OMAGARI Katsuhisa 大曲勝久

Researcher Number	90244045
Other IDs
External Links
Affiliation *help	2012 – 2018 : 長崎県立大学, 看護栄養学部, 教授 2008 – 2010 : University of Nagasaki, 看護栄養学部, 教授 2003 – 2005 : 長崎大学, 大学院・医歯薬学総合研究科, 講師 2002 : 長崎大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Integrated Nutrition Science / Applied pharmacology Except Principal Investigator Eating habits / Public health/Health science
Keywords	Principal Investigator 原発性胆汁性肝硬変 / enzyme inhibition assay / Western blotting / autoimmune cholangitis / フィコシアニン / SDラット / 胆汁酸のホメオスターシス / antimitochondrial antibody / 遺伝子診断 / 肝線維化 … More Except Principal Investigator 腸内細菌 / 水素ガス / 難消化性糖質 / プレバイオティクス / 重症化遅延 / 発症遅延 / 疾病発症予防 / 抗酸化作用 / 肝障害 / 老化 / プレバイオティックス / 抗酸化能 / 下痢抑制作用 Less

Correlation among the delaying effect on the onset of diseases and hydrogen produced from intestinal microbes by intake of nondigestible saccharide
- Principal Investigator
  
  Nakamura Sadako
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Jumonji University
Investigation of pathogenic mechanism of non-alcoholic steatohepatitis and nutritional treatment based on the mechanismPrincipal Investigator
- Principal Investigator
  
  OMAGARI Katsuhisa
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  University of Nagasaki
Effect on the suppression to diarrhea by hydrogen derived from the fermentation of intestinal microbes by the ingestion of nondigestible oligosaccharide.
- Principal Investigator
  
  NAKAMURA Sadako
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Public health/Health science
- Research Institution
  University of Nagasaki
Identification of primary biliary cirrhosis-susceptibility genes to the progression and its application to DNA-based diagnosisPrincipal Investigator
- Principal Investigator
  
  OMAGARI Katsuhisa
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  University of Nagasaki
Development and its application of serum marker for the evaluation of staging in primary biliary cirrhosisPrincipal Investigator
- Principal Investigator
  
  OMAGARI Katsuhisa
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagasaki University

All 2015 2014 2013 2012 2011 2010 2009 2008 2005 2003 Other

All Journal Article Presentation Book

[Book] 臨床薬理の進歩-胆汁酸の排泄に関与するABCトランスポーター多型と原発性胆汁性肝硬変の重症化との関連-2010
- Author(s)
  塚元和弘, 大曲勝久, 中村稔
- Publisher
  財団法人臨床薬理研究振興財団
- Data Source
  KAKENHI-PROJECT-20590545
[Journal Article] igh-fat and high-cholesterol diet rapidly induces non-alcoholic steatohepatitis with advanced fibrosis in Sprague-Dawley rats.2015
- Author(s)
  Ichimura M, Kawase M, Masuzumi M, Sakaki, Nagata Y, Tanaka K, Suruga K, Tamaru S, Kato S, Tsuneyama K, Omagari K
- Journal Title
  
  Hepatol Res.
  
  Volume : 45 Pages : 458-469
- DOI
  10.1111/hepr.12358
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J12556, KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24500990, KAKENHI-PROJECT-24614011
[Journal Article] An SHR/NDmcr-cp rat model of non-alcoholic steatohepatitis with advanced fibrosis induced by a high-fat, high-cholesterol diet.2015
- Author(s)
  Ichimura M, Hatanaka M, Tsuneyama K, Kato S, Omagari K
- Journal Title
  
  Journal of Obesity and Weight Loss therapy
  
  Volume : 5 Pages : 244-244
- DOI
  10.4172/2165-7904.1000244
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J12556, KAKENHI-PROJECT-24614011
[Journal Article] Abdominal subcutaneous adipose tissue accumulation is positively correlated with hepatic steatosis in Sprague-Dawley rats.2014
- Author(s)
  Katsuhisa Omagari, Chisato Yoshikawa, Shin-ichi Inoue, Yuna Tanaka, Toshie Murayama, Mayuko Ichimura, Ayako Miyata, Sawako Mori, Mai Kamogawa, Eri Hirao, Shigeko Kato, Kazuhito Suruga, Koichi Tsuneyama
- Journal Title
  
  Acta Medica Nagasakiensia
  
  Volume : 59 Pages : 47-56
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24614011
[Journal Article] Phycocyanin prevents hypertension and low serum adiponectin level in a rat model of metabolic syndrome.2013
- Author(s)
  Ichimura M, Kato S, Tsuneyama K, et al.
- Journal Title
  
  Nutr Res
  
  Volume : (In press) Pages : 397-405
- DOI
  10.1016/j.nutres.2013.03.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24614011
[Journal Article] ヒトにおけるダイフルクトースアンハイドライトIIIおよびマンニトールの一過性下痢に対する最大無作用量の評価2012
- Author(s)
  中村禎子,田辺賢一,大曲勝久,奥恒行
- Journal Title
  
  New Diet Therapy
  
  Volume : 28 Pages : 3-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590599
[Journal Article] A polymorphism in the integrin αV subunit gene affects the progression of primary biliary cirrhosis in Japanese patients.2011
- Author(s)
  Inamine T, Tsukamoto K., Omagari K, et al.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume : 46 Pages : 676-686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590545
[Journal Article] 胆汁酸の排泄に関与するABCトランスポーター多型と原発性胆汁性肝硬変の重症化との関連2010
- Author(s)
  塚元和弘, 大曲勝久, 中村稔
- Journal Title
  
  臨床薬理の進歩 31
  
  Pages : 73-86
- Data Source
  KAKENHI-PROJECT-20590545
[Journal Article] Single-nucleotide polymorphism analysis of the multidrug resistance protein 3 gene for the detection of clinical progression in Japanese patients with primary biliary cirrhosis.2008
- Author(s)
  Ohishi Y, Tsukamoto K, Omagari K, et al.
- Journal Title
  
  Hepatology 48
  
  Pages : 853-862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590545
[Journal Article] Single-nucleotide polymorphism analysis of the multidrug resistance protein 3 gene for the detection of clinical progression in Japanese patients with primary biliary cirrhosis.2008
- Author(s)
  Ohishi Y, Omagari K, Tsukamoto K, et al.
- Journal Title
  
  Hepatology 48
  
  Pages : 853-862
- Data Source
  KAKENHI-PROJECT-20590545
[Journal Article] Reconsideration of autoimmune cholangitis2005
- Author(s)
  Omagari K, et al.
- Journal Title
  
  Clinics in Gastroenterology, (in Japanese) 8-6
  
  Pages : 724-732
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570481
[Journal Article] How many patients with primary biliary cirrhosis are there in Japan?2005
- Author(s)
  Omagari K, et al.
- Journal Title
  
  Clinics in Gastroenterology, (in Japanese) 8-2
  
  Pages : 238-244
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570481
[Journal Article] 日本人のPBC患者はどれくらいいいるのか?2005
- Author(s)
  大曲勝久, 他
- Journal Title
  
  消火器の臨床 (In press)
- Data Source
  KAKENHI-PROJECT-14570481
[Journal Article] 再考・自己免疫性胆管炎2005
- Author(s)
  大曲勝久・他
- Journal Title
  
  消化器の臨床 8巻6号
  
  Pages : 724-732
- Data Source
  KAKENHI-PROJECT-14570481
[Journal Article] 再考・自己免疫性胆管炎2005
- Author(s)
  大曲勝久・他
- Journal Title
  
  消化器の臨床 8巻6号
  
  Pages : 724-732
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570481
[Journal Article] 日本人のPBC患者はどれくらいいるのか?2005
- Author(s)
  大曲勝久・他
- Journal Title
  
  消化器の臨床 8巻2号
  
  Pages : 238-244
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570481
[Journal Article] Does the diagnosis of primary biliary cirrhosis or autoimmune cholangitis depend on the 'phase' of the disease?2005
- Author(s)
  Kadokawa Y, Omagari K, et al.
- Journal Title
  
  Liver International, 25-2
  
  Pages : 317-324
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570481
[Journal Article] Evaluation of newly developed ELISA using "MESACUP-2 Test Mitochondrial M2" kit for the diagnosis of primary biliary cirrhosis2003
- Author(s)
  Kadokawa Y, Omagari K, et al.
- Journal Title
  
  Clinical Biochemistry, 36-3
  
  Pages : 203-210
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570481
[Journal Article] Clinical significance of antimitochondrial antibody by ELISA using "MESACUP-2 Test Mitochondrial M2" kit for the diagnosis of primary biliary cirrhosis2003
- Author(s)
  Omagari K, et al.
- Journal Title
  
  Japanese Journal of Medicine and Pharmaceutical Science, (in Japanese) 50-4
  
  Pages : 543-550
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570481
[Journal Article] 原発性胆汁性肝硬変の経過観察における「MESACUP-2 テストミトコンドリアM2」測定の臨床的意義 -蛍光抗体間接法との比較検討-2003
- Author(s)
  大曲勝久, 他
- Journal Title
  
  医学と薬学 50巻4号
  
  Pages : 543-550
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570481
[Journal Article] Correlation between histopathological findings of the liver and IgA class Antibodies to 2-oxo-acid dehydrogenase complex in primary biliary cirrhosis2003
- Author(s)
  Masuda J, Omagari K, et al.
- Journal Title
  
  Digestive Diseases and Sciences, 48-5
  
  Pages : 932-938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570481
[Journal Article] Enzyme inhibition assay for pyruvate dehydrogenase complex : Clinical utility for the diagnosis of primary biliary cirrhosis
- Author(s)
  Omagari K, et al.
- Journal Title
  
  World Journal of Gastroenterology, (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570481
[Journal Article] Enzyme inhibition assay for pyruvate dehydrogenase complex : Clinical utility for the diagnosis of primary biliary cirrhosis
- Author(s)
  Omagari K, et al.
- Journal Title
  
  World Journal of Gastroenterology (in press)
- Data Source
  KAKENHI-PROJECT-14570481
[Journal Article] A polymorphism in the integrin αV subunit gene affects the progression of primary biliary cirrhosis in Japanese patients.
- Author(s)
  Inamine T, Omagari K, Tsukamoto K, et al.
- Journal Title
  
  J Gastroenterology in press
- Data Source
  KAKENHI-PROJECT-20590545
[Journal Article] Enzyme inhibition assay for pyruvate dehydrogenase complex : Clinical utility for the diagnosis of primary biliary cirrhosis
- Author(s)
  Omagari K, et al.
- Journal Title
  
  World Journal of Gastroenterology (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570481
[Presentation] SDラットにおける高脂肪・高コレステロール食によるNASH肝硬変モデルの作成2014
- Author(s)
  市村真祐子、常山幸一、大曲勝久
- Organizer
  第18回日本肝臓学会大会
- Place of Presentation
  神戸国際会議場（兵庫県・神戸市）
- Year and Date
  2014-10-23
- Data Source
  KAKENHI-PROJECT-24614011
[Presentation] High-fat and high-cholesterol diet rapidly induces nonalcoholic steatohepatitis with advanced fibrosis in Sprague-Dawley rats2014
- Author(s)
  Ichimura M, Kawase M, Masuzumi M, Sakaki M, Nagata Y, Tanaka K, Suruga K, Tsuneyama K, Omagari K.
- Organizer
  23rd conference of the Asian Pacific Association for the Study of the Liver
- Place of Presentation
  Brisbane Convention & Exhibition Centre （オーストラリア・ブリスベーン）
- Data Source
  KAKENHI-PROJECT-24614011
[Presentation] Phycocyanin prevents hypertension through improving vascular dysfunction2013
- Author(s)
  Ichimura M, Hatanaka M, Ito MK, Omagari K.
- Organizer
  The 8th Japan-Korea International Nursing Conference
- Place of Presentation
  長崎県立大学シーボルト校（長崎県西彼杵郡長与町）
- Data Source
  KAKENHI-PROJECT-24614011
[Presentation] 高コレステロール・高脂肪食による高度線維化を伴うNASH動物モデルの作成2013
- Author(s)
  市村真祐子、畑中麻衣子、常山幸一、加藤滋子、大曲勝久
- Organizer
  第67回日本栄養・食糧学会大会
- Place of Presentation
  名古屋大学東山キャンパス豊田講堂（名古屋）
- Data Source
  KAKENHI-PROJECT-24614011
[Presentation] FGF遺伝子は原発性胆汁性肝硬変の重症化に関与する2011
- Author(s)
  稲嶺達夫, 塚元和弘, 大曲勝久, 他
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] ASBT遺伝子は原発性胆汁性肝硬変の進行に関与する2010
- Author(s)
  河内歩美, 塚元和弘, 大曲勝久, 他
- Organizer
  第27回日本薬学会九州支部大会
- Place of Presentation
  長崎
- Year and Date
  2010-12-11
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] FGF19遺伝子は原発性胆汁性肝硬変の重症化に関与する2010
- Author(s)
  稲嶺達夫, 大曲勝久, 塚元和弘, 他
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] ABCG5/ABCG8遺伝子は原発性胆汁性肝硬変の重症化感受性遺伝子である2010
- Author(s)
  河内歩美, 大曲勝久, 塚元和弘, 他
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] HNF-4α遺伝子は原発性胆汁性肝硬変の重症化感受性遺伝子である2009
- Author(s)
  野口扶美枝, 大曲勝久, 塚元和弘, 他
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] CYP7A1遺伝子は原発性胆汁性肝硬変の疾患抵抗性遺伝子である2009
- Author(s)
  比嘉辰伍, 大曲勝久, 塚元和弘, 他
- Organizer
  第17回医療薬学フォーラム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] Diplotype polymorphisms of the salt export pump gene are associated with susceptibility to the progression of primary biliary cirrhosis in Japanese patients.2009
- Author(s)
  稲嶺達夫, 大曲勝久, 塚元和弘, et al.
- Organizer
  59th American Society of Human Genetics Annual Meeting
- Place of Presentation
  Honolulu, USA
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] Haplotype and diplotype polymorphisms of HNF-4α as a genetic biomarker for susceptible to the severe progression of primary biliary cirrhosis in Japanese patients.2009
- Author(s)
  野口扶美枝, 大曲勝久, 塚元和弘, et al.
- Organizer
  59th American Society of Human Genetics Annual Meeting
- Place of Presentation
  Honolulu, USA
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] CYP7A1遺伝子は原発性胆汁性肝硬変の重症化感受性遺伝子である2009
- Author(s)
  比嘉辰伍, 大曲勝久, 塚元和弘, 他
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] The cholesterol 7 alpha-hydroxylase gene susceptible to the severe progression of primary biliary cirrhosis in Japanese patients.2009
- Author(s)
  比嘉辰伍, 大曲勝久, 塚元和弘, et al.
- Organizer
  59th American Society of Human Genetics Annual Meeting
- Place of Presentation
  Honolulu, USA
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] PBC進行とMRP2遺伝子多型との相関解析2009
- Author(s)
  比嘉辰伍, 大曲勝久, 塚元和弘, 他
- Organizer
  第30回日本臨床薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] Polymorphisms of the genes encoding hepatobiliary transporters are associated with susceptibility to the severe progression of primary biliary cirrhosis in Japanese patients.2009
- Author(s)
  稲嶺達夫, 大曲勝久, 塚元和弘, et al.
- Organizer
  第3回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] Identification of serological and genetic biomarkers for predicting the prognosis of primary biliary cirrhosis (PBC) : a homozygous "Hap2/Hap 2" diplotype in multidrug resistance protein 3 (MDR3) gene confers a strong susceptibility to jaundice-type progression of PBC.2008
- Author(s)
  Nakamura M, Omagari K, Tsukamoto K, et al.
- Organizer
  59th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] PBCの重症化関連遺伝子の同定2008
- Author(s)
  飯尾直美, 大曲勝久, 塚元和弘, 他
- Organizer
  第29回日本臨床薬理学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] MDR3はPBCの重症化関連遺伝子である2008
- Author(s)
  大石裕樹, 大曲勝久, 塚元和弘, 他
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] PBCの重症化関連遺伝子の同定2008
- Author(s)
  飯尾直美, 大曲勝久, 塚元和弘, 他
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590545
[Presentation] Identification of serological and genetic biomarkers for predicting the prognosis of primary biliary cirrhosis (PBC). -A homozygous "Hap2/Hap 2" diplotype in multidrug resistance protein 3 (MDR3) gene confers a strong susceptibility to jaundice-type progression of PBC-.2008
- Author(s)
  Nakamura M, Tsukamoto K, Omagari K, et al.
- Organizer
  59th Annual Meeting of the American Association for the study of Liver Diseases 2008
- Place of Presentation
  San Francisco, USA
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-20590545

1. NAKAMURA Sadako (60382438)

# of Collaborated Projects : 2results

# of Collaborated Products : 1results
2. OKU Tsuneyuki (50010096)

# of Collaborated Projects : 2results

# of Collaborated Products : 1results
3. TSUKAMOTO Kazuhiro (30253305)

# of Collaborated Projects : 1results

# of Collaborated Products : 23results
4. INAMINE Tatsuo (00549628)

# of Collaborated Projects : 1results

# of Collaborated Products : 6results
5. 森田茂樹 (00220062)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. 田辺賢一 (60585727)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. 中山敏幸 (30284673)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. OHISHI Yuki

# of Collaborated Projects : 1results

# of Collaborated Products : 3results
9. IIO Naomi

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
10. HIGA Shingo

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
11. NOGUCHI Fumie

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
12. KAWAUCHI Ayumi

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
13. HASHIGUCHI Toshie

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. UDA Sayaka

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. OKABE Yuri

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. SASAKI Mari

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. ICHIMURA Mayuko

# of Collaborated Projects : 1results

# of Collaborated Products : 8results
18. HATANAKA Maiko

# of Collaborated Projects : 1results

# of Collaborated Products : 3results
19. KATO Shigeko

# of Collaborated Projects : 1results

# of Collaborated Products : 5results
20. TSUNEYAMA Koichi

# of Collaborated Projects : 1results

# of Collaborated Products : 9results
21. GOTO Shiho

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
22. SAKAMOTO Ai

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
23. TORII Haruna

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
24. HATTORI Miki

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
25. KAWASE Miku

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
26. MASUZUMI Miki

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
27. SAKAKI Mika

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
28. INOUE Shin-ichi

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
29. TANAKA Yuna

# of Collaborated Projects : 1results

# of Collaborated Products : 5results
30. MURAYAMA Toshie

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
31. YOSHIKAWA Chisato

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
32. SURUGA KAZUHITO

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

OMAGARI Katsuhisa 大曲 勝久

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Correlation among the delaying effect on the onset of diseases and hydrogen produced from intestinal microbes by intake of nondigestible saccharide

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Investigation of pathogenic mechanism of non-alcoholic steatohepatitis and nutritional treatment based on the mechanismPrincipal Investigator

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Effect on the suppression to diarrhea by hydrogen derived from the fermentation of intestinal microbes by the ingestion of nondigestible oligosaccharide.

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Identification of primary biliary cirrhosis-susceptibility genes to the progression and its application to DNA-based diagnosisPrincipal Investigator

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Development and its application of serum marker for the evaluation of staging in primary biliary cirrhosisPrincipal Investigator

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[Book] 臨床薬理の進歩-胆汁酸の排泄に関与するABCトランスポーター多型と原発性胆汁性肝硬変の重症化との関連-2010

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[Journal Article] igh-fat and high-cholesterol diet rapidly induces non-alcoholic steatohepatitis with advanced fibrosis in Sprague-Dawley rats.2015

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[Journal Article] An SHR/NDmcr-cp rat model of non-alcoholic steatohepatitis with advanced fibrosis induced by a high-fat, high-cholesterol diet.2015

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[Journal Article] Abdominal subcutaneous adipose tissue accumulation is positively correlated with hepatic steatosis in Sprague-Dawley rats.2014

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[Journal Article] Phycocyanin prevents hypertension and low serum adiponectin level in a rat model of metabolic syndrome.2013

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[Journal Article] ヒトにおけるダイフルクトースアンハイドライトIIIおよびマンニトールの一過性下痢に対する最大無作用量の評価2012

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[Journal Article] A polymorphism in the integrin αV subunit gene affects the progression of primary biliary cirrhosis in Japanese patients.2011

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[Journal Article] 胆汁酸の排泄に関与するABCトランスポーター多型と原発性胆汁性肝硬変の重症化との関連2010

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[Journal Article] Single-nucleotide polymorphism analysis of the multidrug resistance protein 3 gene for the detection of clinical progression in Japanese patients with primary biliary cirrhosis.2008

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[Journal Article] Single-nucleotide polymorphism analysis of the multidrug resistance protein 3 gene for the detection of clinical progression in Japanese patients with primary biliary cirrhosis.2008

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[Journal Article] Reconsideration of autoimmune cholangitis2005

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OMAGARI Katsuhisa 大曲勝久