• Search Research Projects
  • Search Researchers
  1. Back to previous page

YAMANAKA Kunitoshi  山中 邦俊

ORCIDConnect your ORCID iD *help
Researcher Number 90212290
Other IDs
External Links
Affiliation *help 2016 – 2018 : 熊本大学, 発生医学研究所, 准教授
2015 : 熊本大学, 学内共同利用施設等, 准教授
2014 : 熊本大学, 発生医学研究所, 准教授
2009 – 2011 : 熊本大学, 発生医学研究所, 准教授
2006 – 2008 : Kumamto University, Institute of Molecular Embryology and Genetics, Associate Professor … More
2002 – 2006 : 熊本大学, 発生医学研究センター, 助教授
2000 – 2001 : 熊本大学, 発生医学研究センター, 助手
1990 – 1995 : 熊本大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Molecular biology / Molecular biology / General medical chemistry
Except Principal Investigator
Biological Sciences / 遺伝学 / Molecular biology / Functional biochemistry / Basic Section 52020:Neurology-related / Neurology
Keywords
Principal Investigator
p97 / VCP / ATPase / ポリグルタミン病 / 分子シャペロン / molecular chaperone / 遺伝性痙性対麻痺 / AAAタンパク質 / neurodegenerative disease / hereditary spastic paraplegia … More / 神経変性疾患 / AAA protein / 線虫 / polyglutamine disease / spastin / AAAシャペロン / 生体分子 / fidgetin / CDC-48 / mukB / ユビキチン / 染色体分配 / DNA結合蛋白質 / UBXN-6 / 低温ショック蛋白質 / 大腸菌 / マルチコピーサプレッサー / C. elegans / C.elegans / cspE / cspC … More
Except Principal Investigator
ATPase / 染色体分配 / 分子シャペロン / AAAタンパク質 / ミトコンドリア / 微小管 / プロテアーゼ / MukB蛋白 / シャペロン / 神経変性疾患 / MukB / 線虫 / 大腸菌 / ポリグルタミン病 / 高速原子間力顕微鏡 / protease / アミロイドーシス / MutS / 複製フォーク / プロテアソーム / DNAスライデングクランプ / 膜蛋白質 / FtsH / AAA protein / 抑制変異 / ATP / ピルビン酸脱水素酵素 / DNA結合蛋白 / SeqA / chromosome partitioning / 膜蛋白 / chaperone / 複製装置 / DNAメチラーゼ / タンパク質凝集体 / トランスサイレチン / ftsH遺伝子 / 大腸菌ゲノム / トランスロケーション / 遺伝性痙性対麻痺 / ApoE5 / ApoE7 / spastin / Katanin / DNAジャイレース / 線虫の性決定 / muk遺伝子 / プラスミドの複製 / σ因子 / 染色体DNA / Aurora Bキナーゼ / DNAメチレーション / sigma^<32> / mukB遺伝子 / 分配機構 / hereditary spastic paraplegia / ATP加水分解 / 成長ホルモン / ApoCーIII / 性決定機構 / GTP結合能 / E. coli / DNA sliding clump / Muts / sister chromosome cohesion / SeqA protein / MukB protein / 無核細胞 / 膜タンパク質 / 転写制御 / リボソーム品質管理 / DnaA / secY遺伝子 / ペニシリン結合タンパク質 / σ32 / 複製起点 / DNA結合能 / immunofluorescence method / プラスミド / 塩基配列 / DNAー蛋白複合体 / 姉妹染色体接着 / tolC遺伝子 / ftsH gene / DNA binding protein / 品質管理機構 / アルコール脱水素酵素 / 蛍光抗体法 / ATP依存性プロテアーゼ / ドラッグリポジショニング / Muk蛋白 / ミスマッチ修復 / 細胞分裂 / microtubule / C. elegans / hop変異 / 変異核 / ATPアーゼ / アポリポ蛋白質 / 核様体 / エキソヌクレアーゼV / コイルドコイル蛋白 / FtsH蛋白 / fur遺伝子 / DNA結合 / muk gene / ペニシリン結合蛋白 / タンパク質の品質管理 / AAA タンパク質 / 細胞内フィラメント / katanin / C.elegans / Fプラスミド / ポリグルタミン凝集体 / genetic diseases / β-ラクタマーゼ / ClpX / 細胞内タンパク質分解 / 膜会合細胞骨格様構造 / TDP-43 / 病態モデル / 分泌蛋白 / membrane protein / プラスミドの分配 / Bcs1p / コールドショック蛋白 / ATPasc / スピロゾーム / 大腸菌変異体 / アミロイド / トポイソメラ-ゼ / DNAメチールトランスフェラーゼ / p97/VCP/CDC-48/Cdc48 / 26Sプロテアソーム / mitochondria / アンフォールディング / タンパク質の局在化 / ヒトアポリポタンパク / muk変異 / シャベロン / SeqA蛋白質 / 大腸菌染色体の分配 / ATP-dependent protease / replication fork / タンパク質のアンフォールディング / 遺伝性疾患 / 抗体治療 / ジャイレ-ス / ヌクレオチド結合能 / Muk protein / cold shock protein / DNA methyltransferase / MACS / 蛋白の局在化 / 酵母 / fts遺伝子 / 複製開始 / protein aggregation / 疾患モデル / p97/CDC-48/Cdc48 / タンパク質分解 / アルコ-ル脱水素酵素 / 結晶構造 / MukB蛋白質 / polyglutamine disease / GTP結合 Less
  • Research Projects

    (21results)
  • Research Products

    (56results)
  • Co-Researchers

    (40People)
  •  根治療法の切り札アミロイド・ブレイカー開発とそれを用いた毒性メカニズム探求Ongoing

    • Principal Investigator
      植田 光晴
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Kumamoto University
  •  リング状AAA型シャペロンの基質への作用機構のin vitro系による解明Ongoing

    • Principal Investigator
      小椋 光
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kumamoto University
  •  AAA型シャペロンCDC-48の新規制御機構「クリップモデル」の検証Principal InvestigatorOngoing

    • Principal Investigator
      山中 邦俊
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Kumamoto University
  •  Novel experimental model of TTR amyloidosis using TTR fragments

    • Principal Investigator
      植田 光晴
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Kumamoto University
  •  Molecular mechanisms of AAA proteins revealed by biochemical analyses and high-speed atomic force microscopic observations

    • Principal Investigator
      OGURA Teru
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kumamoto University
  •  Mechanisms of remodeling and quality control of proteins by AAA chaperones

    • Principal Investigator
      OGURA Teru
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Molecular analysis of C.elegans AAA proteins related to genetic diseases and developmental disordersPrincipal Investigator

    • Principal Investigator
      YAMANAKA Kunitoshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Molecular, cellular, and developmental studies on AAA chaperones

    • Principal Investigator
      OGURA Teru
    • Project Period (FY)
      2002 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Molecular and cellular biology of C. elegans AAA proteins involved in human genetic diseasesPrincipal Investigator

    • Principal Investigator
      YAMANAKA Kunitoshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  プロテオバクテリアにおけるメチル化DNA関連遺伝子群の網羅的研究

    • Principal Investigator
      平賀 壮太
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Structural and functional studies on AAA proteins in E. coli and C. elegans.

    • Principal Investigator
      OGURA Teru
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Molecular biology
    • Research Institution
      Kumamoto University
  •  DYNAMIC LOCALIZATION OF PROTEINS AND CHROMOSOME IN BACTERIA

    • Principal Investigator
      HIRAGA Sota
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Molecular biology
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Genes of Chromosome Partition and the FtsH Protein

    • Principal Investigator
      HIRAGA Sota
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  大腸菌染色体分配に関与するDNA結合因子の遺伝生化学的解析Principal Investigator

    • Principal Investigator
      山中 邦俊
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      Kumamoto University
  •  真核細胞の小胞体経路に類似した大腸菌の膜蛋白局在化機構

    • Principal Investigator
      小椋 光
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  大腸菌における駆動力発生酵素および細胞質性フィラメントの分子生物学的研究

    • Principal Investigator
      平賀 壯太
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      遺伝学
    • Research Institution
      Kumamoto University
  •  Prokaryotic force-generating enzyme and protein transport.

    • Principal Investigator
      HIRAGA Sota
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  真核細胞の小胞体経路に類似した大腸菌の膜蛋白局存化機構

    • Principal Investigator
      OGURA Teru
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  大腸菌における染色体分配を司る遺伝子群の研究

    • Principal Investigator
      平賀 壮太
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      遺伝学
    • Research Institution
      Kumamoto University
  •  大腸菌ゲノムの分配を可る遺伝子群の全体像

    • Principal Investigator
      HIRAGA Sota
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  遺伝性疾患及び細胞増殖に関与する遺伝子群の分子遺伝学的研究

    • Principal Investigator
      平賀 壯太
    • Project Period (FY)
      1987 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      遺伝学
    • Research Institution
      Kumamoto University

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2004 Other

All Journal Article Presentation

  • [Journal Article] CDC-48/p97 is required for proper meiotic chromosome segregation via controlling AIR-2/Aurora B kinase localization in Caenorhabditis elegans.2016

    • Author(s)
      Miyazaki J, Nishizawa H, Kambayashi A, Ito M, Noda Y, Terasawa S,Kato T,Miyamura H,Shiogama K,Sekiya T,Kurahashi H,Fujii T
    • Journal Title

      J Struct Biol.

      Volume : 48 Pages : 20-25

    • DOI
      10.1016/j.jsb.2012.06.009
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462540, KAKENHI-PROJECT-21370076, KAKENHI-PROJECT-24370056, KAKENHI-PROJECT-24659432
  • [Journal Article] Characterization of C-terminal adaptors, UFD-2 and UFD-3, of CDC-48 on the polyglutamine aggregation in C. elegans.2015

    • Author(s)
      Murayama, Y., Ogura, T., and Yamanaka, K.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume : 459 Pages : 154-160

    • DOI
      10.1016/j.bbrc.2015.02.088
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24370056
  • [Journal Article] Caenorhabditis elegans fidgetin homolog FIGL-1, a nuclear-localized AAA ATPase, binds to SUMO.2012

    • Author(s)
      Onitake, A., Yamanaka, K., Esaki, M., and Ogura.T.
    • Journal Title

      Struct. Biol

      Volume : 179(Epub 2012 May 7.) Pages : 143-151

    • DOI
      10.1016/j.jsb.2012.04.022
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24370056, KAKENHI-PROJECT-24659432, KAKENHI-PROJECT-24770189, KAKENHI-PLANNED-19058012
  • [Journal Article] The C-terminal α-helix of SPAS-1, a Caenorhabditis elegans spastin homologue, is crucial for microtubule severing.2012

    • Author(s)
      Onitake, A., Matsushita-Ishiodori, Y., Johjima, A., Esaki, M., Ogura, T., and Yamanaka, K.
    • Journal Title

      Struct. Biol

      Volume : 179(Epub 2012 Apr 27.) Pages : 138-142

    • DOI
      10.1016/j.jsb.2012.04.010
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24370056, KAKENHI-PROJECT-24659432, KAKENHI-PROJECT-24770189, KAKENHI-PLANNED-19058012
  • [Journal Article] Recent advances in p97/VCP/Cdc48 cellular functions.2012

    • Author(s)
      Yamanaka, K., Sasagawa, Y., and Ogura, T.
    • Journal Title

      Biochim. Biophys. Acta

      Volume : 1823 Issue : 1 Pages : 130-137

    • Publisher
      Elsevier
    • DOI
      10.1016/j.bbamcr.2011.07.001
    • PMID
      21781992
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] Positive cooperativity of the p97 AAA ATPase is critical for essential functions2011

    • Author(s)
      Nishikori, S., Esaki, M., Yamanaka, K., Sugimoto, S., and Ogura, T.
    • Journal Title

      Journal of Biological Chemistry

      Volume : 286 Pages : 15815-15820

    • DOI
      10.1074/jbc.m110.201400
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012, KAKENHI-PROJECT-22880034, KAKENHI-PROJECT-23590521
  • [Journal Article] C. elegans UBX cofactors for CDC-48/p97 control spermatogenesis.2010

    • Author(s)
      Sasagawa, Y., Yamanaka, K. Saito-Sasagawa, Y., and Ogura, T.
    • Journal Title

      Genes Cells 15

      Pages : 1201-1215

    • DOI
      10.1111/j.1365-2443.2010.01454.x
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] AAA+ chaperone ClpX regulates dynamics of prokaryotic cytoskeletal protein FtsZ.2010

    • Author(s)
      Sugimoto, S., Yamanaka, K., Nishikori, S., Miyagi, A., Ando, T., and Ogura, T.
    • Journal Title

      J. Biol. Chem.

      Volume : 285 Pages : 6648-6657

    • DOI
      10.1074/jbc.m109.080739
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] AAA+ chaperone ClpX regulates dynamics of prokaryotic cytoskeletal protein FtsZ.2010

    • Author(s)
      Sugimoto, S., Yamanaka, K., Nishikori, S., Miyagi, A.,o, T., Ogura, T.
    • Journal Title

      J. Biol. Chem. 285

      Pages : 6648-6657

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] Caenorhabditis elegans p97 controls germline-specific sex determination by controlling TRA-1 level in a CUL-2-dependent manner.2009

    • Author(s)
      Sasagawa, Y., Otani, M., Higashitani, N., Higashitani, A., Sato, K., Ogura, T., and Yamanaka, K.
    • Journal Title

      J. Cell Sci.

      Volume : 122 Pages : 3663-3672

    • DOI
      10.1242/jcs.052415
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] Conserved aromatic and basic amino acid residues in the pore region of C. elegans spastin play critical roles in microtubule-severing.2009

    • Author(s)
      Matsushita-Ishiodori, Y., Yamanaka, K., Hashimoto, H., Esaki, M., and Ogura, T.
    • Journal Title

      Genes Cells

      Volume : 14 Pages : 925-940

    • DOI
      10.1111/j.1365-2443.2009.01320.x
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] Caenorhabditis elegans p97 controls germline-specific sex determination by controlling TRA-1 level in a CUL-2-dependent manner.2009

    • Author(s)
      Sasagawa, Y., Otani, M., Higashitani, N., Higashitani, A., Sato, K., Ogura, T., Yamanaka, K.
    • Journal Title

      J. Cell Sci. 122

      Pages : 3663-3672

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] onserved aromatic and basic amino acid residues in the pore region of C. elegans spastin play critical roles in microtubule-severing.2009

    • Author(s)
      Matsushita-Ishiodori, Y., Yamanaka, K., Hashimoto, H., Esaki, M., Ogura, T.
    • Journal Title

      Genes Cells 14

      Pages : 925-940

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] p97 homologs from C. elegans, CDC-48.1 and CDC-48.2, suppress the aggregate formation of huntingtin exon1 containing expanded polyQ repeat.2008

    • Author(s)
      Nishikori, S., Yamanaka, K., Sakurai, T., Esaki, M., and Ogura, T.
    • Journal Title

      Genes Cells

      Volume : 13 Pages : 827-838

    • DOI
      10.1111/j.1365-2443.2008.01214.x
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] From the common molecular basis of the AAA protein to various energy-dependent and -independent activities of AAA proteins.2008

    • Author(s)
      Ogura, T., Matsushita-Ishiodori, Y., Johjima, A., Nishizono, M., Nishikori, S., Esaki, M., and Yamanaka, K.
    • Journal Title

      Biochem. Soc. Trans.

      Volume : 36 Pages : 68-71

    • DOI
      10.1042/bst0360068
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] Involvement of HMG-12 and CAR-1 in the cdc-48.1 expression of Caenorhabditis elegans.2008

    • Author(s)
      Yamauchi, S., Higashitani, N., Otani, M., Higashitani, A., Ogura, T., and Yamanaka, K.
    • Journal Title

      Dev. Biol.

      Volume : 318 Pages : 348-359

    • DOI
      10.1016/j.ydbio.2008.02.057
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] T. p97 homologs from C. elegans, CDC-48. 1 and CDC-48. 2, suppress the aggregate formation of huntingtin exon1 containing expanded polyQ repeat.2008

    • Author(s)
      Nishikori, S., Yamanaka, K., Sakurai, T., Esaki, M., Ogura, T.
    • Journal Title

      Genes Cells 13

      Pages : 827-838

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] Differential expression pattern of UBX family genes in Caenorhabditis elegans.2007

    • Author(s)
      Yamauchi, S., Sasagawa, Y., Ogura, T., and Yamanaka, K.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume : 358 Pages : 545-552

    • DOI
      10.1016/j.bbrc.2007.04.163
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] Caenorhabditis elegans p97/CDC-48 is crucial for progression of meiosis I.2007

    • Author(s)
      Sasagawa, Y., Yamanaka, K., Nishikori, S., and Ogura, T.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume : 358 Pages : 920-924

    • DOI
      10.1016/j.bbrc.2007.05.022
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] The C. elegans homologue of the spastic paraplegia protein, spastin, disassembles microtubules.2007

    • Author(s)
      Matsushita-Ishiodori, Y., Yamanaka, K., and Ogura, T.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume : 359 Pages : 157-162

    • DOI
      10.1016/j.bbrc.2007.05.086
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] ER E3 ubiquitin ligase HRD-1 and its specific partner chaperone BiP play important roles in ERAD and developmental growth in C. Elegans.2007

    • Author(s)
      Sasagawa, Y., Yamanaka, K., and Ogura, T.
    • Journal Title

      Genes Cells

      Volume : 12 Pages : 1063-1073

    • DOI
      10.1111/j.1365-2443.2007.01108.x
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] ER E3 ubiquitin ligase HRD-1 and its specific partner chaperone BiP play important roles in ERAD and developmental growth in C. elegans.2007

    • Author(s)
      Sasagawa, Y., Yamanaka, K., Ogura, T.
    • Journal Title

      Genes Cells 12

      Pages : 1063-1073

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Journal Article] An AAA protease FtsH can initiate proteolysis from internal sites of a model substrate, apo-flavodoxin.2006

    • Author(s)
      Okuno, T., Yamanaka, K., Ogura, T.
    • Journal Title

      Genes Cells 11

      Pages : 261-268

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16570147
  • [Journal Article] Analysis of the two p97/VCP/Cdc48p proteins of Caenorhabditis elegans and their suppression of polyglutamine-induced protein aggregation.2004

    • Author(s)
      K. Yamanaka
    • Journal Title

      J. Struct. Biol. 146

      Pages : 242-250

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14037256
  • [Journal Article] Analysis of the two p97/VCP/Cdc48p proteins of Caenorhabditis elegans and their suppression of polyglutamine・induced protein aggregation.2004

    • Author(s)
      K. Yamanaka
    • Journal Title

      J. Struct. Biol. 146

      Pages : 242-260

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14037256
  • [Journal Article] 線虫を用いたAAA蛋白質に起因する神経変性疾患モデル2004

    • Author(s)
      山中邦俊
    • Journal Title

      蛋白質核酸酵素 49

      Pages : 1124-1126

    • Data Source
      KAKENHI-PROJECT-14037256
  • [Journal Article] 線虫を用いたAAA蛋白質に起因する神経変性疾患モデル2004

    • Author(s)
      山中 邦俊
    • Journal Title

      蛋白質 核酸 酵素 49

      Pages : 1124-1126

    • Data Source
      KAKENHI-PROJECT-16570147
  • [Journal Article] Identification of a cysteine residue important for the ATPase activity of C.elegans fidgetin homologue.2004

    • Author(s)
      Yakushiji, Y., Yamanaka, K., Ogura, T.
    • Journal Title

      FEBS Lett. 578

      Pages : 191-197

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16570147
  • [Journal Article] Analysis of the two p97/VCP/Cdc48p proteins of Caenorhabditis elegans and their suppression of polyglutamine-induced protein aggregation.2004

    • Author(s)
      Yamanaka, K.
    • Journal Title

      J.Struct.Biol. 146

      Pages : 242-250

    • Data Source
      KAKENHI-PROJECT-16570147
  • [Journal Article] Analysis of the two p97/VCP/Cdc48p proteins of Caenorhabditis elegans and their suppression of polyglutamine-induced protein aggregation.2004

    • Author(s)
      Yamanaka, K.
    • Journal Title

      J.Struct.Biol. 146

      Pages : 242-250

    • Data Source
      KAKENHI-PROJECT-14037256
  • [Journal Article] Flavodoxin, a new fluorescent substrate for monitoring proteolytic activity of FtsH lacking a robust unfolding activity.

    • Author(s)
      Okuno, T., Yamanaka, K., Ogura, T.
    • Journal Title

      J.Struc.Biol. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16570147
  • [Journal Article] Mutational analysis of the functional motifs in the ATPase domain of C.elegans fidgetin homologue FIGL-1 : Firm evidence for an intersubunit catalysis mechanism of ATP hydrolysis by AAA ATPases.

    • Author(s)
      Yakushiji, Y., Nishikori, S., Yamanaka, K., Ogura, T.
    • Journal Title

      J.Struc.Biol. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16570147
  • [Journal Article] Characterization of mutants of the Escherichia coli AAA protease, FtsH, carrying a mutation in the central pore region

    • Author(s)
      Okuno, T., Yamanaka, K., Ogura, T.
    • Journal Title

      J.Struc.Biol. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16570147
  • [Presentation] Elucidation of UBXN-6 function in CDC-48-regulated ERAD in C. elegans2017

    • Author(s)
      Mojumder, S., Sawamura, R., Ogura, T., and Yamanaka, K.
    • Organizer
      第40回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16K08594
  • [Presentation] Adaptors of p97 and disease-associated p97 mutations.2014

    • Author(s)
      Yamanaka, K., Murayama, Y., and Ogura, T.
    • Organizer
      231st IMEG seminars & Minisymposium
    • Place of Presentation
      熊本市 熊本大学発生医学研究所
    • Data Source
      KAKENHI-PROJECT-24370056
  • [Presentation] High-speed AFM imaging of the 26S proteasome dynamics.2014

    • Author(s)
      Okuno, T., Noi, K., Okawa, A., Tsuchiya, H., Saeki, Y., Takahashi, K., Inobe, T., Yamanaka, K., and Ogura, T.
    • Organizer
      231st IMEG seminars & Minisymposium
    • Place of Presentation
      熊本市 熊本大学発生医学研究所
    • Data Source
      KAKENHI-PROJECT-24370056
  • [Presentation] 高速AFMによる26Sプロテアソームのダイナミクス解析.2013

    • Author(s)
      奥野 貴士, 野井 健太郎, 大川 阿紀子, 土屋 光, 佐伯 泰, 高橋 一暢, 伊野部 智由, 山中 邦俊, 小椋 光
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸市、神戸国際展示場
    • Data Source
      KAKENHI-PROJECT-24370056
  • [Presentation] 線虫を用いた疾患型変異CDC-48/p97/VCPの機能解析2013

    • Author(s)
      山中 邦俊, 村山 佑樹, 小椋 光
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸市、神戸国際展示場
    • Data Source
      KAKENHI-PROJECT-24370056
  • [Presentation] Functional analysis of disease-associated mutant CDC-48/p97/VCP in C. elegans.2013

    • Author(s)
      Yamanaka, K., Murayama, Y., and Ogura, T.
    • Organizer
      EMBO Workshop on AAA+ Proteins
    • Place of Presentation
      Commundo Hotel, Neuss, Germany.
    • Data Source
      KAKENHI-PROJECT-24370056
  • [Presentation] Dynamics of p97 and the 26S proteasome in action revealed by high-speed atomic force microscopy.2013

    • Author(s)
      Ogura, T., Noi, K., Okuno, T., Arita-Morioka, K., Yamamoto, D., Okawa, A., Tsuchiya, H., Saeki, Y., Ando, T., Esaki, M., and Yamanaka, K.
    • Organizer
      EMBO Workshop on AAA+ Proteins
    • Place of Presentation
      Commundo Hotel, Neuss, Germany.
    • Invited
    • Data Source
      KAKENHI-PROJECT-24370056
  • [Presentation] AAA chaperones, focusing on the molecular mecanism of p97.2013

    • Author(s)
      Ogura, T., Noi, K., Arita-Morioka, K., Yamamoto, D., Ando, T., Nishikori, S., Esaki, M., and Yamanaka, K.
    • Organizer
      EMBO Conference The biology of molecular chaperones
    • Place of Presentation
      Margherita de Pula, Italy
    • Invited
    • Data Source
      KAKENHI-PROJECT-24370056
  • [Presentation] Multiple aspects of multifunctional p97.2011

    • Author(s)
      Ogura, T., Noi, K., Arita-Morioka, K., Esaki, M., Murayama, Y., and Yamanaka, K.
    • Organizer
      9th International Conference on AAA Protein
    • Place of Presentation
      熊本市国際交流会館, Kumamoto, Japan.
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Presentation] C. elegans CDC-48/p97 controls germline-specific sex determination.2010

    • Author(s)
      Yamanaka, K., Sasagawa, Y., and Ogura, T.
    • Organizer
      BIT Life Sciences' 3rd Annual Protein and Peptide Conference (PepCon-2010)
    • Place of Presentation
      Beijing, China
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Presentation] 線虫を用いたp97/VCP/CDC48の機能解析2010

    • Author(s)
      山中邦俊
    • Organizer
      新潟脳神経研究会第290回例会
    • Place of Presentation
      新潟大学脳研究所新潟
    • Year and Date
      2010-06-04
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Presentation] Involvement of C.elegans p97-cofactor complexes in sex determination.2010

    • Author(s)
      Yamanaka, K.
    • Organizer
      The 3rd International Symposium on Protein Community
    • Place of Presentation
      ホテル日航奈良Nara, Japan
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Presentation] Involvement of C. elegans p97-cofactor complexes in sex determination.2010

    • Author(s)
      Yamanaka, K., Sasagawa, Y., Murayama, Y., and Ogura, T.
    • Organizer
      The 3rd International Symposium on Protein Community
    • Place of Presentation
      ホテル日航奈良, Nara, Japan
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Presentation] C.elegans CDC-48/p97 controls germline-specific sex determination.2010

    • Author(s)
      Yamanaka, K.
    • Organizer
      BIT Life Sciences' 3rd Annual Protein and Peptide Conference (PepCon-2010)
    • Place of Presentation
      International Convention Center, Beijing, China
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Presentation] Roles of p97/VCP, a multifunctional AAA chaperone, in protein oligomerization and aggregation in neurodegenerative diseases.2009

    • Author(s)
      Ogura, T., Nishikori, S., Yamanaka, K., and Esaki, M.
    • Organizer
      BIT Life Sciences' 2_<nd> Annual Protein and Peptide Conference (PepCon-2009)
    • Place of Presentation
      Seoul, South Korea
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Presentation] Molecular mechanisms of homologs of spastin and p97/VCP related to human genetic disorders.2009

    • Author(s)
      Ogura, T., Matsushita-Ishiodori, Y., Yamanaka, K., Nishikori, S., and Esaki, M.
    • Organizer
      8th International Conference on AAA Proteins
    • Place of Presentation
      Toronto, Canada
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Presentation] C.elegans p97/CDC-48UFD-1-NPL-4 controls germline specific sex determination by regulating CUL-2-mediated TRA-1 degradation.2009

    • Author(s)
      Yamanaka, K.
    • Organizer
      8th International Conference on AAA Proteins
    • Place of Presentation
      Toronto, Canada
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Presentation] p97/CDC-48.1による線虫生殖細胞の性決定の制御2008

    • Author(s)
      山中邦俊
    • Organizer
      第31回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Presentation] Functional analysis of p97NCP in C. elegans.2007

    • Author(s)
      Yamanaka, K.
    • Organizer
      The 7th International conference on AAA proteins
    • Place of Presentation
      Cirencester, UK
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Presentation] C. elegans p97, HRD-1 and BiP are required for ERAD and developmental growth.2007

    • Author(s)
      Yamanaka, K.
    • Organizer
      16th biennial International C. elegans conference
    • Place of Presentation
      UCLA, USA.
    • Data Source
      KAKENHI-PLANNED-19058012
  • [Presentation] ヒト疾患関連AAAタンパク質BCS1Lの酵母ホモログBcs1pの機能解析

    • Author(s)
      澤村 理英、江崎 雅俊、山中 邦俊、小椋 光
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜市 パシフィコ横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24370056
  • [Presentation] ポリグルタミン凝集体形成における線虫CDC-48 C末端アダプターの役割

    • Author(s)
      村山 佑樹、小椋 光、山中 邦俊
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜市 パシフィコ横浜
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24370056
  • [Presentation] Visualization of dynamics of the 26S proteasome and proteasome-substrate complexes by high-speed AFM

    • Author(s)
      Okuno, T., Noi, K., Okawa, A., Tsuchiya, H., Saeki, Y., Takahashi, K., Inobe, T., Yamanaka, K., and Ogura, T.
    • Organizer
      Key Forum: From Stem Cells to Organs
    • Place of Presentation
      熊本市 熊本市医師会館
    • Year and Date
      2014-09-04 – 2014-09-05
    • Data Source
      KAKENHI-PROJECT-24370056
  • 1.  OGURA Teru (00158825)
    # of Collaborated Projects : 14results
    # of Collaborated Products : 42results
  • 2.  HIRAGA Sota (40027321)
    # of Collaborated Projects : 8results
    # of Collaborated Products : 0results
  • 3.  NIKI Hironori (70208122)
    # of Collaborated Projects : 7results
    # of Collaborated Products : 0results
  • 4.  YAMAZOE Mitsuyoshi (00284745)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 0results
  • 5.  ESAKI Masatoshi (70437911)
    # of Collaborated Projects : 3results
    # of Collaborated Products : 14results
  • 6.  ALINE Jaffe
    # of Collaborated Projects : 3results
    # of Collaborated Products : 0results
  • 7.  植田 光晴 (60452885)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 8.  水口 峰之 (30332662)
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 9.  JAFFE Aline
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 10.  BERND Bukau
    # of Collaborated Projects : 2results
    # of Collaborated Products : 0results
  • 11.  OKUNO Takashi (80411031)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 4results
  • 12.  北岡 光彦 (30117345)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 13.  前田 英雄 (90094044)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 14.  森 浩禎 (90182203)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 15.  野井 健太郎 (30588405)
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 16.  BEGG Kenneth j.
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 17.  VINELLA Daniel
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 18.  BOULOC Philippe
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 19.  DONACHIE Wil
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 20.  DONACHIE William d.
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 21.  KENIIETH J.B
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 22.  WILLIAM.D.DO ドナヒー
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 23.  DANIEL Vinel
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 24.  PHILIPPE Bou
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 25.  CUTTING Simo
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 26.  SCHUMANN Wol
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 27.  RUTMAN Andre
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 28.  AMOS Oppenhe
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 29.  BUKAU Bernd
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 30.  SIMON Cutting
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 31.  WOLFGANG Schumann
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 32.  ANDREW Joel Rutman
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 33.  OPPENHEIM Amos B
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 34.  SIMON Cuttin
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 35.  WOLFGANG Sch
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 36.  ANDREW JOEL
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 37.  OPPENHEIM Am
    # of Collaborated Projects : 1results
    # of Collaborated Products : 0results
  • 38.  杉本 真也
    # of Collaborated Projects : 0results
    # of Collaborated Products : 1results
  • 39.  藤井 多久磨
    # of Collaborated Projects : 0results
    # of Collaborated Products : 1results
  • 40.  東谷 篤志
    # of Collaborated Projects : 0results
    # of Collaborated Products : 1results

URL :

Are you sure that you want to connect your ORCID iD to this researcher?

Information FAQ News Terms of Use

Powered by NII kakenhi