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TOHTU Miki  三木 徹

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MIKI Tohru  三木 徹

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Researcher Number 90242180
Affiliation (based on the past Project Information) *help 2006: Tokyo Medical and Dental University, Postgraduate School of Medicine, Lecturer, 大学院医歯学総合研究科, 講師
2005: 東京医科歯科大学, 大学院・医歯学総合研究科, 講師
2000 – 2003: 東京医科歯科大学, 大学院・医歯学総合研究科, 講師
1994 – 1998: 東京医科歯科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Hematology / Hematology
Except Principal Investigator
Human pathology / Hematology / Hematology
Keywords
Principal Investigator
BCL6 / 悪性リンパ腫 / Malignant Lymphoma / 転写因子 / 染色体転座 / IRF4 / BAZF / Transcription factor / Plasmacytic differentiation / BLIMP1 … More / 形質細胞分化 / Transcription Factor / Acetylation / BAZ F / zinc-finger protein / 転写抑制因子 / アセチル化 / Chromosomal translocation / Science / Gene expression / malignant / 胚中心 / サイレンサー / 遺伝子発現 / 転写調節因子 … More
Except Principal Investigator
悪性リンパ腫 / 染色体転座 / Castleman's tumor / Hodgkin's disease / Human herpes virus 8 / Epstein Barr virus / malignant lymphoma / p80 / bcl6 / 分類 / 病理分類 / 染色体 / キャッスルマン腫瘍 / ホジキン病 / 8型ヘルペスウイルス / EBウイルス / チロシンリン酸化 / Lyn / Jak2 / STAT5 / 白血病 / シグナル伝達 / 造血器腫瘍 / 転写調節因子 / BCL6 / リンパ腫 / ルシフェラーゼ / プロモーター / BCL-6 / 切断点 / Zinc finger / Trans cription factor / BCL6 gene Less
  • Research Projects

    (10 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (16 People)
  •  The role of IRF4 in plasmacytic differentiationPrincipal Investigator

    • Principal Investigator
      TOHTU Miki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tokyo Medical and Dental University
  •  抗体アレイ法を応用した造血器腫瘍細胞におけるシグナル伝達因子異常の網羅的解析

    • Principal Investigator
      三浦 修
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Tokyo Medical and Dental University
  •  Functional modification of the transcription factor BCL6 by acetylationPrincipal Investigator

    • Principal Investigator
      MIKI Tohru
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      TOKYO MEDEICAL AND DENTAL UNIVERSITY
  •  THE SIGNIFICANCE OF CHROMOSOMAL TRANSLOCATION INVOLVING BCL6 GENE IN MALIGNANT LYMPHOMAPrincipal Investigator

    • Principal Investigator
      MIKI Tohru
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      TOKYO MEDEICAL AND DENTAL UNIVERSITY
  •  Analysis for transcriptional regulation of the BCL6 genePrincipal Investigator

    • Principal Investigator
      MIKI Tohru
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tokyo Medical and Dental University
  •  B細胞リンパ腫に関与する遺伝子(BCL-6)の発癌への関与のメカニズムの研究

    • Principal Investigator
      広沢 信作
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Medical and Dental University
  •  ヒトBCL6遺伝子の発現制御の研究

    • Principal Investigator
      村上 直巳
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tokyo Medical and Dental University
  •  Remodeling of the classification of malignant lymphomas occurring among Japanese based on molecular abnormality

    • Principal Investigator
      MORI Shigeo
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Human pathology
    • Research Institution
      The University of Tokyo
  •  悪性リンパ腫関連遺伝子BCL6の過剰発現がB細胞に与える影響についてPrincipal Investigator

    • Principal Investigator
      三木 徹
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tokyo Medical and Dental University
  •  B細胞リンパ腫に関与する遺伝子(BCL-5)の同定と発症メカニズムの研究

    • Principal Investigator
      広沢 信作
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Medical and Dental University

All 2003 Other

All Journal Article

  • [Journal Article] BCL6 overexpression prevents increase in reactive oxygen species and inhibits apoptosis induced by chemotherapeutic reagents in B-cell lymphoma cells2003

    • Author(s)
      Kurosu T, Fukuda T, Miki T, Miura O.
    • Journal Title

      Oncogene 22・29

      Pages: 4459-4468

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570966
  • [Journal Article] BCL6 overexpression prevents increase in reactive oxygen species and inhibits apoptosis induced by chemotherapeutic reagents in B-cell lymphoma cells2003

    • Author(s)
      Kurosu T, Fukuda T, Miki T, Miura O.
    • Journal Title

      Oncogene 22(23)

      Pages: 4459-4468

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570966
  • [Journal Article] IRF4 negatively regulates proliferation of germinal centre B cell-derived Burkitt's lymphoma cell lines and induces differentiation toward plasma cells

    • Author(s)
      Yuou Teng, Yusuke Takahashi, Makiko Yamada, Tetsuya Kurosu, Takatoshi Koyama, Osamu Miura, Tohru Miki
    • Journal Title

      European Journal of Cell Biology (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590982
  • [Journal Article] IRF4 negatively regulates proliferation of germinal center B cell-derived Burkitt's lymphoma cell lines and induces differentiation toward plasma cells.

    • Author(s)
      Yuou Teng, Yusuke Takahashi, Makiko Yamada, Tetsuya Kurosu, Takatoshi Koyama, Osamu Miura, Tohru Miki
    • Journal Title

      European Journal of Cell Biology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590982
  • 1.  広沢 信作 (50143574)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  東田 修二 (80251510)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  鈴木 謙 (90251511)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  大橋 一輝 (90262188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  村上 直巳 (50143582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  三浦 修 (10209710)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  新井 文子 (70359678)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  山本 晃 (00281717)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MORI Shigeo (30010424)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  FUKUHARA Shiro (40142301)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  AKAGI Tadaatsu (20136386)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  ABE Masafumi (00045783)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  NAKAMURA Shigeo (80180363)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  珠玖 洋 (80154194)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  上田 龍三 (20142169)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  青笹 克之 (30115985)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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