oorui takashi 大類孝

… Alternative Names

OHRUI Takashi 大類孝

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Researcher Number	90271923
External Links
Affiliation (Current)	2025: 東北医科薬科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2017 – 2018: 東北医科薬科大学, 医学部, 教授 2014 – 2016: 東北大学, 加齢医学研究所, 教授 2008 – 2010: Tohoku University, 加齢医学研究所, 准教授 2004 – 2006: TOHOKU UNIVERSITY, HOSPITAL, ASSOCIATE PROFESSOR, 病院, 助教授 2003: 東北大学, 医学部附属病院, 助教授 … More 2002: Tohoku University Hospital Research Associate, 医学部附属病院, 助手 2001: 東北大学, 医学部・附属病院, 助手 1996 – 1997: 東北大学, 医学部・附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / General internal medicine (including Psychosomatic medicine) / Respiratory organ internal medicine / General internal medicine(including psychosomatic medicine) / Infectious disease medicine Except Principal Investigator General internal medicine(including psychosomatic medicine)
Keywords	Principal Investigator 高齢者 / 肺炎 / ツベルクリン反応 / 虚弱高齢者 / 細胞性免疫 / 高齢者肺炎 / ACE inhibitor / Somatostatin / Cognitive function / Cerebrospinal fluid … More / ACE activity / Mild cognitive impairment / Alzheimer's disease / ソマトスタチン / 認知機能 / 脳内移行性ACE阻害剤 / 脳脊髄液中ACE活性 / 脳内ACE活性 / 軽度認知障害(MCI) / アルツハイマー病 / Tuberculin responses / BCG vaccination / Cellular immunity / Pneumonia / Older people / BCGワクチン / exaled CO concentration / anti-coagulant therapy / oxidative stress / D-dimer / pulmonary microthromboembolism / respiratory failure / older subject / Influenza A virus / 呼気中一酸化炭素濃度 / 抗凝固療法 / 酸化ストレス / D-ダイマー / 微小血栓塞栓症 / 呼吸不全 / インフルエンザ / inflammatory cells / Late airway response / antigen challenge / Brown Norway rat / estrogen / Progesterone / premenstrual asthma / Bronchial asthma / 好酸球浸潤 / ロイコトリエン / 遅発型喘息反応 / 抗原チャレンジ / ブラウンノルウェーラット / エストローゲン / プロゲステロン / 月経期喘息 / 気管支喘息 / 放射線治療 / 前立腺癌 / 白血球数 / アンサー / 活性型ビタミンD3 / 生命予後 / 活性型ビタミンD製剤 / 血中ビタミンD濃度 / 25-OHビタミンD / 活性型ビタミンD / 細胞性免疫能 / ビタミンD欠乏 / ビタミンD / 感染症予防学 … More Except Principal Investigator ソーシャル・キャピタル / ヘルスリテラシー / 認知機能 / 大規模災害 / 津波 / フレイル / 健康調査 / 気仙沼市 / 認知症 / 基本チェックリスト / 高齢者 / 災害公営住宅 / 東日本大震災 Less

Establishment of the system managing the health of the elderlies lived in the public restoration housing.
- Principal Investigator
  
  Okinaga Shoji
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Tohoku University
A pilot study examining the effect of Ancer for the prevention of elderly pneumoniaPrincipal Investigator
- Principal Investigator
  
  OHRUI Takashi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Tohoku Medical and Pharmaceutical University
  Tohoku University
Effect of vitamin D supplementation on the clinical conditions in the institutionalized elderly subjectsPrincipal Investigator
- Principal Investigator
  
  OHRUI Takashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Tohoku University
ACE activity in CSF of patients with MCI, AD or controls.Principal Investigator
- Principal Investigator
  
  OHRUI Takashi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  TOHOKU UNIVERSITY
Prevention of elderly pneumonia by BCG vaccinationPrincipal Investigator
- Principal Investigator
  
  OHRUI Takashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  TOHOKU UNIVERSITY
Study on the pulmonary microvascular thromboembolism associated with severe influenza virus infection in the elderlyPrincipal Investigator
- Principal Investigator
  
  OHRUI Takashi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University
Mechanisms for premenstrual exacerbation of asthamaPrincipal Investigator
- Principal Investigator
  
  OHRUI Takashi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University

All 2016 2011 2010 2009 2006 2005 2004 2003

All Journal Article Presentation Book Patent

[Book] 高齢者の肺炎(松本慶蔵総監修)2011
- Author(s)
  大類孝
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-20390285
[Book] 高齢者の肺炎2011
- Author(s)
  大類孝(松本慶蔵総監修)
- Publisher
  ジャーナル社
- Data Source
  KAKENHI-PROJECT-20390285
[Journal Article] A Heterodimeric Cytokine, Consisting of IL-17A and IL-17F, Promotes Migration and Capillary-Like Tube Formation of Human Vascular Endothelial Cells2016
- Author(s)
  Numasaki M, Tsukamoto H, Tomioka Y, Nishioka Y, Ohrui T.
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 240 Issue: 1 Pages: 47-56
- DOI
  10.1620/tjem.240.47
- NAID
  130005261734
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05309, KAKENHI-PROJECT-26460058, KAKENHI-PROJECT-26670418, KAKENHI-PROJECT-26460900
[Journal Article] Antitumor immunity elicited by direct intratumoral administration of a recombinant adenovirus expressing either IL-28A/IFN-λ2 or IL-29/IFN-λ1.2016
- Author(s)
  Hasegawa K, Tagawa M, Takagi K, Tsukamoto H, Tomioka Y Suzuki T,　Nishioka Y, Ohrui T, Numasaki M.
- Journal Title
  
  Cancer Gene Therapy.
  
  Volume: ２３ Pages: 266-277
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460900
[Journal Article] 高齢者肺炎・誤嚥性肺炎2010
- Author(s)
  大類孝
- Journal Title
  
  日本内科学雑誌
  
  Volume: 99 Pages: 2746-2751
- NAID
  10027509111
- Data Source
  KAKENHI-PROJECT-20390285
[Journal Article] Low serum 1,25-dihydroxyvitamin D level and risk of respiratory infections in institutionalized older people.2010
- Author(s)
  Asamura T, Ohrui T, et al.
- Journal Title
  
  Gerontology Jan 12(Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390285
[Journal Article] Low serum 1,25-dihydroxyvitamin D level and risk of respiratory infections in institutionalized older people.2010
- Author(s)
  Asamura T, Ohrui T, Nakayama K, He M, Yamasaki M, Ebihara T, Ebihara S, Furukawa K, Arai H.
- Journal Title
  
  Gerontology 56
  
  Pages: 542-543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390285
[Journal Article] A randomized, single-blind study of lansoprazole for the prevention of exacerbations of chronic obstructive pulmonary disease in older patients.2009
- Author(s)
  Sasaki T, Nakayama K, Yasuda H, Yoshida M, Asamura T, Ohrui T, Arai H, Araya J, Kuwano K, Yamaya M.
- Journal Title
  
  J Am Geriatr Soc 57
  
  Pages: 1453-1457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390285
[Journal Article] 誤嚥性肺炎予防の新戦略2009
- Author(s)
  大類孝、海老原覚、海老原孝枝、浅村孝昭、宇根かおり、矢満田慎介、吉田元樹、山崎都、浅田成紀、高橋秀徳、荒井啓行
- Journal Title
  
  呼吸 28
  
  Pages: 250-254
- Data Source
  KAKENHI-PROJECT-20390285
[Journal Article] Homicides of frail older persons by their caregivers in Japan2009
- Author(s)
  He M, Ohrui T, Arai H.
- Journal Title
  
  Journal of the American Geriatrics So ciety 57
  
  Pages: 173-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390285
[Journal Article] 誤嚥性肺炎予防の新戦略2009
- Author(s)
  大類孝、海老原覚、海老原孝枝、他
- Journal Title
  
  呼吸 28
  
  Pages: 250-254
- Data Source
  KAKENHI-PROJECT-20390285
[Journal Article] ACE阻害薬は認知能力を保持する2006
- Author(s)
  大類孝
- Journal Title
  
  呼吸と循環 54巻
  
  Pages: 369-374
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590591
[Journal Article] Caregivers murder the frail elderly in Japan.2005
- Author(s)
  Ohrui T, et al.
- Journal Title
  
  J Am Geriatr Soc 53
  
  Pages: 553-554
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590794
[Journal Article] Homicides of disabled older persons by their caregivers in Japan.2005
- Author(s)
  Ohrui T.et al.
- Journal Title
  
  J Am Geriatr Soc 53
  
  Pages: 553-554
- Data Source
  KAKENHI-PROJECT-17590591
[Journal Article] Cognitive decline in patients with long-term domiciliary oxygen therapy.2005
- Author(s)
  Ohrui T.et al.
- Journal Title
  
  Tohoku J Exp Med 206
  
  Pages: 347-352
- NAID
  10016478033
- Data Source
  KAKENHI-PROJECT-17590591
[Journal Article] Interventions to prevent pneumonia in older adults.2004
- Author(s)
  Ohrui T.
- Journal Title
  
  Geriatr Gerontol Internat 4
- NAID
  10018027271
- Data Source
  KAKENHI-PROJECT-15590794
[Journal Article] Relation between retirement and subsequent health Status in highly educational older man.2004
- Author(s)
  Ohrui T, et al.
- Journal Title
  
  J Am Geriatr Soc 52
  
  Pages: 2145-2147
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590794
[Journal Article] Interventions to prevent pneumonia in older adults.2004
- Author(s)
  Ohrui T, et al.
- Journal Title
  
  Geriatr Gerontol Internat 4
- NAID
  10018027271
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590794
[Journal Article] Relation between retirement and subsequent health status in highly educational older man.2004
- Author(s)
  Ohrui T, et al.
- Journal Title
  
  J Am Geriatr Soc 52
  
  Pages: 2145-2147
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590794
[Patent] 細胞性免疫を賦活化させる方法2003
- Inventor(s)
  大類孝他2名
- Industrial Property Rights Holder
  東北大学長
- Industrial Property Number
  2003-109250
- Filing Date
  2003-12-15
- Data Source
  KAKENHI-PROJECT-15590794
[Patent] 細胞性免疫を賦活化させる方法2003
- Inventor(s)
  大類孝他2名
- Industrial Property Rights Holder
  東北大学長
- Industrial Property Number
  2003-109250
- Filing Date
  2003-12-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590794
[Presentation] 高齢者認知機能の保護および肺炎予防の新戦略2009
- Author(s)
  大類孝
- Organizer
  日本循環器学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-03-22
- Data Source
  KAKENHI-PROJECT-20390285
[Presentation] 高齢者肺炎の発症における活性型ビタミンDの役割に関する検討2009
- Author(s)
  浅村孝昭, 大類孝
- Organizer
  第51回日本老年医学会学術集会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-20390285
[Presentation] 高齢者肺炎の発症における活性型ビタミンDの役割に関する検討2009
- Author(s)
  浅村孝昭、大類孝
- Organizer
  第49回日本呼吸器学会学術講演会一般演題
- Place of Presentation
  東京
- Year and Date
  2009-06-13
- Data Source
  KAKENHI-PROJECT-20390285
[Presentation] 高齢者肺炎の発症における活性型ビタミンDの役割に関する検討2009
- Author(s)
  浅村孝昭, 大類孝
- Organizer
  第49回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム(東京)
- Year and Date
  2009-06-13
- Data Source
  KAKENHI-PROJECT-20390285
[Presentation] 高齢者肺炎の発症における活性型ビタミンDの役割に関する検討2009
- Author(s)
  浅村孝昭、大類孝
- Organizer
  第51回日本老年医学会学術集会一般演題
- Place of Presentation
  横浜
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-20390285

1. 松下晴雄 (20302250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. Okinaga Shoji (30302136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 冨田尚希 (00552796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 古川勝敏 (30241631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

oorui takashi 大類 孝

OHRUI Takashi 大類 孝

Research Projects

Research Products

Co-Researchers

Establishment of the system managing the health of the elderlies lived in the public restoration housing.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A pilot study examining the effect of Ancer for the prevention of elderly pneumoniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of vitamin D supplementation on the clinical conditions in the institutionalized elderly subjectsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ACE activity in CSF of patients with MCI, AD or controls.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prevention of elderly pneumonia by BCG vaccinationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the pulmonary microvascular thromboembolism associated with severe influenza virus infection in the elderlyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms for premenstrual exacerbation of asthamaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 高齢者の肺炎(松本慶蔵総監修)2011

Author(s)

Publisher

Data Source

[Book] 高齢者の肺炎2011

Author(s)

Publisher

Data Source

[Journal Article] A Heterodimeric Cytokine, Consisting of IL-17A and IL-17F, Promotes Migration and Capillary-Like Tube Formation of Human Vascular Endothelial Cells2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Antitumor immunity elicited by direct intratumoral administration of a recombinant adenovirus expressing either IL-28A/IFN-λ2 or IL-29/IFN-λ1.2016

Author(s)

Journal Title

Data Source

[Journal Article] 高齢者肺炎・誤嚥性肺炎2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Low serum 1,25-dihydroxyvitamin D level and risk of respiratory infections in institutionalized older people.2010

Author(s)

Journal Title

Data Source

[Journal Article] Low serum 1,25-dihydroxyvitamin D level and risk of respiratory infections in institutionalized older people.2010

Author(s)

Journal Title

Data Source

oorui takashi 大類孝

OHRUI Takashi 大類孝