Kanno Jun 菅野純

… Alternative Names

菅野純カンノジュン

KANNO Jun 菅野純

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Researcher Number	90186172
Other IDs	https://orcid.org/0000-0001-5191-621X
External Links
Affiliation (Current)	2025: 国立医薬品食品衛生研究所, 毒性部, 客員研究員 2025: 特定非営利活動法人システム・バイオロジー研究機構, その他部局など, 客員上席研究員
Affiliation (based on the past Project Information) *help	2015: 国立医薬品食品衛生研究所, 毒性部, 部長 2009: 国立医薬品食品衛生研究所, 毒性部, 部長 2004 – 2006: 国立医薬品食品衛生研究所, 毒性部, 部長 2001: 国立医薬品食品衛生研究所, 毒性部・第1室, 室長 1998 – 2000: National Institute of Health Sciences Div.of Cellular and Molecular Toxicology S, 毒性部, 室長 … More 1995 – 1996: 東京医科歯科大学, 医学部, 講師 1994: 東京医科歯科大学, 医学部, 助手 1990: 東京医科歯科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Science and Engineering Except Principal Investigator Experimental pathology / Pediatrics / Medical pharmacy / Biological Sciences / 広領域
Keywords	Principal Investigator 網羅的遺伝子発現解析 / Diethylstilbestrol / ニューロスフェア / 神経幹細胞 / エストロジェン受容体 / 内分泌攪乱物質 Except Principal Investigator parchorin / apoptosis / gap junction / アポトーシス … More / ギャップ結合細胞間連絡 / ペンタクロロフェノール / p53 / T細胞 / 胸腺 / 脳 / Epstein症候群 / Myosin IIA / podocytc / 巣状糸球体硬化症 / ネフローゼ症候群 / nephrotic syndrome / Epstein syndrome / myosin IIA / podocyte / transcriptome / water movement / gastric acid secretion / knockout mouse / コンディショナルノックアウト / トランスクリプトーム / 唾液分泌 / 胃酸分泌 / ノックアウトマウス / hemopoietic stem cell / pentachlorophenol / connexin / promotion / Gap junction(細胞間連絡) / 造血幹細胞 / コネクシン / 発がんプロモーター / pentachlorohenol / ギャップ結合細胞間コミュニケーション / Rat / Mouse / Thymus / Hypothalamus / Cytokine receptor / Immune system / Endocrine system / Nervous system / 加齢 / ICAM-1 / TNFα / ホルモン / サイトカイン / 脾臓 / ラット / マウス / サイトカイン受容体 / 視床下部 / 免疫系 / 内分泌系 / 神経系 / Notch-YFP / Dll1 / Lunatic Fringe / Lunatic Fring / Pofut1 / キメラ解析 / D111 / Notchシグナル / 分節境界 / Hes7 / L-fng / 未分節中胚葉 / Tbx6 / Mesp2 / 体節時計 / 脊椎骨 / Notchシグナ / 体節形成 / 情報伝達物質 / 免疫 / 炎症性肉芽 / 慢性臓器炎 / 発癌促進作用 / 大腸癌 / 潰瘍性大腸炎 Less

ヒトiPSおよび新規遺伝子改変マウスを用いたネフローゼ症候群の病因解明
- Principal Investigator
  
  関根孝司
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Toho University
The mechanism of somite segmentation with periodic patterning
- Principal Investigator
  
  SAGA Yumiko
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
Pathophysiological Analysis of Parchorin, Specifically Expressed in Water-Transporting Tissues
- Principal Investigator
  
  URUSHIDANI Tetsuro
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Doshisha Women's College of Liberal Arts
  National Institute of Health Sciences
DES等内分泌撹乱物質の胎児神経幹細胞スフェア形成阻害の分子メカニズム解析Principal Investigator
- Principal Investigator
  
  菅野純
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  National Institute of Health Sciences
Blocks of cell communication and apoptosis in carcinogenesis
- Principal Investigator
  
  INOUE Tohru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Experimental pathology
- Research Institution
  National Institute of Health Sciences
p53 null mice and chemical oncogenesis for promotion study
- Principal Investigator
  
  INOUE Tohru
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Experimental pathology
- Research Institution
  National Institute of Health Sciences
AN EXPERIMENTAL PATHOLOGICAL STUDY ON THE INTERACTION AMONG NERVOUS,ENDOCRINE AND IMMUNE SYSTEMS.
- Principal Investigator
  
  HIROKAWA Katsuiku
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  TOKYO MEDICAL AND DENTAL UNIVERSITY
脳と免疫系のクロストークとその加齢変化に関する分子生物学的研究
- Principal Investigator
  
  HIROKAWA Katsuiku
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  Tokyo Medical and Dental University
慢性潰瘍性大腸炎による大腸発癌促進作用
- Principal Investigator
  
  岡安勲
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Medical and Dental University

All 2015 2010 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite.2010
- Author(s)
  Oginuma M, Takahashi Y, Kitajima S, Kiso M, Kanno J, Kimura A, Saga Y
- Journal Title
  
  Development.
- Data Source
  KAKENHI-PROJECT-17082010
[Journal Article] Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm (PSM) specific enhancer of Mesp.2008
- Author(s)
  Yasuhiko Y, Kitajima S, Takahashi Y, Oginuma M, Kagiwada H, Kanno J, Saga Y
- Journal Title
  
  Development 135
  
  Pages: 3511-9
- Data Source
  KAKENHI-PROJECT-17082010
[Journal Article] Transcription factors Mesp2 and Paraxis have critical roles in axial musculoskeletal formation.2007
- Author(s)
  Takahashi Y, Takagi A, Hiraoka S, Koseki H, Kanno J, Rawls A, Saga Y
- Journal Title
  
  Dev Dyn 236
  
  Pages: 1484-94
- Data Source
  KAKENHI-PROJECT-17082010
[Journal Article] The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite.2007
- Author(s)
  Morimoto M, Sasaki N, Oginuma M, Kiso M, Igarashi K, Aizaki K, Kanno J, Saga Y
- Journal Title
  
  Development 134
  
  Pages: 1561-9
- Data Source
  KAKENHI-PROJECT-17082010
[Journal Article] Tbx6-mediated Notch signaling controls somite-specific Mesp2 expression.2006
- Author(s)
  Yasuhiko Y, Haraguchi S., Kitajima S., Takahashi Y., Jun Kanno J., Saga Y.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 103
  
  Pages: 3651-3656
- Data Source
  KAKENHI-PROJECT-17082010
[Journal Article] Tbx6-mediated Notch signaling controls somite-specific Mesp2 expression.2006
- Author(s)
  Yasuhiko Y., Haraguchi S., Kitajima S., Takahashi Y, Kanno J. Saga, Y.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 103
  
  Pages: 3651-3656
- Data Source
  KAKENHI-PROJECT-17082010
[Presentation] Rab23, a negative regulator of Shh signaling, modulates intervertebral discvertebral body (IVDNB) patterning and neural arch morphogenesis in mouse vertebral column formation.2015
- Author(s)
  Takahashi Y, Yasuhiko Y, Koike-Ikeno E, Kanno J
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04880
[Presentation] 体節形成に関わる転写因子Mesp2の発現制御における転写因子Tbx6の役割2006
- Author(s)
  安彦行人, 原口清輝, 北嶋聡, 高橋雄, 菅野純, 相賀裕美子
- Organizer
  日本発生生物学会第39回大会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-17082010
[Presentation] 体節形成におけるストライプパターンの形成には未分節中胚葉前方におけるNotchシグナルのネガティブフィードバックが本質的に重要である.2005
- Author(s)
  高橋雄, 北嶋聡, 菅野純, 相賀裕美子
- Organizer
  日本発生生物学会第38回大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-17082010
[Presentation] NotchシグナルはTbx6の依存的にMesp2発現を活性化する.2005
- Author(s)
  安彦行人, 原口清輝, 高橋雄, 菅野純, 相賀裕美子
- Organizer
  第28回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17082010
[Presentation] NotchシグナルおよびTbx6によるMesp2発現制御機構の解析2005
- Author(s)
  安彦行人, 原口清輝, 菅野純, 相賀裕美子
- Organizer
  日本発生生物学会第38回大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-17082010

1. HIROKAWA Katsuiku (00014093)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. NEMOTO Tetsuo (70242203)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KITAGAWA Masanobu (10177834)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. YASUHIKO Yukuto (40370944)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. INOUE Tohru (50100110)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SAI Kimie (20195960)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 大橋健一 (40231203)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TROSKO James E.

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SAGA Yumiko (50221271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
10. KOKUBO Hiroki (10270480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MISTUI Kaoru (40324975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TAKAHASHI Yu (60321858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
13. KITAJIMA Satoshi (30270622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
14. UTSUYAMA Masanori (70167287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HASEGAWA Ryuichi (50112496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. HIRABAYASHI Yoko (30291115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. URUSHIDANI Tetsuro (40262159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 岡安勲 (20014342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 大草敏史 (50160445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 相崎健一 (40322086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 五十嵐勝秀 (30342885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 関根孝司 (50255402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 松下正 (30314008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 國島伸治 (60373495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 西中村隆一 (70291309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 栗原秀剛 (80311976)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. KANG Kyung-sun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. TROSKOJAMES ジェームス・イー・

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kanno Jun 菅野 純

菅野 純 カンノ ジュン

KANNO Jun 菅野 純

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DES等内分泌撹乱物質の胎児神経幹細胞スフェア形成阻害の分子メカニズム解析Principal Investigator

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[Journal Article] The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite.2010

Author(s)

Journal Title

Data Source

[Journal Article] Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm (PSM) specific enhancer of Mesp.2008

Author(s)

Journal Title

Data Source

[Journal Article] Transcription factors Mesp2 and Paraxis have critical roles in axial musculoskeletal formation.2007

Author(s)

Journal Title

Data Source

[Journal Article] The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite.2007

Author(s)

Journal Title

Data Source

[Journal Article] Tbx6-mediated Notch signaling controls somite-specific Mesp2 expression.2006

Author(s)

Journal Title

Data Source

[Journal Article] Tbx6-mediated Notch signaling controls somite-specific Mesp2 expression.2006

Author(s)

Journal Title

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[Presentation] Rab23, a negative regulator of Shh signaling, modulates intervertebral discvertebral body (IVDNB) patterning and neural arch morphogenesis in mouse vertebral column formation.2015

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Organizer

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Kanno Jun 菅野純

菅野純カンノジュン

KANNO Jun 菅野純