KIRIHARA Yumiko 桐原由美子

Researcher Number	90234400
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2021: 島根大学, 学術研究院医学・看護学系, 助手 2016 – 2017: 島根大学, 総合科学研究支援センター, 助手 2014: 島根大学, 総合科学研究支援センター, 助手 2014: 島根大学, 医学部, 助手 2012 – 2013: 島根大学, 医学部, 教務職員 … More 2003 – 2005: SHIMANE UNIVERSITY, FACULTY OF MEDICINE, TECHNICIAN, 医学部, 教務職員 1995 – 2002: Shimane medical University, Anesthesiology, Research staff, 医学部, 教務職員 1994: 島根医科大学, 医学部, 教務員 Less
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies Except Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Applied animal science / Anesthesiology
Keywords	Principal Investigator モルヒネ / 一酸化窒素 / 耐性 / 脊髄 / morphine / NO / tolerance / spinal / 脊椎麻酔 / 局所麻酔薬 … More / 神経毒性 / テトラカイン / リドカイン / エピネフリン / フェニレフリン / 硬膜外麻酔 / 神経障害 / 血管収縮薬 / spinal anesthesia / local anesthetic / neurotoxicity / lidocaine / tetracaine / epinephrine / phenylephrine / epidural anesthesia / 神経因性疼痛 / オピオイド / くも膜下投与 / 痛覚過敏 / 侵害性刺激 / 非侵害性刺激 / neuropathic pain / opioid / intrathecal administration / hyperalgesia / noxious stimulus / non-noxious stimulus … More Except Principal Investigator モルヒネ / 脊髄 / 耐性 / グルタミン酸 / オピオイド / プロスタグランディン / アロディニア / 知覚過敏 / nitric oxide / 脊髄後角細胞 / spinal cord / 硬膜外投与 / 体性痛 / 内臓痛 / 硬膜外鎮痛 / GABA / 疼痛伝達 / 中脳水道周囲灰白質 / パイエル板 / 神経線維 / M細胞 / 免疫組織化学 / 走査電子顕微鏡 / 光学顕微鏡 / ラット / 高分子物質吸収 / 免疫組織化学的染色 / がん性疼痛 / オープンフィールド / 明暗テスト / 社交性テスト / QOL / ＱＯＬ / オープンフィールドテスト / 疼痛過敏 / Prostaglandin / Hyperalgesia / Allodynia / プロスタグランデイン / 一酸化窒素 / 受容野 / プロスタグランディンF_<2α> / 痛覚過敏 / prostaglandin / hypersensitivity / 侵害性刺激 / 非侵害性刺激 / MEDシステム / 侵害刺激 / 非侵害刺激 / morphine / tolerance / noxious stimuli / non-noxious stimuli / MED system / 術後痛 / モルヒネ耐性 / 脊髄後角 / post-operative pain / morphine tolerance / spinal dorsal horn / 局所麻酔薬 / 脊髄くも膜下麻酔 / ブピバカイン / レボブピバカイン / 硬膜外麻酔 / リドカイン / 脊椎麻酔 / spinal anesthesia / neurotoxicity / local anesthetic / epidural anesthesia / lidocaine / bupivacaine / myelinated fiber / unmylelinated fiber / 交差耐性 / オキシコドン / レミフェンタニル / オピイオド / がん疼痛 Less

Elucidation of Opioid Cross-Tolerance in Cancer Pain Models
- Principal Investigator
  
  Saito Yoji
- Project Period (FY)
  2016 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Shimane University
Prognisis after anaogesic treatment for cancer pain
- Principal Investigator
  
  SAITO Yoji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Shimane University
ラット回腸パイエル板の構造と神経との関係:特に高分子蛋白物質吸収との関係
- Principal Investigator
  
  権田辰夫
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied animal science
- Research Institution
  Shimane University
  Shimane Medical University
Local anesthetic toxicity : differential neurotoxic effects among nerve fibers
- Principal Investigator
  
  SAKURA Shinichi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Shimane University
  Shimane Medical University
A study of effects of morphine tolerance on spinal cord in the rat incisional pain model
- Principal Investigator
  
  KOSHIZAKI Masayuki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  SHIMANE UNIVERSITY FACULTY OF MEDICINE
  Shimane Medical University
Effects of morphine administration on the rat neuropathic pain modelPrincipal Investigator
- Principal Investigator
  
  KIRIHARA Yumiko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Shimane University
  Shimane Medical University
Study of morphine tolerance at spinal level-approach to spinal plasticity-
- Principal Investigator
  
  SAITO Yoji
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Shimane Medical University
脊髄疼痛伝達の神経制御回路に関する研究
- Principal Investigator
  
  斉藤洋司
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Shimane Medical University
脊髄過敏形成と興奮性、抑制性神経伝達物質の変化に関する研究
- Principal Investigator
  
  HASHIMOTO Keishi
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Shimane Medical University
Local anesthetic neurotoxicity : Mechanisms and preventionPrincipal Investigator
- Principal Investigator
  
  KIRIHARA Yumiko, 角真理子
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Shimane Medical University
硬膜外モルヒネにおける耐性形成の解明
- Principal Investigator
  
  SAITO Yoji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Shimane Medical University
Role of prostaglandins and nitric oxide in the spinal plasticity
- Principal Investigator
  
  SAITO Yoji
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Shimane Medical University
Modulation of the development of tolerance to morphine by NOSIPrincipal Investigator
- Principal Investigator
  
  KIRIHARA Yumiko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Shimane Medical University
Role of prostaglandins on sensory transduction
- Principal Investigator
  
  SAITO Yoji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Shimane Medical University

All 2012 2005 Other

All Journal Article Presentation

[Journal Article] The comparative neurotoxicity of intrathecal lidocaine and bupivacaine in rats2005
- Author(s)
  Sakura S, Kirihara Y, Muguruma T, Kishimoto T, Saito Y.
- Journal Title
  
  Anesthesia and Analgesia 101, 2
  
  Pages: 541-547
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591630
[Journal Article] Comparative somatic and visceral antinociception and neurotoxicity of intrathecal bupivacaine, levobupivacaine, and dextrobupivacaine in rats
- Author(s)
  Muguruma T, Sakura S, Kirihara Y, Saito Y.
- Journal Title
  
  Anesthesiology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591630
[Presentation] STUDY OF BONE CANCER PAIN MODEL IN MICE: COMPARISON BY STRAIN AND SEX2012
- Author(s)
  1. Yumiko Kirihara, 2. Mayumi Takechi, 3. Kaoru Kurosaki, 4. Yuta Kobayashi and 5. Yoji Saito
- Organizer
  世界疼痛学会
- Place of Presentation
  ミラノ（イタリア）
- Data Source
  KAKENHI-PROJECT-24592296

1. SAITO Yoji (50162243)

# of Collaborated Projects: 11 results

# of Collaborated Products: 1 results
2. DOI Katsusi (20304272)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KOSIZAKI Masayuki (40294376)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HASHIMOTO Keishi (60252920)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. HASHIMOTO Tatsuya (00372681)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NAKATANI Toshihiko (90237305)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SAKURA Shinichi (80170637)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. UCHIDA Hiroshi (70176692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YAMAMORI Yuji (80230598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 原かおる (50271052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 山中真波 (30304281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 権田辰夫 (40116398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 竹内崇師 (10325061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 柳谷忠雄 (10243429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 角真理子 (70252939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 宮本寛 (20297005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 岸本朋宗 (50284039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 森英明 (40713764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KIRIHARA Yumiko 桐原 由美子

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Effects of morphine administration on the rat neuropathic pain modelPrincipal Investigator

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Local anesthetic neurotoxicity : Mechanisms and preventionPrincipal Investigator

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Modulation of the development of tolerance to morphine by NOSIPrincipal Investigator

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[Journal Article] The comparative neurotoxicity of intrathecal lidocaine and bupivacaine in rats2005

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KIRIHARA Yumiko 桐原由美子