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Imaizumi Tadaatsu  今泉 忠淳

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IMAIZUMI Tadaatsu  今泉 忠淳

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Researcher Number 90232602
Other IDs
Affiliation (Current) 2025: 弘前大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help 2016 – 2024: 弘前大学, 医学研究科, 教授
2013 – 2015: 弘前大学, 大学院医学研究科, 教授
2012 – 2015: 弘前大学, 医学(系)研究科(研究院), 教授
2014: 弘前大学, 医学研究科, 教授
2012: 弘前大学, 大学院・医学研究科, 教授 … More
2011: 弘前大学, 医学(系)研究科(研究院), 助教
2011: 弘前大学, 医学研究科, 助教
2008 – 2011: Hirosaki University, 大学院・医学研究科, 助教
1999 – 2006: 弘前大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Kidney internal medicine / 膠原病・アレルギー・感染症内科学 / Respiratory organ internal medicine
Except Principal Investigator
Basic Section 55030:Cardiovascular surgery-related / Pediatrics / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Immunology / Neurology / Public health/Health science … More / Kidney internal medicine / Hematology / Obstetrics and gynecology / Human pathology / Cerebral neurosurgery Less
Keywords
Principal Investigator
TLR3 / CCL5 / RIG-I / メサンギウム細胞 / IFN-γ / poly IC / inflammation / 血管内皮細胞 / 慢性腎臓病 / ISGs … More / endothelial cells / 糸球体血管内皮細胞 / IFN-beta / innate immunity / TLR / IFN / ISG / microRNA-155 / TNF-α / microRNA / RIG-1 / Th1 / ISG20 / DEC2 / IFN-β / 慢性炎症 / 細胞質RNA受容体 / MDA5 / ループス腎炎 / リウマチ / 15-deoxy-Δ^<12,14>-prostaglandin J_2 / 抗ウイルス応答 / STAT1 / 炎症性サイトカイン / lipopolysaccharide / Lsiteria monocytgogenes / IP-10 / influenza A virus / psoriasis / lupus nephritis / atherosclerosis / RANTES / Hepatitis C virus / HSP90 / CTLD / 炎症性疾患 / 感染症 / 免疫応答 / Toll 様受容体 … More
Except Principal Investigator
自然免疫 / 大動脈弁狭窄症 / 異所性石灰化 / Toll-like receptor 3 / 大動脈弁石灰化 / 大動脈弁異所性石灰化 / テネイシンX / 大動脈弁間質細胞 / Toll様受容体3 / 腎糸球体内皮細胞 / 動脈硬化 / ネフローゼ症候群 / ポドサイト / TLR3 / CXCL1 / Interferon-β / 炎症性ケモカイン / メサンギウム細胞 / 培養ヒトメサンギウム細胞 / シンフィリン / calcification / aortic valve / 核内受容体 / valve calcification / 腎炎 / Toll様受容体 / 炎症性ケモカイン・サイトカイン / 腎構成細胞 / Toll様受容体 3 / 腎尿細管上皮細胞 / 血管内皮増殖因子受容体2 / 薬物治療 / Valve calcification / VEGFR2 / 薬物療法 / CD34陰性細胞 / Wnt5a / メノキナン-4 / 重症大動脈弁狭窄症 / 症候性大動脈弁狭窄症 / 黄連解毒湯 / マトリックスGlaタンパク / プレグナンX受容体 / 異物受容体 / 大動脈弁 / マトリックスGlaタンパク質 / IL6 / Toll like receptor 3 / 細胞骨格 / 脂質ラフト / Raftlin / リツキシマブ / SMPDL3b / 小児特発性ネフローゼ症候群 / 小児腎・泌尿器学 / クラリスロマイシン / ISG / クロロキン / Cylindromatosis / インターロイキン6 / 抗マラリア薬 / 糸球体腎炎 / 慢性腎臓病 / Toll様受容体3 / 培養ヒト糸球体上皮細胞 / Ubiquitin-like protein / Synucleinopathy / Multiple system atrophy / Lewy body / Parkinson's disease / Beta-synuclein / Alpha-synuclein / ユビキチン / NEDD8 / ユビキチン様蛋白 / シヌクレイノパチー / 多系統萎縮症 / レビー小体 / パーキンソン病 / βシヌクレイン / αシヌクレイン / cancer / vascular diseases / PAF acetylhydrolase deficiency / oxidized phospholipid / PAF acetylhydrolase / platelet-activating factor (PAF) / 血小板活性化因子アセチルヒドロラーゼ / 喫煙 / PAFアセチルヒドロラーゼ欠損症 / がん / 血管障害 / 酸化リン脂質 / PAFアセチルヒドロラーゼ / 血小板活性化因子(PAF) / 非翻訳領域 / importin / IFN / インポーチン / Importin / インターフェロン / 免疫学 / IFN / 感染症 / 産婦人科 / CD80 / 糸球体上皮細胞 / mizoribine / CCL5 / MCP-1 / Mx1 / toll-like receptor 3 / lupus nephritis / pseudoviral immunity / human mesangial cells / ISG15 / 腎炎症候群 / Tumor microebvironment / Type 1 interferon / EBER / BRLF1 / BZLF1 / CCL20 / interferon / innate immunity / cytotoxic T cell / regulatory T cell / Interferon / IRF3 / RIG-I / Epstein Barr virus / Hodgkin lymphoma / RLRs / 細胞内小器官 / 細胞小器官 / ウイルスセンサー / RLR / 抗ウイルスシグナル / ミトコンドリア / 細胞生物学 / ウイルス学 / interferon-β / CC chemokine ligand5 / Toll-like receptor3 / 培養ヒトメサンギム細胞 / Interferon stimulated gene 20 / polyinosinic-polycytidylic acid / Retinoic acid-inducible gene-I / レチノイン酸誘導遺伝子アイ / 小児腎・泌尿器科学 / 泌尿器科学 / 小児腎 / 転写後調節 / IFN-ε / 女性生殖器 / 免疫応答 / 婦人科免疫学 / 婦人科学 / 封入体 / プロテオーム / 蛋白質 / 脳神経疾患 / 低酸素 / 脳出血 / 脳血管障害 / グリア / オピオイド / プラスミノーゲン / ヘモルフィン / アストロサイト / シグナル伝達機構 / プロテアゾーム / 血管平滑筋細胞 / β-シヌクレイン / インターロイキン-1 / 血管内皮細胞 / MAP kinase / アストログリア / α-シヌクレイン Less
  • Research Projects

    (24 results)
  • Research Products

    (189 results)
  • Co-Researchers

    (37 People)
  •  the transformation of aortic valve endothelial cells induced acceleration of aortic valve calcification and its mechanism

    • Principal Investigator
      于 在強
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Hirosaki University
  •  大動脈弁異所性石灰化に関わる核内受容体ファミリーの解析と新規治療の構築について

    • Principal Investigator
      瀬谷 和彦
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Hirosaki University
  •  Inflammatory pathways via innate immunity in resident renal cells and their regulation against the development of kidney injury

    • Principal Investigator
      田中 完
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Hirosaki University
  •  The role and mechanism of VEGFR2 on aortic valve calcification

    • Principal Investigator
      Yu Zaiqiang
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Hirosaki University
  •  Elucidation of the mechanism of pregnane X receptor-mediated aortic valve ectopic calcification and demonstration of its pathophysiological significance

    • Principal Investigator
      Daitoku Kazuyuki
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Hirosaki University
  •  小児特発性ネフローゼ症候群におけるSMPDL-3bの意義の解明

    • Principal Investigator
      渡邊 祥二郎
    • Project Period (FY)
      2019 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Ehime University
      Hirosaki University
  •  Demonstration and mechanism elucidation of the inhibition of aortic valve calcification by controlling expression of extracellular matrix protein

    • Principal Investigator
      Seya Kazuhiko
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Hirosaki University
  •  Molecular mechanisms of chronic renal diseases by Interferon-stimulated genes (ISGs)Principal Investigator

    • Principal Investigator
      Imaizumi Tadaatsu
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Hirosaki University
  •  Glomerular inflammation induced by innate immune reaction in residual glomerular cells and future therapeutic strategy for CKD

    • Principal Investigator
      Tanaka Hiroshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Hirosaki University
  •  Study on local regulation of gene expression of female reproductive-specific IFN

    • Principal Investigator
      MATSUMIYA TOMOH
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Hirosaki University
  •  Role of mesangial RNA recognition receptors in innate immunity and chronic renal diseasesPrincipal Investigator

    • Principal Investigator
      Imaizumi Tadaatsu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Hirosaki University
  •  Mesangial viral and psuedoviral immunity: possible involvement in the pathogenesis of glomerulonephritis

    • Principal Investigator
      Tanaka Hiroshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Hirosaki University
  •  The regulatory mechanisms of the CD80 expression in the podocytes.

    • Principal Investigator
      SHIMADA Michiko
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Hirosaki University
  •  Elucidation of innate immunity pathway for the development of a novel therapy of Hodgkin lymphoma

    • Principal Investigator
      WADA Ryuichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Nippon Medical School
      Hirosaki University
  •  Elucidation of interorganelle network in RLRs-mediated innate immunity

    • Principal Investigator
      MATSUMIYA Tomoh
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Hirosaki University
  •  Implication of the expression of retinoic acid-inducible gene-I in human glomerulonephritis

    • Principal Investigator
      TANAKA Hiroshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Hirosaki University
  •  Development of therapeutic strategies for RA targeting TNF-α-inducible RNA receptors in cytoplasmPrincipal Investigator

    • Principal Investigator
      IMAIZUMI Tadaatsu
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Hirosaki University
  •  Identification of NUB1-interacting proteins in alpha-synucleinopathy

    • Principal Investigator
      TANJI Kunikazu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Hirosaki University
  •  Study on regulation of gene expression of a novel female reproductive organ-specific Type I interferon

    • Principal Investigator
      MATSUMIYA Tomoh
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Hirosaki University
  •  Role of a new Toll-like receptor-related signaling molecule in immunereactions in lung and airwayPrincipal Investigator

    • Principal Investigator
      IMAIZUMI Tadaatsu, 吉田 秀見
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Hirosaki University
  •  脳血管障害におけるオピオイドペプチドの新しい働き:ヘモルフィンの関与

    • Principal Investigator
      吉田 秀見
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Hirosaki University
  •  Molecular pathomechanisms in alpha-synucleinopathis

    • Principal Investigator
      WAKABAYASHI Koichi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Hirosaki University
  •  パーキンソン病におけるα-シヌクレイン蓄積機序に関する研究

    • Principal Investigator
      SATOH Kei
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Hirosaki University
  •  Smoking-induced generation of oxidized phospholipids and the effect of deficiency of hydrolyzing enzyme for oxidatively modified phospholipids : role of the enzyme deficiency in carcinogenesis and vascular injury.

    • Principal Investigator
      SATOH Kei
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Public health/Health science
    • Research Institution
      Hirosaki University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] Implication of regional activation of toll-like receptor 3/interferon-β signaling in human mesangial cells: possible involvement in the pathogenesis of lupus nephritis. In Autoimmune Diseases2015

    • Author(s)
      Tanaka H, Tsuruga K, Imaizumi T.
    • Publisher
      InTec Open Access Publisher, Rijeka, Croatia.
    • Data Source
      KAKENHI-PROJECT-25461615
  • [Book] In : Genes and Autoimmunity - Intracellular signaling and microbiome contribution2013

    • Author(s)
      Tanaka H, Imaizumi T
    • Publisher
      Toll-like receptor 3 and retinoic acid-inducible gene-I implicated to the pathogenesis of autoimmune renal diseases
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Book] Toll-like receptor 3 and retinoic acid-inducible gene-I implicated to the pathogenesis of autoimmune renal diseases. In: Genes and Autoimmunity – Intracellular signaling and microbiome contribution. Stanilova SA Eds.2013

    • Author(s)
      Tanaka H, Imaizumi T
    • Total Pages
      267
    • Publisher
      InTec Open Access Publisher, Rijeka, Croatia
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Book] Toll-like receptor 3 and retinoic acid-inducible gene-I implicated to the pathogenesis of autoimmune renal diseases. In: Genes and Autoimmunity - Intracellular signaling and microbiome contribution, Stanilova SA Eds.2013

    • Author(s)
      Tanaka H, Imaizumi T
    • Total Pages
      276
    • Publisher
      InTec Open Access Publisher
    • Data Source
      KAKENHI-PROJECT-25461615
  • [Book] Treatment of pediatric-onset lupus nephritis : New option of less cytotoxic immunosupp ressive therapy. In Autoimmune Disorders : Current concepts & advances from bedside to mechanistic insights, Fang-Ping Huang Eds2011

    • Author(s)
      Tanaka H, Imaizumi T
    • Publisher
      InTec Open Access Publisher, Rijeka, Croatia
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Book] In Autoimmune Disorders : Current concepts & advances from bedside to mechanistic insights2011

    • Author(s)
      Tanaka H, Imaizumi T
    • Publisher
      Treatment of pediatric-onset lupus nephritis : New option of less cytotoxic immunosuppressive therapy
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Journal Article] Resiquimod Induces C-C Motif Chemokine Ligand 2 Via Nuclear Factor-Kappa B in SH-SY5Y Human Neuroblastoma Cells2024

    • Author(s)
      Kaizuka Masatoshi、Kawaguchi Shogo、Tatsuta Tetsuya、Tachizaki Mayuki、Kobori Yuri、Tanaka Yusuke、Seya Kazuhiko、Matsumiya Tomoh、Imaizumi Tadaatsu、Sakuraba Hirotake
    • Journal Title

      NeuroMolecular Medicine

      Volume: 26 Issue: 1 Pages: 16-16

    • DOI

      10.1007/s12017-024-08782-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K08064
  • [Journal Article] Possible involvement of DExD/H box helicase 60 in synovial inflammation of rheumatoid arthritis: role of toll-like receptor 3 signaling2024

    • Author(s)
      Nakamura Yuzuru、Ishibashi Hikaru Kristi、Saruga Tatsuro、Imaizumi Tadaatsu、Kurose Akira、Tachizaki Mayuki、Kawaguchi Shogo、Seya Kazuhiko、Sasaki Eiji、Ishibashi Yasuyuki
    • Journal Title

      Molecular Biology Reports

      Volume: 51 Issue: 1 Pages: 131-131

    • DOI

      10.1007/s11033-023-09063-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09393, KAKENHI-PROJECT-23K08064
  • [Journal Article] The inhibitory effect of DIF-3 on polyinosinic?polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells2024

    • Author(s)
      Araya Ryusei、Men Shihu、Uekusa Yoshinori、Yu Zaiqiang、Kikuchi Haruhisa、Daitoku Kazuyuki、Minakawa Masahito、Kawaguchi Shogo、Furukawa Ken-Ichi、Oshima Yoshiteru、Imaizumi Tadaatsu、Seya Kazuhiko
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 154 Issue: 3 Pages: 157-165

    • DOI

      10.1016/j.jphs.2024.01.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21KK0099, KAKENHI-PROJECT-23K08064
  • [Journal Article] Expression of interferon-stimulated gene 20 (ISG20), an antiviral effector protein, in glomerular endothelial cells: possible involvement of ISG20 in lupus nephritis2023

    • Author(s)
      Karasawa Takao、Sato Riko、Imaizumi Tadaatsu、Fujita Masashi、Aizawa Tomomi、Tsugawa Koji、Mattinzoli Deborah、Kawaguchi Shogo、Seya Kazuhiko、Terui Kiminori、Joh Kensuke、Tanaka Hiroshi
    • Journal Title

      Renal Failure

      Volume: 45 Issue: 1 Pages: 2224890-2224890

    • DOI

      10.1080/0886022x.2023.2224890

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07862, KAKENHI-PROJECT-23K08064
  • [Journal Article] Wnt5a pathway was not involved in the progression of valve calcification in calcific aortic valve stenosis2023

    • Author(s)
      Zaiqiang Yu、Kazuyuki Daitoku、Ikuo Fukuda、Tadaatsu Imaizumi、Masahito Minakawa、Ken-Ichi Furukawa、Kazuhiko Seya
    • Journal Title

      Hirosaki Medical Journal

      Volume: 73 Pages: 20-29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K08064
  • [Journal Article] Elucidation of the inhibitory effect of (+)-hopeaphenol on polyinosinic-polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells2022

    • Author(s)
      Liu Xu, Zaiqiang Yu, Yoshinori Uekusa, Shogo Kawaguchi, Haruhisa Kikuchi, Kazuyuki Daitoku, Masahito Minagawa, Shigeru Motomura, Ken-Ichi Furukawa, Yoshiteru Oshima, Kazuhiko Seya, and Tadaatsu Imaizumi
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 149

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09089
  • [Journal Article] Glomerular endothelial expression of type I IFN-stimulated gene, DExD/H-Box Helicase 60 via Toll-like receptor 3 signaling: Possible involvement in the pathogenesis of lupus nephritis.2022

    • Author(s)
      Karasawa T, Sato R, Imaizumi T, Fujita M, Aizawa T, Tsugawa K, Kawaguchi S, Seya K, Terui K, Tanaka H.
    • Journal Title

      Renal Failure

      Volume: 44 Issue: 1 Pages: 137-145

    • DOI

      10.1080/0886022x.2022.2027249

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07862
  • [Journal Article] Elucidation of the inhibitory effect of hopeaphenol on polynosinic- polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells2022

    • Author(s)
      Xu L, Yu Z, Uesaka Y, Kawaguchi S, Kikuchi H, Daitoku K, MInakawa M, MOtomura S, Furukawa KI, Oshima Y, Seya K, Imaizumi T
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 149 Issue: 3 Pages: 147-157

    • DOI

      10.1016/j.jphs.2022.04.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09117
  • [Journal Article] Effects of sera from lupus patients on the glomerular endothelial fibrinolysis system.2022

    • Author(s)
      Sato R, Aizawa T, Imaizumi T, Tsugawa K, Kawaguchi S, Seya K, Terui K, Tanaka H
    • Journal Title

      Pediatrics International

      Volume: 64 Issue: 1

    • DOI

      10.1111/ped.15099

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07862
  • [Journal Article] Sphingomyelin Phosphodiesterase Acid-Like 3b is Essential for Toll-Like Receptor 3 Signaling in Human Podocytes.2022

    • Author(s)
      1.Watanabe S, Umetsu H, Hashimoto S, Sato R, Aizawa T, Tsugawa K, Imaizumi T, Tanaka H
    • Journal Title

      The Journal of Membrane Biology

      Volume: 255 Issue: 1 Pages: 117-122

    • DOI

      10.1007/s00232-021-00206-w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08338, KAKENHI-PROJECT-22K07862
  • [Journal Article] Human aortic valve interstitial cells obtained from patients with aortic valve stenosis are vascular endothelial growth factor receptor 2 positive and contribute to ectopic calcification.2021

    • Author(s)
      Liu Xu、Yu Zaiqiang、Daitoku Kazuyuki、Fukuda Ikuo、Motomura Shigeru、Matsumiya Tomoh、Imaizumi Tadaatsu、Furukawa Ken-Ichi、Seya Kazuhiko
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 145 Issue: 2 Pages: 213-221

    • DOI

      10.1016/j.jphs.2020.12.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09089, KAKENHI-PROJECT-18K16381, KAKENHI-PROJECT-20K09117
  • [Journal Article] Daily Brazilian green propolis intake elevates blood artepillin C levels in humans2021

    • Author(s)
      Ding Jiangli、Matsumiya Tomoh、Hayakari Ryo、Shiba Yuko、Kawaguchi Shogo、Seya Kazuhiko、Ueno Kayo、Imaizumi Tadaatsu
    • Journal Title

      Journal of the Science of Food and Agriculture

      Volume: - Issue: 11 Pages: 4855-4861

    • DOI

      10.1002/jsfa.11132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10012, KAKENHI-PROJECT-19K09089
  • [Journal Article] Interleukin-6 via Toll-Like Receptor 3 Signaling Attenuates the Expression of Proinflammatory Chemokines in Human Podocytes2021

    • Author(s)
      Hidenori Umetsu, Shojiro Watanabe, Tadaatsu Imaizumi, Tomomi Aizawa, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Hiroshi Tanaka
    • Journal Title

      Kidney and Blood Pressure Research

      Volume: - Issue: 2 Pages: 207-218

    • DOI

      10.1159/000514589

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08338
  • [Journal Article] Podocyte sphingomyelin phosphodiesterase acid-like 3b decreases among children with idiopathic nephrotic syndrome2021

    • Author(s)
      Shojiro Watanabe, Koji Hirono, Tomomi Aizawa, Koji Tsugawa, Kensuke Joh, Tadaatsu Imaizumi, Hiroshi Tanaka
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 25 Issue: 1 Pages: 44-51

    • DOI

      10.1007/s10157-020-01970-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08338
  • [Journal Article] Tryptanthrin suppresses double-stranded RNA-induced CXCL10 expression via inhibiting the phosphorylation of STAT1 in human umbilical vein endothelial cells2021

    • Author(s)
      Kawaguchi Shogo、Sakuraba Hirotake、Kikuchi Hidezumi、Numao Noriyuki、Asari Taka、Hiraga Hiroto、Ding Jiangli、Matsumiya Tomoh、Seya Kazuhiko、Fukuda Shinsaku、Imaizumi Tadaatsu
    • Journal Title

      Molecular Immunology

      Volume: 129 Pages: 32-38

    • DOI

      10.1016/j.molimm.2020.11.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10012, KAKENHI-PROJECT-19K09089
  • [Journal Article] Interferon-induced transmembrane protein 1 and Myxovirus resistance protein 1 are induced by polyinosinic-polycytidylic acid in cultured hCMEC/D3 human cerebral microvascular endothelial cells2019

    • Author(s)
      Imaizumi Tadaatsu、Satake Urara、Miyashita Ruri、Kawaguchi Shogo、Matsumiya Tomoh、Seya Kazuhiko、Ding Jiangli、Tanaka Hiroshi
    • Journal Title

      Journal of Neuroimmunology

      Volume: 337 Pages: 577047-577047

    • DOI

      10.1016/j.jneuroim.2019.577047

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10012, KAKENHI-PROJECT-19K09089
  • [Journal Article] Warfarin calcifies human aortic valve interstitial cells at high-phosphate conditions via pregnane X receptor2019

    • Author(s)
      Yu Zaiqiang、Seya Kazuhiko、Chiyoya Mari、Daitoku Kazuyuki、Motomura Shigeru、Imaizumi Tadaatsu、Fukuda Ikuo、Furukawa Ken-Ichi
    • Journal Title

      Journal of Bone and Mineral Metabolism

      Volume: in oress Issue: 6 Pages: 944-956

    • DOI

      10.1007/s00774-019-01001-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10449, KAKENHI-PROJECT-19K09089, KAKENHI-PROJECT-18K16381, KAKENHI-PROJECT-16K10619, KAKENHI-PROJECT-17K10916
  • [Journal Article] Cytosolic sensors of viral RNA are involved in the production of interleukin-6 via Toll-like receptor 3 signaling in human glomerular endothelial cells2019

    • Author(s)
      Liu Q, Imaizumi T, Aizawa T, Hirono K, Kawaguchi S, Watanabe S, Tsugawa K, Matsumiya T, Seya K, Yoshida H, Tanaka H
    • Journal Title

      Kidney Blood Pressure Res

      Volume: 44 Issue: 1 Pages: 62-71

    • DOI

      10.1159/000498837

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09681, KAKENHI-PROJECT-17K10012, KAKENHI-PROJECT-16K10055
  • [Journal Article] Endothelial expression of fractalkine (CX3CL1) is induced by Toll-like receptor 3 signaling in cultured human glomerular endothelial cells2019

    • Author(s)
      Hirono Koji、Imaizumi Tadaatsu、Aizawa Tomomi、Watanabe Shojiro、Tsugawa Koji、Shiratori Toshihiro、Kawaguchi Shogo、Seya Kazuhiko、Matsumiya Tomoh、Ito Etsuro、Tanaka Hiroshi
    • Journal Title

      Modern Rheumatology

      Volume: - Issue: 6 Pages: 1-8

    • DOI

      10.1080/14397595.2019.1682768

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10012, KAKENHI-PROJECT-19K09089, KAKENHI-PROJECT-17K09681
  • [Journal Article] Melanoma Differentiation-Associated Gene 5 Positively Modulates TNF-α-Induced CXCL10 Expression in Cultured HuH-7 and HLE Cells.2019

    • Author(s)
      Shogo Kawaguchi、 Hirotake Sakuraba、 Toshihiro Haga、 Tomoh Matsumiya、 Kazuhiko Seya、 Tetsu Endo、 Naoya Sawada、 Chikara Iino、 Hidezumi Kikuchi、 Hiroto Hiraga、 Shinsaku Fukuda、 Tadaatsu Imaizumi
    • Journal Title

      Inflammation

      Volume: 42 Issue: 6 Pages: 2095-2104

    • DOI

      10.1007/s10753-019-01073-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10012, KAKENHI-PROJECT-19K09089, KAKENHI-PROJECT-19K17449
  • [Journal Article] Chloroquine attenuates TLR3-mediated plasminogen activator inhibitor-1 expression in cultured human glomerular endothelial cells.2019

    • Author(s)
      Aizawa T, Imaizumi T, Hirono K, Watanabe S, Tsugawa K, Tanaka H
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 23 Issue: 4 Pages: 448-454

    • DOI

      10.1007/s10157-018-1659-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10055, KAKENHI-PROJECT-17K09681
  • [Journal Article] Menaquinone-4 Accelerates Calcification of Human Aortic Valve Interstitial Cells in High-Phosphate Medium through PXR2019

    • Author(s)
      Yang Wei、Yu Zaiqiang、Chiyoya Mari、Liu Xu、Daitoku Kazuyuki、Motomura Shigeru、Imaizumi Tadaatsu、Fukuda Ikuo、Furukawa Ken-Ichi、Tsuji Motonori、Seya Kazuhiko
    • Journal Title

      Journal of Pharmacology and Experimental Therapeutics

      Volume: 372 Issue: 3 Pages: 277-284

    • DOI

      10.1124/jpet.119.263160

    • NAID

      130007811872

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09089, KAKENHI-PROJECT-16K10619
  • [Journal Article] Toll-like receptor 3 signaling contributes to regional neutrophil recruitment in cultured human glomerular endothelial cells.2018

    • Author(s)
      Liu Q, Imaizumi T, Kawaguchi S, Aizawa T, Matsumiya T, Watanabe S, Tsugawa K, Yoshida H, Tsuruga K, Joh K, Kijima H, Tanaka H
    • Journal Title

      Nephron

      Volume: 139 Issue: 4 Pages: 349-358

    • DOI

      10.1159/000489507

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09681, KAKENHI-PROJECT-17K10012, KAKENHI-PROJECT-17H04057, KAKENHI-PROJECT-16K10055
  • [Journal Article] <b>DEC1 negatively regulates the expression of CXCL10 and CCL5 induced by poly IC in normal human mesangial </b><b>cells </b>2017

    • Author(s)
      Liu Q, Imaizumi T, Murakami K, Tanaka H, Wu Y, Yoshizawa T, Morohashi S, Seino H, Kijima H
    • Journal Title

      Biomed. Res.

      Volume: 38 Issue: 4 Pages: 249-255

    • DOI

      10.2220/biomedres.38.249

    • NAID

      130005966979

    • ISSN
      0388-6107, 1880-313X
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09681, KAKENHI-PROJECT-17K17575, KAKENHI-PROJECT-15K19763
  • [Journal Article] Chloroquine attenuates TLR3/IFN-β signaling in cultured normal human mesangial cells: A possible protective effect against renal damage in lupus nephritis.2017

    • Author(s)
      Imaizumi T, Hayakari R, Matsumiya T, Yoshida H, Tsuruga K, Watanabe S, Kawaguchi S, Tanaka H.
    • Journal Title

      Mod Rheumatol

      Volume: - Issue: 6 Pages: 1004-8

    • DOI

      10.1080/14397595.2017.1289646

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06766, KAKENHI-PROJECT-16K10055, KAKENHI-PROJECT-17K10012
  • [Journal Article] Urinary excretion of SMPDL-3b in children with intractable nephrotic syndrome.2017

    • Author(s)
      Watanabe S, Tsugawa K, Tsuruga K, Imaizumi T, Tanaka H
    • Journal Title

      Pediatrics International

      Volume: 59 Issue: 10 Pages: 1112-1115

    • DOI

      10.1111/ped.13355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10055, KAKENHI-PROJECT-16K19623
  • [Journal Article] Interferon (IFN)-induced protein 35 (IFI35) negatively regulates IFN-β-phosphorylated STAT1-RIG-I-CXCL10/CCL5 axis in U373MG astrocytoma cells treated with polyinosinic-polycytidylic acid.2017

    • Author(s)
      Shirai K, Shimada T, Yoshida H, Hayakari R, Matsumiya T, Tanji K, Murakami M, Tanaka H, Imaizumi T.
    • Journal Title

      Brain Res.

      Volume: 1658 Pages: 60-67

    • DOI

      10.1016/j.brainres.2017.01.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460567, KAKENHI-PROJECT-15K06766
  • [Journal Article] Cylindromatosis (CYLD), a deubiquitinase, attenuates inflammatory signaling pathways by activating Toll-like receptor 3 in human mesangial cells.2017

    • Author(s)
      Imaizumi T, Hayakari R, Watanabe S, Aizawa T, Matsumiya T, Yoshida H, Tsuruga K, Kawaguch S, Tanaka H
    • Journal Title

      Kidney and Blood Pressure Research

      Volume: 42 Issue: 5 Pages: 942-950

    • DOI

      10.1159/000485084

    • NAID

      120006557467

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10055, KAKENHI-PROJECT-17K09681, KAKENHI-PROJECT-17K10012, KAKENHI-PROJECT-15K06766
  • [Journal Article] Treatment of pediatric-onset lupus nephritis: a proposal of optimal therapy.2017

    • Author(s)
      Tanaka H, Joh K, Imaizumi T.
    • Journal Title

      Clin Exp Nephrol

      Volume: - Issue: 5 Pages: 755-763

    • DOI

      10.1007/s10157-017-1381-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460449, KAKENHI-PROJECT-16K10055
  • [Journal Article] Interferon-Dependent Transcript, Is Involved in a Negative Feedback Loop in Innate Immune Reactions in Human Mesangial Cells.2016

    • Author(s)
      Imaizumi T, Shimada T, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Kawaguchi S, Murakami M, Joh K, Tanaka H.
    • Journal Title

      Nephron

      Volume: 132 Issue: 2 Pages: 144-152

    • DOI

      10.1159/000443934

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06766, KAKENHI-PROJECT-25461204, KAKENHI-PROJECT-25461615, KAKENHI-PROJECT-26460449
  • [Journal Article] Interferon (IFN)-Induced Protein 35 (IFI35), a Type I Interferon-Dependent Transcript, Upregulates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.2016

    • Author(s)
      Imaizumi T, Yano C, Numata A, Tsugawa K, Hayakari R, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K,
    • Journal Title

      Kidney Blood Press Res.

      Volume: 41 Pages: 635-42

    • NAID

      120006557469

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460567
  • [Journal Article] Alteration of Antiviral Signalling by Single Nucleotide Polymorphisms (SNPs) of Mitochondrial Antiviral Signalling Protein (MAVS).2016

    • Author(s)
      Xing F, Matsumiya T, Hayakari R, Yoshida H, Kawaguchi S, Takahashi I, Nakaji S, Imaizumi T.
    • Journal Title

      PLoS One

      Volume: 11 Issue: 3 Pages: e0151173-e0151173

    • DOI

      10.1371/journal.pone.0151173

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06766, KAKENHI-PROJECT-26460567, KAKENHI-PROJECT-26860766
  • [Journal Article] Critical Role of IRF-3 in the Direct Regulation of dsRNA-Induced Retinoic Acid-Inducible Gene-I (RIG-I) Expression.2016

    • Author(s)
      Hayakari R, Matsumiya T, Xing F, Yoshida H, Hayakari M, Imaizumi T.
    • Journal Title

      PLoS One.

      Volume: 11 Issue: 9 Pages: e0163520-e0163520

    • DOI

      10.1371/journal.pone.0163520

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460567, KAKENHI-PROJECT-15K06766
  • [Journal Article] Interferon (IFN)-induced protein 35 (IFI35), a type I interferon-dependent transcript, upregulates inflammatory signaling pathways by activating Toll-like receptor 3 in human mesangial cells.2016

    • Author(s)
      Imaizumi T, Yano C, Numata A, Tsugawa K, Hayakari R, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Kawaguchi S, Murakami M, Tanaka H.
    • Journal Title

      Kidney and Blood Pressure Research

      Volume: 41 Issue: 5 Pages: 635-642

    • DOI

      10.1159/000447932

    • NAID

      120006557469

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10055
  • [Journal Article] Non-Canonical Role of IKKα in the Regulation of STAT1 Phosphorylation in Antiviral Signaling.2016

    • Author(s)
      Xing F, Matsumiya T, Shiba Y, Hayakari R, Yoshida H, Imaizumi T.
    • Journal Title

      PLoS One.

      Volume: 11 Issue: 12 Pages: e0168696-e0168696

    • DOI

      10.1371/journal.pone.0168696

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460567, KAKENHI-PROJECT-15K06766
  • [Journal Article] Clarithromycin attenuates the expression of monocyte chemoattractant protein-1 by activating Toll-like receptor 4 in human mesangial cells.2016

    • Author(s)
      Tsugawa K, Imaizumi T, Watanabe S, Tsuruga K, Yoshida H, Tanaka H.
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: - Issue: 4 Pages: 573-578

    • DOI

      10.1007/s10157-016-1333-1

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K10055, KAKENHI-PROJECT-17K09681
  • [Journal Article] Toll-like receptor 3 signaling contributes to the expression of a neutrophil chemoattractant, CXCL1 in human mesangial cells.2015

    • Author(s)
      Imaizumi T, Aizawa T, Segawa C, Shimada M, Tsuruga K, Kawaguchi S, Matsumiya T, Yoshida H, Joh K, Tanaka H:
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 19 Issue: 5 Pages: 761-770

    • DOI

      10.1007/s10157-014-1060-4

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461204, KAKENHI-PROJECT-25461615
  • [Journal Article] Desferrioxamine, an iron chelator, inhibits CXCL10 expression induced by polyinosinic-polycytidylic acidin U373MG human astrocytoma cells.2015

    • Author(s)
      Imaizumi T, Sakashita N, Mushiga Y, Yoshida H, Hayakari R, Xing F, Wang L, Matsumiya T, Tanji K, Chiba Y, Furudate K, Kawaguchi S, Murakami M, Tanaka H.
    • Journal Title

      Neurosci Res.

      Volume: in press Pages: 10-16

    • DOI

      10.1016/j.neures.2015.01.001

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25460293, KAKENHI-PROJECT-26460567, KAKENHI-PROJECT-26860766
  • [Journal Article] Retinoic acid-inducible gene-I-like receptor (RLR)-mediated antiviral innate immune responses in the lower respiratory tract: Roles of TRAF3 and TRAF5.2015

    • Author(s)
      Chiba Y, Matsumiya T, Satoh T, Hayakari R, Furudate K, Xing F, Yoshida H, Tanji K, Mizukami H, Imaizumi T, Ito E.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 467 Issue: 2 Pages: 191-196

    • DOI

      10.1016/j.bbrc.2015.10.010

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06766, KAKENHI-PROJECT-26460567, KAKENHI-PROJECT-26860766
  • [Journal Article] Mizoribine in the treatment of pediatric-onset glomerular disease: Revisit its beneficial effects from the histological standpoint.2015

    • Author(s)
      Tanaka H, Tsuruga K, Imaizumi T.
    • Journal Title

      World J Pediatr

      Volume: 11 Issue: 2 Pages: 108-112

    • DOI

      10.1007/s12519-015-0013-7

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461615
  • [Journal Article] Mesangial viral and psuedoviral immunity: possible involvement in the pathogenesis of pediatric-onset active lupus nephritis.2015

    • Author(s)
      Tanaka H, Imaizumi T.
    • Journal Title

      Journal of Arthritis

      Volume: 4 Issue: 04 Pages: 183-183

    • DOI

      10.4172/2167-7921.1000183

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461615
  • [Journal Article] Expressions of mRNA for innate immunity-associated functional molecules in urinary sediment in immunoglobulin A nephropathy.2015

    • Author(s)
      Tsuruga K, Aizawa T, Watanabe S, Tsugawa K, Yoshida H, Imaizumi T, Ito E, Tanaka H.
    • Journal Title

      Nephrology (Carlton)

      Volume: 20 Issue: 12 Pages: 916-921

    • DOI

      10.1111/nep.12533

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K06766, KAKENHI-PROJECT-25461204, KAKENHI-PROJECT-25461615
  • [Journal Article] Phosphorylation of serine 349 of p62 in Alzheimer’s disease brain2014

    • Author(s)
      Tanji K, Miki Y, Ozaki T, Maruyama A, Yoshida H, Mimura J, Matsumiya T, Mori F, Imaizumi T, Itoh K, Kakita A, Takahashi H, Wakabayashi K
    • Journal Title

      Acta Neuropathol Comm

      Volume: 2 Issue: 1 Pages: 50-50

    • DOI

      10.1186/2051-5960-2-50

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24300131, KAKENHI-PROJECT-25860202, KAKENHI-PROJECT-25861611, KAKENHI-PROJECT-26460567
  • [Journal Article] Periosteum-derived cells respond to mechanical stretch and activate Wnt and BMP signaling pathways2014

    • Author(s)
      Ito R, Matsumiya T, Kon T, Narita N, Kubota K, Sakaki H, Ozaki T, Imaizumi T, Kobayashi W, Kimura H
    • Journal Title

      Biomed Res

      Volume: 35(1) Pages: 69-79

    • Data Source
      KAKENHI-PROJECT-23590560
  • [Journal Article] Tumor Microenvironment and RIG-I Signaling Molecules in Epstein Barr Virus-positive and -negative Classical Hodgkin Lymphoma of the Elderly2014

    • Author(s)
      Satoh T, Wada R, Yajima N, Imaizumi T, Yagihashi S
    • Journal Title

      J Clin Exp Hematol

      Volume: 54

    • NAID

      130004886479

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591378
  • [Journal Article] Role of type I- and type II-interferon in expression of melanoma differentiation-associated gene-5 in HSC-3 oral squamous carcinoma cells.2014

    • Author(s)
      Matsumiya T, Hayakari R, Narita N, Ito R, Kon T, Kubota K, Sakaki H, Yoshida H, Imaizumi T, Kobayashi W, Kimura H.
    • Journal Title

      Biomed Res

      Volume: 35 Pages: 9-16

    • NAID

      130004903864

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590560
  • [Journal Article] Tumor necrosis factor-α synergistically enhances polyinosinic-polycytidylic acid-induced toll-like receptor 3 signaling in cultured normal human mesangial cells: possible involvement in the pathogenesis of lupus nephritis2014

    • Author(s)
      Imaizumi T, Aizawa T, Hayakari R, Xing F, Meng P, Tsuruga K, Matsumiya T, Yoshida H, Wang L, Tatsuta T, Tanaka H
    • Journal Title

      Clin Exp Nephrol

      Volume: (online ahead of print) Issue: 1 Pages: 75-81

    • DOI

      10.1007/s10157-014-0956-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24791038, KAKENHI-PROJECT-25461204, KAKENHI-PROJECT-25461615, KAKENHI-PROJECT-26860766
  • [Journal Article] Role of type I- and type II-interferon in expression of melanoma differentiation-associated gene-5 in HSC-3 oral squamous carcinoma cells2014

    • Author(s)
      Kon T , Matsumiya T, Hayakari R, Narita N, Ito R, Kubota K, Sakaki H, Yoshida H, Imaizumi T, Kobayashi W, Kimura H
    • Journal Title

      Biomed Res

      Volume: 35(1) Pages: 9-16

    • NAID

      130004903864

    • Data Source
      KAKENHI-PROJECT-23590560
  • [Journal Article] Tumor Microenvironment and RIG-I Signaling Molecules in Epstein Barr Virus-Positive and -Negative Classical Hodgkin Lymphoma of the Elderly2014

    • Author(s)
      Satoh T1, Wada R, Yajima N, Imaizumi T, Yagihashi S
    • Journal Title

      Journal of Clinical and Experimental Hematopathology

      Volume: 54 Issue: 1 Pages: 75-84

    • DOI

      10.3960/jslrt.54.75

    • NAID

      130004886479

    • ISSN
      1346-4280, 1880-9952
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591378
  • [Journal Article] Periosteum-derived cells respond to mechanical stretch and activate Wnt and BMP signaling pathways.2014

    • Author(s)
      Ito R, Matsumiya T, Kon T, Narita N, Kubota K, Sakaki H, Ozaki T, Imaizumi T, Kobayashi W, Kimura H.
    • Journal Title

      Biomed Res

      Volume: 35 Pages: 69-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590560
  • [Journal Article] Efficacy of mizoribine-tacrolimus-based induction therapy for pediatric lupus nephritis2014

    • Author(s)
      Tanaka H, Aizawa T, Watanabe S, Oki E, Tsuruga K, Imaizumi T
    • Journal Title

      Lupus

      Volume: (online ahead of print) Issue: 8 Pages: 813-818

    • DOI

      10.1177/0961203314528553

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24791038, KAKENHI-PROJECT-25461615
  • [Journal Article] Toll-like receptor 3 signaling contributes to the expression of a neutrophil chemoattractant, CXCL1 in human mesangial cells.2014

    • Author(s)
      Imaizumi T, Aizawa T, Segawa C, Shimada M, Tsuruga K, Kawaguchi S, Matsumiya T, Yoshida H, Joh K, Tanaka H.
    • Journal Title

      Clin Exp Nephrol.

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460567
  • [Journal Article] Carnosic acid attenuates apoptosis induced by amyloid-β 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells.2014

    • Author(s)
      Meng P, Yoshida H, Tanji K, Matsumiya T, Xing F, Hayakari R, Wang L, Tsuruga K, Tanaka H, Mimura J, Kosaka K, Itoh K, Takahashi I, Kawaguchi S, Imaizumi T.
    • Journal Title

      Neurosci Res

      Volume: - Pages: 1-9

    • DOI

      10.1016/j.neures.2014.12.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460567, KAKENHI-PROJECT-26860766
  • [Journal Article] Mizoribine selectively attenuates monocyte chemoattractant protein-1 production in cultured human glomerular mesangial cell: a possible benefit of its use in the treatment of lupus nephritis.2014

    • Author(s)
      Aizawa T, Imaizumi T, Tsuruga K, Watanabe S, Chiba Y, Matsumiya T, Yoshida H, Tanaka H.
    • Journal Title

      Nephrology (Carlton)

      Volume: 19 Issue: 1 Pages: 47-52

    • DOI

      10.1111/nep.12171

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592081, KAKENHI-PROJECT-25461615
  • [Journal Article] Carnosic acid suppresses the production of amyloid-beta 1-42 and 1-43 by inducing an alpha-secretase TACE/ADAM17 in U373MG human astrocytoma cells.2014

    • Author(s)
      Yoshida H, Meng P, Matsumiya T, Tanji K, Hayakari R, Xing F, Wang L, Tsuruga K, Tanaka H, Mimura J, Kosaka K, Itoh K, Takahashi I, Imaizumi T
    • Journal Title

      Neurosci Res

      Volume: 79 Pages: 89-94

    • DOI

      10.1016/j.neures.2013.11.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500425, KAKENHI-PROJECT-23590560, KAKENHI-PROJECT-23592081
  • [Journal Article] TLR4 signaling induces retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5 in mesangial cells.2013

    • Author(s)
      Imaizumi T, Aizawa-Yashiro T, Watanabe S, Matsumiya T, Yoshida H, Tatsuta T, Xing F, Meng P, Hayakari R, Tsuruga K, Tanaka H.
    • Journal Title

      J Nephrol

      Volume: 26 Issue: 5 Pages: 886-893

    • DOI

      10.5301/jn.5000254

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592081, KAKENHI-PROJECT-25461204
  • [Journal Article] Novel role for molecular transporter importin 9 in posttranscriptional regulation of IFN-ε expression.2013

    • Author(s)
      Matsumiya T, Xing F, Ebina M, Hayakari R, Imaizumi T, Yoshida H, Kikuchi H, Topham MK, Satoh K, Stafforini DM.
    • Journal Title

      J Immunol

      Volume: 191 Issue: 4 Pages: 1907-15

    • DOI

      10.4049/jimmunol.1201925

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590560, KAKENHI-PROJECT-23592081, KAKENHI-PROJECT-24510081
  • [Journal Article] Glomerular expression of fractalkine is induced by polyinosinic-polycytidylic acid in human mesangial cells : possible involvement of fractalkine after viral infection2013

    • Author(s)
      Aizawa-Yashiro T, Imaizumi T, Tsuruga K, Watanabe S, Matsumiya T, Hayakari R, Yoshida H, Satoh K, Ito E, Tanaka H
    • Journal Title

      Pediatr Res

      Volume: 73 Pages: 180-186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Journal Article] Glomerular expression of fractalkine is induced by polyinosinic-polycytidylic acid in human mesangial cells: possible involvement of fractalkine after viral infection2013

    • Author(s)
      Aizawa-Yashiro T, Imaizumi T, Tsuruga K, Watanabe S, Matsumiya T, Hayakari R, Yoshida H, Satoh K, Ito E, Tanaka H.
    • Journal Title

      Pediatr Res

      Volume: 73 Issue: 2 Pages: 180-186

    • DOI

      10.1038/pr.2012.165

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175, KAKENHI-PROJECT-23592081
  • [Journal Article] Tanaka H. Interaction between interferon-stimulated gene 56 and melanoma differentiation-associated gene 5 in toll-like receptor 3 signaling in normal human mesangial cells2013

    • Author(s)
      Imaizumi T, Aizawa-Yashiro T, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Tatsuta T, Xing F, Hayakari R, Meng P
    • Journal Title

      Am J Nephrol

      Volume: 37 Pages: 118-125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Journal Article] Interaction between interferon-stimulated gene 56 and melanoma differentiation-associated gene 5 in toll-like receptor 3 signaling in normal human mesangial cells2013

    • Author(s)
      Imaizumi T, Aizawa-Yashiro T, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Tatsuta T, Xing F, Hayakari R, Meng P, Tanaka H.
    • Journal Title

      Am J Nephrol

      Volume: 37 Issue: 2 Pages: 118-125

    • DOI

      10.1159/000346415

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175, KAKENHI-PROJECT-23592081, KAKENHI-PROJECT-25461204
  • [Journal Article] Urinary fractalkine and monocyte chemoattractant protein-1 as possible predictors of disease activity of childhood glomerulonephritis.2013

    • Author(s)
      Aizawa T, Imaizumi T, Tsuruga K, Watanabe S, Yoshida H, Kumagai N, Ito E, Tanaka H.
    • Journal Title

      Tohoku J Exp Med

      Volume: 231 Pages: 265-270

    • NAID

      130004822389

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461204
  • [Journal Article] Inflammatory chemokine expression via toll-like receptor 3 signaling in normal human mesangial cells.2013

    • Author(s)
      Tanaka H, Imaizumi T
    • Journal Title

      Clin Dev Immunol

      Volume: 2013 Pages: 984708-984708

    • DOI

      10.1155/2013/984708

    • NAID

      120006557468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461615
  • [Journal Article] Urinary Fractalkine and Monocyte Chemoattractant Protein-1 as Possible Predictors of Disease Activity of Childhood Glomerulonephritis2013

    • Author(s)
      Aizawa T, Imaizumi T, Tsuruga K, Watanabe S, Kumagai N, Yuki Chiba, Yoshida H, Ito E, Tanaka H
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 231 Issue: 4 Pages: 265-270

    • DOI

      10.1620/tjem.231.265

    • NAID

      130004822389

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461615
  • [Journal Article] Glomerular expression of myxovirus resistance protein 1 (Mx1) in human mesangial cells: possible activation of innate immunity in the pathogenesis of lupus nephritis.2013

    • Author(s)
      Watanabe S, Imaizumi T, Tsuruga K, Aizawa T, Ito T, Matsumiya T, Yoshida H, Joh K, Ito E, Tanaka H:
    • Journal Title

      Nephrology

      Volume: 18 Pages: 833-837

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461204
  • [Journal Article] Glomerular expression of myxovirus resistance protein 1 in human mesangial cells: possible activation of innate immunity in the pathogenesis of lupus nephritis.2013

    • Author(s)
      Watanabe S, Imaizumi T, Tsuruga K, Aizawa T, Ito T, Matsumiya T, Yoshida H, Joh K, Ito E, Tanaka H.
    • Journal Title

      Nephrology (Carlton)

      Volume: 18 Issue: 12 Pages: 833-837

    • DOI

      10.1111/nep.12155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592081, KAKENHI-PROJECT-25461615
  • [Journal Article] How are STAT1 and cholesterol metabolism associated in antiviral responses?2013

    • Author(s)
      Matsumiya T, Imaizumi T
    • Journal Title

      J AK-STAT

      Volume: 2(3) Issue: 3 Pages: e24189-e24189

    • DOI

      10.4161/jkst.24189

    • Data Source
      KAKENHI-PROJECT-23590560
  • [Journal Article] Fukuda S : Expression of melanoma differentiation associated gene 5 (MDA5) is increased in human gastric mucosa infected with Helicobacter pyroli2012

    • Author(s)
      Tatsuta T, Imaizumi T, Shimoyama T,Sawaya M, Tanji K, Matsumiya T, Yoshida H, Satoh K
    • Journal Title

      J Clin Pathol

      Volume: 65 Issue: 9 Pages: 839-843

    • DOI

      10.1136/jclinpath-2011-200590

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259, KAKENHI-PROJECT-23592081
  • [Journal Article] Sawamura D. : Characterization of retinoic acid-inducible gene-I (RIG-I) expression corresponding to viral infection and UVB in human keratinocytes2012

    • Author(s)
      Kimura K, Matsuzaki Y, Nishikawa Y, Kitamura H, Akasaka E, Rokunohe D, Nakano H, Imaizumi T, Satoh K
    • Journal Title

      J Dermatol Sci 2012

      Volume: 66(1) Issue: 1 Pages: 66-70

    • DOI

      10.1016/j.jdermsci.2012.02.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259, KAKENHI-PROJECT-23591611
  • [Journal Article] Melanoma Differentiation-Associated Gene 5 Regulates the Expression of a Chemokine CXCL10 in Human Mesangial Cells: Implications for Chronic Inflammatory Renal Diseases2012

    • Author(s)
      Imaizumi T, Aizawa-Yashiro T, Tsuruga K, Tanaka H, Matsumiya T, Yoshida H, Tatsuta T, Xing F, Hayakari R, Satoh K
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 228 Issue: 1 Pages: 17-26

    • DOI

      10.1620/tjem.228.17

    • NAID

      130004459999

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259, KAKENHI-PROJECT-22591175
  • [Journal Article] Melanoma differentiation-associated gene 5 regulates the expression of a chemokine CXCL10 in human mesangial cells: implications for chronic inflammatory renal diseases.2012

    • Author(s)
      Imaizumi T et al.
    • Journal Title

      Tohoku J Exp Med

      Volume: 228 Pages: 17-26

    • NAID

      10031025369

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] Melanoma differentiation-associated gene 5 regulates the expression of a chemokine CXCL10 in human mesangial cells : implications for chronic inflammatory renal diseases2012

    • Author(s)
      Imaizumi T, Aizawa-Yashiro T, Tsuruga K, Tanaka H, Matsumiya T, Yoshida H, Tatsuta T, Xing F, Hayakari R, Satoh K
    • Journal Title

      Tohoku J Exp Med

      Volume: 228 Pages: 17-26

    • NAID

      10031025369

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Journal Article] Double-stranded RNA induces biphasic STAT1 phosphorylation by both type I IFN-dependent and type I IFN-independent pathways2012

    • Author(s)
      Dempoya J, Matsumiya T, Imaizumi T, Hayakari R, Xing F, Yoshida H, Okumura K, Satoh K
    • Journal Title

      J Virol

      Volume: 86(23) Issue: 23 Pages: 12760-12769

    • DOI

      10.1128/jvi.01881-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259, KAKENHI-PROJECT-23590560, KAKENHI-PROJECT-23591077, KAKENHI-PROJECT-23592081
  • [Journal Article] Foreign RNA induces the degradation of mitochondrial antiviral signaling protein (MAVS)the role of intracellular antiviral factors.2012

    • Author(s)
      Xing F, Matsumiya T, Onomoto K, Hayakari R, Imaizumi T, Yoshida H, Yoneyama M, Fijita T, Satoh K
    • Journal Title

      PLoS One

      Volume: 7(9) Issue: 9 Pages: e45136-e45136

    • DOI

      10.1371/journal.pone.0045136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259, KAKENHI-PROJECT-23390108, KAKENHI-PROJECT-23590560, KAKENHI-PROJECT-23592081, KAKENHI-PROJECT-23890029, KAKENHI-PLANNED-20112009
  • [Journal Article] Polyinosinic-polycytidylic acid induces the expression of interferon-stimulated gene 20 in mesangial cells2011

    • Author(s)
      Imaizumi T, Tanaka H, Mechti N, Matsumiya T, Yoshida H, Sato F, Aizawa-Yashiro T, Tsuruga K, Hayakari R, Satoh K
    • Journal Title

      Nephron Exp Nephrol

      Volume: 119(2) Issue: 2 Pages: e40-e48

    • DOI

      10.1159/000328923

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259, KAKENHI-PROJECT-22591175, KAKENHI-PROJECT-23590560, KAKENHI-PROJECT-23592081
  • [Journal Article] Basic-helix-loop-helix transcription factor DEC2 constitutes negative feedback loop in IFN-γ-mediated inflammatory responses in human mesangial cells2011

    • Author(s)
      Imaizumi T, Tanaka H, et al.
    • Journal Title

      Immunology Letter

      Volume: 136 Pages: 36-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Journal Article] Antiviral signaling through retinoic acid-inducible gene-I-like receptors.2011

    • Author(s)
      Matsumiya T, Imaizumi T, Yoshida H, Satoh K
    • Journal Title

      Arch Immunol Ther Exp(Warsz) 59(1)

      Pages: 41-8

    • Data Source
      KAKENHI-PROJECT-20591934
  • [Journal Article] Edaravone and carnosic acid synergistically enhance the expression of nerve growth factor in human astrocytes under hypoxia/reoxygenation2011

    • Author(s)
      Yoshida H, Mimura J, Imaizumi T, Matsumiya T, Ishikawa A, Metoki N, Tanji K, Ota K, Hayakari R, Kosaka K, Itoh K, Satoh K
    • Journal Title

      Neurosci Res

      Volume: 69 Issue: 4 Pages: 291-298

    • DOI

      10.1016/j.neures.2010.12.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23590560, KAKENHI-PROJECT-23592081
  • [Journal Article] Basic-helix-loop-helix transcription factor DEC2 constitutes negative feedback loop in IFN-g-mediated inflammatory responses in human mesangial cells.2011

    • Author(s)
      Imaizumi T, Yoshida T, Sato F, Tanaka H, Yashiro-Aizawa K, Hayakari R, Kijima H, Matsumiya T, Tsuruga H, Satoh K
    • Journal Title

      Immunol Lett

      Volume: 136 Issue: 1 Pages: 37-43

    • DOI

      10.1016/j.imlet.2010.11.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259, KAKENHI-PROJECT-23592081, KAKENHI-PROJECT-23792139
  • [Journal Article] Basic-helix-loop-helix transcription factor DEC2 constitutes negative feedback loop in IFN-β-mediated inflammatory responses in human mesangial cells2011

    • Author(s)
      Imaizumi T, Sato F, Tanaka H, Matsumiya T, Yoshida H, Yashiro-Aizawa T, Tsuruga K, Hayakari R, Kijima H, Satoh K
    • Journal Title

      Immunol Lett

      Volume: 136(1) Pages: 37-43

    • Data Source
      KAKENHI-PROJECT-23590560
  • [Journal Article] Imbalance towards Th_1 pathway predominance in purpura nephritis with proteinuria2011

    • Author(s)
      Tsuruga K, Watanabe S, Oki E, Aizawa-Yashiro T, Yoshida H, Imaizumi T, Ito E, Tanaka H
    • Journal Title

      Pediatr Nephrol

      Volume: 26 Pages: 2253-2258

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Journal Article] Imbalance towards Th1 pathway predominance in purpura neohritis with proteinuria.2011

    • Author(s)
      Tsuruga K, Watanabe S, Oki E, Aizawa-Yashiro T, Yoshida H, Imaizumi T, Ito E, Tanaka H
    • Journal Title

      Pediat Nephrol

      Volume: 26 Issue: 12 Pages: 2253-2258

    • DOI

      10.1007/s00467-011-1996-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259, KAKENHI-PROJECT-22591175, KAKENHI-PROJECT-23592081
  • [Journal Article] Polyinosinic-polycytidylic acid induces the expression of interferon-stimulated gene 20 in mesangial cells2011

    • Author(s)
      Imaizumi T, Tanaka H, Mechti N, Matsumiya T, Yoshida H, Aizawa-Yashiro T, Tsuruga K, Hayakari R, Satoh K
    • Journal Title

      Nephron Exp Nephrol

      Volume: 119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Journal Article] Basic-helix-loop-helix transcription factor DEC2 constitutes negative feedback loop in IFN-β-mediated inflammatory responses in human mesangial cells.2011

    • Author(s)
      Imaizumi T, Sato F, Tanaka H, Matsumiya T, Yoshida H, Yashiro-Aizawa T, Tsuruga K, Hayakari R, Kijima H, Satoh K.
    • Journal Title

      Immunol Lett.

      Volume: 136 (1) Pages: 37-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590560
  • [Journal Article] Type-III interferon, not type-I, is the predominant interferon induced by respiratory viruses in nasal epithelial cells.2011

    • Author(s)
      Okabayashi T, Kojima T, Masaki T, Yokota SI, Imaizumi T, Tsutsumi H, Himi T, Fujii N, Sawada N
    • Journal Title

      Virus Res

      Volume: 160(1-2) Issue: 1-2 Pages: 360-366

    • DOI

      10.1016/j.virusres.2011.07.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259, KAKENHI-PROJECT-23390398
  • [Journal Article] Basic-helix-loop-helix transcription factor DEC2 constitutes negative feedback loop in IFN-γ-mediated inflammatory responses in human mesangial cells2011

    • Author(s)
      Imaizumi T, Sato F, Tanaka H, Matsumiya T, Yoshida H, Aizawa-Yashiro T, Tsuruga K, Hayakari R, Kijima H, Sato K
    • Journal Title

      Immunol Lett

      Volume: 136 Pages: 37-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Journal Article] vone and carnosic acid synergistically enhance the expression of nerve growth factor in human astrocytes under hypoxia/reoxygenation.2011

    • Author(s)
      Yoshida H, Mimura J, Imaizumi T, Matsumiya T, Ishikawa A, Metoki N, Tanji K, Ota K, Hayakari R, Kosaka K, Itoh K, Satoh K.
    • Journal Title

      Neurosci Res

      Volume: 69 (4) Pages: 291-298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590560
  • [Journal Article] Polyinosinic-polycytidylic acid induces the expression of interferon-stimulated gene 20 in mesangial cells.2011

    • Author(s)
      Imaizumi T, Tanaka H, Mechti N, Matsumiya T, Yoshida H, Sato F, Aizawa-Yashiro T, Tsuruga K, Hayakari R, Satoh K.
    • Journal Title

      Nephron Exp Nephrol.

      Volume: 119 (2)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590560
  • [Journal Article] Retinoic acid-inducible gene-I is induced by double-stranded RNA and regulates the expression of CC chemokine ligand (CCL) 5 in human mesangial cells2010

    • Author(s)
      Imaizumi T, Tanaka H, Matsumiya T, Yoshida H, Tanji K, Tsuruga K, Oki E, Aizawa-Yashiro T, Ito E, Satoh K
    • Journal Title

      Nephrol Dial Transplant

      Volume: 25 Pages: 3534-3539

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Journal Article] Edaravone improves the expression of nerve growth factor in human astrocytes subjected to hypoxia/reoxygenation2010

    • Author(s)
      Yoshida H, Metoki N, Ishikawa A, Imaizumi T, Matsumiya T, Tanji K, Ota K, Ohyama C, Satoh K
    • Journal Title

      Neurosci Res

      Volume: 66(3) Issue: 3 Pages: 284-289

    • DOI

      10.1016/j.neures.2009.11.011

    • NAID

      10027501032

    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] Retinoic acid-inducible gene-I is induced by double-stranded RNA and regulates the expression of CCL5 in human mesangial cells2010

    • Author(s)
      Imaizumi T, Tanaka H, Matsumiya T, Yoshida H, Tanji K, Tsuruga K, Oki E, Yashiro T, Ito E, Satoh K
    • Journal Title

      Nephrol Dial Transplant

      Volume: 25 Issue: 11 Pages: 3534-3539

    • DOI

      10.1093/ndt/gfq270

    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] Characterization of synergistic induction of CX3CL1/Fractalkine by TNF-α and IFN-γ in vascular endothelial cells2010

    • Author(s)
      Matsumiya T, Ota K, Imaizumi T, Yoshida H, Kimura H, Satoh K
    • Journal Title

      an essential role for TNF-a in post-transcriptional regulation of CX3CL1. J Immunol

      Volume: 184 Issue: 8 Pages: 4205-4214

    • DOI

      10.4049/jimmunol.0903212

    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] Retinoic acid-inducible gene-I (RIG-I) is induced by IFN-γ in human mesangial cells in culture : possible involvement of RIG-I in the inflammation in lupus nephritis2010

    • Author(s)
      Imaizumi T, Tanaka H, Tajima A, Tsuruga K, Oki E, Sashinami H, Matsumiya T, Yoshida H, Inoue I, Ito E
    • Journal Title

      Lupus

      Volume: 19 Pages: 830-836

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Journal Article] Retinoic acid-inducible gene-I is induced by double-stranded RNA and regulates the expression of CCL5 in human mesangial cells.2010

    • Author(s)
      Imaizumi T, Tanaka H, Matsumiya T, Yoshida H, Tanji K, Tsuruga K, Oki E, Yashiro T, Ito E, Satoh K
    • Journal Title

      Nephrol Dial Transplant

      Volume: 25 Pages: 3534-3539

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] Interferon-α2b induces p21cip1/waf1 degradation and cell proliferation in HeLa cells.2010

    • Author(s)
      Ota K, Matsumiya T, Sakuraba H, Imaizumi T, Yoshida H, Kawaguchi S, Fukuda S, Satoh K
    • Journal Title

      Cell Cycle 9(1)

      Pages: 131-9

    • Data Source
      KAKENHI-PROJECT-20591934
  • [Journal Article] Retinoic acid-inducible gene-I (RIG-I) is induced by IFN-γI in human mesangial cells in culture : possible involvement of RIG-I in the inflammation in lupus nephritis.2010

    • Author(s)
      Imaizumi T, Tanaka H, Tajima A, Tsuruga K, Oki E, Sashinami H, Matsumiya T, Yoshida H, Inoue I, Ito E.
    • Journal Title

      Lupus

      Volume: 19 Pages: 830-836

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] Retinoic acid-inducible gene-I (RIG-I) is induced by IFN-γ in human mesangial cells in culture2010

    • Author(s)
      Imaizumi T, Tanaka H, Tajama A, Tsuruga K, Oki E, Sashinami H, Matsumiya T, Yoshida H, Inoue I, Ito E
    • Journal Title

      possible involvement of RIG-I in the inflammation in lupus nephritis. Lupus

      Volume: 19(6) Issue: 7 Pages: 830-836

    • DOI

      10.1177/0961203309360540

    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] IFN-γ and TNF-α synergistically induce microRNA-155 which regulates TAB2/IP-10 expression in human mesangial cells.2010

    • Author(s)
      Imaizumi T, Matsumiya T, 他
    • Journal Title

      Am J Nephrol 32(5)

      Pages: 462-8

    • Data Source
      KAKENHI-PROJECT-20591934
  • [Journal Article] Retinoic acid-inducible gene-I(RIG-I) is induced by IFN-gamma in human mesangial cells in culture : possible involvement of RIG-I in the inflammation in lupus nephritis.2010

    • Author(s)
      Imaizumi T, Tanaka H, Tajima A, Tsuruga K, Oki E, Sashinami H, Matsumiya T, Yoshida H, Inoue I, Ito E
    • Journal Title

      Lupus 19(7)

      Pages: 830-6

    • Data Source
      KAKENHI-PROJECT-20591934
  • [Journal Article] IFN-γ and TNF-α synergistically induce microRNA-155 which regulates TAB2/IP-10 expression in human mesangial cells2010

    • Author(s)
      Imaizumi T, Tanaka H, Tajima A, Yokono Y, Matsumiya T, Yoshida H, Tsuruga K, Aizawa-Yashiro T, Hayakari R, Inoue I, Ito E, Satoh K
    • Journal Title

      Am J Nephrol

      Volume: 32 Issue: 5 Pages: 462-468

    • DOI

      10.1159/000321365

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259, KAKENHI-PROJECT-22241049
  • [Journal Article] Characterization of synergistic induction of CX3CL1/fractalkine by TNF-α and IFN-γ in vascular endothelial cells: an essential role for TNF-α in post-transcriptional regulation of CX3CL1.2010

    • Author(s)
      Matsumiya T, Ota K, Imaizumi T, Yoshida H, Kimura H, Satoh K
    • Journal Title

      J Immunol 184(8)

      Pages: 4205-14

    • Data Source
      KAKENHI-PROJECT-20591934
  • [Journal Article] IFN-γ and TNF-α synergistically induce microRNA-155 which regulates TAB2/IP-10 expression in human mesangial cells2010

    • Author(s)
      Imaizumi T, Tanaka H, Tajima A, Yokono Y, Matsumiya T, Yoshida H, Tsuruga K, Aizawa-Yashiro T, Inoue I, Ito E, Satoh K
    • Journal Title

      Am J Nephrol

      Volume: 32 Pages: 462-468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Journal Article] IFN-γ and TNF-α synergistically induce microRNA-155 which regulates TAB2/IP-10 expression in human mesangial cells2010

    • Author(s)
      Imaizumi T, Tanaka H, et al
    • Journal Title

      American Journal of Nephrology

      Volume: 32 Pages: 462-468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Journal Article] IFN-γ and TNF-a synergistically induce microRNA-155 which regulates TAB2/IP-10 expression in human mesangial cells.2010

    • Author(s)
      Imaizumi T, Tanaka H, Tajima A, Yokono Y, Matsumiya T, Yoshida H, Tsuruga K, Aizawa-Yashiro T, Hayakari R, Inoue I, Ito E, Satoh K.
    • Journal Title

      Am J Nephrol

      Volume: 32 Pages: 462-468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] Retinoic acid-inducible gene-I is induced by double-stranded RNA and regulates the expression of CC chemokine ligand(CCL) 5 in human mesangial cells2010

    • Author(s)
      Imaizumi T, Tanaka H, et al.
    • Journal Title

      Nephrology Dialysis Transplantation

      Volume: 25 Pages: 3534-3539

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Journal Article] Edaravone improves the expression of nerve growth factor in human astrocytes subjected to hypoxia/reoxygenation.2010

    • Author(s)
      Yoshida H, Metoki N, Ishikawa A, Imaizumi T, Matsumiya T, Tanji K, Ota K, Ohyama C, Satoh K
    • Journal Title

      Neurosci Res 66(3)

      Pages: 284-9

    • NAID

      10027501032

    • Data Source
      KAKENHI-PROJECT-20591934
  • [Journal Article] Potential Th1/Th2 predominance in children with newly diagnosed IgA nephropathy2010

    • Author(s)
      Tsuruga K, Oki E, Aizawa-Yashiro T, Yoshida H, Imaizumi T, Tanaka H
    • Journal Title

      Acta Paediatr

      Volume: 99 Pages: 1584-1586

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Journal Article] Potential Th1/Th2 predominance in children with newly diagnosed IgA nephropathy2010

    • Author(s)
      Tsuruga K, Oki E, Aizawa-Yashiro T, Yoshida H, Imaizumi T, Tanaka H
    • Journal Title

      Acta Paediatr

      Volume: 99 Issue: 10 Pages: 1584-1586

    • DOI

      10.1111/j.1651-2227.2010.01881.x

    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] The levels of retinoic acid-inducible gene-I are regulated by heat shock protein 90-α2009

    • Author(s)
      Matsumiya T, Imaizumi T, Yoshida H,Satoh K, Topham MK, Stafforini DM
    • Journal Title

      J Immunol

      Volume: 182(5) Issue: 5 Pages: 2717-2725

    • DOI

      10.4049/jimmunol.0802933

    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] The levels of retinoic acid-induciblegene-I are regulated by heat shock protein90-α2009

    • Author(s)
      Matsumiya T, Imaizumi T, Yoshida H,Satoh K, Topham MK, Stafforini DM
    • Journal Title

      J Immunol 182

      Pages: 2717-2725

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] The viral RNA recognition sensor RIG-I is degraded during encephalomyocarditis virus (EMCV)2009

    • Author(s)
      Papon L, Oteiza A, Imaizumi T, Kato H, Brocchi E, Lawson TG, Akira S, Mechti N
    • Journal Title

      infection. Virology

      Volume: 393(2) Issue: 2 Pages: 311-318

    • DOI

      10.1016/j.virol.2009.08.009

    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] Retinoic acid-inducible gene-I is constitutively expressed and involved in IFN-γ-stimulated CXCL9-11 production in intestinal epithelial cells.2009

    • Author(s)
      Kawaguchi S, Ishiguro Y, Imaizumi T, Mori F, Matsumiya T, Yoshida H, Ota K, Sakuraba H, Yamagata K, Sato Y, Tanji K, Haga T, Wakabayashi K, Fukuda S, Satoh K
    • Journal Title

      Immunol Lett 123

      Pages: 9-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] Tumor-necrosis factor-α induces retinoic acid-inducible gene-I in rheumatoid fibroblast-like synoviocytes.2009

    • Author(s)
      Imaizumi T, Matsumiya T, Yoshida H, Naraoka T, Uesato R, Ishibashi Y, Ota K, Toh S, Fukuda S, Satoh K
    • Journal Title

      Immunol Lett 122

      Pages: 83-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] Tumor-necrosis factor-alpha induces retinoic acid-inducible gene-I in rheumatoid fibroblast-like synoviocytes.2009

    • Author(s)
      Imaizumi T, Matsumiya T, Yoshida H, Naraoka T, Uesato R, Ishibashi Y, Ota K, Toh S, Fukuda S, Satoh K
    • Journal Title

      Immunol Lett. 122(1)

      Pages: 89-93

    • Data Source
      KAKENHI-PROJECT-20591934
  • [Journal Article] The viral RNA recognition sensor RIG-I is degraded during encephalomyocarditis virus(EMCV)infection.2009

    • Author(s)
      Papon L, Oteiza A, Imaizumi T, Kato H, Brocchi E, Lawson TG, Akira S, Mechti N
    • Journal Title

      Virology 393

      Pages: 311-318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] Retinoic acid-inducible gene-I is constitutively expressed and involved in IFN-γ-stimulated CXCL9-11 production in intestinal epithelial cells2009

    • Author(s)
      Kawaguchi S, Ishiguro Y, Imaizumi T, Mori F, Matsumiya T, Yoshida H, Ota K, Sakuraba H, Yamagata K, Sato Y, Tanji K, Haga T, Wakabayashi K, Fukuda S, Satoh K
    • Journal Title

      Immunol Lett

      Volume: 123(1) Issue: 1 Pages: 9-13

    • DOI

      10.1016/j.imlet.2009.01.008

    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] Tumor-necrosis fiefor-α induces retinoic acid-inducible gene-I in rheumatoid fibroblast-like synoviocytes.2009

    • Author(s)
      Imaizumi T, Matsutmiya T, Yoshida H, Naraoka T, Uesato R, Ishibashi Y,Ota, K, Toh S, Fukuda S, Satoh K.
    • Journal Title

      Immunol Lett 122

      Pages: 83-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Tumor-necrosis factor-α induces retinoic acid-inducible gene-I in rheumatoid fibroblast-like synoviocytes2009

    • Author(s)
      Imaizumi T, Matsumiya T, Yoshida H, Naraoka T, Uesato R, Ishibashi Y, Ota K, Toh S, Fukuda S, Satoh K
    • Journal Title

      Immunol Lett

      Volume: 122 Issue: 1 Pages: 89-93

    • DOI

      10.1016/j.imlet.2008.12.005

    • Data Source
      KAKENHI-PROJECT-21591259
  • [Journal Article] The levels of retinoic acid-inducible gene I are regulated by heat shock protein 90-alpha.2009

    • Author(s)
      Matsumiya T, Imaizumi T, Yoshida H, Satoh K, Topham MK, Stafforini DM
    • Journal Title

      J Immunol 182(5)

      Pages: 2717-25

    • Data Source
      KAKENHI-PROJECT-20591934
  • [Journal Article] Tumor-necrosisfactor-α induces retinoicacid-inducible gene-I in rheumatoidfibroblast-like synoviocytes2009

    • Author(s)
      Imaizumi T, Matsumiya T, Yoshida H,Naraoka T, Uesato R, Ishibashi Y, Ota K, Toh S, Fukuda S, Satoh K
    • Journal Title

      Immunol Lett 122

      Pages: 89-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Regulationof IkB kinase-related kinases andantiviral responses by tumor suppressor CYLD2008

    • Author(s)
      Zhang M, Wu X, Lee AJ, Jin W, Chang M, Wright A, Imaizumi T, Sun SC
    • Journal Title

      J Biol Chem 283

      Pages: 18621-18626

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Expression of mRNA forfunctional molecules in urinary sedimentin glomerulonephritis2008

    • Author(s)
      Tsugawa K, Suzuki K, Oki E, Imaizumi T, Ito E, Tanaka H
    • Journal Title

      Pediatr Nephrol 23

      Pages: 395-401

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Retinoic acid-inducible gene-I is induced by interferon-gamma and regulates CXCL11 expression in HeLa cells.2008

    • Author(s)
      Yuzawa E, Imaizumi T, Matsumiya T, Yoshida H, Fukuhara R, Kimura H, Fukui A, Tanji K, Mori F, Wakabayashi K, Fujii S, Mizunuma H, Satoh K
    • Journal Title

      Life Sci 82(11-12)

      Pages: 670-5

    • Data Source
      KAKENHI-PROJECT-20591934
  • [Journal Article] Negative feedback regulation ofRIG-I-mediated anti-viral signaling byinterferon-induced ISG15 conjugation2008

    • Author(s)
      Kim MJ, Hwang SY, Imaizumi T, Yoo JY
    • Journal Title

      J Virol 82

      Pages: 1474-83

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Involvement of retinoic acid-inducible gene-I (RIG-I) in inflammation of rheumatoid fibroblast-like synoviocytes.2008

    • Author(s)
      Imaizumi T, Arikawa T, Sato T, Uesato R, Matsumiya T, Yoshida H, Ueno M, Yamasaki S, Nakajima T, Hirashima M, Sakata K, lshibashi Y, Toh S, Ohyama C, Satoh K.
    • Journal Title

      Clin Exp Imunol 153

      Pages: 240-244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Expression of interferon-stimulated gene 20 in vascular endothelial cells.2008

    • Author(s)
      Imaizumi T, Mechti N, Matsumiya T, Sakaki H, Kubota K, Yoshida H, Kimura H, Satoh K
    • Journal Title

      Microbiol Immunol 52(1)

      Pages: 30-35

    • NAID

      10025691025

    • Data Source
      KAKENHI-PROJECT-20591934
  • [Journal Article] Regulation of IkB kinase-related kinases and antiviral responses by tumor suppressor CYLD.2008

    • Author(s)
      Zhang M, Wu X, Lee Aj, Jin W, Chang M, Wright A, Imaizumi T,Sun SC.
    • Journal Title

      J Biol Chem 283

      Pages: 18621-18656

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Retinoicacid-inducible gene-I is induced by interferon-γ and regulates CXCL11expression in HeLa cells2008

    • Author(s)
      Yuzawa E, Imaizumi T, Matsumiya T, Yoshida H, Fukuhara R, Kimura H, Fukui A,Tanji K, Mori F, Wakabayashi K, Fujii S, Mizunuma H, Satoh K
    • Journal Title

      Life Sci 82

      Pages: 670-675

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Involvement of retinoic acid-induciblegene-I (RIG-I) in inflammation ofrheumatoid fibroblast-like synoviocytes2008

    • Author(s)
      Imaizumi T, Arikawa T, Sato T, Uesato R, Matsumiya T, Yoshida H, Ueno M, Yamasaki S, Nakajima T, Hirashima M, Sakata K, Ishibashi Y, Toh S, Ohyama C, Satoh K
    • Journal Title

      Clin Exp Imunol 153

      Pages: 240-244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Retinoic acid-inducible gene-Imediates RANTES/CCL5 expression in U373MGhuman astrocytoma cells stimulated withdouble-stranded RNA2007

    • Author(s)
      Yoshida H, Imaizumi T, Lee SJ, Tanji K,Sakaki H,Matsumiya T, Ishikawa A, Taima K,Yuzawa E, Mori F, Wakabayashi K, Kimura H,Satoh K
    • Journal Title

      Neurosci Res 58

      Pages: 199-206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Regulation of CXCL-8(Interleukin8)Induction by dsRNA Signaling Pathways During Hepatitis C Virus Infection.2007

    • Author(s)
      Wagoner J, Austin M, Green J, Imaizumi T, Casola A, Brasier A, Khabar KS, Wakita T, Gale M Jr, Polyak SJ
    • Journal Title

      J Virol. 81

      Pages: 309-318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Cytokine modulation of retinoic acid-inducible gene-I(RIG-I)expression in human epidermal keratinocytes.2007

    • Author(s)
      Kitamura H, Matsuzaki Y, Kimura K, Nakano H, Imaizumi T, Satoh K, Hanada K
    • Journal Title

      J Dermatol Sci 45

      Pages: 127-134

    • NAID

      10024115326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Expression of retinoic acid-inducible gene-I in lupus nephritis.2007

    • Author(s)
      Suzuki K, Imaizumi T, Tsugawa K, Ito E, Tanaka H.
    • Journal Title

      Nephrol Dial Transplant 22

      Pages: 2407-2409

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Regulation of CXCL-8 (Interleukin 8) induction by ds RNA signaling pathways during Hepatitis Cvirus infection2007

    • Author(s)
      Wagoner J, Austin M, Green J, ImaizumiT, Casola A, Brasier A, Khabar KS, WakitaT, Gale M Jr, Polyak SJ
    • Journal Title

      J Virol 81

      Pages: 309-318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Expression of retinoic acid-inducible gene-I(RIG-I)in macrophages:possible involvement of RIG-I in atherosclerosis.2007

    • Author(s)
      Imaizumi T, Yagihashi N, Kubota K, Yoshida H, Sakaki H, Yagihashi S, Kimura H, Satoh K
    • Journal Title

      J Atheroscler Thromb 14

      Pages: 51-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Interferon-γ upregulates retinoicacid-inducible gene-I in humanpericardial mesothelial cells2007

    • Author(s)
      Hatakeyama M, Imaizumi T, Terasaki F,Mori F, Tanji K, Sato F, Kijima H, Suma H,Wakabayashi K, Yoshida H, Fukuda I, SatohK
    • Journal Title

      Acta Cardiol 62(6)

      Pages: 551-555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Expression of retinoicacid-inducible gene-I in lupus nephritis2007

    • Author(s)
      Suzuki K, Imaizumi T, Tsugawa K, Ito E, Tanaka H
    • Journal Title

      Nephrol Dial Transplant 22

      Pages: 2407-2409

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Cytokine modulation of retinoicacid-inducible gene-I (RIG-I) expressionin human epidermal keratinocytes2007

    • Author(s)
      Kitamura H, Matsuzaki Y, Kimura K,Nakano H, Imaizumi T, Satoh K, Hanada K
    • Journal Title

      J Dermatol Sci 45

      Pages: 127-134

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Retinoic acid-inducible gene-I mediates RANTES/CCL5 expression in U373MG human astrocytoma cells stimulated with double-stranded RNA.2007

    • Author(s)
      Yoshida H, Imaizumi T, Lee SJ, Tanji K, Sakaki H, Matsumiya T, Ishikawa A, Taima K, Yuzawa E, Mori F, Wakabayashi K, Kimura H, Satoh K
    • Journal Title

      Neurosci Res 58

      Pages: 199-206

    • NAID

      10024415299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Expression of retinoicacid-inducible gene-I (RIG-I) inmacrophages : possible involvement ofRIG-I in atherosclerosis2007

    • Author(s)
      Imaizumi T, Yagihashi N, Kubota K,Yoshida H, Sakaki H, Yagihashi S, KimuraH, Satoh K
    • Journal Title

      J Atheroscler Thromb 14

      Pages: 51-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Listeria monocytogenes induces the expression of retinoic acid-inducible gene-I.2006

    • Author(s)
      Imaizumi T, Sashinami H, Mori F, Matsumiya T, Yoshida H, Nakane A, Wakabayashi K, Oyama C, Satoh K
    • Journal Title

      Microbiol Immunol 50(10)

      Pages: 811-815

    • NAID

      10020554990

    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] RIG-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines.2006

    • Author(s)
      Siren J, Imaizumi T, Sarker D, Pietila T, Noah DL, Lin R, Hiscott J, Krug RM, Fisher PB, Julknen I, Matikainen S
    • Journal Title

      Microbes Infect 8(8)

      Pages: 2013-2020

    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Retinoic acid-inducible gene-I isinduced in gingival fibroblasts by LPS orpoly IC : possible roles in interleukin-1β,-6 and -8 expression2006

    • Author(s)
      Kubota K, Sakaki H, Imaizumi T, Nakagawa H, Kusumi A, Kobayashi W, Satoh K, Kimura H
    • Journal Title

      Oral Microbiol Immunol 21

      Pages: 399-406

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] RIG-Iand mda-5 are involved in influenza Avirus-induced expression of antiviralcytokines2006

    • Author(s)
      Siren J, Imaizumi T, Sarker D, Pietila T, Noah D L, Lin R, Hiscott J, Krug RM,Fisher PB, Julknen I, Matikainen S
    • Journal Title

      Microbes Infect 8

      Pages: 2013-2020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Retinoic acid-inducible gene-I is induced in gingival fibroblasts by LPS or poly IC : possible roles in interleukin-1β, -6 and -8 expression2006

    • Author(s)
      Kubota K, Sakaki H, Imaizumi T, Nakagawa H, Kusumi A, Kobayashi W, Satoh K, Kimura H
    • Journal Title

      Oral Microbiol Immunol 21(6)

      Pages: 399-406

    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Expression of IP-10/CXCL10 is upregulated by double-stranded RNA in BEAS-2B bronchialepithelial cells2006

    • Author(s)
      Taima K, Imaizumi T, Yamashita K, Ishikawa A, Fujita T, Yoshida H, Takanashi S, Okumura K, Satoh K
    • Journal Title

      Respiration 73(3)

      Pages: 360-364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Expression of IP-10/CXCL10 is upregulated by double-stranded RNA in BEAS-2B bronchial epithelial cells.2006

    • Author(s)
      Taima K, Imaizumi T, Yamashita K, Ishikawa A, Fujita T, Yoshida H, Takanashi S, Okumura K, Satoh K
    • Journal Title

      Respiration. 73 (3)

      Pages: 360-364

    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] EB virus-encoded RNAs (EBERs)are recognized by RIG-I and activatesignaling to induce type I IFN2006

    • Author(s)
      Samanta M, Iwakiri D, Kanda T, Imaizumi T, Takada K
    • Journal Title

      EMBO J 25

      Pages: 4207-4214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Listeriamonocytogenes induces the expression ofretinoic acid-inducible gene-I2006

    • Author(s)
      Imaizumi T, Sashinami H, Mori F, Matsumiya T, Yoshida H, Nakane A, Wakabayashi K, Oyama C, Satoh K
    • Journal Title

      Microbiol Immunol 50

      Pages: 811-815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Double-stranded RNA induces the synthesis of retinoic acid-inducible gene-I in vascular endothelial cells2005

    • Author(s)
      Imaizumi T, Hatakeyama M, Yamashita K, Ishikawa A, Yoshida H, Satoh K, Taima K, Mori F, Wakabayashi K
    • Journal Title

      Endothelium 12(3)

      Pages: 133-137

    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Involvement of RIG-Iin IFN-γ/STAT1 signaling pathway inBEAS-2B cells2005

    • Author(s)
      Imaizumi T, Kumagai M, Taima K, Fujita T, Yoshida H, Satoh K
    • Journal Title

      Eur Resp J 25

      Pages: 1077-1083

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Effect of peroxisome proliferator-activated receptor-γ ligands on the expression of retinoic acid-inducible gene-I in endothelial cells stimulated with lipopolysaccharide2005

    • Author(s)
      Imaizumi T, Yamashita K, Taima K, Ishikawa A, Yoshida H, Satoh K
    • Journal Title

      Prostaglandins Other Lipid Mediat 78(1-4)

      Pages: 46-54

    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Shared and uniquefunctions of the DExD/H-box helicasesRIG-I, MDA5 and LGP2 in antiviral innateimmunity2005

    • Author(s)
      Yoneyama M, Kikuchi M, Matsumoto K, Imaizumi T, Miyagishi M, Taira K, Foy E,Loo YM, Gale Jr. M, Akira S, Yonehara S, Kato A, Fujita T
    • Journal Title

      J Immunol 175

      Pages: 2851-2858

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Journal Article] Involvement of RIG-I in IFN-γ/STAT1 signaling pathway in BEAS-2B cells.2005

    • Author(s)
      Imaizumi T, Kumagai M, Taima K, Fujita T, Yoshida H, Satoh K
    • Journal Title

      Eur Resp J 25(6)

      Pages: 1077-1083

    • Data Source
      KAKENHI-PROJECT-17590773
  • [Presentation] ヒト培養糸球体内皮細胞における抗ウイルスエフェクター蛋白20の発現と腎炎症候群の炎症病態への関与2023

    • Author(s)
      津川浩二,相澤知美,今泉忠淳,田中 完
    • Organizer
      第58回日本小児腎臓病学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07862
  • [Presentation] Orengetokuto inhibits aortic valve calcification: Confirming by animal model of SHR rat2023

    • Author(s)
      Zaiqiang Yu, Shihu Men, Kazuyuki Daitoku, Tadaatsu Imaizumi, Masahito Minakawa, Kazuhiko Seya
    • Organizer
      第53回日本心臓血管外科学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K09117
  • [Presentation] Orengedokuto inhibits TNF-α-induced HAVIC calcification obtained from calcific aortic valve stenosis patients2023

    • Author(s)
      Zaiqiang Yu, Kazuyuki Daitoku, Tadaatsu Imaizumi, Masahito Minakawa, Kazuhiko Seya
    • Organizer
      第97回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-20K09117
  • [Presentation] Inhibitory effect of CD34 on human aortic valve calcification2023

    • Author(s)
      Shihu Men, Zaiqiang Yu, Liu Xu, Kazuyuki Daitoku, Tadaatsu Imaizumi, Masahito Minakawa, Ken-Ichi Furukawa, Kazuhiko Seya
    • Organizer
      第97回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-20K09117
  • [Presentation] 糸球体内皮細胞における I型 interferon誘導遺伝子 DExD/H-Box Helicase 60の発現:ループス腎炎の病態への関与2022

    • Author(s)
      唐沢貴生,佐藤理子,藤田真司,相澤知美,津川浩二,今泉忠淳,田中 完
    • Organizer
      第57回日本小児腎臓病学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07862
  • [Presentation] 石灰化大動脈弁狭窄症患者より得た大動脈弁間質細胞はVEGFR2陽性であり、異所性石灰化に寄与する2021

    • Author(s)
      劉 旭,○于 在強, 大徳和之, 福田幾夫,元村 成, 松宮朋穂, 今泉忠淳,古川賢一, 瀬谷和彦
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19K09089
  • [Presentation] Menaquinone-4 accelerates calcification of human aortic valve interstitial cells in high-phosphate medium through PXR2020

    • Author(s)
      Kazuhiko Seya, Wei Yang, Zaiqiang Yu, Mari Chiyoya, Kazuyuki Daitoku, Shigeru Motomura, Tadaatsu Imaizumi, Ikuo Fukuda, Ken-Ichi Furukawa
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19K09089
  • [Presentation] クロロキンはヒト培養糸球体内皮細胞で TLR3を介する plasminogen activator inhibitor-1の発現を抑制する2018

    • Author(s)
      相澤知美,渡邊祥二郎,津川浩二,敦賀和志,今泉忠淳,田中 完
    • Organizer
      第53回日本小児腎臓病学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K10055
  • [Presentation] ヒト培養糸球体内皮細胞における TLR3を起点とする好中球遊走・接着因子の発現2018

    • Author(s)
      田中 完,相澤知美,渡邊祥二郎,津川浩二,敦賀和志,城 謙輔,今泉忠淳
    • Organizer
      第53回日本小児腎臓病学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K10055
  • [Presentation] 慢性炎症、動脈硬化、自然免疫、そして腎疾患2015

    • Author(s)
      今泉忠淳
    • Organizer
      第25回東北小児腎臓病研究会
    • Place of Presentation
      弘前市
    • Year and Date
      2015-03-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461204
  • [Presentation] Biphasic STAT1 phosphorylation in response to double-stranded RNA2013

    • Author(s)
      Matsumiya T, Dempoya J, Xing F, Hayakari R, Imaizumi T, Yoshida H, Satoh K
    • Organizer
      Immunology 2013, American Association of Immunologists Annual Meeting
    • Place of Presentation
      Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-23590560
  • [Presentation] Biphasic STAT1 phosphorylation in response to double-stranded RNA2013

    • Author(s)
      Matsumiya T, Dempoya J, Xing F, Hayakari R, Imaizumi T, Yoshida H, Satoh K
    • Organizer
      Immunology 2013
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-23590560
  • [Presentation] Multi-step regulation of STAT1 phosphorylation in response to double-stranded RNA2013

    • Author(s)
      Matsumiya T, Dempoya J, Xing F, Hayakari R, Yoshida H, Imaizumi T
    • Organizer
      15th International Congress of Immunology
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-23590560
  • [Presentation] Multi-step regulation of STAT1 phosphorylation in response to double-stranded RNA2013

    • Author(s)
      Matsumiya T, Dempoya J, Xing F, Hayakari R, Yoshida H, Imaizumi T
    • Organizer
      15th International congress of immnology
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-23590560
  • [Presentation] Involvement of neuronal differentiation in intracellular antiviral responses.2012

    • Author(s)
      Tomoh Matsumiya, Ryo Hayakari, Tadaatsu Imaizumi and Hidemi Yoshida
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Data Source
      KAKENHI-PROJECT-23590560
  • [Presentation] Involvement of neuronal differentiation in intracellular antiviral responses2012

    • Author(s)
      Matsumiya T, Hayakari R, Imaizumi T, Yoshida H
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-23590560
  • [Presentation] HuR regulates synergistic induction of CX3CL1 by TNF-alpha and IFN-gamma in vascular endothelial cells.2010

    • Author(s)
      Matsumiya T, Imaizumi T, Yoshida H,Satoh K
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe Japan
    • Year and Date
      2010-08-24
    • Data Source
      KAKENHI-PROJECT-20591934
  • [Presentation] 培養ヒトメサンギウム細胞における retinoic acid-inducible gene-I の発現と CCL5 : RANTES の制御2010

    • Author(s)
      田中 完,敦賀和志,沖 栄真,相澤知美,今泉忠淳
    • Organizer
      第45回日本小児腎臓病学会学術集会
    • Place of Presentation
      大阪市
    • Data Source
      KAKENHI-PROJECT-22591175
  • [Presentation] Heat shock protein 90 protects degradation of retinoic acid-inducible gene-I.2009

    • Author(s)
      Matsumiya T, Imaizumi T, Yoshida H, Topham MK, Stafforini DM, Satoh K
    • Organizer
      96^<th> Annual meeting of the American Association of Immunologist.
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2009-05-11
    • Data Source
      KAKENHI-PROJECT-20591934
  • [Presentation] 関節リウマチにおけるretinoic acid-inducible gene-I (RIG-I)の意義2008

    • Author(s)
      今泉忠淳
    • Organizer
      弘前医学会総会
    • Place of Presentation
      弘前市
    • Year and Date
      2008-06-15
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Presentation] 関節リウマチにおけるretlnoic acld-inducible gene-I (RIG-1)の意義2008

    • Author(s)
      今泉忠淳、上里涼子、吉田秀見、松宮朋穂、太田健、藤哲、佐藤敬
    • Organizer
      第92回弘前医学会総会
    • Place of Presentation
      弘前市
    • Year and Date
      2008-06-15
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Presentation] Listeria monocytogenesinduces the expression of retinoicacid-inducible gene-I2006

    • Author(s)
      今泉忠淳
    • Organizer
      International Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      京都市
    • Year and Date
      2006-06-21
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Presentation] 免疫応答・炎症反応を制御する新しい因子retinoic acid-induciblegene-I (RIG-I)2006

    • Author(s)
      今泉忠淳
    • Organizer
      弘前大学遺伝子実験施設シンポジウム
    • Place of Presentation
      弘前大学
    • Year and Date
      2006-06-30
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Presentation] Double-stranded RNA inducesthe expression of retinoic acid-inducible gene-I in culturedastrocytes2006

    • Author(s)
      今泉忠淳
    • Organizer
      International Conference of Neuroimmunology
    • Place of Presentation
      名古屋市
    • Year and Date
      2006-10-18
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Presentation] BEAS-2B 気道上皮細胞における IFN-γ/STAT1 へのRIG-I の関与2005

    • Author(s)
      今泉忠淳
    • Organizer
      日本生化学会
    • Place of Presentation
      神戸市
    • Year and Date
      2005-10-20
    • Data Source
      KAKENHI-PROJECT-17590773
  • [Presentation] 培養ヒトメサンギウム細胞において tumor necrosis factor (TNF)-αは自然免疫系を介する炎症を相乗的に増悪させる - 慢性疾患は腎炎発症のリスク因子となり得る

    • Author(s)
      田中 完,相澤知美,渡邊祥二郎,沖 栄真,津川浩二,敦賀和志,今泉忠淳
    • Organizer
      第59回日本小児腎臓病会学術集会
    • Place of Presentation
      秋田ビューホテル (秋田県秋田市)
    • Year and Date
      2014-06-05 – 2014-06-07
    • Data Source
      KAKENHI-PROJECT-25461615
  • [Presentation] IgA 免疫複合体沈着型腎炎症候群の尿沈査細胞から得られる炎症関連分子群 mRNA の検討:ウイルス感染症との関わり

    • Author(s)
      敦賀和志、渡邉祥二郎、相澤知美、吉田秀見、今泉忠淳、田中完
    • Organizer
      第23回東北小児腎臓病研究会
    • Place of Presentation
      新潟市
    • Data Source
      KAKENHI-PROJECT-21591259
  • [Presentation] 腎糸球体疾患の非侵襲的診断法開発の試み:尿中 MCP-1、fractalkine は病勢を反映するか?

    • Author(s)
      相澤知美、伊東竜也、渡邉祥二郎、敦賀和志、今泉忠淳、田中 完、伊藤悦朗
    • Organizer
      第75回腎懇話会
    • Place of Presentation
      弘前市
    • Data Source
      KAKENHI-PROJECT-25461204
  • [Presentation] Cell differentiation modulates intracellular antiviral responses in neuronal cells

    • Author(s)
      Matsumiya T, Hayakari R, Xing F, Yoshida H, Imaizumi T.
    • Organizer
      12th International Congress of Neuroimmunology
    • Place of Presentation
      Mainz, Germany
    • Year and Date
      2014-11-09 – 2014-11-13
    • Data Source
      KAKENHI-PROJECT-26460567
  • 1.  YOSHIDA Hidemi (40201008)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 75 results
  • 2.  SATOH Kei (20125438)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 58 results
  • 3.  TANAKA Hiroshi (50271820)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 46 results
  • 4.  MATSUMIYA Tomoh (30344592)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 58 results
  • 5.  Seya Kazuhiko (40281919)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 12 results
  • 6.  Yu Zaiqiang (40624268)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 11 results
  • 7.  Daitoku Kazuyuki (50374822)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 11 results
  • 8.  SHIMADA Michiko (40463765)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 9.  TANJI Kunikazu (10271800)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 10.  WAKABAYASHI Koichi (50240768)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 11.  ISHIGURO You (10312498)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  ISHIBASHI Yasuyuki (80292142)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 13.  WADA Ryuichi (20260408)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 14.  YAJIMA Nobuhisa (30443980)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  SATO Tsugumi (40733001)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  MORI Fumiaki (60200383)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  TOMIYAMA Masahiko (40311542)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  早狩 誠 (80156421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  高梨 信吾 (10187982)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  亀井 克彦 (10214545)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  渡邊 祥二郎 (80597196)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 22.  福田 幾夫 (50344594)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 23.  津川 浩二 (10447112)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 24.  皆川 正仁 (50374830)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 25.  NARITA Ikuyo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  FUKUSHI Yasuyo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  SASAKI Eiji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  伊東 健
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  佐藤 拓己
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  三村 純正
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  三木 康生
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  古川 賢一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  敦賀 和志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 34.  村上 学
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  石橋 恭太
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  城 謙輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  植草 義徳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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