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MASAKI Hideyuki  正木 秀幸

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… Alternative Names

正木 秀幸  マサキ ヒデユキ

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Researcher Number 90247982
Other IDs
Affiliation (Current) 2025: 近畿大学, 生物理工学部, 准教授
Affiliation (based on the past Project Information) *help 2018 – 2023: 近畿大学, 生物理工学部, 准教授
2015: 近畿大学, 生物理工学部, 准教授
2007 – 2014: Kinki University, 医学部, 講師
1996 – 1997: 近畿大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 58020:Hygiene and public health-related: including laboratory approach / Hygiene
Except Principal Investigator
Basic Section 54030:Infectious disease medicine-related / Virology
Keywords
Principal Investigator
乳酸菌 / 酵母菌 / ジカウイルス / 感染防護 / 感染防御 / 中和抗体 / cross-presentation / CTL / 組換えワクチン / 成分ワクチン … More / E蛋白質 / ウエストナイルウイルス / コレラトキシンB / 粘膜ワクチン / GFP / エンベロープ蛋白質 / 経口粘膜ワクチン / CTL / 組換え蛋白 / 組換え蛋白質 / E蛋白質 … More
Except Principal Investigator
中和活性 / モノクローナル抗体 / X線結晶構造解析 / 中和抗体 / フラビウイルス / MDシミュレーション / 立体構造解析 / エンベロープタンパク質 / 中和モノクローナル抗体 / ウエストナイルウイルス / Dengue hemorrhagic fever / T lymphocyte / Japanese encephalitis virus / Dengue virus / デンブウイルス / デング出血熱 / T細胞 / 日本脳炎ウイルス / デングウイルス Less
  • Research Projects

    (7 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (11 People)
  •  Optimization for Zika virus oral mucosal vaccine using recombinant saccharomyces and lactobacilliPrincipal Investigator

    • Principal Investigator
      正木 秀幸
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Kindai University
  •  Research and development of monoclonal antibodies that can strictly distinguish Flavi viruses

    • Principal Investigator
      KATO Ryuichi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54030:Infectious disease medicine-related
    • Research Institution
      High Energy Accelerator Research Organization
  •  Basic research for development of oral mucosal vaccine against Zika virus infection using recombinant lactococcus and yeastPrincipal Investigator

    • Principal Investigator
      MASAKI Hideyuki
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Kindai University
  •  Structural basis of neutralized monoclonal antibody which recognizes multiple species of flavivirus

    • Principal Investigator
      Kato Ryuichi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54030:Infectious disease medicine-related
    • Research Institution
      High Energy Accelerator Research Organization
  •  Developement of CTL-inducible West Nile virus vaccine using novel adjuvantPrincipal Investigator

    • Principal Investigator
      MASAKI Hideyuki
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Kinki University
  •  Basic research for development of CTL-inducible vaccine against West Nile virus using recombinant E proteinPrincipal Investigator

    • Principal Investigator
      MASAKI Hideyuki
    • Project Period (FY)
      2007 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Kinki University
  •  Analysis of flavivirus-cross-reactive immune responses which contribute to the pathogenesis of dengue hemorrhagic fever

    • Principal Investigator
      KURANE Ichiro
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      National Institute of Infectious Diseases
      Kinki University

All 2024 2023 2021 2020 2019 2018 2015 2014

All Journal Article Presentation

  • [Journal Article] Human monoclonal antibodies against West Nile virus from Japanese encephalitis-vaccinated volunteers.2018

    • Author(s)
      Ozawa T, Masaki H, Takasaki T, Aoyama I, Yumisashi T, Yamanaka A, Konishi E, Ohnuki Y, Muraguchi A, Kishi H.
    • Journal Title

      Antiviral Res

      Volume: 154 Pages: 58-65

    • DOI

      10.1016/j.antiviral.2018.04.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-16H06499, KAKENHI-PROJECT-15H04980, KAKENHI-PROJECT-18H02689, KAKENHI-PROJECT-18H02855
  • [Presentation] 乳酸菌を用いたジカウイルスに対する経口粘膜ワクチン開発の検討2024

    • Author(s)
      川﨑淳矢、西埜菜津紀、阪上仁頌、正木秀幸、芦田 久
    • Organizer
      2024年度日本農芸化学会大会
    • Data Source
      KAKENHI-PROJECT-21H02971
  • [Presentation] 乳酸菌を用いたジカウイルスに対する経口粘膜ワクチン開発の検討2024

    • Author(s)
      川﨑淳矢、西埜菜津紀、阪上仁頌、正木秀幸、芦田 久
    • Organizer
      2024年度日本農芸化学会大会
    • Data Source
      KAKENHI-PROJECT-22K10495
  • [Presentation] Molecular Dynamics simulation of the complex of the multiple distinctive structurral regions in the WNV envelope and humanmonoclonal antibody2024

    • Author(s)
      Masahito Yoshikawa, Hideyuki Masaki, Ryuuichi Kato, Tatsuhiko Ozawa, Naoyuki Miyashita
    • Organizer
      21st IUPAB Congress 2024 (IUPAB2024)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02971
  • [Presentation] MDシミュレーションを用いたWNVエンベロープ蛋白質部分モデルと中和ヒトモノクロナール抗体との相互作用に関する研究2023

    • Author(s)
      吉川誠仁, 加藤龍一, 小澤龍彦, 正木秀幸, 宮下尚之
    • Organizer
      第29回トガ・フラビ・ペスチウイルス研究会
    • Data Source
      KAKENHI-PROJECT-21H02971
  • [Presentation] 経口粘膜ワクチン開発に向けたジカウイルスエンベロープ蛋白質発現酵母菌株の樹立2021

    • Author(s)
      坂口久峻、辻 彩花、東 慶直、正木秀幸、加藤暢宏
    • Organizer
      第60回日本生体医工学会大会
    • Data Source
      KAKENHI-PROJECT-21H02971
  • [Presentation] Recognition mechanism of a monoclonal antibody which neutralizes different species of flavivirus2021

    • Author(s)
      Kobayashi J, Ozawa T, Masaki H, Kato R
    • Organizer
      第21回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-21H02971
  • [Presentation] 経口粘膜ワクチン開発に向けたジカウイルスエンベロープ蛋白質発現酵母菌株の樹立2021

    • Author(s)
      坂口久峻、辻 彩花、東 慶直、正木秀幸、加藤暢宏
    • Organizer
      第60回日本生体医工学会大会
    • Data Source
      KAKENHI-PROJECT-18K10034
  • [Presentation] 複数のエピトープと結合するモノクローナル抗体の認識機構ークラスター状結晶からの構造解析ー2020

    • Author(s)
      小林淳, 小澤龍彦, 正木秀幸, 加藤龍一
    • Organizer
      日本結晶学会2020年度年会
    • Data Source
      KAKENHI-PROJECT-18H02855
  • [Presentation] Human anti-WNV monoclonal antibodies established from JEV-vaccinated volunteers.2019

    • Author(s)
      Masaki H, Ozawa T, Takasaki T, Aoyama I, Yumisashi T, Yamanaka A, Konishi E, Muraguchi A, Kishi H.
    • Organizer
      ファーマラボEXPOアカデミックフォーラム
    • Data Source
      KAKENHI-PROJECT-18H02855
  • [Presentation] ISAAC法による日本脳炎ワクチン被接種者末梢血単核球からのヒト抗ウエストナイルウイルス中和モノクローナル抗体の樹立2015

    • Author(s)
      正木秀幸、小澤龍彦、高崎智彦、青山幾子、弓指孝博、小西英二、岸 裕幸、村口 篤
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2015-11-22
    • Data Source
      KAKENHI-PROJECT-23590761
  • [Presentation] Establishment of West Nile virus - neutralizing human monoclonal antibodies derived from the individuals vaccinated with inactivated Japanese encephalitis virus by ISAAC technology (2nd.)2015

    • Author(s)
      MASAKI Hideyuki, OZAWA Tatsuhiko, TAKASAKI Tomohiko, KISHI Hiroyuki, MURAGUCHI Atsushi
    • Organizer
      第44回日本免疫学会総会・学術集会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-23590761
  • [Presentation] ISAAC法による日本脳炎ワクチン被接種者末梢血単核球からのヒト抗ウエストナイルウイルス中和モノクローナル抗体の樹立(第2報)2015

    • Author(s)
      正木秀幸、小澤龍彦、高崎智彦、青山幾子、弓指孝博、小西英二、岸 裕幸、村口 篤
    • Organizer
      第22回トガ・フラビ・ペスチウイルス研究会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2015-11-21
    • Data Source
      KAKENHI-PROJECT-23590761
  • [Presentation] ISAAC法による日本脳炎ワクチン被接種者末梢単核球からのヒト抗ウエストナイルウイルス中和モノクローナル抗体の樹立2014

    • Author(s)
      正木秀幸、小澤龍彦、高崎智彦、青山幾子、弓指孝博、小西英二、岸 裕幸、村口 篤
    • Organizer
      第21回 トガ・フラビ・ペスチウイルス研究会
    • Place of Presentation
      横浜市
    • Year and Date
      2014-11-09
    • Data Source
      KAKENHI-PROJECT-23590761
  • [Presentation] Establishment of West Nile virus - neutralizing human monoclonal antibodies derived from the individuals vaccinated with inactivated Japanese encephalitis virus by ISAAC technology.2014

    • Author(s)
      Masaki, H., Ozawa, T., Takasaki, T., Kishi, H., Muraguchi, A
    • Organizer
      第43回 日本免疫学会総会・学術集会
    • Place of Presentation
      京都市
    • Year and Date
      2014-12-11
    • Data Source
      KAKENHI-PROJECT-23590761
  • 1.  TAKASAKI Tomohiko (20221351)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  KURANE Ichiro (90278656)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  Kato Ryuichi (50240833)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 4.  芦田 久 (40379087)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 5.  東 慶直 (90333509)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  小澤 龍彦 (10432105)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 7.  KONISHI Eiji (40135786)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  宮下 尚之 (20452162)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  SATOH Mayumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KUWAHARA Miwa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  岸 裕幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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