitis2014

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[Journal Article] Development of a High Sensitivity ELISA for the Assay of Metallothionein.2013

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[Journal Article] Significance of Metallothionein Expression in Liver Disease2013

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[Journal Article] The anti-apoptotic effect of fucoxanthin on carbon tetrachloride-induced hepatotoxicity.2013

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[Journal Article] Analysis of trace elements in erythrocytes obtained from dialysis patients using in-air micro PIXE2010

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Nagamine Takeaki 長嶺竹明

NAGAMINE Takeaki 長嶺竹明