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Watanabe Kunihiko  渡部 邦彦

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WATANABE Kunihiko  渡部 邦彦

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Researcher Number 90184001
Other IDs
Affiliation (based on the past Project Information) *help 2020 – 2022: 京都府立大学, 生命環境科学研究科, 教授
2016 – 2017: 京都府立大学, 生命環境科学研究科, 教授
2015: 京都府立大学, 生命環境科学研究科(系), 教授
2004 – 2006: 京都府立大学, 農学研究科, 助教授
2002: Kyoto Prefectural University Department of Applied Biochemistry Associate professor, 農学研究科, 助教授 … More
2001: 京都府立大学, 農学部, 助教授
1998 – 1999: 京都府立大学, 農学部, 助教授
1993 – 1996: 京都府立大学, 農学部, 講師
1989 – 1990: 京都府立大学, 農学部, 助手 Less
Review Section/Research Field
Principal Investigator
応用微生物学・応用生物化学 / Applied microbiology / Basic Section 38020:Applied microbiology-related
Except Principal Investigator
Applied microbiology / 応用微生物学・応用生物化学 / 応用生物化学・栄養化学
Keywords
Principal Investigator
HrcA / シャペロン / プロテアーゼ / 好熱性細菌 / 膜小胞 / FtsZ / DnaK / 好熱菌 / ジスルフィドオキシドレダクターゼ / タンパク質ジスルフィドオキシドリダクターゼ … More / ジスルフィドオキシドレダクターぜ / 産業廃棄物 / トリ羽毛 / プロテインオキシドレダクターぜ / 羽毛分解 / バイオポリマー / タンパク質酸化還元酵素 / トリ羽毛分解 / 温度感受性 / ジスルフィドオキシダーゼ / 表面提示 / 巨大分子複合体 / hard-to-degrade proteins / keratin / thermophilic enzyme / thermophile / protease / peptidase / collagen / 細胞外マトリックス / 難分解性タンパク質 / ペプチダーゼ / ケラチン / 好熱性酵素 / 難分解性動物タンパク質 / コラーゲン / GroEL / thermosensor / CIRCE / 熱センター / DNA結合タンパク質 / 熱ショック / 熱センサー / cell division / DanK / chaperone / フィラメント化 / フィラメント / 細胞分裂 / 不可逆失活 / ペピチジルプロリルイソメラーゼ / ペプチジルプロリルシストランスイソメラーゼ / シャペロニン … More
Except Principal Investigator
Corynebacterium ammoniagenes / Glucose-6-P dehydrogenase / Glucose-6-P isomerase / E.coli / Bacillus subtilis / 部位特異的変異 / Purinenucleoside Production / Purinenucleotide Production / Purinenucleotide Biosynthesis / 好熱性細菌 / Coryne.ammoniagenes / プリンヌクレオシド生産 / プリンヌクレオチド生産 / プリンヌクレオチド生合成 / thermophile / reversibility / differential scanning calorimetry / site-directed mutagenesis / protein engineering / thermostability / proline / 不可逆性 / 好熱菌 / 可逆性 / 示差熱測定 / タンパク質工学 / 耐熱性 / プロリン / 02General principle for increasing protein thermostability / Site-directed mutagenesis / Oligo-1, 6-glucosidase / Proline residues / Thermostable enzyme / Protein engineering / The proline theory / オリゴ-1、6-グルコシダ-ゼ / オリゴー1.6ーグルコシダ-ゼ / オリゴー1,6グルコシダ-ゼ / プロリン残基 / 耐熱性酵素 / 蛋白質工学 / 蛋白質耐熱化の一般則 / プロリン説 Less
  • Research Projects

    (10 results)
  • Research Products

    (30 results)
  • Co-Researchers

    (5 People)
  •  Challenge for degradation of chicken feathers by a thermophilic bacterium Meiothermus ruber H328Principal Investigator

    • Principal Investigator
      Watanabe Kunihiko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38020:Applied microbiology-related
    • Research Institution
      Kyoto Prefectural University
  •  Establishment of novel bacterial functions with macromolecular compelxes of proteases and virus-like membrane vesicles and their applicationPrincipal Investigator

    • Principal Investigator
      Watanabe Kunihiko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied microbiology
    • Research Institution
      Kyoto Prefectural University
  •  Studies on the Mechanism of Purinenucleotide Biosynthesis and Permeability

    • Principal Investigator
      MATSUI Hiroshi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied microbiology
    • Research Institution
      Kyoto Prefectural University
  •  Practical approaches to decomposition of hard-to-degrade proteins by thermoophilic enzymes.Principal Investigator

    • Principal Investigator
      WATANABE Kunihiko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied microbiology
    • Research Institution
      Kyoto Prefectural University
  •  Bacterial thermosensor protein : studies on the functions of HrcA protein as a transcriptional regulator for chaperone genes.Principal Investigator

    • Principal Investigator
      WATANABE Kunihiko
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Kyoto Prefectural University
  •  Studies on the functions of chaperones participating cell morphology and on their relation with cell divisionPrincipal Investigator

    • Principal Investigator
      WATANABE Kunihiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Kyoto Prefectural University
  •  Protein thermostabilization by proline substitutions in accordance with the proline rule

    • Principal Investigator
      SUZUKI Yuzuru
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Kyoto Prefectural University, Department of Agricultural Chemistry
  •  好熱菌シャペロンの有用タンパク質不可逆失活抑制と免疫抑制剤開発への応用Principal Investigator

    • Principal Investigator
      渡部 邦彦
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Kyoto Prefectural University
  •  好熱菌のシャペロン遺伝子単離と有用タンパク質大量発現改善への応用Principal Investigator

    • Principal Investigator
      渡部 邦彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Kyoto Prefectural University
  •  Construction of a General Principle for Increasing Protein ThermostAbility ; Verification of The Proline Theory

    • Principal Investigator
      SUZUKI Yuzuru
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用生物化学・栄養化学
    • Research Institution
      Kyoto Prefectural University

All 2023 2022 2021 2020 2018 2017 2016 2015 2006 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Combination of four bacterial strains isolated from Yamahai-shubo in traditional Japanese sake brewing2023

    • Author(s)
      Hisashi Fujiwara, Kunihiko Watanabe, Yoshinori Wakai
    • Journal Title

      Food Science & Nutrition

      Volume: in press Issue: 6 Pages: 2990-3001

    • DOI

      10.1002/fsn3.3280

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K05789
  • [Journal Article] Changes in the Physical Properties of the Feather Keratin Resin by the Enzymatic Pre-Treatment of the Feathers or the Slight Reinforcement with the Wood Fibers2022

    • Author(s)
      Kawahara Yutaka、Kurihara Natsumi、Ohno Takeki、Watanabe Kunihiko、Tanaka Shun-ichi、Yamamoto Masaki、Wakizaka Hiroyuki
    • Journal Title

      Journal of Fiber Science and Technology

      Volume: 78 Issue: 7 Pages: 114-120

    • DOI

      10.2115/fiberst.2022-0013

    • ISSN
      2189-7654
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K05386, KAKENHI-PROJECT-20K05789
  • [Journal Article] Study of the Ca2+-dependent gene expression of EuPrt, an extracellular metalloprotease produced by the psychro-tolerant bacterium Exiguobacterium undae Su-12022

    • Author(s)
      Kiyoaki Arakawa, Junta Yanai, Kunihiko Watanabe
    • Journal Title

      Bioscience Biotechnology and Biochemistry

      Volume: 86 Issue: 9 Pages: 1308-1317

    • DOI

      10.1093/bbb/zbac109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K05789
  • [Journal Article] Enhancement of membrane vesicle production by disrupting degP gene in Meiothermus ruber H3282021

    • Author(s)
      Yuki Asano, Manato Onishi, Kaito Nishi, Kazunori Kawasak, Kunihiko Watanabe.
    • Journal Title

      AMB Express

      Volume: 11 Issue: 1 Pages: 170-170

    • DOI

      10.1186/s13568-021-01328-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K05789
  • [Journal Article] Molecular characterization of a prolyl endopeptidase from a feather-degrading thermophile Meiothermus ruber H3282020

    • Author(s)
      Fumi Yamamoto, Hironobu Morisaka, Mitsuyoshi Ueda, Kunihiko Watanabe
    • Journal Title

      The Journal of Biochemistry

      Volume: 168 Issue: 5 Pages: 499-508

    • DOI

      10.1093/jb/mvaa069

    • NAID

      40022409815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K05789
  • [Journal Article] Draft genome sequence of Caenibacillus caldisaponilyticus B157T, a thermophilic and phospholipase-producing bacterium isolated from acidulocompost2017

    • Author(s)
      Yoshiyuki Tsujimoto, Ryo Saito, Takehiko Sahara, Nobutada Kimura, Naoki Tsuruoka, Yasushi Shigeri, Kunihiko Watanabe
    • Journal Title

      Genome Announcements

      Volume: 5 Issue: 13

    • DOI

      10.1128/genomea.00089-17

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07366
  • [Journal Article] Keratinase H328 and Keratinase H328-Proteinase K Treatments for Wool Surface2017

    • Author(s)
      Chendi Tu, Fusako Kawai, Kunihiko Watanabe, Kiyomi Okada, Sachiko Sukigara
    • Journal Title

      Journal of Fiber Science and Technology

      Volume: 73 Issue: 6 Pages: 126-134

    • DOI

      10.2115/fiberst.2017-0018

    • NAID

      130005697118

    • ISSN
      2189-7654
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07366
  • [Journal Article] Caenibacillus caldisaponilyticus gen. nov., sp. nov., a thermophilic, spore-forming and phospholipid-degrading bacterium isolated from acidulocompost2016

    • Author(s)
      Yoshiyuki Tsujimoto, Ryo Saito, Hiroto Furuya, Daisuke Ishihara, Takehiko Sahara, Nobutada Kimura, Tokuzo Nishino, Naoki Tsuruoka, Yasushi Shigeri, Kunihiko Watanabe
    • Journal Title

      International Journal of Systematic and Evolutionary Microbiology

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07366
  • [Journal Article] Bacterial membrane vesicles (MVs): Novel tools as nature- and nano-carriers for immunogenic antigen, enzyme support, and drug delivery2016

    • Author(s)
      Kunihiko Watanabe
    • Journal Title

      Applied Microbiology and Biotechnology

      Volume: 100 Issue: 23 Pages: 9837-9843

    • DOI

      10.1007/s00253-016-7916-7

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K07366
  • [Journal Article] 細菌が放出する膜小胞(membrane vesicle)の機能と生合成機構そして応用に向けた研究動向2016

    • Author(s)
      渡部 邦彦
    • Journal Title

      化学と生物

      Volume: 54 Pages: 720-725

    • NAID

      130006083309

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07366
  • [Journal Article] 細菌が出芽する?いえいえ,放出されるのは膜小胞2015

    • Author(s)
      渡部 邦彦
    • Journal Title

      日本生物工学会誌

      Volume: 93 Pages: 412-412

    • Open Access
    • Data Source
      KAKENHI-PROJECT-15K07366
  • [Journal Article] Green polymers from Geobacillus thermodenitr f cans DSM465- candidates for molecularly imprinted materials.2006

    • Author(s)
      Masakazu Yoshikawa, Kensuke Kawamura, Akinori Ejima, Takashi Aoki, Shinichi Sakurai, Kyoko Hayashi, Kunihiko Watanabe.
    • Journal Title

      Macromolecular Bioscience 6

      Pages: 210-215

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16580062
  • [Journal Article] Decomposition of hard-to-degrade extracellular-matrix proteins by thermophilic bacteria.2006

    • Author(s)
      Suzuki, Y., Tsujimoto, Y., Matsui, H., Watanabe, K.
    • Journal Title

      J.Biosci.Bioeng. (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16580062
  • [Journal Article] Two thimet oligopeptidase-like Pz peptidases produced by a collagen-degrading thermophile Geobacillus collagenovorans MO-1.2005

    • Author(s)
      Ryoma Miyake, Yasushi Shigeri, Yoshiro Tatsu, Noboru Yumoto, Midori Umekawa, Yoshiyuki Tsujimoto, Hiroshi Matsui, Kunihiko Watanabe.
    • Journal Title

      Journal of Bacteriology 187

      Pages: 4140-4148

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16580062
  • [Journal Article] An Aneurinibacillus sp.strain AM-1 produces a proline-specific aminopeptidase useful for collagen degradation.2004

    • Author(s)
      A.Murai, Y.Tsujimoto, H.Matsui, K.Watanabe.
    • Journal Title

      Journal of Applied Microbiology 96

      Pages: 810-818

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16580062
  • [Journal Article] Collagenolytic proteases from bacteria.2004

    • Author(s)
      K.Watanabe
    • Journal Title

      Applied Microbiology and Biotechnology 63

      Pages: 520-526

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16580062
  • [Journal Article] Thermostable natural protein polymers from Geobacillus thermodenitrificans DSM465 as membrane materials for vapor permeation.2004

    • Author(s)
      Masakazu Yoshikawa, Kensuke Kawamura, Akinori Ejima, Takashi Aoki, Kunihiko Watanabe, Michael D.Guiver, Gilles P.Robertson.
    • Journal Title

      Journal of Membrane 26

      Pages: 384-387

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16580062
  • [Journal Article] An Aneurinibacillus sp. strain AM-1 produces a proline-specific aminopeptidase useful for collagen degradation.2004

    • Author(s)
      A.Murai, Y.Tsujimoto, H.Matsui, K.Watanabe
    • Journal Title

      Journal of Applied Microbiology 96

      Pages: 810-818

    • Data Source
      KAKENHI-PROJECT-16580062
  • [Journal Article] An Aneurinibacillus sp.strain AM-1 produces a proline-specific aminopeptidase useful for collagen degradation2004

    • Author(s)
      A.Murai, Y.Tsujimoto, H.Matsui, K.Watanabe.
    • Journal Title

      Journal of Applied Microbiology 96

      Pages: 810-818

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16580062
  • [Journal Article] Decomposition of hard-to-degrade extracellular-matrix proteins by thermophilic bacteria.

    • Author(s)
      Yasunori Suzuki, Yoshiyuki Tsujimoto, Hiroshi Matsui, Kunihiko Watanabe.
    • Journal Title

      Journal of Bioscience and Bioengineering (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16580062
  • [Presentation] 好熱性細菌Meiothermus ruber H328 株におけるケラ チン分解性プロテアーゼ(MrH_0874)のリクルート解析2022

    • Author(s)
      高岡 菜都美、渡部 邦彦
    • Organizer
      日本農芸化学会
    • Data Source
      KAKENHI-PROJECT-20K05789
  • [Presentation] 膜小胞応用のための量的コントロールおよび表面提示・改良に関する研究2021

    • Author(s)
      渡部邦彦
    • Organizer
      日本農芸化学会 2021年大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K05789
  • [Presentation] Enhancement of Membrane Vesicle Production by Disrupting the degP Gene in Meiothermus ruber H3282021

    • Author(s)
      Kunihiko Watanabe
    • Organizer
      EMBO WS Bacterial Membrane Vesicles
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K05789
  • [Presentation] degP 遺伝子破壊によるMeiothermus ruber H328 株 の膜小胞産生能強化に関する研究2020

    • Author(s)
      淺野優希,大西愛航,川崎一則,渡部邦彦
    • Organizer
      日本農芸化学会 2020年大会 福岡大会
    • Data Source
      KAKENHI-PROJECT-20K05789
  • [Presentation] 膜小胞の量的コントロールに関する研究-シャペロン遺伝子破壊による膜小胞産生能向上の検討2020

    • Author(s)
      渡部邦彦
    • Organizer
      日本農芸化学会 2020年大会 福岡大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K05789
  • [Presentation] 細菌が放出する膜小胞に関する研究 -シャペロン遺伝子破壊による 膜小胞産生能向上の検討-2020

    • Author(s)
      渡部邦彦
    • Organizer
      日本農芸化学会 関西支部 web講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K05789
  • [Presentation] Meiothermus ruber H328株由来 protein disulfide oxidoreductase (PDO) 発現量増強株の 羽毛分解への影響2018

    • Author(s)
      武田梨花、西海斗、渡部邦彦
    • Organizer
      日本農芸化学会 2018年大会
    • Data Source
      KAKENHI-PROJECT-15K07366
  • [Presentation] 好熱性細菌 Meiothermus ruber H328 株の degP 遺伝子破壊株を用いた膜小胞産生に関する研究2017

    • Author(s)
      渡部邦彦,大西愛航,清水 歩,西 海斗,川崎一則
    • Organizer
      日本農芸化学会2017年大会
    • Place of Presentation
      京都女子大学(京都府、京都市)
    • Year and Date
      2017-03-18
    • Data Source
      KAKENHI-PROJECT-15K07366
  • [Presentation] 細菌の高次機能開拓:細菌が産生する膜小胞の可能性~トリ羽毛分解から出発して2017

    • Author(s)
      渡部邦彦
    • Organizer
      平成28年度3研究会(発酵と代謝、アルコール・バイオマス、新資源生物変換)合同講演会
    • Place of Presentation
      東京大学中島董一郎記念ホール(東京都、文京区)
    • Year and Date
      2017-03-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K07366
  • [Presentation] 膜小胞を産生するMeiothermus ruberH328株によるトリ羽毛分解に関する研究 ~ケラチン分解性プロテアーゼ遺伝子破壊株の作成とトリ羽毛分解の検討~2016

    • Author(s)
      清水 歩、西 海斗、俣野 明日香、森川 拓磨、増村 威宏、佐生 愛、川崎 一則、茂里 康、渡部 邦彦
    • Organizer
      日本農芸化学会2016年大会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-15K07366
  • 1.  SUZUKI Yuzuru (50046471)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  増村 威宏 (50254321)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  MATSUI Hiroshi (40336730)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  TSUJIMOTO Yoshiyuki (20315930)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  川崎 一則 (40356837)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results

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