WATANABE Kunihiko 渡部邦彦

Researcher Number	90184001
Affiliation *help	2016 – 2018 : 京都府立大学, 生命環境科学研究科, 教授 2015 : 京都府立大学, 生命環境科学研究科(系), 教授 2004 – 2006 : 京都府立大学, 農学研究科, 助教授 2002 : Kyoto Prefectural University Department of Applied Biochemistry Associate professor, 農学研究科, 助教授 2001 : 京都府立大学, 農学部, 助教授 … More
Review Section/Research Field	Principal Investigator 応用微生物学・応用生物化学 / Applied microbiology Except Principal Investigator Applied microbiology / 応用微生物学・応用生物化学 / 応用生物化学・栄養化学
Keywords	Principal Investigator シャペロン / HrcA / DnaK / プロテアーゼ / FtsZ / 好熱性細菌 / 好熱菌 / フィラメント化 / 細胞分裂 / protease … More Except Principal Investigator Glucose-6-P dehydrogenase / E.coli / 部位特異的変異 / Corynebacterium ammoniagenes / Bacillus subtilis / Glucose-6-P isomerase / オリゴー1.6ーグルコシダ-ゼ / Purinenucleotide Production / thermostability / オリゴ-1、6-グルコシダ-ゼ / reversibility / プリンヌクレオシド生産 / The proline theory / 好熱性細菌 / Coryne.ammoniagenes / Oligo-1, 6-glucosidase / Protein engineering / プロリン説 / thermophile / プリンヌクレオチド生合成 / Thermostable enzyme / proline / プロリン / Purinenucleotide Biosynthesis / protein engineering / プリンヌクレオチド生産 / 可逆性 / Site-directed mutagenesis / differential scanning calorimetry / オリゴー1,6グルコシダ-ゼ / 02General principle for increasing protein thermostability / 好熱菌 / 示差熱測定 / 耐熱性 / site-directed mutagenesis / Purinenucleoside Production / 耐熱性酵素 / プロリン残基 / 蛋白質工学 / 不可逆性 / 蛋白質耐熱化の一般則 / タンパク質工学 / Proline residues Less

プロテアーゼ巨大分子複合体とウイルス様膜小胞による細菌の新規細胞機能の確立と応用Principal InvestigatorOngoing
- Principal Investigator
  
  渡部邦彦
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied microbiology
- Research Institution
  Kyoto Prefectural University
Studies on the Mechanism of Purinenucleotide Biosynthesis and Permeability
- Principal Investigator
  
  MATSUI Hiroshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied microbiology
- Research Institution
  Kyoto Prefectural University
Practical approaches to decomposition of hard-to-degrade proteins by thermoophilic enzymes.Principal Investigator
- Principal Investigator
  
  WATANABE Kunihiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied microbiology
- Research Institution
  Kyoto Prefectural University
Bacterial thermosensor protein : studies on the functions of HrcA protein as a transcriptional regulator for chaperone genes.Principal Investigator
- Principal Investigator
  
  WATANABE Kunihiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto Prefectural University
Studies on the functions of chaperones participating cell morphology and on their relation with cell divisionPrincipal Investigator
- Principal Investigator
  
  WATANABE Kunihiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto Prefectural University
Protein thermostabilization by proline substitutions in accordance with the proline rule
- Principal Investigator
  
  SUZUKI Yuzuru
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto Prefectural University, Department of Agricultural Chemistry
好熱菌シャペロンの有用タンパク質不可逆失活抑制と免疫抑制剤開発への応用Principal Investigator
- Principal Investigator
  
  渡部邦彦
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto Prefectural University
好熱菌のシャペロン遺伝子単離と有用タンパク質大量発現改善への応用Principal Investigator
- Principal Investigator
  
  渡部邦彦
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto Prefectural University
Construction of a General Principle for Increasing Protein ThermostAbility ; Verification of The Proline Theory
- Principal Investigator
  
  SUZUKI Yuzuru
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Kyoto Prefectural University

All 2017 2016 2015 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] Draft genome sequence of Caenibacillus caldisaponilyticus B157T, a thermophilic and phospholipase-producing bacterium isolated from acidulocompost2017
- Author(s)
  Yoshiyuki Tsujimoto, Ryo Saito, Takehiko Sahara, Nobutada Kimura, Naoki Tsuruoka, Yasushi Shigeri, Kunihiko Watanabe
- Journal Title
  
  Genome Announcements
  
  Volume : 5
- DOI
  10.1128/genomeA.00089-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07366
[Journal Article] 細菌が放出する膜小胞（membrane vesicle）の機能と生合成機構そして応用に向けた研究動向2016
- Author(s)
  渡部　邦彦
- Journal Title
  
  化学と生物
  
  Volume : 54 Pages : 720-725
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07366
[Journal Article] Bacterial membrane vesicles (MVs): Novel tools as nature- and nano-carriers for immunogenic antigen, enzyme support, and drug delivery2016
- Author(s)
  Kunihiko Watanabe
- Journal Title
  
  Applied Microbiology and Biotechnology
  
  Volume : 100 Pages : 9837-9843
- DOI
  10.1007/s00253-016-7916-7
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07366
[Journal Article] 細菌が放出する膜小胞（membrane vesicle）の機能と生合成機構そして応用に向けた研究動向2016
- Author(s)
  渡部　邦彦
- Journal Title
  
  化学と生物
  
  Volume : 印刷中
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07366
[Journal Article] Caenibacillus caldisaponilyticus gen. nov., sp. nov., a thermophilic, spore-forming and phospholipid-degrading bacterium isolated from acidulocompost2016
- Author(s)
  Yoshiyuki Tsujimoto, Ryo Saito, Hiroto Furuya, Daisuke Ishihara, Takehiko Sahara, Nobutada Kimura, Tokuzo Nishino, Naoki Tsuruoka, Yasushi Shigeri, Kunihiko Watanabe
- Journal Title
  
  International Journal of Systematic and Evolutionary Microbiology
  
  Volume : in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07366
[Journal Article] 細菌が出芽する？いえいえ，放出されるのは膜小胞2015
- Author(s)
  渡部　邦彦
- Journal Title
  
  日本生物工学会誌
  
  Volume : 93 Pages : 412-412
- Open Access
- Data Source
  KAKENHI-PROJECT-15K07366
[Journal Article] Green polymers from Geobacillus thermodenitr f cans DSM465- candidates for molecularly imprinted materials.2006
- Author(s)
  Masakazu Yoshikawa, Kensuke Kawamura, Akinori Ejima, Takashi Aoki, Shinichi Sakurai, Kyoko Hayashi, Kunihiko Watanabe.
- Journal Title
  
  Macromolecular Bioscience 6
  
  Pages : 210-215
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580062
[Journal Article] Decomposition of hard-to-degrade extracellular-matrix proteins by thermophilic bacteria.2006
- Author(s)
  Suzuki, Y., Tsujimoto, Y., Matsui, H., Watanabe, K.
- Journal Title
  
  J.Biosci.Bioeng. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580062
[Journal Article] Two thimet oligopeptidase-like Pz peptidases produced by a collagen-degrading thermophile Geobacillus collagenovorans MO-1.2005
- Author(s)
  Ryoma Miyake, Yasushi Shigeri, Yoshiro Tatsu, Noboru Yumoto, Midori Umekawa, Yoshiyuki Tsujimoto, Hiroshi Matsui, Kunihiko Watanabe.
- Journal Title
  
  Journal of Bacteriology 187
  
  Pages : 4140-4148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580062
[Journal Article] An Aneurinibacillus sp.strain AM-1 produces a proline-specific aminopeptidase useful for collagen degradation2004
- Author(s)
  A.Murai, Y.Tsujimoto, H.Matsui, K.Watanabe.
- Journal Title
  
  Journal of Applied Microbiology 96
  
  Pages : 810-818
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580062
[Journal Article] Collagenolytic proteases from bacteria.2004
- Author(s)
  K.Watanabe
- Journal Title
  
  Applied Microbiology and Biotechnology 63
  
  Pages : 520-526
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580062
[Journal Article] An Aneurinibacillus sp.strain AM-1 produces a proline-specific aminopeptidase useful for collagen degradation.2004
- Author(s)
  A.Murai, Y.Tsujimoto, H.Matsui, K.Watanabe.
- Journal Title
  
  Journal of Applied Microbiology 96
  
  Pages : 810-818
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580062
[Journal Article] An Aneurinibacillus sp. strain AM-1 produces a proline-specific aminopeptidase useful for collagen degradation.2004
- Author(s)
  A.Murai, Y.Tsujimoto, H.Matsui, K.Watanabe
- Journal Title
  
  Journal of Applied Microbiology 96
  
  Pages : 810-818
- Data Source
  KAKENHI-PROJECT-16580062
[Journal Article] Thermostable natural protein polymers from Geobacillus thermodenitrificans DSM465 as membrane materials for vapor permeation.2004
- Author(s)
  Masakazu Yoshikawa, Kensuke Kawamura, Akinori Ejima, Takashi Aoki, Kunihiko Watanabe, Michael D.Guiver, Gilles P.Robertson.
- Journal Title
  
  Journal of Membrane 26
  
  Pages : 384-387
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580062
[Journal Article] Decomposition of hard-to-degrade extracellular-matrix proteins by thermophilic bacteria.
- Author(s)
  Yasunori Suzuki, Yoshiyuki Tsujimoto, Hiroshi Matsui, Kunihiko Watanabe.
- Journal Title
  
  Journal of Bioscience and Bioengineering (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580062
[Presentation] 好熱性細菌 Meiothermus ruber H328 株の degP 遺伝子破壊株を用いた膜小胞産生に関する研究2017
- Author(s)
  渡部邦彦，大西愛航，清水　歩，西　海斗，川崎一則
- Organizer
  日本農芸化学会2017年大会
- Place of Presentation
  京都女子大学（京都府、京都市）
- Year and Date
  2017-03-18
- Data Source
  KAKENHI-PROJECT-15K07366
[Presentation] 細菌の高次機能開拓：細菌が産生する膜小胞の可能性～トリ羽毛分解から出発して2017
- Author(s)
  渡部邦彦
- Organizer
  平成28年度３研究会（発酵と代謝、アルコール・バイオマス、新資源生物変換）合同講演会
- Place of Presentation
  東京大学中島董一郎記念ホール（東京都、文京区）
- Year and Date
  2017-03-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K07366
[Presentation] 膜小胞を産生するMeiothermus ruberH328株によるトリ羽毛分解に関する研究～ケラチン分解性プロテアーゼ遺伝子破壊株の作成とトリ羽毛分解の検討～2016
- Author(s)
  清水歩、西海斗、俣野明日香、森川拓磨、増村威宏、佐生愛、川崎一則、茂里康、渡部邦彦
- Organizer
  日本農芸化学会2016年大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K07366

1. SUZUKI Yuzuru (50046471)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
2. MATSUI Hiroshi (40336730)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
3. TSUJIMOTO Yoshiyuki (20315930)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
4. 川崎一則 (40356837)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
5. 増村威宏 (50254321)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results

WATANABE Kunihiko 渡部 邦彦

Research Projects

Research Products

Co-Researchers

プロテアーゼ巨大分子複合体とウイルス様膜小胞による細菌の新規細胞機能の確立と応用Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the Mechanism of Purinenucleotide Biosynthesis and Permeability

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Practical approaches to decomposition of hard-to-degrade proteins by thermoophilic enzymes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Bacterial thermosensor protein : studies on the functions of HrcA protein as a transcriptional regulator for chaperone genes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the functions of chaperones participating cell morphology and on their relation with cell divisionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Protein thermostabilization by proline substitutions in accordance with the proline rule

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

好熱菌シャペロンの有用タンパク質不可逆失活抑制と免疫抑制剤開発への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

好熱菌のシャペロン遺伝子単離と有用タンパク質大量発現改善への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of a General Principle for Increasing Protein ThermostAbility ; Verification of The Proline Theory

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Draft genome sequence of Caenibacillus caldisaponilyticus B157T, a thermophilic and phospholipase-producing bacterium isolated from acidulocompost2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 細菌が放出する膜小胞（membrane vesicle）の機能と生合成機構そして応用に向けた研究動向2016

Author(s)

Journal Title

Data Source

[Journal Article] Bacterial membrane vesicles (MVs): Novel tools as nature- and nano-carriers for immunogenic antigen, enzyme support, and drug delivery2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 細菌が放出する膜小胞（membrane vesicle）の機能と生合成機構そして応用に向けた研究動向2016

Author(s)

Journal Title

Data Source

[Journal Article] Caenibacillus caldisaponilyticus gen. nov., sp. nov., a thermophilic, spore-forming and phospholipid-degrading bacterium isolated from acidulocompost2016

Author(s)

Journal Title

Data Source

WATANABE Kunihiko 渡部邦彦

[Presentation] 膜小胞を産生するMeiothermus ruberH328株によるトリ羽毛分解に関する研究～ケラチン分解性プロテアーゼ遺伝子破壊株の作成とトリ羽毛分解の検討～2016