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KIRIHARA Yumiko  桐原 由美子

ORCIDConnect your ORCID iD *help
Researcher Number 90234400
Other IDs
Affiliation (based on the past Project Information) *help 2018 – 2021: 島根大学, 学術研究院医学・看護学系, 助手
2016 – 2017: 島根大学, 総合科学研究支援センター, 助手
2014: 島根大学, 総合科学研究支援センター, 助手
2014: 島根大学, 医学部, 助手
2012 – 2013: 島根大学, 医学部, 教務職員 … More
2003 – 2005: SHIMANE UNIVERSITY, FACULTY OF MEDICINE, TECHNICIAN, 医学部, 教務職員
1995 – 2002: Shimane medical University, Anesthesiology, Research staff, 医学部, 教務職員
1994: 島根医科大学, 医学部, 教務員 Less
Review Section/Research Field
Principal Investigator
Anesthesiology/Resuscitation studies
Except Principal Investigator
Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Applied animal science / Anesthesiology
Keywords
Principal Investigator
モルヒネ / 一酸化窒素 / 耐性 / 脊髄 / morphine / NO / tolerance / spinal / 脊椎麻酔 / 局所麻酔薬 … More / 神経毒性 / テトラカイン / リドカイン / エピネフリン / フェニレフリン / 硬膜外麻酔 / 神経障害 / 血管収縮薬 / spinal anesthesia / local anesthetic / neurotoxicity / lidocaine / tetracaine / epinephrine / phenylephrine / epidural anesthesia / 神経因性疼痛 / オピオイド / くも膜下投与 / 痛覚過敏 / 侵害性刺激 / 非侵害性刺激 / neuropathic pain / opioid / intrathecal administration / hyperalgesia / noxious stimulus / non-noxious stimulus … More
Except Principal Investigator
モルヒネ / 脊髄 / 耐性 / グルタミン酸 / オピオイド / プロスタグランディン / アロディニア / 知覚過敏 / nitric oxide / 脊髄後角細胞 / spinal cord / 硬膜外投与 / 体性痛 / 内臓痛 / 硬膜外鎮痛 / GABA / 疼痛伝達 / 中脳水道周囲灰白質 / パイエル板 / 神経線維 / M細胞 / 免疫組織化学 / 走査電子顕微鏡 / 光学顕微鏡 / ラット / 高分子物質吸収 / 免疫組織化学的染色 / がん性疼痛 / オープンフィールド / 明暗テスト / 社交性テスト / QOL / QOL / オープンフィールドテスト / 疼痛過敏 / Prostaglandin / Hyperalgesia / Allodynia / プロスタグランデイン / 一酸化窒素 / 受容野 / プロスタグランディンF_<2α> / 痛覚過敏 / prostaglandin / hypersensitivity / 侵害性刺激 / 非侵害性刺激 / MEDシステム / 侵害刺激 / 非侵害刺激 / morphine / tolerance / noxious stimuli / non-noxious stimuli / MED system / 術後痛 / モルヒネ耐性 / 脊髄後角 / post-operative pain / morphine tolerance / spinal dorsal horn / 局所麻酔薬 / 脊髄くも膜下麻酔 / ブピバカイン / レボブピバカイン / 硬膜外麻酔 / リドカイン / 脊椎麻酔 / spinal anesthesia / neurotoxicity / local anesthetic / epidural anesthesia / lidocaine / bupivacaine / myelinated fiber / unmylelinated fiber / 交差耐性 / オキシコドン / レミフェンタニル / オピイオド / がん疼痛 Less
  • Research Projects

    (14 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (18 People)
  •  Elucidation of Opioid Cross-Tolerance in Cancer Pain Models

    • Principal Investigator
      Saito Yoji
    • Project Period (FY)
      2016 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      Shimane University
  •  Prognisis after anaogesic treatment for cancer pain

    • Principal Investigator
      SAITO Yoji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Shimane University
  •  ラット回腸パイエル板の構造と神経との関係:特に高分子蛋白物質吸収との関係

    • Principal Investigator
      権田 辰夫
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied animal science
    • Research Institution
      Shimane University
      Shimane Medical University
  •  Local anesthetic toxicity : differential neurotoxic effects among nerve fibers

    • Principal Investigator
      SAKURA Shinichi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Shimane University
      Shimane Medical University
  •  A study of effects of morphine tolerance on spinal cord in the rat incisional pain model

    • Principal Investigator
      KOSHIZAKI Masayuki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      SHIMANE UNIVERSITY FACULTY OF MEDICINE
      Shimane Medical University
  •  Effects of morphine administration on the rat neuropathic pain modelPrincipal Investigator

    • Principal Investigator
      KIRIHARA Yumiko
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Shimane University
      Shimane Medical University
  •  Study of morphine tolerance at spinal level-approach to spinal plasticity-

    • Principal Investigator
      SAITO Yoji
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Shimane Medical University
  •  脊髄疼痛伝達の神経制御回路に関する研究

    • Principal Investigator
      斉藤 洋司
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Shimane Medical University
  •  脊髄過敏形成と興奮性、抑制性神経伝達物質の変化に関する研究

    • Principal Investigator
      HASHIMOTO Keishi
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Shimane Medical University
  •  Local anesthetic neurotoxicity : Mechanisms and preventionPrincipal Investigator

    • Principal Investigator
      KIRIHARA Yumiko, 角 真理子
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Shimane Medical University
  •  硬膜外モルヒネにおける耐性形成の解明

    • Principal Investigator
      SAITO Yoji
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Shimane Medical University
  •  Role of prostaglandins and nitric oxide in the spinal plasticity

    • Principal Investigator
      SAITO Yoji
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Shimane Medical University
  •  Modulation of the development of tolerance to morphine by NOSIPrincipal Investigator

    • Principal Investigator
      KIRIHARA Yumiko
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Shimane Medical University
  •  Role of prostaglandins on sensory transduction

    • Principal Investigator
      SAITO Yoji
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Shimane Medical University

All 2012 2005 Other

All Journal Article Presentation

  • [Journal Article] The comparative neurotoxicity of intrathecal lidocaine and bupivacaine in rats2005

    • Author(s)
      Sakura S, Kirihara Y, Muguruma T, Kishimoto T, Saito Y.
    • Journal Title

      Anesthesia and Analgesia 101, 2

      Pages: 541-547

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591630
  • [Journal Article] Comparative somatic and visceral antinociception and neurotoxicity of intrathecal bupivacaine, levobupivacaine, and dextrobupivacaine in rats

    • Author(s)
      Muguruma T, Sakura S, Kirihara Y, Saito Y.
    • Journal Title

      Anesthesiology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591630
  • [Presentation] STUDY OF BONE CANCER PAIN MODEL IN MICE: COMPARISON BY STRAIN AND SEX2012

    • Author(s)
      1. Yumiko Kirihara, 2. Mayumi Takechi, 3. Kaoru Kurosaki, 4. Yuta Kobayashi and 5. Yoji Saito
    • Organizer
      世界疼痛学会
    • Place of Presentation
      ミラノ(イタリア)
    • Data Source
      KAKENHI-PROJECT-24592296
  • 1.  SAITO Yoji (50162243)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 1 results
  • 2.  DOI Katsusi (20304272)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  KOSIZAKI Masayuki (40294376)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  HASHIMOTO Keishi (60252920)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  HASHIMOTO Tatsuya (00372681)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  NAKATANI Toshihiko (90237305)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  SAKURA Shinichi (80170637)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 8.  UCHIDA Hiroshi (70176692)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  YAMAMORI Yuji (80230598)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  原 かおる (50271052)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  山中 真波 (30304281)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  権田 辰夫 (40116398)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  竹内 崇師 (10325061)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  柳谷 忠雄 (10243429)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  角 真理子 (70252939)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  宮本 寛 (20297005)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  岸本 朋宗 (50284039)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  森 英明 (40713764)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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