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Yasumoto Ken-ichi  安元 研一

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YASUMOTO Kenichi  安元 研一

YASUMOTO Ken-ichi  安元 研一

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Researcher Number 90241629
Other IDs
External Links
Affiliation (Current) 2025: 東北大学, 生命科学研究科, 准教授
Affiliation (based on the past Project Information) *help 2016: 東北大学, 生命科学研究科, 准教授
2007: Tohoku University, Graduate School of Life Sciences, Associate Professor
2005 – 2006: Tohoku University, Graduate School of Life Sciences, Associate Professor, 大学院生命科学研究科, 助教授
2005: 東北大学, 大学院・生命科学研究科, 教授
2003 – 2005: 東北大学, 大学院・生命科学研究科, 助教授
1999 – 2000: School of Medicine, Tohoku University, Research Associate, 大学院・医学系研究科, 助手
1994 – 1998: 東北大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Biological Sciences / Pathological medical chemistry / General medical chemistry
Except Principal Investigator
Pathological medical chemistry / Biological Sciences / Functional biochemistry / Nerve anatomy/Neuropathology / Pediatric surgery
Keywords
Principal Investigator
TRP-2 / transcriptional regulation / microphthalmia / gene expression / tyrosinase / MITF / melanin / Waardenburg syndrome / CYP1A2 / LBP-1 … More / AhR / FLIM-FRET / 蛍光顕微鏡 / 遺伝子調節 / 転写因子 / 薬物応答 / Wnt / LEF-1 / DOPAchrome tautomerase / Arnt / 転写因子複合体 / melnin / MIFT / gene expession … More
Except Principal Investigator
transcription factor / 転写因子 / FLIM-FRET / チロシナーゼ / タンパク間相互作用 / VBC複合体 / FRET / pVHL / Elongin C / Elongin B / protein-protein interaction / FLIM / melanin / TRP-2 / TRP-1 / メラニン / cell differentiation / tyrosinase / MITF / 細胞分化 / LBP-1 / CYP1A2 / ヘムオキシゲナーゼ / メラノサイト / MPTP / 神経変性疾患 / Parkin / PINK1 / パーキンソン病 / リン酸化 / Parkin / PINK1 / IPAS / Protein-protein interaction / Conformation Change / ストレス応答 / コンフォメーション変化 / VBC complex / living cells / Transcription factor / FRET-FLIM / Living cell / YFP / CFP / FRIM-FRET / in vivo計測 / von Hippel-Linda / Elongin / 生細胞 / retina / melanocyte / 網膜 / microphthalmia / tyosinase / TRF-2 / TRF-1 / 小眼球症 / heme oxygenase / heme catabolism / melanin biosynthesis / ヘム分解 / メラニン合成 / Ahリセプター / タンパクータンパク相互作用 / ダイマー形成 / Arnt / LBP-1タンパク質 / 蛋白質 / 可視化 / 核移行シグナル / ヘテロダイマー / C-Kit / ヒト結腸 / Sox 10 / MITFアイソフォーム / c-kit / アドレノメデュリン / チロシナーゼ関連タンパク Less
  • Research Projects

    (19 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (11 People)
  •  Elucidation of pathogenic mechanism of Parkinson's disease through analysis of IPAS, a novel substrate of Parkin

    • Principal Investigator
      Torii Satoru
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Tokyo Medical and Dental University
  •  生細胞でのAhリセプター転写複合体のイメージングと活性化機構

    • Principal Investigator
      十川 和博
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  外来薬物による遺伝子発現誘導における転写因子複合体の機能解析Principal Investigator

    • Principal Investigator
      安元 研一
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Visualization of the VBC complex in living cells by FLIM-FRET

    • Principal Investigator
      SOGAWA Kazuhiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tohoku University
  •  発がん物質による転写活性化過程の単一生細胞内イメージング

    • Principal Investigator
      SOGAWA Kazuhiro
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  FRETによる単一生細胞でのPMLボディ生理機能の可視化

    • Principal Investigator
      十川 和博
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  FLIM-FRET測定とRNAiを用いた薬物による遺伝子発現誘導機構の解析Principal Investigator

    • Principal Investigator
      安元 研一
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Real-time observation of interactions between trancription factors containing PAS domains

    • Principal Investigator
      SOGAWA Kazuhiro
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tohoku University
  •  色素細胞分化におけるWntシグナル関連因子とMITFとの機能的相互作用Principal Investigator

    • Principal Investigator
      安元 研一
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  小眼球症関連転写因子による細胞分化と形質発現の制御機構Principal Investigator

    • Principal Investigator
      安元 研一
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  小眼球症関連転写因子MITFの細胞分化における機能的多様性Principal Investigator

    • Principal Investigator
      安元 研一
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  腸管筋層における転写因子MITF isoformによるC-KIT発現調節

    • Principal Investigator
      大井 龍司
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatric surgery
    • Research Institution
      Tohoku University
  •  Molecular basis of the structural and functional multiplicity of microphthalmia-associated transcription factor

    • Principal Investigator
      SHIBAHARA Shigeki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      TOHOKU UNIVERSITY
  •  転写因子MITFによる色素細胞分化とメラニン生合成の制御機構の解明Principal Investigator

    • Principal Investigator
      安元 研一
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  個体老化のモデルとしての白髪形成の分子機構の解明

    • Principal Investigator
      SHIBAHARA Shigeki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  Molecular mechanisms of pigment cell differentiation.

    • Principal Investigator
      SHIBAHARA Shigeki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  メラニン生成関連遺伝子の色素細胞特異的発現に関わる転写因子の解析Principal Investigator

    • Principal Investigator
      安元 研一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
  •  Development of a new method for detecting gene expression in a single cell and its medical application.

    • Principal Investigator
      SHIBAHARA Shigeki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  ヒトメラニン生成関連遺伝子のメラノサイト特異的転写の分子機構Principal Investigator

    • Principal Investigator
      安元 研一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University

All 2015 2007 2006

All Journal Article Presentation

  • [Journal Article] Involvement of inhibitory PAS domain protein in neuronal cell death in Parkinson’s disease2015

    • Author(s)
      Satoru Torii, Shuya Kasai, Ayako Suzuki, Yuta Todoroki, Kazuma Yokosawa, Ken-ichi Yasumoto, Hiroshi Kiyonari, Yoshiko Mukumoto, Akiyoshi Kakita, Kazuhiro Sogawa
    • Journal Title

      Cell Death Discovery

      Volume: 1 Issue: 1 Pages: 1-12

    • DOI

      10.1038/cddiscovery.2015.15

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26430051
  • [Journal Article] Identification of amino acid residues in the Ah receptor involved in ligand binding2007

    • Author(s)
      K. Goryo, A. Suzuki, C. A. Del Carpio, K. Siizaki, E. Kuriyama, Y. Mikami, K. Kinoshita, K. Yasumoto, A. Ranpug, A. Miyamoto, Y. Fujii-Kuriyama, and K. Sogawa
    • Journal Title

      Biophys. Biochem. Res. Commun. 354

      Pages: 396-402

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18370051
  • [Presentation] Evaluation of dioxins contamination using AhR as a marker of Ensitivity to dioxins-polymorphism and function of AhR in Japanese field mice, Apodemus speciosus2006

    • Author(s)
      H. Ishiniwa, K. Sogawa, K. Yasumoto, T. Sekijima
    • Organizer
      Symposium on Biological Responses and Inter/Intra Environments
    • Place of Presentation
      Fukuoka Recent Hotel
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18370051
  • 1.  SOGAWA Kazuhiro (80175421)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 3 results
  • 2.  SHIBAHARA Shigeki (70206142)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  TAKASAKI Chikahisa (10004491)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  TAKAHASHI Kazuhiro (80241628)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  FUKUMURA Hiroshi (50208980)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  KIKUCHI Yasuo (10004467)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  Torii Satoru (10444001)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  大井 龍司 (50004734)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  仁尾 正記 (70228138)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  武田 和久 (30311559)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  SHIBATA Koushi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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