INOUE Naoki 井上直樹

… Alternative Names

井上直樹イノウエナオキ

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Researcher Number	90183186
Other IDs	https://orcid.org/0000-0002-9245-4979
Affiliation (Current)	2025: 岐阜薬科大学, 薬学部, 客員共同研究員
Affiliation (based on the past Project Information) *help	2021: 岐阜薬科大学, 薬学部, 客員共同研究員 2013 – 2020: 岐阜薬科大学, 薬学部, 教授 2012: 国立感染症研究所, ウイルス第1部, 室長 2010 – 2012: 国立感染症研究所, ウイルス第一部, 室長 2004 – 2006: 国立感染症研究所, ウイルス第1部, 室長 1995: 国立予防衛生研究所, ウイルス第1部, 主任研究官 1994 – 1995: 国立予防衛生研究所, ウイルス第一部, 主任研究官
Review Section/Research Field	Principal Investigator Virology / Basic Section 49060:Virology-related / Biological Sciences / Virology Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Virology
Keywords	Principal Investigator サイトメガロウイルス / 感染防御 / モルモット / 感染 / 水痘帯状疱疹ウイルス / 動物モデル / 先天性感染 / 中和抗体 / 細胞指向性 / 糖蛋白 … More / 宿主遺伝子 / 薬剤耐性 / 宿主免疫 / 細胞死 / 胎盤 / 細胞死阻害 / 抗体依存性貪食 / Fcγ受容体 / 免疫回避 / アミノ酸変異 / BAC / 中和 / 感染機序 / ペンタマー / ワクチン / signal responses of host cells / cell-cell fusion / pseudotypes / genotypes / cytomegalovirus / varicella-zoster virus / glycoproteins / herpesviruses / 水泡性口内炎ウイルス / ヒトヘルペスウイルス8 / 宿主応答 / 細胞融合 / シュードタイプ / 遺伝子多型 / ヘルペスウイルス / 転写活性化因子 / カプシド / 抗ウイルス薬 / アデノウイルス / 遺伝子トラップ / 細胞トロピズム / レトロウイルスベクター / サイトロメガウイルス / DNA複製 / リポーター細胞 / 水痘帯萢疹ウイルス / ヒトヘルペスウイルス / アシクロビル / 抗ウイルス剤 / 点突然変異 / 転写活性化 / ウイルスベクター / origin結合蛋白 / origin / DNA複製開始機構 / ヒトヘルペスウイルス-6 … More Except Principal Investigator ウイルス / ナノ粒子 / リポソーム / Protein transport / Epithelial cells / M protein / Mictotubules / Budding polarity / Tryptase clara / Tropism / Sendai virus / 微小管 / 細胞骨格系 / M蛋白 / M遺伝子 / 細胞極性 / F1-R株 / ウイルス出芽極性 / センダイウイルス Less

Host immune responses against congenital cytomegalovirus infection and viral immune evasion mechanismsPrincipal Investigator
- Principal Investigator
  
  Inoue Naoki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Gifu Pharmaceutical University
Development of versatile antiviral medicines using advanced decoy particles for topical mucosal formulations
- Principal Investigator
  
  Tahara Kohei
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Gifu Pharmaceutical University
Studies on the structure and function of Pentamer, the cell tropism determinant of cytomegalovirus, and on its induction of protective immunityPrincipal Investigator
- Principal Investigator
  
  Inoue Naoki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Gifu Pharmaceutical University
Analyses of effects of novel anti-herpesvirus compounds identified in screening on viral replication and gene expressionPrincipal Investigator
- Principal Investigator
  
  Inoue Naoki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Gifu Pharmaceutical University
Study on cytomegalovirus: cell tropism, pathogenesis, and induction of protective antibodies.Principal Investigator
- Principal Investigator
  
  INOUE Naoki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
抗ヘルペスウイルス剤耐性の迅速検索用細胞株の樹立と複製開始に特異的な阻害剤の創製Principal Investigator
- Principal Investigator
  
  井上直樹
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Infectious Diseases
ヒトサイトメガロウイルス感染に必須な宿主細胞遺伝子の遺伝子トラップ法による同定Principal Investigator
- Principal Investigator
  
  井上直樹
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
Study on molecular mechanisms of herpesvirus entry into host cellsPrincipal Investigator
- Principal Investigator
  
  INOUE Naoki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
遺伝子治療用ベクター開発を目標としたヒトヘルペスウイルス-6DNA複製機構の研究Principal Investigator
- Principal Investigator
  
  井上直樹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  国立予防衛生研究所
Identification of Determinants for Tropism of Sendai virus
- Principal Investigator
  
  TASHIRO Masato
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Institute of Health

[Journal Article] Suppression of human trophoblast syncytialization by human cytomegalovirus infection2022
- Author(s)
  Mimura Nobuko、Nagamatsu Takeshi、Morita Kazuki、Taguchi Ayumi、Toya Takashi、Kumasawa Keiichi、Iriyama Takayuki、Kawana Kei、Inoue Naoki、Fujii Tomoyuki、Osuga Yutaka
- Journal Title
  
  Placenta
  
  Volume: 117 Pages: 200-208
- DOI
  10.1016/j.placenta.2021.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07578, KAKENHI-PROJECT-21K09442
[Journal Article] The Guinea pig cytomegalovirus GP119.1 gene encodes an IgG‐binding glycoprotein that is incorporated into the virion2021
- Author(s)
  Majima Ryuichi、Koshizuka Tetsuo、Inoue Naoki
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 65 Issue: 1 Pages: 28-39
- DOI
  10.1111/1348-0421.12867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07578
[Journal Article] ICTV Virus Taxonomy Profile: Herpesviridae 20212021
- Author(s)
  Gatherer D, Depledge DP, Hartley CA, Szpara ML, Vaz PK, Benko; M, Brandt CR, Bryant NA, Dastjerdi A, Doszpoly A, Gompels UA, Inoue N, Jarosinski KW, Kaul R, Lacoste V, Norberg P, Origgi FC, Orton RJ, Pellett PE, Schmid DS, Spatz SJ, Stewart JP, Trimpert J, Waltzek TB, Davison AJ
- Journal Title
  
  Journal of General Virology
  
  Volume: 102 Issue: 10 Pages: 001673-001673
- DOI
  10.1099/jgv.0.001673
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07578
[Journal Article] Characterization of a thiourea derivative that targets viral transactivators of cytomegalovirus and herpes simplex virus type 12021
- Author(s)
  Kondo Hiroki、Koshizuka Tetsuo、Majima Ryuichi、Takahashi Keita、Ishioka Ken、Suzutani Tatsuo、Inoue Naoki
- Journal Title
  
  Antiviral Research
  
  Volume: 196 Pages: 105207-105207
- DOI
  10.1016/j.antiviral.2021.105207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07578
[Journal Article] Enhancement of guinea pig cytomegalovirus infection by two endogenously expressed components of the pentameric glycoprotein complex in epithelial cells2020
- Author(s)
  Okumura Misaki、Matsuura-Miura Miku、Makino Reina、Miura Takuya、Noguchi Kazuma、Majima Ryuichi、Koshizuka Tetsuo、Inoue Naoki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 8530-8530
- DOI
  10.1038/s41598-020-65545-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07578
[Journal Article] Clinical Diagnostic Testing for Human Cytomegalovirus Infections2020
- Author(s)
  Razonable Raymund R、Inoue Naoki、Pinninti Swetha G、Boppana Suresh B、Lazzarotto Tiziana、Gabrielli Liliana、Simonazzi Giuliana、Pellett Philip E、Schmid D Scott
- Journal Title
  
  The Journal of Infectious Diseases
  
  Volume: 221 Issue: Supplement_1 Pages: S74-S85
- DOI
  10.1093/infdis/jiz601
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07578
[Journal Article] The Carboxyl-Terminal Penta-Peptide Repeats of Major Royal Jelly Protein 3 Enhance Cell Proliferation2020
- Author(s)
  Minegaki Naho、Koshizuka Tetsuo、Nishina Saeka、Kondo Hiroki、Takahashi Keita、Sugiyama Tsuyoshi、Inoue Naoki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 12 Pages: 1911-1916
- DOI
  10.1248/bpb.b20-00607
- NAID
  130007948721
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-12-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07578
[Journal Article] Identification and functional analyses of a cell-death inhibitor encoded by guinea pig cytomegalovirus gp38.1 in cell culture and in animals2020
- Author(s)
  Noguchi Kazuma、Majima Ryuichi、Takahashi Keita、Iwase Yoshihiko、Yamada Souichi、Satoh Keisuke、Koshizuka Tetsuo、Inoue Naoki
- Journal Title
  
  Journal of General Virology
  
  Volume: 101 Issue: 12 Pages: 1270-1279
- DOI
  10.1099/jgv.0.001493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07578
[Journal Article] Activation of c-Jun by human cytomegalovirus UL42 through JNK activation2020
- Author(s)
  Koshizuka Tetsuo、Inoue Naoki
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 5 Pages: e0232635-e0232635
- DOI
  10.1371/journal.pone.0232635
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07578, KAKENHI-PROJECT-20K08844
[Journal Article] Evaluation of the indirect and IgM‐capture anti‐human cytomegalovirus IgM ELISA methods as confirmed by cytomegalovirus IgG avidity2019
- Author(s)
  Ikuta Kazufumi、Koshizuka Tetsuo、Kanno Ryoko、Inoue Naoki、Kubo Takahiko、Koyano Shin、Suzutani Tatsuo
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 63 Issue: 5 Pages: 172-178
- DOI
  10.1111/1348-0421.12683
- NAID
  40021927513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07578, KAKENHI-PROJECT-17H04346
[Journal Article] Characterization of phenyl pyrimidine derivatives that inhibit cytomegalovirus immediate-early gene expression2018
- Author(s)
  Yamada Koh-Hei、Majima Ryuichi、Yamaguchi Toyofumi、Inoue Naoki
- Journal Title
  
  Antiviral Chemistry and Chemotherapy
  
  Volume: 26 Pages: 1-7
- DOI
  10.1177/2040206618763193
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08815
[Journal Article] Differences in the effects of mutations in GP131, a guinea pig cytomegalovirus homologue of pentameric complex component UL130, on macrophage and epithelial cell infection2018
- Author(s)
  Miura Takuya、Makino Reina、Yamada Kouhei、Matsuura Miku、Okumura Misaki、Yamada Souichi、Watanabe Shinji、Inoue Naoki
- Journal Title
  
  Journal of General Virology
  
  Volume: 99 Issue: 10 Pages: 1425-1431
- DOI
  10.1099/jgv.0.001137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08815
[Journal Article] Analysis of relationships between polymorphisms in the genes encoding the pentameric complex and neutralization of clinical cytomegalovirus isolates2018
- Author(s)
  Kobayashi Ryo、Abe Mao、Oguri Kohdai、Torikai Masaharu、Nishimura Tomohiro、Mori Hiroaki、Koshizuka Tetsuo、Inoue Naoki
- Journal Title
  
  Vaccine
  
  Volume: 36 Issue: 40 Pages: 5983-5989
- DOI
  10.1016/j.vaccine.2018.08.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10185, KAKENHI-PROJECT-16K08815
[Journal Article] Vaccine Development for Cytomegalovirus2018
- Author(s)
  Inoue Naoki、Abe Mao、Kobayashi Ryo、Yamada Souichi
- Journal Title
  
  Adv Exp Med Biol.
  
  Volume: 1045 Pages: 271-296
- DOI
  10.1007/978-981-10-7230-7_13
- ISBN
  9789811072291, 9789811072307
- Data Source
  KAKENHI-PROJECT-16K08815
[Journal Article] Roles of GP33, a guinea pig cytomegalovirus-encoded G protein-coupled receptor homolog, in cellular signaling, viral growth and inflammation in vitro and in vivo2018
- Author(s)
  Takeda Miei、Watanabe Shinji、Katano Harutaka、Noguchi Kazuma、Sato Yuko、Kojima Sayaka、Miura Takuya、Majima Ryuichi、Yamada Souichi、Inoue Naoki
- Journal Title
  
  PLOS Pathogens
  
  Volume: 14 Issue: 12 Pages: e1007487-e1007487
- DOI
  10.1371/journal.ppat.1007487
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08815
[Journal Article] Effects of cationic liposomes with stearylamine against virus infection2018
- Author(s)
  Tahara Kohei、Kobayashi Manami、Yoshida Satoko、Onodera Risako、Inoue Naoki、Takeuchi Hirofumi
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 543 Issue: 1-2 Pages: 311-317
- DOI
  10.1016/j.ijpharm.2018.04.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08815, KAKENHI-PROJECT-18K06753
[Journal Article] Characterization of an anti-varicella-zoster virus compound that targets the portal protein encoded by ORF542017
- Author(s)
  Yasui Ruka、Yoshida Chinatsu、Yamaguchi Toyofumi、Inoue Naoki
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 61 Issue: 9 Pages: 398-402
- DOI
  10.1111/1348-0421.12507
- NAID
  40021326058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08815
[Journal Article] Characterization of a thienylcarboxamide derivative that inhibits transactivation functions of cytomegalovirus IE2 and varicella zoster virus IE622017
- Author(s)
  Majima R, Shindo K, Yamaguchi T, Inoue N
- Journal Title
  
  Antiviral Res
  
  Volume: 140 Pages: 142-150
- DOI
  10.1016/j.antiviral.2017.01.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08815
[Journal Article] サイトメガロウイルス感染症2017
- Author(s)
  古谷野伸、井上直樹
- Journal Title
  
  臨床と微生物
  
  Volume: 44 Pages: 63-68
- Data Source
  KAKENHI-PROJECT-16K08815
[Journal Article] Congenital cytomegalovirus in Japan: More than 2 year follow up of infected newborns2017
- Author(s)
  Koyano Shin、Morioka Ichiro、Oka Akira、Moriuchi Hiroyuki、Asano Kimisato、Ito Yushi、Yoshikawa Tetsushi、Yamada Hideto、Suzutani Tatsuo、Inoue Naoki、the Japanese Congenital Cytomegalovirus Study Group
- Journal Title
  
  Pediatrics International
  
  Volume: 60 Issue: 1 Pages: 57-62
- DOI
  10.1111/ped.13433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08815
[Journal Article] Newborn Congenital Cytomegalovirus Screening Based on Clinical Manifestations and Evaluation of DNA-based Assays for In Vitro Diagnostics2017
- Author(s)
  Fujii Tomoyuki、Oka Akira、Morioka Ichiro、Moriuchi Hiroyuki、Koyano Shin、Yamada Hideto、Saito Shigeru、Sameshima Hiroshi、Nagamatsu Takeshi、Tsuchida Shinya、Inoue Naoki
- Journal Title
  
  The Pediatric Infectious Disease Journal
  
  Volume: 36 Issue: 10 Pages: 942-946
- DOI
  10.1097/inf.0000000000001630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08815
[Journal Article] An ex vivo culture model for placental cytomegalovirus infection using slices of guinea pig placental tissue.2016
- Author(s)
  Yamada S, Katano H, Sato Y, Fukuchi S, Hashimoto K, Inoue N
- Journal Title
  
  Placenta
  
  Volume: 37 Pages: 85-88
- DOI
  10.1016/j.placenta.2015.10.016
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460578, KAKENHI-PROJECT-26860857, KAKENHI-PROJECT-16K08815
[Journal Article] Neurological outcomes in symptomatic congenital cytomegalovirus-infected infants after introduction of newborn urine screening and antiviral treatment.2016
- Author(s)
  Nishida K, Morioka I, Nakamachi Y, Kobayashi Y, Imanishi T, Kawano S, Iwatani S, Koda T, Deguchi M, Tanimura K, Yamashita D, Nibu KI, Funakoshi T, Ohashi M, Inoue N, Iijima K, Yamada H.
- Journal Title
  
  Brain & Dev
  
  Volume: 38 Pages: 209-216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460578
[Journal Article] 新しい抗ヘルペスウイルス薬2015
- Author(s)
  井上直樹、安井瑠香、馬島龍一、山田晃平
- Journal Title
  
  臨床とウイルス
  
  Volume: 43 Pages: 285-295
- Data Source
  KAKENHI-PROJECT-25460578
[Journal Article] Low total IgM values and high cytomegalovirus loads in the blood of newborns with symptomatic congenital cytomegalovirus infection.2015
- Author(s)
  Kobayashi Y, Morioka I, Koda T, Nakamachi Y, Okazaki Y, Noguchi Y, Ogi M, Chikahira M, Tanimura K, Ebina Y, Funakoshi T, Ohashi M, Iijima K, Inoue N, Kawano S, Yamada H
- Journal Title
  
  J Perinatal Med
  
  Volume: 43 Issue: 2 Pages: 239-243
- DOI
  10.1515/jpm-2014-0071
- NAID
  120005740370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460578, KAKENHI-PROJECT-26461632
[Journal Article] Molecular and virological evidence of viral activation from chromosomally integrated human herpesvirus 6A in a patient with X-linked severe combined immunodeficiency2014
- Author(s)
  Endo A, Watanabe K, Ohye T, Suzuki K, Matsubara T, Shimizu N, Kurahashi H, Yoshikawa T, Katano H, Inoue N, Imai K, Takagi M, Morio T, Mizutani S
- Journal Title
  
  Clin Infect Dis
  
  Volume: 59 Issue: 4 Pages: 545-548
- DOI
  10.1093/cid/ciu323
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390085, KAKENHI-PROJECT-25460578, KAKENHI-PROJECT-26293244, KAKENHI-PROJECT-26670171
[Journal Article] The IgG avidity value for the prediction of congenital cytomegalovirus infection in a prospective cohort study2014
- Author(s)
  Ebina Y, Minematsu T, Sonoyama A, Morioka I, Inoue N, Tairaku S, Nagamata S, Tanimura K,Morizane M, Deguchi M, Yamada H
- Journal Title
  
  J Perinat Med
  
  Volume: - Issue: 6 Pages: 755-759
- DOI
  10.1515/jpm-2013-0333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592403, KAKENHI-PROJECT-25460578
[Journal Article] Aberrant fetal macrophage/microglial reaction to cytomegalovirus infection.2014
- Author(s)
  akiko Sakao-Suzuki Hideya Kawasaki Taisuke Akamatsu, Shiori Meguro, Hiroaki Miyajima Toshihide Iwashita, Yoshihiro Tsutsui, Naoki Inoue5 & Isao Kosugi.
- Journal Title
  
  Annals of Clinical and Translational Neurology
  
  Volume: 1(8) Issue: 8 Pages: 570-588
- DOI
  10.1002/acn3.88
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25282164, KAKENHI-PROJECT-25460578, KAKENHI-PROJECT-26460487
[Journal Article] Evidence for human herpesvirus-6B infection of regulatory T-cells in acute systemic lymphadenitis in an immunocompetent adult with the drug reaction with eosinophilia and systemic symptoms syndrome: A case report.2014
- Author(s)
  Mine S, Suzuki K, Sato Y, Fukumoto H, Kataoka M, Inoue N, Ohbayashi C, Hasegawa H, Sata T, Fukayama M,Katano H
- Journal Title
  
  J Clin Virol
  
  Volume: 61 Issue: 3 Pages: 448-452
- DOI
  10.1016/j.jcv.2014.08.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460578
[Journal Article] Guinea pig cytomegalovirus GP129/131/133, homologs of human cytomegalovirus UL128/130/131A, are required for infection of monocytes and macrophages2014
- Author(s)
  Yamada S, Fukuchi S, Hashimoto K, Fukui Y, Tsuda M, Kataoka M, Katano H, Inoue N
- Journal Title
  
  J Gen Virol
  
  Volume: 95 Issue: 6 Pages: 1376-1382
- DOI
  10.1099/vir.0.064527-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460578
[Journal Article] The presence of antibodies against the AD2 epitope of cytomegalovirus glycoprotein B is associated with acute rejection after renal transplantation.2014
- Author(s)
  Ishibashi K, Tokumoto T, Shirakawa H, Oguro T, Yanagida T, Takahashi N, Nomiya M, Haga N, Aikawa K, Tanabe K, Inoue N, Kojima Y, Suzutani T
- Journal Title
  
  Microbiol Immunol
  
  Volume: 58 Issue: 1 Pages: 72-75
- DOI
  10.1111/1348-0421.12112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460578
[Journal Article] Unusually extensive disseminated herpes zoster with multiple ulcer formation in a methotrexate-treated rheumatoid arthritis patient.2014
- Author(s)
  Kakuta R, Okata U, Funakoshi T, Fujio Y, Inoue N, Takahashi S, Amagai M, Ohyama M.
- Journal Title
  
  J. Dermatology
  
  Volume: 41 Issue: 2 Pages: 181-182
- DOI
  10.1111/1346-8138.12377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460578
[Journal Article] The highly conserved human cytomegalovirus UL136 ORF generates multiple Golgi-localizing protein isoforms through differential translation initiation2014
- Author(s)
  Liao H, Lee JH, Kondo R, Katata M, Imadome K, Miyado K, Inoue N, Fujiwara S, Nakamura H
- Journal Title
  
  Virus Res
  
  Volume: 179 Pages: 241-6
- DOI
  10.1016/j.virusres.2013.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21112006, KAKENHI-PROJECT-24591616, KAKENHI-PROJECT-25460578
[Journal Article] Idiopathic intrauterine growth restriction caused by cytomegalovirus infection and associated placental pathology.2014
- Author(s)
  Pereira L, Petitt M, Fong A, Tsuge M, Tabata T, Fang-Hoover J, Maidji E, Zydek M, Zhou Y, Inoue N, Logahvi S, Pepkowitz S, Ogunyemi D
- Journal Title
  
  J Infec Dis
  
  Volume: 209 Issue: 10 Pages: 1573-1584
- DOI
  10.1093/infdis/jiu019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460578
[Journal Article] Effects of immunization of pregnant guinea pigs with guinea pig cytomegalovirus glycoprotein B on viral spread in the placenta.2013
- Author(s)
  Hashimoto K, Yamada S, Katano H, Fukuchi S, Sato Y, Kato M, Yamaguchi T, Moriishi K, Inoue N
- Journal Title
  
  Vaccine
  
  Volume: 31 Issue: 31 Pages: 3199-205
- DOI
  10.1016/j.vaccine.2013.04.078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590426, KAKENHI-PROJECT-25460578
[Journal Article] Quantitative Evaluation of Ventricular Dilatation using Computed Tomography in Infants with Congenital Cytomegalovirus Infection.2013
- Author(s)
  Matsuo K
- Journal Title
  
  Brain & Development.
  
  Volume: in press Issue: 1 Pages: 10-15
- DOI
  10.1016/j.braindev.2012.12.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591076, KAKENHI-PROJECT-23592403, KAKENHI-PROJECT-25460578, KAKENHI-PROJECT-25860860
[Journal Article] Human cytomegalovirus induces apoptosis in neural stem/progenitor cells derived from induced pluripotent stem cells by generating mitochondrial dysfunction and endoplasmic reticulum stress2013
- Author(s)
  Nakamura H, Imadome K, et al.(他10名)
- Journal Title
  
  Herpesviridae
  
  Volume: 4(1) Issue: 1 Pages: 2-2
- DOI
  10.1186/2042-4280-4-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591375, KAKENHI-PROJECT-24591616, KAKENHI-PROJECT-25460578
[Journal Article] Polymorphisms in TLR-2 are associated with congenital cytomegalovirus (CMV) infection, but not with congenital CMV disease2013
- Author(s)
  Taniguchi R, Koyano S, Suzutani T, Goishi K, Ito Y, Morioka I, Oka A, Nakamura H, Yamada H,Igarashi T, Inoue N
- Journal Title
  
  Int J Infect Dis
  
  Volume: 17 Issue: 12 Pages: 1092-1097
- DOI
  10.1016/j.ijid.2013.06.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592403, KAKENHI-PROJECT-25460578
[Journal Article] Detection of human herpesviruses in the cerebrospinal fluid from patients diagnosed with or suspected of having progressive multifocal leukoencephalopathy2013
- Author(s)
  K. Nakamichi, N. Inoue, T. Shimokawa, I. Kurane, C.K. Lim, M. Saijo
- Journal Title
  
  BMC Neurology
  
  Volume: 13(200) Issue: 1 Pages: 200-200
- DOI
  10.1186/1471-2377-13-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700334, KAKENHI-PROJECT-24591591, KAKENHI-PROJECT-25460578
[Journal Article] Cytomegalovirus (CMV) glycoprotein H-based serological analysis in Japanese healthy pregnant women, and in neonates with congenital CMV infection and their mothers.2013
- Author(s)
  14. Ikuta K, Minematsu T, Inoue N, Kubo T, Asano K, Ishibashi K, Imamura T, Nakai H, Yoshikawa T, Moriuchi H, Fujiwara S, Koyano S, Suzutani T
- Journal Title
  
  J Clin Virol
  
  Volume: 58 Issue: 2 Pages: 474-478
- DOI
  10.1016/j.jcv.2013.07.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460578, KAKENHI-PROJECT-25870580
[Journal Article] Cytomegalovirus impairs CTB-induced lymph- angiogenesis and vascular remodeling in an in vivo human placentation model.2012
- Author(s)
  Tabata T, Petitt M, Fang-Hoover J, Rivera J, Nozawa N, Shiboski S, Inoue N, Pereira L
- Journal Title
  
  Am. J. Pathol.
  
  Volume: 181 Issue: 5 Pages: 1540-59
- DOI
  10.1016/j.ajpath.2012.08.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590426
[Journal Article] novel real-time PCR method for the determination and quantification of each cytomegalovirus (CMV) gH- subtype in clinical samples2012
- Author(s)
  Ikuta K, Ishioka K, Sato Y, Imamura T, Asano K, Koyano S, Inoue N, Suzutani T
- Journal Title
  
  J. Clin. Microbiol
  
  Volume: 50 Issue: 2 Pages: 499-501
- DOI
  10.1128/jcm.06032-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590426
[Journal Article] The lack of antibodies against the AD2 epitope of cytomegalovirus (CMV) glycol- protein B (gB) is associated with CMV disease after renal transplantation in recipients having gH serotypes same as their donors.2011
- Author(s)
  Ishibashi K, Tokumoto T, Shirakawa H, Hashimoto K, Ikuta K, Kushida N, Yanagida T, Shishido K, Aikawa K, Toma H, Inoue N, Yamaguchi O, Tanabe K, Suzutani T
- Journal Title
  
  Transplant. Infect. Dis.
  
  Volume: 13 Issue: 3 Pages: 318-28
- DOI
  10.1111/j.1399-3062.2010.00563.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590426
[Journal Article] Re-evaluation of guinea pig cytomegalovirus complete genome sequence.2011
- Author(s)
  Kanai K, Yamada S, Yamamoto Y, Fukui Y, Kurane I, Inoue N
- Journal Title
  
  J. Gen. Virol.
  
  Volume: 92 Issue: 5 Pages: 1005-20
- DOI
  10.1099/vir.0.027789-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590426
[Journal Article] Herpesvirus 8 genoprevalence in people at disparate risks of Kaposi's sarcoma.2007
- Author(s)
  N.Kumar, K.McLean, N.Inoue, D.R.Moles, C.Scully, S.R.Porter, C.G.Teo.
- Journal Title
  
  J.Med.Virol. 79
  
  Pages: 52-59
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390138
[Journal Article] Real-time PCR assay using specimens on filter disks as a template for detection of cytomegalovirus in urine specimens.2007
- Author(s)
  N.Nozawa, S.Koyano, Y.Yamamoto, Y.Inami, I.Kurane, N.Inoue.
- Journal Title
  
  J.Clin.Microbiol. 45
  
  Pages: 1305-1307
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390138
[Journal Article] HCMVのゲノム構造と遺伝子機能2006
- Author(s)
  井上直樹
- Journal Title
  
  日本臨床 64・3
  
  Pages: 377-385
- Data Source
  KAKENHI-PROJECT-16390138
[Journal Article] Generation of a reporter cell line for the detection of infectious varicella-zoster virus and its applications for antiviral studies.2006
- Author(s)
  G Q.Wang, T.Suzutani, Y.Yamamoto, Y.Fukui, N.Nozawa, D.S.Schmid, I.Kurane, N.Inoue.
- Journal Title
  
  Antimicrob Agents Chemother. 50
  
  Pages: 3142-3145
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390138
[Journal Article] Newly identified human herpesviruses.2006
- Author(s)
  L.T.Krug LT, C.G.Teo, K.Tanaka-Taya, N.Inoue.
- Journal Title
  
  Emerging Infectious Diseases of the 21^<st> Century.((Eds) IW Fong, K Alibek)(Springer, NY.)
  
  Pages: 197-276
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390138
[Journal Article] HCMVのゲノム構造と遺伝子機能2006
- Author(s)
  井上直樹
- Journal Title
  
  日本臨床 64・3
  
  Pages: 377-385
- Data Source
  KAKENHI-PROJECT-16659122
[Journal Article] HCMVのゲノム構造と遺伝子機能2006
- Author(s)
  井上直樹, 野澤直樹
- Journal Title
  
  日本臨床 64・3
  
  Pages: 377-385
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390138
[Journal Article] HCMVのゲノム構造と遺伝子機能2006
- Author(s)
  井上直樹
- Journal Title
  
  日本臨床 64・3
  
  Pages: 377-385
- Data Source
  KAKENHI-PROJECT-16017312
[Journal Article] CMVの先天性感染機構2006
- Author(s)
  野澤直樹, 井上直樹
- Journal Title
  
  日本臨床 64・3
  
  Pages: 446-450
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390138
[Journal Article] Higher prevalence of human herpesvirus 8 DNA sequence and specific IgG antibodies in patients with pemphigus in China.2005
- Author(s)
  G.Wang, H.Xu, Y.Wang, X.Gao, Y.Zhao, C.He, N.Inoue, H.D.Chen.
- Journal Title
  
  J.Am.Acad.Dermatol. 52
  
  Pages: 46-467
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390138
[Journal Article] The impact of viral interferon regulatory factor-1 expression on responsiveness to interferon alpha and the production of infectious human herpesvirus 8 by BCBL-1 cells.2004
- Author(s)
  V.Pozharskaya, L.L.Weakland, J.C.Zimring, L.T.Krug, E.R.Unger, A.Neisch, H.Joshi, T.Kroll T, N.Inoue, M.K.Offermann.
- Journal Title
  
  J.Virol. 78
  
  Pages: 6621-6635
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390138
[Journal Article] Comparison of serologic responses between Kaposi's sarcoma-positive and-negative men who were seropositive for both human herpesvirus 8 and human immunodeficiency virus.2004
- Author(s)
  N.Inoue
- Journal Title
  
  Journal of Medical Virology 74
  
  Pages: 202-206
- Data Source
  KAKENHI-PROJECT-16017312
[Journal Article] Inhibition of infection and replication of human herpesvirus 8 by interferon-alpha and phosphonoformic acid in microvascular endothelial cells.2004
- Author(s)
  L.T.Krug, V.P.Pozharskaya, Y.Yu, N.Inoue, M.K.Offermann.
- Journal Title
  
  J.Virol. 78
  
  Pages: 8359-8371
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390138
[Journal Article] Association between outcomes of renal transplantation and antibody responses to cytomegalovirus strain-specific glycoprotein H epitopes.
- Author(s)
  K.Ishibashi, T.Tokumoto, K.Tanabe, H.Shirakawa, K.Hashimoto, N.Kushida, T.Yanagida, N.Inoue, O.Yamaguchi, H.Toma, T.Suzutani.
- Journal Title
  
  Clin.Infec.Dis. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390138
[Presentation] 抗ヘルペス薬の臨床的課題と新規薬剤探索2022
- Author(s)
  井上直樹
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] モルモット胎盤由来上皮細胞株におけるモルモットサイトメガロウイルスの感染性と宿主遺伝子発現の相関解析2022
- Author(s)
  長野愛里香, 小栗(竹田)美瑛, 髙橋圭太, 腰塚哲朗, 井上直樹
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] サイトメガロウイルス糖蛋白五量体による細胞指向性とウイルス遺伝子発現の抑制2021
- Author(s)
  井上直樹
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] サイトメガロウイルスワクチンの評価マーカーとしての抗体依存性細胞貪食に対する測定系構築および解析2021
- Author(s)
  山口佳祐, 髙橋圭太, 馬島龍一, 石山貴皓, 腰塚哲朗, 井上直樹
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] 抗ヘルペスウイルス化合物147B3作用機序の解明2021
- Author(s)
  近藤紘生, 腰塚哲朗,石岡賢, 錫谷達夫,髙橋圭太,井上直樹
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] GPCMV BACに導入した9kbの欠失領域が個体での感染に与える影響とその領域にコードされる遺伝子産物2021
- Author(s)
  岩瀬慶彦, 馬島龍一, 野口和真, 佐藤啓介, 小林祐希, 石山貴皓, 高橋圭太, 山口佳祐, 増田幸奈, 腰塚哲朗, 井上直樹
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] サイトメガロウイルス糖蛋白質Bの中和と型別に関与するAD2領域を用いた血清学的検討2020
- Author(s)
  野間早織，井上直樹
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2020
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] モルモットサイトメガロウイルスに対する抗体依存性細胞貪食の測定系構築2020
- Author(s)
  山口佳祐，高橋圭太，馬島龍一，腰塚哲朗，井上直樹
- Organizer
  第32回日本薬学会微生物シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] モルモットサイトメガロウイルスGP119.1のIgG結合機能解析2020
- Author(s)
  馬島龍一，腰塚哲朗，井上直樹
- Organizer
  第32回日本薬学会微生物シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] モルモットにおけるサイトメガロウイルス感染動態とサイトカイン産生の解析2020
- Author(s)
  小島さやか，山口佳祐，井上直樹
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2020
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] モルモットサイトメガロウイルスに対する抗体依存性免疫応答：モルモットFcγ受容体の解析2020
- Author(s)
  小河原瑛彦，馬島龍一，髙橋圭太，腰塚哲朗，井上直樹
- Organizer
  第32回日本薬学会微生物シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] 抗CMV薬のスクリーニングにより同定した化合物147B3の作用機序の検討2020
- Author(s)
  江坂里奈，井上直樹，腰塚哲朗
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2020
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] サイトメガロウイルス感染に対するワクチンの必要性、その前臨床ならびに臨床開発の状況と問題点2020
- Author(s)
  井上直樹
- Organizer
  第61回日本臨床ウイルス学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] ヒトサイトメガロウイルスの「五量体」を構成する糖タンパク質群を発現する細胞を抗原とした中和抗体誘導能の簡便な比較評価2019
- Author(s)
  大林洋絵、古賀悟、長野愛里香、奥村晃弘、小栗弘大、安部真央、腰塚哲朗、井上直樹
- Organizer
  第56回日本細菌学会中部支部総会
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] 細胞指向性を決定する複合体の構成成分であるGP131とGP133の共発現によるモルモットサイトメガロウイルス感染の亢進に関する研究2019
- Author(s)
  奥村美紗貴，牧野怜奈，三浦（松浦）未来，井上直樹
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] サイトメガロウイルスに対するワクチン候補抗原の至適化を目的としたヒト型抗体のスクリーニング系構築2019
- Author(s)
  古賀悟，小栗弘大，竹腰正隆，腰塚哲朗，井上直樹
- Organizer
  第23回日本ワクチン学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] モルモットサイトメガロウイルスがコードする細胞死抑制タンパクgp38.1の同定と培養細胞および動物個体における機能の解析2019
- Author(s)
  野口和真、馬島龍一、岩瀬慶彦、山田壮一、腰塚哲朗、井上直樹
- Organizer
  野口和真、馬島龍一、岩瀬慶彦、山田壮一、腰塚哲朗、井上直樹
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] サイトメガロウイルスの感染効率に影響する宿主因子とウイルス多型の解析2019
- Author(s)
  長島和希，小林稜，小栗弘大，腰塚哲朗，井上直樹
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07578
[Presentation] Roles of GP133, a guinea pig CMV homolog of GPCRs, in viral growth and inflammation in pregnant animals．2018
- Author(s)
  Kazuma Noguchi, Miei Takeda, Harutaka Katano, Yuko Sato, Sayaka Kojima, Shinji Watanabe, Naoki INoue
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] エンドサイトーシスを介して上皮細胞へのサイトメガロウイルス感染効率を亢進させる蛋白群の役割の解析2018
- Author(s)
  牧野怜奈、松浦未来、三浦拓也、奥村美紗貴、山田壮一、井上直樹
- Organizer
  日本薬学会　第138年会
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] Analyses of the enhancement of guinea pig CMV infection by two components of the pentameric complex that is for cell tropisms2018
- Author(s)
  Misaki Okumura, Reina Makino, Kazuki Nagashima, Takuya Miura, Naoki Inoue
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] モルモットサイトメガロウイルス(GPCMV)における血清学検査法の確立2018
- Author(s)
  小泉諒, 渡辺真次, 奥村晃弘, 井上直樹
- Organizer
  第55回日本細菌学会中部支部総会
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] Characterization of cDNA structure and functions of guinea pig cytomegalovirus GP119.12018
- Author(s)
  Ryuichi Majima, Akihiko Ogawara, Kazuma Noguchi, Tetsuo Koshizuka, Naoki Inoue
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] Immunization of mice with syngeneic mouse cells expressing glycoproteins of guinea pig CMV to evaluate CMV vaccine antigen candidates．2017
- Author(s)
  Akihiro Okumura，Masashi Sakamoto，Miku Matsuura，Takuya Miura，Kohdai Oguri，Naoki Inoue
- Organizer
  第65回ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] Guinea pig CMV GP129/131/133,homologs of human CMV UL128/130/131A,have a difference in requirements for infection of monocytes/macrophages and epithelial cells.2017
- Author(s)
  Takuya Miura、Miku Matsuura、Masashi Sakamoto、Akihiro Okumura、Miei Takeda、Souichi Yamada、Shinji Watanabe、Kohei Yamada、Naoki Inoue
- Organizer
  The 42nd Annual International Herpesvirus Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] Guinea pig CMV infection was enhanced in epithelial cells expressing GP131 and GP133，components of the non-fibroblast tropism determinant．2017
- Author(s)
  Miku Matsuura，Takuya Miura，Reina Makino，Souichi Yamada，Naoki Inoue：
- Organizer
  第65回ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] サイトメガロウイルス感染症対策を目的としたヒト型抗体のスクリーニング系構築2017
- Author(s)
  小栗弘大、竹腰正隆、井上直樹
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部　合同学術大会2017
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] Analysis of relation between genetic polymorphisms of the pentameric complex of clinical HCMV isolates and neutralization2017
- Author(s)
  Ryo Kobayashi，Kohdai Oguri，Mao Abe，Akihiro Okumura，Hiroe Ohbayashi，Naoki Inoue
- Organizer
  第65回ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] 抗サイトメガロウイルス活性を有する 4-phenylpyrimidine 誘導体の作用機序の解析2016
- Author(s)
  山田晃平、福井良子、神道慶子、井上直樹
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2016
- Place of Presentation
  岐阜
- Year and Date
  2016-10-30
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] Structural requirements of GP131, one of the pentameric complex components of guinea pig cytomegalovirus , for cell tropisms and antigenicity.2016
- Author(s)
  Takuya Miura、Masashi Sakamoto、Yamada Souichi、Shinji Watanabe、Naoki Inoue
- Organizer
  第94回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] モルモットサイトメガロウイルスがコードするGPCRホモローグの機能解析2016
- Author(s)
  渡辺真次、三浦拓也、山田壮一、杉山剛志、井上直樹
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2016
- Place of Presentation
  岐阜
- Year and Date
  2016-10-30
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] Establishement of a reporter cell line for detection of CMV infection in epithelial cells and its use for neutralizing antibody titration.2016
- Author(s)
  Mao Abe、Ryo Kobayashi、Naoki Inoue
- Organizer
  第94回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] 水痘帯状疱疹ウイルスportalタンパクを標的とする新規抗ウイルス化合物の同定と作用機序の解析2016
- Author(s)
  安井瑠香、井上直樹
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25460578
[Presentation] Characerization of a thienylcarboxamide derivative that inhibits the transactivation function of CMV and VZV immediate-early proteins.2016
- Author(s)
  Ryuichi Majima、Keiko Shindo、Yoshiko Fukui、Toyofumi Yamaguchi、Naoki Inoue
- Organizer
  第94回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16K08815
[Presentation] The two wheels for infection control of VZV diseases: quality control of vaccine products and development of anti-VZV compounds2014
- Author(s)
  Inoue N
- Organizer
  The 39th International Herpesvirus Workshop
- Place of Presentation
  神戸国際展示場（神戸市）
- Year and Date
  2014-07-23
- Invited
- Data Source
  KAKENHI-PROJECT-25460578
[Presentation] Guinea Pig CMV GP129/131/133, Homologs of HCMV UL128/130/131A, are Required for Entry into Macrophages but not into Fibroblast and Epithelial cells2013
- Author(s)
  Kaede Hashimoto, Saki Fukuchi, Souichi Yamada, Yoshiko Fukui, Mihoko Tsuda, Michiyo Kataoka, Harutaka Katano, ○Naoki Inoue
- Organizer
  第38回国際ヘルペスウイルスワークショップ
- Place of Presentation
  米国Grand Rapids
- Data Source
  KAKENHI-PROJECT-25460578
[Presentation] モルモット妊娠動物モデルを用いたサイトメガロウイルス糖蛋白Bサブユニットワクチンの効果機序の解析2012
- Author(s)
  橋本楓、山田壮一、片野晴隆、福地早希、佐藤由子、森石恆司、井上直樹
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590426
[Presentation] モルモットサイトメガロウイルス(GPCMV)を用いた先天性感染病態の解析2012
- Author(s)
  福地早希, 山田壮一, 橋本楓, 片野晴隆, 佐藤由子, 森石恆司, 井上直樹
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590426
[Presentation] Congenital cytomegalovirus infection identified in pregnancies complicated by idiopathic intrauterine growth restriction.2012
- Author(s)
  Tabata T, Petitt M, Fang-Hoover J, Rivera J, Nozawa N, Shiboski S, Inoue N, Pereira L.
- Organizer
  4th Congenital CMV Conference & 14th International CMV/beta-herpesvirus Workshop
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-22590426
[Presentation] Immunization of pregnant guinea pigs with glycoprotein B (gB).2012
- Author(s)
  Hashimoto K, Yamada S, Fukuchi S, Katano H, Sato Y, Kato M, Moriishi K, Inoue N
- Organizer
  4th Congenital CMV Conference/the International Betaherpesvirus Workshop
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-22590426
[Presentation] A genotypic and serologic study of cytomegalovirus (CMV) reinfection in mothers and neonates with congenital CMV infection in Japan.2011
- Author(s)
  Kazufumi Ikuta, Ken Ishioka, Takashi Imamura, Kimisato Asano, Tetsushi Yoshikawa, Hiroyuki Moriuchi, Shigeyoshi Fujiwara, Takahiko Kubo, Shin Koyano, Naoki Inoue, Tatsuo Suzutani
- Organizer
  XV International Congress of Virology
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-22590426
[Presentation] モルモット感染動物モデルを用いたサイトメガロウィルスワクチン開発の基礎検討2011
- Author(s)
  橋本楓、井上直樹
- Organizer
  第15回日本ワクチン学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590426
[Presentation] Characterization of human cytomegalovirus UL136 gene product.2011
- Author(s)
  Huanan Kiao, Jung-Hyun Lee, Naoki Inoue, Kenji Miyado, Shigeyoshi Fujiwara
- Organizer
  XV International Congress of Virology
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-22590426
[Presentation] ヒトサイトメガロウイルスUL136領域に見出された新規遺伝子産物2010
- Author(s)
  廖華南、Jung-Hyun Lee, 井上直樹、宮戸健二、藤原成悦、中村浩幸
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-22590426
[Presentation] In vivoで増殖可能なGuinea pig (GPCMV)のゲノム配列の解析2010
- Author(s)
  金井亨輔、山田壮一、山本由美子、福井良子、倉根一郎、井上直樹
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-22590426
[Presentation] 新規作用メカニズムによるEHV-1感染症治療薬候補化合物の探索
- Author(s)
  岡田彩加、安井瑠香、井上直樹、大屋賢司、福士秀人
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  北海道大学（札幌市）
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-25460578
[Presentation] HHV6B の制御性 T 細胞への感染が証明された DRESS 症候群の一剖検例
- Author(s)
  峰宗太郎、鈴木高祐、佐藤由子、福本瞳、井上直樹、片岡紀代、大林千穂、長谷川秀樹、佐多徹太郎、深山正久、片野晴隆
- Organizer
  第62回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜会議センター（横浜市）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-25460578
[Presentation] A single nucleotide polymorphism in the NKG2D gene is associated with clinical outcome of congenital cytomegalovirus infection at birth.
- Author(s)
  Taniguchi R, Koyano S, Suzutani T, Goishi K, Ito Y, Morioka I, Nakamura H, Yamada H, Oka A, Inoue N
- Organizer
  The 39th International Herpesvirus Workshop
- Place of Presentation
  神戸国際展示場（神戸市）
- Year and Date
  2014-07-19 – 2014-07-23
- Data Source
  KAKENHI-PROJECT-25460578

1. TASHIRO Masato (90111343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. YAMADA Kenichirou (30150189)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. ITAMURA Shigeyuki (60203080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HARADA Shizuko (10218646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Tahara Kohei (30454325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 高山道子 (10226938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 竹内洋文 (50171616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HASHIMOTO Kaede

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. FUKUCHI Saki

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. FUKUI Yoshiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. TSUDA Mihoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TSUTSUI Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. IMADOME Kenichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. SHIMOKAWA Toshio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 倉橋浩樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 山田秀人

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 宮戸健二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 井上直和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 腰塚哲朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

INOUE Naoki 井上 直樹

井上 直樹 イノウエ ナオキ

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Host immune responses against congenital cytomegalovirus infection and viral immune evasion mechanismsPrincipal Investigator

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Development of versatile antiviral medicines using advanced decoy particles for topical mucosal formulations

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Studies on the structure and function of Pentamer, the cell tropism determinant of cytomegalovirus, and on its induction of protective immunityPrincipal Investigator

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Analyses of effects of novel anti-herpesvirus compounds identified in screening on viral replication and gene expressionPrincipal Investigator

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Study on cytomegalovirus: cell tropism, pathogenesis, and induction of protective antibodies.Principal Investigator

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抗ヘルペスウイルス剤耐性の迅速検索用細胞株の樹立と複製開始に特異的な阻害剤の創製Principal Investigator

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ヒトサイトメガロウイルス感染に必須な宿主細胞遺伝子の遺伝子トラップ法による同定Principal Investigator

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Study on molecular mechanisms of herpesvirus entry into host cellsPrincipal Investigator

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遺伝子治療用ベクター開発を目標としたヒトヘルペスウイルス-6DNA複製機構の研究Principal Investigator

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Identification of Determinants for Tropism of Sendai virus

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[Journal Article] Suppression of human trophoblast syncytialization by human cytomegalovirus infection2022

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[Journal Article] The Guinea pig cytomegalovirus GP119.1 gene encodes an IgG‐binding glycoprotein that is incorporated into the virion2021

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[Journal Article] ICTV Virus Taxonomy Profile: Herpesviridae 20212021

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INOUE Naoki 井上直樹

井上直樹イノウエナオキ