Ueda Tadashi 植田正

… Alternative Names

Researcher Number	90184928
Other IDs
Affiliation (Current)	2022: 九州大学, 薬学研究院, 教授
Affiliation (based on the past Project Information) *help	2016 – 2019: 九州大学, 薬学研究院, 教授 2011 – 2016: 九州大学, 薬学研究科(研究院), 教授 2015: 九州大学, 大学院薬学研究院, 教授 2010 – 2012: 九州大学, 大学院・薬学研究院, 教授 2008 – 2012: Kyushu University, 薬学研究院, 教授 … More
Review Section/Research Field	Principal Investigator Biological pharmacy / Laboratory medicine / Physical pharmacy / Biological Sciences / Pain science / Chemistry related to living body / Biophysics / Structural biochemistry / Applied pharmacology / Medium-sized Section 47:Pharmaceutical sciences and related fields … More Except Principal Investigator … More
Keywords	Principal Investigator NMR / リゾチーム / Fab / 安定化 / 蛋白質工学 / 蛋白質 / 巻き戻し / アミノ酸改変 / 抗体 / 神経障害性疼痛 … More Except Principal Investigator ATP / リゾチーム / フォルディング / DnaA / タンパク質 / DNA複製 / 細胞周期 / 大腸菌 / ランダムライブラリー / タンパク質の高次構造 / ペプチド / タンパク質複合体 / タンパク質機能構造解析 / 分析化学 / アミノ酸 / 光学分割 / Porphyromonas gingivalis / phage-displayed peptide library / DnaAタンパク質 / DNAポリメラーゼ / 抗菌剤 / DNA replication / Cell cycle / DNA polymerase / 抗イディオタイプ抗体 / リコンビナント単鎖Fv抗体 / エピトープ / II型コラーゲン / ホモロジーモデリング / 核磁気共鳴(NMR) / タンパク質の結晶化 / 変異タンパク質 / 構造形成機構 / 再生反応 / 巻き戻し / カルシウム結合部位 / アグリケーション / ラクトアルブミン / bota-amilaid / microglio / Alzheimer / inflammation / cytokine / free radical / ジ置換アミノ酸 / コンフォメーション / 2次構造 / アミロイド凝集体 / ヘリックス / シート構造 / DNA 複製開始 / DnaA, 細胞周期 / 蛋白質複合体 / 蛋白質機能構造解析 / ヘリカーゼ / DNA動態変化 / DnaB / oriC / 細胞周期制御 / 染色体複製開始制御 / タンパク質高次複合体 / 試験管内再構成 / 複製開始複合体 / へリカーゼ装着 / 複製開始の制御機構 / 非コードDNA / 核酸タンパク質複合体 / メタボローム / メタボロミクス / 遺伝子工学 / ニワトリリゾチ-ム / N末端プロセッシング / デアミデ-ション / 巻戻し / SS-SH交換反応 / 変異リゾチ-ム / Gene engineering / Chicken lysozyme / Eschericia coli / Processing of N-terminal methionine / Deaminated / Renaturation / 不可逆化学反応 / 添加剤 / スクロース / トレハロース / トリフルオロエタノール / 不可逆失活抑制 / Asn-Gly配列 / Asp-Gly配列 / IRREVERSIBLE CHMEICAL REACTION / ADDITIVE / PROTEIN / PEPTIDE / SUCROSE / TREHALOSE / 線毛 / モノクローナル抗体 / B細胞エピトープ / 歯周病 / Immunodominance / 立体構造 / 変性 / 未変性 / fimbriae / monoclonal antibodies / B cell epitopes / higher order structure of proteins / periodontal diseases / AAA^+ファミリー / DNA結合 / NMR / X線結晶解析 / AAA+ファミリー / 染色体複製制御 / DnaA protein / E.coli / AAAt motif / Antibiotics / プロテオミクス / タンパク質構造解析 / タンパク質機能解析 / タンパク質相互作用 / Protein complex / Protein function / Proteomix Less

Fundamental study on depression of Anti-Drug Antibodies by use of immune tolerancePrincipal Investigator
- Principal Investigator
  
  Tadashi Ueda
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kyushu University
Fundamental Study on Preparations for Therapeutic Antibodies with Less Productions of Anti-Drug AntibodiesPrincipal Investigator
- Principal Investigator
  
  Ueda Tadashi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyushu University
Establishment of research foundation on "objective pain assessment" using animal models suffering from neuropathic painPrincipal Investigator
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyushu University
Early diagnosis of the defect in amino acid metabolism using chiral amino acid metabolomics
- Principal Investigator
  
  Kenji Hamase
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyushu University
Study on the development of molecules for depressing neuropathic pain based on tertiary structure of human P2X4 receptorPrincipal Investigator
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pain science
- Research Institution
  Kyushu University
Development of Fab molecule with the stable scaffold for next generationPrincipal Investigator
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyushu University
Molecular analyses on the replication initiation complex and its novel regulatory factors in E. coli
- Principal Investigator
  
  KATAYAMA Tsutomu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Kyushu University
Development of an enantioselective amino acid metabolome analysismethod and its clinical applications
- Principal Investigator
  
  HAMASE Kenji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyushu University
Improved function of ketoamine oxidase for clinical examination reagent of diabetes by use of multiple approachesPrincipal Investigator
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyushu University
High-order Structure-based Molecular Mechanisms in Replicational Initiation Complex Formation, DNA Unwinding, and Dissociation
- Principal Investigator
  
  KATAYAMA Tsutomu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Kyushu University
アミロイド線維の凝集が関与するフォールディング病への有機化学からのアプローチ
- Principal Investigator
  
  田中正一
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyushu University
βアミロイド立体構造のミクログリア活性化への影響とその抑制についての研究
- Principal Investigator
  
  門司晃
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Protein Dynamics in Complex Apparatus for the Initiation and Regulation of the Chromosomal Replication
- Principal Investigator
  
  KATAYAMA Tsutomu
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  KYUSHU UNIVERCITY
核磁気共鳴装置を用いたβアミロイドペプチドのリン酸イオンによる凝集抑制機構の解明Principal Investigator
- Principal Investigator
  
  植田正
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Analysis on mechanism of severe allergic reaction caused by SNP in interleukin 13 using NMRPrincipal Investigator
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  KYUSHU UNIVERSITY
STUDY ON RATIONAL DEVELOPMENT OF NOVEL ANTIBIOTICS TAGRETING DnaA DOMAIN IV
- Principal Investigator
  
  KATAYAMA Tsutomu
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Kyushu University
AnaIysis of dynamic behavior of ribonuclease upon ligand binding using high resolution NMRPrincipal Investigator
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyushu University
カルシウム結合部位を導入したニワトリリゾチーム変異体を用いた再生初期構造の形成要因の解明
- Principal Investigator
  
  井本泰治
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
変異体を用いたリゾチームの構造構築過程の解析
- Principal Investigator
  
  井本泰治
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Analysis of epitope specificity of immune response involved in periodontitis
- Principal Investigator
  
  ITO Hiro-O
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Kagoshima University
  Kyushu University
ランダム変異を用いたリゾチームのフォルディング情報の解析
- Principal Investigator
  
  井本泰治
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
タンパク質の高次構造に依存する抗原エピトープ同定法の開発
- Principal Investigator
  
  ITO Hiro-O
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Kyushu University
STRATEGY FOR DEPRESSION OF IRREVERSIBLE REACTIONS OF PEPTIDES OR PROTEINS AS MEDICINE
- Principal Investigator
  
  IMOTO Taiji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  KYUSHU UNIVERSITY
Construction of an effective renaturation method of denatured proteins based on a biological functionPrincipal Investigator
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyushu University
ランダム変異を用いたリゾチームのフォルディング情報の解析
- Principal Investigator
  
  IMOTO Taiji
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Analysis of dynamic behavior of mutant hen lysozyme with larger catalytic constant using high resolution NMRPrincipal Investigator
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Kyushu University
ペプチドフラグメントを用いたリゾチーム構造形成初期過程の解析Principal Investigator
- Principal Investigator
  
  植田正
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyushu University
カルシウム結合部位を導入した変異リゾチームの巻戻し活性中間体の捕捉とその構造決定Principal Investigator
- Principal Investigator
  
  植田正
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyushu University
Study on the Renaturation of Mutant Lysozymes Expressed in Schericia Coli.
- Principal Investigator
  
  YAMADA Hidenori
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyushu University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] A method to induce hen egg lysozyme-specific humoral immune tolerance in mice by pre-exposition with the protein's oligomers.2019
- Author(s)
  Ohkuri T, Yuge N, Sato K, Ueda T.
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 14 Pages: 100679-100679
- DOI
  10.1016/j.bbrep.2019.100679
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08922, KAKENHI-PROJECT-18K19406
[Journal Article] Relationship between the magnitude of IgE production in mice and conformational stability of the house dust mite allergen, Der p 22016
- Author(s)
  Hitomi Nakamura, Takatoshi Ohkuri, Takanori So, Tadashi Ueda
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 未定 Pages: 2279-2284
- DOI
  10.1016/j.bbagen.2016.04.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15184, KAKENHI-PROJECT-15H04640
[Journal Article] Establishment of a Two-Dimensional HPLC-MS/MS Method Combined with DCl/D<sub>2</sub>O Hydrolysis for the Determination of Trace Amounts of D-Amino Acid Residues in Proteins2015
- Author(s)
  Shoto ISHIGO, Eiichi NEGISHI, Yurika MIYOSHI, Hirohisa ONIGAHARA, Masashi MITA, Tetsuya MIYAMOTO, Haruhiko MASAKI, Hiroshi HOMMA, Tadashi UEDA, Kenji HAMASE
- Journal Title
  
  CHROMATOGRAPHY
  
  Volume: 36 Issue: 2 Pages: 45-50
- DOI
  10.15583/jpchrom.2015.017
- NAID
  130005098795
- ISSN
  1342-8284, 1348-3315
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-25108006, KAKENHI-PROJECT-25293007
[Journal Article] Solution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding2015
- Author(s)
  Igawa T, Abe Y, Tsuda M, Inoue K, Ueda T
- Journal Title
  
  FEBS Lett
  
  Volume: 589(6) Pages: 680-686
- DOI
  10.1016/j.febslet.2015.01.034
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J03712, KAKENHI-PROJECT-26293129, KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-23229008
[Journal Article] Preparation and charac- terization of a monoclonal antibody against the refolded and functional extracellular domain of rat P2X4 receptor2013
- Author(s)
  Igawa, T., Higashi, S., Abe, Y., Ohkuri, T., Tanaka, H., Morimoto, S., Yamashita, T., Tsuda, M., Inoue K., Ueda, T.
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 153(3) Pages: 275-282
- DOI
  10.1093/jb/mvs143
- NAID
  40019589631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-23390155, KAKENHI-PROJECT-23570140
[Journal Article] The DnaA N-terminal domain interacts with Hda to facilitate replicase clamp-madiated inactivation of DnaA2013
- Author(s)
  Su'etsugu, M., Harada, Y., Keyamura, K., Matsunaga, C., Kasho, K., Abe, Y., Ueda, T. and Katayama, T.
- Journal Title
  
  Environ. Microbiol.
  
  Volume: (印刷中) Pages: 3183-3195
- DOI
  10.1111/1462-2920.12147
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370064, KAKENHI-PROJECT-23570140, KAKENHI-PUBLICLY-24119513, KAKENHI-PROJECT-24570010
[Journal Article] Simultaneous two-dimensional HPLC determination of free d-serine and d-alanine in the brain and periphery of mutant rats lacking d-amino-acid oxidase2011
- Author(s)
  Yurika MIYOSHI, et al
- Journal Title
  
  J Chromatogr B Analyt Technol Biomed Life Sci.
  
  Volume: 879 Pages: 3184-3189
- DOI
  10.1016/j.jchromb.2010.08.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J07562, KAKENHI-PROJECT-22390007, KAKENHI-PROJECT-23500508
[Journal Article] A protein's conformational stability is an immunologically dominant factor : Evidence that free-energy barriers for protein unfolding limit the immunogenicity of foreign proteins.2010
- Author(s)
  Okuri T, Nagatomo S, Oda K, So T, Imoto T, Ueda T
- Journal Title
  
  Journal of Immunology
  
  Volume: 185 Pages: 4199-4205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590579
[Journal Article] Effect of His mutants on the fibrillation of amyloidogenic Vλ6 protein under acidic and physiological conditions2010
- Author(s)
  Mishima, Ueda, et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 391
  
  Pages: 615-620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590579
[Journal Article] Residual Structures in Acid-Unfolded States of Vλ6 Proteins Affect Amyloid Fibrillation2009
- Author(s)
  Mishima, Ueda, et al.
- Journal Title
  
  Journal of Molecular Biology 392
  
  Pages: 1033-1043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590579
[Journal Article] Crystal structure of K33 mutant hen lysozymes with enhanced activities.2008
- Author(s)
  Goto T., Ohkuri T., Shioi S., Abe, Y., Imoto T., Ueda.
- Journal Title
  
  The Journal of Biochemistry 144
  
  Pages: 619-623
- NAID
  10024913411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590579
[Journal Article] (*Co-corresponding authors) ; Structure and function of DnaA N-terminal domains : Specific sites and mechanisms in inter-DnaA interaction and in DnaB helicase loading on oriC2007
- Author(s)
  Abe, Y., Jo, T., Matsuda, Y., Matsunaga, C., Katayama, T.*, and Ueda, T.*
- Journal Title
  
  J. Biol. Chem. 282(24)
  
  Pages: 17816-17827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370077
[Journal Article] Assignment of ^1H, ^<13>C and ^<15>N resonances of N-terminal domains of DnaA protein Biomol2007
- Author(s)
  Abe, Y., Watanabe, N., Yoshida, Y., Ebata, F., Katayama, T., and Ueda, T.
- Journal Title
  
  NMR Assign. 1
  
  Pages: 57-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370077
[Presentation] ニワトリリゾチーム多量体前投与による免疫寛容誘導に関する考察2020
- Author(s)
  小山浩舗、大栗誉敏、弓削奈津子、植田　正
- Organizer
  第７回生命分子科学研究会（亀岡市）（新型コロナウイルス感染拡大により延期）
- Data Source
  KAKENHI-PROJECT-18K19406
[Presentation] 酵母Pichia pastorisを用いたヒトCH2ドメインの大量発現系の確立2018
- Author(s)
  小山浩舗、大栗誉敏、阿部義人、植田正
- Organizer
  第35回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-18K19406
[Presentation] 抗ラットP2X4受容体抗体の抗原抗体反応の特徴付け2017
- Author(s)
  岸川秀平, 阿部義人, 井川達弘, 齊藤秀俊, 山下智大, 津田誠, 井上和秀, 植田正
- Organizer
  第17回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-26293129
[Presentation] 抗ラットP2X4 受容体ヘッドドメイン抗体を用いた痛みのイメージングに関する研究2016
- Author(s)
  岸川秀平, 阿部義人, 井川達弘, 齊藤秀俊, 山下智大, 津田誠, 井上和秀, 植田正
- Organizer
  第33回日本薬学会九州支部大会
- Place of Presentation
  鹿児島大学郡元キャンパス
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-26293129
[Presentation] P2X4 受容体細胞外ドメイン認識抗体のスクリーニング系の確立2014
- Author(s)
  永井咲妃, 白石充典, 井川達弘, 斎藤秀俊, 山下智大, 津田誠, 井上和秀, 阿部義人, 植田正
- Organizer
  平成26年度日本生化学会九州支部会
- Place of Presentation
  九州大学コラボステーション I(福岡市)
- Year and Date
  2014-05-18
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] P2X4受容体細胞外ドメイン認識抗体のスクリーニング系の確立2014
- Author(s)
  永井咲妃、白石充典、井川達弘、斎藤秀俊、山下智大、津田誠、井上和秀、阿部義人、植田正
- Organizer
  日本生化学会九州支部会
- Place of Presentation
  九州大学コラボステーションI
- Year and Date
  2014-05-18
- Data Source
  KAKENHI-PROJECT-26293129
[Presentation] P2X4受容体細胞外ドメイン認識抗体の蛍光ゲルろ過法によるスクリーニング系の確立2014
- Author(s)
  永井咲妃、白石充典、井川達弘、斎藤秀俊、山下智大、津田誠、井上和秀、阿部義人、植田正
- Organizer
  第25回クロマトグラフィー会議（京都）
- Place of Presentation
  京都大学（桂キャンパス）船井哲良記念講堂
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-26293129
[Presentation] P2X4受容体細胞外ドメイン認識抗体のスクリーニング系の確立2014
- Author(s)
  永井咲妃, 白石充典, 井川達弘, 斎藤秀俊, 山下智大, 津田誠, 井上和秀, 阿部義人, 植田正
- Organizer
  平成26年度日本生化学会九州支部会
- Place of Presentation
  九州大学病院地区コラボステーションI（福岡市）
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] バイオベター医薬品の創製を目指したプロテインエンジニアリング2013
- Author(s)
  植田　正
- Organizer
  第86回日本生化学会大会（シンポジウムオーガナイザー）
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] NMR を用いたラットP2X4 受容体ヘッドドメインと金属イオンとの相互作用解析2013
- Author(s)
  井川達弘, 阿部義人, 白石充典, 津田誠, 井上和秀, 植田正
- Organizer
  第13回日本蛋白質科学会
- Place of Presentation
  とりぎん会館(鳥取市)
- Year and Date
  2013-06-12
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] バイオベター医薬品の創製を目指したプロテインエンジニアリング2013
- Author(s)
  植田正
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2013-09-11
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] バイオベターな医薬品創製を目指したプロテインエンジニアリング2013
- Author(s)
  植田　正
- Organizer
  第86回日本生化学会大会（シンポジウム）
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23655160
[Presentation] NMRを用いたラットP2X4受容体ヘッドドメインと金属イオンとの相互作用解析2013
- Author(s)
  井川達彦, 阿部義人, 白石充典, 津田誠, 井上和秀, 植田正
- Organizer
  第日本蛋白質科学会
- Place of Presentation
  とりぎん会館（鳥取市）
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] ラットP2X4受容体 Head ドメインの構造および機能解析2012
- Author(s)
  井川達弘, 阿部義人, 白石充典, 津田誠, 井上和秀, 植田正
- Organizer
  第12回日本蛋白質科学会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] NMRを用いたラットP2X4受容体headドメインの構造決定およびリガンド相互作用解析2012
- Author(s)
  井川達弘、阿部義人、白石充典、津田　誠、井上和秀、植田　正
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] NMR を用いたラットP2X4受容体headドメインの構造決定およびリガンド相互作用解析2012
- Author(s)
  井川達弘, 阿部義人, 白石充典, 津田誠,井上和秀, 植田正
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場・マリンメッセ(福岡市)
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] バイオ医薬品の創製とプロテインエンジニアリング2012
- Author(s)
  阿部義人、植田正
- Organizer
  北海道大学薬学部ファーマサイエンスフォーラム
- Place of Presentation
  北海道大学薬学部
- Year and Date
  2012-07-25
- Data Source
  KAKENHI-PROJECT-23655160
[Presentation] ラットP2X4受容体Headドメインの構造および機能解析2012
- Author(s)
  井川達弘、阿部義人、白石充典、津田　誠、井上和秀、植田　正
- Organizer
  第12回日本蛋白質科学会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] ヒトP2X4受容体細胞外ドメインを認識するモノクロナール抗体の作製2011
- Author(s)
  望月志保、白石充典、阿部義人、津田誠、井上和秀、植田正
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都国際会館(京都市)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] 抗ラット P2X4 抗体の抗原認識機構2011
- Author(s)
  井川達弘, 阿部義人, 東貞行, 白石充典, 津田誠, 田中宏幸, 井上和秀, 植田正
- Organizer
  第11回日本蛋白質科学会
- Place of Presentation
  ホテル阪急エキスポパーク(吹田市)
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] ヒト P2X4 受容体細胞外ドメインを認識するモノクローナル抗体の作製2011
- Author(s)
  望月志保, 白石充典, 阿部義人, 津田誠, 井上和秀, 植田正
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都国際会議場(京都市)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] 抗ラットP2X4抗体の抗原認識機構2011
- Author(s)
  井川達彦、阿部義人、東貞行、白石充典、津田誠、田中宏幸、井上和秀、植田正
- Organizer
  第11回日本蛋白質科学会
- Place of Presentation
  ホテル阪急エキスポパーク(大阪府吹田市)
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] Gly-Pro配列導入によるケトアミンオキシダーゼの安定性評価2010
- Author(s)
  末吉彩、大栗誉敏、黒木暁彦、植田正
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市桃太郎アリーナ
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20590579
[Presentation] Gly-Pro 配列導入によるケトアミンオキシダーゼの安定性評価2010
- Author(s)
  末吉彩, 植田正, 他
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20590579

1. IMOTO Taiji (90038282)

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
2. ABE Yoshito (60315091)

# of Collaborated Projects: 9 results

# of Collaborated Products: 23 results
3. SHIROISH Mitsunori (00380527)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
4. KATAYAMA Tsutomu (70264059)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
5. HASHIMOTO Yoshio (50253472)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. HAMASE Kenji (10284522)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. ITO Hiro-O (40213079)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KOYANAGI Satoru (60330932)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. AISO Sadakazu (60138013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. INOUE Kazuhide (80124379)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
11. TSUDA Makoto (40373394)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
12. KURUMIZAKA Hitoshi (80300870)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. ASO Mariko (30201891)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 伊東祐二 (60223195)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 門司晃 (00294942)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. 日下部宜宏 (30253595)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. 宗孝紀 (60294964)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
18. OHKURI Takatoshi (70346807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. SHIOI Seijiro (80423531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. TANAKA Hiroyuki (30253470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
21. SAITO Hidetoshi (90444794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. ENDO Fumio (00176801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YAMADA Hidenori (80037613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. KAWANO Keiichi (10136492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. HIRATA Masato (60136471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. INOUE Masakazu (30028740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. IZUHARA Kenji (00270463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. SU'ETSUGU Masayuki (00363341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
29. 田中正一 (00227175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 末宗洋 (20095897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 宮本智文 (40182050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 栗原正明 (20205206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. KUROKI Ryota

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. ENDO Atsushi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. KEYAMURA Kenji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 三田肇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 岡村匡史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 阿部修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 津田一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ueda Tadashi 植田 正

UEDA Tadashi 植田 正

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Fundamental study on depression of Anti-Drug Antibodies by use of immune tolerancePrincipal Investigator

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Fundamental Study on Preparations for Therapeutic Antibodies with Less Productions of Anti-Drug AntibodiesPrincipal Investigator

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Establishment of research foundation on "objective pain assessment" using animal models suffering from neuropathic painPrincipal Investigator

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Study on the development of molecules for depressing neuropathic pain based on tertiary structure of human P2X4 receptorPrincipal Investigator

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Development of Fab molecule with the stable scaffold for next generationPrincipal Investigator

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Improved function of ketoamine oxidase for clinical examination reagent of diabetes by use of multiple approachesPrincipal Investigator

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核磁気共鳴装置を用いたβアミロイドペプチドのリン酸イオンによる凝集抑制機構の解明Principal Investigator

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Ueda Tadashi 植田正

UEDA Tadashi 植田正