NOBUSAWA Eri 信澤枝里

… Alternative Names

Researcher Number	90183904
Other IDs
External Links
Affiliation (Current)	2022: 国立感染症研究所, インフルエンザ・呼吸器系ウイルス研究センター, 主任研究官
Affiliation (based on the past Project Information) *help	2008: Nagoya City University, 大学院医学研究科, 准教授 2007 – 2008: Nagoya City University, 大学院・医学研究科, 准教授 2002 – 2004: NAGOYA CITY UNIVERSITY, GRADUATE SCHOOL OF MEDICAL SCIENCES, ASSOCIATE PROFESSOR, 大学院・医学研究科, 助教授 1999 – 2001: NAGOYA CITY UNIVERSITY, MEDICAL SCHOOL, ASSOCIATE PROFESSOR, 医学部, 助教授 1996 – 1998: 名古屋市立大学, 医学部, 講師 … More
Review Section/Research Field	Principal Investigator Virology / Virology Except Principal Investigator Virology / Virology / Bacteriology (including Mycology)
Keywords	Principal Investigator インフルエンザウイルス / influenza virus / 血球凝集素 / レセプター / インフルエンザウィルス / receptor / H3N2 / 血球凝集素(HA) / 膜融合 / 変異許容性 … More Except Principal Investigator インフルエンザウイルス / 血球凝集素 / Influenza virus / hemagglutinin / 経鼻接種 / rCTB / rLTB / ファージディスプレイ / 抗原 / インフルエンザワクチン / ミミック抗原 / 単一抗体 / in vitro抗体作製 / in vitro発現 / Influenza Virus / monoclonal antibody / in vitro antibody synthesis / 神経病原性 / 神経 / 免疫化学 / 黒質 / レセプター / ラット / 脳細胞 / シアル酸 / neurovirulence / intranasal inoculation / neuron / immunohistochemical / substantia nigra / 粒子形成 / HA蛋白質 / ノイラミニダーゼ / 脱シアル酸反応 / GG167 / インフルエンザウィルス / virion formation / HA protein / neuraminidase / desialidation / 百日咳 / 遺伝子組み換え / ワクチン / 経鼻投与 / 粘膜アジュバント / PTA / 百日咳ワクチン / 粘膜ワクチン / アジュバント / CTB / LTB / 無毒化PTA / pertussis / wooping cough / recombinant vaccine / substituted PTA / intranasal administration / Bacillus brevis / アミノ酸変異 / 蛋白質 / 進化 / 抗原変異 / インフルエンザ / HA / ランダム変異 / アミノ酸変異地図 / amino acid change / protein / evolution / インフルエンザウイルスA型 / HAのアミノ酸配列 / レセプタ-結合構造 / レセプタ-特異性 / 部位突然変異 / レセプタ-結合領域 / シグナルペプチド / シアル酸結合部位 / Influenza a Virus / Amino Acid Sequence of Ha / Receptor Binding Site / Receptor Specificity Less

Basic analysis on the mechanism of antigenic change in influenza B viruses using bioinformaticsPrincipal Investigator
- Principal Investigator
  
  NOBUSAWA Eri
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Nagoya City University
ファージディスプレイ法によるミミック抗原の作製とインフルエンザワクチンの開発研究
- Principal Investigator
  
  NAKAJIMA Katsuhisa
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Nagoya City University
The analysis of the restriction of amino acid substitution on the hemagglutinin molecule of influenza A virus
- Principal Investigator
  
  NAKAJIMA Katsuhisa
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  NAGOYA CITY UNIVERSITY
STUDY ON THE MOLECULAR BASIS OF RECEPTOR-RECOGNITION MECHANISM BY RECENT HUMAN INFLEUNZA VIRUSESPrincipal Investigator
- Principal Investigator
  
  NOBUSAWA Eri
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  NAGOYA CITY UNIVERSITY
Potential use of recombinant pertussis vaccine for intranasal administration
- Principal Investigator
  
  KOZUKA Satoshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Chukyo Women's University
molecular basis for the virion formation of influenza virus
- Principal Investigator
  
  NAKAJIMA Katsuhisa
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Virology
- Research Institution
  Nagoya City University
STUDY ON THE NUEROVIRULENCE OF RECENT HUMAN INFLUENZA VIRUSESPrincipal Investigator
- Principal Investigator
  
  NOBUSAWA Eri
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  NAGOYA CITY UNIVERSITY
The study on the molecular basis for neurovirulence of influenza virus.
- Principal Investigator
  
  NAKAJIMA Katsuhisa
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya City University
MOLECULAR BASIS OF NOVEL RECEPTOR BINDING SPECIFICITY OF RECENT ISOLATES OF HUMAN INFLUENZA A VIRUSESPrincipal Investigator
- Principal Investigator
  
  NOBUSAWA Eri
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  NAGOYA CITY UNIVERSITY
再構成ウィルス粒子を用いた膜融合機構の解析Principal Investigator
- Principal Investigator
  
  信澤枝里
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Virology
- Research Institution
  Nagoya City University
The study of the production of human antibody in vitro expression system and recognition of epitope on the HA protein by human immune system.
- Principal Investigator
  
  NAKAJIMA Katsuhisa
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya City University
The Analysis of the Structure of Receptor Binding Site of Hemagglutin in Molecule of Influenza A Virus and of the Characteristics of Receptor.
- Principal Investigator
  
  NAKAJIMA Katsuhisa
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo

All 2008 2007 2005 2004 2003

All Journal Article Presentation

[Journal Article] Effects of single-point amino acid substitutions on the structure and function neuraminidase proteins in influenza A virus2008
- Author(s)
  Yano T, Nobusawa E , Nagy A, Nakajima S, Nakajima K
- Journal Title
  
  Microbiol Immunol 52(4)
  
  Pages: 216-223
- NAID
  10025691767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590482
[Journal Article] Comparison of epitope structures of H3HAs through protein modeling of influenza A virus hemagglutinin: mechanism for selection of antigenic variants in the presence of a monoclonal antibody2007
- Author(s)
  Nakajima S, Nakajima K, Nobusawa E, Zhao J, Tanaka S, Fukuzawa K
- Journal Title
  
  Microbiol Immunol 51(12)
  
  Pages: 1179-1187
- NAID
  10020278027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590482
[Journal Article] Accumulation of amino acid substitution promotes irreversible structural changes In the hemagglutinin of human influenza AH3 virus during evolution2005
- Author(s)
  中島捷久, 信澤枝里等
- Journal Title
  
  J.Virol (in press)
- Data Source
  KAKENHI-PROJECT-15659111
[Journal Article] Accumulation of amino acid substitution promotes irreversible structure changes in the hemagglutinin of human influenza AH3 virus during evolution2005
- Author(s)
  中島捷久, 信澤枝里等
- Journal Title
  
  J.Virol (in press)
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Influence of additional acylation site(s) of influenza B virus hemagglutinin on syncytium formation2005
- Author(s)
  Ujike M., Nakajima K., Nobusawa E.
- Journal Title
  
  Microbiol. Immun. (in press)
- NAID
  10015527889
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Influence of additional acylation site(s) of influenza B virus hemagglutinin on syncytium formation2005
- Author(s)
  中島捷久, 信澤枝里等
- Journal Title
  
  Microbiol.Immu. (in press)
- NAID
  10015527889
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Accumulation of amino acid substitution promotesirreversible structural changes in the hemagglutinin of human influenza AH3 virus during evolutio2005
- Author(s)
  Katsuhisa Nakajima, Eri Nobusawa, Alexander Nagy, Setsuko Nakajima
- Journal Title
  
  J. Virol. 79
  
  Pages: 6472-6477
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Amino-acid change on the antigenic region B1 of H3 haemagglutinin may be a trigger for the emergence of drift strain of influenza A virus2004
- Author(s)
  中島捷久, 信澤枝里等
- Journal Title
  
  Epidemiol.Infect. 132
  
  Pages: 399-406
- Data Source
  KAKENHI-PROJECT-15659111
[Journal Article] Influence of acylation sites of influenza B virus HA on fusion poreformation and dilation2004
- Author(s)
  Ujike M, Nakajima K., Nobusawa E.
- Journal Title
  
  J. Virol. 78
  
  Pages: 11536-11543
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Amino-acid change on the Antigenic region B1 of H3 hemagglutinin may be a trigger for the emergence of drift strain on influenza A virus2004
- Author(s)
  中島捷久, 信澤枝里等
- Journal Title
  
  Epidemiol.Infect 132
  
  Pages: 399-406
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Influence of acylation sites of influenza B virus HA on fusion pore formation and dilation2004
- Author(s)
  中島捷久, 信澤枝里等
- Journal Title
  
  J.Virol 78
  
  Pages: 11536-11543
- Data Source
  KAKENHI-PROJECT-15659111
[Journal Article] Influence of acylation sites of influenza B virus HA on fusion pore-formation and dilation2004
- Author(s)
  中島捷久, 信澤枝里等
- Journal Title
  
  J.Virol. 78
  
  Pages: 11536-11543
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Amino-acid change on the antigenic region B1 of H3 haemagglutinin may be a trigger for the emergence of drift strain of influenza A virus2004
- Author(s)
  Sato, K., Morishita, T., Nobusawa, E., Tonegawa, K.Sakae, K., Nakajima, S., Nakajima, K.
- Journal Title
  
  Epidemiol. Infect 132
  
  Pages: 399-406
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370104
[Journal Article] Restriction of amino acid change in influenza A virus H3HA: comparison of amino acid changes observed in nature and in vitro2003
- Author(s)
  Nakajima K, Nobusawa E, Tonegawa K, Nakajima S
- Journal Title
  
  J. Virol 77
  
  Pages: 10088-10098
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370104
[Presentation] B 型インフルエンザウイルスHA 上のアミノ酸変異の蓄積2008
- Author(s)
  信澤枝里
- Organizer
  日本ウイルス学会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-19590482
[Presentation] The Tolerance of Influenza B Virus HA To Amino Acid Changes2008
- Author(s)
  Nobusawa Eri
- Organizer
  Options for the Control of Influenza VI
- Place of Presentation
  Metro Toronto Convention Centre, Toronto, Canada
- Year and Date
  2008-06-18
- Data Source
  KAKENHI-PROJECT-19590482
[Presentation] B型インフルエンザウイルスHA上のアミノ酸変異の蓄積2008
- Author(s)
  信澤枝里
- Organizer
  日本ウイルス学会
- Place of Presentation
  岡山コンベンションセンター
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-19590482

1. NAKAJIMA Katsuhisa (40012778)

# of Collaborated Projects: 7 results

# of Collaborated Products: 12 results
2. NAKJIMA Setsuko (80124402)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
3. IIDUKA Narusi (30222821)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KOZUKA Satoshi (40117817)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TAKAHASHI Mituo (70299543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NOBUSAWA Eri 信澤 枝里

信澤 枝理 ノブサワ エリ

信澤 枝里

Research Projects

Research Products

Co-Researchers

Basic analysis on the mechanism of antigenic change in influenza B viruses using bioinformaticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ファージディスプレイ法によるミミック抗原の作製とインフルエンザワクチンの開発研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of the restriction of amino acid substitution on the hemagglutinin molecule of influenza A virus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

STUDY ON THE MOLECULAR BASIS OF RECEPTOR-RECOGNITION MECHANISM BY RECENT HUMAN INFLEUNZA VIRUSESPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Potential use of recombinant pertussis vaccine for intranasal administration

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

molecular basis for the virion formation of influenza virus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

STUDY ON THE NUEROVIRULENCE OF RECENT HUMAN INFLUENZA VIRUSESPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study on the molecular basis for neurovirulence of influenza virus.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MOLECULAR BASIS OF NOVEL RECEPTOR BINDING SPECIFICITY OF RECENT ISOLATES OF HUMAN INFLUENZA A VIRUSESPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

再構成ウィルス粒子を用いた膜融合機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of the production of human antibody in vitro expression system and recognition of epitope on the HA protein by human immune system.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Analysis of the Structure of Receptor Binding Site of Hemagglutin in Molecule of Influenza A Virus and of the Characteristics of Receptor.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effects of single-point amino acid substitutions on the structure and function neuraminidase proteins in influenza A virus2008

Author(s)

NOBUSAWA Eri 信澤枝里

信澤枝理ノブサワエリ

信澤枝里