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SUMIZAWA Tomoyuki  住澤 知之

ORCIDConnect your ORCID iD *help
… Alternative Names

住澤 知之  スミサワ トモユキ

SUMIZAWA Tomiyuki  住澤 知之

澄澤 知之  スミザワ トモユキ

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Researcher Number 90206582
Other IDs
Affiliation (based on the past Project Information) *help 2007 – 2008: University of Occupational and Environmental Health, Japan, 産業生態科学研究所, 講師
2004: 鹿児島大学, 大学院・医歯学総合研究科, 助手
1997 – 2001: 鹿児島大学, 医学部, 助手
1999: Kagoshima University, Faculty of Medicine, Research Associate, 医学部・腫瘍研究施設, 助手
1990 – 1995: 鹿児島大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Hygiene
Except Principal Investigator
Pathological medical chemistry / Cell biology / Biological Sciences / 血管生物学 / General medical chemistry
Keywords
Principal Investigator
SH-SY5Y細胞 / アクリルアミド / アポトーシス / 毒性発現機構 / シグナル伝達 / ミトコンドリア / p53 / 有害化学物質 / 中毒発症機構 / 環境中毒 … More
Except Principal Investigator
… More 血管新生 / チミジンホスホリラーゼ / MRP / 多剤耐性 / アポトーシス / プロモーター / PD-ECGF / エリスロポエチン / ノックアウトマウス / TPI / metastasis / シグナル伝達 / SH2ドメイン / 誘導遺伝子 / 細胞増殖 / シスプラチン耐性 / hypoxia / STAT / JAK / GS-X pump / SH2 domain / デオキシリボース / アドリアマイシン耐性 / angiogenesis / 転移 / 2-deoxy-L-ribose / 2-deoxy-D-ribose / Thymidine phosphorylase / 低酸素 / P-糖蛋白質 / 増殖抑制 / 細胞分化 / 分子生物学 / キメラ分子 / 活性化 / 情報伝達機構 / 受容体 / 分化 / 情報伝達 / サイトカイン / 不定型多剤耐性 / knock-out mouse / apoptosis / angipgenesis / 2deoxy-I-ribose / 2deoxy-D-ribose / thymidine phosphorylase / 白質脳症 / MNGIE / 2デオキシLリボース / 2デオキシDリボース / apotosis / 2-depxy-D-ribose / チミジン / PDーECGF / チトクロームC / アトポーシス / differentiation / tyrosine kinase / transcription factor / signal transduction / cytokine / erythropoietin / サブトラクション / 転写調節 / インターロイキン / チロシンキナーゼ / 転写因子 / Leukotriene C4 / Cisplatin-resistance / GS-Xポンプ / ロイコトリエンC4 / 重金属 / GS-X ポンプ / ロイコトリエンC_4 / Progesterone / Topoisomerase / Glutathione-S-transferase / Adriamycin / Multidrug resistance / P-glycoprotein / アドリアマイシン / プロゲステロン / トポイソメラーゼ / グルタチオンSトランスフェラーゼ / Tyrosine kinase / Activation / Dimerization / Epidermal growth factor / Erythropoietin / 受容体活性化 / Prognosis / Metastasis / Thrombomodulin / Colorectal carcinoma / Deoxyribose / Angiogenic factor / Thymidine Phosphorylase / 予後 / トロンボモジュリン / 大腸癌 / 血管新生因子 / Reversal of multidrug resistance / PAK-200 / dihydropyridine analogue / Cisplatin resistance / Adriamycin resistance / Atypical multidrug-resistant mutants / PAKー200 / 多剤耐性克服 / 2-デオキシ-L-リボース / 2-デオキシ-D-リボース / 腫瘍増殖 / invasion / Thymidine_phosphorylase / Apoptosis / HIF-1α / BN1P3 / 浸潤 / フルオロウリジン / トポイソメラーゼII / 造血因子 / 赤血球増多症 / 二量体化 / エリスロポエチン受容体 / 細胞膜蛋白質 / シスプラチンの排出ポンプ / シスプラチンの蓄積 / ヒト癌KB細胞 / 耐性克服 / PAKー104P / セファランチン / 副腎 / 薬剤結合部位 / Pー糖蛋白質 Less
  • Research Projects

    (20 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (28 People)
  •  The mechanism of p53-mediated mitochondrial dysfunction induced by toxic chemicalsPrincipal Investigator

    • Principal Investigator
      SUMIZAWA Tomoyuki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  腫瘍増殖・浸潤・転移を抑制する新規薬剤の開発

    • Principal Investigator
      秋山 伸一
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kagoshima University
  •  Analysis of the mechanisms for biological activities of thymidine phosphorylase

    • Principal Investigator
      FURUKAWA Tatsuhiko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kagoshima University
  •  Physiological function of thymidine phosphorylase and the involvement of the enzyme in tumor growth

    • Principal Investigator
      AKIYAMA Shinichi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kagoshima University
  •  チミジンホスホリラーゼ阻害剤による腫瘍増殖抑制とその基礎的研究

    • Principal Investigator
      古川 龍彦
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kagoshima University
  •  Growth and Differentiation through the Cytokine Receptors

    • Principal Investigator
      YOSHIMURA Akihiko
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Life Science, Kurume University
  •  造血幹細胞の増殖を制御するシグナル伝達分子群の解析

    • Principal Investigator
      吉村 昭彦
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kagoshima University
  •  エリスロポエチン受容体の情報伝達機構と細胞増殖およびがん化との関連

    • Principal Investigator
      吉村 昭彦
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kagoshima University
  •  P-糖蛋白質の関与しない多剤耐性の機構と、その克服方法の開発

    • Principal Investigator
      秋山 伸一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kagoshima University
  •  The mechanism of regulation of P-glycoprotein (Analysis of multidrug-resistant mutants that do not express P-glycoprotein)

    • Principal Investigator
      HARAGUCHI Misako
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kagoshima University
  •  Structure and function of an active efflux pump for cisplatin

    • Principal Investigator
      AKIYAMA Shinichi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kagoshima University
  •  サイトカイン受容体の構造と情報伝達機構の分子機序に関する共同研究

    • Principal Investigator
      吉村 昭彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kagoshima University
  •  エリスロポエチン受容体の情報伝達機構と細胞増殖およびがん化との関連

    • Principal Investigator
      吉村 昭彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kagoshima University
  •  チミジンホスホリラーゼ活性と血管新生の関連性について

    • Principal Investigator
      秋山 伸一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      血管生物学
    • Research Institution
      Kagoshima University
  •  The mechanism of angiogenesis by PD-ECGF

    • Principal Investigator
      AKIYAMA Shin-ichi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kagoshima University
  •  Structure and Signal Transduction of the Erythropoietin Receptor

    • Principal Investigator
      YOSHIMURA Akihiko
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Cancer Research Institute, Faculty of Medicine, Kagoshima University
  •  シスプラチン耐性機構の解析と耐性克服方法の開発

    • Principal Investigator
      秋山 伸一
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kagoshima University
  •  Pー糖蛋白質の関与しない多剤耐性の分子機構の解明と克服方法の開発

    • Principal Investigator
      秋山 伸一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kagoshima University
  •  Pー糖蛋白質の構造と機能の研究

    • Principal Investigator
      AKIYAMA Shin-ichi
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Kagoshima University
  •  Isolation and analysis of atypical multidrug-resistant mutants.

    • Principal Investigator
      AKIYAMA Shin-ichi
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kagoshima University

All 2009 2008 2007

All Journal Article Presentation

  • [Journal Article] Current Topicsラット肝由来の巨大な核酸蛋白質複合体vaultのX線結晶構造2009

    • Author(s)
      住澤知之、加藤公児、田中秀明
    • Journal Title

      実験医学 (印刷中)

      Pages: 0-0

    • Data Source
      KAKENHI-PROJECT-19590608
  • [Journal Article] Suppression of acrylamide toxicity by carboxyfullerene in human neuroblastoma cells in vitro.2009

    • Author(s)
      Tomoyuki Sumizawa, Hideki Igisu
    • Journal Title

      Archives of Toxicology (in press)

      Pages: 0-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590608
  • [Journal Article] The structure of rat liver vault at 3.5 angstrom resolution.2009

    • Author(s)
      Hideaki Tanaka, Koji Kato, Eiki Yamashita, Tomoyuki Sumizawa, 他5名
    • Journal Title

      Science 323

      Pages: 384-388

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590608
  • [Journal Article] Hyperosmotic stress up-regulates the expression of major vault protein in SW620 human colon cancer cells.2008

    • Author(s)
      Ryuji Ikeda, Ken-ichi Iwashita, Tomoyuki Sumizawa, 他16名
    • Journal Title

      Experimental Cell Research 314

      Pages: 3017-3026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590608
  • [Journal Article] Release of heat shock proteins from human neuroblastoma cells exposed to acrylamide.2008

    • Author(s)
      Tomoyuki Sumizawa and Hideki Igisu
    • Journal Title

      The Journal of Toxicological Sciences 33

      Pages: 117-122

    • NAID

      110006596037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590608
  • [Journal Article] Release of heat shock proteins from human neuroblastoma cells exposed to acrylamide2008

    • Author(s)
      住澤 知之
    • Journal Title

      The Journal of Toxicological Sciences 33

      Pages: 117-122

    • NAID

      110006596037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590608
  • [Journal Article] A vault ribonucleoprotein particle exhibiting 39-fold dihedral symmetry.2008

    • Author(s)
      Koji Kato, Hideaki Tanaka, Tomoyuki Sumizawa. 他4名
    • Journal Title

      Acta Crystallographica Section D Biological Crystallography 64

      Pages: 525-531

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590608
  • [Journal Article] Apoptosis induced by acrylamide in SH-SY5Y cells.2007

    • Author(s)
      Tomoyuki Sumizawa, Hideki Igisu
    • Journal Title

      Archives of Toxicology 81

      Pages: 279-282

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590608
  • [Journal Article] Apoptosis induced by acrylamide in SH-SY5Y cells2007

    • Author(s)
      住澤 知之
    • Journal Title

      Archives of Toxicology 81

      Pages: 279-282

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590608
  • [Presentation] アクリルアミド曝露によるヒト神経芽細胞腫由来SH-SY5Y細胞からの熱 ショックタンパク質の放出2008

    • Author(s)
      住澤知之
    • Organizer
      第26回産業医科大学学会総会
    • Place of Presentation
      福岡県北九州市八幡西区(産業医科大学)
    • Year and Date
      2008-10-30
    • Data Source
      KAKENHI-PROJECT-19590608
  • [Presentation] ヒト神経芽細胞腫由来SH-SY5Y細胞のアクリルアミド曝露によるアポトーシス誘導2008

    • Author(s)
      住澤知之
    • Organizer
      平成20年度 日本産業衛生学会 九州地方会
    • Place of Presentation
      福岡県北九州市八幡西区(産業医科大学)
    • Year and Date
      2008-07-18
    • Data Source
      KAKENHI-PROJECT-19590608
  • [Presentation] アクリルアミドがヒト神経芽細胞腫由来SH-SY5Y細胞に与える影響2008

    • Author(s)
      住澤知之
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会
    • Place of Presentation
      兵庫県神戸市(神戸ポートアイランド)
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-19590608
  • [Presentation] アクリルアミド曝露によるヒト神経芽細胞腫由来SH-SY5Y細胞からの熱ショックタンパク質の放出2008

    • Author(s)
      住澤 知之
    • Organizer
      第26回産業医科大学学会総会
    • Place of Presentation
      福岡県北九州市八幡西区(産業医科大学)
    • Year and Date
      2008-10-30
    • Data Source
      KAKENHI-PROJECT-19590608
  • 1.  AKIYAMA Shin-ichi (60117413)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 0 results
  • 2.  HARAGUCHI Misako (10244229)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 0 results
  • 3.  YOSHIMURA Akihiko (90182815)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 4.  FURUKAWA Tatsuhiko (40219100)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 5.  TANI Ayako (70284867)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  小松 正治
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  OHTSUBO Motoaki (10211799)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  IRA H. Pastan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MICHAEL M. Gottesman
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  PIRKER Robert
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  MIYAZONO Kohei
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  FOJO Antonio
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  NEUMANN Drorit
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  LODISH Harvey
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  HATAKEYAMA M
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  HARVEY Lodis
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MIYAJIMA Ats
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  宮寺 和孝
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  満尾 良一
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  中島 融一
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  PASTAN Ira H
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  GODDESMAN Mi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  GOTTESMAN Mi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  HELDIN Carlー
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  HELDIN Carl-henrich
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  CARL Heldin
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  宮島 篤
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  KOMATSU M
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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