MIYAKE Koichi 三宅弘一

… Alternative Names

三宅弘一ミヤケコウイチ

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Researcher Number	90267211
Other IDs
Affiliation (Current)	2025: 日本医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 日本医科大学, 医学部, 教授 2007 – 2019: Nippon Medical School, Faculty of Medicine, Associate Professor 2017: 日本医科大学, 医学部, 講師 2013: 日本医科大学, 医学部, 准教授(Associate Professor) 2000 – 2006: 日本医科大学, 医学部, 講師 2003: 日本医大, 医学部, 講師 1995 – 1998: 日本医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Pediatrics / Hematology / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Pediatrics / Respiratory organ internal medicine / Basic Section 58010:Medical management and medical sociology-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Hematology / Anesthesiology / 膠原病・アレルギー・感染症内科学 … More / Pediatrics / Human genetics / Environmental physiology (including Physical medicine and Nutritional physiology) / General surgery / Biological Sciences Less
Keywords	Principal Investigator 遺伝子治療 / 貧血 / リボゾーム蛋白 / siRNA / 先天性貧血 / 先天異常 / RPS19 / 造血幹細胞 / アデノ随伴ウイルス（AAV）ベクター / 霊長類 … More / 筋肉注射 / アデノ随伴ウイルスベクター / アルカリフォスファターゼ / 低フォスファターゼ症 / Erythropoietin / Signal Transduction / Micro Array / Cell cycle / Ribosomal Protein / Anoutosis / Congenital Anemia / 遺伝子 / エリスリポエチン / シグナル伝達 / マイクロアレー / 細胞周期 / アポトーシス / リボゾームタンパク質 / ダイヤモンド・ブラックファン貧血 / リボゾーム蛋白質 / レンチウイルスベクター / Diamond-Blackfan anemia / リボゾーマル蛋白 / モデル動物 / ウイルスベクター / 多発性骨髄腫 / 血管新生抑制物質 / echotropicレトロウイルスベクター / 組織特異的プロモーター / レトロウイルスベクター / アデノウイルスベクター / リンパ球 / HIVベクター / CD34. / アデノ随伴ウィルス … More Except Principal Investigator 遺伝子治療 / 異染性白質ジストロフィー / リソゾーム病 / 間質性肺炎 / AAV vector / アデノ随伴ウイルス / HIVベクター / ウイルスベクター / 医学教育 / 機械学習 / PBLチュートリアル / マイクロRNA / 血液脳関門 / human immunodeficiency virus / adeno-associated virus / angiostatin / gene therapy / AAVベクター / Gene therapy / アルカリホスファターゼ / 低ホスファターゼ症 / 中枢神経病変 / microRNA / miRNA / 遺伝子 / アデノウイルスベクター / 骨髄幹細胞 / 血管新生抑制因子 / 非分裂細胞 / 膵癌 / 血管新生 / チューター / Problem Based Learning / 作問学修 / チュータースキル / 討論議事録 / PBLチューター / 議事録解析 / 異染性白質ジストロフィ－ / ライソゾーム病 / バイオマーカー開発 / RAS / 疾患マーカー / 骨化 / OP / 骨髄移植関連肺病変 / 瘢痕性器質化肺炎 / 弾性線維新生 / PPFE / COP / UIP / 早期線維化巣 / エクソゾーム / II型肺胞上皮 / エクソソーム / 気管支肺胞洗浄液 / テロメア / 遺伝子変異 / DNAヘリカーゼ遺伝子 / ACD / TEP1 / TEP1遺伝子 / TINF2遺伝子 / ACD遺伝子 / 新規遺伝子変異 / テロメラーゼ活性 / テロメア制御遺伝子異常 / 先天性角化不全症 / 一次感覚神経 / クラスター / 神経障害性疼痛 / ＡＬＰ / ALP / ＡＡＶベクター / 低ホスファターゼ血症 / アデノ随伴ウイルスベクター / 脳神経病変 / Metachromatic leukodystrophy / Mannose-6 phosp[hate receptor / Lysosomal diseases / Blood brain barrier / Viral vector / トランスサイトーシス / マンノース6リン酸 / アリルスルファターゼ / マンノース-6-リン酸受容体 / angiogenic inhibitory factor / collagen-induced arthritis mice / rheumatoid arthritis / コラーゲン関節炎 / 間接リウマチ / コラーゲン関節炎マウス / 関節リウマチ / neural stem cells / stem cells / lysosomal disorders / cell therapy / 多能性骨髄幹細胞 / 脂肪組織由来幹細胞 / 多能性幹細胞 / アリルサルファターゼ / 異染性ロイコジストロフィー / 神経幹細胞 / 幹細胞 / 細胞治療 / Adenovirus vector / Non dividing cells / HIV vector / CD4 / 遺伝子導入 / アデノウイルスベタタ- / 炎症急性期 / 非腫瘍性肺疾患 / 再生 / サバイビン / アルカリフォスファターゼ / 低フォスファターゼ症 / レンチウイルスベクター / 骨格筋芽細胞 / 造血幹細胞 / 再生・細胞医療 / マイクロダイセクション / 水素治療 / D1CC / リウマチ / Castleman's disease / IgG4 / 高濃度水素分子 / RA肺モデル / リンパ球増殖性肺疾患 / 抗酸化作用 / Sp-D / 高濃度水素水 / D1CCマウス / RA肺モデル / Castleman’s disease / IgG4関連肺病変 / リンパ球増殖性肺疾患 / 新生児治療 / 血管新生抑制薬 / multivesicular body / exosome / 肺胞上皮 / 細胞移動 / 細胞新生 / 性ホルモン / 性差 / EGFP / 性分化 / エストロゲン / 性的二型核 / AVPV / male rat / sexual behavior / siRNA / 性的二系核 / ソマトスタチン / calbindin / SDN-POA / MDA7/IL24 / gemcitabine / MDA7/IL-24 / 遺伝病 / レトロウイルスベクター / 脳神経細胞 / 骨髄移植 / HoxB4 / 先天異常学 / 遺伝 / ATL / エイズ / 白血病 / アンギオスタチン / エンドスタチン / 血管新生阻害 / 多発性骨髄腫 / リンパ腫 / 挿入変異 Less

AI advice for effective PBL assignment creation -Development of assignment writing support tools-
- Principal Investigator
  
  早坂明哲
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Nippon Medical School
Development of gene therapy for hypophosphatasiaPrincipal Investigator
- Principal Investigator
  
  三宅弘一
- Project Period (FY)
  2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nippon Medical School
機械学習で議事録を分析：PBLチュートリアルチューター支援システムの開発
- Principal Investigator
  
  早坂明哲
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Nippon Medical School
Development of a novel therapy (gene therapy) for metachromatic leukodystrophy
- Principal Investigator
  
  Miyake Noriko
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Nippon Medical School
Biomarker development and clinical application by extraction of pathogenesis-related factors from early fibrosis foci of interstitial pneumonia
- Principal Investigator
  
  Terasaki Yasuhiro
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
The identification of the novel gene mutation and development of the novel therapy for dyskeratosis congenita
- Principal Investigator
  
  Yamaguchi Hiroki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nippon Medical School
Development a novel gene therapy for Lysosomal disease with neurological disorders
- Principal Investigator
  
  MIYAKE NORIKO
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
The gene therapy for hypophosphatasia animal model
- Principal Investigator
  
  Matsumoto Tae
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
Elucidation of molecular mechanism of survivin in inflammatory lung disease and development of new gene therapy method
- Principal Investigator
  
  Terasaki Mika
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Development of mouse model and therapy of Diamond-Blackfan anemiaPrincipal Investigator
- Principal Investigator
  
  Miyake Koichi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
MicroRNA and exosome in interstitial pneumonia
- Principal Investigator
  
  Kunugi Shinobu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Analysis of lymphoplasmacyte infiltrating fibrotic lung lesion using samples from human lung diseases and RA lung model in D1CC mice
- Principal Investigator
  
  terasaki yasuhiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Development of regenerative medicine and cell therapy for inherited metabolic diseases using hypophosphatasia mice
- Principal Investigator
  
  Iijima Osamu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
Comprehensive analysis of neuropathic pain-specific microRNA cluster
- Principal Investigator
  
  Sakai Atsushi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Nippon Medical School
Development of novel gene therapy for CNS disorders of lysosomal diseases
- Principal Investigator
  
  MIYAKE NORIKO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
Physiological function of the rat SDN-POA analyzed by sst-siRNA recombinant adenovirus vector
- Principal Investigator
  
  ORIKASA Chitose
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Nippon Medical School
Analysis of angiogenetic factor in interstitial pneumonia
- Principal Investigator
  
  KUNUGI Shinobu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Development of molecular mechanism and therapy of Diamond-Blackfan anemiaPrincipal Investigator
- Principal Investigator
  
  KOICHI Miyake
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
Perinatal gene therapy for severe genetic diseases
- Principal Investigator
  
  SHIMADA Takashi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
The novel gene therapy using adeno-associated viral vector mediatedMDA7/IL-24 for human pancreatic cancer
- Principal Investigator
  
  AIMOTO Takayuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Nippon Medical School
Development of novel bone marrow transplantation for treatment of CNS disorders in lysosomal disease.
- Principal Investigator
  
  MIYAKE Noriko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
Development of mouse model and novel gene therapy for Diamond-Blackfan anemiaPrincipal Investigator
- Principal Investigator
  
  MIYAKE Koichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
Molecular mechanism and development of gene therapy for Diamond-Blackfan anemiaPrincipal Investigator
- Principal Investigator
  
  MIYAKE Koichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
Non-invasive gene therapy for inherited neurodegenerative disorders (How to cross the BBB?)
- Principal Investigator
  
  SHIMADA Takashi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
Gene therapy for rheumatoid arthritis using transduction with angiogenesis inhibitory factor
- Principal Investigator
  
  NAGASHIMA Masakazu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Nippon Medical School
血管新生抑制物質による多発性骨髄腫の新規治療法(遺伝子治療)の開発Principal Investigator
- Principal Investigator
  
  三宅弘一
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nippon Medical School
Therapeutic strategies for inherited neurodegerative disorders using gene transfer and stem-cell transplantation technologies
- Principal Investigator
  
  SHIMADA Takashi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
HIVベクターの開発
- Principal Investigator
  
  SHIMADA Takashi
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nippon Medical School
遺伝子治療を目的とた安全でかつ高率な組織特異的遺伝子導入法の開発Principal Investigator
- Principal Investigator
  
  三宅弘一
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Nippon Medical School
HIVベクターによる血球系細胞(リンパ球、造血幹細胞)への遺伝子導入Principal Investigator
- Principal Investigator
  
  三宅弘一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Nippon Medical School
アデノ随伴ウィルスベクターによる造血幹細胞への遺伝子導入Principal Investigator
- Principal Investigator
  
  三宅弘一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Nippon Medical School
GENE TRANSFER INTO NON DIVIDING CELLS BY MEANS OF HIV
- Principal Investigator
  
  SHIMADA Takashi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  NIPPON MEDICAL SCHOOL

[Book] Neonatal Gene Therapy for Inherited Disorders. Selected Topics in Neonatal Care.2018
- Author(s)
  Miyake K, Miyake N, Shimada T.
- Total Pages
  9
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-15K09604
[Book] Neonatal Gene Therapy for Inherited Disorders. Selected Topics in Neonatal Care.2018
- Author(s)
  Miyake K, Miyake N, Shimada T.
- Total Pages
  9
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-15K09605
[Book] Neonatal Gene Therapy for Inherited Disorders. Selected Topics in Neonatal Care.2018
- Author(s)
  Miyake K, Miyake N, Shimada T.
- Total Pages
  9
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-18K07859
[Book] Gene Therapy - Principles and Challenges2015
- Author(s)
  Koichi Miyake, Noriko Miyake and Takashi Shimada
- Total Pages
  208
- Publisher
  INTECh
- Data Source
  KAKENHI-PROJECT-26461596
[Book] Gene Therapy - Principles and Challenges2015
- Author(s)
  Koichi Miyake, Noriko Miyake and Takashi Shimada
- Total Pages
  208
- Publisher
  INTEC
- Data Source
  KAKENHI-PROJECT-15K09604
[Book] Novel Gene Therapy Approaches2013
- Author(s)
  Miyake K, Shimada T
- Total Pages
  450
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-23591554
[Book] Development of Muscle-Directed Systemic Cancer Gene Therapy. Novel Gene Therapy Approaches2013
- Author(s)
  Miyake K, Shimada T
- Publisher
  Edited by Ming Wei and David Good, Published by InTech
- Data Source
  KAKENHI-PROJECT-23591554
[Book] Development of muscle directed systemic cancer gene therapy.2013
- Author(s)
  Miyake, K., Shimada, T.
- Publisher
  GeneTherapy/Book 1 (Edited by MingWei) InTech.
- Data Source
  KAKENHI-PROJECT-22390212
[Book] Novel gene therapy approaches2013
- Author(s)
  Miyake K, Shimada T.
- Total Pages
  440
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-24591529
[Book] Novel Gene Therapy Approaches2013
- Author(s)
  Miyake K,Shimada T
- Total Pages
  396
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-22591444
[Book] Development and Application of HIV Vectors Pseudotyped with HIV Envelopes. Viral Gene Therapy2011
- Author(s)
  Miyake K, Shimada T
- Publisher
  Edited by Ke Xu, Published by InTech
- Data Source
  KAKENHI-PROJECT-23591554
[Book] Development and application of HIVvectors pseudotyped with HIV envelopes.2011
- Author(s)
  Miyake, K., Shimada, T.
- Publisher
  Viral Gene Therapy (Edited by Ke Xu)
- Data Source
  KAKENHI-PROJECT-22390212
[Book] Viral gene therapy2011
- Author(s)
  Koichi Miyake, Takashi Shimada
- Total Pages
  16
- Publisher
  Intec
- Data Source
  KAKENHI-PROJECT-23591554
[Book] 医歯2011
- Author(s)
  三宅紀子
- Publisher
  薬出版株式会社
- Data Source
  KAKENHI-PROJECT-20591234
[Book] InTech, Viral Gene Therapy2011
- Author(s)
  Miyake K
- Total Pages
  450
- Publisher
  Shimada T
- Data Source
  KAKENHI-PROJECT-22591444
[Book] 医学のあゆみ2011
- Author(s)
  三宅紀子, 他
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-20591234
[Journal Article] 2.Treatment of adult metachromatic leukodystrophy model mice using intrathecal administration of type 9 AAV vector encoding arylsulfatase A.2021
- Author(s)
  Miyake N, Miyake K, Sakai A, Yamamoto M, Suzuki H, Shimada T.
- Journal Title
  
  Sci Rep.
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-99979-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07859, KAKENHI-PROJECT-21K07781
[Journal Article] A new method for in vivo targeted gene transfer into oligodendrocytes using adenoviral and HIV vectors.2021
- Author(s)
  1.Miyake K, Miyake N and Shimada T.
- Journal Title
  
  Biomedical J. of Sci. & Tec. Res.
  
  Volume: 3 Issue: 3 Pages: 31379-31385
- DOI
  10.26717/bjstr.2021.39.006306
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07859
[Journal Article] Malignant pleural mesothelioma with heterologous elements2021
- Author(s)
  Kawai Toshiaki、Seki Reishi、Miyajima Kuniharu、Nakashima Hiroshi、Takeda Takayuki、Murakami Tomoyuki、Aoe Keisuke、Okabe Kazunori、Homma Keiichi、Tsukamoto Yoshitane、Sunada Koichi、Terasaki Yasuhiro、Iida Maki、Orikasa Hideki、Hiroshima Kenzo
- Journal Title
  
  Journal of Clinical Pathology
  
  Volume: - Issue: 10 Pages: 690-695
- DOI
  10.1136/jclinpath-2021-207575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09630, KAKENHI-PROJECT-20K08553
[Journal Article] 1.Treatment with bone maturation and average lifespan of HPP model mice by AAV8-mediated neonatal gene therapy via single muscle injection.2021
- Author(s)
  Matsumoto T, Miyake K, Miyake N, Iijima O, Adachi K, Narisawa S, Millan JL, Orimo H, Shimada T.
- Journal Title
  
  Mol Ther Methods Clin Dev.
  
  Volume: 22 Pages: 330-337
- DOI
  10.1016/j.omtm.2021.06.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07859
[Journal Article] 1.TERT and TERC mutations detected in cryptic dyskeratosis congenita suppress telomerase activity.2020
- Author(s)
  Terada K, Miyake K, Yamaguchi H, Miyake N, Yamanaka K, Kojima S, Ito E, Inokuchi K, Okada T.
- Journal Title
  
  Int J Lab Hematol.
  
  Volume: - Issue: 3 Pages: 316-321
- DOI
  10.1111/ijlh.13176
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07859
[Journal Article] 2.Tbx6 induces cardiomyocyte proliferation in postnatal and adult mouse hearts.2019
- Author(s)
  Haginiwa S, Sadahiro T, Kojima H, Isomi M, Tamura F, Kurotsu S, Tani H, Muraoka N, Miyake N, Miyake K, Fukuda K, Ieda M.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 513 Issue: 4 Pages: 1041-1047
- DOI
  10.1016/j.bbrc.2019.04.087
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07859, KAKENHI-PROJECT-18K08114, KAKENHI-PROJECT-19K22613, KAKENHI-PROJECT-18J21479, KAKENHI-PROJECT-17K19678, KAKENHI-PROJECT-18K15861, KAKENHI-PROJECT-17H04179
[Journal Article] MicroRNA cluster miR-17-92 regulates multiple functionally related voltage-gated potassium channels in chronic neuropathic pain2017
- Author(s)
  Sakai Atsushi、Saitow Fumihito、Maruyama Motoyo、Miyake Noriko、Miyake Koichi、Shimada Takashi、Okada Takashi、Suzuki Hidenori
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 16079-16079
- DOI
  10.1038/ncomms16079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09604, KAKENHI-PROJECT-16K10986, KAKENHI-PROJECT-16K15340, KAKENHI-PROJECT-17K16758, KAKENHI-PROJECT-26293328, KAKENHI-PROJECT-16H05461, KAKENHI-PROJECT-26461596
[Journal Article] Improved Intravitreal AAV-Mediated Inner Retinal Gene Transduction after Surgical Internal Limiting Membrane Peeling in Cynomolgus Monkeys.2017
- Author(s)
  Takahashi K, Igarashi T, Miyake K, Kobayashi M, Yaguchi C, Iijima O, Yamazaki Y, Katakai Y, Miyake N, Kameya S, Shimada T, Takahashi H, Okada T.
- Journal Title
  
  Mol Ther.
  
  Volume: 4；25 Issue: 1 Pages: 296-302
- DOI
  10.1016/j.ymthe.2016.10.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293328, KAKENHI-PROJECT-15K09604, KAKENHI-PROJECT-26461596
[Journal Article] miR-15b mediates oxaliplatin-induced chronic neuropathic pain through BACE1 down-regulation.2017
- Author(s)
  Ito N, Sakai A, Miyake N, Maruyama M, Iwasaki H, Miyake K, Okada T, Sakamoto A, Suzuki H.
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 174 Issue: 5 Pages: 386-395
- DOI
  10.1111/bph.13698
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05461, KAKENHI-PROJECT-26861253, KAKENHI-PROJECT-16K10986, KAKENHI-PROJECT-16K15340, KAKENHI-PROJECT-15K10525, KAKENHI-PROJECT-26461596
[Journal Article] Amlexanox Downregulates S100A6 to Sensitize KMT2A/AFF1-Positive Acute Lymphoblastic Leukemia to TNFα Treatment2017
- Author(s)
  Hayato Tamai, Hiroki Yamaguchi, Koichi Miyake, Miyuki Takatori, Tomoaki Kitano, Satoshi Yamanaka, Syunsuke Yui, Keiko Fukunaga, Kazutaka Nakayama and Koiti Inokuchi
- Journal Title
  
  Cancer Research
  
  Volume: 77 Issue: 16 Pages: 4426-4433
- DOI
  10.1158/0008-5472.can-16-2974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461596
[Journal Article] D816V mutation in the KIT gene activation loop has greater cell-proliferative and anti-apoptotic ability than N822K mutation in core-binding factor acute myeloid leukemia2017
- Author(s)
  Omori Ikuko、Yamaguchi Hiroki、Miyake Koichi、Miyake Noriko、Kitano Tomoaki、Inokuchi Koiti
- Journal Title
  
  Experimental Hematology
  
  Volume: 52 Pages: 56-64.e4
- DOI
  10.1016/j.exphem.2017.05.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09604, KAKENHI-PROJECT-17K09942, KAKENHI-PROJECT-26461596
[Journal Article] Tyrosine triple mutated AAV2-BDNF gene therapy in a rat model of transient IOP elevation2016
- Author(s)
  Igarashi T, Miyake K, Kobayashi M, Kameya S, Fujimoto C, Nakamoto K, Takahashi H, Igarashi T, Miyake N, Iijima O, Hirai Y, Shimada T, Okada T, Takahashi H.
- Journal Title
  
  Mol Vis.
  
  Volume: 16 Pages: 816-826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09604
[Journal Article] Treatment of hypophosphatasia by muscle-directed expression of bone-targeted alkaline phosphatase via self-complementary AAV8 vector.2016
- Author(s)
  Nakamura-Takahashi,A., Miyake,K., Watanabe, A., Hirai, Y., Iijima, O., Miyake, N., Adachi K.,, Nitahara-Kasahara, Y., Kinoshita, H., Noguchi, T., Abe, S., Narisawa, S., Millán, J. L., Shimada, T.,Okada, T.
- Journal Title
  
  Molecular Therapy- Methods & Clinical Development
  
  Volume: 3 Pages: 15059-15059
- DOI
  10.1038/mtm.2015.59
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460407, KAKENHI-PROJECT-25461564, KAKENHI-PROJECT-26293328
[Journal Article] Tyrosine triple mutated AAV2-BDNF gene therapy in a rat model of transient IOP elevation2016
- Author(s)
  Igarashi T, Miyake K, Kobayashi M, Kameya S, Fujimoto C, Nakamoto K, Takahashi H, Igarashi T, Miyake N, Iijima O, Hirai Y, Shimada T, Okada T, Takahashi H.
- Journal Title
  
  Mol Vis.
  
  Volume: 16 Pages: 816-826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461596
[Journal Article] Uterine leiomyosarcoma with osteoclast-like giant cells associated with high expression of receptor activator for nuclear factor κB ligand ( ANKL)2015
- Author(s)
  Mika Terasaki, M.D., Ph.D; Yasuhiro Terasaki, MD, PhD; Koichi Yoneyama, MD, PhD;
- Journal Title
  
  Human Pathology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461175
[Journal Article] Enzyme replacement in the CSF to treat metachromatic leukodystrophy in mouse model using single intracerebroventricular injection of self-complementary AAV1 vector.2015
- Author(s)
  Hironaka K, Yamazaki Y, Hirai Y, Yamamoto M, Miyake N, Miyake K, Okada T, Morita A, Shimada T.
- Journal Title
  
  Sci Rep.
  
  Volume: 18 Issue: 1 Pages: 1-12
- DOI
  10.1038/srep13104
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09604, KAKENHI-PROJECT-26461596, KAKENHI-PROJECT-25460407, KAKENHI-PROJECT-26293328
[Journal Article] Prevention of Lethal Murine Hypophosphatasia by Neonatal Ex Vivo Gene Therapy Using Lentivirally Transduced Bone Marrow Cells.2015
- Author(s)
  Iijima O, Miyake K, Watanabe A, Miyake N, Igarashi T, Kanokoda C, Nakamura-Takahashi A, Kinoshita H, Noguchi T, Abe S, Narisawa S, Millán JL, Okada T, Shimada T.
- Journal Title
  
  Hum Gene Ther.
  
  Volume: 26 Issue: 12 Pages: 801-12
- DOI
  10.1089/hum.2015.078
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09604, KAKENHI-PROJECT-26461596, KAKENHI-PROJECT-25461564
[Journal Article] Mutant ataxin-3 with an abnormally expanded polyglutamine chain disrupts dendritic development and metabotropic glutamate receptor signaling in mouse cerebellar purkinje cells2014
- Author(s)
  Konno A, Shuvaev AN, Miyake N, Miyake K, Iizuka A, Matsuura S, Huda F, Nakamura K, Yanagi S, Shimada T, Hirai H.
- Journal Title
  
  Cerebellum
  
  Volume: 13 Issue: 1 Pages: 29-41
- DOI
  10.1007/s12311-013-0516-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554, KAKENHI-PUBLICLY-24111545, KAKENHI-PROJECT-24590407, KAKENHI-PROJECT-24591529, KAKENHI-PROJECT-24700394, KAKENHI-PROJECT-24800008, KAKENHI-PROJECT-25640040
[Journal Article] miR-7a alleviates the maintenance of neuropathic pain through regulation of neuronal excitability2014
- Author(s)
  Sakai A, Saitow F, Miyake N, Miyake K, Shimada T, Suzuki H
- Journal Title
  
  Brain
  
  Volume: 136 Pages: 2738-2750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Adeno-associated virus type 8 vector-mediated expression of siRNA targeting vascular endothelial growth factor efficiently inhibits neovascularization in a murine choroidal neovascularization model.2014
- Author(s)
  Igarashi T, Miyake N, Fujimoto C, Yaguchi C, Iijima O, Shimada T, Takahashi H, Miyake K.
- Journal Title
  
  Mol Vis.
  
  Volume: 20 Pages: 488-96
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461596
[Journal Article] Cyclical mechanical stretch enhances degranulation and IL-4 secretion in RBL-2H3 mast cells2014
- Author(s)
  Komiyama H, Miyake K, Asai K, Mizuno K, Shimada T.
- Journal Title
  
  Cell Biochem Funct.
  
  Volume: 32 Issue: 1 Pages: 70-76
- DOI
  10.1002/cbf.2973
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554, KAKENHI-PROJECT-24591529
[Journal Article] siRNA Knockdown of Tissue Inhibitor of Metalloproteinase-1 in Keloid Fibroblasts Leads to Degradation of Collagen Type I2014
- Author(s)
  Aoki M, Miyake K, Ogawa R, Dohi T, Akaishi S, Hyakusoku H, Shimada T.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: 134 Issue: 3 Pages: 818-826
- DOI
  10.1038/jid.2013.396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554, KAKENHI-PROJECT-24591529
[Journal Article] siRNA Knockdown of Tissue Inhibitor of Metalloproteinase-1 in Keloid Fibroblasts Leads to Degradation of Collagen Type I2014
- Author(s)
  Aoki M, Miyake K, Ogawa R, Dohi T, Akaishi S, Hyakusoku H, Shimada T
- Journal Title
  
  J Invest Dermatol
  
  Volume: 134 Pages: 818-826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Cyclical mechanical stretch enhances degranulation and IL-4 secretion in RBL-2H3 mast cells2014
- Author(s)
  komiyama H, Miyake K, Asai K, Mizuno K, Shimada T
- Journal Title
  
  Cell Biochemistry & Function
  
  Volume: 32 Pages: 70-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Targeted gene transfer into ependymal cells through intraventricular injection of AAV1 vector and long-term enzyme replacement via the CSF.2014
- Author(s)
  Yamazaki Y, Hirai Y, Miyake K, Shimada T.
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 5506-5506
- DOI
  10.1038/srep05506
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460407, KAKENHI-PROJECT-26461596
[Journal Article] Long-term correction of biochemical and neurological abnormalities in MLD mice model by neonatal systemic injection of an AAV serotype 9 vector.2014
- Author(s)
  Miyake N, Miyake K, Asakawa N, Yamamoto M, Shimada T.
- Journal Title
  
  Gene Ther.
  
  Volume: 印刷中 Issue: 4 Pages: 427-433
- DOI
  10.1038/gt.2014.17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591529, KAKENHI-PROJECT-26461596
[Journal Article] nhibition of S100A6 induces graft versus leukemia effects in MLL/AF4-positive ALL in human PBMC-SCID mice.2014
- Author(s)
  Tamai.H, Miyake K, Yamaguchi H, Shimada T, Dan K, Inokuchi K.
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 49(5) Issue: 5 Pages: 699-703
- DOI
  10.1038/bmt.2014.18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591412, KAKENHI-PROJECT-24591529, KAKENHI-PROJECT-26461434, KAKENHI-PROJECT-26461596
[Journal Article] Mutant Ataxin-3 with an Abnormally Expanded Polyglutamine Chain Disrupts Dendritic Development and Metabotropic Glutamate Receptor Signaling in Mouse Cerebellar Purkinje Cells2014
- Author(s)
  Konno A, Shuvaev AN, Miyake N, Miyake K, Iizuka A, Matsuura S, Huda F, Nakamura K, Yanagi S, Shimada T, Hirai H
- Journal Title
  
  Cerebellum
  
  Volume: 13 Pages: 29-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] DirectComparison of Administration Routes for AAV8-mediated Ocular Gene Therapy.2013
- Author(s)
  Igarashi T, Miyake K, Asakawa N, MiyakeN, Shimada T, Takahashi H
- Journal Title
  
  Curr Eye Res
  
  Volume: in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] Direct comparison of administration routes for AAV8-mediated ocular gene therapy2013
- Author(s)
  Igarashi T, Miyake K, Asakawa N, Miyake N, Shimada T, Takahashi H.
- Journal Title
  
  Curr Eye Res.
  
  Volume: 38 Issue: 5 Pages: 569-577
- DOI
  10.3109/02713683.2013.779720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554, KAKENHI-PROJECT-24591529
[Journal Article] Direct Comparison of Administration Routes for AAV8-mediated Ocular Gene Therapy2013
- Author(s)
  Igarashi T, Miyake K, Asakawa N, Miyake N, Shimada T, Takahashi H.
- Journal Title
  
  Curr Eye Res
  
  Volume: 38 Pages: 569-577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Team-based Learning Using an Audience Response System : A Possible New Strategy for Interactive Medical Education2013
- Author(s)
  Fujikura T, Takeshita T, Homma H, Adachi K, Miyake K, Kudo M, Takizawa T, Nagayama H, Hirakawa K
- Journal Title
  
  J Nippon Med Sch
  
  Volume: 80 Pages: 63-69
- NAID
  130004147207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Cyclical mechanical stretch enhances degranulation and IL-4 secretion in RBL-2H3 mast cells.2013
- Author(s)
  Komiyama H, Miyake K, Asai K, Mizuno K, Shimada T
- Journal Title
  
  Cell Biochemistry& Function
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] miR-7a alleviates the maintenance of neuropathic pain through regulation of neuronal excitability2013
- Author(s)
  Sakai A, Saitow F, Miyake N, Miyake K, Shimada T, Suzuki H.
- Journal Title
  
  Brain
  
  Volume: 136 Issue: 9 Pages: 2738-2750
- DOI
  10.1093/brain/awt191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554, KAKENHI-PROJECT-24591529, KAKENHI-PROJECT-25460345
[Journal Article] Role of survivin in acute lung injury : epithelial cells of mice and humans2013
- Author(s)
  Terasaki Y, Terasaki M, Urushiyama H, Nagasaka S, Takahashi M, Kunugi S, Ishikawa A, Wakamatsu K, Kuwahara N, Miyake K, Fukuda Y.
- Journal Title
  
  Lab Invest
  
  Volume: 93(10) Pages: 1147-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591164
[Journal Article] Direct Comparison of Administration Routes for AAV8-Mediated Ocular Gene Therapy.2013
- Author(s)
  Igarashi, T., Miyake, K., Asakawa, N., Miyake, N., Shimada, T., Takahashi, H.
- Journal Title
  
  Current Eye Res.
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22390212
[Journal Article] Induction of Cardiomyocyte-like Cells in Infarct Hearts by Gene Transfer of Gata4, Mef2c, and Tbx52012
- Author(s)
  Inagawa K, Miyamoto K, Yamakawa H, Muraoka N, Sadahiro T, Umei T, Wada R, Katsumata Y, Kaneda R, Nakade K, Kurihara C, Obata Y, Miyake K, Fukuda K, Ieda M
- Journal Title
  
  Circulation research
  
  Volume: 111 Issue: 9 Pages: 1147-56
- DOI
  10.1161/circresaha.112.271148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390216, KAKENHI-PROJECT-23501277, KAKENHI-PROJECT-23591554, KAKENHI-PROJECT-23659426
[Journal Article] Serotype-independent Method of Recombinant Adeno-associated. Virus (AAV) Vector Production and Purification2012
- Author(s)
  Miyake K, Miyake N, Yamazaki Y, Shimada T, Hirai Y
- Journal Title
  
  J Nippon Med Sch
  
  Volume: 79 Pages: 394-402
- NAID
  130004057397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Successful gene therapy in utero for lethal murine hypophosphatasia2012
- Author(s)
  Sugano H, Matsumoto T, Miyake K, Watanabe A, Iijima O, Migita M, Narisawa S, Millán JL, Fukunaga Y, Shimada T.
- Journal Title
  
  Hum Gene Ther
  
  Volume: 23 Pages: 399-406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Serotype-independent Method of Recombinant Adeno-associated Virus (AAV) Vector Production and Purification.2012
- Author(s)
  Miyake K, Miyake N, Yamazaki Y, Shimada T, Hirai Y
- Journal Title
  
  J Nippon Med Sch
  
  Volume: 79 Pages: 394-402
- NAID
  130004057397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] AAV-8 vector expressing IL-24 efficiently suppresses tumor growth mediated by specific mechanisms in MLL/AF4-positive ALL model mice2012
- Author(s)
  Tamai H, Miyake K, Yamaguchi H Takatori M, Dan K, Inokuchi K, Shimada T.
- Journal Title
  
  Blood
  
  Volume: 119 Pages: 64-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Successful gene therapy in utero for lethal murine hypophosphatasia.2012
- Author(s)
  Sugano, H., Matsumoto, T., Miyake, K., Watanabe, A., Iijima, O., Migita, M., Narisawa, S., Millan, J.L., Fukunaga, Y., Shimada, T.
- Journal Title
  
  Hum. Gene Ther.
  
  Volume: 23 Pages: 399-406
- Data Source
  KAKENHI-PROJECT-22390212
[Journal Article] Induction of cardiomyocyte-like cells in infarct hearts by gene transfer of gata4, mef2c, and tbx52012
- Author(s)
  Inagawa K, Miyamoto K, Yamakawa H, Muraoka N, Sadahiro T, Umei T, Wada R, Katsumata Y, Kaneda R, Nakade K, Kurihara C, Obata Y, Miyake K, Fukuda K, Ieda M.
- Journal Title
  
  Circ Res
  
  Volume: 111 Pages: 1147-1156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] AAV-8 vector expressing IL-24 efficiently suppresses tumor growth mediated by specific mechanisms in MLL/AF4-positive ALL model mice.2012
- Author(s)
  Tamai, H.
- Journal Title
  
  Blood
  
  Volume: 119 Issue: 1 Pages: 64-71
- DOI
  10.1182/blood-2011-05-354050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390212, KAKENHI-PROJECT-22591051, KAKENHI-PROJECT-23591554
[Journal Article] Induction of cardiomyocyte-like cells in infarct hearts by gene transfer of Gata4, Mef2c, and Tbx5.2012
- Author(s)
  Inagawa K, Miyake K, Fukuda K
- Journal Title
  
  Cir Res
  
  Volume: 111 Pages: 1147-1156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] Serotype-independent method of recombinant adeno-associated virus (AAV) vector production and purification.2012
- Author(s)
  Miyake K, Miyake N, Yamazaki Y, Shimada T, Hirai Y.
- Journal Title
  
  J Nippon Med Sch.
  
  Volume: 79 Pages: 394-402
- NAID
  130004057397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591529
[Journal Article] AAV8 vector expressing IL24 efficiently suppresses tumor growth mediated by specific mechanisms in MLL/AF4-positive ALL model mice.2012
- Author(s)
  Tamai H, Miyake K, Yamaguchi H, Takatori M, Dan K, Inokuchi K, Shimada T
- Journal Title
  
  Blood
  
  Volume: 119 Pages: 64-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] AAV-8 vector expressing IL-24 efficiently suppresses tumor growth mediated by specific mechanisms inMLL/AF4-positive ALL model mice.2012
- Author(s)
  Tamai, H., Miyake, K., Yamaguchi, H., Takatori, M., Dan, K., Inokuchi, K., Shimada, T.
- Journal Title
  
  Blood
  
  Volume: 119 Pages: 64-71
- Data Source
  KAKENHI-PROJECT-22390212
[Journal Article] Successful gene therapy in utero for lethal murine hypophosphatasia.2012
- Author(s)
  Sugano H, Matsumoto T, Miyake K
- Journal Title
  
  Hum Gene Ther.
  
  Volume: 23 Pages: 399-406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] Serotype-independent method of recombinant adeno-associated virus (AAV) vector production and purification.2012
- Author(s)
  Miyake, K., Miyake, N., Yamazaki, Y., Shimada, T., Hirai, Y.
- Journal Title
  
  J Nippon Med Sch.
  
  Volume: 79 Pages: 394-402
- NAID
  130004057397
- Data Source
  KAKENHI-PROJECT-22390212
[Journal Article] Serotype-independent method of recombinant adeno-associated virus (AAV) vector production and purification2012
- Author(s)
  Miyake K, Miyake N, Yamazaki Y, Shimada T, Hirai Y.
- Journal Title
  
  J Nippon Med Sch
  
  Volume: 79 Pages: 394-402
- NAID
  130004057397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Direct comparison of four adeno-associated virus serotypes in mediating the production of antiangiogenic proteins in mouse muscle2011
- Author(s)
  Isotani M, Miyake K, Miyake N, Hirai Y, Shimada T.
- Journal Title
  
  Cancer Invest
  
  Volume: 29(5) Pages: 353-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Direct Comparison of Four Adeno-Associated Virus Serotypes in Mediating the Production of Antiangiogenic Proteins in Mouse Muscle2011
- Author(s)
  Mayu Isotani, Koichi Miyake, Noriko Miyake, Yukihiko Hirai, Takashi Shimada
- Journal Title
  
  Cancer Investigation
  
  Volume: 29 Issue: 5 Pages: 353-359
- DOI
  10.3109/07357907.2011.584585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Direct comparison of four adeno-associated virus serotypes in mediating the production of antiangiogenic proteins in mouse muscle.2011
- Author(s)
  Isotani M, Miyake K, Miyake N, Hirai Y, Shimada T
- Journal Title
  
  Cancer Invest
  
  Volume: 29 Pages: 353-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] Global gene transfer into the CNS across the BBB after neonatal systemic delivery of single-stranded AAV vectors.2011
- Author(s)
  Miyake N, Miyake K, Yamamoto M, Hirai Y, Shimada T
- Journal Title
  
  Brain Res. 1389
  
  Pages: 19-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591234
[Journal Article] Global gene transfer into the CNS across the BBB after neonatal systemic delivery of single-stranded AAV vectors.2011
- Author(s)
  Miyake N, Miyake K, Yamamoto M, Hirai Y, Shimada T
- Journal Title
  
  Brain Res. 10
  
  Pages: 19-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591265
[Journal Article] Global gene transfer into the CNS across the BBB after neonatal systemic delivery of single-stranded AAV vectors.2011
- Author(s)
  Miyake N, Miyake K, Yamamoto M, Hirai Y, Shimada T
- Journal Title
  
  Brain Res
  
  Volume: 10 Pages: 19-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] Direct comparison of four adeno-associated virus serotypes in mediating the production of anti-angiogenic proteins in mouse muscle.2011
- Author(s)
  Isotani, M., Miyake, K., Miyake, N., Hirai, Y., Shimada, T.
- Journal Title
  
  Cancer Invest.
  
  Volume: 29 Pages: 353-359
- Data Source
  KAKENHI-PROJECT-22390212
[Journal Article] Global gene transfer into the CNS across the BBB after neonatal systemic delivery of single-stranded AAV vectors.2011
- Author(s)
  Miyake, N.
- Journal Title
  
  Brain Res.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390212
[Journal Article] Rescue of Severe Infantile Hypophosphatasia Mice by AAV Mediated Sustained Expression of Soluble Alkaline Phosphatase.2011
- Author(s)
  Matsumoto, T., Miyake, K., Yamamoto, S., Orimo, H., Miyake, N., Odagaki, Y.,Adachi, K., Iijima, O., Narisawa, S., Millan, J.L., Fukunaga, Y., Shimada, T.
- Journal Title
  
  Hum. Gene Ther.
  
  Volume: 22 Pages: 1355-1364
- Data Source
  KAKENHI-PROJECT-22390212
[Journal Article] Resistance of MLL-AFF1-positive acute lymphoblastic leukemia to tumor necrosis factor-alpha is mediated by S100A6 up-regulation2011
- Author(s)
  Tamai H, Miyake K, Yamaguchi H Takatori M, Dan K, Inokuchi K, Shimada T.
- Journal Title
  
  Blood Cancer Journal
  
  Volume: 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Parkin-mediated protection of dopaminergic neurons in a chronic MPTP-minipump mouse model of Parkinson disease.2011
- Author(s)
  Yasuda T, Miyake K, Takada M
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: 70 Pages: 686-697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] Activated K-Ras protein accelerates human MLL/AF4-induced leukemo-lymphomogenicity in a transgenic mouse model2011
- Author(s)
  Tamai H, Miyake K, Takatori M, Miyake N Yamaguchi H, Dan K, Shimada T, Inokuchi K.
- Journal Title
  
  Leukemia
  
  Volume: 25 Pages: 888-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Activated K-Ras protein accelerates humanMLL/AF4-inducedleukemo-lymphomogenicity in a transgenic mouse model.2011
- Author(s)
  Tamai H, Miyake K, Takatori M(8 人、2 番目)
- Journal Title
  
  Leukemia
  
  Volume: 25 Pages: 888-891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] Parkin-mediated protection of dopaminergic neurons in a chronic MPTP-minipump mouse model of Parkinson disease2011
- Author(s)
  Yasuda T, Hayakawa H, Nihira T, Ren YR, Nakata Y, Nagai M, Hattori N, Miyake K, Takada M, Shimada T, Mizuno Y, Mochizuki H.
- Journal Title
  
  J Neuropathol Exp Neurol
  
  Volume: 70 Pages: 686-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Importance of c-kit mutation detection method sensitivity in prognostic analyses of t(8;21)(q22;q22) acute myeloid leukemia.2011
- Author(s)
  Wakita S, Yamaguchi H, Miyake K,Mitamura Y, Kosaka F, Dan K, Inokuchi K
- Journal Title
  
  Leukemia
  
  Volume: 25 Pages: 1423-1432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] Global gene transfer into the CNS across the BBB after neonatal systemic delivery of single-stranded AAV vectors.2011
- Author(s)
  Miyake, N., Miyake, K., Yamamoto, M., Hirai, Y., Shimada, T.
- Journal Title
  
  Brain Res.
  
  Volume: 1389 Pages: 19-26
- Data Source
  KAKENHI-PROJECT-22390212
[Journal Article] Importance of c-kit mutation detection method sensitivity in prognostic analyses of t(8;21)(q22;q22) acute myeloid leukemia2011
- Author(s)
  Wakita S, Yamaguchi H, Miyake K, Mitamura Y, Kosaka F, Dan K, Inokuchi K.
- Journal Title
  
  Leukemia
  
  Volume: 25 Pages: 1423-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591554
[Journal Article] Global gene transfer into the CNS across the BBB after neonatal systemic delivery of single-stranded AAV vectors2011
- Author(s)
  Miyake, N.
- Journal Title
  
  Brain Res.
  
  Volume: 1389 Pages: 19-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390212
[Journal Article] Resistance of MLL-AFF1-positive acute lymphoblastic leukemia to tumor necrosis factor-alpha is mediated by S100A6 up-regulation.2011
- Author(s)
  Tamai H, Miyake K, Yamaguchi H
- Journal Title
  
  Blood Cancer Journal
  
  Volume: 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] Global gene transfer into the CNS across the BBB after neonatal systemic delivery of single-stranded AAV vectors.2011
- Author(s)
  Noriko Miyake
- Journal Title
  
  Brain Research
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591234
[Journal Article] Successful treatment of metachromatic leukodystrophy using bone marrow tnsplantation of HoxB4 oerexpressing clls.2010
- Author(s)
  Miyake N, Miyake K, Karlsson S, Shimada T
- Journal Title
  
  Mol. Ther. 18
  
  Pages: 1373-1378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591234
[Journal Article] Adeno-associated vector (type8)-mediated expression of soluble Flt-1 efficiently inhibits neovascularization in a murine choroidalneovascularization model.2010
- Author(s)
  Igarashi, T., Miyake, K., Masuda, I., Takahashi, H., Shimada, T.
- Journal Title
  
  Hum. Gene Ther.
  
  Volume: 21 Pages: 631-637
- Data Source
  KAKENHI-PROJECT-22390212
[Journal Article] Successful treatment of metachromatic leukodystrophy using bone marrow transplantation of HoxB4 overexpressing cells.2010
- Author(s)
  Noriko Miyake
- Journal Title
  
  Molecular Therapy
  
  Volume: 18 Pages: 1373-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591234
[Journal Article] Rescue of severe infantile hypophosphatasia mice by AAV-mediated sustained expression of soluble alkaline phosphatase.2010
- Author(s)
  Matsumoto T, Miyake K, Yamamoto S
- Journal Title
  
  Hum Gene Ther
  
  Volume: 22 Pages: 1355-1364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] Successful treatment of metachromatic leukodystrophy using bone marrow tnsplantation of HoxB4 oerexpressing clls.2010
- Author(s)
  Miyake N, Miyake K, Karlsson S, Shimada T
- Journal Title
  
  Mol. Ther. 18
  
  Pages: 1373-1378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591265
[Journal Article] Circadian disruption accelerates tumor growth and angio/stromagenesis through a Wnt signaling pathway.2010
- Author(s)
  Yasuniwa, Y., Izumi, H., Wang, K-Y., Shimajiri, S., Sasaguri, Y., Kawai, K., Kasai, H., Shimada, T., Miyake,. K., Kashiwagi, E., Hirano, G., Kidani, A.,Akiyama, M., Han, B., Wu, Y., Ieiri, I., Higuchi, S., Kohno, K.
- Journal Title
  
  PloS ONE
  
  Volume: 5
- Data Source
  KAKENHI-PROJECT-22390212
[Journal Article] Circadian disruption accelerates tumor growth andangio/stromagenesis through a Wntsignaling pathway.2010
- Author(s)
  Yasuniwa Y, Miyake K, Kashiwagi E
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] Successful treatment of metachromatic leukodystrophy using bone marrow transplantation of HoxB4 overexpressing cells.2010
- Author(s)
  Miyake, N., Miyake, K., Karlsson, S., Shimada, T.
- Journal Title
  
  Mol. Ther.
  
  Volume: 18 Pages: 1373-1378
- Data Source
  KAKENHI-PROJECT-22390212
[Journal Article] Adeno-associated vector (type 8)-mediated expression of soluble Flt-1 efficiently inhibits neovascularization in a murine choroidal neovascularization model.2010
- Author(s)
  Igarashi T, Miyake K, Masuda I, Takahashi H, Shimada T
- Journal Title
  
  Hum Gene Ther. 21
  
  Pages: 631-637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591265
[Journal Article] Successful treatment of metachromatic leukodystrophy using bone marrow transplantation of HoxB4 overexpressing cells2010
- Author(s)
  Miyake N, Miyake K, et al.
- Journal Title
  
  Molecular Therapy
  
  Volume: 18 Pages: 1373-1378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591265
[Journal Article] Basic and clinical studies on functional RNA molecules for advanced medical technologies2010
- Author(s)
  Takizawa T, Miyake K, et al.
- Journal Title
  
  J Nippon Med Sch.
  
  Volume: 77 Pages: 71-79
- NAID
  130004147041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591265
[Journal Article] RPS19 deficiency leads to reduced proliferation and increased apoptosis but does not affect terminal erythroid differentiation in a cell line model ofDiamond-Blackfan anemia.2010
- Author(s)
  Miyake K, Utsugisawa T, Flygare J,Kiefer T, Hamaguchi I, Richter J, Karlsson S
- Journal Title
  
  Stem Cells
  
  Volume: 26 Pages: 323-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] Basic and clinical studies on functional RNA molecules for advanced medical technologies.2010
- Author(s)
  Takizawa T, Gemma A, Ui-Tei K, Aizawa Y, Sadovsky Y, Robinson JM, Seike M, Miyake K
- Journal Title
  
  J Nippon Med Sch. 77
  
  Pages: 71-79
- NAID
  130004147041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591265
[Journal Article] Successful treatment of metachromatic leukodystrophy using bone marrow transplantation of HoxB4 overexpressing cells.2010
- Author(s)
  Miyake N, Miyake K, Karlsson S, Shimada T
- Journal Title
  
  Mol Ther
  
  Volume: 18 Pages: 1373-1378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591444
[Journal Article] Successful treatment of metachromatic leukodystrophy using bone marrow transplantation of HoxB4 overexpressing cells.2010
- Author(s)
  Miyake, N.
- Journal Title
  
  Mol.Ther.
  
  Volume: 18 Pages: 1373-1378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390212
[Journal Article] Global Diffuse Distribution in the Brain and Efficient Gene Delivery to the Dorsal Root Ganglia by Intrathecal Injection of AAV1 Vector2009
- Author(s)
  Iwamoto, N., Watanabe, A., Yamamoto, M., Miyake, N., Kurai, T., Teramoto, A., Shimada, T.
- Journal Title
  
  J.Gene Med. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Global diffuse distribution in the brain and efficient gene delivery to the dorsal root ganglia by intrathecal injection of adeno-associated viral vector serotype 1.2009
- Author(s)
  Iwamoto N, Watanabe A, Yamamoto M, Miyake N, Kurai T, Teramoto A, Shimada T
- Journal Title
  
  J Gene Med. 11
  
  Pages: 498-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591234
[Journal Article] RPS19 deficiency leads to reduced proliferation and increased apoptosis but does not affect terminal eiythroid differentiation in a cell line model of Diamond -Blackfan anemia2008
- Author(s)
  Miyake, K
- Journal Title
  
  Stem Cells 26
  
  Pages: 323-329
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591204
[Journal Article] RPS19 deficiency leads to reduced proliferation and increased apoptosis but does not affect terminal erythroid differentiation in a cell line model of Diamond-Blackfan anemia.2008
- Author(s)
  Miyake K
- Journal Title
  
  Stem Cells 26
  
  Pages: 323-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591204
[Journal Article] RPS 19 deficiency leads to reduced proliferation and increased apoptosis but does not affect terminal erythroid differentiation in a cell line model of Diamond-Blackfan anemia2008
- Author(s)
  Miyake K
- Journal Title
  
  Stem Cells 26
  
  Pages: 323-329
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591204
[Journal Article] Development of targeted gene transfer into human primary T lymphocytes and macrophages using high-titer recombinant HIV vectors2007
- Author(s)
  Miyake, K., Miyake, N., Shimada, T.
- Journal Title
  
  J.Biotech. 129
  
  Pages: 532-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Systemic Cancer Gene Therapy Using Adeno-associated Virus Type 1 Vector Expressing MDA-7/IL242007
- Author(s)
  Tahara, I., Miyake, K., Hanawa, H., Kurai, T., Hirai, Y., Ishizaki, M., Uchida, E., Tajiri, T., Shimada, T.
- Journal Title
  
  Mol Ther. 15
  
  Pages: 1805-1811
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Development of targeted gene transfer into human primary T lymphocytes and macrophages using high-titer recombinant HIV vectors2007
- Author(s)
  Miyake, K
- Journal Title
  
  J. Biotechnol 129
  
  Pages: 532-538
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591204
[Journal Article] HIV vector mediated targeted suicide gene therapy for adult T-cell leukemia2007
- Author(s)
  Miyake K
- Journal Title
  
  Gene Ther. 14
  
  Pages: 1662-1667
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591204
[Journal Article] Development of targeted gene transfer into human primary T lymphocytes and macrophages using high-titer recombinant HIV vectors2007
- Author(s)
  Miyake K
- Journal Title
  
  J Biotechnol. 129
  
  Pages: 532-538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591204
[Journal Article] Development of targeted gene transfer into human primary T lymphocytes and macrophages using high-titer recombinant HIV vectors.2007
- Author(s)
  Miyake,K., et al.
- Journal Title
  
  J.Biotech. 129
  
  Pages: 532-8
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] HIV vector mediated targeted suicide gene therapy for adult T-cell leukemia2007
- Author(s)
  Miyake, K
- Journal Title
  
  Gene Then 14
  
  Pages: 1662-1667
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591204
[Journal Article] HIV vector mediated targeted suicide gene therapy for adult T-cell leukemia2007
- Author(s)
  Miyake, K., Inokuchi, K., Miyake, N., Dan, K., shimada, T.
- Journal Title
  
  Gene Ther. 14
  
  Pages: 1662-1667
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Human RPS19, the gene mutated in Diamond-Blackfan anemia, encodes a ribosomal protein required for the maturation of 40S ribosomal subunits2007
- Author(s)
  Flygare J, Aspesi A, Miyake K, et al.
- Journal Title
  
  Blood 109・3
  
  Pages: 980-986
- Data Source
  KAKENHI-PROJECT-18591204
[Journal Article] Development of targeted gene transfer into human primary T lymphocytes and macrophages using high-titer recombinant HIV vectors2007
- Author(s)
  Miyake K
- Journal Title
  
  J.Biotechnol. 129
  
  Pages: 532-538
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591204
[Journal Article] HIV vector mediated targeted suicide gene therapy for adult T-Cell leukemiz.2007
- Author(s)
  Miyake,K., et al.
- Journal Title
  
  Gene Ther. 14
  
  Pages: 1662-1667
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Erythropoiesis in the Rps19 disrupted mouse : Analysis of erythropoietin response and biochemical markers for Diamond-Blackfan anemia2006
- Author(s)
  MatssonH, Davey EJ, Miyake K, et al.
- Journal Title
  
  Blood Cells Mol Dis. 36・2
  
  Pages: 259-264
- Data Source
  KAKENHI-PROJECT-18591204
[Journal Article] Ex vivo cell-mediated gene therapy for metachromatic leukodystrophy using neurospheres2006
- Author(s)
  Kawabata, K., Migita, M., Mochizuki, H., Miyake, K., Igarashi, T., Fukunaga, Y., Shimada, T.
- Journal Title
  
  Brain Res. 1094
  
  Pages: 13-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Mutations of the p53 cDNA sequence introduced by the retroviral vector2006
- Author(s)
  Su, S., Watanabe, A., Yamamoto, M., Nakajima, E., Miyake, K., Shimada, T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 340
  
  Pages: 567-572
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Antiangiogenic gene therapy of myeloproliferative disease developed in transgenic mice expressing p230 ber/abl.2005
- Author(s)
  Miyake,K., et al.
- Journal Title
  
  Gene Ther. 12
  
  Pages: 541-545
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] HIV vector mediated intra-articular expression of angiostatin inhibits progression of collagen-induced arthritis in mice2005
- Author(s)
  Kato, K., Miyake, K., Igarashi, T., Yoshino, S., Shimada, T.
- Journal Title
  
  Rheumatol.Int. 25
  
  Pages: 522-529
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Antiangiogenic gene therapy of myeloproliferative disease developed in transgenic mice expressing P230 ber/abl2005
- Author(s)
  Miyake, K., Inokuchi, K., Miyake, N., Dan, K., Shimada, T.
- Journal Title
  
  Gene Ther. 12
  
  Pages: 541-545
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Adeno-associated virus vector-mediated anti-angiogenic gene therapy for collagen-induced arthritis in mice2005
- Author(s)
  Takahashi, H., Kato, K., Miyake, K., Yoshino, S., Shimada, T.
- Journal Title
  
  Clin.Exp.Rheumatol. 23
  
  Pages: 7-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Adeno-associated virus vector-mediated anti-angiogenic gene therapy for collagen-induced arthritis in mice.2005
- Author(s)
  Takahashi H, Kato K, Miyake K, Shimada T et al.
- Journal Title
  
  Clinical and Experimental Rheumatology 23(in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591067
[Journal Article] Antiangiogenic gene therapy of myeloproliferative disease developed in transgenic mice expressing P230 ber/abl.2005
- Author(s)
  Miyake, K., Inokuchi, K., et al.
- Journal Title
  
  Gene Ther. (in press)
- Data Source
  KAKENHI-PROJECT-12217142
[Journal Article] Human immunodeficiency virus vector-mediated intra-articular expression of angiostatin inhibits progression of collagen-induced arthritis in mice2004
- Author(s)
  Kato K, Miyake K, Shimada T et al.
- Journal Title
  
  Rheumatology International 15 June(Online First)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591067
[Journal Article] Adeno-associated viral vector mediated expression on endostatin inhibits tumor growth and metastasis in an orthotropic pancreatic cancer model in hamsters.2004
- Author(s)
  Noro, T., Miyake, K., et al.
- Journal Title
  
  Cancer Res. 64
  
  Pages: 7486-7490
- Data Source
  KAKENHI-PROJECT-14370253
[Journal Article] Human immunodeficiency virus vector-mediated intra-articular expression of angiostatin inhibits progression of collagen-induced arthritis in mice2004
- Author(s)
  Kato K, Miyake K, Shimada T et al.
- Journal Title
  
  Rheumatology International 15June(Online First)
- Data Source
  KAKENHI-PROJECT-15591067
[Journal Article] HIV vector mediated intra-articular expression of angiostatin inhibits progression of collagen-induced arthritis in mice.2004
- Author(s)
  Kato, K., Miyake, K., et al.
- Journal Title
  
  Rheumatol.Int. (in press)
- Data Source
  KAKENHI-PROJECT-12217142
[Journal Article] Human immunodeficiency virus vector-mediated intra-articular expression of angiostatin inhibits progression of collagen-induced arthritis in mice.2004
- Author(s)
  Kato k, Miyake K, Shimada T et al.
- Journal Title
  
  Rheumatology International. online first 15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591067
[Journal Article] Adeno-associated viral vector mediated expression on endostatin inhibits tumor growth and metastasis in an orthotropic pancreatic cancer model in hamsters.2004
- Author(s)
  Noro, T., Miyake, K., et al.
- Journal Title
  
  Cancer Res. 64
  
  Pages: 7486-7490
- Data Source
  KAKENHI-PROJECT-12217142
[Journal Article] Lentivirus-mediated expression of angiostatin efficiently inhibits neovascularization in a murine proliferative retinopathy model.2003
- Author(s)
  Igarashi, T., Miyake, K., et al.
- Journal Title
  
  Gene Ther. 10
  
  Pages: 219-226
- Data Source
  KAKENHI-PROJECT-14370253
[Journal Article] Lentivirus-mediated expression of angiostatin efficiently inhibits neovascularization in a murine proliferative retinopathy model.2003
- Author(s)
  Igarashi, T., Miyake, K., Kato, K., Watanabe, A., Ishizaki, M., Ohara, K., Shimada, T.
- Journal Title
  
  Gene Ther. 10
  
  Pages: 219-226
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370253
[Journal Article] Lentivirus-mediated expression of angiostatin efficiently inhibits neovascularization in a murine proliferative retinopathy model.2003
- Author(s)
  Igarashi, T., Miyake, K., et al.
- Journal Title
  
  Gene Ther. 10
  
  Pages: 219-226
- Data Source
  KAKENHI-PROJECT-12217142
[Journal Article] New strategy for in vivo transgene expression in corneal epithelial progenitor cells.2002
- Author(s)
  Igarashi, T., Miyake, K., Suzuki, N., Kato, K., Takahashi, H., Ohara, K., Shimada, T.
- Journal Title
  
  Current Eye Res. 24
  
  Pages: 46-50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370253
[Journal Article] New strategy for in vivo transgene expression in corneal epithelial progenitor cells.2002
- Author(s)
  Igarashi, T., Miyake, K., et al.
- Journal Title
  
  Current Eye Res. 24
  
  Pages: 46-50
- Data Source
  KAKENHI-PROJECT-14370253
[Journal Article] Cyclical mechanical stretch enhances degranulation and IL-4 secretion in RBL-2H3 mast cells.
- Author(s)
  Komiyama, H., Miyake, K., Asai, K., Mizuno, K., Shimada, T.
- Journal Title
  
  Cell Biochem. Function
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] 異染性白質ジストロフィーの遺伝子治療2022
- Author(s)
  三宅紀子, 三宅弘一, 酒井真志人, 島田隆
- Organizer
  The 28th Annual Meeting of Japan Society of Gene Therapy
- Invited
- Data Source
  KAKENHI-PROJECT-18K07859
[Presentation] Intravitreal injection of AAV vector in cynomolgus monkeys affects neutralizing antibody titer against AAV in the serum2018
- Author(s)
  Tsutomu Igarashi, Kazuhisa Takahashi, Koichi Miyake, Maika Kobayashi, Chiemi Yaguchi, Noriko Miyake, Shuhei Kameya, Hiroshi Takahashi, Takashi Okada
- Organizer
  The 24th Annual Meeting of Japan Society of Gene Therapy
- Data Source
  KAKENHI-PROJECT-15K09604
[Presentation] Intravitreal injection of AAV vector in cynomolgus monkeys affects neutralizing antibody titer against AAV in the serum.2018
- Author(s)
  Tsutomu Igarashi, Kazuhisa Takahashi, Koichi Miyake, Maika Kobayashi, Chiemi Yaguchi, Noriko Miyake, Shuhei Kameya, Hiroshi Takahashi, Takashi Okada
- Organizer
  The 24th Annual Meeting of Japan Society of Gene Therapy
- Data Source
  KAKENHI-PROJECT-15K09605
[Presentation] Direct comparison between single-stranded and self-complementary type 9 AAV vector to treat adult MLD model mice by intravenous injection2018
- Author(s)
  Noriko Miyake, Koichi Miyake, Motoko Yamamoto, Takashi Shimada, Takashi Okada
- Organizer
  The 2４th Annual Meeting of Japan Society of Gene Therapy
- Data Source
  KAKENHI-PROJECT-18K07859
[Presentation] Direct comparison between single-stranded and self-complementary type 9 AAV vector to treat adult MLD model mice by intravenous injection.2018
- Author(s)
  Noriko Miyake, Koichi Miyake, Motoko Yamamoto, Takashi Shimada, Takashi Okada.
- Organizer
  The 24th Annual Meeting of Japan Society of Gene Therapy
- Data Source
  KAKENHI-PROJECT-15K09605
[Presentation] Direct comparison between single-stranded and self-complementary type 9 AAV vector to treat adult MLD model mice by intravenous injection2018
- Author(s)
  Noriko Miyake, Koichi Miyake, Motoko Yamamoto, Takashi Shimada, Takashi Okada
- Organizer
  The 24th Annual Meeting of Japan Society of Gene Therapy
- Data Source
  KAKENHI-PROJECT-15K09604
[Presentation] Intravitreal injection of AAV vector in cynomolgus monkeys affects neutralizing antibody titer against AAV in the serum2018
- Author(s)
  Tsutomu Igarashi, Kazuhisa Takahashi, Koichi Miyake, Maika Kobayashi, Chiemi Yaguchi, Noriko Miyake, Shuhei Kameya, Hiroshi Takahashi, Takashi Okada
- Organizer
  The 2４th Annual Meeting of Japan Society of Gene Therapy
- Data Source
  KAKENHI-PROJECT-18K07859
[Presentation] DKCの診断におけるTERT遺伝子変異の機能解析の重要性2017
- Author(s)
  Kazuki Terada, Hiroki Yamaguchi, Koichi Miyake, Noriko Miyake, Yoshiki Osaki, Takashi Okada, Seiji Kojima, Etsuro Ito, Koiti Inokuchi.
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09832
[Presentation] Why are scAAV9 vectors able to pass through the BBB but not ssAAV9? ; The difference between the ssAAV9 and scAAV9 vector in transduction of CNS by intravenous injection.2017
- Author(s)
  Noriko Miyake, Koichi Miyake, Motoko Yamamoto, Takashi Shimada, Takashi Okada
- Organizer
  20th Annual Meeting of the American Society of Gene & Cell Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09604
[Presentation] Why are scAAV9 vectors able to transduce the CNS but not ssAAV9? ; The difference between the ssAAV9 and scAAV9 vector in transduction of CNS by intravenous injection.2017
- Author(s)
  Noriko Miyake, Koichi Miyake, Motoko Yamamoto, Takashi Shimada, Takashi Okada
- Organizer
  The 23th Annual Meeting of Japan Society of Gene Therapy
- Data Source
  KAKENHI-PROJECT-15K09604
[Presentation] ssAAV vectors are able to pass through the BBB as same as dsAAV2016
- Author(s)
  Noriko Miyake, Koichi Miyake, Motoko Yamamoto, Takashi Shimada, Takashi Okada
- Organizer
  The 22th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  東京
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-15K09604
[Presentation] Successful treatment of neonatal metachromatic leukodystrophy model mice by low dose of self-complementary AAV type 9 vector expressing ASA2016
- Author(s)
  Miyake N, Miyake K, Yamamoto M, Shimada T, Okada T
- Organizer
  19th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Washington DC)
- Year and Date
  2016-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09604
[Presentation] 異染性白質ジストロフィー(MLD)の遺伝子治療基盤研究2015
- Author(s)
  三宅　紀子、三宅　弘一、山本　基子、島田　隆、岡田　尚巳
- Organizer
  第20 回日本ライソゾーム病研究会
- Place of Presentation
  東京(慈恵医科大学）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K09604
[Presentation] Successful treatment of neonatal metachromatic leukodystrophy model mice by　 intravenous injection of self-complementary AAV type 9 vector expressing ASA2015
- Author(s)
  Noriko Miyake, Koichi Miyake, Motoko Yamamoto, Takashi Shimada, Takashi Okada
- Organizer
  The 21th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  大阪（国際会議場）
- Year and Date
  2015-07-24
- Data Source
  KAKENHI-PROJECT-15K09604
[Presentation] Prolonged Survival and Improved Phenotypes of Lethal Hypophosphatasia Model Mice By Adeno-Associated Virus Mediated Muscle Transduction of Bone-Targeted Alkaline Phosphatase.2015
- Author(s)
  Nakamura A, Miyake K, Watanabe A, Hirai Y, Miyake N, Iijima O, Adachi K, Kinoshita H, Noguchi T, Abe S, Shimada T, Okada T.
- Organizer
  18th American Society of Gene and Cell Therapy Annual Meeting
- Place of Presentation
  Hyatt Regency New Orleans（New Orleans, LA）
- Year and Date
  2015-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461564
[Presentation] Successful treatment of neonatal metachromatic leukodystrophy model mice by　 intravenous injection of self-complementary AAV type 9 vector expressing ASA2015
- Author(s)
  Noriko Miyake, Koichi Miyake, Motoko Yamamoto, Takashi Shimada, Takashi Okada
- Organizer
  The 21th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  大阪（国際会議場）
- Year and Date
  2015-07-24
- Data Source
  KAKENHI-PROJECT-26461596
[Presentation] Gene therapy to rescue lethal hypophosphatasia model mice by adeno-associated virus-mediated muscle transduction of bone-targeted alkaline phosphatase.2015
- Author(s)
  Nakamura A, Miyake K, Watanabe A, Hirai Y, Iijima O, Miyake N, Adachi K, Nitahara-Kasahara Y, Kinoshita H, Noguchi T, Abe S, Narisawa S, Millan JL, Shimada T, Okada T.
- Organizer
  第21回日本遺伝子治療学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府）
- Year and Date
  2015-07-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461564
[Presentation] The D816V c-kit mutation confers higher proliferation activity by JAK-STAT and Src family kinase pathways compared to N822K c-kit mutation in core-binding factor acute myeloid leukemia.2015
- Author(s)
  Ikuko Omori1, Hiroki Yamaguchi1, Tomoaki Kitano, Noriko Miyake, Koichi Miyake, Kazuo Dan, Koiti Inokuchi.
- Organizer
  20th Congress of European Hematology Association
- Place of Presentation
  Austria, Vienna
- Year and Date
  2015-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461596
[Presentation] Long-term enzyme replacement therapy for hypophosphatasia by muscle-directed expression of bone targeted alkaline phosphatase using self-complementary AAV8 vector.2015
- Author(s)
  Nakamura-Takahashi A, Miyake K, Watanabe A, Hirai Y, Iijima O, Miyake N, Adachi K, Nitahara-Kasahara Y, Kinoshita H, Noguchi T, Abe S, Narisawa S, Millan JL, Shimada T, Okada T.
- Organizer
  第11回ALPS研究会
- Place of Presentation
  日本女子大学（東京都）
- Year and Date
  2015-07-18
- Data Source
  KAKENHI-PROJECT-25461564
[Presentation] アデノ随伴ウイルスベクターの脳室内注入による異染性白色ジストロフィーモデルマウスの遺伝子治療2015
- Author(s)
  廣中浩平,山崎吉之,平井幸彦, 山本基子, 三宅紀子, 三宅弘一, 森田明夫, 島田隆, 岡田尚巳
- Organizer
  第20 回日本ライソゾーム病研究会
- Place of Presentation
  東京(慈恵医科大学）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K09604
[Presentation] Rescue of lethal murine hypophosphatasia using genetically modified bone marrow cells expressing bone-targeted tissue non-specific alkaline phosphatase.2015
- Author(s)
  Iijima O, Miyake K, Watanabe A, Miyake N, Igarashi T, Kanokoda C, Nakamura-Takahashi A, Kinoshita H, Noguchi T, Abe S, Narisawa S, Millan JL, Okada T, Shimada T.
- Organizer
  第11回ALPS研究会
- Place of Presentation
  日本女子大学（東京都）
- Year and Date
  2015-07-18
- Data Source
  KAKENHI-PROJECT-25461564
[Presentation] Minimally invasive gene therapy of MLD model mice by intrathecal and intravenous injection of AAV9 vector.2014
- Author(s)
  Noriko Miyake, Koichi Miyake, and Takashi Shimada
- Organizer
  10th WORLDSymposium™ 2014
- Place of Presentation
  San Diego,CA
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] Successful Treatment of Adult MLD Model Mice By Intravenous Injection of Self-Complementary Type 9 AAV Vector Expressing ASA2014
- Author(s)
  Miyake N, Miyake K, Yamamoto M and Shimada T.
- Organizer
  17th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Minimally invasive gene therapy of MLD model mice by intrathecal and intravenous injection of AAV9 vector2014
- Author(s)
  Miyake N, Miyake K, and Shimada T.
- Organizer
  10th WORLDSymposium™
- Place of Presentation
  San Diego,CA
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Minimally invasive gene therapy of MLD model mice by intrathecal and intravenous injection of AAV9 vector2014
- Author(s)
  Miyake N, Miyake K, Shimada T.
- Organizer
  10th WORLDSymposium™ 2014
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] miR-7aは電位依存性ナトリウムチャネルβ2サブユニットの発現調節により慢性期神経障害性疼痛を緩和する2013
- Author(s)
  坂井　敦、齋藤文仁、三宅紀子、三宅弘一、島田　隆、鈴木秀典
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] siRNA Targeting Vascular Endothelial Growth Factor by adeno-associated vector (type 8) efficiently inhibits Neovascularization in a Murine Choroidal Neovascularization Model2013
- Author(s)
  Igarashi T, Miyake N, Iijima O, Yaguchi C, Shimada T, Takahashi H, Miyake K.
- Organizer
  The 19th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Okayama,Japan
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Adeno−Associated Vector (Type 8)−Mediated Expression of siRNA Targeting Vascular Endothelial Growth Factor Efficiently Inhibits Neovascularization in a Murine Choroidal Neovascularization Model2013
- Author(s)
  Igarashi T, Miyake K, Miyake N, Iijima O, Yaguchi C, Shimada T and Takahashi H.
- Organizer
  16th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Salt Lake City, Utah
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Long−Term Secretion of Arylsulfatase A without Antibody Formation after AAV Mediated Neonatal Gene Transfer into MLD Model Mice2013
- Author(s)
  Miyake N, Miyake K, Yamamoto M and Shimada T.
- Organizer
  16th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Salt Lake City, Utah
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Bone marrow cell based enzyme replacement prolongs survival and improves disease phenotypes in a mouse model of lethal hypophosphatasia2013
- Author(s)
  Iijima O, Miyake K, Nakamura A, Igarashi T, Kanokoda C, Watanabe A, Shimada T
- Organizer
  55th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  Ernest N. Morial Convention Center (New Orleans, LA, USA)
- Data Source
  KAKENHI-PROJECT-25461564
[Presentation] Tolerance induction to arylsulfatase A by AAV mediated neonatal gene transfer into MLD model mice2013
- Author(s)
  Miyake N, Miyake K, Yamamoto M, Shimada T.
- Organizer
  The 19th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Okayama, Japan
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Disruption of metabotropic glutamate receptor signaling and rescue through intravascular administration of AAV9 in a mouse model of spinocerebellar ataxia type 3.2013
- Author(s)
  Konno A, Shuavaev AN, Miyake N, Miyake K, Yanagi S, Shimada T, Hirai H.
- Organizer
  The 19th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Okayama
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] Long−Term Secretion of Arylsulfatase A without Antibody Formation after AAV Mediated Neonatal Gene Transfer into MLD Model Mice.2013
- Author(s)
  Miyake N, Miyake K, Yamamoto M and Shimada T.
- Organizer
  16th Annual Meeting of the American Society of Gene & Cell Therapy.
- Place of Presentation
  Salt Lake City, Utah
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] Adeno－Associated Vector (Type 8)－Mediated Expression of siRNA Targeting Vascular Endothelial Growth Factor Efficiently Inhibits Neovascularization in a Murine Choroidal Neovascularization Model2013
- Author(s)
  Igarashi T, Miyake K, Miyake N, Iijima O, Yaguchi C, Shimada T, Takahashi H.
- Organizer
  16th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Salt Lake City, Utah, USA
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Adeno−Associated Vector (Type 8)−Mediated Expression of siRNA Targeting Vascular Endothelial Growth Factor Efficiently Inhibits Neovascularization in a Murine Choroidal Neovascularization Model.2013
- Author(s)
  Igarashi T, Miyake K, Miyake N, Iijima O, Yaguchi C, Shimada T and Takahashi H.
- Organizer
  16th Annual Meeting of the American Society of Gene & Cell Therapy.
- Place of Presentation
  Salt Lake City, Utah
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] Robust and cell type-specific transgene expression by applying tetracycline-controlled system to AAV9.2013
- Author(s)
  Yamaguchi T, Konno A, Miyake N, Miyake K, Shimada T, Hirai H.
- Organizer
  The 19th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Okayama
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] Long－Term Secretion of Arylsulfatase A without Antibody Formation after AAV Mediated Neonatal Gene Transfer into MLD Model Mice2013
- Author(s)
  Miyake N, Miyake K, Yamamoto M, Shimada T.
- Organizer
  16th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Salt Lake City, Utah, USA
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] 低フォスファターゼ症マウスに対するex vivo遺伝子治療法の検討2013
- Author(s)
  飯島　修、三宅弘一、中村有希、鹿子田千津、五十嵐勉、渡邉　淳、島田　隆
- Organizer
  第58回日本人類遺伝学会
- Place of Presentation
  江陽グランドホテル（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-25461564
[Presentation] Targeted Gene Transfer into the Ependymal Cells and Long-Term Enzyme Replacement in the CSF by Intraventricular Injection of AAV Vector Serotype 12013
- Author(s)
  Yamazaki Y, Hironaka K, Hirai Y, Miyake K, Shimada T.
- Organizer
  16th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Salt Lake City, Utah, USA
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Tolerance induction to arylsulfatase A by AAV mediated neonatal gene transfer into MLD model mice.2013
- Author(s)
  Miyake N, Miyake K, Yamamoto M and Shimada T.
- Organizer
  The 19th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Okayama
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] siRNA Targeting Vascular Endothelial Growth Factor by adeno-associated vector (type 8) efficiently inhibits Neovascularization in a Murine Choroidal Neovascularization Model.2013
- Author(s)
  Igarashi T, Miyake N, Iijima O, Yaguchi C, Shimada T, Takahashi H and Miyake K.
- Organizer
  The 19th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Okayama
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] AAV9 mediated gene therapy of MLD model mice.2012
- Author(s)
  Miyake, N., Miyake, K., Sakai, A., Yamamoto, M., Endo, A., Suzuki, H., Shimada, T.
- Organizer
  20th Annual Meeting of the European Society of Gene & Cell Therapy.
- Place of Presentation
  Versailles, France
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Ex vivo gene therapy of severe infantile hypophosphatasia model mice using lentiviral transduced bone marrow cells2012
- Author(s)
  Iijima O, Sugano H, Watanabe A, Miyake K, Shimada T
- Organizer
  6th Alkaline Phosphatasie and Hypophosphatasia International Symposium
- Place of Presentation
  Huningue, France
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] DRG神経におけるmiR-7a過剰発現は神経障害性疼痛を特異的に抑制する2012
- Author(s)
  坂井敦、齋藤文仁、三宅紀子、三宅弘一、島田隆、鈴木秀典
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] Gene therapy of adult MLD model mice by intrathecal administration of type 9 AAV vector2012
- Author(s)
  Noriko Miyake, Koichi Miyake, Atsushi Sakai, Motoko Yamamoto, Ayumi Endo, Hidenori Suzuki, Takashi Shimada
- Organizer
  15th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Philadelphia, Pennsylvania
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] Gene therapy of adult MLD model mice by intrathecal administration of type 9 AAV vector2012
- Author(s)
  Miyake N, Miyake K, Sakai A, Yamamoto M, Endo A, Suzuki H, Shimada T
- Organizer
  第4回国際ライソゾーム病フォーラム・第17回日本ライソゾーム病研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] AAV9 mediated gene therapy of MLD model mice2012
- Author(s)
  Noriko Miyake, Koichi Miyake, Atsushi Sakai, Motoko Yamamoto, Ayumi Endo, Hidenori Suzuki, Takashi Shimada
- Organizer
  20th Annual Meeting of the European Society of Gene & Cell Therapy
- Place of Presentation
  Versailles, France
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] Successful treatment of adult MLD model mice by intrathecal administration of type 9 AAV vector.2012
- Author(s)
  Miyake N, Miyake K
- Organizer
  The 18th Annual Meeting of Japan Society ofGene Therapy
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] Rescue of lethal hypophosphatasia mice by neonatal ex vivo gene therapy using lentivirally transduced bone marrow cells.2012
- Author(s)
  Iijima O, Miyake K
- Organizer
  54th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  Atlanta,USA
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] Successful treatment of adult MLD model mice by intrathecal administration of AAV9 vector2012
- Author(s)
  Noriko Miyake, Koichi Miyake, Atsushi Sakai, Motoko Yamamoto, Ayumi Endo, Hidenori Suzuki, Takashi Shimada
- Organizer
  The 18th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Kumamoto
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] Gene therapy of adult MLD model mice by intrathecal administration of type 9 AAV vector2012
- Author(s)
  Miyake N, Miyake K, Sakai A, Yamamoto M, Endo A, Suzuki H, Shimada T
- Organizer
  15th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Successful gene therapy in utero for lethal murine hypophosphatasia.2012
- Author(s)
  Sugano H, Miyake K
- Organizer
  6th Alkaline Phosphatasie and Hypophosphatasia International Symposium
- Place of Presentation
  Huningue,France
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] Successful gene therapy in utero for lethal murine hypophosphatasia2012
- Author(s)
  Sugano H, Miyake K, Watanabe A, Iijima O, Narisawa S, Millán JL, Fukunaga Y, Shimada T
- Organizer
  6th Alkaline Phosphatasie and Hypophosphatasia International Symposium
- Place of Presentation
  Huningue, France
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Gene therapy of adult MLD model mice by intrathecal administration of type 9 AAV vector2012
- Author(s)
  Miyake N, Miyake K, Sakai A, Yamamoto M, Endo A, Suzuki H, and Shimada T.
- Organizer
  15th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Philadelphia, Pennsylvania
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] AAV9 mediated gene therapy of MLD model mice2012
- Author(s)
  Miyake N, Miyake K, Sakai A, Yamamoto M, Endo A, Suzuki H, and Shimada T.
- Organizer
  20th Annual Meeting of the European Society of Gene & Cell Therapy
- Place of Presentation
  Versailles, France
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Rescue of lethal hypophosphatasia mice by neonatal ex vivo gene therapy using lentivirally transduced bone marrow cells2012
- Author(s)
  Iijima O, Miyake K, Sugano H, Tsutomu I, Chizu K, Watanabe A, Shimada T
- Organizer
  54th American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Gene therapy of adult MLD model mice by intrathecal administration of type 9 AAV vector.2012
- Author(s)
  Miyake, N., Miyake, K., Sakai, A., Yamamoto, M., Endo, A., Suzuki, H., Shimada, T.
- Organizer
  15th Annual Meeting of the American Society of Gene & Cell Therapy.
- Place of Presentation
  Philadelphia, Pennsylvania
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Ex vivo gene therapy of severe infantile hypophosphatasia model mice using lentiviral transduced bone marrow cells2012
- Author(s)
  Iijima O, Sugano H, Watanabe A, Miyake K, Shimada T
- Organizer
  The 18th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Gene therapy of adult MLD model mice by intrathecal administration of type 9 AAV vector.2012
- Author(s)
  Miyake N, Miyake K
- Organizer
  第4回国際ライソゾーム病フォーラム・第17回日本ライソゾーム病研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] DRG神経におけるmiR-7a過剰発現は神経障害性疼痛を特異的に抑制する2012
- Author(s)
  坂井敦、齋藤文仁、三宅紀子、三宅弘一、島田隆、鈴木秀典
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Successful treatment of adult MLD model mice by intrathecal administration of type 9 AAV vector2012
- Author(s)
  Miyake N, Miyake K, Sakai A, Yamamoto M, Endo A, Suzuki H, Shimada T
- Organizer
  The 18th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Gene therapy of adult MLD model mice by intrathecal administration of type 9 AAV vector2012
- Author(s)
  Noriko Miyake, Koichi Miyake, Atsushi Sakai, Motoko Yamamoto, Ayumi Endo, Hidenori Suzuki, Takashi Shimada
- Organizer
  第4回国際ライソゾーム病フォーラム・第17回日本ライソゾーム病研究会
- Place of Presentation
  東京プリンスホテル
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] Gene therapy of adult MLD model mice by intrathecal administration of type 9 AAV vector.2012
- Author(s)
  Miyake N, Miyake K
- Organizer
  15th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] 骨髄細胞移植による低フォスファターゼ症のex vivo遺伝子治療2012
- Author(s)
  飯島修、菅野華子、鹿子田千津、渡邉淳、三宅弘一、島田隆
- Organizer
  第57回日本人類遺伝学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] AAV9 mediated gene therapy of MLD model mice.2012
- Author(s)
  Miyake N, Miyake K
- Organizer
  20th Annual Meeting of the European Society of Gene & Cell Therapy
- Place of Presentation
  Versailles, France
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] AAV Type 8 Mediated Bone-Targeted and Muscle Directed Neonatal Gene Therapy for Hypophosphatasia2011
- Author(s)
  Miyake, K.
- Organizer
  第17回日本遺伝子治療学会
- Place of Presentation
  福岡(ポスター)
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] AAV Type 8 Mediated Bone-Targeted and Muscle Directed Neonatal Gene Therapy for Hypophosphatasia.2011
- Author(s)
  Miyake K
- Organizer
  The17th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] Gene Therapy for MLD by Intrathecal Administration of Type 9 AAV Vector Expressing ASA2011
- Author(s)
  Miyake, N.
- Organizer
  第17回日本遺伝子治療学会
- Place of Presentation
  福岡
- Year and Date
  2011-07-17
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Development of cell targeting strategy using HIV vector pseudtyped with HIV envelope2011
- Author(s)
  Koichi Miyake, Takashi Shimada
- Organizer
  The 17th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Intrathecal Administration of Type 9 AAV Vector Expressing Arylsulfatase A Is Effective for Reduction of Sulfatide Storage but Not for Correction of Neurological Deficits in Adult Metachromatic Leukodystrophy Model Mice with Overt Neurological Symptoms2011
- Author(s)
  Miyake, N.
- Organizer
  14th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Seattle
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Gene Therapy for MLD by Intrathecal Administration of Type 9AAV Vector Expressing ASA.2011
- Author(s)
  Miyake N, Miyake K
- Organizer
  The 17th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] Direct Comparison of Administration Routes for AAV 8 Mediated Ocular Gene Therapy.2011
- Author(s)
  Igarashi, T., Miyake, K., Asakawa, N., Shimada, T., Takahashi, H.
- Organizer
  14th Annual Meeting of the American Society of Gene & Cell Therapy.
- Place of Presentation
  Seattle, WA
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] A single injection of AAV-8 vector expressing IL-24 efficiently suppressestumor growth mediated by multiple anti-tumor mechanisms in MLL/AF4 positive ALL model mice.2011
- Author(s)
  Tamai, H., Miyake, K., Yamaguchi, H., Inokuchi, K., Shimada, T., Dan, K.
- Organizer
  2011European Hematology AssociationCongress.
- Place of Presentation
  London
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Fetal Gene Therapy for Lethal Murine Hypophosphatasia.2011
- Author(s)
  Sugano, H., Matsumoto, T., Miyake, K., Watanabe, A., Narisawa, S.,Millan, J.L., Fukunaga, Y., Shimada, T.
- Organizer
  14th Annual Meeting of the American Society of Gene & Cell Therapy.
- Place of Presentation
  Seattle, WA
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Successful Treatment of Hypophosphatasia Model Mice by a Single Intramuscular Injection of AAV Type 8 Vector Expressing Tissue-Nonspecific Alkaline Phosphatase.2011
- Author(s)
  Matsumoto T, Miyake K
- Organizer
  14th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] Successful Treatment of Hypophosphatasia Model Mice by a Single Intramuscular Injection of AAV Type 8 Vector Expressing Tissue-Nonspecific Alkaline Phosphatase.2011
- Author(s)
  Matsumoto, T., Miyake, K., Miyake, N., Orimo, H., Narisawa, S., Millan, J.L. Fukunaga, Y., Shimada. T.
- Organizer
  14th Annual Meeting of the American Society of Gene & Cell Therapy.
- Place of Presentation
  Seattle, WA
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Development of cell targeting strategy using HIV vector pseudtyped with HIV envelope.2011
- Author(s)
  Miyake K
- Organizer
  The17th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] The effect and specific mechanisms of systemic gene therapy using AAV8-IL24 in MLL/AF4 Tg mice.2011
- Author(s)
  玉井勇人, 三宅弘一
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] Development of cell targeting strategy using HIV vector pseudtyped with HIV envelope2011
- Author(s)
  Miyake, K.
- Organizer
  第17回日本遺伝子治療学会
- Place of Presentation
  福岡
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] IntrathecalAdministration of Type 9 AAV Vector Expressing Arylsulfatase A Is Effective for Reduction of Sulfatide Storage but Not for Correction of Neurological Deficits in Adult Metachromatic Leukodystrophy Model Mice with Overt Neurological Symptoms.2011
- Author(s)
  Miyake, N., Miyake, K., Sakai, A., Yamamoto, M., Endo, A., Suzuki, H., Shimada, T.
- Organizer
  14th Annual Meeting of the American Society of Gene & Cell Therapy.
- Place of Presentation
  Seattle, WA
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Intrathecal Administration of Type 9 AAV Vector Expressing Arylsulfatase A Is Effective for Reduction of Sulfatide Storage but Not for Correction of Neurological Deficits inAdult Metachromatic Leukodystrophy Model Mice with Overt Neurological Symptoms.2011
- Author(s)
  Miyake N, Miyake K
- Organizer
  14th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] Intrathecal Administration of Type 9 AAV Vector Expressing Arylsulfatase A Is Effective for Reduction of Sulfatide Storage but Not for Correction of Neurological Deficits in Adult Metachromatic Leukodystrophy Model Mice with Overt Neurological Symptoms2011
- Author(s)
  Miyake N, Miyake K, Sakai A, Yamamoto M, Endo A, Suzuki H, and Shimada T.
- Organizer
  14th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Seattle, WA
- Data Source
  KAKENHI-PROJECT-23591554
[Presentation] Development of adeno-associated viral (AAV) vector mediated muscle directed systemic anti-angiogenic cancer gene therapy2010
- Author(s)
  三宅弘一
- Organizer
  日本癌学会学術総会(第69回)
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] MLL/AF4 Positive Acute Lymphoblastic Leukemia Has Resistance to Tumor Necrosis Factor-Alpha Caused by up-Regration of S100A6.2010
- Author(s)
  Tamai H, Miyake K
- Organizer
  18th European Society of Gene and Cell Therapy Annual Congress
- Place of Presentation
  Prague, Czech
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] Wang Nanya: Development of adeno-associated viral (AAV) vector mediated muscle directed systemic anti-angiogenic cancer gene therapy.2010
- Author(s)
  三宅弘一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] Application of AAV vectors for translational research2010
- Author(s)
  三宅弘一
- Organizer
  日本遺伝子治療学会(第16回)
- Place of Presentation
  宇都宮
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] The Activated K-RAS Protein Accelerates Human Derived-MLL/AF4 Induced Leukemo- Lymphomogenicity In Transgenic Mice Model.2010
- Author(s)
  Tamai H, Miyake K
- Organizer
  18th European Society of Gene and Cell Therapy Annual Congress
- Place of Presentation
  Prague, Czech
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] Systemic injection of AAV type 9 in utero facilitates global gene expression in the CNS.2010
- Author(s)
  Sugano H, Miyake N, Endo A , Miyake K , Shimada T.
- Organizer
  18th European Society of Gene and Cell Therapy Annual Congress.
- Place of Presentation
  Milano,Italy
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Long term correction of biochemical and neurological abnormalities of MLD model mice by systemic neonatal injection of serotype 92010
- Author(s)
  三宅紀子
- Organizer
  American Society of Gene Therapy
- Place of Presentation
  米国・ワシントンDC
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Widespread transduction in the cns and phenotypic correction of mld model mice by systemic neonatal injection of serotype 9 AAV vector.2010
- Author(s)
  Miyake N
- Organizer
  The 16th Annual Meeting of Japan Society of Gene Therapy.
- Place of Presentation
  Tochigi
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Global gene transfer in the CNS and phenotypic correction of MLD model mice by systemic neonatal injection of serotype 9 AAV vector.2010
- Author(s)
  Miyake N, et al
- Organizer
  European Human Genetics Conference
- Place of Presentation
  Gothenburg, Sweden
- Year and Date
  2010-06-14
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] WIDESPREAD TRANSDUCTIONIN THE CNS AND PHENOTYPIC CORRECTION OF MLD MODEL MICE BY SYSTEMIC NEONATAL INJECTION OF SEROTYPE g AAV VECTOR2010
- Author(s)
  三宅紀子
- Organizer
  The 16th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  栃木
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Gene Therapy of Acute Lymphoblastic Leukemia with MLL/AF4 Using AAV8-IL24.2010
- Author(s)
  玉井勇人, 三宅弘一
- Organizer
  第72回日本血液学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] Long term correction of biochemical and neurological abnormalities of MLD model mice by systemic neonatal injection of serotype 9.2010
- Author(s)
  Miyake N, et al
- Organizer
  13th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Washington, DC
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Systemic injection of AAV type 9 in utero facilitates global gene expression in the CNS.2010
- Author(s)
  Sugano H, Miyake N, Endo A , Miyake K , Shimada T.
- Organizer
  International workshop of lysosomal storage disease.
- Place of Presentation
  Prague, Czech
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Development of adeno-associated viral (AAV) vector mediated muscle directed systemic cancer gene therapy2010
- Author(s)
  三宅弘一, et al
- Organizer
  The 69th annual Meeting of the Japanese Cancer Associaton
- Place of Presentation
  Osaka
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Widespread transduction in the CNS and phenotypic correction of MLD model mice by systemic neonatal injection of serotype9 AAV vector.2010
- Author(s)
  Miyake N, et al
- Organizer
  The 16th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Tochigi
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Application of AAV vectors for translational research.2010
- Author(s)
  三宅弘一
- Organizer
  The 16th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Tochigi
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Global gene transfer in the CNS and phenotypic correction of MLD model mice by systemic neonatal injection of serotype 9 AAV vector.2010
- Author(s)
  Miyake N, Miyake K, Asakawa N, Okabe M, Yamamoto M, Shimada T.
- Organizer
  European Human Genetics Conference 2010.
- Place of Presentation
  Gothenburg, Sweden
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Global gene transfer in the CNS and phenotypic correction of MLD model mice by systemic neonatal injection of serotype 9 AAV vector2010
- Author(s)
  三宅紀子
- Organizer
  European Human Genetics Conference
- Place of Presentation
  Sweden, Gothenburg
- Year and Date
  2010-06-14
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Long term correction of biochemical and neurological abnormalities of MLD model mice by systemic neonatal injection of serotype 9.2010
- Author(s)
  Miyake N, Miyake K, Asakawa N, Yamamoto M, Shimada T.
- Organizer
  13th Annual Meeting of the American Society of Gene & Cell Therapy.
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Development of adeno-associated viral (AAV) vectormediated muscle directed systemic anti-angiogenic cancer gene therapy.2010
- Author(s)
  Miyake K
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] AAV Vector Mediated Enzyme Replacement Therapy of Hypophosphatasia (HPP) Model Mice.2010
- Author(s)
  Matsumoto T, Yamamoto S, Orimo H, Miyake K, Miyake N, Narisawa S, Millan JL, Fukunaga Y, Shimada T.
- Organizer
  13th Annual Meeting of the AmericanSociety of Gene & Cell Therapy.
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Establishment and Characterization of A New Lymphoid Malignancy Mouse Model Induced by thecombination of MLL/AF4 and K-RAS.2010
- Author(s)
  玉井勇人, 三宅弘一
- Organizer
  第72回日本血液学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22591444
[Presentation] The Activated K-RAS protein accelerates human derived-MLL/AF4 induced leukemo-lymphomogenicity in transgenic mice model.2010
- Author(s)
  Tamai H, Miyake K, et al
- Organizer
  The 52th American Society of Hematology Annual Meeting
- Place of Presentation
  Orlando, USA
- Year and Date
  2010-12-06
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Adeno associated virus (AAV)-mediated neonatal gene therapy of metachromatic leukodystrophy2009
- Author(s)
  三宅紀子、三宅弘一, 他3名
- Organizer
  59th Annual Meeting of the American Society of Human genetics
- Place of Presentation
  Hawaii
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Direct comparison of adeno-associated virus serotypes for global gene transfer into the CNS across the BBB after neonatal systemic delivery2009
- Author(s)
  三宅紀子、三宅弘一, 他3名
- Organizer
  The 15th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  大阪
- Year and Date
  2009-07-09
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Adeno-associated vector (type 8) mediated expression of flt-1 efficiently inhibits neovascularization in a murine choroidal neovascularization model2009
- Author(s)
  五十嵐勉、三宅弘一, 他4名
- Organizer
  The 15th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  大阪
- Year and Date
  2009-07-09
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Adeno associated virus (AAV)-mediated neonatal gene therapy of metachromatic leukodystrophy.2009
- Author(s)
  Miyake N, et al
- Organizer
  59th Annual Meeting of the American Society of Human genetics
- Place of Presentation
  Hawaii
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] MLL/AF4遺伝子異常を伴う急性リンパ性白血病のMDA7/IL24による遺伝子治療2009
- Author(s)
  玉井勇人、三宅弘一, 他3名
- Organizer
  第71回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Establishment and characterization of a new mouse leukemia model induced by MLL/AF4 fusion protein2009
- Author(s)
  玉井勇人、三宅弘一, 他5名
- Organizer
  51th American Society of Hematology Annual Meeting
- Place of Presentation
  New Orleans
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Efficient correction of cardiac abnormalities in Fabry mice by AAV type8 mediated systemic gene transfer2009
- Author(s)
  三宅弘一、三宅紀子, 他5名
- Organizer
  The 15th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  大阪
- Year and Date
  2009-07-09
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Adeno-associated virus (AAV) type8 mediated systemic neonatal gene therapy for hypophosphatasia2009
- Author(s)
  松本多絵、三宅弘一, 他5名
- Organizer
  59th Annual Meeting of the American Society of Human genetics
- Place of Presentation
  Hawaii
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Direct comparison of adeno-associated virus serotypes for global gene transfer into the CNS across the BBB after neonatal systemic delivery2009
- Author(s)
  Miyake N, et al
- Organizer
  The 15th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Osaka
- Year and Date
  2009-07-09
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Efficient correction of cardiac abnormalities in Fabry mice by AAV type8 mediated systemic gene transfer2009
- Author(s)
  三宅弘一, 他5名
- Organizer
  The 15th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  大阪
- Year and Date
  2009-07-09
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Adeno-associated virus (AAV) type8 mediated systemic neonatal gene therapy for hypophosphatasia2009
- Author(s)
  松本多絵、三宅紀子, 他5名
- Organizer
  59th Annual Meeting of the American Society of Human genetics
- Place of Presentation
  Hawaii
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Adeno-associated virus (AAV) mediated neonatal gene therapy of metachromatic leukodystrophy2009
- Author(s)
  三宅紀子、三宅弘一, 他2名
- Organizer
  The 3rd International Symposium of Lysosomal Storage Diseases
- Place of Presentation
  名古屋
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Direct comparison of adeno-associated virus serotypes for global gene transfer into the CNS across the BBB after neonatal systemic delivery2009
- Author(s)
  Miyake N, et al
- Organizer
  The 12th Annual Meeting of American ety of Gene Therapy
- Place of Presentation
  San Diego
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Adeno-associated virus (AAV) type-8 mediated systemic neonatal gene therapy for hypophosphatasia2009
- Author(s)
  松本多絵、三宅紀子, 他4名
- Organizer
  The 15th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  大阪
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Adeno-associated virus (AAV) mediated neonatal gene therapy of metachromatic leukodystrophy2009
- Author(s)
  三宅紀子、三宅弘一, 他2名
- Organizer
  The 3rd International Symposium of Lysosomal Storage Diseases
- Place of Presentation
  名古屋
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Direct comparison of adeno-associated virus serotypes for global gene transfer into the CNS across the BBB after neonatal systemic delivery2009
- Author(s)
  三宅紀子、三宅弘一, 他3名
- Organizer
  12th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  San Diego
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Adeno-associated virus (AAV) type-8 mediated systemic neonatal gene therapy for hypophosphatasia2009
- Author(s)
  松本多絵、三宅弘一, 他4名
- Organizer
  The 15th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  大阪
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Establishment of a mouse model for MLL-AF4 fusion protein induced leulemia2009
- Author(s)
  玉井勇人、三宅弘一, 他2名
- Organizer
  The 15th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  大阪
- Year and Date
  2009-07-10
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Direct comparison of adeno-associated virus serotypes for global gene transfer into the CNS across the BBB after neonatal systemic delivery2009
- Author(s)
  三宅紀子、三宅弘一, 他3名
- Organizer
  12th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  San Diego
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Direct comparison of adeno-associated virus serotypes for global gene transfer into the CNS across the BBB after neonatal systemic delivery2009
- Author(s)
  三宅紀子、三宅弘一, 他3名
- Organizer
  The 15th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  大阪
- Year and Date
  2009-07-09
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Efficient correction of cardiac abnormalities in Fabry mice by AAV type8 mediated systemic gene transfer.2009
- Author(s)
  三宅弘一, et al
- Organizer
  The 15th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Osaka
- Year and Date
  2009-07-09
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Adeno-associated virus (AAV) type8 mediated systemic neonatal gene therapy for hypophosphatasia.2009
- Author(s)
  Matsumoto T, Miyake K, et al
- Organizer
  59th Annual Meeting of the American Society of Human genetics
- Place of Presentation
  Hawaii
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Establishment and characterization of a new mouse leukemia model induced by MLL/AF4 fusion protein2009
- Author(s)
  玉井勇人、三宅紀子, 他5名
- Organizer
  51th American Society of Hematology Annual Meeting
- Place of Presentation
  New Orleans
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Adeno-associated virus (AAV) mediated neonatal gene therapy of metachromatic leukodystrophy.2009
- Author(s)
  Miyake N, et al
- Organizer
  The 3rd International Symposium of Lysosomal Storage Diseases
- Place of Presentation
  Nagoya
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Direct comparison of adeno-associated virus serotypes for global gene transfer into the CNS across the BBB after neonatal systemic delivery2009
- Author(s)
  三宅紀子、三宅弘一, 他3名
- Organizer
  59th Annual Meeting of the American Society of Human genetics
- Place of Presentation
  Hawaii
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Direct comparison of adeno-associated virus serotypes for systemic delivery by long term monitoring of in vivo quantitative noninvasive imaging.2008
- Author(s)
  三宅弘一, et al
- Organizer
  The 11th Annual Meeting of the American Society of Gene Therapy
- Place of Presentation
  Boston, USA
- Year and Date
  2008-05-29
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Development of adeno-associated viral (AAV) vector mediated anti-angiogenic systemic cancer gene therapy.2008
- Author(s)
  三宅弘一, et al
- Organizer
  The 14th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Sapporo
- Year and Date
  2008-07-13
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Induction of immunotolerance and sustained expression of ASA by single intra venous injection of AAV vector in neonatal immunocompetent mice.2008
- Author(s)
  三宅紀子
- Organizer
  American Society of Gene Therapy
- Place of Presentation
  米国・ボストン
- Data Source
  KAKENHI-PROJECT-20591234
[Presentation] Direct comparison of adeno-associated virus serotypes for systemic delivery by long term monitoring of in vivo quantitative noninvasive imaging.2008
- Author(s)
  三宅, 弘一
- Organizer
  11th Annual Meeting of the American Society of Gene Therapy
- Place of Presentation
  米国・ボストン
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Adeno-associated virus (AAV) serotypes : In vivo expression and tropism in mice.2008
- Author(s)
  三宅弘一
- Organizer
  The 14th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Sapporo
- Year and Date
  2008-07-13
- Data Source
  KAKENHI-PROJECT-20591265
[Presentation] Direct comparison of adeno-asociated virus serotype for systemic delivery by monitoring of in vivo quantitative noninvasive imaging2007
- Author(s)
  Miyake K
- Organizer
  The 13th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Nagoya,Japan
- Year and Date
  2007-06-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591204
[Presentation] Direct comparison of adeno-asociated virus serotype for systemic delivery by monitoring of in vivo quantitative noninvasive imaging2007
- Author(s)
  Miyake, K
- Organizer
  The 13th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Nagoya, Japan
- Year and Date
  2007-06-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591204
[Presentation] Gene therapy of adult MLD model mice by intrathecal administration of type 9 AAV vector.
- Author(s)
  Miyake, N.
- Organizer
  15th Annual Meeting of the American Society of Gene & CellTherapy.
- Place of Presentation
  Philadelphia,Pennsylvania
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Successful Treatment of Adult MLD Model Mice By Intravenous Injection of Self-Complementary Type 9 AAV Vector Expressing ASA.
- Author(s)
  Miyake N, Miyake K, Yamamoto M, Shimada T.
- Organizer
  17th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Washington DC
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26461596
[Presentation] Gene therapy of adult MLD model mice by intrathecal administration of type 9 AAV vector.
- Author(s)
  Miyake, N.
- Organizer
  第4回国際ライソゾーム病フォーラム・第17回日本ライソゾーム病研究会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Efficient Protection of Retina By Tyrosine-Mutated Self-Complementary AAV2 Vector Encoding BDNF in a Rat Retinal Ischemic Injury Model.
- Author(s)
  Igarashi T, Miyake K, Kobayashi M, Takahashi K, Miyake N, Iijima O, Nakamoto K, Hirai Y, Shimada T, Takahashi H.
- Organizer
  17th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Washington DC
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26461596
[Presentation] Rescue of lethal hypophosphatasia model mice by adeno-associated virus mediated muscle specific expression of bone targeted alkaline phosphatase.
- Author(s)
  Nakamura A, Iijima O, Miyake K, Watanabe A, Hirai Y, Kinoshita H, Noguchi T, Abe S, Okada T, Shimada T.
- Organizer
  American Society of Human Genetics Annual Meeting (64th)
- Place of Presentation
  San Diego Convention Center（San Diego, CA）
- Year and Date
  2014-10-18 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-25461564
[Presentation] Long-term enzyme supplementation into the CSF to treat metachromatic leukodystrophy by intraventricular injection of AAV1 vector.
- Author(s)
  Yamazaki Y, Hironaka K, Miyake N, Hirai Y, Miyake K, Okada T, Shimada T.
- Organizer
  The 20th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  東京
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-26461596
[Presentation] Neonatal transplantation of lentivirally transduced bone marrow cells for the treatment of lethal hypophosphatasia mice.
- Author(s)
  Iijima O, Miyake K, Watanabe A, Nakamura A, Igarashi T, Kanokoda C, Kinoshita H, Noguchi T, Abe S, Okada T, Shimada T.
- Organizer
  日本遺伝子治療学会学術集会（第20回）
- Place of Presentation
  東京慈恵会医科大学（東京都）
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25461564
[Presentation] Successful Treatment of Adult MLD Model Mice By Intravenous Injection of Self-Complementary Type 9 AAV Vector Expressing ASA
- Author(s)
  Miyake N, Miyake K, Yamamoto M, Shimada T.
- Organizer
  17th Annual Meeting of the American Society of Gene & Cell Therapy
- Place of Presentation
  Washington DC
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] Trans-BBB gene therapy for metachromatic leukodystrophy using self-complementary type 9 AAV vector.
- Author(s)
  Miyake N, Miyake K, Yamamoto M, Okada T, Shimada T.
- Organizer
  The 20th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  東京
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-26461596
[Presentation] The D816V c-kit mutation confers higher proliferation activity by JAK-STAT and Src family kinase pathway compared to N822K c-kit mutation in core-binding factor acute myeloid leukemia.
- Author(s)
  Omori I, Yamaguchi H, Kitano T, Miyake N, Miyake K, Inokuchi K.
- Organizer
  56th ASH Annual Meeting & Exposition
- Place of Presentation
  San Francisco, CA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-26461596
[Presentation] Improvement of hypophosphatasia model mice by muscle specific expression of bone targeted alkaline phosphatase using self-complementary AAV8 vector.
- Author(s)
  Nakamura A, Iijima O, Miyake K, Watanabe A, Hirai Y, Kinoshita H, Noguchi T, Abe S, Okada T, Shimada T.
- Organizer
  日本遺伝子治療学会学術集会（第20回）
- Place of Presentation
  東京慈恵会医科大学（東京都）
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25461564
[Presentation] Trans-BBB gene therapy for metachromatic leukodystrophy using self-complementary type 9 AAV vector
- Author(s)
  Miyake N, Miyake K, Yamamoto M, Okada T, Shimada T.
- Organizer
  The 20th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  東京
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-24591529
[Presentation] AAV9 mediated gene therapy of MLD model mice.
- Author(s)
  Miyake, N.
- Organizer
  20th Annual Meeting of the European Society of Gene & CellTherapy.
- Place of Presentation
  Versailles,France
- Data Source
  KAKENHI-PROJECT-22390212
[Presentation] Successful treatment of adult MLD model mice by intrathecal administration of AAV9 vector.
- Author(s)
  Miyake, N.
- Organizer
  第18回日本遺伝子治療学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22390212
[]

1. SHIMADA Takashi (20125074)

# of Collaborated Projects: 7 results

# of Collaborated Products: 49 results
2. TERASAKI Yasuhiro (50332870)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
3. MIYAKE Noriko (00421206)

# of Collaborated Projects: 4 results

# of Collaborated Products: 69 results
4. TERASAKI Mika (50372785)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
5. MIGITA Makoto (50256963)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. WATANABE Atsushi (10307952)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
7. KUNUGI Shinobu (30350036)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
8. MODHIZUKI Hideki (90230044)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. NAGASAKA Shinya (00573239)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. 塙秀樹 (10256977)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. 早坂明哲 (50516094)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 藤倉輝道 (00238552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 根本崇宏 (40366654)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 藤崎弘士 (60573243)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. AIMOTO Takayuki (10267122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. ORIKASA Chitose (20270671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TAKAHASHI Mikiko (40516077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. MATSUI Shoko (40334726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KANAZAWA Satoshi (90347401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. Iijima Osamu (40466206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
21. TOHYAMA Takashi (60167525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. NISHI Katsunori (00138257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. NAGASHIMA Masakazu (20256952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TAKANASHI Hioshi (00277534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Matsumoto Tae (10366742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. Sakai Atsushi (30386156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. Yamaguchi Hiroki (90297937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
28. SEIKE MASAHIRO (30366687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. ISHIKAWA ARIMI (40598992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KUWAHARA NAOMI (00599011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 佐久間康夫 (70094307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 福田悠 (60097037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
33. 漆山博和 (20725303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 平井幸彦 (10089617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
35. 鈴木聡 (70246940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
36. 加藤興 (10267148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 久安早苗 (00089616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 猪口孝一 (10203267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
39. 渡辺憲太朗 (80158625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 井上千鹿子 (90453042)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 高久俊 (50445813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. OGURA Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. Terada Kazuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
44. 家田真樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 岡田尚已

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 岡田浩典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 丸山基世

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 鈴木秀典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 坂本篤裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIYAKE Koichi 三宅 弘一

三宅 弘一 ミヤケ コウイチ

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Development of gene therapy for hypophosphatasiaPrincipal Investigator

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Development of mouse model and therapy of Diamond-Blackfan anemiaPrincipal Investigator

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MIYAKE Koichi 三宅弘一

三宅弘一ミヤケコウイチ