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KOMATSU MITSUHISA  駒津 光久

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Komatsu Mitsuhisa  駒津 光久

KOMATSU Mitsuhisa  駒津 光久

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Researcher Number 90221978
Other IDs
External Links
Affiliation (Current) 2025: 信州大学, 学術研究院医学系, 教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 信州大学, 学術研究院医学系, 教授
2014 – 2018: 信州大学, 学術研究院医学系, 教授
2012 – 2013: 信州大学, 医学部, 教授
2010 – 2011: 信州大学, 医学系研究科, 教授
2009: Shinshu University, 医学系研究科, 講師 … More
2006 – 2007: 信州大学, 大学院・医学系研究科, 講師
2005: Shinshu University Graduate School, Department of Aging Medicine and Geriatrics, Assistant Professor, 医学部附属病院, 講師
2003 – 2005: 信州大学, 大学院・医学研究科, 講師
2002: 信州大学, 医学部附属病院, 助手
2001: 信州大学, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Endocrinology / Basic Section 54040:Metabolism and endocrinology-related / Endocrinology / Metabolomics
Except Principal Investigator
Endocrinology / Obstetrics and gynecology
Keywords
Principal Investigator
ブドウ糖 / インスリン分泌 / cAMP / インクレチン / インスリン / 膵β細胞 / パルミチン化 / type 2 diabetes / secretion / insulin release … More / 膵ベータ細胞 / 糖尿病 / PGRMC1 / プロテオーム解析 / 甘味受容体 / NADPH / パルミチル化 / branched-chian amino acids / proteosome / acvlation / プロテオーム / Ca2+ / acylation / 細胞内Ca^<2+>濃度 / アシル化 / 蛋白のアシル化 / 2型糖尿病 / カルシウム / アシル化蛋白 … More
Except Principal Investigator
vitamin D3 / PPAR / phage display system / transcriptional mediator / nuclear receptor / クローニング / リガンド / 相互作用 / 転写因子 / クロストーク / VDR / 共役因子 / T7ファージディスプレイ / ファージディスプレイ法 / 転写共役因子 / 核受容体 / 転写調節子 / 膣β組胞 / インスリンプロモーター / 転写調節因子 / 膵β細胞 / エストロゲン Less
  • Research Projects

    (9 results)
  • Research Products

    (93 results)
  • Co-Researchers

    (10 People)
  •  ブドウ糖によるインスリン分泌を制御する新規分子PGRMC1の生理的意義の解明Principal Investigator

    • Principal Investigator
      駒津 光久
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Shinshu University
  •  Identification of novel molecular mechanisms regulating insulin secretion from pancreatic beta cells and their physiological significancePrincipal Investigator

    • Principal Investigator
      Komatsu Mitsuhisa
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Shinshu University
  •  Elucidation of three new molecular bases in the mechanisms of insulin secretionPrincipal Investigator

    • Principal Investigator
      Komatsu Mitsuhisa
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Shinshu University
  •  Insight into mechanisms of insulin secretion induced by KATP-independent action and incretinPrincipal Investigator

    • Principal Investigator
      KOMATSU Mitsuhisa
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Shinshu University
  •  The effect of estrogen for carbohydrate metabolism in pancreatic beta cells

    • Principal Investigator
      NISHIO Shin-ichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Shinshu University
  •  Identification of novel acylated proteins regulating insulin secretion and exploration of their physiological significancePrincipal Investigator

    • Principal Investigator
      KOMATSU Mitsuhisa
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Shinshu University
  •  Search for novel mechanisms of insulin secretion by combination of proteom analysis and HPLCPrincipal Investigator

    • Principal Investigator
      KOMATSU Mitsuhisa
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Shinshu University
  •  Cloning of nuclear receptor specific co-factor by phage display system

    • Principal Investigator
      MIYAMOTO Takahide
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Shinshu University
  •  A Study on Acylation-Regulated Membrane Proteins Involved in Insulin ExocytosisPrincipal Investigator

    • Principal Investigator
      KOMATSU Mitsuhisa
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Shinshu University

All 2019 2018 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book

  • [Book] KATP Channel-Independent Pathway and the Glucoreceptor. In: Kojima I. (eds) Glucose-sensing Receptor in Pancreatic Beta-cells.2018

    • Author(s)
      Aizawa T and Komatsu M
    • Publisher
      Springer, Singapore
    • ISBN
      9789811300011
    • Data Source
      KAKENHI-PROJECT-16K09799
  • [Book] Bariatric surgery on obese type 2 diabetes patients. Advanced Bariatric and Metabolic Surgery2012

    • Author(s)
      Mori J, Sato Y, Komatsu M
    • Publisher
      Edited by Chin-Kun Huang, In Tech
    • Data Source
      KAKENHI-PROJECT-21591128
  • [Book] アミノ酸, 脂肪酸とインスリン分泌 糠尿病学2007

    • Author(s)
      駒津光久
    • Total Pages
      5
    • Publisher
      西村書店
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Book] Glucose and nutrient-induced increase in insulin secretion in the absence of a rise in[Ca2+]i. In Commentaries on Perspectives in Diabetes2006

    • Author(s)
      Komatsu M, Schermerhorn T, Noda M, Straub SG, Aizawa T, Sharp G
    • Total Pages
      3
    • Publisher
      Robertson RP, Ed., American Diabetes Association
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Book] Pancreatic β-Cell, a Unique Fuel Sensor. In Nutrients and Cell Signaling (K Dakshinamurti and J.Zempleni, eds)2005

    • Author(s)
      Komatsu M
    • Publisher
      Dekker/CRC Press
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Book] Pancreatic B-Cel, a Unique Fuel Sensor. (K Daksshinamurti and J Zempleni, eds) In Nurients and Cell Signaling2005

    • Author(s)
      Komatsu M
    • Publisher
      Dekker/CRC Press
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Book] Pancreatic β-cell, a unique fuel senser.( Dakshinamurti K, Zempleni J (eds)) Nutients and Cell Signaling.2005

    • Author(s)
      Komatsu M
    • Total Pages
      32
    • Publisher
      Dekker/CRC Press
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Repression of insulin gene transcription by indirect genomic signaling via the estrogen receptor in pancreatic beta cells.2019

    • Author(s)
      Sekido T, Nishio S, Ohkubo Y, Sekido K, Kitahara J, Miyamoto T, Komatsu M
    • Journal Title

      In Vitro Cell Dev Biol Anim

      Volume: 55(4) Issue: 4 Pages: 226-236

    • DOI

      10.1007/s11626-019-00328-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09799
  • [Journal Article] Loss of μ-crystallin causes PPARγ activation and obesity in high-fat diet-fed mice.2019

    • Author(s)
      Ohkubo Y, Sekido T, Nishio SI, Sekido K, Kitahara J, Suzuki S, Komatsu M
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 508(3) Issue: 3 Pages: 914-920

    • DOI

      10.1016/j.bbrc.2018.12.038

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09799
  • [Journal Article] KATP Channel-Independent Pathway and the Glucoreceptor2018

    • Author(s)
      Toru Aizawa, Mitsuhisa Komatsu
    • Journal Title

      Itaru Kojima (Eds): Glucose-sensing Receptor in Pancreatic Beta-cells

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09799
  • [Journal Article] Intracellular free fatty acid upholds β-cell glucose competence: The role of peroxisome proliferator-activated receptor δ and mitochondrial metabolism.2015

    • Author(s)
      Takei M, Komatsu M, Aizawa T
    • Journal Title

      J Diabetes Investig

      Volume: 2 Issue: 2 Pages: 133-136

    • DOI

      10.1111/jdi.12257

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461383
  • [Journal Article] Lactisole inhibits the glucose-sensing receptor T1R3 expressed in mouse pancreatic β-cells.2015

    • Author(s)
      amano K, Nakagawa Y, Ohtsu Y, Li L, Medina J, Tanaka Y, Masuda K, Komatsu M, Kojima I.
    • Journal Title

      Journal of Endocrinology

      Volume: 226 Issue: 1 Pages: 57-66

    • DOI

      10.1530/joe-15-0102

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461383
  • [Journal Article] Efficacy of combination therapy with sitagliptin and low-dose glimepiride in Japanese patients with type 2 diabetes.2014

    • Author(s)
      Ishii H, Ohkubo Y, Takei M, Nishio S, Yamazaki M, Kumagai M, Sato Y, Suzuki S, Aoki Y, Miyamoto T, Kakizawa T, Sakuma T, Komatsu M
    • Journal Title

      J Clin Med Res

      Volume: 2 Pages: 127-132

    • DOI

      10.14740/jocmr1701w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461383
  • [Journal Article] SU薬のポジショニング SU薬はもういらないのか2014

    • Author(s)
      駒津光久
    • Journal Title

      糖尿病診療マスター

      Volume: 12 Pages: 126-161

    • Data Source
      KAKENHI-PROJECT-25461383
  • [Journal Article] ブドウ糖によるインシュリン分泌とインクレチンー生理的意義の理解に向けてー2014

    • Author(s)
      駒津光久、佐藤吉彦、相澤徹
    • Journal Title

      最新医学

      Volume: 69 Pages: 128-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461383
  • [Journal Article] KATP非依存性ブドウ糖応答性シグナルは生理的に重要か?2014

    • Author(s)
      駒津光久
    • Journal Title

      内分泌・糖尿病・代謝内科

      Volume: 39 Pages: 122-127

    • Data Source
      KAKENHI-PROJECT-25461383
  • [Journal Article] A new experimental model of ATP-sensitive K<sup>+</sup> channel-independent insulinotropic action of glucose: a permissive role of cAMP for triggering of insulin release from rat pancreatic &beta;-cells2013

    • Author(s)
      Masahiro Takei
    • Journal Title

      Endocr J

      Volume: 60 Issue: 5 Pages: 599-607

    • DOI

      10.1507/endocrj.EJ12-0388

    • NAID

      10031184527

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591128, KAKENHI-PROJECT-22591853, KAKENHI-PROJECT-23591320, KAKENHI-PROJECT-25461383
  • [Journal Article] Glucose-stimulated insulin secretion: A newer perspective2013

    • Author(s)
      Komatsu M, Takei M, Ishii H, Sato Y.
    • Journal Title

      J Diabetes Invest

      Volume: 4 Issue: 6 Pages: 511-516

    • DOI

      10.1111/jdi.12094

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591128, KAKENHI-PROJECT-25461383
  • [Journal Article] Humoral hypercalcemia associated with gastric carcinoma secreting parathyroid hormone: a case report and review of the literature2013

    • Author(s)
      Nakajima K, Tamai M, Okaniwa S, Nakamura Y, Kobayashi M, Niwa T, Horigome N, Ito N, Suzuki S, Nishio S, Komatsu M.
    • Journal Title

      Endocr J

      Volume: 60 Issue: 5 Pages: 557-562

    • DOI

      10.1507/endocrj.EJ12-0406

    • NAID

      10031184522

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Journal Article] A new experimental model of ATP-sensitive K+channel-independent insulinotropic action of glucose: a permissive role of cAMP for triggering of insulin release from rat pancreatic beta-cells.2013

    • Author(s)
      Takei M, Dezaki K, Ishii H, Nishio SI, Sato Y, Suzuki S, Yada T, Komatsu M
    • Journal Title

      Endocrine journal.

      Volume: 60 Pages: 599-607

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591128
  • [Journal Article] Possible Roles of the AP-1 Site in the Cytosolic T3 Binding Protein Promoter and Insights into its Physiological Significance.2013

    • Author(s)
      Suzuki S, Nishio SI, Ishii H, Sekido T, Takeshige K,Ohkubo Y, Hiwatashi D, Takeda T, Komatsu M.
    • Journal Title

      Horm Metab Res.

      Volume: Mar 18. Issue: 07 Pages: 501-506

    • DOI

      10.1055/s-0033-1337933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Journal Article] Pituitary resistance to thyroid hormones : pathophysiology and therapeutic options2012

    • Author(s)
      Suzuki S, Nishio S, Takeda T, Komatsu M
    • Journal Title

      Thyroid Res

      Volume: 5(1) Issue: 1 Pages: 1-1

    • DOI

      10.1186/1756-6614-5-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591853, KAKENHI-PROJECT-23591349
  • [Journal Article] Bariatric surgery on type 2 dizbetes mellitus patients in Japan. Shinshu2011

    • Author(s)
      Mori J, Sato Y, Ishii H, Komatsu M.
    • Journal Title

      Med J

      Volume: 59(4) Pages: 273-279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591128
  • [Journal Article] Pituitary resistance to thyroid hormones : pathophysiology and therapeutic options2011

    • Author(s)
      Suzuki S, Shigematsu S, Inaba H, Takei M, Takeda T, Komatsu M
    • Journal Title

      Endocrine

      Volume: 40(3) Issue: 3 Pages: 366-371

    • DOI

      10.1007/s12020-011-9538-2

    • Data Source
      KAKENHI-PROJECT-22591853
  • [Journal Article] Glucose-incretin interaction revisited.2011

    • Author(s)
      Ishii H, Sato Y, Takei M, Nishio S, Komatsu M.
    • Journal Title

      Endocr J

      Volume: 58(7) Pages: 519-525

    • NAID

      10029589169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591128
  • [Journal Article] Glucose-incretin interaction revisited [Review]2011

    • Author(s)
      Ishii H, Sato Y, Takei M, Nishio S, Komatsu M
    • Journal Title

      Endocr J

      Volume: 58 Issue: 7 Pages: 519-525

    • DOI

      10.1507/endocrj.EJ11-0064

    • NAID

      10029589169

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591128, KAKENHI-PROJECT-22591853
  • [Journal Article] 機能的膵β細胞量を標的としたあらたな糖尿病治療-GLP-1治療の展望2010

    • Author(s)
      駒津光久
    • Journal Title

      International Review of Diabetes

      Volume: 2 Pages: 24-25

    • Data Source
      KAKENHI-PROJECT-21591128
  • [Journal Article] Transient polyuria related to central diabetes insipidus caused by lymphocytic infundibulo‐neurohypophysitis in a patient treated for Graves'disease2010

    • Author(s)
      Yamazaki M, Sato A, Nishio S, Uehara T, Komatsu M
    • Journal Title

      Intern Med

      Volume: 49 Pages: 1885-1890

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591128
  • [Journal Article] closed-loopとopen-loopによる血糖制御2010

    • Author(s)
      駒津光久
    • Journal Title

      内分泌・糖尿病・代謝内科

      Volume: 30 Pages: 591-595

    • NAID

      40017666413

    • Data Source
      KAKENHI-PROJECT-21591128
  • [Journal Article] Distinct Clinical Courses in Type 1 Diabetes Mellitus Induced by Peg-interferon-alpha Treatment for Chronic Hepatitis C2010

    • Author(s)
      Yamazaki M, Sato A, Takeda T, Komatsu M
    • Journal Title

      Intern Med 49

      Pages: 403-407

    • NAID

      130000251685

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591128
  • [Journal Article] C10sed-loopとopen-loopによる血糖制御2010

    • Author(s)
      駒津光久
    • Journal Title

      内分泌等幼猫代謝内科

      Volume: 30 Pages: 591-595

    • Data Source
      KAKENHI-PROJECT-22591853
  • [Journal Article] Transient polyuria related to central diabetes insipidus caused by lymphocytic infundibulo-neurohypophysitis in a patient treated for Graves' disease.2010

    • Author(s)
      Yamazaki M, Sato A, Nishio S,Ue hara T, Komatsu M.
    • Journal Title

      Intern Med.

      Volume: 49(17) Pages: 1885-1890

    • NAID

      130000336870

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Journal Article] 機能的膵β細胞量を標的としたあらたな糖尿病治療一GLPI治療の展望一2010

    • Author(s)
      駒津光久
    • Journal Title

      International Review of Diabetes

      Volume: 2 Pages: 24-25

    • Data Source
      KAKENHI-PROJECT-22591853
  • [Journal Article] Enhancement of the incretin pathway in response to bariatric surgery is important for restoration of beta cell function2009

    • Author(s)
      Komatsu M, Aizawa T
    • Journal Title

      Diabetologia 52

      Pages: 374-375

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591128
  • [Journal Article] Acute and chronic treatment of L-isoleucine ameliorates glucose metabolism inglucose-intolerant and diabetic mice.2008

    • Author(s)
      Ikehara O, Kawasaki N, Maezono K, Komatsu M, Konishi A
    • Journal Title

      Biol Pharm Bull 31

      Pages: 469-472

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Acute and chronic treatment of L-isoleucine ameliorates glucose metabolism in glucose-intolerant and diabetic mice.2008

    • Author(s)
      Ikehara O, Kawasaki N, Maezono K, Komatsu M, Konishi A
    • Journal Title

      Biol Pharm Bull 31

      Pages: 469-472

    • NAID

      110006623076

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Acute and chronic treatment of L-isoleucine ameliorates glucose metabolism in glucose-intolerant and diabetic mice2008

    • Author(s)
      Ikehara, 0., Kawasaki, N., Maezono, K., Komatsu, M., Konishi, A
    • Journal Title

      Biol Pharm Bull 31

      Pages: 469-472

    • NAID

      110006623076

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Adiponectin Inversely Correlates with High Sensitive C-reactive Protein and Triglycerides, but not with Insulin Sensitivity, in Apparently Healthy Japanese Men2007

    • Author(s)
      Komatsu, M., Ohfusa, H., Aizawa, T., Hashizume, K
    • Journal Title

      Endocr J 54

      Pages: 553-558

    • NAID

      10019809309

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Adiponectin Inversely Correlates with High Sensitive C-reactive Protein and Triglycerides, but not with Insulin Sensitivity, in Apparently Healthy Japanese Men.2007

    • Author(s)
      Komatsu M, Ohfusa K, Aizawa T, Hashizume K
    • Journal Title

      Endocr J In press

    • NAID

      10019809309

    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Development, worsening, and improvement of diabetic microangiopathy in older people : six-year prospective study of patients under intensive diabetes control.2007

    • Author(s)
      Katakura M, Naka M, Kondo T, Komatsu M et al.
    • Journal Title

      J Am Geriatr Soc 55

      Pages: 541-547

    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Normal mortality in the elderly with diabetes under strict glycemic and blood pressure control: Outcome of 6-year prospective study.2007

    • Author(s)
      Katakura M, Naka M, Kondo T, Komatsu M, Yamauchi K, Hashizume K, Aizawa T
    • Journal Title

      Diabetes Res Clin Pract 78

      Pages: 108-114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Adiponectin Inversely Correlates with High Sensitive C-reactive Protein and Triglycerides, but not with Insulin Sensitivity, in Apparently Healthy Japanese Men.2007

    • Author(s)
      Komatsu M, Ohfusa H, Aizawa T, Hashizume K
    • Journal Title

      Endocr J 54

      Pages: 553-558

    • NAID

      10019809309

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Normal mortality in the elderly with diabetes under strict glycemic and blood pressure control : Outcome of 6-year prospective study.2007

    • Author(s)
      Katakura M, Naka M, Kondo T, Komatsu M et al.
    • Journal Title

      Diabetes Res Clin Pract In press

    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Development, worsening, and improvement of diabetic microangiopathy in older people: six-year prospective study of patients under intensive diabetes control.2007

    • Author(s)
      Katakura M, Naka M, Kondo T, Komatsu M, Yamauchi K, Hashizume K, Aizawa T
    • Journal Title

      J Am Geriatr Soc 55

      Pages: 541-547

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Effect of Methimazole Treatment for 2 Years on Circulating lL-4, lgE, TBll, and TSAb in Patients with Hyperthayroid Graves' Disease.2006

    • Author(s)
      Yamada T, Komiya I, Miyahara Y, Komatsu M et al.
    • Journal Title

      Endocr J 53

      Pages: 783-788

    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Rab27a : a new face in beta cell metabolism-secretion Coupling.2005

    • Author(s)
      Aizawa T, Komatsu M.
    • Journal Title

      J Clin Invest 115

      Pages: 227-230

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Journal Article] Development, progression, and regression of microalbuminuria in Japanese patients with type 2 diabetes under tight glycemic and blood pressure control: the Kashiwa study.2005

    • Author(s)
      Yamada T, Komatsu M et al.
    • Journal Title

      Diabetes Care 28

      Pages: 2733-2738

    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Rab27a : a new face in beta cell metabolism-secretion coupling2005

    • Author(s)
      Aizawa, T., Komatsu, M
    • Journal Title

      J Clin Invest 115

      Pages: 227-230

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Rab27a: a new face in beta cell metabolism-secretion coupling.2005

    • Author(s)
      Aizawa T, Komatsu M
    • Journal Title

      J Clin Invest 115

      Pages: 227-230

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Pancreatic β-cell, a Unique Fuel Sensor.2005

    • Author(s)
      Komatsu M.
    • Journal Title

      Nutrient and Cell Signaling (K Daksshinamurti, J Zempleni.eds) (Dekker/CRC Press)

      Pages: 533-564

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Journal Article] Rab27a : a new face in beta cell metabolism-secretion coupling.2005

    • Author(s)
      Aizawa T, Komatsu M
    • Journal Title

      Journal of Clinical Investigation 115

      Pages: 227-230

    • Data Source
      KAKENHI-PROJECT-17590956
  • [Journal Article] Rab27a : a new face in beta cell metabolism-secretion coupling.2005

    • Author(s)
      Aizawa T, Komatsu M
    • Journal Title

      J Clin Invest 115

      Pages: 227-230

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Journal Article] Primacy of beta-cell dysfunction in the development of hyperglycemia : A study in the Japanese general population.2004

    • Author(s)
      Katakura M, Komatsu M et al.
    • Journal Title

      Metabolism 53

      Pages: 949-953

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Journal Article] Strong inverse correlation between adiponectin level and Heart rate-corrected QT interval in apparently healthy population.2004

    • Author(s)
      Komatsu M et al.
    • Journal Title

      Diabetes Care 27

      Pages: 1237-1238

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Journal Article] Strong inverse correlation between adiponectin level and heart rate-corected QT interval in apparently healthy population.2004

    • Author(s)
      Komatsu M et al.
    • Journal Title

      Diabetes Care 27

      Pages: 1237-1238

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Journal Article] Strong inverse correlation between adiponectin level and heart rate-corrected QT interval in apparently healthy population.2004

    • Author(s)
      Komatsu M et al.
    • Journal Title

      Diabetes Care 27

      Pages: 1237-1238

    • Data Source
      KAKENHI-PROJECT-13671151
  • [Journal Article] The retinoic acid-responsive proline-rich protein is identified in promyeloleukemic HL-60 cells.2004

    • Author(s)
      Inagaki T, Suzuki S, Miyamoto T, Takeda T, Yamashita K, Komatsu A, Yamauchi K, Hashizume K.
    • Journal Title

      J Biol Chem 278

      Pages: 51685-51692

    • Data Source
      KAKENHI-PROJECT-15590972
  • [Journal Article] Primacy of beta-cell dysfunction in the Development of hyperglycemia : A study in the Japanese general population2004

    • Author(s)
      Katakura M, Komatsu M et al.
    • Journal Title

      Metabolism 53

      Pages: 949-953

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Journal Article] Presence of functional domains in NADPH-dependent cytosolic 3,5,3'-Triiodo-L-thyronine (T3)-binding protein (p38CTBP) molecule : analyses with deletion mutants.2004

    • Author(s)
      Suzuki S, Mori JI, Kobayashi M, Inagaki T, Komatsu A, Yamashita K, Takeda T, Miyamoto T, Ichikawa K, Hashizume K.
    • Journal Title

      Horm Metab Res 35

      Pages: 577-582

    • Data Source
      KAKENHI-PROJECT-15590972
  • [Journal Article] Nutrient modulation of palmitoylated 24-kDa Protein in rat pancreatic islets.2003

    • Author(s)
      Yamada S, Komatsu M et al.
    • Journal Title

      Endocrinology 144

      Pages: 5232-5241

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Journal Article] Nutrient modulation of palmitoylated 24-kDa protein in rat pancreatic islets.2003

    • Author(s)
      Yamada S, Komatsu M et al.
    • Journal Title

      Endocrinology 144

      Pages: 5232-5241

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Journal Article] Time-dependent potentiation of the β-cell is a Ca2+-independent phenomenon.2002

    • Author(s)
      Yamada S, Komatsu M et al.
    • Journal Title

      J Endocrinology 172

      Pages: 345-354

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Journal Article] Time-dependent potentiation of the B-cell is a Ca^<2+>-independent phenomenon.2002

    • Author(s)
      Yamada S, Komatsu M et al.
    • Journal Title

      J Endocrinology 172

      Pages: 345-354

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Journal Article] Triggering of insulin release by a combination of cAMP signal and nutrients, an ATP sensitive K^+channel-independent phenomenon.2002

    • Author(s)
      Komatsu M et al.
    • Journal Title

      Diabetes

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Journal Article] Triggering of insulin release by a combination of cAMP signal and nutrients, an ATP sensitive K+ channel-independent phenomenon.2002

    • Author(s)
      Komatsu M et al.
    • Journal Title

      Diabetes 51

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13671151
  • [Presentation] マウスにおける甲状腺ホルモン結合蛋白(CRYM)の糖代謝に対する影響2016

    • Author(s)
      関戸貴志、大久保洋輔、竹重恵子、北原順一郎、西尾真一、鈴木悟、駒津光久
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      京都 国立国際会議場
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-16K09799
  • [Presentation] Repression of Insulin Gene Transcription by Estrogen Receptor in Pancreatic Beta Cells2015

    • Author(s)
      Keiko Sekido, Yohusuke Ohkubo, Takashi Sekido, Shin-ichi Nishio, Mitsuhisa Komatsu
    • Organizer
      American Diabetes Association's (ADA) 75th Scientific Sessions in Boston
    • Place of Presentation
      ボストン、USA
    • Year and Date
      2015-06-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461383
  • [Presentation] Tri-iodothyronine acts as prospective factor against hyperglycemia mainly via thyroid hormone receptor β.2015

    • Author(s)
      Yohusuke Ohkubo, Takashi Sekido, Keiko Sekido, Shin-ichi Nishio, Mitsuhisa Komatsu
    • Organizer
      American Diabetes Association's (ADA) 75th Scientific Sessions in Boston
    • Place of Presentation
      ボストン、USA
    • Year and Date
      2015-06-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461383
  • [Presentation] ブドウ糖、プロテインキナーゼC、cAMPはCa2+非依存性にreadily releasable poolを増加させる2014

    • Author(s)
      石井宏明、武井真大、関戸貴志、西尾真一、山崎雅則、佐藤吉彦、駒津光久
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪市
    • Data Source
      KAKENHI-PROJECT-25461383
  • [Presentation] 糖尿病、肥満症の患者にエキセナチドを導入して著効した3例2012

    • Author(s)
      西尾真一、石井宏明、武井真大, 山崎雅則、鈴木悟、駒津光久
    • Organizer
      日本糖尿病学会関東甲信越地方会
    • Place of Presentation
      東京
    • Year and Date
      2012-01-21
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] Combinationtherapy with low dose glimepiride and sitagliptin is reasonably effective for poorly controlled type 2 diabetes patients2012

    • Author(s)
      Ishii H, Takei M, Nisio S, Sato Y, Suzuki S, Komatsu M.
    • Organizer
      第48回ヨーロッパ糖尿病学会
    • Place of Presentation
      ベルリン、ドイツ
    • Year and Date
      2012-10-01
    • Data Source
      KAKENHI-PROJECT-21591128
  • [Presentation] TRβはPAX6、BETA2を介してインスリン転写活性を増強する2011

    • Author(s)
      西尾真一、石井宏明、武井真大, 四宮健、宮本高秀、武田貞二、鈴木悟、駒津光久
    • Organizer
      日本甲状腺学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-11-22
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] Acute triggering of insulin release concomitant with a decrease in cytosolic free Ca^ concentration by a combination of glucose and cAMP.2011

    • Author(s)
      Takei M, Ishii H, Nisio S, Sato Y, Komatsu M.
    • Organizer
      第47回ヨーロッパ糖尿病学会
    • Place of Presentation
      リスボン、ポルトガル
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-21591128
  • [Presentation] TRβはPAX6、BETA2を介してインスリン転写活性を増強する2011

    • Author(s)
      石井宏明、西尾真一、武井真大, 四宮健、宮本高秀、鈴木悟、駒津光久
    • Organizer
      日本内分泌学会
    • Place of Presentation
      神戸
    • Year and Date
      2011-04-22
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] ERαはPDX-1、BETA2を介してインスリン転写活性を抑制する2011

    • Author(s)
      西尾真一、石井宏明、武井真大、鈴木悟、駒津光久
    • Organizer
      日本糖尿病学会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] ゼブラフィッシュレプチン受容体OB-Rbは筋形成に必要である2011

    • Author(s)
      西尾真一、武井真大、石井宏明、鈴木悟、駒津光久、Vincent Laudet
    • Organizer
      日本内分泌学会
    • Place of Presentation
      神戸
    • Year and Date
      2011-04-21
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] 糖尿病、肥満症の患者にエキセナチドを導入して著効した2例2011

    • Author(s)
      西尾真一、石井宏明、武井真大, 佐藤亜位、山崎雅則、駒津光久
    • Organizer
      日本肥満学会
    • Place of Presentation
      淡路
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] Acute triggering of insulin release concomitant with a decrease in cytosolic free Ca2+concentration by a combination of glucose and cAMP2011

    • Author(s)
      M.Takei, H.Ishii, S Nisio, Y.Sato, M.Komatsu
    • Organizer
      第47回欧州糖尿病学会
    • Place of Presentation
      リスボン(ポルトガル)
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-21591128
  • [Presentation] The Phytoestrogen Genistein Affects Zebrafish Development through Two Different Pathways2011

    • Author(s)
      Shin-ichi Nishio, Sana Sassi-Messai, Yann Gibert, Hiroaki Ish-i, Masahiro Takei, Satoru Suzuki, Mitsuhisa Komatsu, Patrick Balaguer, Laudet Vincent
    • Organizer
      日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] ERαはPDX-1、BETA2を介してインスリン転写活性を抑制する2011

    • Author(s)
      武井真大、西尾真一、四宮健、石井宏明、鈴木悟、駒津光久
    • Organizer
      日本内分泌学会
    • Place of Presentation
      神戸
    • Year and Date
      2011-04-21
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] ゼブラフィッシュレプチン受容体OB-Rbは筋形成に必要である2011

    • Author(s)
      西尾真一、石井宏明、武井真大、駒津光久、Vincent Laudet
    • Organizer
      日本肥満学会
    • Place of Presentation
      淡路
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] SHPはPDX-1プロモーター転写活性を抑制する2011

    • Author(s)
      四宮健、西尾真一、石井宏明、武井真大、柿澤供子、宮本高秀, 鈴木悟、駒津光久
    • Organizer
      日本内分泌学会
    • Place of Presentation
      神戸
    • Year and Date
      2011-04-23
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] Leptin receptor homolog in zebrafish controls morphogenetic movements duringgastrulation and is involved in somite formation.2010

    • Author(s)
      西尾真一,石井宏明,武井真大,鈴木悟,駒津光久、ローデヴァンサン
    • Organizer
      日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] Quantitative assessment of diabetic neuropathy using a newly developed device, Pain Vision.2007

    • Author(s)
      Komatsu M, Hiramatsu K, Hashizume K
    • Organizer
      3rd Scientific Meeting of Asia-Pacific Diabetes and Obesity Study Group
    • Place of Presentation
      Taizhou, China
    • Year and Date
      2007-08-26
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Presentation] Adiponectin inversely correlates with triglyceride and high-sensitivity C-reactive protein butnot with insulin or insulin resistance index in Japanese men.2006

    • Author(s)
      Komatsu M, Ohfusa H, Aizawa T, Hashizume K
    • Organizer
      19th World Diabetes Congress
    • Place of Presentation
      Cape Town, South Africa
    • Year and Date
      2006-12-05
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Presentation] Adiponectin inversely correlates with triglyceride and high-sensitivity C-reactive protein but not with insulin or insulin resistance index in Japanese men2006

    • Author(s)
      Komatsu, M., Ohfusa, H., Aizawa, T., Hashizume, K
    • Organizer
      19th World Diabetes Congress
    • Place of Presentation
      Cape Town, South Africa
    • Year and Date
      2006-12-05
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590956
  • [Presentation] プレドニゾロン(PSL)が著効した後天性high density lipoprotein cholesterol (HDL-C)欠損症の1例

    • Author(s)
      西尾真一、日高宏哉、有賀雅和、石井宏明、武井真大、山崎雅則、鈴木悟、駒津光久
    • Organizer
      日本内分泌学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] 母子共にDUOX2遺伝子へテロ接合変異、TSB-Ab 陽性で母親が甲状腺機能低下症、児が甲状腺機能低下症および甲状腺腫大を来した一例

    • Author(s)
      西尾真一、阿部清美、大平哲史、平林佳奈枝、石井宏明、山崎雅則、櫻井晃洋、鈴木悟、長谷川奉延、駒津光久
    • Organizer
      日本甲状腺学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] Triiodothyronine acts as protective factor against hyperglycemia mainly via thyroid hormone receptor beta

    • Author(s)
      Ohkubo Y, Sekido T, Sekido K, Suzuki S, Sato Y, Nishio S, Komatsu M
    • Organizer
      75th the American Diabetes Association's scientific sessions
    • Place of Presentation
      Boston, USA
    • Year and Date
      2015-06-05 – 2015-06-09
    • Data Source
      KAKENHI-PROJECT-25461383
  • [Presentation] The activation of rat insulin gene II transcription by thyroid hormone receptor beta in pancreatic beta cells.

    • Author(s)
      Nishio S, Ishi-i H, Suzuki S, Komatsu M
    • Organizer
      日本分子生物学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] 二相性インスリンアナログ製剤(BIAsp)3回投与法の有効性・安全性に関する研究:50BIAspと70BIAspの比較

    • Author(s)
      西尾真一、武田貞二、佐藤亜位、鈴木悟、駒津光久
    • Organizer
      日本糖尿病学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] ペグミソマントによりコントロール改善した先端巨大症の一例

    • Author(s)
      西尾真一、山崎雅則、武田貞二、鈴木悟、駒津光久
    • Organizer
      日本内分泌学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22591853
  • [Presentation] The Phytoestrogen Genistein Affects Zebrafish Development through Two Different Pathways.

    • Author(s)
      Nishio S, Sassi-Messai S, Gibert Y, Ish-I H, Takei M, Suzuki S, Komatsu M, Balaguer P, Laudet V
    • Organizer
      日本内分泌学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22591853
  • 1.  KABURAGI Yasushi (40342927)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  NODA Mitsuhiko (90237850)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  NISHIO Shin-ichi (30467146)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 25 results
  • 4.  AIZAWA Toru (90150896)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  SUZUKI Satoru (30222061)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  YAMAUCHI Keishi (30191191)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  MIYAMOTO Takahide (20192768)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  小島 至 (60143492)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  大久保 洋輔 (70793925)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  相沢 徹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 13 results

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