ISHIWATA Toshiyuki 石渡俊行

Researcher Number	90203041
Other IDs	https://orcid.org/0000-0002-4180-0069
Affiliation (Current)	2025: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長
Affiliation (based on the past Project Information) *help	2015 – 2024: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 2015: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), その他部局等, その他 2007 – 2014: Nippon Medical School, Faculty of Medicine, Associate Professor 2004 – 2007: Nippon Medical School, Medicine, Associate Professor, 医学部, 助教授 2001 – 2003: 日本医科大学, 医学部, 講師 1999: Nippon Medical School Dept. Patology, Assistant, 医学部, 助手
Review Section/Research Field	Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / Gastroenterology / Gastroenterology Except Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 49020:Human pathology-related / Neo-Gerontology / 内科学一般 / Veterinary medical science / Experimental pathology
Keywords	Principal Investigator FGF-7 / pancreatitis / 膵癌 / 糖鎖 / FGF-10 / nestin / 癌幹細胞 / SNP / Lumican / KGFR … More / pancreatic regeneration / fibroblast growth factor / 線維芽細胞増殖因子 / Western blot analysis / Immunohistochemistry / Keratinocyte growth factor receptor / fibroblast growth factor (FGF)-10 / Nestin / 分子標的治療 / E-cadherin / 培養細胞株 / 遊走能 / 膵星細胞 / 3次元培養 / 上皮間葉系形質 / エクソーム解析 / 高齢者がん / FGFR-4阻害剤 / 個別化治療 / FGFR-4 / glycosylation / Growth factor / pancreatic cancer / 細胞増殖因子 / 膵臓癌 / 膵再生 / KFGR / Keratinocyte growth factor / 慢性膵炎 / microRNA / スフェア形成能 / miRNA / ESRP-1 / FGFR2 IIIc / 細胞増殖因子受容体 / FGFR2IIIc / 線維芽細胞増殖因子受容体 / 因子受容体 / 線維芽細胞増殖 / 選択的スプライシング / siRNA / ESRP1 / FGFR-2 IIIc … More Except Principal Investigator 膵癌 / lumican / 癌幹細胞 / pancreatitis / cell growth / proteoglycan / pancreatic cancer / がん幹細胞 / nestin / 幹細胞 / EMT / プロテオーム解析 / 膵臓がん / テロメア / FGF / AR42J / Betacellulin / Activin-A / 転写因子 / progenitor cell / 細胞増殖 / small-leucine-rich proteoglycan / neuroendocrine cell carcinoma / carcinoid / 浸潤 / 膵臓癌 / ３次元培養 / スフェロイド / 組織Q-FISH法 / 線維化マーカー / 細胞老化関連マーカー / 小児肝移植 / 消化管 / 神経内分泌腫瘍 / 位相差顕微鏡 / 走査型電子顕微鏡 / 消化管神経内分泌腫瘍 / 3D培養 / 遺伝子変異 / 免疫組織化学 / 遺伝子検査 / 免疫チェックポイント阻害剤 / PD-L1 / 精度管理 / KRAS遺伝子 / マイクロサテライト不安定性 / 高齢者 / 胃癌 / 多様性 / geneticin / 発現細胞 / 表面糖鎖 / 細胞表面糖鎖 / 膵癌細胞 / 糖鎖 / シングルセル解析 / Vimentin / E-cadherin / SEM / スフェア / 発がん / 解剖 / 病理 / 糖尿病 / 癌 / 膵臓 / 一塩基多型 / SOX9 / 前駆細胞 / 加齢 / 組織前駆細胞 / 老化 / human bone marrow mesenchvmal stem cells / insulin / 骨髄幹細胞 / 骨髄間葉系肝細胞 / インスリン / immunohistochemistry / 免疫組織化学染色 / プロテオグリカン / 膵炎 / Development and differentiation / Regenerative therapy / FGF-10 / FGF-7 / 急性膵炎 / 膵前駆細胞 / 膵再生 / 発生、分化 / 再生医学 / small leucine-rich proteoglycan / Disease modifying antirheumatic drugs (DMARDs) / Cultured synoviocytes / Endostatin / Basic fibroblast growth factor (b-FGF) / Vascular endothelial growth factor (VEGF) / Angiogenesis / Rheumatoid Arthritis / IL-6 / 疾患修飾性抗リウマチ剤 / 疾患修飾性抗リウマチ剤(DMARDs) / 滑膜培養細胞 / endostatin / b-FGF / VEGF / 血管新生 / 関節リウマチ / 接着能 / 浸潤能 / Bcl-xL / アポトーシス / 抗癌剤感受性 / ゲムシタビン / STAT5b / STAT5ｂ / ゲムシタビン抵抗性 / 接着 / STAT5 / 乳癌 / 横紋筋肉腫 / 炎症性乳癌 / 自己複製能 / がん / 犬 / 遊走 / 増殖 / 転移 / リン酸化 / 細胞骨格 / 癌幹細胞マーカー / 前癌病変 / 再生医療 / 細胞接着 / インスリン分泌 / 3次元培養 / 膵β細胞 / MMP / 子宮内膜癌 / MMP-9 / 静脈侵襲 / VEGF-A / 大腸癌 / ケラチノサイト増殖因子 Less

Prognostic biomarkers of allograft in pediatric liver transplantation
- Principal Investigator
  
  眞田幸弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Jichi Medical University
Proteomic analysis of pancreatic cancer cells in 3D culture: Search for personalized medicine and early diagnosis methods
- Principal Investigator
  
  志智優樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
高齢者胃癌の遺伝子異常に基づく病態解明と治療戦略
- Principal Investigator
  
  新井富生
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Molecular biological analysis of gastrointestinal neuroendocrine tumors and development of new therapeutic drugs
- Principal Investigator
  
  進士誠一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Nippon Medical School
Development of novel therapies by regulating epithelial and mesenchymal features of pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  石渡俊行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
New therapeutic methods by variability control of pancreatic cancer cells
- Principal Investigator
  
  志智優樹
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
幹細胞表面特異的糖鎖を標的とした膵癌の新規治療法の開発
- Principal Investigator
  
  五味不二也
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Development of early diagnosis and new treatments for pancreatic cancer using cancer stem cell-specific glycansPrincipal Investigator
- Principal Investigator
  
  Ishiwata Toshiyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Personalized therapy for pancreatic cancer focused on FGFR-4, a novel molecular targetPrincipal Investigator
- Principal Investigator
  
  Ishiwata Toshiyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Mechanisms of aging in the tissue progenitor cells and tissue regeneration
- Principal Investigator
  
  Matsuda Yoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neo-Gerontology
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Identification and clinical application of cancer stem cells derived from canine refractory cancers
- Principal Investigator
  
  Michishita Masaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Nippon Veterinary and Life Science University
The biological role and signal pathway of Stat5 in pancreatic cancer
- Principal Investigator
  
  Matsushita Akira
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nippon Medical School
Regulation of nestin using microRNA: Examination for clinical application of pancreatic cancer therapyPrincipal Investigator
- Principal Investigator
  
  Ishiwata Toshiyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  Nippon Medical School
Inhibition of nestin phosphorylation in pancreatic cancer cells
- Principal Investigator
  
  Matsuda Yoko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Identification of Pancreatic Cancer Stem Cells and Development of Novel Therapeutic Strategies using Stem Cell Markers
- Principal Investigator
  
  NAITO Zenya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Nippon Medical School
Treatment strategy of pancreatic cancer by regulating FGFR2IIIc isoformPrincipal Investigator
- Principal Investigator
  
  ISHIWATA Toshiyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nippon Medical School
Investigation of differentiation of extrapancreatic stem cells to pancreatic β-cells
- Principal Investigator
  
  KUDO Mitsuhiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nippon Medical School
Novel strategy for pancreatic cancer treatment, using keratinocyte growth factor receptor
- Principal Investigator
  
  NAITO Zenya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nippon Medical School
Inhibitory effect of lumican on the growth factor-mediated pancreatic cancer cell growthPrincipal Investigator
- Principal Investigator
  
  ISHIWATA Toshiyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nippon Medical School
Ideniification and isolation of pancreatic stem cells
- Principal Investigator
  
  KUDO Mitsuhiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nippon Medical School
Role of lumican for cell growth and differentiation in pancreatic cancer
- Principal Investigator
  
  NAITO Zenya
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nippon Medical School
Identification and application of pancreatic internal and external progenitor cell having differentiation potency to β-cells
- Principal Investigator
  
  KUDO Mitsuhiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nippon Medical School
Research of pancreatic regeneration by fibroblast growth factor -7 and -10Principal Investigator
- Principal Investigator
  
  ISHIWATA Toshiyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nippon Medical School
Role of lumican in pancreatic cancer and chronic pancreatits-like lesion in pancreatic cancer
- Principal Investigator
  
  NAITO Zenya
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nippon Medical School
Expression and the role of fibroblast growth factor (FGF)-10 in chronic pancreatitisPrincipal Investigator
- Principal Investigator
  
  ISHIWATA Toshiyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nippon Medical School
関節リウマチのサイトカインおよび血管増殖因子抑制効果に関する基礎的研究-サイトカインおよびVEGFアンチセンス療法による新しい治療戦略-
- Principal Investigator
  
  NAGASHIMA Masakazu
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  NIPPON MEDICAL SCHOOL

[Journal Article] Clinicopathological and molecular characteristics of gastric papillary adenocarcinoma2023
- Author(s)
  Arai Tomio、Komatsu Akiko、Kanazawa Nobuo、Nonaka Keisuke、Ishiwata Toshiyuki
- Journal Title
  
  Pathology International
  
  Volume: 73 Issue: 8 Pages: 358-366
- DOI
  10.1111/pin.13345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06972, KAKENHI-PROJECT-19K07428
[Journal Article] Artificial intelligence-based analysis of time-lapse images of sphere formation and process of plate adhesion and spread of pancreatic cancer cells2023
- Author(s)
  Shichi Yuuki、Gomi Fujiya、Hasegawa Yasuko、Nonaka Keisuke、Shinji Seiichi、Takahashi Kimimasa、Ishiwata Toshiyuki
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 11 Pages: 1290753-1290753
- DOI
  10.3389/fcell.2023.1290753
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08744, KAKENHI-PROJECT-21K08764, KAKENHI-PROJECT-22K08882
[Journal Article] Multiple cystic sphere formation from PK-8 cells in three-dimensional culture2022
- Author(s)
  Yuuki Shichi, Fujiya Gomi, Yoshibumi Ueda, Keisuke Nonaka, Fumio Hasegawa, Yasuko Hasegawa, Nae Hinata, Hisashi Yoshimura, Masami Yamamoto, Kimimasa Takahashi, Tomio Arai, Toshiyuki Ishiwata
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 32 Pages: 101339-101339
- DOI
  10.1016/j.bbrep.2022.101339
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06408, KAKENHI-PROJECT-21K08744, KAKENHI-PROJECT-21K08764, KAKENHI-PROJECT-22K08882
[Journal Article] Gp130-Mediated STAT3 Activation Contributes to the Aggressiveness of Pancreatic Cancer through H19 Long Non-Coding RNA Expression2022
- Author(s)
  Sasaki Norihiko、Hirano Kazumi、Shichi Yuuki、Gomi Fujiya、Yoshimura Hisashi、Matsushita Akira、Toyoda Masashi、Ishiwata Toshiyuki
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 9 Pages: 2055-2055
- DOI
  10.3390/cancers14092055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-21K08744, KAKENHI-PROJECT-21K08764, KAKENHI-PROJECT-22K06013, KAKENHI-PROJECT-18K14597
[Journal Article] Epithelial and Mesenchymal Features of Pancreatic Ductal Adenocarcinoma Cell Lines in Two- and Three-Dimensional Cultures2022
- Author(s)
  Shichi Yuuki、Gomi Fujiya、Sasaki Norihiko、Nonaka Keisuke、Arai Tomio、Ishiwata Toshiyuki
- Journal Title
  
  Journal of Personalized Medicine
  
  Volume: 12 Issue: 5 Pages: 746-746
- DOI
  10.3390/jpm12050746
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-21K08744, KAKENHI-PROJECT-21K08764
[Journal Article] TGF-β1 increases cellular invasion of colorectal neuroendocrine carcinoma cell line through partial epithelial-mesenchymal transition2022
- Author(s)
  Sasaki Norihiko、Shinji Seiichi、Shichi Yuuki、Ishiwata Toshiyuki、Arai Tomio、Yamada Takeshi、Takahashi Goro、Ohta Ryo、Sonoda Hiromichi、Matsuda Akihisa、Iwai Takuma、Takeda Kohki、Yonaga Kazuhide、Ueda Koji、Kuriyama Sho、Miyasaka Toshimitsu、Yoshida Hiroshi
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 30 Pages: 101239-101239
- DOI
  10.1016/j.bbrep.2022.101239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-19K11759
[Journal Article] A New Anorectal Melanoma Cell Line Derived from a Primary Human Rectal Tumor2022
- Author(s)
  Shinji Seiichi、Shichi Yuuki、Yamada Takeshi、Takahashi Goro、Ohta Ryo、Sonoda Hiromichi、Matsuda Akihisa、Yonaga Kazuhide、Iwai Takuma、Takeda Kohki、Ueda Koji、Kuriyama Sho、Miyasaka Toshimitsu、Ueda Yoshibumi、Sasaki Norihiko、Takahashi Kimimasa、Ohashi Ryuji、Ishiwata Toshiyuki、Arai Tomio、Yoshida Hiroshi
- Journal Title
  
  Journal of Nippon Medical School
  
  Volume: 89 Issue: 4 Pages: 368-376
- DOI
  10.1272/jnms.JNMS.2022_89-402
- NAID
  130008144205
- ISSN
  1345-4676, 1347-3409
- Year and Date
  2022-08-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07685, KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-19K11759
[Journal Article] Polyvinyl alcohol increased growth, migration, invasion, and sphere size in the PK-8 pancreatic ductal adenocarcinoma cell line2021
- Author(s)
  Fujiya Gomi, Norihiko Sasaki, Yuuki Shichi, Fuuka Minami, Seiichi Shinji, Masashi Toyoda, Toshiyuki Ishiwata
- Journal Title
  
  Heliyon
  
  Volume: 7 Issue: 2 Pages: e06182-e06182
- DOI
  10.1016/j.heliyon.2021.e06182
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-19K11759, KAKENHI-PROJECT-21K08764
[Journal Article] Gangliosides as signaling regulators in cancer2021
- Author(s)
  Sasaki Norihiko , Toyoda Masashi , Ishiwata Toshiyuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 10 Pages: 5076-5076
- DOI
  10.3390/ijms22105076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-19K11759
[Journal Article] Morphofunctional analysis of human pancreatic cancer cell lines in 2- and 3-dimensional cultures2021
- Author(s)
  Minami Fuuka, Sasaki Norihiko, Shichi Yuuki, Gomi Fujiya, Michishita Masaki, Ohkusu-Tsukada Kozo, Toyoda Masashi, Takahashi Kimimasa, Ishiwata Toshiyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 6775-6775
- DOI
  10.1038/s41598-021-86028-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-19K11759, KAKENHI-PROJECT-19H03132, KAKENHI-PROJECT-21K08764
[Journal Article] Characterization of the metastatic potential of the floating cell component of MIA PaCa-2, a human pancreatic cancer cell line2020
- Author(s)
  Sasaki Norihiko、Gomi Fujiya、Hasegawa Fumio、Hirano Kazumi、Fujiwara Masakazu、Toyoda Masashi、Ishiwata Toshiyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 522 Issue: 4 Pages: 881-888
- DOI
  10.1016/j.bbrc.2019.11.120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-19K11759
[Journal Article] FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer2020
- Author(s)
  Sasaki N, Gomi F, Yoshimura H, Yamamoto M, Matsuda Y, Michishita M, Hatakeyama H, Kawano Y, Toyoda M, Korc M, Ishiwata T.
- Journal Title
  
  Cancers (Basel)
  
  Volume: 12 Issue: 10 Pages: 2976-2976
- DOI
  10.3390/cancers12102976
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06391, KAKENHI-PROJECT-19K06408, KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-19K11759
[Journal Article] Ganglioside GM2, highly expressed in the MIA PaCa-2 pancreatic ductal adenocarcinoma cell line, is correlated with growth, invasion, and advanced stage2019
- Author(s)
  Sasaki Norihiko、Hirabayashi Kenichi、Michishita Masaki、Takahashi Kimimasa、Hasegawa Fumio、Gomi Fujiya、Itakura Yoko、Nakamura Naoya、Toyoda Masashi、Ishiwata Toshiyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 19369-19369
- DOI
  10.1038/s41598-019-55867-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06391, KAKENHI-PROJECT-19K09207, KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-19K11759
[Journal Article] The stem cell-specific intermediate filament nestin missense variation p.A1199P is associated with pancreatic cancer2019
- Author(s)
  Matsuda Yoko、Tanaka Masashi、Sawabe Motoji、Mori Seijiro、Muramatsu Masaaki、Naka Mieno Makiko、Ishiwata Toshiyuki、Arai Tomio
- Journal Title
  
  Oncology Letters
  
  Volume: 17 Pages: 4647-54
- DOI
  10.3892/ol.2019.10106
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08718, KAKENHI-PROJECT-16H01872, KAKENHI-PROJECT-16KT0125
[Journal Article] Reduced expression of the H19 long non-coding RNA inhibits pancreatic cancer metastasis2018
- Author(s)
  Yoshimura Hisashi、Matsuda Yoko、Yamamoto Masami、Michishita Masaki、Takahashi Kimimasa、Sasaki Norihiko、Ishikawa Naoshi、Aida Junko、Takubo Kaiyo、Arai Tomio、Ishiwata Toshiyuki
- Journal Title
  
  Laboratory Investigation
  
  Volume: 印刷中 Issue: 6 Pages: 814-824
- DOI
  10.1038/s41374-018-0048-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-16K10613
[Journal Article] Pancreatic cancer stem cells: features and detection methods2018
- Author(s)
  Ishiwata Toshiyuki、Matsuda Yoko、Yoshimura Hisashi、Sasaki Norihiko、Ishiwata Shunji、Ishikawa Naoshi、Takubo Kaiyo、Arai Tomio、Aida Junko
- Journal Title
  
  Pathology & Oncology Research
  
  Volume: 24 Issue: 4 Pages: 797-805
- DOI
  10.1007/s12253-018-0420-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-16K10613
[Journal Article] <i>H19</i> long non-coding RNA contributes to sphere formation and invasion through regulation of CD24 and integrin expression in pancreatic cancer cells2018
- Author(s)
  Sasaki Norihiko、Toyoda Masashi、Yoshimura Hisashi、Matsuda Yoko、Arai Tomio、Takubo Kaiyo、Aida Junko、Ishiwata Toshiyuki
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 78 Pages: 34719-34734
- DOI
  10.18632/oncotarget.26176
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-18K14597, KAKENHI-PROJECT-16K10613
[Journal Article] Stemness and anti-cancer drug resistance in ATP-binding cassette subfamily G member 2 highly expressed pancreatic cancer is induced in 3D culture conditions2018
- Author(s)
  Sasaki Norihiko、Ishiwata Toshiyuki、Hasegawa Fumio、Michishita Masaki、Kawai Hiroki、Matsuda Yoko、Arai Tomio、Ishikawa Naoshi、Aida Junko、Takubo Kaiyo、Toyoda Masashi
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 4 Pages: 1135-1146
- DOI
  10.1111/cas.13533
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-16K10613
[Journal Article] Clinicopathological characteristics of distant metastases of adenocarcinoma, squamous cell carcinoma and urothelial carcinoma : An autopsy study of older Japanese patients.2018
- Author(s)
  Matsuda Y, Seki A, Nonaka K, Kakizaki M, Wang T, Aida J, Ishikawa N, Nakano Y, Kaneda D, Takata T, Takahashi-Fujigasaki J, Murayama S, Takubo K, Ishiwata T, Sawabe M, Arai T.
- Journal Title
  
  Geriatr Gerontol Int.
  
  Volume: 18 Issue: 2 Pages: 211-215
- DOI
  10.1111/ggi.13165
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16KT0125
[Journal Article] Abnormal immunolabelling of SMAD 4 in cell block specimens to distinguish malignant and benign pancreatic cells2018
- Author(s)
  Matsuda Yoko、Esaka Shikine、Suzuki Akemi、Hamashima Yuri、Imaizumi Masayuki、Matsukawa Miho、Fujii Yuko、Aida Junko、Takubo Kaiyo、Ishiwata Toshiyuki、Nishimura Makoto、Arai Tomio
- Journal Title
  
  Cytopathology
  
  Volume: 30 Issue: 2 Pages: 201-208
- DOI
  10.1111/cyt.12653
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0125
[Journal Article] Telomere length determined by the fluorescence in?situ hybridisation distinguishes malignant and benign cells in cytological specimens2018
- Author(s)
  Matsuda Y.、Suzuki A.、Esaka S.、Hamashima Y.、Imaizumi M.、Kinoshita M.、Shirahata H.、Kiso Y.、Kojima H.、Matsukawa M.、Fujii Y.、Ishikawa N.、Aida J.、Takubo K.、Ishiwata T.、Nishimura M.、Arai T.
- Journal Title
  
  Cytopathology
  
  Volume: 29 Issue: 3 Pages: 262-266
- DOI
  10.1111/cyt.12535
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08414, KAKENHI-PROJECT-16KT0125
[Journal Article] Identification of tumor-initiating cells derived from two canine rhabdomyosarcoma cell lines2017
- Author(s)
  Kishimoto TE, Yashima S, Nakahira R, Onozawa E, Azakami D, Ujike M, Ochiai K, Ishiwata T, Takahashi K, Michishita M.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 79 Issue: 7 Pages: 1155-1162
- DOI
  10.1292/jvms.16-0412
- NAID
  130005712508
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26292161
[Journal Article] Cutaneous Angiolymphoid Hyperplasia in a Dog2017
- Author(s)
  Michishita M, Katori Y, Sasaki H, Obara RD, Furumoto R, Kato M, Nakahira R, Yoshimura H, Soeta S, Ishiwata T, Takahashi K
- Journal Title
  
  Journal of Comparative Pathology
  
  Volume: 157 Issue: 1 Pages: 57-60
- DOI
  10.1016/j.jcpa.2017.05.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26292161
[Journal Article] Disseminated histiocytic sarcoma with hemophagocytosis in a rabbit2017
- Author(s)
  Ishimori M, Michishita M, Yoshimura H, Azakami D, Ochiai K, Ishiwata T, Takahashi K
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 79 Issue: 9 Pages: 1503-1506
- DOI
  10.1292/jvms.17-0297
- NAID
  130006073235
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26292161
[Journal Article] Electron microscopic analysis of different cell types in human pancreatic cancer spheres2017
- Author(s)
  Ishiwata Toshiyuki、Hasegawa Fumio、Michishita Masaki、Sasaki Norihiko、Ishikawa Naoshi、Takubo Kaiyo、Matsuda Yoko、Arai Tomio、Aida Junko
- Journal Title
  
  Oncology Letters
  
  Volume: 15 Pages: 2485-2490
- DOI
  10.3892/ol.2017.7554
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-16K10613
[Journal Article] Pancreatic Colloid Carcinoma in an Elderly Cat2017
- Author(s)
  Hagiwara K.、Michishita M.、Yoshimura H.、Ochiai K.、Azakami D.、Ishiwata T.、Takahashi K.
- Journal Title
  
  Journal of Comparative Pathology
  
  Volume: 157 Issue: 4 Pages: 266-269
- DOI
  10.1016/j.jcpa.2017.08.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26292161
[Journal Article] The Prevalence and Clinicopathological Characteristics of High-Grade Pancreatic Intraepithelial Neoplasia: Autopsy Study Evaluating the Entire Pancreatic Parenchyma.2017
- Author(s)
  1.Matsuda Y, Furukawa T, Yachida S, Nishimura M, Seki A, Nonaka K, Aida J, Takubo K, Ishiwata T, Kimura W, Arai T, Mino-Kenudson M.
- Journal Title
  
  Ｐａｎｃｒｅａｓ
  
  Volume: 46 Issue: 5 Pages: 658-664
- DOI
  10.1097/mpa.0000000000000786
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0125, KAKENHI-PROJECT-26350822, KAKENHI-PROJECT-16K09412
[Journal Article] Clinicopathological features of 15 occult and 178 clinical pancreatic ductal adenocarcinomas in 8339 autopsied elderly patients.2016
- Author(s)
  1.Matsuda Y, Ishiwata T, Yachida S, Suzuki A, Hamashima Y, Hamayasu H, Yoshimura H, Honma N, Aida J, Takubo K, Arai T.
- Journal Title
  
  Pancreas
  
  Volume: 45 Issue: 2 Pages: 234-40
- DOI
  10.1097/mpa.0000000000000447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462127
[Journal Article] Ａｄｍｉｎｉｓｔｒａｔｉｏｎ　ｏｆ　ｓｍａｌｌ　ｉｎｔｅｒｆｅｒｉｎｇ　ＲＮＡ　ｔａｒｇｅｔｉｎｇ　ｈｕｍａｎ　ｎｅｓｔｉｎ　ｉｎｈｉｂｉｔｓ　ｐａｎｃｒｅａｔｉｃ　ｃａｎｃｅｒ　ｃｅｌｌ　ｐｒｏｌｉｆｅｒａｔｉｏｎ　ａｎｄ　ｍｅｔａｓｔａｓｉｓ．2016
- Author(s)
  Ｍａｔｓｕｄａ　Ｙ, Ishiwata T, Yoshimura H, Yamashita S, Ushijima T, Arai T.
- Journal Title
  
  Ｐａｎｃｒｅａｓ
  
  Volume: ４５ Issue: 1 Pages: 93-100
- DOI
  10.1097/mpa.0000000000000427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461027, KAKENHI-PROJECT-25462127
[Journal Article] Mitotic index and multipolar mitosis in routine histologic sections as prognostic markers of pancreatic cancers: A clinicopathological study.2016
- Author(s)
  2.Matsuda Y, Yoshimura H, Ishiwata T, Sumiyoshi H, Matsushita A, Nakamura Y, Aida J, Uchida E, Takubo K, Arai T.
- Journal Title
  
  Pancreatology
  
  Volume: 16 Issue: 1 Pages: 127-32
- DOI
  10.1016/j.pan.2015.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462127
[Journal Article] Characterization of Spontaneous Mammary Tumors in Domestic Djungarian Hamsters (Phodopus sungorus).2015
- Author(s)
  Yoshimura H, Kimura-Tsukada N, Ono Y, Michishita M, Ohkusu-Tsukada K, Matsuda Y, Ishiwata T, Takahashi K.
- Journal Title
  
  Vet Pathol.
  
  Volume: 52(1) Issue: 6 Pages: 1227-1234
- DOI
  10.1177/0300985815583097
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450434, KAKENHI-PROJECT-26292161
[Journal Article] Inhibition of fibroblast growth factor receptor 2 attenuates proliferation and invasion of pancreatic cancer.2014
- Author(s)
  Matsuda Y, Yoshimura H, Suzuki T, Uchida E, Naito Z, Ishiwata T.
- Journal Title
  
  Cancer Science
  
  Volume: 105 Issue: 9 Pages: 1212-1219
- DOI
  10.1111/cas.12470
- Description
  in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J11084, KAKENHI-PROJECT-25461027, KAKENHI-PROJECT-26870622
[Journal Article] Cellular Sources of Tenascin-C in Canine Mammary Carcinomas2014
- Author(s)
  Yosnimura H, Micnisnita M, Ohkusu-Tsukada K, Matsuda Y, Ishiwata T, Naito Z, Takahashi K.
- Journal Title
  
  Veterinary Pathology
  
  Volume: Published online first Issue: 1 Pages: 92-96
- DOI
  10.1177/0300985814522817
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J11084, KAKENHI-PROJECT-26292161, KAKENHI-PROJECT-26870622, KAKENHI-PROJECT-26450434
[Journal Article] Nestin delineates pancreatic cancer stem cells in metastatic foci of NOD/Shi-scid IL2Rγ(null) (NOG) mice2014
- Author(s)
  Matsuda Y, Yoshimura H, Ueda J, Naito Z, Korc M, Ishiwata T
- Journal Title
  
  Am J Pathol
  
  Volume: 184(3) Issue: 3 Pages: 674-85
- DOI
  10.1016/j.ajpath.2013.11.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590477, KAKENHI-PROJECT-25462127
[Journal Article] Nestin regulates proliferation, migration, invasion and stemness of lung adenocarcinoma2014
- Author(s)
  Narita K, Matsuda Y, Seike M, Naito Z, Gemma A, Ishiwata T
- Journal Title
  
  Int J Oncol
  
  Volume: 44(4) Issue: 4 Pages: 1118-30
- DOI
  10.3892/ijo.2014.2278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590477, KAKENHI-PROJECT-25461172, KAKENHI-PROJECT-25462127
[Journal Article] Simultaneous Detection of Different RNAs Using a Novel Branched DNA <i>in situ</i> Hybridization Method2014
- Author(s)
  Yoshimura H, Matsuda Y, Kawamoto Y, Naito Z, Ishiwata T.
- Journal Title
  
  Journal of Nippon Medical School
  
  Volume: 81 Issue: 2 Pages: 62-63
- DOI
  10.1272/jnms.81.62
- NAID
  130004147290
- ISSN
  1345-4676, 1347-3409
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J11084, KAKENHI-PROJECT-23590477, KAKENHI-PROJECT-26870622
[Journal Article] Nestin delineates pancreatic cancer stem cells in metastatic foci of NOD/Shi-scid IL2Rγ(null) (NOG) mice2014
- Author(s)
  Matsuda Y, Yoshimura H, Ueda J, Naito Z, Korc M and Ishiwata T
- Journal Title
  
  Ａｍｅｒｉｃａｎ　Ｊｏｕｒｎａｌ　ｏｆ　Ｐａｔｈｏｌｏｇｙ
  
  Volume: 184 Pages: 674-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461027
[Journal Article] Nestin is highly expressed in advanced-stage melanomas and neurotized nevi2013
- Author(s)
  Akiyama M, Matsuda Y, Ishiwata T, Naito Z, Kawana S
- Journal Title
  
  Oncol Rep
  
  Volume: 29 Issue: 4 Pages: 1595-9
- DOI
  10.3892/or.2013.2287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689038, KAKENHI-PROJECT-23590477, KAKENHI-PROJECT-23650604, KAKENHI-PROJECT-25462127
[Journal Article] Inhibition of the stem cell marker nestin reduces tumor growth and invasion of malignant melanoma2013
- Author(s)
  Akiyama M, Matsuda Y, Ishiwata T, Naito Z, Kawana S
- Journal Title
  
  J Invest Dermatol
  
  Volume: 133 Issue: 5 Pages: 1384-7
- DOI
  10.1038/jid.2012.508
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689038, KAKENHI-PROJECT-23590477, KAKENHI-PROJECT-23650604
[Journal Article] Phosphorylation of Thr(1495) of nestin in a mouse model of cerebral ischemia and reperfusion damage2013
- Author(s)
  Matsuda Y, Suzuki G, Kusano T, Kawamoto Y, Yoshimura H, Fuse A, Yokota H, Naito Zand Ishiwata T
- Journal Title
  
  Ｐａｔｈｏｌｏｇｙ　Ｉｎｔｅｒｎａｔｉｏｎａｌ
  
  Volume: 63 Issue: 9 Pages: 448-56
- DOI
  10.1111/pin.12092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461027, KAKENHI-PROJECT-25462127
[Journal Article] Expression, roles, and potential as a novel molecular target for colorectal cancer.2013
- Author(s)
  Matsuda Y, Ueda J, Ishiwata T.
- Journal Title
  
  Patholog Res Int.
  
  Volume: 未定 Pages: 574768-574768
- DOI
  10.1155/2012/574768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531, KAKENHI-PROJECT-22689038, KAKENHI-PROJECT-23650604
[Journal Article] Expression of Lumican in Hidroacanthoma Simplex and Clonal-Type Seborrheic Keratosis as a Potent Differential Diagnostic Marker2013
- Author(s)
  Takayama R, Ansai SI, Ishiwata T, Yamamoto T, Matsuda Y, Naito Z, Kawana S
- Journal Title
  
  Am J Dermatopathol
  
  Volume: (Epub ahead of print) Issue: 8 Pages: 655-660
- DOI
  10.1097/dad.0b013e31828b6bbf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590477
[Journal Article] Nestin regulates epithelial-mesenchymal transitionmarker expression in pancreatic ductal adenocarcinoma cell lines.2013
- Author(s)
  Hagio M, Matsuda Y, Suzuki T, Ishiwata T
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 1 Pages: 83-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Fibroblast Growth Factor Receptor2 IIIc as a Therapeutic Target for Colorectal Cancer Cells.2012
- Author(s)
  Matsuda Y, Hagio M, Seya T, IshiwataT
- Journal Title
  
  Molecular Cancer Therapeutics.
  
  Volume: 11(9) Pages: 2010-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Secreted 70 kiloDalton lumican stimulates growthand inhibits invasion of human pancreatic cancer.2012
- Author(s)
  Yamamoto T, Matsuda Y, Kawahara K, Ishiwata T, Naito Z
- Journal Title
  
  Cancer Letters
  
  Volume: 320(1) Pages: 31-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Keratinocyte growth factor induces matrix metalloproteinase-9 expression and correlates with venous invasion in pancreatic cancer.2012
- Author(s)
  Cho K, Matsuda Y, Ueda J, Uchida E, Naito Z, Ishiwata T
- Journal Title
  
  Int J Oncol
  
  Volume: 40(4) Pages: 1040-1048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Keratinocyte growth factor induces matrix metalloproteinase-9 expression and correlates with venous invasion in pancreatic cancer2012
- Author(s)
  Cho K, Matsuda Y, Ueda J, Uchida E, Naito Z, Ishiwata T
- Journal Title
  
  Int J Oncol
  
  Volume: 40(4) Issue: 4 Pages: 1040-8
- DOI
  10.3892/ijo.2011.1280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590477
[Journal Article] Secreted 70kDa lumican stimulates growth and inhibits invasion of human pancreatic cancer2012
- Author(s)
  T. Yamamoto, Y. Matsuda, K. Kawahara, T. Ishiwata, Z. Naito
- Journal Title
  
  Cancer letters
  
  Volume: 320巻 Issue: 1 Pages: 31-39
- DOI
  10.1016/j.canlet.2012.01.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790675, KAKENHI-PROJECT-23590477
[Journal Article] Keratinocyte growth factor stimulates growth of MIA PaCa-2 cells through extracellular signal-regulated kinase phosphorylation.2012
- Author(s)
  Yamamoto T, Matsuda Y, Kawahara K, Naito Z, Ishiwata T.
- Journal Title
  
  Oncol Lett.
  
  Volume: 3 Pages: 307-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Enhanced expression of fibroblast growth factor receptor 2 IIIc promotes human pancreatic cancer cell proliferation2012
- Author(s)
  Ishiwata T, Matsuda Y, Yamamoto T, Uchida E, Korc M, Naito Z
- Journal Title
  
  Am J Pathol
  
  Volume: 180 Issue: 5 Pages: 1928-41
- DOI
  10.1016/j.ajpath.2012.01.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689038, KAKENHI-PROJECT-23590477
[Journal Article] Enhanced expression of fibroblast growth factor receptor 2 IIIc promotes human pancreatic cancer cell proliferation.2012
- Author(s)
  Ishiwata T, Matsuda Y, Yamamoto T, Uchida E, Korc M, Naito Z
- Journal Title
  
  Am J Pathol
  
  Volume: 180(5) Pages: 1928-1941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Nestin as a novel therapeutic target for pancreatic cancer via tumor angiogenesis2012
- Author(s)
  Yamahatsu K, Matsuda Y, Ishiwata T, Uchida E, Naito Z
- Journal Title
  
  Int J Oncol
  
  Volume: 40(5) Pages: 1345-1357
- NAID
  40019700383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Keratinocyte growth factor stimulates growth of MIA PaCa-2 cells through ERK phosphorylation.2012
- Author(s)
  Yamamoto T, Mastuda Y, Kawahara K, Naito Z, Ishiwata T
- Journal Title
  
  Oncology Letters
  
  Volume: 3(2) Pages: 307-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Fibroblast growth factor receptor 2 IIIc as a therapeutic target for colorectal cancer cells.2012
- Author(s)
  Matsuda Y, Hagio M, Seya T, Ishiwata T.
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: 11 Issue: 9 Pages: 2010-20
- DOI
  10.1158/1535-7163.mct-12-0243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531, KAKENHI-PROJECT-22689038, KAKENHI-PROJECT-23650604
[Journal Article] Ultra-high-resolution Images of Nestin and Vimentin in Pancreatic Carcinoma Cells Using 2 Novel Microscopy Systems2012
- Author(s)
  Yoshimura H, Matsuda Y, Naito Z, Murase M, Kawamoto Y, Ishiwata T
- Journal Title
  
  Journal of Nippon Medical School
  
  Volume: 79 Issue: 6 Pages: 392-393
- DOI
  10.1272/jnms.79.392
- NAID
  130004057396
- ISSN
  1345-4676, 1347-3409
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590477
[Journal Article] Expression of cancer stem cell markers in pancreatic intraepithelial neoplasias and pancreatic ductal adenocarcinomas.2012
- Author(s)
  Kure S, Matsuda Y, Hagio M, Ueda J, Naito Z, Ishiwata T.
- Journal Title
  
  Int J Oncol.
  
  Volume: 23 Issue: 4 Pages: 1314-1324
- DOI
  10.3892/ijo.2012.1565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531, KAKENHI-PROJECT-22689038, KAKENHI-PROJECT-23590477, KAKENHI-PROJECT-23650604
[Journal Article] Nestin as a novel therapeutic target for pancreatic cancer via tumor angiogenesis2012
- Author(s)
  Yamahatsu K, Matsuda Y, Ishiwata T, Uchida E, Naito Z
- Journal Title
  
  Int J Oncol
  
  Volume: 40 Pages: 1345-57
- DOI
  10.3892/ijo.2012.1333
- NAID
  40019700383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689038, KAKENHI-PROJECT-23590477
[Journal Article] Keratinocyte growth factor stimulates growth of MIA PaCa-2 cells through extracellular signal-regulataed kinase phosphorylation2012
- Author(s)
  T. Yamamoto, Y. Matsuda, K. Kawahara, Z. Naito, T. Ishiwata
- Journal Title
  
  Oncology letters
  
  Volume: 3巻 Issue: 2 Pages: 307-310
- DOI
  10.3892/ol.2011.466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790675, KAKENHI-PROJECT-23590477
[Journal Article] Expression and role of nestin in human cervical intraepithelial neoplasia and cervical cancer2012
- Author(s)
  Sato A, Ishiwata T, Matsuda Y, Yamamoto T, Asakura H, Takeshita T, Naito Z
- Journal Title
  
  Int J Oncol
  
  Volume: 41(2) Issue: 2 Pages: 441-8
- DOI
  10.3892/ijo.2012.1473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590477
[Journal Article] CD44 in human glioma correlates with histopathological grade and cell migration2012
- Author(s)
  Yoshida T, Matsuda Y, Naito Z, Ishiwata T
- Journal Title
  
  Pathol Int
  
  Volume: 62(7) Issue: 7 Pages: 463-70
- DOI
  10.1111/j.1440-1827.2012.02823.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590477
[Journal Article] Expression ofCancer Stem Cell Markers in Pancreatic Intraepithelial Neoplasias and Pancreatic Ductal Adenocarcinomas.2012
- Author(s)
  Kure S, Matsuda Y, Hagio M, Ueda J, Naito Z, Ishiwata T
- Journal Title
  
  Int J Oncol.
  
  Volume: 41 Pages: 1314-1324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Keratinocyte growth factor induces matrix metalloprotemase-9 expression and correlates with venous invasion in pancreatic cancer2012
- Author(s)
  Cho K, Matsuda Y, Ueda J, Uchida E, Naito Z, Ishiwata T
- Journal Title
  
  Int J Oncol
  
  Volume: 40 Pages: 1040-1048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Immunocytochemical analysis of a three-dimensional spheroidal culture system2011
- Author(s)
  Matsuda Y, Ishiwata T, Naito Z
- Journal Title
  
  J Nippon Med Sch
  
  Volume: 78(4) Pages: 206-7
- NAID
  130004147095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590477
[Journal Article] Nestin is a novel target for suppressing pancreatic cancer cell migration, invasion and metastasis.2011
- Author(s)
  Matsuda Y, Naito Z, Kawahara K, Nakazawa N, Korc M, Ishiwata T.
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 11 Pages: 512-523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Nestin is a novel target for suppressing pancreatic cancer cell migration, invasion and metastasis.2011
- Author(s)
  Matsuda Y, Naito Z, Kawahara K, Nakazawa N, Korc M, Ishiwata T
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 11(5) Pages: 512-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Neuroepithelial stem cell marker nestin regulates the migration, invasion and growth of human gliomas.2011
- Author(s)
  Ishiwatao T, Teduka K, Yamamoto T, Kawahara K, Matsuda Y, Naito Z
- Journal Title
  
  Oncology Reports
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Comparison of Fixation Methods for Preservation of Morphology, RNAs, and Proteins From Paraffin-embedded Human Cancer Cell-implanted Mouse Models.2011
- Author(s)
  Matsuda Y, Fujii T, Suzuki T, Yamahatsu K, Kawahara K, Teduka K, Kawamoto Y, Yamamoto T, Ishiwata T, Naito Z.
- Journal Title
  
  J Histochem Cytochem.
  
  Volume: 59 Pages: 68-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Overexpressed fibroblast growth factor receptor 2 in the invasive front of colorectal cancer as a potential therapeutic target of colorectal cancer2011
- Author(s)
  Mastuda Y, Ishiwata T, Yamahatsu K, Kawahara K, Hagio M, Peng WX, Yamamoto T, Nakazawa N, Seya T, Ohaki Y, Naito Z.
- Journal Title
  
  Cancer Letters
  
  Volume: 309 Issue: 2 Pages: 209-19
- DOI
  10.1016/j.canlet.2011.06.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791552, KAKENHI-PROJECT-23590477
[Journal Article] Overexpressed fibroblast growth factor receptor 2 in the invasive front of colorectal cancer as a potential therapeutic target of colorectal cancer.2011
- Author(s)
  Mastuda Y, Ishiwata T, Yamahatsu K, Kawahara K, Hagio M, Peng W-X, Yamamoto T, Nakazawa N, Seya T, Ohaki Y, Naito Z
- Journal Title
  
  Cancer Letters
  
  Volume: 309(2) Pages: 209-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Keratinocyte growth factor induces vascular endothelial growth factor-A expression in colorectal cancer cells2009
- Author(s)
  Narita K, Fujii T, Ishiwata T, Yamamoto T, Kawamoto Y, Kawahara K, Nakazawa N, Naito Z
- Journal Title
  
  Int J Oncol. 34
  
  Pages: 355-60
- Data Source
  KAKENHI-PROJECT-19591603
[Journal Article] Expression of keratinocyte growth factor and its receptor in human endometrial cancer in cooperation with steroid hormones2008
- Author(s)
  Ishikawa A, Kudo M, Nakazawa N, Onda M, Ishiwata T, Takeshita T, Naito Z
- Journal Title
  
  Int J Oncol 32
  
  Pages: 565-574
- Data Source
  KAKENHI-PROJECT-19591603
[Journal Article] Role of lumican in cancer and adjacent stromal tissues in human pancreatic cancer2007
- Author(s)
  Toshiyuki Ishiwata
- Journal Title
  
  Oncology Reports 18
  
  Pages: 537-543
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591526
[Journal Article] Role of lumican in cancer cells and adjacent stromal tissues in human pancreatic cancer2007
- Author(s)
  Toshiyuki, Ishiwata
- Journal Title
  
  Oncology Reports 18-3
  
  Pages: 537-543
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591526
[Journal Article] Role of lumican in cancer cells and adjacent stromal tissues in human pancreatic cancer2007
- Author(s)
  Toshiyuki Ishiwata
- Journal Title
  
  Oncology Reports 18
  
  Pages: 537-543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591526
[Journal Article] Defined localization of nestin-expressing cells in L-arginine-induced acute pancreatitis.2006
- Author(s)
  Toshiyuki Ishiwata
- Journal Title
  
  Pancreas 32
  
  Pages: 360-368
- NAID
  10024366118
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591365
[Journal Article] Defined localization of nestin-expressing cells in L-arginine-induced acute pancreatitis.2006
- Author(s)
  Toshiyuki Ishiwata
- Journal Title
  
  Pancreas. 32
  
  Pages: 360-368
- NAID
  10024366118
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591365
[Journal Article] Effect of morpholino antisense oligonucleotide against lumican mRNA in human embryonic kidney (HEK) 293 cells2004
- Author(s)
  Toshiyuki Ishiwata
- Journal Title
  
  Pathology International 52・2
  
  Pages: 77-81
- NAID
  10012711061
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591449
[Journal Article] Effect of morpholino antisense oligonucleotide against lumican mRNA in human embryonic kidney (HEK) 293 cells2004
- Author(s)
  Toshiyuki IShiwata
- Journal Title
  
  Pathology International 52・2
  
  Pages: 77-81
- NAID
  10012711061
- Data Source
  KAKENHI-PROJECT-15591449
[Journal Article] Effect of morpholino antisense oligonucleotide against lumican mRNA in human embryonic kidney(HEK) 293 cells2004
- Author(s)
  Toshiyuki Ishiwata
- Journal Title
  
  Pathology International 52-2
  
  Pages: 77-81
- NAID
  10012711061
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591449
[Journal Article] Role of lumican in cancer cells and adjacent stromal tissues in human pancreatic cancer.
- Author(s)
  Toshiyuki Ishiwata
- Journal Title
  
  Oncology Reports (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591445
[Journal Article] Clinicopathological Features of Thirty Autopsy Cases of Pancreatic Carcinoma
- Author(s)
  Matsuda Y, Hagio M, Naito Z, Ishiwata T
- Journal Title
  
  J Nippon Med Sch
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Enhanced expression of fibroblast growth factor receptor 2 IIIc promotes human pancreatic cancer cell proliferation
- Author(s)
  Ishiwata T, Matsuda Y, Yamamoto T, Uchida E, Korc M, Naito Z
- Journal Title
  
  Am J Pathol
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Nestin and other putative cancer stem cell markers in pancreatic cancer
- Author(s)
  Matsuda Y, Kure S, Ishiwata T
- Journal Title
  
  Med Mol Morphol
  
  Volume: (In press)
- NAID
  10030831949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Secreted 70 kDa lumican stimulates growth and inhibits invasion of human pancreatic cancer
- Author(s)
  Yamamoto T, Matsuda Y, Kawahara K, Ishiwata T, Naito Z
- Journal Title
  
  Cancer Letters
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591531
[Journal Article] Role of lumican in cancer cells and adjacent stromal tissues in human pancreatic cancer.
- Author(s)
  Toshiyuki Ishiwata
- Journal Title
  
  Oncology Reports (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591445
[Presentation] 個別化治療を目指した、膵がんの幹細胞と多様性の研究2024
- Author(s)
  石渡俊行
- Organizer
  金沢大学がん進展制御研究所第4回腫瘍制御共同研究セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22K08882
[Presentation] Age-related increase of proportion of microsatellite instability in gastric, colorectal, and endometrial carcinomas2023
- Author(s)
  Arai Tomio、Komatsu Akiko、Nagasaka Takuya、Nonaka Keisuke、Ishiwata Toshiyuki
- Organizer
  International Academy of Geriatrics and Gerontology (IAGG) Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06972
[Presentation] 早期胃型腫瘍から粘液癌への進展についての病理学的検討2023
- Author(s)
  六反啓文、新井冨生、石渡俊行、牛久哲男
- Organizer
  第34回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-22K06972
[Presentation] 膵癌培養細胞株におけるスフェアの形成過程および接着遊走過程のタイムラプス解析2023
- Author(s)
  志智優樹、五味不二也、長谷川康子、進士誠一、高橋公正、石渡俊行
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K08882
[Presentation] Enhanced morphofunctional characteristics of pancreatic ductal adenocarcinoma cell lines in three-dimensional culture.2023
- Author(s)
  Shichi Yuuki、Gomi Fujiya、Hasegawa Yasuko、Nonaka Keisuke、Shinji Seiichi、Takahashi Kimimasa、Ishiwata Toshiyuki
- Organizer
  Second JCA/AACR Precision Cancer Medicine International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08882
[Presentation] FGFR4 阻害剤 BLU554 は膵癌細胞の増殖、浸潤を抑制し細胞老化を誘導する.2023
- Author(s)
  五味不二也、志智優樹、進士誠一、石渡俊行.
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08764
[Presentation] Enhanced morphofunctional characteristics of pancreatic ductal adenocarcinoma cell lines in three-dimensional culture.2023
- Author(s)
  Yuuki Shichi, Fujiya Gomi, Yasuko Hasegawa, Seiichi Shinji, Kimimasa Takahashi, Toshiyuki Ishiwata.
- Organizer
  Second JCA/AACR Precision Cancer Medicine International Conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08764
[Presentation] 膵癌培養細胞株におけるスフェアの形成過程および接着遊走過程のタイムラプス解析2023
- Author(s)
  志智優樹, 五味不二也, 長谷川康子, 進士誠一, 高橋公正, 石渡俊行
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] Enhanced Morphofunctional Characteristics of Pancreatic Ductal Adenocarcinoma Cell Lines in Three-Dimensional Cultures2023
- Author(s)
  Yuuki Shichi, Fujiya Gomi, Yasuko Hasegawa, Seiichi Shinji, Kimimasa Takahashi, Toshiyuki Ishiwata
- Organizer
  The 2nd JCA-AACR Precision Cancer Medicine International Conference
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 膵癌培養細胞株におけるスフェアの形成過程および接着遊走過程のタイムラプス解析.2023
- Author(s)
  志智優樹、五味不二也、長谷川康子、進士誠一、高橋公正、石渡俊行.
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08764
[Presentation] FGFR4 inhibitors reduced cell proliferation and migration, and induced cellular senescence in pancreatic cancer.2023
- Author(s)
  Toshiyuki Ishiwata, Norihiko Sasaki, Fujiya Gomi, Yuuki Shichi, Seiichi Shinji, Masashi Toyoda.
- Organizer
  AGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08764
[Presentation] 3次元培養による膵がん培養細胞株の上皮間葉系形質とムチン産生能の比較検討2022
- Author(s)
  志智優樹, 五味不二也, 野中敬介, 石渡俊行
- Organizer
  第18回日本病理学会カンファレンス
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 膵がん培養細胞株の老化誘導と老化細胞除去療法2022
- Author(s)
  五味不二也, 佐々木紀彦, 志智優樹, 野中敬介, 石渡俊行
- Organizer
  TOBIRA第10回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] Gp130/STAT3シグナル伝達は、長鎖ノンコーディングRNAのH19の発現を含む膵臓癌幹細胞の機能を調節する2022
- Author(s)
  佐々木紀彦, 平野和己, 志智優樹, 五味不二也, 吉村久志, 松下晃, 板倉陽子, 豊田雅士, 石渡俊行
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 膵がんの上皮間葉系性質と糖鎖発現の多様性2022
- Author(s)
  志智優樹, 佐々木紀彦, 五味不二也, 野中敬介, 石渡俊行
- Organizer
  TOBIRA第10回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 3次元培養による膵癌培養細胞の上皮間葉系形質と粘液産生能の比較検討2022
- Author(s)
  志智優樹, 長谷川康子, 佐々木紀彦, 五味不二也, 野中敬介, 吉村久志, 高橋公正, 豊田雅士, 新井冨生, 石渡俊行
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 3次元培養による膵癌細胞株の上皮間葉系形質の増強2022
- Author(s)
  石渡俊行, 志智優樹, 五味不二也, 野中敬介, 佐々木紀彦, 豊田雅士, 高橋公正, 新井冨生
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] FGFR4阻害剤BLU554の膵癌細胞株に対する効果2022
- Author(s)
  五味不二也, 佐々木紀彦, 志智優樹, 野中敬介, 豊田雅士, 石渡俊行
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 3次元培養による膵癌培養細胞の形態学的特徴と粘液産生能の比較検討2022
- Author(s)
  志智優樹, 五味不二也, 野中敬介, 高橋公正, 新井冨生, 石渡俊行
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 2次元培養と3次元培養による膵癌培養細胞株の形態・機能変化と薬剤感受性の検討2021
- Author(s)
  石渡俊行, 南風花, 佐々木紀彦, 志智優樹, 五味不二也, 道下正貴, 豊田雅士
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] 3次元培養による膵癌培養細胞株の形態および機能的特徴と薬剤感受性の検討2021
- Author(s)
  志智優樹, 南風花, 佐々木紀彦, 五味不二也, 道下正貴, 塚田晃三, 豊田雅士, 高橋公正, 石渡俊行
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08744
[Presentation] Metabolites profiling in spheres derived from canine mammary carcinoma using gas chromatography mass spectrometry2017
- Author(s)
  Masaki Michishita, Namika Saito, Satoshi Nozawa, Rina Furumoto, Takayuki Nakagawa, Touko Sato, Kinya Katayama, Hiroyuki Tazaki, Toshiyuki Ishiwata, Kimimasa Takahashi
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26292161
[Presentation] 犬乳癌幹細胞の脂肪酸代謝プロファイル解析2017
- Author(s)
  古本莉奈、道下正貴、齋藤那美香、野澤聡司、中川貴之、佐藤稲子、片山欣哉、田崎弘之、石渡俊行、髙橋公正
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-26292161
[Presentation] 犬の萎縮精巣および潜在精巣におけるセルトリ細胞の未成熟マーカー発現の比較2017
- Author(s)
  佐々木　悠、吉村久志、道下正貴、塚田晃三、石渡俊行、高橋公正
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-26292161
[Presentation] Fibroblast growth factor receptor-4 (FGFR-4) as a novel therapeutic target for pancreatic cancer2016
- Author(s)
  Toshiyuki Ishiwata, Hisashi Yoshimura, Yoko Matsuda, Tomio Arai, Naoshi Ishikawa, Junko Aida, Kaiyo Takubo, Shunji Ishiwata
- Organizer
  American Association for Cancer Research Annual Meeting 2016
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2016-04-16
- Data Source
  KAKENHI-PROJECT-16K10613
[Presentation] Occult and clinical pancreatic cancers in elderly patients.2015
- Author(s)
  Matsuda Y, Suzuki A, Hamashima Y, Hamayasu H, Yoshimura H, Ishiwata T, Arai T.
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  フィラデルフィア、米国
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462127
[Presentation] 癌幹細胞と上皮間葉転換を標的とした革新的な癌治療法2015
- Author(s)
  石渡　俊行
- Organizer
  第６１回日本病理学会秋期特別総会
- Place of Presentation
  東京大学安田講堂（東京都文京区）
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-25461027
[Presentation] 膵癌におけるFGFR-2の抑制効果と、発現制御機構の検討2013
- Author(s)
  石渡俊行、松田陽子、吉村久志、川原清子、河本陽子、鈴木妙子、柳澤祐次、内田英二、内藤善哉
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] 術前化学療法施行膵癌症例における病理学的変化の検討2013
- Author(s)
  吉村久志 , 松田陽子, 川原清子, 河本陽子, 村瀬めぐみ, 松下晃, 内田英二, 土屋眞一, 石渡俊行, 内藤善哉
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] Inhibition of Phosphorylation of Nestin Decrease Pancreatic Cancer Cell Growth2013
- Author(s)
  Matsuda Y, Yoshimura H, Suzuki T, Naito Z, Kawahara K, Yanagisawa Y, Kawamoto Y, Ishiwata T
- Organizer
  American association for cancer research, 104th annual meeting 2013, AACR
- Place of Presentation
  Washington, DC
- Year and Date
  2013-04-09
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] 膵癌の新たな治療標的としてのリン酸化nestin.2013
- Author(s)
  2. 松田陽子, 吉村久志, 内藤善哉, 鈴木妙子, 河本陽子, 川原清子, 石渡俊行
- Organizer
  第72回日本癌学会学術総会.
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-25462127
[Presentation] 膵癌における線維芽細胞増殖因子受容体（FGFR-2）発現制御機構と治療応用の検討2013
- Author(s)
  石渡俊行、松田陽子、吉村久志、河本陽子、鈴木妙子、松下晃、中村慶春、内田英二、内藤善哉
- Organizer
  第44回日本膵臓学会大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] Inhibition of Nestin Using siRNA as a Novel Therapeutic Option for Pancreatic Cancer2013
- Author(s)
  Ishiwata T, Yoshimura H, Suzuki T, Yanagisawa Y, Kawamoto Y, Kawahara K, Naito Z, Korc M, Matsuda Y
- Organizer
  American association for cancer research, 104th annual meeting 2013, AACR
- Place of Presentation
  Washington, DC
- Year and Date
  2013-04-07
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] 膵癌およびPanINにおけるnestinの発現と、分子標的としての有用性2013
- Author(s)
  松田陽子、吉村久志、上田純志、川原清子、鈴木妙子、柳澤祐次、松下晃、内田英二、内藤善哉、石渡俊行
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] 膵癌におけるFGFR-2の抑制効果と、発現制御機構の検討2013
- Author(s)
  石渡俊行, 松田陽子, 吉村久志, 川原清子, 河本陽子, 鈴木妙子, 柳澤祐次, 内田英二, 内藤善哉
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] ネスチンに対するsiRNA による膵癌増殖と転移の抑制効果の研究2013
- Author(s)
  石渡俊行、吉村久志、内藤善哉、鈴木妙子、河本陽子、川原清子、松下晃、中村慶春、内田英二、松田陽子
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] 手術検体からの膵癌培養細胞樹立の検討2013
- Author(s)
  川原清子、松田陽子、中澤南堂、河本陽子、鈴木妙子、石渡俊行、内田英二、内藤善哉
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] 長鎖non-coding RNA H19の膵癌における発現とその意義についての検討2013
- Author(s)
  吉村久志、松田陽子、村瀬めぐみ、川原清子、松下晃、中村慶春、内田英二、内藤善哉、石渡俊行
- Organizer
  第44回日本膵臓学会大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] 膵癌の新たな治療標的としてのリン酸化nestin2013
- Author(s)
  松田陽子、吉村久志、内藤善哉、鈴木妙子、河本陽子、川原清子、石渡俊行
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] 膵癌における術前化学療法の影響の検討2013
- Author(s)
  松田陽子、石渡俊行、吉村久志、渡會泰彦、川原清子、河本陽子、松下晃、内田英二、土屋眞一、内藤善哉
- Organizer
  第54回日本臨床細胞学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] Inhibition of Phosphorylation of Nestin Decrease Pancreatic Cancer Cell Growth2013
- Author(s)
  Matsuda Y, Yoshimura H, Suzuki T, Naito Z, Kawahara K, Yanagisawa Y, Kawamoto Y, Ishiwata T
- Organizer
  American association for cancer research, 104th annual meeting
- Place of Presentation
  Washington,DC USA
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] 手術検体からの膵癌培養細胞樹立の検討2013
- Author(s)
  川原清子、松田陽子、中澤南堂、河本陽子、鈴木妙子、石渡俊行、内田英二、内藤善哉
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] Inhibition of Nestin Using siRNA as a Novel Therapeutic Option for Pancreatic Cancer2013
- Author(s)
  Ishiwata T, Yoshimura H, Suzuki T, Yanagisawa Y, Kawamoto Y, Kawahara K, Naito Z, Korc M, Matsuda Y
- Organizer
  American association for cancer research, 104th annual meeting
- Place of Presentation
  Washington,DC USA
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] Molecular therapeutic targets for gastrointestinal cancer: Fibroblast growth factor receptor 2.2012
- Author(s)
  Ishiwata T
- Organizer
  18th International Heidelberger Symposium on Cancer Research
- Place of Presentation
  Ulm, Germany
- Invited
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] 膵癌細胞における分泌型lumicanの増殖・浸潤への関与2012
- Author(s)
  山本哲志、工藤光洋、川原清子、彭為霞、松田陽子、石渡俊行、内藤善哉
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] Molecular therapeutic targets for gastrointestinal cancer: Fibroblast growth factor receptor 2.2012
- Author(s)
  Ishiwata T
- Organizer
  第18回国際チャールズハイデルベルガー癌研究シンポジウム、ドイツ (18th International Heidelberger Symposium on Cancer Research).
- Place of Presentation
  ドイツ
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] 浸潤性膵癌におけるESRP1の発現と転移および予後との関連の検討2012
- Author(s)
  上田純志、松田陽子、内田英二、山初和也、内藤善哉、石渡俊行
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] Expression of Cancer Stem Cell Markers in Pancreatic Ductal Adenocarcinomas and Pancreatic Intraepithelial Neoplasias2012
- Author(s)
  Kure S, Matsuda Y, Hagio M, Suzuki T, Ueda J, Yamahatsu K, Yamamoto T, Ishiwata T, Naito Z
- Organizer
  American association for cancer research, 103rd annual meeting 2012, AACR
- Place of Presentation
  Chicago, IL
- Year and Date
  2012-04-01
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] 膵癌・PanINにおける癌幹細胞マーカーの発現2012
- Author(s)
  呉壮香、松田陽子、萩尾真人、鈴木妙子、柳沢祐次、上田純志、山初和也、山本哲志、内藤善哉、石渡俊行
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] 膵癌・PanIN における癌幹細胞マーカーの発現2012
- Author(s)
  呉　壮香, 松田陽子, 萩尾真人, 鈴木妙子, 柳澤祐次, 上田純志, 山初和也, 山本哲志, 内藤善哉, 石渡俊行
- Organizer
  日本病理学会（第101回）
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] Expression of Cancer Stem Cell Markers in Pancreatic Ductal Adenocarcinomas and Pancreatic Intraepithelial Neoplasias.2012
- Author(s)
  S Kure, Y Matsuda, M Hagio, T Suzuki, J Ueda, K Yamahastu, T Yamamoto, T Ishiwata, Z Naito
- Organizer
  American association for cancer research (103rd annual meeting 2012)
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] 浸潤性膵管癌組織におけるESRP1 とFGFR2 の発現と役割の検討2012
- Author(s)
  上田純志、松田陽子、山初和也、内田英二、内藤善哉、石渡俊行
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] Inhibitory effects of fibroblast growth factor receptor 2 in pancreatic cancer.2012
- Author(s)
  Ishiwata T, Yoshimura H, Naito Z, Uchida E, Korc M, Matsuda Y
- Organizer
  Pancreas Cancer 2012 in Kyoto
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] Fibroblast growth factor receptor-2 IIIc as a novel therapeutic target for pancreatic cancer.2012
- Author(s)
  Ishiwata T
- Organizer
  2nd Yonsei-Nippon Medical School Pancreatic Tumor Study Group Joint Meeting
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] Inhibitory Effects of Fibroblast Growth Factor Receptor 2 in Pancreatic Cancer.2012
- Author(s)
  Ishiwata T
- Organizer
  Pancreas Cancer2012 in Kyoto / 国際膵癌シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] Fibroblast Growth Factor Receptor-2 IIIc as a Novel Therapeutic Target for Pancreatic Cancer.2012
- Author(s)
  Ishiwata T
- Organizer
  第2回延世(ヨンセイ)大学・日本医科大学合同膵癌研究会.
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] NOGマウス膵癌転移モデルの転移細胞株における細胞動態の検討2011
- Author(s)
  川原清子、松田陽子、藤井雄文、山初和也、上田純志、石渡俊行、内藤善哉
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] 膵癌の新規分子標的としての線維芽細胞増殖因子受容体 2(FGFR-2)2011
- Author(s)
  石渡俊行
- Organizer
  第70回日本癌学会学術総会.
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] 膵癌の新規分子標的としての線維芽細胞増殖因子受容体2(FGFR2)2011
- Author(s)
  石渡俊行, 他7名
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] 線維芽細胞増殖因子受容体(FGFR2)を標的とした膵癌治療の研究2011
- Author(s)
  石渡俊行, 他8名
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Year and Date
  2011-04-28
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] 線維芽細胞増殖因子受容体(FGFR-2)を標的とした膵癌治療の研究2011
- Author(s)
  石渡俊行
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] Fibroblast growth factor receptor 2 as a novel therapeutic target for cancer cell growth and angiogenesis in human pancreatic cancer2011
- Author(s)
  Toshiyuki Ishiwata, et al
- Organizer
  102th AACR
- Place of Presentation
  Orlando, Florida, USA
- Year and Date
  2011-04-04
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] Fibroblast growth factor receptor 2 as a novel therapeutic target for cancer cell growth and angiogenesis in human pancreatic cancer2011
- Author(s)
  Ishiwata T
- Organizer
  第102回米国癌学会 (American association for cancer research,102th annual meeting)
- Place of Presentation
  フロリダ
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] 膵癌の新規分子標的としての線維芽細胞増殖因子受容体2(FGFR2)2011
- Author(s)
  石渡俊行、松田陽子、上田純志、川原清子、萩尾真人、山本哲志、内田英二、Murray Korc、内藤善哉
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590477
[Presentation] 線維芽細胞増殖因子受容体(FGFR2 IIIc)を標的とした膵癌治療法の研究2010
- Author(s)
  石渡俊行、松田陽子、山本哲志、河本陽子、川原清子、恩田宗彦、内田英二、内藤善哉
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  京王プラザ(東京)
- Year and Date
  2010-04-29
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] 線維芽細胞増殖因子受容体(FGFR-2IIIc)を標的とした膵癌治療法の研究2010
- Author(s)
  石渡俊行
- Organizer
  第99回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] Fibroblast growth factor receptor (FGFR) 2 IIIc, is a novel molecular target for suppressing pancreatic cancer cell growth and migration2010
- Author(s)
  Ishiwata T, Matsuda Y, Kawahara K, Yamamoto T, Teduka K, Uchida E, Korc M, Naito Z
- Organizer
  American Association for Cancer Research, 101th annual meeting 2010
- Place of Presentation
  ワシントンDC(米国)
- Year and Date
  2010-04-20
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] Fibroblast growth factor receptor 2 as a novel therepeutic target for pancreatic cancer2010
- Author(s)
  Ishiwata T
- Organizer
  第56回日本病理学会秋期特別総会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] Fibroblast growth factor receptor (FGFR) 2 IIIc, is a novel molecular target for suppressing pancreatic cancer cell growth and migration2010
- Author(s)
  Ishiwata T
- Organizer
  第01回米国癌学会(American association for cancer research, 101th annual meeting 2010)
- Place of Presentation
  ワシントン DC
- Data Source
  KAKENHI-PROJECT-22591531
[Presentation] Fibroblast growth factor receptor 2 as a novel therepeutic target for pancreatic cancer.2010
- Author(s)
  Ishiwata T, Yoko M, Kawahara K, Yamamoto T, Teduka K, Uchida E, Korc M, Naito Z
- Organizer
  第56回日本病理学会秋期特別総会
- Place of Presentation
  北九州国際会議場(福岡)
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-22591531

1. NAITO Zenya (20237184)

# of Collaborated Projects: 11 results

# of Collaborated Products: 54 results
2. SHINJI SEIICHI (80409193)

# of Collaborated Projects: 7 results

# of Collaborated Products: 9 results
3. MATSUDA Yoko (20363187)

# of Collaborated Projects: 6 results

# of Collaborated Products: 66 results
4. KUDO Mitsuhiro (20256978)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. 佐々木紀彦 (80639063)

# of Collaborated Projects: 5 results

# of Collaborated Products: 21 results
6. MATSUSHITA AKIRA (70449263)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
7. 志智優樹 (20887187)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
8. YOSHIMURA HISASHI (70645241)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
9. FUJIWARA Yuri (70434131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMAMOTO Tetsushi (20453920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
11. Michishita Masaki (50434147)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
12. NAKAGAWA TAKAYUKI (40447363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. AZAKAMI DAIGO (80453934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. ICHIKAWA HITOSHI (30201924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAGASHIMA Masakazu (20256952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 落合和彦 (30550488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 盆子原誠 (50343611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 内田英二 (70176684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 中島敦夫 (10291725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 五味不二也 (40205620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
21. 新井富生 (20232019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
22. 眞田幸弘 (60406113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 佐久間康成 (10296105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 野中敬介 (30867809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. NAKAHIRA REI

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. AONO Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. Korc Murray

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. ISHIKAWA Fuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. MATSUDA Kouichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. TAKAHASHI Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
31. PENG Wei-Xia

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. YAMAMOTO Masami

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. TANAKA Noriko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. MIENO Makiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 金田大太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 岩田孝吉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 村山繁雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 石川直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 塚田晃三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 沢辺元司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHIWATA Toshiyuki 石渡 俊行

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Development of novel therapies by regulating epithelial and mesenchymal features of pancreatic cancerPrincipal Investigator

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Development of early diagnosis and new treatments for pancreatic cancer using cancer stem cell-specific glycansPrincipal Investigator

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Personalized therapy for pancreatic cancer focused on FGFR-4, a novel molecular targetPrincipal Investigator

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Regulation of nestin using microRNA: Examination for clinical application of pancreatic cancer therapyPrincipal Investigator

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ISHIWATA Toshiyuki 石渡俊行